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Sandor G.Vari, M.D. 1 5/12/2014 Preconference Workshop – „Protect and Publish“ May 28 – 29, 2014 Bridges in Life Sciences 9 th Annual Conference May 29 – June 1, 2014

Preconference Workshop – „Protect and Publish“ May 28 – 29 ... - Workshop... · In 2012 CSMC converted the Association into the Association for Regional Cooperation in the

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Page 1: Preconference Workshop – „Protect and Publish“ May 28 – 29 ... - Workshop... · In 2012 CSMC converted the Association into the Association for Regional Cooperation in the

Sandor G.Vari, M.D. 1 5/12/2014

Preconference Workshop – „Protect and Publish“

May 28 – 29, 2014

Bridges in Life Sciences 9th Annual Conference

May 29 – June 1, 2014

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Sandor G.Vari, M.D. 2 5/12/2014

Organizing Committee USA - Cedars-Sinai Medical Center, Los Angeles, California Edward Prunchunas Senior Vice President for Finance and Chief Financial Officer, Cedars-Sinai Medical Center & Chairman of the Supervisory Board of the RECOOP HST Association Shlomo Melmed, M.D., Senior Vice President, Academic Affairs, Dean of the Medical Faculty, Cedars-Sinai Medical Center Sandor G. Vari, MD Director, International Research and Innovation Management Program, Cedars-Sinai Medical Center & President of the RECOOP HST Association Arora Chander Chander P. Arora, PhD Research Project Adviser, International Research and Innovation Management Program, Cedars-Sinai Medical Center & RECOOP HST Association Research Project Management Croatia Dr. Livia Puljak , MD., Ph.D., Assistant Professor, Department of Anatomy, Histology and Embryology, School of Medicine, University of Split Prof. Ana Marusic, MD, PhD Chair, Department of Research in Biomedicine and Health, School of Medicine, , University of Split & Co-editor in Chief, Journal of Global Health, www.jogh.org Marija Heffer, MD, PhD Professor, Department of Medical Biology, School of Medicine, Josip Juraj Strossmayer University of Osijek

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Preconference Workshop – „Protect and Publish“ Venue: HOTEL DUJAM May 27 – 29, 2014 Bridges in Life Sciences 9th Annual Scientific Conference in Split, Croatia Venue: ATRIUM HOTEL May 30 – 31, 2014Hotel accommodations Hotel Accommodation HOTEL DUJAM *** & YOUTH HOSTEL, Velebitska 27, 21000 Split – Croatia, Tel. + 385 (0) 21/273-080; www.hoteldujam.com BEST WESTERN Hotel Art ****, UlicaSlobode 41, 21000 Split, Croatia, Tel: +385 (0)21 302-302; http://www.bestwestern.com/ ATRIUM HOTEL ****** Domovinskog rata 49a, 21000 Split, T.+385 21 200 000; www.hotel-atrium.hr

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The Association for Regional Cooperation in the (RECOOP) Fields of Health, Science

and Technology (HST) Short Name: RECOOP HST Association 1. Introduction In 2006 Cedars–Sinai Medical Center (CSMC) with eleven CEE universities and academic organizations from six countries (Croatia, Czech Republic, Hungary, Romania, Slovakia, and Ukraine) formed the Regional Cooperation for Health, Science and Technology (RECOOP HST) Association. In 2012 CSMC converted the Association into the Association for Regional Cooperation in the Fields of Health, Science and Technology is registered by the Court of Debrecen in Hungary under the registry number 4160 on May 10, 2012, TAX ID: 18299140-1-09. Members of the Association from 9 countries (Croatia, Czech Republic, Denmark, Hungary, Romania, Slovak Republic, Ukraine and USA) and 14 higher education or research organizations. Members of the RECOOP HST Association:

• Cedars – Sinai Medical Center, Los Angeles, USA • School of Medicine University J. J. Strossmayer Osijek, Croatia • IKEM - Institute for Clinical and Experimental Medicine, Prague, Czech Republic • Institute of Macromolecular Chemistry Academy of Sciences, Czech Republic • Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech

Republic • Faculty of Pharmacy, University of Copenhagen, Denmark • University of Debrecen, Hungary • University of Pecs, Hungary • University of Szeged, Hungary • Carol Davila University of Medicine and Pharmacy, Bucharest, Romania • Slovak Medical University, Bratislava, Slovakia • Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv,

Ukraine • Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine • Danylo Halytsky Lviv National Medical University, Lviv, Ukraine

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2. International Partnerships of CSMC RECOOP HST Association World Health Organization (WHO) RECOOP HST Mother and Child Health Network was one of the partners of the International PREterm BIrth Collaborative (PREBIC www.prebic.net ) of the World Health Organization, Department of Reproductive Health and Research (http://www.who.int/reproductive-health/index.htm ). World Intellectual Property Organization (WIPO) Beside research opportunities the RECOOP Association inspires young scientists and clinical researchers for creative thinking, and helps to learn how to make decision on “publish and disclose” or “publish and protect”. The Association is working with the World Intellectual Property Organization (WIPO http://www.wipo.int) to train faculty members, managers, young scientists, clinicians and for Ph.D. students for innovation management and technology transfer from the RECOOP HST Association. The members of the participating organizations are taking the WIPO World Wide Academy (WWA) Distance Learning (DL) courses and until 2011 more than 500 faculty members were trained from the Association. National Institutes of Health (NIH) The first “Bridges in Life Sciences” regional networking meeting was organized in October 2003 by Cedars – Sinai Medical Center (CSMC) with four Hungarian Universities along with the Fogarty International Center (FIC) at the National Institutes of Health (NIH) in Budapest, Hungary. On June 4, 2008 the representative of the RECOOP Association meet with the representatives of the Division of International Relations, John E. Fogarty International Center for Advanced Study in Health Sciences, NIH, DHHS, USA and agreed to continue the “Bridges in Life Sciences” regional networking meeting organized in October 2003. The 4th Annual Scientific Meeting took place in Debrecen, Hungary on April 4 – 5, 2009 with the Visegrad Group’s (V4) academic organizations and NIH funded PIs from the USA with robust collaborative works in the CEE Countries. The host organization University of Debrecen on the behalf of the Association applied for a Standard Grant and CSMC provided the matching fund. The Bridges in Life Sciences US - CEE Regional Networking Meeting provided opportunity for 60 CEE RECOOP young scientists selected from more than 100 abstracts by the Scientific Advisory Board of the RECOOP Association and additional 20 young Ukrainian scientists was selected for the Young Scientists Forum with the support of California Association to Aid Ukraine (CAAU). The U.S. Government Global Health Initiative Ms. Lois Quam, Executive Director of U.S. Government Global Health Initiative, U.S. Department of State in her letter sent to the Bridges of Life Sciences 7th Annual Conference recognized the RECOOP HST Association Networks’ research activities as valuable assets of Global Health Initiative. Visegrád Group (V4) From 2008 the members of the RECOOP HST Association with the financial support of Cedars – Sinai Medical Center applied for 20 Standard Grants and won 14, also one Strategic Grants.

