02 Octobre 2012

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The key partner in the developmentThe key partner in the developmentof microencapsulated productsof microencapsulated products

Capsulæ develops for its clients throughout the industrial world customized solutions Capsulæ develops for its clients throughout the industrial world customized solutions which facilitate and optimize the performance of ingredients and active compounds,via microencapsulation.

Capsulæ offers a full range of services for developing products and processes based on microencapsulation, including the following:

Design of innovative solutions and Feasibility studies

Encapsulation problem solving

Scaling-up studies and Pilot-scale evaluation

Support at the industrialization stage

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The key partner in the developmentThe key partner in the developmentof microencapsulated productsof microencapsulated products

Created in 2006, the company is the brainchild of three researchers who have an Created in 2006, the company is the brainchild of three researchers who have an accumulated experience of over 50 years in the field of encapsulation of active principles for a wide range of applications.

The management team is made up of:

Arnaud PICOT , CEO & co-founder

Samira EL MAFADI , R&D Manager & co-founder

Denis PONCELET , Scientific Director & co-founder

Gisèle ONGMAYEB , Project Manager for chemistry applications

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AA technological solution to a multitudetechnological solution to a multitudeof industrial problemsof industrial problems

Microencapsulation includes all the technologies that allow the coating or entrapment of Microencapsulation includes all the technologies that allow the coating or entrapment of active ingredients inside individual particles whose size varies from several microns to several millimeters.

Encapsulating an active principle meets 4 main objectives which can be combined:

ImmobilizationProtection or stabilization against adverse environmental factors Controlled or delayed release on the action site Functionnalization or structuration

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AA technological solution to a multitudetechnological solution to a multitudeof industrial problemsof industrial problems

Developing a process or a product based on micro-Developing a process or a product based on micro-encapsulation supposes the selection of one method among a large number of technologies, the optimizationof the numerous operating conditions, the definition ofa formulation.

The solution must fulfill the particular conditions of the application, the project specifications, and respect the regulation. The process developed must be scalable to in-plant production, taking into account all the technological constraints of the industry, and at an acceptable manufacturing cost.

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A unique A unique pluripluri--technologicaltechnological expertiseexpertise

The wide range of microencapsulation technologies that the Capsulæ team masters allows a great flexibility regarding the solutions we offer our clients, from both a technical and economic point of view.

Our know-how and skills are cover more specifically the following technologies:

Dripping technologies , as seen in our range of solutions

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A unique pluriA unique pluri--technologicaltechnological expertiseexpertise

The wide range of microencapsulation technologies that the Capsulæ team masters allows a great flexibility regarding the solutions we offer our clients, from both a technical

Emulsion-based technologies , as seen in our range of solutions

and economic point of view.

Our know-how and skills are cover more specifically the following technologies:

© Capsulæ

A unique pluriA unique pluri--technologicaltechnological expertiseexpertise

The wide range of microencapsulation technologies that the Capsulæ team masters allows a great flexibility regarding the solutions we offer our clients, from both a technical

Coating technologies , as seen in our range of solutions

and economic point of view.

Our know-how and skills are cover more specifically the following technologies:

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A unique pluriA unique pluri--technologicaltechnological expertiseexpertise

Capsulæ boasts a wide range of laboratory and pilot equipments that are specifically dedicated to microencapsulation, as well as a set of high-performance tools for analysis and characterization (microbiological and physico-chemical analyses laboratories):

Particle size analysis ; Tomography Optical microscopy, SEM, CLSMThermal analysis (DSC, TGA) ; DMAGC/MS ; HPLCFTIR, UV-Vis/Fluorescence ; NMRPowder characterization(Aw, %DM, flowability, porosity…)Rheological analysis ; Surface tension; Zeta potential…

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A wide range of possible usesA wide range of possible uses

Microencapsulation can be applied to all sectors of industrial activity.

Capsulæ has developed its own specific expertise and know-how for the encapsulation of Capsulæ has developed its own specific expertise and know-how for the encapsulation of active principles in the following domains:

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Food & NutritionFood & Nutrition

Microencapsulation of food ingredients is useful in meeting a number of objectives, including protection during the food

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incorporation process and subsequent storage, taste and odor masking and controlled/prolonged release.

A wide range of functional, lipophilic and hydrophilic ingredients in powder or liquid form can be encapsulated, including:

Probiotic micro-organisms, enzymes

Vegetable oils, fish oils

Aromas, fragrances, plant extracts

Mineral salts, vitamins, amino acids

…

FeedFeed & Animal & Animal HealthHealth CareCare

Whether it be for pets, livestock or even aquaculture, microencapsulation greatly facilitates the introduction

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(e.g., reducing dust, improving appetence, formulating incompatible compounds), increases stability (e.g., phytogenic additives or probiotic micro-organisms during pelletizing) and allows for the controlled/delayed release (e.g., ruminal bypass for certain vitamins and amino acids) of various active principles for multiple applications:

Complete & complementary feed

Nutritional specialties & supplements

Veterinary formulas, vaccines

Artificial insemination

Agriculture & EnvironmentAgriculture & Environment

Improving products used in crop protection first requires the optimization of the biological profile of the active compounds,

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a reduction in the product dose, better flexibility for the user and an improved applicability.

Whether it is for the traditional agro-chemical industry market or the biological protection of crops, encapsulation is an undeniably essential and effective process, used for the following compounds:

Insecticides and fungicides

Herbicides and fertilizers

Repellents and larvicides

Micro-organisms for soil inoculation, biopesticides

Home & Personal CareHome & Personal Care

Microencapsulating the main ingredients found in detergents significantly improves their effectiveness and greatly

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facilitates their handling. When applied to the personal care market, encapsulation provides distinct advantages as it enables trapping of volatile compounds, association of incompatible ingredients, as well as a product differentiation.

All these elements constitute determining factors that can develop and improve the performance of products such as:

Cosmetic creams

Shampoo, toothpaste, soap and shower gels

Washing powders and washing-up liquids

Household products

Fine & Specialty ChemicalsFine & Specialty Chemicals

The field of fine and specialty chemicals is constantly evolving since the emergence of strong regulatory constraints that

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require environmentally-friendly solutions to be developed.

Capsulae has acquired both skills and expertise in developing new techniques using biodegradable materials and restricting the use of organic solvents. These techniques can be used for the following applications:

Adhesives & Sealants

Paints & Coatings

Building & Construction materials

Self-Healing & Phase-Change materials

A thorough and customized accompanimentA thorough and customized accompaniment

Our offer is based on the idea of offering an accompaniment that is broken down into different stages and specifically adapted to meet the needs of our clients:

© Capsulæ

A thorough and customized accompanimentA thorough and customized accompaniment

Our offer is based on the idea of offering an accompaniment that is broken down into different stages and specifically adapted to meet the needs of our clients:

© Capsulæ

A thorough and customized accompanimentA thorough and customized accompaniment

Our offer is based on the idea of offering an accompaniment that is broken down into different stages and specifically adapted to meet the needs of our clients:

© Capsulæ

A thorough and customized accompanimentA thorough and customized accompaniment

Our offer is based on the idea of offering an accompaniment that is broken down into different stages and specifically adapted to meet the needs of our clients:

© Capsulæ

A thorough and customized accompanimentA thorough and customized accompaniment

Our offer is based on the idea of offering an accompaniment that is broken down into different stages and specifically adapted to meet the needs of our clients:

© Capsulæ

CapsulæRue de la GéraudièreBP 8222544322 Nantes cedex 3FRANCE

� + 33(0)2 40 94 34 62� contact@capsulae.com � www.capsulae.com

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02 Octobre 2012

© Capsulæ