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86 th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY Principles of Ultrasound Imaging Image Optimization Robert A. Levine, MD, FACE, ECNU Thyroid Center of New Hampshire Geisel School of Medicine at Dartmouth College Disclosures: No relevant financial or corporate conflicts of interest. The use of investigational drugs will not be discussed

Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

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Page 1: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Principles of UltrasoundImaging

Image Optimization

Robert A. Levine, MD, FACE, ECNUThyroid Center of New Hampshire

Geisel School of Medicine at Dartmouth College

Disclosures: No relevant financial or corporate conflicts of interest. The use of investigational drugs will not be discussed

Page 2: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image OptimizationCreate the sharpest image to allow tissue discrimination.

• Equipment factors:• Quality of Transducer• Quality of Electronics• Image Enhancement and Compound Imaging

• User Adjustments:• Depth, Gain, Frequency• Focal zones – Number and Location• Compound Imaging• Tissue Harmonic Imaging• Dynamic range

Page 3: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Page 4: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Optimal Depth

Page 5: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image Optimization

• Gain• Overall Gain• Time Gain Compensation

• Multiple channels corresponding to depth• User adjustable to achieve best image quality at region of

interest

• Focal Zone(s)• Adjustable depth and number• Greater number of zones slows refresh rate

Page 6: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Optimal Gain

Page 7: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Page 8: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Optimal Time Gain Compensation

Page 9: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Resolution

• Resolution is the ability to discriminate two structures as separate entities

• Types of resolution :Axial (distance from the transducer)Lateral (transverse)Azimuthal (thickness of imaging plane)

Page 10: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Resolution

LATERAL(side to side)

AXIAL(distance from transducer)AZIMUTHAL

(up-down)

Page 11: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Resolution• Ability to discriminate two adjacent objects as

separate entities.• The narrower the beam, the better the lateral

resolution. The higher the frequency the better the axial resolution.

Poor focus

Good focus

Image

Page 12: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Focus and Resolution• Focused beam width determines Lateral and Azimuthal

Resolution

• Pulse duration (frequency) determines Axial Resolution• (axial resolution = 1/2 spatial pulse length)

• Practical Consideration - As frequency increases, axial resolution improves, but depth of imaging decreases.• The number and depth of the focal zones are often

adjustable and indicated on the display

Near field (Fresnel Zone) Large variations of intensity

Far field (Fraunhofer Zone) Greater variation with greater distance.Focal Zone - Area of maximal narrowing

Page 13: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Adjustment of number and position of focal zones

Page 14: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Adjustment of number and position of focal zones

Page 15: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Single focal zone

Page 16: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Four focal zones

Page 17: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Frequency and Resolution

Higher frequency gives better resolution.Higher frequency gives less penetration.Need to find best compromise for depth of interest

Page 18: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image Optimization - Frequency

• Choose highest frequency (12-15 MHz) that allows adequate depth penetration.

• Lower frequencies (7-10 MHz) for deep structures or very obese subjects

Page 19: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Frequency and depth

Page 20: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Advances in Technology Signal Processing

• Image Enhancement• Noise reduction• Edge sharpening

• Utilization of CT and MRI reconstruction algorithms• Beam Steering• Spatial compounding

Page 21: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image Optimization- Compounding

Page 22: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Signal Processing – Compunding

Page 23: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Comparison of standard and processed images

Page 24: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Effect of Compound Imaging on Artifacts

Comet Tails

Page 25: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Effect of Compound imaging on Artifacts

Edge Artifact and Enhancement

Page 26: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Effect of Compound Imaging on Spongiform Nodule

Page 27: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Tissue Harmonic Imaging

At higher power tissue will reverberate and produce harmonics of the original frequency.Selective detection of the second harmonic.

Page 28: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Tissue Harmonic Imaging• Different tissues will have varying degrees

of harmonic generation• Selective detection of harmonic

• Higher frequency: Improved resolution• Less distance: Less noise• Increased contrast

Page 29: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Tissue Harmonic Imaging

• Increased conspicuity• Improved signal to noise for deeper structures

Page 30: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image Optimization – Dynamic range

• May increase conspicuity of subtle lesions

Page 31: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Doppler Shift

Page 32: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Color and Power Doppler

Meritt, 1998

Page 33: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Color and Power Doppler

Meritt, 1998

Page 34: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Color and Power Doppler

• Color Doppler• Provides information

regarding direction and velocity.

• More useful in vascular studies

• Power Doppler• No information

regarding velocity• Less angle

dependence• Less noise• Increased sensitivity

for detection of flow

Page 35: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Doppler – Lymph nodes

In normal nodes vessels enter centrally at the hilus, and spread along the long axis.In malignant nodes aberrant vessels enter peripherally in the node capsule. Increased (disordered) vascularity may be seen peripherally and centrally.

Page 36: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Doppler of Nodes• Demonstration of Chaotic or peripheral

vascularity in malignant nodes• Can be seen in reactive nodes

• Normal vascularity is reassuring• Power Doppler for high sensitivity• Use low wall filter• Use a low PRF < 800

• Low wall filter and low PRF both increase the sensitivity for detection of low flow.

Page 37: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Achieving the highest sensitivity with Doppler imaging.

High Doppler sensitivity needed for lymph nodes.

• Power Doppler• Maximum Doppler gain without noise.• Low Pulse Repetition Frequency

• PRF < 800• Low wall filter.

Page 38: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

PRF 1400 700

Page 39: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

PRF 700 – Wall filter varies

Page 40: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Page 41: Principles of Ultrasound Imaging Image Optimization · 86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, Colorado NOT FOR REPRODUCTION – FOR ATA

86th Annual Meeting of the American Thyroid Association, September 21, 2016, Denver, ColoradoNOT FOR REPRODUCTION – FOR ATA ULTRASOUND COURSE USE ONLY

Image Optimization Summary and Conclusions

• High quality equipment is preferable, BUT a great ultrasonographer using low quality equipment will obtain better images than a lousy ultrasonographer with great equipment.

• “I need to find out what type of piano Mozart played so I can sound like him.”

• User adjustments of gain, depth, frequency, focal zones, dynamic range, spatial compounding, pulse repetition frequency, and wall filter will give the optimal image quality.