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During the last four years the RECOOP HST Association won 14 Standard Grants (20810243, 20820016, 20820040, 20820041, 20910138, 20920001, 20920002, 20920023, 20920024, 20910138, 21010083, 21010070, 21020052, and 21110096) to support the formation and management of research networks and multinational - multidisciplinary research projects. Also the IVF Standard Grants helped to build support networks for Biosafety and Biosecurity, Animal use in Research, Clinical Research Management, Research and Innovation Management Training. The buildup of the RECOOP Life Science Research Platform sponsored by the International Visegrad Fund Strategic Grant (31110035) “Future of Visegrad Four Families Depends on Healthy Women and Children”. The last five years IVF and CSMC-RECOOP extended activities toward the EU Eastern Partnership, the Visegrad+ Western Balkans and the RECOOP HST Association is building bridges to United States Global Health Initiative. The IVF grants won by CSMC – RECOOP also helped the International Visegrad Fund to move toward to the 21st Century and broaden the scope of funded activities in the Visegrad Group to involve more young scientists into the new biotechnology developments, could create innovative ideas, new medical treatment modalities and jobs in the region. 1. Research Capacity Building The RECOOP HST Association’s main goal is to enhance research collaboration and provide platforms for scientific networking in life sciences within the Visegrad Four Countries, Central - Eastern Europe, and Western Balkan. The research priority of the Association is women's and child’s health in the Visegrad Four European Macro-Region (Czech Republic, Hungary, Poland and Slovakia) and the neighboring countries (Belarus, Bosnia and Herzegovina, Croatia, Moldova, Macedonia, Montenegro, Romania, Serbia and Ukraine). The Association paves the way toward GLOBAL Research Programs of the National Institutes of Health, the World Health Organization and private funds (Gates, Clinton). In the last six years the RECOOP HST Association/Association implemented translational and retro - prospective clinical research in the Mother and Child Health (M&CH), the Women’s Health and Cardiovascular Diseases (WH&CVD) and in the NanoBioTechnology (NBT) Research Networks. The Mother and Child Health and the Women’s Health and Cardiovascular Diseases retro and prospective clinical research studies are using web based electronic data entry forms (EDEF http://www.flexiform.eu/). Beside the management of research networks for multinational - multidisciplinary research projects, the RECOOP HST Association also built support networks for Biosafety and Biosecurity, Animal use in Research, Clinical Research Management, Research and Innovation Management Training.

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In the RECOOP Research Networks 147 scientists are working in 18 research projects in clinical, basic and translational research studies to investigate biological pathways leading to gender differences in cardiovascular diseases, preterm birth, breast, cervical and brain tumors. In 2012 the RECOOP HST Association is integrated the multidisciplinary, multicenter research studies of the RECOOP Research Networks in the RECOOP Life Science Research Platform and formed 18 CSMC RECOOP Research Centers (CRRC) from 7 countries (Croatia, Czech Republic, Hungary, Poland, Romania, Slovak Republic, and Ukraine) working on translational and clinical research in the field of Genomics - Proteomics, Epigenetics, Metagenomics, Molecular Biology, Metabolomics and Nano-biotechnology. The CSMC - RECOOP Research Centers (CRRC):

Cardiovascular Disease and Women’s Health: Lifestyle intervention in women’s cardiovascular health with different reproductive and risk factors Jan Pitha M.D., Ph.D., Head of Laboratory for Atherosclerosis Research Department of Cardiology, IKEM - Institute for Clinical and Experimental Medicine, Prague, Czech Republic Myocardial contractile dysfunction Attila Borbely, M.D., Ph.D., Cardiologist, Institute of Cardiology, Medical and Health Science Center, University of Debrecen, Hungary The role of myofilamentary protein changes in diastolic dysfunction of newborns Zoltan Papp, M.D., Ph.D., D.Sc., Institute of Cardiology, Clinical Physiology Department, University of Debrecen, Hungary Obesity, bone density and cardiovascular diseases Professor Martin Gajdoš, M.D, Ph.D. and Dr. Zora Krivosikova, PhD Medical Faculty, Dept. of Clinical and Experimental Pharmacotherapy, Slovak Medical University, Bratislava, Slovakia Obesity, stress and cardiovascular function Professor Marija Heffer MD, PhD, Department of Biology and Neuroscience, School of Medicine University Josip Juraj Strossmayer Osijek

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Oxidative stress markers for metabolic and cardiovascular diseases Professor Elizabeta Has-Schön, PhD, Department of Biology, University J.J. Strossmayer, Osijek, Croatia Role of semicarbazide sensitive amine oxidase (SSAO) in Cardiovascular Diseases (endothelial cells and/or adipocytes) Professor Éva Szökő, Ph.D., D.Sc., Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University Vitamin D deficiency and effect on neurotransmitters in diabetes, ischemic heart disease and preterm birth Tatiana Borisova, Department of Neurochemistry, Palladin Institute of Biochemistry NAS of Ukraine Glycosylation and Bioseparation András Guttman, Ph.D., D.Sc., MHAS, Research Centre for Molecular Medicine, Horváth Laboratory of Bioseparation Sciences, Medical and Health Science Center, University of Debrecen, Hungary Mother and Child Health: Iron intake and preterm birth Chander P. Arora, PhD, Cedars-Sinai Medical Center International Research and Innovation Management Program, Los Angeles, CA, USA Cervical fluid IL-6 - a possible predictor of early onset sepsis in pregnancies complicated by late PPROM Dr. Marian Kacerovsky, MD, Department of Obstetrics and Gynecology, University Hospital in Hradec Kralove; Czech Republic Animal models to study preterm birth Professors Gyorgy Falkay, PhD, DSc. & Robert Gaspar, PhD Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Hungary Enterovirus infection in mother, neonate, infants and follow up in child development Professor Shubhada Bopegamage, Ph.D.,Head, Entervirus Laboratory, Virology Department, Slovak Medical University, Bratislava, Slovak Republic Screening mothers and newborns for cytomegalovirus infection William J. Britt, M.D., University of Alabama- Birmingham, Alabama, USA and Iuliana Ceausu, M.D., Ph.D, the Department of Obstetrics and Gynecology of “Dr. I. Cantacuzino” Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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NanoBioTech and Cancer: Iron nanoparticles for monitoring different diseases, (regenerative medicine, cardiovascular and cancer) Professor Daniel Horák, Ph.D. Head of the Department of Polymer Particles, Institute of Macromolecular Chemistry, Academy of Sciences, Prague, Czech Republic Tatiana Borisova, PhD, DSc, Head, Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiyv, Ukraine Biofunctionalization of nanoparticles and targeted drug delivery Studies, Professor Rostyslav Stoika, PhD, D.Sc., Department of Regulation of Cell Proliferation and Apoptosis, Institute of Cell Biology, National Academy of Sciences of Ukraine Targeted drug delivery for cancer treatment Professor Roman Bogdanovych Lesyk, Ph.D., D. Sc, Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University, Lviv Ukraine Tunable nanocrystals for biomedical imaging Artur Podhorodecki, Ph.D. Institute of Physics, Wroclaw University of Technology, Wroclaw, Poland In vitro and in vivo immune assays for evaluation of immunotoxic effect of nanoparticles MUDr. Jana Tulinska, PhD. Laboratory of Immunotoxicology, Slovak Medical University, Bratislava, Slovakia

