Proceedings of the ASME

Summer Bioengineering Conference

- 2011 -

Part A

presented at

ASME 2011 SUMMER BIOENGINEERING CONFERENCE

JUNE 22-25, 2011

FARMINGTON, PENNSYLVANIA, USA

sponsored byASME BIOENGINEERING DIVISION

ASME

Three Park Avenue New York, N.Y. 10016

CONTENTS

PART A

ARTERIAL MECHANICS

SBC2011-53140 1

Mechanics and Modeling of Postnatal Arterial Development in Wild-Type and

Elastin-lnsufficient Mice

Jeffrey K. Cheng, Victoria Le, Robert P. Mecham, and Jessica E. Wagenseil

SBC2011-53357 3

Penetration Mechanics of Endovascular Stent Graft Barbs in Aortic Tissue

Kathleen Lin, Benjamin Berkowitz, and Madhavan L Raghavan

SBC2011-53403 5

Layer-Specific Distributed Collagen Fiber Orientations in Human Arteries, From Thoracic

Aorta to Common Iliac

Andreas J. Schriefl, Peter Regitnig, David M. Pierce, and Gerhard A. Holzapfel

SBC2011-53440 7

An Investigation on the Use of Silicone to Model Arterial Tissue Behaviour in the Idealised

Tuning-Fork Model of the Carotid Bifurcation

J. J. Mulvihill, M. R. O'Donnell, B. M. O'Connell, and M. T. Walsh

SBC2011-53652 ,9

Buckling Behavior of Arteries Under Torsion

Justin R. Garcia, Shawn D. Lamm, and Hai-Chao Han

SBC2011-53705 11

A New Form of Residual Deformation in the Coronary Artery: Implications for In Vivo

Mechanical Behavior

Ruoya Wang and Rudolph L. Gleason

ATHEROSCLEROSIS I

SBC2011-53161 13

Degree of Retrograde Flow and Its Effect on Local Hemodynamics and Plaque Distribution

in an Aortic Regurgitation Murine Model of Atherosclerosis

Yiemeng Hoi, Mark van Doormaal, Yu-Qing Zhou, Xiaoli Zhang, R. Mark Henkelman, and

David A. Steinman

SBC2011-53232 15

On the Use of In Vivo Measured Flow Rates as Boundary Conditions for Image-Based

Hemodynamic Models of the Human Aorta

Diego Gallo, Gianluca De Santis, Federica Negri, Daniele Tresoldi, Giovanna Rizzo,

Raffaele Ponzini, Diana Massai, Marco Deriu, Marcello Cadioli, Benedict Verhegghe,

Patrick Segers, Alberto Redaelli, and Umberto Morbiducci

v

SBC2011-53243 17

Rightward and Leftward Head Rotation Influence the Geometric Features of the HealthyCarotid Bifurcation

Nicolas Aristokleous, loannis Seimenis, Yannis Papaharilaou, Georgios Georgiou,

Brigitta C. Brott, and Andreas S. Anayiotos

SBC2011-53469 19

Database of Rabbit Aortic Geometries for Use in Computational Flow Studies

V, Peiffer, M. Rowland, P. D. Weinberg, and S. J. Sherwin

SBC2011-53528 21

Geometric and Hemodynamic Evaluation of 3-Dimensional Reconstruction Techniquesfor the Assessment of Coronary Artery Wall Shear Stress in the Setting of

Clinical Disease ProgressionLucas H. Timmins, Jin Suo, Parham Eshtehardi, Saurabh S. Dhawan, Michael C. McDaniel,

John N. Oshinski, Habib Samady, and Don P. Giddens

SBC2011-53865 23

Thrombus Initiation With Subsequent Growth Measured for Physiological Shear and

High Pathological Shear

David L. Bark, Jr., Andrea N. Para, and David N. Ku

ATHEROSCLEROSIS II

SBC2011-53078 25

Stress-Strain Profile of Carotid Plaque With and Without Juxtaluminal

Hemorrhage/Thrombus: A Possible Mechanism for Subsequent Cerebrovascular Events

Zhongzhao Teng, Umar Sadat, and Jonathan Gillard

SBC2011-53098 27

A Predictive Method for Human Carotid Plaque Rupture Using In Vivo Serial MRI With

Follow-Up Scan Showing Actual Rupture and MRI-Based 3D Models With Fluid-Structure

Interactions

Zheyang Wu, Chun Yang, and Dalin Tang

SBC2011-53143 29

Risk of Rupture in Coronary Vulnerable Plaques: Fluid-Structure Interaction Studies UsingPatient Based Micro-CT and IVUS Measurements

Xuan Liang, Suraj Rambhia, Michalis Xenos, Yared Alemu, Natalia Maldonado,

Adreanne Kelly, Ifat Lavi, Shmuel Einav, Sheldon Weinbaum, Luis Cardoso, and

Danny Bluestein

SBC2011-53198 31

Human Coronary Microcalcifications: 3D High Resolution Characterization of FrequencySize and Distribution

Natalia Maldonado, Adreanne Kelly, Yuliya Vengrenyuk, John T. Fallon, Renu Virmani,

Luis Cardoso, and Sheldon Weinbaum

SBC2011-53639 33

Correlation Between Plaque Composition and Shear Stress Using Three-Dimensional

Reconstructed Histology and Computational Fluid Dynamics of Diseased Human

Carotid Arteries

Kim van der Heiden, Harald C. Groen, Lambert Speelman, Aad van der Lugt,Anton F. W. van der Steen, Wiro Niessen, Frank J. H. Gijsen, and Jolanda J. Wentzel

vi

SBC2011-53750 35

Three Dimensional Reconstruction of the Components of the Carotid Plaque From Standard

CT Medical Images

Dipankar Biswas, Francis Loth, Susan McCormick, and Hisham Bassiouny

BIOHEAT TRANSFER AND BIONANOTECHNOLOGY

SBC2011-53102 37

Enhanced Transmucosal Transport Using Osmolyte-Mediated Fluid-Matrix Interaction

Ka Yaw Teo, Basma Ibrahim, Seungman Park, Yeo Yoon, and Bumsoo Han

SBC2011-53156 39

Attachment State Shifts Viability Versus Cooling Rate (Inverted U Curve) During Freezingfor Human Dermal Fibroblasts

Jeunghwan Choi and John C. Bischof

SBC2011-53319 41

Temperature Field Reconstruction for the Application of Wireless Implantable TemperatureSensors in Cryosurgery

Chandrajit Thaokar and Yoed Rabin

SBC2011-53845 43

Hydraulic Resistance of a Novel Hollow-Core Microneedle DesignR. L Hood, M. A. Kosoglu, and C. G. Rylander

SBC2011-53968 45

Synthesis and Cytotoxicity Analysis of Carbon Nanohorn-Quantum Dot ComplexesKristen A. Zimmermann, Jianfei Zhang, Harry Dorn, Christopher Rylander, and

Marissa Nichole Rylander

SBC2011-54011 47

Enrichment of Cancer Cells Using a High Throughput Contactless Dielectrophoretic (CDEP)Microfluidic Device

Alireza Salmanzadeh, Hadi Shafiee, Mike B. Sano, Mark A. Stremler, andRafael V. Davalos

BIOLOGICAL INTERFACES: MECHANICS AND SYNTHESIS

SBC2011-53704 49

A Modular System to Examine Fibroblastic Differentiation of Mesenchymal Stem Cells

Under Tensile Loading in Response to Changes in the Extracellular Environment

Johnna S. Temenoff

SBC2011-53737 51

Hydration and Crosslinking Effects on the Elastic and Viscoelastic Properties of

Collagen Scaffolds

Bin Xu and Katherine Yanhang Zhang

SBC2011-53774 53

Material Properties of the Developing Bone-Cartilage Interface in the Human Fetal SpineRachel C. Paietta, Evalina Burger, and Virginia L. Ferguson

vii

SBC2011-53991 55

On the Mechanics of Partially Mineralized Tissues and Their Implications for the

Attachment of Tendon to Bone

Yanxin Liu, Victor Birman, Chanqing Chen, Stavros Thomopoulos, and Guy M. Genin

SBC2011-54009 57

Directed Cellular Dynamics on Aligned STEP Fibrous Mechanistic Microenvironments

Kevin Sheets and Amrinder Nain

SBC2011-54026 59

Collagen Scaffold-Membrane Composites for Mimicking Orthopedic Interfaces

Brendan A. C. Harley

BIOMECHANICS OF AORTIC ANEURYSMS

SBC2011-53268 61

Use of the Photoelastic Method to Determine the Wall Stress in Realistic Abdominal

Aortic Aneurysm Models

Barry J. Doyle, Anthony Callanan, John Killion, and Timothy M. McGloughlin

SBC2011-53525 63

A Growth and Remodeling Approach to AAA Modeling: Feasibility and Initial InsightsJohn S. Wilson, Seungik Baek, and Jay D. Humphrey

SBC2011-53576 65

Quantifying the Structural and Mechanical Changes in Elastase Degraded Arteries as an

In Vitro Model of Aortic Aneurysm

Ming-Jay Chow, Jarred Raymund Mondonedo, and Katherine Yanhang Zhang

SBC2011-53729 67

Biomechanical and Microstructural Analysis of Wildtype (C57BL6) Mouse Aorta

Darren Haskett, Greg Johnson, Mohamad Azhar, and Jonathan Vande Geest

SBC2011-53873 69

Association of Mechanical Properties and Collagen Content With Valve Morphology in

Ascending Thoracic Aortic Aneurysmal Tissue

Joseph E. Pichamuthu, Julie A. Phillippi, Deborah A. Cleary, Douglas W. Chew,John Hempel, Thomas G. Gleason, and David A. Vorp

SBC2011-53947 71

Machine Learning Techniques for the Assessment of AAA Rupture Risk

Judy Shum, Elena S. Di Martino, Satish C. Muluk, and EnderA. Finol

BIOMECHANICS OF INJURY I

SBC2011-53001 73

Closed Joint Traumatic Impaction and Its Influence on Meniscal Cell Viability

Megan L. Killian, Roger C. Haut, and Tammy L. Haut Donahue

SBC2011 53082 75

The Duration of a Nerve Root Compression Modulates Evoked Neuronal Responses in a

Rat Model of Painful InjuryKristen J. Nicholson and Beth A. Winkelstein

viii

SBC2011-53136 77

Development of a Biofidelic Material Model for Brain Tissue

Sandeep Kulathu and David L. Littlefield

SBC2011-53152 79

Mechanism of Injury in a High Ankle Sprain: A Simulation StudyFeng Wei, Jerrod E. Braman, Eric G. Meyer, John W. Powell, and Roger C. Haut