The participating CRRCs from the member universities and research organizations implemented research programs for Medical and Ph.D Students. RECOOP Life Science Research Platform already realized short term (1-2 years) pilot research studies. The Networks continue the translational and clinical research studies in midterm (5 years), and the RECOOP HST Life Science Research Platform shall plan to continue the clinical research studies for minimum 20 - 30 years and follow up the women, men and newborns registered in the Electronic Data Entry Forms (EDEF) started in 2011. The Association inspires young scientists and clinical researchers for creative thinking, and helps to learn how to make decision on “publish and disclose” or “publish and protect”. RECOOP provides training for young scientists to learn proper and scientifically sound communication of their research results in their manuscripts and presentation. The Association provides practical training on the presentation of data in the manuscript from the “Introduction, Methods, Results and Discussion” to the “Conclusion” sections of the manuscript and guides the young scientists how to organize data in tables and graphs, presenting results of statistical analysis. The RECOOP HST Association organizes annually the Bridges in Life Sciences Conferences to review the scientific progress in the Association. During the Bridges in Life Sciences Annual Meeting the Scientific Advisory Board selects the top ten young scientists.

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The RECOOP scientific works were published in the Annual Scientific Review Journal the Biopolymers and Cell (www.biopolymers.org.ua) 2010. Vol. 26. N 2 & N 2 supplementary; 2011. Vol. 27. N 2 & N 2 Supplementary; 2012. Vol. 28. N 2 supplementary and 2013.Vol. 29. N2 supplementary. The winner gets the Cedars – Sinai RECOOP Scholar Grant to visit Los Angeles for two weeks with her/his supervisor. They are visiting research groups and laboratories and presenting their scientific work during research seminars. The top ten young scientists selected during the Bridges in Life Sciences Annual Conferences have the opportunity to apply for International Visegrad Fund (IVF) Scholarship and receive the RECOOP Young Scientists Matching Fund. The Visegrad Scholarship is the Visegrad Four European Macro-Region’s Fulbright Program. Therefore it could be important to link the Visegrad Scholarship and the Fulbright Foreign Student Program. CSMC – RECOOP Research Centers (CRRC) the Center of Excellences of the RECOOP HST Association. They host young scientists, Ph.D. students with CSMC – RECOOP (IVF – CSMC - RECOOP) Scholarship. The RECOOP HST Association Scientific Advisory Board selects the young scientists could compete for IVF – CSMC - RECOOP Scholarship. The selected young scientists (preferably Ph.D. students) will spend maximum four semesters receive: €2,300 / semester and the corresponding host universities/institutes receive €1,500/semester/scholar. The host CRRC will get €1,000 for laboratory expense and consumables from CSMC – RECOOP HST Association. RECOOP activities compliment the U.S. Government’s commitment to the Global Health Initiative “the way U.S. Government agencies conduct global health activities, building on successful bipartisan leadership in global health and expanding their impact for sustainable results around the world.”

“The RECOOP HST Association explores and enhances LOCAL scientific outputs of the partner organizations, creates critical mass of scientifically sound innovative research at REGIONAL level and exploits the research outcomes at GLOBAL level to improve the prevention and treatment of major public health problems.” TM

The RECOOP Research Networks could be a model for geographical regions have lingual, cultural, historical, economic and political common ground worldwide in regions in Africa, Asia, North and South America to improve women’s and children’s health. Dr. Sandor G. Vari, MD Director, International Research and Innovation Management Program Cedars-Sinai Medical Center & President of the RECOOP HST Association 6420 Wilshire Blvd., Ste. 300, Los Angeles, CA 90048-5502, USA Office 1: 1 323-866-8122; 1 323-866 -6824 Office 2: 1 818 904 1954 Mob: 1 818 398-2642 E-mail: [email protected]

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Preconference Workshop – „Protect and Publish“

Communication is not something added onto science - it is the essence of science.

“Clear Thinking = Clear Writing”

Significance, Impact, Innovation are vital to scientific and medical writing! Capacity building for innovation, science communication and grant writing for young scientists in Central and Eastern Europe (CEE) Preconference Workshop on May 28 and 29 in HOTEL DUJAM *** & YOUTH HOSTEL web:www.hoteldujam.com. For the Workshop arrival on May 27 (Wednesday), 2014 and the workshop will be on May 28 and 29. The participating young scientists will stay in that hotel during the Bridges Conference since they are invited to attend the RECOOP 9th Annual Scientific Conference. The Bridges in Life Sciences 9th Annual Conference will follow on May 30 (Friday) from 8:30 to 1:00 pm and May 31 (Saturday) from 9:00 to 6:00 pm in Hotel Atrium Domovinskog rata 49a, 21000 Split, Croatia http://www.hotel-atrium.hr/en/ 1., Aims:

RECOOP HST Association implements Science and Innovation Capacity Building (SCICAB) program as part of the RECOOP Protect and Publish (P&P) Strategy for innovation management, science communication and grant writing in the Central and Eastern European Countries. The objectives of SCICAB are to increase the number of young scientists capable to make decision in protect and publish, able to write good quality manuscripts in peer review journals and competitive grants.

2., Goals

RECOOP HST Associations’ main goal is to build multinational, multidisciplinary collaboration and establishes long term life sciences research and public health program in seven Central and Eastern European (CEE) countries; Croatia, Czech, Hungary, Poland, Romania, Slovak, and Ukraine. Research results need to be published to become accessible and contribute to the progress of research and patient care. Publishing of the scientific outcomes it is necessary but protecting the intellectual property rights is crucial to convert the results into products: laboratory tests, diagnostic and treatment modalities. Inventors should reinvest the patent income into the innovators’ research facilities and reward scientists too. The ability to write well is critical for healthcare professionals and researchers to precisely convey their ideas and research results.

3., Methods The participating young scientists with help of the tutors will convert their abstracts were written to present their research at the 9th Bridges in Life Sciences Conference in Split, Croatia, May 2014 into a manuscript and those will be scrutinized and discuss to study the most important aspects of writing research articles. The same method will be used for the grant writing. Tutors will help them to learn how to make decision on protect & publish.

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Faculty: Prof. Ana Marusic, MD, PhD Chair, Department of Research in Biomedicine and Health Co-editor in Chief, Journal of Global Health, www.jogh.org University of Split School of Medicine, Split, Croatia Brenda Edin and Michael Baker Baker Group LLP, A Technology Advancement Company, Portland, Oregon, USA dr. TamásBene Legal advisor, Knowledge and Technology Transfer Office University of Debrecen, Hungary Vladimir Yossifov Consultant, IP Services Managing Director, HTSI SA Geneva, Switzerland Kristin Martinez Manager, International Relations, Technology Transfer Office Cedars-Sinai Medical Center Sandor G. Vari, MD Director, International Research and Innovation Management Program Cedars-Sinai Medical Center, Los Angeles, CA, USA & President of the RECOOP HST Association Workshop – Protect and Publish May 28, 2014 Day 1 – Wednesday – Publish - Manuscript Writing

8:30 Welcome and introductions – Sandor G. Vari

8:45 Communicating results of scientific research – Ana Marušić

9:30 Are there differences in communicating science among different scientific fields? –

Anan Marušić

10:15 Coffee break

10:30 Structure of the scientific article: Writing articles in Life Sciences – Team of Ana

Marušić

11:15 Structure of the scientific article: Introduction and Discussion - Team of Ana Marušić

12:00 Structure of the scientific article: Methods and Results - Ana Marušić

13:00 Lunch break

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14:45 Around IMRAD: title, abstract, acknowledgments, disclosures, references – Ana

Marušić

15:30 Ethics in scientific publications, case studies in publication ethics - Team of Ana

Marušić

16:00 Coffee break

16:15 Preselected young scientists (three) published their work in the Croatian Medical

Journal (April 2014) RECOOP Special issue will present their work in brief (max 15

minutes) oral presentation.

Senka Blažetić, Department of Biology, University J. J. Strossmayer Osijek Rostyslav Panchuk, Department of Regulation of Cell Proliferation and Apoptosis, Institute of Cell Biology NAS of Ukraine, Lviv, Ukraine

17:00 Lecturers and students will discuss the structure and delivery of the presentation. –

Team of Ana Marušić

18:30 Close of the day: Questions and answers - Ana Marušić

19:00 Dinner Round Table: Scientific article – is it difficult to write a scientific paper?

Moderator: Team of Ana Marušić

May 29, 2014 Day 1 – Thursday – Protect 8:30 Welcome and introductions – Sandor G. Vari 8:45 Reasons and ways to protect research results before publication – Tamas Bene 9:30 The importance of intellectual property (IP) management at universities and public

research organizations (PRO).– Tamas Bene 10:15 Coffee break

10:30 Patent Cooperation Treaty as an umbrella for patenting - Vladimir Yossifov 11:15 Market analysis, planning – Baker Group

12:00 Market-based IP valuation – Baker Group

13:00 Lunch break

14:45 Licensing, product development direction - Baker Group

15:30 Case study – Baker Group

16:00 Coffee break

16:15 Funding opportunities in Central and Eastern Europe – Sandor G. Vari

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17:00 EU – FP8 – Horizon 2020 – Sandor G. Vari

18:30 NIH Grant types – Kristin Martinez

19:00 Dinner Round Table: Who could write grants – Sandor G. Vari

Summary of RECOOP Protect and Publish Workshop PUBLISH COMMUNICATING RESULTS OF SCIENTIFIC RESEARCH - Anan Marušić Scientific and medical journal editors and peer reviewers continually point out that unclear writing is one of the most important reasons for article rejection. Stated another way, anything that gets between the writer’s scientific message and the reader’s comprehension of that message, derails the paper and upsets the reviewers. Unclear writing signals unclear thinking. To write clearly, authors need to understand all the nuances and aspects of the subject before they begin wordsmithing the article. Writing down the ideas even in an outline form helps to clarify thinking. Scientists tend to imitate the academic, obscure writing that is seen in some scientific journals and in grants, attempting to impress the reader with complex, long and unclear phrases and paragraphs. If authors want to write more clearly, let go of this style and develop your own clear way of communicating. They should always think of the reader who needs to understand what authors are intending to communicate. The workshop designed to help young scientists and medical professionals to understand the root of poor writing, identify red flags within their own writing style, and design clear, concise, powerful pieces that meet the requirements of the most demanding audiences within their professional careers. The training includes:

Discussion of the differences in science communication in different scientific fields. The basic writing principles that authors actually know but forget during manuscript writing. Underline the power of conciseness, saying more with less. Redundancies in writing: why repetition is not always a good thing. How to keep reviewers’ focus on science, and not on the grammar

The faculty and participating young scientists will have writing exercises to get authors on the path to becoming a “Successful Author”:

The structure of articles in Life Sciences Introduction and Discussion Methods and Results Around IMRAD: title, abstract, acknowledgments, disclosures, references

The faculty also will discuss “Ethics in Scientific Publications” and will have case studies in publication ethics.