SBC2011-53579 81

Emulating the Interfacial Kinematics of CNS White Matter With Finite Element TechniquesYi Pan, Assimina A. Pelegri, and David I. Shreiber

SBC2011-53586 83

The Effects of Apertures on Internal Pressure Measured During Shock Wave ExposureAlessandra Dal Cengio Leonardi, Cynthia Bir, Dave Ritzel, and Pamela VandeVord

BIOMECHANICS OF INJURY II

SBC2011-53247 85

The Computational Evaluation of a Locking Plate Fixation: Locking Versus

Far Cortical Screws

Mehran Moazen, Alison C. Jones, Jonathan Mak, Zhongmin Jin, Ruth K. Wilcox, and

Eleftherios Tsiridis

SBC2011-53265 87

Development and Validation of an In-Vivo Finite Element Pelvis Model With Cortical

Thickness Mapped From a Cadaver

Young Ho Kim, Jong-Eun Kim, and Alan Eberhardt

SBC2011-53296 89

Wrist Kinematics and Ultrasound Measures of the Median Nerve During Computer

KeyboardingKevin K. Toosi and Michael L. Boninger

SBC2011-53631 91

Wrapping of the Medial Ulnar Collateral LigamentAmin M. Motlagh and Mark Carl Miller

SBC2011-53660 93

The Effect of Return to Overuse Activity After a Supraspinatus Tear on Joint Function and

Biceps Mechanical Properties in a Rat Model

Stephen J. Thomas, Joseph J. Sarver, Jennica Tucker, Katherine Reuther, Lena Edelstein,Sarah Ilkhani-Pour, Chancellor Gray, Chang Soo Lee, David L. Glaser, and

Louis J. Soslowsky

SBC2011-54019 95

Near Side Lateral Impacts and Aortic Injury: A Parametric StudyAditya Belwadi and King H. Yang

ix

BIOMEMS AND MICROFLUIDICS

SBC2011-53093 97

Modulation of Oxygen Tensions via Microfabricated Devices

Shawn Oppegard and David Eddington

SBC2011-53529 99

Exponential Concentration Gradients in Microfluidic Devices for Cell Studies

Seila Selimovid, Woo Young Sim, Sang Bok Kim, Yun Ho Jang, Won Gu Lee,

Masoud Khabiry, Hojae Bae, Sachin Jambovane, Jong Wook Hong, and

AH Khademhosseini

SBC2011-53710 101

Wide Range Logarithmic Gradient Formation for Cell Response

Morgan Hamon, Kirn Cramer, Sachin Jambovane, Jing Dai, AH Khademhosseini, and

Jong Wook Hong

SBC2011-53839 103

A Microfluidic Mixer to Activate Sperm Cells of Aquatic Species for Standardization of

Computer-Assisted Motion AnalysisDaniel S. Park, Robert Egnatchik, Hali Bordelon, Terrance R. Tiersch, and

W. Todd Monroe

SBC2011-53995 105

Digital Microfluidic Platform for 3D Tissue Based High Throughput ScreeningSubin M. George and Hyejin Moon

SBC2011-54005 107

Design of Efficient Electroosmotic Micromixer

Yogendra M. Panta and Param C. Adhikari

BIO-THERMAL ENGINEERING

SBC2011-53388 109

Reflections on Quantitative Gamma Imaging of Cell-Surface Interactions

Robert C. Eberhart

SBC2011-53598 111

Monte Carlo Simulation of Enhanced Laser Absorption in Tumors With Gold

Nanorod Injection

Yonghui Chen, Ronghui Ma, and Liang Zhu

SBC2011-53814 113

Delineation of Noise Signals From MRI Measured Temperature Rise During HIFU

Ablation Procedure

Subhashish Dasgupta, Seyed Ahmed Reza Dibaji, Janaka Wansapura, Matthew R. Myers,and Rupak K. Banerjee

SBC2011-53853 115

Measurement and Analysis of Cutaneous Perfusion Depression During CryotherapySepideh Khoshnevis, Daniel W. Hensley, and Kenneth Diller

x

SBC2011-53933 117

Parameter Correlation in Models of Hyperthermic Cell Death

We/7 7. Wright

SBC2011-53950 119

Importance of Protein Denaturation to Thermochemical Ablation of Liver Tumors

Shoji Mori, Rajagopal Aravalti, Jeunghwan Choi, Erik Cressman, and John Bischof

BIOTRANSPORT EDUCATION

SBC2011-53011 121

Appropriate Technology in an Introductory Engineering Design ExperienceAlan W. Eberhardt, Richard J. Lesley, Tina G. Oliver, and Rosalia N. Scripa

SBC2011-53096 123

Biotransport Education: Thermal TherapiesJohn Pearce

SBC2011-53123 125

A Textbook and Other Resources for Teaching Challenge-Based BiotransportRobert J. Roselli and Kenneth R. Oilier

SBC2011-53149 127

Education Activities of Bioengineering for Undergraduate Students at IIMBC

Liang Zhu, Dwayne Arola, Charles Eggleton, and Anne Spence

SBC2011-53178 129

Biotransport: Fluid Mechanics, Heat and Mass Transfer

P. S. Ayyaswamy

SBC2011-53379 131

Teaching Experience in Biotransport Course for Undergraduates of Biomedical EngineeringLisa X. Xu and Aili Zhang

BIOTRANSPORT IN TISSUE AND CELLULAR ENGINEERING

SBC2011-53407 133

Effects of Freezing-Induced Cell-Fluid-Matrix Interactions on Cells and Extracellular Matrix

of Engineered Tissues

Ka Yaw Teo, J. Craig Dutton, Frederick Grinnell, and Bumsoo Han

SBC2011-53415 135

An Electromechanical Bioreactor for Scaffold-Free Skeletal Muscle Tissue Engineering

Ryan A. Koppes, Nathan R. Schiele, and David J. Corr

SBC2011-53490 137

Positive and Negative Wall Shear Stress Gradients Have Different Effects on Endothelial

Phenotype Under High Wall Shear Stress

Jennifer Dolan, Frasier Sim, Hui Meng, and John Kolega

SBC2011-53509 139

Functionalization of Electrospun Poly (Caprolactone) to Achieve Enhanced Cell Attachment

Manisha Jassal, Shawn M. Regis, and Sankha Bhowmick

xi

SBC2011-53910 141

Development of a 3D Microfluidic Culture Model to Study the Effect of Shear Stress on

Tumor AngiogenesisCara F. Buchanan, Elizabeth Voigt, Christopher S. Szot, Joseph W. Freeman,

Pavlos P. Vlachos, and M. Nichole Rylander

SBC2011-53955 143

Delivery of Active FGF-2 From Mechanically-Stable Biological Nanofibers Accelerates Cell

Ingress Into Multifiber Composites

Jonathan A. Kluge, Rudra A. Pampati, Mara L. Schenker, Daniel J. Zhou, John E. Esterhai,

David L Kaplan, and Robert L Mauck

CARDIAC MECHANICS

SBC2011-53071 145

A Theoretical Assessment of the Influence of Myosin Filament Dispersion on Smooth

Muscle Contraction

Martin Kroon

SBC2011-53117 147

Analysis of Infarct Size on Myocardial Infarction Remodeling

Pel Zhang, Tieluo Li, Katrina Williams, Shuyin Li, Xufeng Wei, Hosung Son,

Pablo Sanchez, Bartley P. Griffith, and Zhongjun J. Wu

SBC2011-53142 149

A Biventricular Finite Element Model of Heart Failure for Predicting the Effects of

Treatment StrategiesJonathan F. Wenk, Liang Ge, Zhihong Zhang, Mehrdad Soleimani, D. Dean Potter,

Arthur W. Wallace, Mark B. Ratcliffe, and Julius M. Guccione

SBC2011-53285 151

Incorporation of Perfusion Information Into a Finite Element Model of the Left Ventricle

A. I. Veress, G. T. Gullberg, W. P. Segars, B. M. W. Tsui, and G. S. K. Fung

SBC2011-53620 153

Regional Mechanical Anisotropy in Decellurized Rat Heart Ventricle

Colleen Witzenburg, Ramesh Raghupathy, Stefan M. Kren, Doris A. Taylor, andVictor H. Barocas

SBC2011-53956 155

A Structural Constitutive Model for Right Ventricular MyocardiumDaniela Valdez-Jasso, Marc A. Simon, and Michael S. Sacks

CARDIOVASCULAR DESIGN AND DEVICES I

SBC2011-53224 157

Effects of Knee Flexion on Stented Peripheral Arteries: A Computational and In-Vitro StudyRiona Nl Ghriallais and Mark Bruzzi

SBC2011-53316 159

Differences in Shear Stress, Residence Time and Estimates of Hemolysis Between Different

Ventricular Assist Devices

Katharine H. Fraser, Tao Zhang, Bartley P. Griffith, and Zhongjun J. Wu

xii

SBC2011-53380

Hemodynamic Performance of Oversized Flow Diverters

Fernando Mut and Juan R. Cebral

161

SBC2011-53420 163

Evaluation of Syncardia Total Artificial Heart Using Device Thrombogenicity Emulator

Yared Alemu, Gaurav Girdhar, Michalis Xenos, Thomas E. Claiborne, Jolyon Jesty,Shmuel Einav, Marvin Slepian, and Danny Bluestein

SBC2011-53468 165

Experimental Investigation of the Local Blood Flow Pattern in Stented Coronary Bifurcations

Stefano Morlacchi, Jaime Schmieg, Daniel Cooper, Francesco Burzotta,Francesco Migliavacca, and Pavlos P. Vlachos

SBC2011-53871 167

Modeling Arterial Wall Transport for Drug-Eluting Stents

Franz Bozsak, Jean-Marc Chomaz, Fulvio Martinelli, and Abdul I. Barakat

CARDIOVASCULAR DESIGN AND DEVICES II

SBC2011-53089 169

Assessment of Minimally Invasive Device That Provides Simultaneous Adjustable Cardiac

Support and Active Synchronous Assist in an Acute Heart Failure Model

Michael Moreno, Saurabh Biswas, Lewis D. Harrison, Guillaume Pernelle,Matthew W. Miller, Theresa W. Fossum, David A. Nelson, and John C. Criscione

SBC2011-53155 171

Localized Cooling Device for Myocardial Tissue SalvageJennifer E. Akers, Denise R. Merrill, Todd J. Nilsen, Kevin J. Koomalsingh,

Masahito J. Minakawa, Takashi Shuto, Joseph H. Gorman, III, Robert C. Gorman,Matthew J. Gillespie, and Thomas L. Merrill

SBC2011-53171 173

Design Optimization of Rotary Blood Pumps: Alternatives to Anticoagulation TherapyGaurav Girdhar, Michalis Xenos, Wei-Che Chiu, Yared Alemu, Bryan Lynch, Jolyon Jesty,

Marvin Slepian, Shmuel Einav, and Danny Bluestein

SBC2011-53172 175

Mechanical Flow Restoration in Acute Ischemic Stroke: A Model System of Cerebrovascular

Occlusion

J. Y. Chueh, A. K. Wakhloo, and M. J. Gounis

SBC2011-53891 177

Fluid Study of Transcatheter Aortic Valve Deployment Into Patients With Varying CoronaryOstia Position

Eric Sirois, Qian Wang, Susheel Kodali, and Wei Sun

SBC2011-53911 179

Radiofrequency Ablation With a Cryogenically Cooled Catheter to PercutaneouslyTreat Mitral Valve Prolapse

Steven M. Boronyak and W. David Merryman

xiii

CARDIOVASCULAR DIAGNOSTICS

SBC2011-53245 181

Assessment of Aortic Graft Impact on HemodynamicsOrestis Vardoulis, Eline Coppens, Bryn Martin, Philippe Reymond, and

Nikos Stergiopulos

SBC2011 -53367 183

A 1D Wave Propagation Model of Coronary Flow in a Beating Heart

Arjen van der Horst, Frits L Boogaard, Marcel C. M. Rutten, and Frans N. van de Vosse

SBC2011-53375 185

The Parameterized Diastolic Filling Formalism: Application in the Asklepios PopulationTom Claessens, Muhammad Waheed Raja, Antoine Pironet, Julio Chirinos,

Thomas Desaive, Ernst Rietzschel, Marc De Buyzere, Peter Van Ransbeeck,

Pascal Verdonck, Thierry Gillebert, and Patrick Segers

SBC2011-53642 187

Impedance to Cerebrospinal Fluid Flow in the Cervical Spinal Canal is Dominated byGeometric Complexity

Nicholas Shaffer, Francis Loth, Oliver Wieben, Brandon Rocque, Bermans Iskandar, and

John Oshinski

SBC2011-53769 189

Impact of Aortic Prosthetic Heart Valve Dysfunction on Left Ventricular Afterload and on the

Accuracy of Echo-Doppler Measurements

Othman Smadi, Zahra Keshavarz-Motamed, Ibrahim Hassan, Philippe Pibarot, and

Lyes Kadem

SBC2011-53965 191

Assessment of Right Ventricular Inefficiency Using Energy Transfer Ratio in Repaired

Tetralogy of Fallot

Namheon Lee, Ashish Das, William M. Gottliebson, and Rupak K. Banerjee

CARDIOVASCULAR TISSUE ENGINEERING

SBC2011-53120 193

The Potential of Prolonged Tissue Culture to Reduce Stress Generation and Retraction in

Engineered Heart Valve Tissues

Marijke A. A. van Vlimmeren, Anita Driessen-Mol, Cees W. J. Oomens, and

Frank P. T. Baaijens

SBC2011-53630 195

Anchorage: Dependent Persistent Alignment of Perfused Microvasculature in ImplantedTissue Constructs

Laxminarayanan Krishnan, Carlos C. Chang, Shawn Reese, Stuart K. Williams,

Jeffrey A. Weiss, and James B. Hoying

SBC2011-53689 197

Optimzing a Three Layered Electrospun Matrix to Mimic Native Arterial Architecture:

Cellular and Mechanical AnalysisMichael J. McClure, Scott A. Sell, David G. Simpson, Beat H. Walpoth, and Gary L Bowlin

xiv

SBC2011-53761 199

Self-Assembling Peptide Nanofibers for MMP Delivery and Cardiac Regenerationin Diabetes

Jennifer R. Hurley, Abdul Q. Sheikh, Meredith Beckenhaupt, Cameron Ingram,Andrew Mutchler, and Daria A. Narmoneva

SBC2011-53797 201

Diabetes Alters Intracellular Calcium Transients in Cardiac Endothelial Cells

Abdul Q. Sheikh, Jennifer R. Hurley, and Daria A. Narmoneva

SBC2011-53967 203

A Strain Energy-Based Constitutive Model for Continuous-Fiber Tissue Engineered Valved

Conduit Tissue

Chad E. Eckert and Michael S. Sacks

CARTILAGE/DISC MECHANICS

SBC2011-53173 205

A Comparison of the Mechanical Properties of the Goat Temporomandibular Joint Disc

to the Mandibular Condylar Cartilage in Unconfined CompressionCatherine K. Hagandora and Alejandro J. Almarza

SBC2011-53436 207

Magnetic Resonance Elastography for the Measurement of Annulus Fibrosus Material

PropertiesDaniel H. Cortes, Lachlan J. Smith, Sung M. Moon, Jeremy F. Magland,

Alexander C. Wright, and Dawn M. Elliott

SBC2011-53477 209

Finite Element Implementation of Neutral Solute Transport in Porous BiologicalSoft Tissues Under Finite Deformation

Gerard A. Ateshian, Michael B. Albro, Steve Maas, and Jeffrey A. Weiss

SBC2011-53496 211

Local Shear Deformation in Whole Cartilage Explants Determined by Texture Correlation

Jonathan T. Henderson, Garrett Shannon, Kai Yuen, and Corey P. Neu

SBC2011-53718 213

Evaluation of Wrist Cartilage With and Without Scapholunate Ligament Injury in Pre and

Post Operation SubjectsDannica L. Sturgeon, Sang-Pil Lee, Terence E. Mclff, E. Bruce Toby, and

Kenneth J. Fischer

SBC2011-53913 215

Detection of MMP-13 Activity on Intentionally Strain-Released Type-ll Collagen Network in

Bovine Articular CartilageNazli Caner and Jeffrey W. Ruberti

CFD MODELING AND APPLICATIONS

SBC2011-53441 217

Hemodynamic Compromise During Carotid Angioplasty and StentingA. G. Lynch and M. T. Walsh

xv

SBC2011-53602 219

Framework for Fluid-Structure Interaction Analysis of Aortic Coarctation Resulting From

Proximal Protusion of Thoracic Aortic Stent Graft Into the Arch

Salvatore Pasta, Onur Dur, Jae-Sung Cho, Kerem Pekkan, and David A. Vorp

SBC2011-53879 221

Smoothed Particle Hydrodynamics Simulation of Flow Through a Bileaflet

Mechanical Heart Valve: Advantages and ProspectsShahrokh Shahriari, Hoda Maleki, Ibrahim Hassan, and Lyes Kadem

SBC2011-53886 223

Nitric Oxide Transport in Lymphatic Vessels

John T. Wilson, Rebecca L Dahlin, Olga Gasheva, David C. Zawieja, and

James E. Moore, Jr.

SBC2011-53890 225

Pulsatile Hemodynamics of the Fontan Connection: ATri-Modal Investigation

Christopher M. Haggerty, Diane A. de Zelicourt, Jessica R. Kanter,

KartikS. Sundareswaran, Mark A. Fogel, and AjitP. Yoganathan

GRAND CHALLENGE COMPETITION TO PREDICT IN VIVO KNEE LOADS

SBC2011-53594 227

A Weighted Objective Function Reduces Estimates of Medial and Lateral Knee Joint

Contact Loads During Gait

S. C. E. Brandon, D. G. Thelen, and K. J. Deluzio

SBC2011-53650 229

Introduction of Contact Forces Minimization in the Musculo-Tendon Forces OptimizationDuring Gait

Florent Moissenet, Laurence Cheze, and Raphael Dumas

SBC2011-53940 231

A Musculoskeletal Model With Prosthetic Knee During a Walk CycleMohammad Kia and Trent M. Guess

SBC2011-53948 233

Dual-Joint Modeling for Estimation of Total Knee Replacement Contact Forces DuringLocomotion

Michael W. Hast and Stephen J. Piazza

HEAT VALVE MECHANOBIOLOGY

SBC2011-53315 235

Discovery of Side- and Shear-Dependent miRNAs and mRNAs in Human Aortic Valvular

Endothelial Cells

Casey J. Holliday, Randall F. Ankeny, Hanjoong Jo, and Robert M. Nerem

SBC2011-53637 237

Physiological Micromechanics of the Anterior Mitral Valve Leaflet

Christopher A. Carruthers, Bryan Good, Antonio D'Amore, Rouzbeh Amini,Joseph H. Gorman, and Michael S. Sacks

xvi

SBC2011-53668 239

Evaluation of Acellular Mitral Valve Scaffolds: Anterior Leaflet, Posterior Leaflet, and

Chordae Tendineae

Bo Wang, Dustin McCallum, Lakiesha Williams, and Jun Liao

SBC2011-53791 241

Biomechanical Analysis of Embryonic Atrioventricular ValvulogenesisPhilip R. Buskohl, Russell A. Gould, and Jonathan T. Butcher

SBC2011-53899 243

Calcific Nodule Morphogenesis by Aortic Valve Interstitial Cells: Synergism of AppliedStrain and TGF-G1

Joseph Chen, Charles I. Fisher, M. K. Sewell-Loftin, and W. David Merryman

SBC2011-53946 245

Low and Unsteady Shear Stresses Upregulate Calcification Response of the

Aortic Valve Leaflets

Swetha Rathan, Choon Hwai Yap, Elizabeth Morris, Sivakkumar Arjunon, Hanjoong Jo,and Ajit P. Yoganathan

HEART VALVES: LEAFLET AND ANNULUS MECHANICS

SBC2011-53088 247

Tricuspid Valve Annulus Tension

Shamik Bhattacharya and Zhaoming He

SBC2011-53195 249

In-Vivo Dynamic Strains of the Ovine Anterior Mitral Valve Leaflet

Manuel Rausch, Wolfgang Bothe, John-Peder Escobar-Kvitting, Serdar Goktepe,Craig Miller, and Ellen Kuhl

SBC2011-53487 251

Effect of Aortic Distensibility on Coronary Flow: A 3D FSI Model of Aortic Valve With the

Inclusion of Coronary Arteries

Soroush Nobari, Rosaire Mongrain, Richard Leask, and Raymond Cartier

SBC2011-53842 253

Simulations of Flow Through Bileaflet Mechanical Heart Valves to Assess Platelet DamageB. Min Yun, Jingshu Wu, Cyrus K. Aidun, and Ajit P. Yoganathan

SBC2011-53851 255

Simulated Deployment of Percutaneous Transvenous Mitral Annuloplasty Device Into

Human Coronary Sinus Vessel

Thuy M. Pham, Qian Wang, Milton DeHerrera, and Wei Sun

SBC2011-53925 257

Functional Dynamic In-Vivo Stresses of the Mitral Valve Anterior Leaflet

Rouzbeh Amini, Chad E. Eckert, Christopher A. Carruthers, Kevin Koomalsingh,Mashito Minakawa, Robert C. Gorman, Joseph H. Gorman, III, and Michael S. Sacks

xvii

HEMODYNAMICS OF ANEURYSMS

SBC2011-53306 259

Direct Numerical Simulation of Transitional Flow in a Patient-Specific MCA Aneurysm