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PROTECT REASONS AND WAYS TO PROTECT RESEARCH RESULTS BEFORE PUBLICATION – Tamas Bene Dissemination of scientific knowledge through publication is one of the most common and rapid instruments. Publishing, however, is not always as timely as it may appear as the peer review process can delay the final article publication. The protection granted by the IP system to an article or publication is copyright, which arises automatically when the researcher writes it. However, copyright is not the right tool to exploit inventions commercially. If the research activities result in a promising practical innovation, researchers should consider applying for a patent in order to commercially exploit the invention and have in return revenues. Patenting and publishing do not exclude each other, but the right order of these activities is critical. Patenting always should be done first. The lecture will give an overview on various IP forms and explain the basics of the patenting procedure. THE IMPORTANCE OF INTELLECTUAL PROPERTY (IP) MANAGEMENT AT UNIVERSITIES AND PUBLIC RESEARCH ORGANIZATIONS (PRO) –Tamas Bene More and more universities and public research organizations recognize the need for encouraging the practical application and economic use of the results of research carried out at the institution for the benefit of the general public. To achieve this goal, these institutions need to define intellectual property broadly, and their policies need to be comprehensive in their coverage. Depending on the direction of R&D activities, each institution should decide on the type of intellectual property (IP) to be included in its IP policy. A good IP policy deals with all aspects of IP management: it provides legal certainty in research activities and technology-based relationships with third parties and sets out the procedures on the identification, ownership, protection and commercialization of Intellectual Property. It also ensures that economic benefits arising from the commercialization of the IP are distributed in a fair and equitable manner that recognizes the contributions of all stakeholders. The session will give an overview on university IP management and explain the basics of technology transfer activities. PATENT COOPERATION TREATY AS AN UMBRELLA FOR PATENTING - Vladimir Yossifov The Patent Cooperation Treaty or PCT is an international agreement for filing patent applications having effect in up to 117 countries. Although the PCT system does not provide for the grant of an international patent, the system:

• simplifies the process of filing patent applications • delays the expenses associated with applying for patent protection in other countries • allows the inventor more time to assess the commercial viability of his/her invention.

Under the PCT, inventors can file a single international patent application in one language with one patent and simultaneously seek protection for an invention in up to 117 countries throughout the world. MARKET ANALYSIS AND PLANNING – Baker Group Early market research is key to determining whether an innovation can and should be translated from scientific study to a commercial product. In addition to understanding the technology, researchers interested in creating a viable business opportunity must be able to

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identify, anticipate and satisfy consumer needs – all while making a profit. External market validation through stakeholder input and published data about products, markets and brands, are key data points in the decision making process. MARKET-BASED IP VALUATION – Baker Group Estimating the potential for IP to produce future revenue is at the core of determining the value of a patent. Market-based valuation of intellectual property heavily considers competitive products, consumer need and cost. Within the medical sectors, the ability to reduce healthcare costs and improve patient outcomes are key value considerations. LICENSING & PRODUCT DEVELOPMENT – Baker Group By understanding the key tenants and terms of a licensing agreement, one can determine how commercial development may be positively or negatively impacted. With this knowledge, inventors can identify licenses that will enhance innovation and create viable business opportunities. CASE STUDY – Baker Group The team at Cedars-Sinai Regenerative Medicine Institute is developing a minimally invasive spinal injection device for the treatment of Amyotrophic Lateral Sclerosis (ALS). Current surgical spinal devices are difficult to use, have an excessive part count and have problems related to precise positioning. The device being developed at Cedars-Sinai is intended to safely, accurately and securely deliver therapeutic agents into the spinal cord, brain, and/or joints. The first prototype is being developed for use in pre-clinical trials this year and is expected to be commercialized for future use for this and other spinal injection applications. PROTECT – IP PROTECTION, MARKET VALUE & TECHNOLOGY TRANSFER – Baker Group Prior to publishing or publicly disclosing information researchers must protect intellectual property in order for IP to have commercial value. Within the business sector, only well-protected IP is considered for future development. Adhering to an organized, intentional technology transfer process is of benefit to all involved in the process of commercializing IP. FUNDING OPPORTUNITIES IN CENTRAL AND EASTERN EUROPE – Sandor G. Vari The RECOOP HST Association’s main goal is to enhance research collaboration and provide platforms for scientific networking in life sciences within the Visegrad Four Countries, Central - Eastern Europe, and Western Balkan. The research priority of the Association is women's and child’s health in the Visegrad Four European Macro-Region (Czech Republic, Hungary, Poland and Slovakia) and the neighboring countries (Belarus, Bosnia and Herzegovina, Croatia, Moldova, Macedonia, Montenegro, Romania, Serbia and Ukraine). The RECOOP HST Association is using grant opportunities of International Visegrad Fund (IVF) http://visegradfund.org/ to organize scientific meetings and workshops. The IVF is the only institution of the Visegrad co-operation established in 1999 and headquartered in Bratislava. The budget of IVF made by the Council of Ministers formed from the prime ministers of the Visegrád Group, also called the Visegrád Four or V4 (Czech Republic, Hungary, Poland and Slovakia). The grant opportunities are Small, Standard and Strategic Grants, scholarships and artist residencies.

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EU – FP8 – HORIZON 2020 – Sandor G. Vari The research collaborations become increasingly complex and requiring integration of knowledge, data and resources by way of transnational collaboration. The RECOOP HST In the next years RECOOP Association will apply for selected EU HORIZON2010 calls therefore, it is important to provide information for the RECOOP members about the legal basis and rules of participation, the Framework Programme H2020, the Health Programme 2014-2020 and the upcoming programs in 2014-2015:

PHC – 1 Understanding health, ageing and disease PHC-03-2015 Understanding common mechanisms of diseases and their relevance in co-morbidities PHC-11-2015 Development of new diagnostic tools and technologies: in vivo medical imaging technologies

NIH GRANT TYPES – Kristin Martinez

The National Institutes of Health (NIH), a part of the US Department of Health and Human Services, is the medical research agency for the US. Made up of 27 Institutes and Centers, each with their own area of concentration, the NIH uses different grant types to focus and fund research. By understanding the common types of research grants, international investigators will be able to plan and organize their research application whether they apply for NIH funding directly or as part of collaboration (subcontract) with a US research team.

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Agenda of the Bridges in Life Sciences 9th Conference May 29 – June 1, 2014

Partially sponsored by the International Visegrad Fund Standard Grant: ID 21320181 Venue: ATRIUM HOTEL 16:00 – 19:30 Registration and poster installation in the following sessions:

Mother and Child Health Cardiovascular Diseases Stress, Obesity and Metabolic Diseases Neurological Disorders and Brain Research Cancer Research NanoBioTechnology Translatonal Research

Poster size is the following: width 90 cm x height 120 cm. The posters reviewed and discussed throughout of the Conference and poster room will be open: May 30 (Friday) from 8:30 to 19:00 May 31 (Saturday) from 9:00 to 19:00 The posters have to remove on May 31 (Saturday) from 19:00 20:00 Buffet Dinner

Agenda of Conference on May 30 (Friday), 2014 9:00 to 10:30 Plenary Session

9:00 Opening Remarks

Edward Prunchunas Senior Vice President for Finance and Chief Financial Officer, Cedars-Sinai Medical Center, Los Angeles, CA, USA and Chairman of the Supervisory Board of the RECOOP HST Association

9:15 Review of the Research Activities in the RECOOP Sandor G. Vari, M.D. Director, International Research and Innovation Management Program Cedars-Sinai Medical Center, Los Angeles, CA, USA & President of the RECOOP HST Association

9:30 Keynote Speaker: Biomedical Innovation at Cedars – Sinai Medical Center Shlomo Melmed, M.D. Senior Vice President, Academic Affairs, Dean of the Medical Faculty, Cedars-Sinai Medical Center, Los Angeles, CA, USA

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10:00 Protect – IP Protection, Market Value and Technology Transfer

Michael Baker Baker Group LLP, A Technology Advancement Company, Portland, OR, USA

10:30 Coffee break 10:30 – 12:00 Poster Session Poster presentation: 5 minutes explanation and 3 minutes discussion

Session Chairs Calvin J. Hobel Marija Heffer Daniel Horak

Ratio of cord to maternal serum PCB concentrations in relation to their congener-specific physicochemical properties Kinga Lancz Department of Environmental Medicine, Slovak Medical University, Faculty of Public Health Electromyographic investigation on pregnant rat uterus in vivo Kálmán Szűcs Department of Pharmacodynamics and Biopharmacy, University of Szeged, Hungary Cardiosphere-derived cell exosomes stimulate cardiomyocyte proliferation and angiogenesis in vitro, and improve functional recovery post myocardial infarction in mice Ahmed Ibrahim Heart Institute, Cedars – Sinai Medical Center, Los Angeles, California, USA Cell-based quantum dot labeling of RANK-mediated signaling mediators predicts survival of patients with prostate cancer Haiyen E. Zhau Louis Warschaw Prostate Cancer Center, Cedars – Sinai Medical Center, Los Angeles, California, USA Chelidonine interferes with IL-6R/STAT3 signaling in uveal melanoma cells Eniko Nizsaloczki Department of Biophysics and Cell Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

11:00 – 12:30 Plenary session

Oral presentation timed strictly for 12 minutes! Session Chairs

Livia Puljak William J. Britt

Artur Podhorodecki Antenatal Maternal and Fetal Steroid Treatment: Neonatal Outcome

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Tibor Ertl, Department of Neonatology, School of Medicine, University of Pécs, Hungary Acute stress and female hormones alter cardiomyocyte contractile function in ovariectomized rats Attila Borbély University of Debrecen, Faculty of Medicine, Institute of Cardiology, Division of Clinical Physiology, Debrecen, Hungary Influence of body weight and body composition on bone mineral content and density in female rats with and without ovariectomy Patrícia Kramárová Department of Toxicology, Slovak Medical University in Bratislava; 2Department of Clinical and Experimental Pharmacotherapy, Slovak Medical University in Bratislava, Slovakia GAP-43 as a potential marker of neuronal stress - in vivo imaging and immunofluorescence study applied on ischemic brain lesion Srećko Gajović Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia Polymeric nanobioconjugates for cancer treatment Julia Y. Ljubimova Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California, USA Section-specific determination of smooth muscle activity by smooth muscle electromyography in normal and immobilized rats Robert Gaspar Department of Pharmacodynamics and Biopharmacy, University of Szeged, Hungary

Q&A and Panel Discussion (15 minutes) 12:30 – 14:00 Buffet Lunch 14:00 – 16:00 Plenary session

Oral presentation timed strictly for 12 minutes! Session Chairs Rostyslav Stoika

Jan Pitha Leland Chung

Perinatal hypoxia: Different effects of the inhibitors of GABA transporters GAT1 and GAT3 on the initial velocity of [3H]GABA uptake by cortical, hippocampal and thalamic nerve terminals Tatiana Borisova Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine,

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Contribution of myofilament protein carbonylation t o systolic and diastolic dysfunction Zoltán Papp University of Debrecen, Faculty of Medicine, Institute of Cardiology, Division of Clinical Physiology, Debrecen, Hungary Impact of ovariectomy, high fat diet and lifestyle modifications on oxidative/antioxidative status in rat liver Rosemary Vuković Department of Biology, J. J. Strossmayer University of Osijek, Osijek, Croatia Alginate a stabile and biocompatible stem cells-seeded hydrogel carrier for the targeted delivery in the stroke lesion Lejla Ferhatovic Hamzic Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Croatia RANK- and c-Met-mediated feed forward signal network promotes metastasis by recruiting dormant cells and predicts the survival of prostate cancer patients Leland WK Chung Zhau, Departments of Medicine, and Surgery, Uro-Oncology Research Program, Cedars-Sinai Medical Center, Los Angeles, CA, USA A pilot study applicability of standardized modified method of dry (throat/buccal) swabs in PCR diagnosis of enteroviral infections Shubhada Bopegamage Enterovirus Laboratory, Slovak Medical University, Bratislava, Slovak Republic

Q&A and Panel Discussion (15 minutes)

16:00 – 16:30 Coffee Break 16:00 – 18:00 Poster Session

Poster presentation: 5 minutes explanation and 3 minutes discussion

Session Chairs Julia Y. Ljubimova

Shubhada Bopegamage Robert Gaspar

Characteristics of autoimmune diseases in patients from Osijek- Baranja County (Croatia) – a population study Martina Mihalj Department of Physiology and Immunology, School of Medicine, University J. J. Strossmayer Osijek, Croatia Androgenic effect of honeybee drone milk in castrated rats Adrienn Seres Department of Pharmacodynamics and Biopharmacy, University of Szeged, Hungary