Kristian Valen-Sendstad, Kent-Andre Mardal, Mikael Mortensen, Bj0rn A. P. Reif, and

Hans Fetter Langtangen

SBC2011-53382 261

Longitudinal Image Based Study of Cerebral Aneurysms: Growth, Contacts and

Hemodynamics During Aneurysmal Progression

Juan R. Cebral, Daniel Sforza, Satoshi Tateshima, Fernando Vinuela, and

Christopher Putman

SBC2011-53503 263

Steady Versus Pulsatile Flow Modeling for Hemodynamics Based Stratification of a

Population of Intracranial AneurysmsRohini Retarekar, Benjamin Berkowitz, and Madhavan L. Raghavan

SBC2011-53723 265

An Experimental Study of the Effects Anatomical Variations Have on Collateral Flows

Within the Circle of Willis

Paul Fahy, Patrick Delassus, Padraig O'Flynn, and Liam Morris

SBC2011-53819 267

Hemodynamics of Elastase-lnduced Aneurysms in Rabbit:

A New High Flow Bifurcation Model

Zijing Zeng, David F. Kallmes, Yong Hong Ding, Ramanathan Kadirvel, Debra A. Lewis,D. Dai, and Anne M, Robertson

SBC2011-53864 269

Comparison of Normal and Pathological Hemodynamics in Coronary Artery AneurysmsCaused by Kawasaki Disease

Dibyendu Sengupta, Jane C. Burns, Andrew Kahn, and Alison L. Marsden

HUMAN DYNAMICS

SBC2011-53193 271

Neck Muscle Strength Measured During Vigorous Head ShakingJames Funk, Richard Watson, Joseph Cormier, Charles Bain, Herb Guzman, and

Enrique Bonugli

SBC2011-53453 273

Improved Simulation of Heel Contact During Normal WalkingArash Mahboobin, Rakie Cham, and Stephen J. Piazza

SBC2011-53458 275

A Robust Real-Time Control Algorithm for Whole-Body RunningXianlian Zhou and Andrzej Przekwas

SBC2011-53475 277

A Surface-to-Surface Contact Model for Multibody Dynamics Modelling of the Human HipAdam Stops, Ruth Wilcox, and Zhongmin Jin

xviii

SBC2011-53697 279

Dynamic Trunk Control Influence on Run-to-Cut Maneuver: A Risk Factor for ACL RuptureSteve T. Jamison, Xueliang Pan, and Ajit M. W. Chaudhari

SBC2011-53973 281

A Spring-Mass Model of Locomotion With Full Asymptotic StabilityZhuohua Shen and Justin Seipel

MATERIAL AND STRUCTURAL CHARACTERIZATION OF BONE

SBC2011-53103 283

Functional Imaging of the Proximal Femur Using Shape Template and a Bone Mineral

Density ImageSami P. Vaananen, Hanna Isaksson, and Jukka S. Jurvelin

SBC2011-53320 285

Creep Simulation of a Micro-CT Based Finite Element Model of Porcine Cancellous Bone

Ahmet H. Ertas, Betty J. Sindelar, and John R. Cotton

SBC2011-53351 287

Indentation Simulation of Ovariectomized Sheep Bone Using a Viscoelastic/Plastic

Damage Model

Yang Zhao and Timothy C. Ovaert

SBC2011-53698 289

Cervical Spine Bone Mineral Density as a Function of Vertebral Level and Anatomic Location

Eric Thorhauer, William Anderst, William Donaldson, Joon Lee, and James Kang

SBC2011-53768 291

The Effects of a Functionally Graded Cellular Structure on Impact Properties of a Hip Joint:

A Finite Element StudyT. Kara, S. Takak, M. AH, and J. Hoffman

SBC2011-53927 293

Shear Strain of Mineral Crystals Calculated Using Wide-Angle X-Ray Scattering (WAXS)Techniques

Bijay Giri, X. Neil Dong, Jon D. Aimer, and Xiaodu Wang

MECHANICAL CIRCULATORY SUPPORT

SBC2011-53207 295

A Particle Image Velocimetry Study of the Penn State 50cc Left Ventricular Assist Device:

The Impact of Varying Heart Rate

Michael A. Navitsky, Jason C. Nanna, Stephen R. Topper, Steven Deutsch, and

Keefe B. Manning

SBC2011-53241 297

In Silico Design and In-Vivo Analysis of the Pediaflow Pediatric Ventricular Assist Device

Timothy M. Maul, James F. Antaki, Jingchun Wu, Jeongho Kim, Marina V. Kameneva,Salim E. Olia, Peter D. Wearden, Ergin Kocyildirim, and Harvey S. Borovetz

xix

SBC2011-53585 299

Development, Pre-Clinical Validation of the UltraMag and Summary of the Clinical

Experience With Levitronix Ventricular Assist SystemBarry N. Gellman, J. Scott Richardson, Egemen Tuzun, Thomas M. Gempp,

Kelly M. Harms, Andreas Fleischli, Kimberly S. Moody, John D. Marks, JeffL. Conger,Stella Kent, 0. Howard Frazier, and Kurt A. Dasse

SBC2011-53644 301

Multi-Laboratory Uncertainty Analysis of PIV-Measured Flow Quantities Relevant to Blood

Damage in the FDA Nozzle Model

Prasanna Hariharan, Matthew Giarra, Varun Reddy, Steven W. Day, Keefe B. Manning,Steven Deutsch, Matthew R. Myers, Sandy F. C. Stewart, Greg W. Burgreen,

Eric G. Paterson, and Richard A. Malinauskas

SBC2011-53699 303

Novel Extra Aortic Counterpulsation Device for Enhancing Cardiac Performance

Peter W. Walsh, Craig McLachlan, Leigh Ladd, and R. Mark Gillies

SBC2011-53735 305

Assessment of Cardiac Function During Mechanical Circulatory Support:A Simulation Study

Antonio Ferreira, Yajuan Wang, John Gorcsan, III, and James F. Antaki

MECHANOREGULATION OF BONE: A TRIBUTE TO RIK HUISKES

SBC2011-53473 307

Progressive Subchondral Sclerosis During OA Explained by Depth-Dependent Bone

Demineralization

L. G. E. Cox, B. van Rietbergen, C. C. van Donkelaar, and K. Ito

SBC2011-53485 309

Altered Mechanosensitivity Can Explain the Substantially Increased Bone Mass in

HypoparathyroidismPatrik Christen, Bert van Rietbergen, and Keita Ito

SBC2011-53714 311

Simulation of the Emergence of the Endochondral Ossification Process in Evolution

Hanifeh Khayyeri and Patrick J. Prendergast

SBC2011-53773 313

Bone Biomechanical Behavior in Adult Mice is Regulated by Osteoblast Gi Signaling in a

Sex- and Site-Specific MannerAaron J. Fields, Susan M. Millard, Jeannie F. Bailey, Dylan O'Carroll, Jeffrey C. Lotz, and

Robert A. Nissenson

SBC2011-53803 315Shear Stress Within Trabecular Bone Marrow due to Low Magnitude HighFrequency Vibration

Thomas R. Coughlin, Laoise M. McNamara, Peter E. McHugh, and Glen L. Niebur

xx

SBC2011-54015 317

Induced Intramedullary Pressure by Dynamic Hydraulic Stimulation and Its Potential in

Attenuation of Bone Loss

M. Hu, J. Cheng, S. Ferreri, F. Serra-Hsu, W. Lin, and Y. X. Qin

MECHANOTRANSDUCTION AND SUB-CELLULAR BIOPHYSICS I

SBC2011-53264 319

In Situ Observation of Nuclear Behavior During Laser Nano-Dissection of Actin Stress Fibers:

Mechanical Interaction Between Actin Stress Fibers and Nucleus

Kazuaki Nagayama, Yuki Yahiro, and Takeo Matsumoto

SBC2011-53294 321

The Roles of HS and Its Glypican-1 Core Protein in Flow-Induced Endothelial NOS

Activation and Cell RemodelingE. E. Ebong, D. C. Spray, and J. M. Tarbell

SBC2011-53432 323

Differentiation and Dynamic Tensile Loading Alter Nuclear Mechanics and

Mechanoreception in Mesenchymal Stem Cells

Su-Jin Heo, Nandan L. Nerurkar, Tristan P. Driscoll, and Robert L Mauck

SBC2011-53709 325

Engineering Tools for Studying Coordination Between Biochemical and Biomechanical

Activities in Cell Migration

Sungsoo Na

SBC2011-53757 327

A Multiscale Model of Cell Adhesion and Migration on Extracellular Matrices of Defined

Stiffness and AdhesivityAmit Pathak and Sanjay Kumar

SBC2011-54027 329

Dynamics of Membrane Rafts, Talin, and Actin at Nascent and Mechanically Perturbed

Focal Adhesions

Daniela E. Fuentes and Peter J. Butler

MECHANOTRANSDUCTION AND SUB-CELLULAR BIOPHYSICS II

SBC2011-53435 331

Oscillatory Fluid Flow Affects the Osteogenic Differentiation of Human Bone Marrow

Stromal Cells in a Primary Cilium Dependent MannerDavid A. Hoey and Christopher R. Jacobs

SBC2011-53446 333

Mechanically Induced Calcium Release From Bone Matrix Triggers Intracellular Ca2+

Signalling in Osteoblasts: A Novel Mechanotransduction Mechanism

Xuanhao Sun, Vipuil Kishore, Kateri Fites, and Ozan Akkus

xxi

SBC2011-53600 335

Remodeling and Contractility of the Actin Cytoskeleton During the Shear Deformation of

Single ChondrocytesEnda P. Dowling, William Ronan, Vikram S. Deshpande, Robert M. McMeeking,

Kyriacos A. Athanasiou, and J. Patrick McGarry

SBC2011-53604 337

The Role of SRC in Strain- and Ligand- Dependent Phenotypic Modulation of Mouse

Embryonic Fibroblasts

M. K. Sewell-Loftin and W. David Merryman

SBC2011-53811 339

How Do Cells Sense Substrate Stiffness? Effects of Substrate Elasticity and Thickness on the

Behavior of Rat Aortic Smooth Muscle Cells

Takeo Matsumoto, Norihiro Matsui, Mai Ishiguro, and Kazuaki Nagayama

SBC2011-53924 341

Cyclic Strain and Interstitial Flow Modulate Cardiac Fibroblast Phenotype ThroughAngiotensin II and TGF-IS Pathways

Peter A. Galie and Jan P. Stegemann

MECHANOTRANSDUCTION AND SUB-CELLULAR BIOPHYSICS III

SBC2011-53057 343

Adipocytes Respond to Mechanical Stretch by Producing More LipidsNaama Shimon, Orna Shaharabani-Yosef, Uri Zaretsky, and Amit Gefen

SBC2011-53062 345

Both Hypoglycemia and Hyperglycemia Prevent Endothelial Cell Actin Fiber Alignment to

Fluid Shear Stress

Steven F. Kemeny and Alisa Morss Clyne

SBC2011-53266 347

What Forces Does Cell Traction Force Microscopy Measure?

Evan A. Zamir

SBC2011-53308 349

Magnetoelastic Materials as Novel Bioactive Coatings to Improve Integration of

Percutaneous ImplantsHal Holmes, Eli Vlaisavljevich, Ee Lim Tan, Keat G. Ong, and Rupak M. Rajachar

SBC2011-53317 351

Effect of ST2, a Fragment of ADAMTS13, on Cleavage of Von Willebrand Factor

Jin-Yu Shao, Yingchen Ling, J. Evan Sadler, and Elaine M. Majerus

SBC2011-53741 353

Compression Force Measurement During Cell Spreading Using a Modified Atomic

Force MicroscopePaul Weafer, Maarten H. van Es, Suzanne P. Jarvis, and Patrick J. McGarry

xxii

MODEL SYSTEMS AND THE PERICELLULAR ENVIRONMENT

SBC2011-53070 355

A Method for Quantitative Analysis of the Kinematics of Fibroblast Migration in a

Monolayer Wound Model

Gil Topman, Orna Sharabani-Yosef, and Amit Gefen

SBC2011-53251 357

Fibroblast Behavior on Tunable Gels With Decreasing ElasticityMichelle L Previtera, Kevin L. Trout, Uday Chippada, Rene Schloss, and

NoshirA. Langrana

SBC2011-53648 359

In-Vitro Model of the Microscale Alveolar Environment

Natalia Higuita-Castro, Cosmin Mihai, Derek J. Hansford, and Samir N. Ghadiali

SBC2011-53721 361

Non-Destructive Real-Time Imaging of Cell Seeded Tissue Engineered Scaffolds

Bryce M. Whited, Matthias C. Hofmann, Chris G. Rylander, Aaron S. Goldstein,

Joseph W. Freeman, Mark Furth, Shay Soker, Ge Wang, Yong Xu, and

Marissa N. Rylander

SBC2011-53732 363

Changes in Biomechanical Environment of Cardiac Cells in Chick Embryos After

Cardiac Outflow Tract BandingAiping Liu, Kent Thornburg, Ruikang Wang, and Sandra Rugonyi

SBC2011-53767 365

The Mechanical and Biochemical Environment Controls Cellular Differentiation DuringMuscle Regeneration

Sarah Calve and Hans-Georg Simon

MULTISCALE MODELING IN BIOTRANSPORT

SBC2011-53033 367

A Hybrid Particle-Cell Model for Nanoparticle Targeted Delivery in Microcirculation

Yaling Liu, Jifu Tan, and Antony Thomas

SBC2011-53444 369

Voxelized 3D Computational Transport Model of Infusions Into the Ventral Hippocampus:Comparison With Experimental Studies

Jung Hwan Kim, Garrett Astary, Svetlana Kantorovich, Thomas H. Mareci, Paul R. Carney,and Malisa Sarntinoranont

SBC2011-53834 371

Modelling of Magnetic Targeting of Therapeutic Nanoparticles in a Two Phase

Microvessel Flow

Tobias Ecker and Christopher G. Rylander

SBC2011-53889 373

Parametric Investigation of Magnetic Particle Transport for Targeted Drug DeliveryApplications

Daniel B. Cooper and Pavlos P. Vlachos

xxiii

SBC2011-53976

Assessment of the Outflow Path Resistance of the Aqueous Humor Flow in the EyeSumanta Acharya and Jyoti Kathawate

375

SBC2011-53984 377

Computational Models and Digital Image Analysis of Carbon Nanotube Mediated

Laser Cancer TherapyJon Whitney, Ravi Singh, Marissa Nichole Rylander, Saugata Sarkar, Andrew Burke,

Xuanfeng Ding, and Suzy Torti

MUSCULOSKELETAL DESIGN AND DEVICES

SBC2011-53199 379

Comparison of Interface Stresses and Strains for Onlay and Inlay UnicompartmentalTibial Components

Peter S. Walker, Dhiraj S. Parakh, Miriam E. Chaudhary, and Chih-Shing Wei

SBC2011-53244 381

Automated Virtual Placement and Evaluation of Tibial Components for Knee Arthroplasty

Yifei Dai, Mary S. S. Wentorf, and Jeffrey E. Bischoff

SBC2011-53405 383

Numerical Reduction of Position Error in a Mechanical Tracking Linkage for Arthroscopic

Hip SurgeryEmily Geist and Kenji Shimada

SBC2011-53408 385

Design From Nature: Kinematic Modeling of the Seahorse Tail

Tomas Praet, Dominique Adriaens, Thibaut Rommens, Bert Masschaele,

Sofie Van Cauter, Matthieu De Beule, and Benedict Verhegghe

SBC2011-53881 387

Validation of an MRI-Based Method to Measure Tibiofemoral Joint Cartilage Contact Area

Jerome Allen, Venkata Gade, and Peter J. Barrance

SBC2011-53938 389

Evaluation of Regression Equations for Medial and Lateral Contact Force From Instrumented

Knee Implant Data

Andrew J. Meyer, Darryl D. D'Lima, Scott A. Banks, James Coburn, Melinda Harman,Yoshinori Mikashima, and Benjamin J. Fregly

MUSCULOSKELETAL TISSUE ENGINEERING

SBC2011-53130 391

Mechanical Stimulation Provides the Key Induction Signal for Tenogenic Differentiation of

Human Mesenchymal Stem Cells in Braided Nanofibrous Scaffolds

Andrew M. Handorf, John G. Barber, Tyler J. Allee, Ray Vanderby, and Wan-Ju Li

SBC2011-53442 393

Dynamic Culture Improves Mechanical Functionality of MSC-Laden Tissue EngineeredConstructs in a Depth-Dependent Manner

Megan J. Farrell, Eric S. Comeau, and Robert L. Mauck

xxiv

SBC2011-53589 395

Muscle Injury Attenuates BMP-2 Mediated Tissue Regeneration in a Novel Rat Model of

Composite Bone and Muscle InjuryNick J. Willett, M. Alice Li, Brent A. Unrig, Gordon L Warren, and Robert E. Guldberg

SBC2011-53601 397

Characterization of aGal(-) ECM Bioscaffolds: An Indication for Application in

Tissue EngineeringRui Liang, Matthew B. Fisher, Guoguang Yang, Christine Hall, and Savio L.-Y. Woo

SBC2011-53634 399

The Effect of Cyclic Hydrostatic Pressure on the Functional Development of CartilaginousTissues Engineered Using Bone Marrow Derived Mesenchymal Stem Cells

Eric G. Meyer, Conor T. Buckley, and Daniel J. Kelly

SBC2011-53674 401

Effects of Passaging on the Migration Response of Synovium-Derived Stem Cells

to an Applied DC Electric Field

Andrea R. Tan, Elena Alegre-Aguaron, Divya N. Dujari, Sonal R. Sampat,

J. Chloe Bulinski, Gerard A. Ateshian, and Clark T. Hung

NANO, MICRO AND MULTISCALE MECHANICS I

SBC2011-53352 403

In Silico Molecular Modeling of Collagen Crosslink Loading

Jonathan W. Bourne and Peter A. Torzilli

SBC2011-53511 405

Multi-Scale Modeling of Cancer Cell Migration and Adhesion During

Epithelial-to-Mesenchymal Transition

Rachel Zielinski, Cosmin Mihai, and Samir N. Ghadiali

SBC2011-53615 407

Flexural Rigidity of Intact Chlamydomonas Flagella Measured With an Optical Trap

R. J. Okamoto, J. Ying, B. L. Lewis, E. C. Ranz, J.-Y. Shao, S. K. Dutcher, and

P. V. Bayly

SBC2011-53809 409

A Combined In Vitro and In Silico Approach to Estimate the Molecular Arrangement

Within a Fibronectin Fiber

Mark J. Bradshaw and Michael L. Smith

SBC2011-53826 411

Influence of Zona Pellucida Area Expansion Stiffness on the Passive Response of

Oocytes to Osmotic LoadingSevan R. Oungoulian, Kelvin Chan, Jason Barritt, Casey A. McDonald,

Alan B. Copperman, David Elad, and Gerard A. Ateshian

SBC2011-53896 413

On the Mechanics of Microtubule Filaments

Mehrdad Mehrbod and Mohammad R. K. Mofrad

xxv

NANO, MICRO AND MULTISCALE MECHANICS II

SBC2011-53095 415

A Novel Nanoindentation Method for Hydrated Compliant Materials

Donna M. Ebenstein

SBC2011-53116 417

A von Mises Mixture to Describe Experimentally-Derived Fiber Distributions From

Soft Tissues

C. Ross Ethier, Cecile M. Gouget, and Michael J. Girard

SBC2011-53272 419

Modeling the Effect of the Experimentally-Derived Collagen Structure on the Mechanical

Anisotropy of the Human Sclera

Baptiste Coudrillier, Craig Boote, and Thao D. Nguyen

SBC2011-53336 421

Controlling Swimming Magnetotactic Bacteria Through Microfabrication Toward a

Non-Destructive Biological Sensor

Lina M. Gonzalez, Warren C. Ruder, Eli Zenkov, Philip R. LeDuc, and William C. Messner

SBC2011-53749 423

A Pipeline for High Throughput Post-Processing of Joint and Tissue Simulations for

Estimation of Cell Level Deformations

Scott Sibole and Ahmet Erdemir

SBC2011-53781 425

Multiscale Mechanical Models for Understanding Microstructural Damage in

Fibrous Tissues

Edward A. Sander, Mohammad F. Hadi, and Victor H. Barocas

OCULAR AND OTHER SOLID MECHANICS

SBC2011-53073 427

Mechanics of the Cephalopod Chromatophore Layer: Structural Characterization of

Cephalopod ChromatophoresKeith M. Kirkwood, George Bell, Alan M. Kuzirian, Roger T. Hanlon, and Eric D. Wetzel

SBC2011-53181 429

Modeling the Inflation Response of C57BL/6 Mouse Sclera

Kristin M. Myers and Thao D. Nguyen

SBC2011-53208 431

The Effect of Synthetic Ice Blockers on Thermal Expansion of the CryoprotectiveCocktail DP6

David P. Eisenberg and Yoed Rabin

SBC2011-53726 433

Ultrasonic Speckle Tracking for Measurement of Scleral Cross-Sectional Strains due to