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Cardiovascular and cerebrovascular complications in rheumatoid arthritis patients at Osijek Baranja County (Croatia) Sanja Novak Department of Physiology and Immunology, School of Medicine, University J. J. Strossmayer Osijek, Croatia Lifestyle intervention in general practice for physical activity, smoking, alcohol consumption and diet in elderly Davorka Vrdoljak Department of Family Medicine, University of Split School of Medicine, Split, Croatia Impact of adipose tissue inflammation in the pathogenesis of atherosclerosis Anna Králová Laboratory for Atherosclerosis Research, Institute of Clinical & Experimental Medicine (IKEM), Prague, Czech Republic Prevalence of cardiovascular complications in three age groups of patients with Systemic Lupus Erythematosus (SLE) Zrinka Mihaljevic Department of Physiology and Immunology, School of Medicine, University J. J. Strossmayer Osijek, Croatia Cutaneous expression of calcium/calmodulin-dependent protein kinase II following diabetes induction Antonia Jelicic Kadic Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia The differentiation of SH-SY5Y neuroblastoma cells – the effect of the antidepressants Zsófia Ulakcsai Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary The expression of calcium/calmodulin-dependent protein kinase II in spinal cord in rat models of type 1 and type 2 diabetes Matija Boric Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia Validation of an aminonaphthalene trisulfonate labeled N-glycan database by CGE Csaba Váradi carries for Márta Kerékgyártó Horváth Laboratory of Bioseparation Sciences, MMKK, University of Debrecen, Debrecen, Hungary In vivo bioluminescent imaging of inflammation dynamics after different MCAO periods Dora Polšek

University of Zagreb School of Medicine, Croatian Institute for Brain Research - Zagreb, Croatia

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Functionalized core-shell porous silica/maghemite nanoparticles: Design, synthesis and immunotoxicity Beata Zasonska Department of Polymer Particles, Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic RECOOP consortium – promising platform for new grant opportunities Jana Tulinská Department of Immunology and Immunotoxicology, Department of Biology, Slovak Medical University, Bratislava, Slovakia Functionalization of quantum dots with PEG dervatives – a versatile approach for obtaining water soluble fluorescent nanomarkers Anna Żelazo Institute of Physics, Wroclaw University of Technology, Institute of Physics, Wroclaw, Poland

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RECOOP HST Association General Assembly 16:30 – 18:00

Cedars – Sinai Medical Center, Los Angeles, USA Edward Prunchunas, CSMC and Sandor G. Vari, CSMC - RECOOP School of Medicine University J. J. Strossmayer Osijek, Croatia Authorized Representative IKEM - Institute for Clinical and Experimental Medi cine, Prague, Czech Republic Jan Pitha Institute of Macromolecular Chemistry Academy of Sciences, Czech Republic Daniel Horák Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic Vanda Bostik Faculty of Pharmacy, University of Copenhagen, Denmark S. Moein Moghimi University of Debrecen, Hungary Laszlo Matyus University of Pecs, Hungary Tibor Ertl University of Szeged, Hungary Gyorgy Falkay Carol Davila University of Medicine and Pharmacy, Bucharest, Romania Iuliana Ceausu Slovak Medical University, Bratislava, Slovakia: Authorized Representative Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine Tatiana Borisova, Palladin Institute of Biochemistry NAS of Ukraine Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine Rostyslav Stoika Danylo Halytsky Lviv National Medical University, Lviv, Ukraine Roman Lesyk and/or Oleh Pinyazhko Invited:

Elizabeta Has-Schön, Department of Biology, University J.J. Strossmayer Ivančica Pavličević, Family practice office, Split, Croatia Artur Podhorodecki, Wroclaw University of Technology, Institute of Physics, Wroclaw, Poland

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18:00 – 19:30 Plenary session Oral presentation timed strictly for 12 minutes!

Session Chairs

Tatiana Borisova Gyorgy Falkay Roman Lesyk

Allostatic Load Score Defines the Percent of Women who are Biochemically & Physiologically “Unhealthy” during the Postpartum Period. Implications for reducing the Risk of Cardiovascular Disease. Calvin Hobel Department of Obstetrics, Gynecology, Cedars Sinai Medical Center, Los Angeles, CA, United States Nanoparticle-Mediated Tumour Growth: Cause for Reflection S. Moein Moghimi Centre for Pharmaceutical Nanotechnology and Nanotoxicology, Department of Pharmacy, University of Copenhagen, Copenhagen Ø, Denmark Changes in Cardiovascular Risk Profile in Women after Menopause (Prague Pre- and Post-Menopausal Female Study) Jan Pitha

Laboratory for Atherosclerosis Research, Institute of Clinical & Experimental Medicine, Effects of high fat diet, ovariectomy and physical activity on leptin receptor expression in rat brain and white fat tissue Senka Blažetić Department of Biology, University of Osijek, Osijek, Croatia Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study Rostyslav Panchuk Institute of Cell Biology National Academy of Sciemces of Ukraine, Lviv, Ukraine A comparative study of neurotoxic potential of synthesized polysaccharide-coated and native ferritin-based magnetic nanoparticles Arsenii Borysov Palladin Institute of Biochemistry National Academy of Sciemces of Ukraine, Kiyv, Ukraine

Q&A and Panel Discussion (15 minutes) 19:30 Buffet Dinner

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Agenda of Conference May 31 (Saturday), 2014

8:30 - 10:15 Plenary session Oral presentation timed strictly for 12 minutes!

Session Chairs

S. Moein Moghimi Srećko Gajović

Zoltan Papp Enhanced anticancer activity and circumvention of drug resistance mechanisms by novel polymeric/phospholipidic nanocarrier Rostyslav Stoika Institute of Cell Biology National Academy of Sciences of Ukraine, Lviv, Ukraine Preterm Birth and its consequences in rural and urban communities of India Chander P Arora, International Research and Innovation Management, Cedars-Sinai Medical Center; Los Angeles, CA, USA The influence of selected factors of life style on bone health – the experimental study Zora Krivošíková Department of Clinical and Experimental Pharmacotherapy, Slovak Medical University in Bratislava, Slovakia SSAO enzyme activity in adjuvant arthritis and anti-inflammatory effect of a new SSAO inhibitor Tamás Tábi Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary Transcatheter Patent Ductus Arteriosus Closure in VLBW Infants Charles F. Simmons, Jr., Department of Pediatrics, Cedars – Sinai Medical Center, Los Angeles, CA, USA N-Glycan mapping by capillary electrophoresis Andras Guttman MTA-PE Translational Glycomics Research Group, University of Pannonia, Veszprem, HU

Q&A and Panel Discussion (15 minutes)