Intraocular Pressure Elevation

J. Tang and J. Liu

xxvi

SBC2011-53745 435

Quantitative Measurements of Pressure Dependent Laminar Cribrosa Microstructure in

Human Eyes

Dongmei Yan, Joseph T. Keyes, and Jonathan P. Vande Geest

SBC2011-53849 437

Determination of Mechanical Stresses in Vibration and Contact DuringFlow-Structure-Interaction in Vocal Folds

Pinaki Bhattacharya and Thomas H. Siegmund

PhD STUDENT PAPER COMPETITION: BIOMATERIALS AND

NANOTECHNOLOGY

SBC2011-53128 439

Temperature Elevations in Implanted Prostatic Tumors in Mice During Magnetic

Nanoparticle Hyperthermia: In Vivo Experimental StudyAnilchandra Attaluri, Ronghui Ma, and Liang Zhu

SBC2011-53309 441

Characterizing the Ex-Vivo Mechanical Properties and Corresponding In-Vivo Impact of

Synthetic Urogynecological Meshes

Andrew J. Feola, Pamela Moalli, Suzan Stein, Zegbeh Jallah, Jon Shepherd, and

Steven D. Abramowitch

SBC2011-53324 443

Effect of Surface Charge on Gold Nanoparticle Biotransport: An In Vivo Blood and

Biodistribution StudyNeha B. Shah and John C. Bischof

SBC2011-53517 445

Controlled Release and Intracellular Delivery of Small Molecules Using Thermally

Responsive Pluronic F127-Chitosan NanocapsulesWujie Zhang, Kyle Gilstrap, Laying Wu, Melissa A. Moss, Qian Wang, Xiongbin Lu, and

Xiaoming He

SBC2011-53627 447

A Bioactive Peptide Grafted Scaffold for Peripheral Nerve Regeneration

Shirley Masand, Jian Chen, Melitta Schachner, and David I. Shreiber

SBC2011-53686 449

Fabrication, Characterization, and Bioactivity of Multi-Compartment Collagen-GAG

Scaffolds for Orthopedic Interfaces

Daniel Weisgerber, Steven Caliari, Emily Gonnerman, Rebecca Yapp, Michael Insana,

and Brendan Harley

PhD STUDENT PAPER COMPETITION: CARDIOVASCULAR FLOW

SBC2011-53389 451

Multiscale Modeling of the Blood Circulation in the Human Liver Using Vascular Corrosion

Casting and Micro-CT Imaging TechniquesCharlotte Debbaut, Diethard Monbaliu, Christophe Casteleyn, Pieter Cornillie,

Denis Van Loo, Luc Van Hoorebeke, Paul Simoens, Jacques Pirenne, and Patrick Segers

xxvii

SBC2011-53452 453

A Quantitative Comparison Between Baseline Hemodynamics and End-Stage AneurysmFormation in ApoE -/- Mice

Bram Trachet, Marjolijn Renard, Gianluca De Santis, Steven Staelens, Julie De Backer,

Luca Antiga, Bart Loeys, and Patrick Segers

SBC2011-53534 455

Hemodynamic Comparisons Between Different Anastomotic Configurations in

Dialysis Access Fistulae

Patrick M. McGah, Daniel F. Leotta, Kirk W. Beach, Alberto Aliseda, and James J. Riley

SBC2011-53541 457

A Longitudinal Assessment of Wall Shear Stress Variation on Arteriovenous

Fistula Maturation

Ehsan Rajabi Jaghargh, Prabir Roy-Chaudhury, Paul Succop, and Rupak K. Banerjee

SBC2011-53712 459

Size Ratio of Intracranial Aneurysms Predicts Rupture-Prone Hemodynamics

Jianping Xiang, Adnan Siddiqui, Sabareesh K. Natarajan, and Hui Meng

SBC2011-53752 461

Customization of the Fontan Y-Graft: Are Unequal Branches Necessary for Optimal HepaticFlow Distribution?

Weiguang Yang, Jeffrey A. Feinstein, Irene E. Vignon-Clementel, Shawn C. Shadden, and

Alison L Marsden

PhD STUDENT PAPER COMPETITION: CELL MECHANICS AND SIGNALING

SBC2011-53406 463

Basement Membrane Collagen Glycation Prevents Endothelial Cell Response to Strain

due to Altered Focal Adhesion Formation

Dannielle Solomon Figueroa and Alisa Morss Clyne

SBC2011-53417 465

Insights Into the Molecular Mechanisms of Actin Dynamics:A Multiscale Modeling Approach

Tamara C. Bidone, Marco A. Deriu, Giacomo Di Benedetto, Diana Massai, and

Umberto Morbiducci

SBC2011-53464 467

Stretch-Induced Stress Fiber Remodeling and MAPK Activations Depend on Mechanical

Strain Rate

Hui-Ju Hsu, Andrea Locke, Susan Q. Vanderzyl, and Roland Kaunas

SBC2011-53878 469

Simulation of Stress Fiber Remodeling and Mixed-Mode Focal Adhesion Assembly

During Cell Spreading and for Cells Adhered to Elastic Substrates

William Ronan, Vikram S. Deshpande, Robert M. McMeeking, and J. Patrick McGarry

SBC2011-53954 471

Dynamics of Stretch-Induced Stress Fiber Remodeling in 3D Cell Culture

Sheng-Lin Lee, AH Nekouzadeh, Kenneth M. Pryse, Elliot L. Elson, and Guy M. Genin

xxviii

SBC2011-54016

Cellular Response to Stretch by Modulation of Cytoskeletal Tension in Two Distinct Phases

Jennifer Mann, RaymondLam, and Jianping Fu

473

PhD STUDENT PAPER COMPETITION: MICRODEVICES AND

BIOTRANSPORT

SBC2011-53414 475

Simulating Diffuse Axonal Injury During Traumatic Brain Injury Events

Jean-Pierre Dolle, Rene Schloss, and Martin L Yarmush

SBC2011-53513 477

Functional Diagnosis of Coronary Artery Stenoses Using Pressure Drop Coefficient:

A Pilot Study in Humans

Kranthi K. Kolli, Mohamed Effat, Imran Arif, Tarek Helmy, Massoud Leesar, Lloyd H. Back,

and Rupak K. Banerjee

SBC2011-53569 479

What is the Pumping Mechanism Behind Embryonic Hearts?

Frederic Maes, Bill Chaudhry, Peter Van Ransbeeck, and Pascal Verdonck

SBC2011-53626 481

High Frequency Electroporation for Cancer Therapy

Christopher B. Arena, Michael B. Sano, Marissa Nichole Rylander, and Rafael V. Davalos

SBC2011-53828 483

A White Blood Cell Capturing Biochip Using a 3D Trapping Architecture

Anurag Tripathi and Nikos Chronis

SBC2011-53929 485

A Novel In Vitro Model for Irreversible Electroporation Based Cancer Therapies and

Treatment PlanningChristopher S. Szot, Christopher B. Arena, Paulo A. Garcia, Rafael V. Davalos,

Joseph W. Freeman, and Marissa Nichole Rylander

PhD STUDENT PAPER COMPETITION: ORTHOPAEDIC BIOMECHANICS

SBC2011-53395 487

Determination of In Vivo Ankle Ligament Strains During External Rotation of the Foot

Feng Wei, Jerrod E. Braman, Brian J. Weaver, and Roger C. Haut

SBC2011-53455 489

Feasibility of Highly Constrained Muscle Force Predictions for the Knee During Gait

Jonathan P. Walter, Darryl D. D'Lima, Thor F. Besier, and Benjamin J. Fregly

SBC2011-53583 491

Finite Element Predictions of Labrum and Cartilage Mechanics in Dysplastic Human HipsCorinne R. Henak, Ryan S. Davis, Benjamin J. Ellis, Michael D. Harris,

Andrew E. Anderson, Christopher L. Peters, and Jeffrey A. Weiss

xxix

SBC2011-53622 493

The Relationships Among Spatiotemporal Gene Expression, Histology, and Biomechanics

Following Full-Length Injury in the Murine Patellar Tendon

Nathaniel A. Dyment, Namdar Kazemi, Lindsey E. Aschbacher-Smith,

Nicolas J. Barthelery, Keith Kenter, Cynthia Gooch, Jason T. Shearn,

Christopher Wylie, and David L. Butler

SBC2011-53831 495

Changes in Capsule Function Following Anterior Dislocation Elucidate the Need for

Standardized Clinical Exams to Diagnose Shoulder InstabilityCarrie A. Voycheck, Daniel P. Browe, Patrick J. McMahon, and Richard E. Debski

SBC2011-53848 497

A Non-Linear Model to Describe the Material Properties of Single Lamellae in the

Human Annulus Fibrosus

Tina M. Nagel, Ramesh Raghupathy, Arin M. Ellingson, David J. Nuckley, and

Victor H. Barocas

PhD STUDENT PAPER COMPETITION: PHYSICAL EFFECTS ON CELLS

SBC2011-53326 499

Mechanical Stimulation of Scaffold-Free, Cell-Based Single Fibers for Tissue

Engineered TendonNathan R. Schiele, Ryan A. Koppes, and David T. Corr

SBC2011-53471 501

Piconewton Level Loading and Sub-Cellular Deformation of Bone Cells Using a Novel

Stokesian Fluid Stimulus Probe (SFSP)Danielle Wu, Peter Ganatos, Sheldon Weinbaum, and David C. Spray

SBC2011-53505 503

Finite Element Analysis of Nutrient Distribution and Cell Viability in Intervertebral Disc:

Effect of Compression and DegenerationAlicia R. Jackson, Chun-Yuh Huang, Mark D. Brown, and Weiyong Gu

SBC2011-53625 505

Calcium Efflux From Bone Matrix in Response to Mechanical LoadingXuanhao Sun, Eric S. McLamore, D. Marshall Porterfield, and Ozan Akkus

SBC2011-53641 507

Abrupt Recruitment of Medial Collagen Fibers in the Rabbit Carotid ArteryMichael R. Hill and Anne M. Robertson

SBC2011-53693 509

The Mechanical and Structural Effects of HIV Proteins on Murine Carotid Arteries

Laura Hansen, Manu Piatt, Roy L Sutliff, and Rudolph L. Gleason

REDUCED ORDER MODELS AND APPLICATIONS

SBC2011-53231 511

Effects of Lymphangion Subdivision in a Numerical Model of a Lymphatic Vessel

Chris Bertram, Charles Macaskill, and James E. Moore, Jr.

xxx

SBC2011-53433 513

Analysis of Aortic Wave Travel and Reflection Using Advanced Modeling Methods in

Simplified Geometries

Liesbeth Taelman, Joris Degroote, Abigail Swillens, Jan Vierendeels, and Patrick Segers

SBC2011-53479 515

A Coupled Simulation of Spinal Cord Blood Flow and Cerebrospinal Fluid Motion in the

Spinal Subarachnoid Space Based on In Vivo Measurements

Bryn Martin, Philippe Reymond, Olivier Baledent, Jan Novy, and Nikos Stergiopulos

SBC2011-53553 517

Experimentally Modeling Patient-Specific Fontan Circulations Including Respiration Effects

Using a Mock Circulatory SystemJohn A. Chiulli, Timothy A. Conover, Sharmad S. Joshi, Richard S. Figliola, and

Tain-Yen Hsia

SBC2011-53759 519

A Coupled Computational Framework for Multiscale Modeling and Optimization of Single

Ventricle RepairAlison L Marsden, Mahdi Esmaily Moghadam, Weiguang Yang, Alessia Baretta,

Chiara Corsini, Irene Vignon-Clementel, Francesco Migliavacca, Jeffrey Feinstein, and

Tain-Yen Hsia

SBC2011-53784 521

Effect of Continuous-Flow Left Ventricular Assist Device on Cardiac Function:

Simulation Study With a Biventricular Computer Model

Yajuan Wang, Antonio Ferreira, Bradley B. Keller, Marc Simon, and James F. Antaki

REHABILITATION, PROSTHESIS AND ORTHOTICS

SBC2011-53023 523

A Measurement Tool to Assess Hand Kinematics and Kinetics in Piano PlayersRita M. Patterson, George Kondraske, Eri Yoshimura, Shrawan Kumar, and Kris Chesky

SBC2011-53046 525

Changes in the COP Trajectory After Use of a CAD and FEA Designed Orthotic

Robert Rizza, Xue-Cheng Liu, John Thometz, Roger Lyon, Channing Tassone, and

S. Van Valin

SBC2011-53106 527

The Influence of Tibial Insert Design on Posterior Stabilized Total Knee ArthroplastyKinematics

Mehul A. Dharia, Marc Muenchinger, Eik Siggelkow, and Jeff E, Bischoff

SBC2011-53164 529

Novel Endoprosthesis for Limb Sparing of Canine Distal Radius Osteosarcoma Patients:

A Modular ApproachSnehal Shetye, Stewart Ryan, Nicole Ehrhart, and Christian Puttlitz

SBC2011-53305 531

Development of a Powered-Knee Transfemoral Prosthesis PrototypeCarl D. Hoover and Kevin B. Fite

xxxi

SBC2011-53489 533

Evaluation of the Biofidelity of the Hill and MIL-Lx Lower Leg Surrogates Under

Axial Impact Loading

Cheryl E, Quenneville and Cynthia E. Dunning

RESPIRATORY FLOWS

SBC2011-53097 535

Assessment of Pressure Oscillations Delivery to the LungA. M. Al-Jumaily, P. Reddy, and J. Mussa

SBC2011-53340 537

Flow Analysis in Upper Airway for an OSA Subject Before and After SurgeryY. Liu, J. Y. Ye, Y. X, Liu, and H. Y. Luo

SBC2011-53370 539

Experimental and Numerical Flow Visualization in Patient Specific Pre-OperativeHuman Airway Geometry

Mathias Vermeulen, Cedric Van Holsbeke, Tom Claessens, Jan De Backer,

Peter Van Ransbeeck, and Pascal Verdonck

SBC2011-53504 541

Airway Closure With Two Liquid Layers

Cheng-feng Tai, David Halpern, and James B. Grotberg

SBC2011-53717 543

Computational Model of Microbubble Flows During the Reopening of Airways

Xiaodong Chen and Samir N. Ghadiali

SBC2011-53941 545

A Study on the Parameters Influencing Clearance of Mucus During Cough in a

Model Trachea

Anpalaki J. Ragavan, Cahit A. Evrensel, and Peter Krumpe

SPINE I

SBC2011-53262 547

Adaptive Bone Remodeling Theory Applied to Cervical LaminoplastySwathi Kode, Nicole A. Kallemeyn, Joseph D. Smucker, Douglas C. Fredericks, and

Nicole M. Grosland

SBC2011-53283 549

The Effect of Muscle Loading on Internal Mechanical Parameters of the Lumbar Spine:A Finite Element Study

Benjamin C. Gadomski, John Rasmussen, and Christian M. Puttlitz

SBC2011-53301 551

Artificial Disc Versus Fusion: Effect on Three-Dimensional Dynamic In Vivo Cervical

Spine Motion

Colin P. McDonald, Michael J. McDonald, Nicole L. Ramo, Stephen W. Bartol, and

Michael J. Bey

xxxii

SBC2011-53694 553

Cervical Spine Movement Sequencing During Flexion-Extension

William J. Anderst, Michelle Schafman, William F. Donaldson, III, Joon Y. Lee, and

James D. Kang

SBC2011-53740 555

Robotic Simulation of an Eccentric Lever Arm Protocol and a Novel Head Weight Protocol

for Evaluation of the Subaxial Cervical Spine: An In Vitro Biomechancial ComparisonDaniel M. Wido, Denis J. DiAngelo, and Brian P. Kelly

SBC2011-53894 557

3D Analysis of Lumbar Spine Facet Joint Cartilage Thickness Distribution

Peter Simon, Alejandro A. Espinoza Orias, Naomi Kotwal, Todd Parrish, Howard S. An,

Gunnar B. J. Andersson, Rick D. Sumner, and Nozomu Inoue

SPINE II

SBC2011-53027 559

The Effect of Different Material Combinations on Wear of an Artificial Cervical Disc as

Standalone vs. Placed in a Ligamentous Motion SegmentS. Bhattacharya, V. K. Goel, A. Kiapour, and X. Liu

SBC2011-53111 561

Analysis of the Intervertebral Disc's Mechanical Behavior Under Impact Loading Conditions

David Jamison IV, Marco Cannella, Eric C. Pierce, Shawn K. Martin, and

Michele A. Marcolongo

SBC2011-53210 563

Mechanical Properties of Injured Human Cervical Spine Ligaments and Corresponding

Effect on Spinal Kinematics

P. Devin Leahy and Christian M. Puttlitz

SBC2011-53742 565

Three-Dimensional Characterization of Lumbar Lordosis in Torsion

J. A. Alland, A. A. Espinoza Orias, H. S. An, G. B. J. Andersson, and N. Inoue

SBC2011-53829 567

Level- and Region-Specific Properties of Young Human Lumbar Annulus

Brian D. Stemper, Narayan Yoganandan, Barry S. Shender, Glenn R. Paskoff,

Frank A. Pintar, and Jamie L. Baisden

TARGETED DELIVERY AND ELECTROPORATION

SBC2011-53138 569

Targeting Ovarian Cancer Cells With Rapidly Biodegradable L-Tyrosine Polyphosphate

Nanoparticles Decorated With Folate

Andrew J. Ditto, Nikki K. Robbishaw, Matthew J. Panzner, Wiley J. Youngs, and

Yang H. Yun

SBC2011-53215 571

Quantifying the Effects of Extracellular Conductivity on Transport During Electroporation

Mohamed M. Sadik, Jianbo Li, Jerry W. Shan, David I. Shreiber, and Hao Lin

xxxiii

SBC2011-53647 573

Targeted Gene Silencing With Light and a Silver Nanoparticle Antisense Delivery SystemPaige K. Brown, Ammar T. Qureshi, Daniel J. Hayes, and W. Todd Monroe

SBC2011-53816 575

Nanoftber Micro patterns for Controlled Release of Biomolecules

Walter Bonani, Claudio Migliaresi, and Wei Tan

SBC2011-53883 577

A Method to Delineate Irreversible Electroporation From Thermal Damage Validated

Ex Vivo With Real-Time TemperaturePaulo A. Garcia, John H. Rossmeisl, Jr., Thomas L. Ellis, and Rafael V. Davalos

SBC2011-53936 579

Irreversible Electroporation: An In Vivo Study Within the Dorsal Skin Fold Chamber

Zhenpeng Qin, Jing Jiang, Gary Long, and John C. Bischof

TENDON/LIGAMENT MECHANICSSBC2011-53186 581

Comparison of a Novel Nonlinear Viscoelastic Finite Ramp Time Correction Method to a

Heaviside Step AssumptionKevin L. Troyer and Christian M. Puttlitz

SBC2011-53531 583

Effect of Hormone Therapy on Tensile Strain of the Macaque Inferior Glenohumeral

Ligament

Haley A. Bunting, Ryan T. Cassilly, Brian Jin, Christopher S. Ahmad, Louis U. Bigliani,William N. Levine, and Thomas R. Gardner

SBC2011-53629 585

Effect of RhPDGF-BB-Coated Sutures on Tendon Healing in a Rat Model:

A Histological and Biomechanical StudyS. Cummings, J. Dines, C. K. Hee, H. K. Kestler, C. M. Roden, N. Shah, P. Razzano,

D. Dines, N. Chahine, and D. Grande

SBC2011-53835 587The Collagen Fiber Kinematics in the Anteroinferior Glenohumeral Capsule Are Not Affine-Predicted

Carrie A. Voycheck, Patrick J. McMahon, and Richard E. Debski

SBC2011-53855 589Mechanical Characteristics of Tissue Engineered Bone-Ligament-Bone Constructs

Following ACL Replacement in SheepJ. Ma, M. J. Smietana, E. M. Wojtys, L. M. Larkin, and E. M. Arruda

SBC2011-53877 591Whole Body Vibration Amplitude Levels Differentially Affect Tendon and LigamentStructural Properties

Benjamin V. Keller, Matthew L. Davis, Laurence E. Dahners, and Paul S. Weinhold

xxxiv

TISSUE GROWTH AND REMODELING: COMPUTATIONAL MODELING

SBC2011-53087 593

Biomechanical Modeling of Intrasac Pressure Changes and Vascular Remodeling After

Endovascular Repair of Abdominal Aortic AneurysmsS. Baek, S. T. Kwon, and J. E. Rectenwald

SBC2011-53392 595

Roles of Elastin, Muscle Contractility and Collagenous Stiffening in Aortic Aging:

A Thick-Walled Multi-Layered Model

A. Valentin, J. D. Humphrey, and G. A. Holzapfel

SBC2011-53399 597

Compaction and Anisotropy Induced by Remodeling of the Collagen Network's State of

Tension-Compression Transition

Thomas Nagel and Daniel J. Kelly

SBC2011-53623 599

A Microstructural Data Driven Multiscale Model for the Enzymatic Degradation and

Remodeling of Collagen Networks

Mohammad F. Hadi, Edward A. Sander, Jeffrey W. Ruberti, and Victor H. Barocas

SBC2011-53780 601

Microstructure Motivated Growth and Remodeling of the Lamina Cribrosa in

Early Glaucoma

Rafael Grytz, Ian A. Sigal, Jeffrey W. Ruberti, and J. Crawford Downs

SBC2011-53977 603

Abdominal Aortic Aneurysm Growth: The Association of Aortic Wall

Mechanics and GeometryChristopher B. Washington, Judy Shum, Satish C. Muluk, and EnderA. Finol

TISSUE GROWTH AND REMODELING: EXPERIMENTS

SBC2011-53183 605

In Vivo Actuation System for Mechanostimulation of Large Wound HealingUmut Atakan Gurkan, Alexandra Dubikovsky, Lynetta J. Freeman, Paul W. Snyder,

Russell D. Meldrum, and Ozan Akkus

SBC2011-53401 607

Correlation of Local Mechanical Environment to Mechanically Induced Tissue Phenotype

During Altered Bone Fracture HealingG. J. Miller, P. G. Patel, and E. F. Morgan

SBC2011-53418 609

Could Substrate Stiffness and Oxygen Tension Regulate Stem Cell Differentiation DuringFracture'Healing?