10:15 Coffee break 10:30 – 11:30 Poster Session

Poster presentation: 5 minutes explanation and 3 minutes discussion

Session Chairs Iuliana Ceausu Jana Tulinska

Charles F. Simmons

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Research Achievements (2013-2014) of the Department of Regulation of Cell Proliferation and Apoptosis at the Institute of Cell Biology (NAS of Ukraine) Due to Collaboration Network Within the RECOOP-HST Association and Collaboration with Other None-RECOOP Institutions Rostyslav R. Stoika Institute of Cell Biology National Academy of Sciences of Ukraine, Lviv, Ukraine Experimental esophagitis research: new insight on animal models and translational aspects Oksana Zayachkivska Physiology Department, Lviv National Medical University, Lviv, Ukraine Cervical fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor rupture of membranes Daniel Lesko carries Ivana Musilova Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine Hradec Kralove, Czech Republic How does maternal smoking influence the early neurobehavioral development of rat pups? Barbara Mammel Department of Obsterics and Gynecology and Department of Anatomy, Medical Faculty, University of Pécs, Hungary The renin release in ischemia/reperfusion kidney injury; gender differences Anna Kosik 1st Department of Pediatrics, Semmelweis University Budapest, Hungary Microalbuminuria and cardiometabolic risk factors in general population of high school students Radana Kollarova Institute of Molecular BioMedicine, Medical Faculty, Comenius University, Bratislava, Slovakia Diabetes –induced impairments of the exocytosis process and the effect of gabapentin: the link with cholesterol level in neuronal plasma membranes Irene Trikash Department of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine The role of musashi in Caenorhabditis elegans – the gene of forgetting? Gábor Bánk Fenyves Department of Medical Chemistry, Semmelweis University, Budapest, Hungary 11:30 - 12:30 Plenary session

Session Chairs András Guttman

Shubhada Bopegamage Chander P. Arora

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Value of hysteroscopy for endometrium evaluation in postmenopause Iuliana Ceausu “Carol Davila” University of Medicine and Pharmacy, “Dr. I. Cantacuzino” Department of Obstetrics and Gynecology, Bucharest, Romania Gender difference in expression of receptors for steroid hormones and leptin in adrenal gland after chronic and acute stress Marta Balog

Department of Medical Biology, Laboratory of Neurobiology, J. J. Strossmayer University of Osijek, School of Medicine, Osijek, Croatia 5-Ylidene-4-thiazolidinones anticancer agents’ source: problem solution Roman Lesyk Department of Pharmaceutical, Organic and Bioorganic Chemistry, Danylo Halytsky Lviv National Medical University Visualization of melanoma tumor with lectin-conjugated rare-earth nanocrystals Artur Podhorodecki Wroclaw University of Technology, Institute of Physics, Wroclaw, Poland

Q&A and Panel Discussion (15 minutes) 12:30 – 14:00 Buffet Lunch 14:00 - 15:00 Plenary session – RECOOP Review 14:00 – 14:30 Standard Operating Procedures for CRSMN at the RECOOP HST

Association Linn Defensor RN, MSHS-CRA, CCRP

Office of Research Compliance and Quality Improvement, Cedars-Sinai Medical Center, Los Angeles, CA, USA & Global Clinical Trial Leader, CRSMN, RECOOP HST Association

14:30 – 15:00 RECOOP Future Activities

Grants – NIH, EU Horizon and IVF Meetings: 5th TriNet Meeting, 10th Anniversary Bridges Scientific Conference

Q&A and Panel Discussion (15 minutes) 15:00 - 16:00 Breakaway sessions (The sessions will be in different rooms)

Mother and Child Health Chander P. Arora Women’s Health and Cardiovascular Diseases Zoltan Papp NanoBioTechnology Rostyslav Stoika

16:00 – 16:30 Coffee Break

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16:00 – 18:30 Closing Poster session

Poster presentation: 5 minutes explanation and 3 minutes discussion

Chairs Éva Szökő

Zora Krivosikova Tibor Ertl

Risk factors for preterm birth in Southern Croatia: a case control study at University Hospital Tanja Vukušić-Pušić Department of Obstetrics and Gynaecology, University Hospital Split, Croatia Detection of novel auto-antigens in patients with recurrent miscarriage: Description of an approach and preliminary findings Rostyslav Stoika carries for Yuriy Y. Kit Institute of Cell Biology National Academy of Sciemces of Ukraine, Lviv, Ukraine Cervical fluid IL-6 and IL-8 levels in pregnancies complicated by preterm prelabor rupture of membranes Martin Stepan Department of Obstetrics and Gynecology, Charles University in Prague, Faculty of Medicine Hradec Kralove, Czech Republic Risk factors and clinical follow-up of patients with preterm births in a tertiary referral maternity unit in Bucharest, Romania Cristian Poalelungi ”Carol Davila” University of Medicine and Pharmacy, Bucharest, ”Dr. I. Cantacuzino” Hospital, Department of Obstetrics and Gynecology, Bucharest, Romania The Role of PACAP on Retinal Vascular Changes in the Rodent Model of Retinopathy of Prematurity Timea Kvarik Dept of Anatomy MTA PTE “Lendulet” PACAP Research Team and Dept of Obstetrics and Gynecology, University of Pecs, Pecs, Hungary Shared decision making in life style and nutrition for intervention in women with risk factors in cardiovascular health Ivančica Pavličević Department of Family Medicine, University of Split School of Medicine Astrocyte toxicity to motor neurons is dependent on age Melanie M. Das The Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA Synthesis and surface functionalization of NaGdF4:Yb3+,Er3+ nanocrystals for their biomedical applications

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Agnieszka Noculak Institute of Physics, Wroclaw University of Technology, Wroclaw, Poland Haptoglobin N-glycome Alteration Analysis of Inflammatory and Malignant Lung Diseases by Capillary Electrophoresis Csaba Váradi Horváth Laboratory of Bioseparation Sciences, University of Debrecen, Hungary Study protocol for the project Coxsackievirus infections during pregnancy Shubhada Bopegamage Enterovirus Laboratory, Slovak Medical University, Bratislava, Slovak Republic Genotyping and characterization of Varicella zoster clinical isolates from Hradec Kralove, Czech Republic Monika Schmidt Centre of Advanced Studies, FMHS, University of Defence, Hradec Kralove, Czech Republic Entero-salivary nitrites recirculation is an endogenous modulator of leukocyte-mediated inflammation in experimental oesophagitis Irena Pshyk-Titko Physiology Department, Lviv National Medical University, Lviv, Ukraine 18:30 – 19:30 Plenary session – Closing Remarks

RECOOP Research Networks – project plan

Mother and Child Health Chander P. Arora Women’s Health and Cardiovascular Diseases Zoltan Papp NanoBioTechnology Rostyslav Stoika Overview of the RECOOP Association’s General Assembly Sandor G. Vari

19: 30 - 22:00 Buffet Dinner

June 1, 2014 (Sunday) Departure