D. Burke and D. J. Kelly

SBC2011-53664 611

Non-Thermal Dielectric Barrier Discharge Plasma Promotes Vascularization ThroughReactive Oxygen Species

Krishna Priya Arjunan, Gary Friedman, and Alisa Morss Clyne

xxxv

SBC2011-53678 613

Extending Standard Rotational Rheometry for Small, Irregular, AnisotropicTissues and Gels

H. Cirka, W. Parr, S. Koehler, and K. Billiar

SBC2011-53798 615

Maternal Childbirth Injury Alters Vaginal Smooth Muscle ContractilityZegbeh C. Jallah, Laura Skoczylas, Suzan Stein, Naoki Yoshimura, Pamela Moalli, and

Steven Abramowitch

UNDERGRADUATE DESIGN COMPETITION IN REHABILITATION AND

ASSISTIVE DEVICES

SBC2011-53400 617

Bodyweight Apparatus Used to Apply Compression Garments for Lymphedema Patients

David DeRoche and Zachary Sharp

SBC2011-53484 619

Quantification of Dexterity Through a Novel Electronic Device

Avery L, Cafe, Dillon P. Eng, Rachel W. Jackson, Allison C. Scully, and Jessica A. Scully

SBC2011-53499 621

A Partial Weight Bearing Reminder Device for Rehabilitation After Lower Extremity SurgeryElsbeth Adams, Travis Kiser, Rochelle LaPorte, Tracy Roux, Eric Stanistreet, and

Caitlin Storey

SBC2011-53544 623

Tactile Surface Detector for a Prosthetic Hand

Kai Yuen Lim, Emily Cook, S. Philip Kirkpatrick, and Neophytos Palettas

SBC2011-53688 625

Stereoscopic Motion Tracking SystemA. Calderon, M. Dembele, B. Hossain, Y. Noor, and S. Ovsiew

SBC2011-53821 627

Automated Diabetes Testing Device for the One-Armed/Disabled Patient

Ali Abdallah, Brandon Heid, Hajra Khan, and Nigil Valikodath

UPPER AND LOWER EXTREMITY

SBC2011-53240 629

The Relationship Between In-Vivo Glenohumeral Joint Motion and Joint Morphology in

Rotator Cuff Repair Patients and Healthy Control Subjects

Cathryn Peltz, Kristin Ciarelli, Jeffrey Haladik, Michael McDonald, Nicole Ramo,

Vasilios Moutzouros, and Michael Bey

SBC2011-53307 631

Shoulder Rotational Laxity is Related to Pitching Mechanics

Hongsheng Wang, Koco Eaton, and Nigel Zheng

xxxvi

SBC2011-53323 633

Influence of Humeral Version and Deltoid Tension on Glenohumeral Kinematics After

Reverse Total Shoulder ArthroplastyHeath B. Henninger, Alexej Barg, Robert Z. Tashjian, Robert T. Burks, Kent N. Bachus, and

Andrew E. Anderson

SBC2011-53506 635

Experimental Validation of Computer-Simulated Glenoid Preparation for Total Shoulder

ArthroplastyCharlie Yongpravat, Jonathan D. Lester, Alen Trubelja, R. Michael Greiwe, Comron Saifi,

William N. Levine, Louis U. Bigliani, Christopher S. Ahmad, and Thomas R. Gardner

SBC2011-53651 637

Effect of Kinematics on the Wear Rate of the Patella Femoral Artificial Joint

Raman Maiti, John Fisher, Zhongmin Jin, Liam Rowley, and Louise Jennings

SBC2011-53895 639

Comparison of Normal Capitate Mid-Carpal Joint Mechanics With the Effects of

Scapholunate Dissociation InjuryMadhan Sai Kallem, Sang-Pil Lee, Terence E. Mclff, E. Bruce Toby, and

Kenneth J. Fischer

WOO SYMPOSIUM: APPLICATION OF ROBOTICS TO ANALYZE

JOINT STABILITY

SBC2011-53416 641

Extracellular Matrix Bioscaffolds to Enhance ACL Healing: Impact on the Contribution of the

MCLto Joint StabilityMatthew B. Fisher, Ho-Joong Jung, Kwang E. Kim, Patrick J. McMahon, and

Savio L-Y. Woo

SBC2011-53507 643

Injury to the Glenohumeral Capsule During Anterior Dislocation Leads to Higher Joint

Contact Forces During Simulated Clinical Exams

Carrie A. Voycheck, Daniel P. Browe, Patrick J. McMahon, and Richard E. Debski

SBC2011-53658 645

Characterization of a Biomechanical Animal Model for Intact Knee Kinematics and ACL

Function Using 6-DOF Robotic Technology

Daniel V. Boguszewski, Safa T. Herfat, Christopher T. Wagner, David L. Butler, and

Jason T. Shearn

SBC2011-53799 647

A Robotic Model of Hip Dislocation Potential: Total Hip Arthroplasty Versus Femoral

Head ResurfacingR. W. Colbrunn, J. J. Bottros, C. B. Greeson, A. van den Bogert, and W. K. Barsoum

xxxvii

SBC2011-53836 649

Using Robotic Testing System to Investigate ACL Reconstructions in Restoring the

Normal Knee Joint Biomechanics: Experience at Harvard Medical School

Guoan Li, Hemanth Ft. Gadikota, and Thomas J. Gill

SBC2011-53884 651

Novel Robotic System for Joint Mechanical Tests Using Velocity-Impedance Control

Hiromichi Fujie and Hitoshi Yagi

WOO SYMPOSIUM: COMPUTATIONAL MODELING OF LIGAMENTS AND

TENDONS

SBC2011-53061 653

Computational Modeling of Ligaments and Tendons: A Tribute to Dr. Savio Lau-Yuen Woo

Kai-Nan An

SBC2011-53277 655

Experimentally and Theoretically Narrowing Carpal Arch Width to Increase the Area

Formed by the Transverse Carpal LigamentSuk H. Yu, Tracy A. Mondello, and Zong-Ming Li

SBC2011-53358 657

Resident's Ridge Formation Can Be Explained by ACL Force-Induced Bone RemodelingHiromichi Fujie, Yohei Matsuda, and Konsei Shino

SBC2011-53588 659

Continuity and Affine Fiber Kinematics in Biaxial Tension of the Supraspinatus Tendon

Spencer E. Szczesny, John Peloquin, Sarah Ilkhani-Pour, Daniel H. Cortes,Jennifer A. Kadlowec, Louis J. Soslowsky, and Dawn M. Elliott

SBC2011-53687 661

Effects of Surgical Repair or Reconstruction on Radiocarpal Mechanics From Wrists With

Scapholunate InjuryJoshua E. Johnson, Sang-Pil Lee, Terence E, Mclff, E. Bruce Toby, and

Kenneth J. Fischer

SBC2011-53904 663

Tibiofemoral Kinematics of the Knee During the Stance Phase of Gait After ACL DeficiencyChih-Hui Chen, Jing-Sheng Li, Ali Hosseini, Hemanth Reddy Gadikota, Michal Kozanek,Thomas J. Gill, and Guoan Li

WOO SYMPOSIUM: FUNCTIONAL TISSUE ENGINEERING OF

LIGAMENTS AND TENDONS

SBC2011-53204 665

Tendon Stem Cells and Platelet-Rich Plasma for Repair of Injured TendonsJames H.-C. Wang

SBC2011-53233 667

MMP and Matrix Degradation in Tendon

Graham Riley

xxxviii

SBC2011-53533

Functional Tissue Engineering for Repair of Load-Bearing Musculoskeletal Tissues:

History and PerspectiveDavid L. Butler

SBC2011-53610

Augmentation Devices for Rotator Cuff RepairKathleen A. Derwin and Joseph P. lannotti

SBC2011-53656

Tenocytes, Phenotypes, Biomarkers and Functions: Roles in Bioartificial Tendons

A. J. Banes, J. Qi, J. M. Dmochowski, M. Tsuzaki, A. N. Banes, D. Bynum, S. Gomez, and

M. E. Wall

SBC2011-54028

Innovative Scaffold Design for Soft Tissue-to-Bone Interface Tissue EngineeringSiddarth D. Subramony, Jeffrey P. Spalazzi, Kristen L. Moffat, Scott A. Rodeo, and

Helen H. Lu

WOO SYMPOSIUM: TISSUE MECHANICS

SBC2011-53284

Stiffness of the Transverse Carpal Ligament Under the Influence of CollagenaseRyan K. Prantil, Tracy A. Mondello, Suk H. Yu, Khurram Pervaiz, Savio L.-Y. Woo, and

Zong-Ming Li

SBC2011-53397

Influence of Decorin and Biglycan on Tensile Viscoelastic Properties in Knockout Mice

LeAnn M. Dourte, Lydia Pathmanathan, Renato V. lozzo, and Louis J. Soslowsky

SBC2011-53520

Failure Properties of the Simian Inferior Glenohumeral LigamentRyan T. Cassilly, Haley A. Bunting, Brian Jin, Christopher S. Ahmad, Louis U. Bigliani,

William N. Levine, and Thomas R. Gardner

SBC2011-53545

The Effect of Patellar Orientation on the Stiffness of the Porcine Femur-Medial

Patellofemoral Ligament-Patella ComplexKwang E. Kim, Shanlin Hsu, Matthew B. Fisher, and Savio L.-Y. Woo

SBC2011-53841

Characterizing the Ex-Vivo Properties of Prolapse Meshes

Andrew J. Feola, William R. Barone, Jon Shepherd, Pam Moalli, and

Steven Abramowitch

SBC2011-54029

A Tribute to Professor Savio L. Y. Woo: A Superb Scholar and Great Leader in BioengineeringShu Chien

xxxix