PrecisionPediatrics:a Bridge towards

the Future

8/10 March 2019

Spazio eventiCastiglioneFlorence President

Vassilios Fanos

Galileo Advanced Course on Pediatrics

WITH THE PATRONAGES OF

FRIDAY 8 MARCH 2019

INTRODUCTION TO THE COURSE

14.00-14.15 Where are we now? Vassilios Fanos (Cagliari, Italy)

14.15-14.30 The newborn at the center of future Fabio Mosca (Milan, Italy)

MODULE 1. INNOVATION: EVOLUTION-REVOLUTION Chairperson: Apostolos Papageorgiou (Montreal, Canada)

14.30-15.00 Perinatal programming: from the womb to the adult Vassilios Fanos (Cagliari, Italy)

15.00-15.30 Asphyxia in the next future: the value of metabolomics Ola D. Saugstad (Oslo, Norway)

15.30-16.00 Omics in perinatology Vassilios Fanos (Cagliari, Italy)

16.00-16.30 Pollution and maternal milk Kadriye Yurdakok (Ankara, Turkey)

16.30-16.50 Discussion of the previous topics

FRIDAY 8 MARCH 2019

MODULE 2. TOP RESEARCH BEDSIDE Chairperson: Federico Mecacci (Florence, Italy)

17.10-17.40 Perinatal Care at the confluence of humanistic and scientific paradigms Gian Paolo Donzelli (Florence, Italy)

17.40-18.10 Patent ductus arteriosus: ibuprofen or paracetamol? Carlo Dani (Florence, Italy)

18.10-18.40 Precision respiratory assistance in the newborn Corrado Moretti (Rome, Italy)

18.40-19.10 Gender medicine in pediatrics Murat Yurdakok (Ankara, Turkey)

19.10-19.30 Discussion of the previous topics

SATURDAY 9 MARCH 2019

MODULE 3. BUGS, SUPERBUGS... AND MORE Chairperson: Ariadne Malamitsi-Puchner (Athens, Greece)

08.00-08.30 Biomarkers of sepsis: from CRP to metabolomics Michele Mussap (Genoa, Italy)

08.30-09.00 Microbiomics in pediatrics Vassilios Fanos (Cagliari, Italy)

09.00-09.30 Pre- and probiotics in pediatrics Johan Garssen (Utrecht, The Netherlands)

09.30-10.00 Bronchiolitis: the same old story? Diego Peroni (Pisa, Italy)

10.00-10.30 New frontiers in immunology Chiara Azzari (Florence, Italy)

10.30-10.55 Discussion of the previous topics

SATURDAY 9 MARCH 2019

MODULE 4. BRAIN AND MIND Chairperson: Ola D. Saugstad (Oslo, Norway)

11.00-11.30 Pediatrics today and tomorrow Murat Yurdakok (Ankara, Turkey)

11.30-12.00 Neuroprotection: what’s new? Giuseppe Buonocore (Siena, Italy)

12.00-12.30 Autism: what are we missing? Paolo Curatolo (Rome, Italy), Antonio Noto (Cagliari, Italy)

12.30-12.50 Discussion of the previous topics

Module 5. GUT, THE SECOND BRAIN Chairperson: Gian Paolo Donzelli (Florence, Italy)

14.00-14.30 Necrotizing enterocolitis: changing perspectives Ariadne Malamitsi-Puchner (Athens, Greece)

SATURDAY 9 MARCH 201914.30-15.00 Old problems, new fortifiers Enrico Bertino (Turin, Italy)

15.00-15.30 News on research in pediatric nutrition Johan Garssen (Utrecht, The Netherlands)

15.30-16.00 Abnormal gut permeability in gastrointestinal (GI) and extra-GI diseases (leaky gut syndrome) Ruggiero Francavilla (Bari, Italy)

16.00-16.30 Aggression in children: the twins lesson Dorret Boomsma (Amsterdam, The Netherlands)

16.30-16.50 Discussion of the previous topics

MODULE 6. LUNG, THE TREE OF LIFE Chairperson: Giuseppe Buonocore (Siena, Italy)

17.30-18.00 The mysteries of bronchopulmonary dysplasia Ola D. Saugstad (Oslo, Norway)

18.00-18.30 Early origin and prevention of chronic obstructive pulmonary diseases Eugenio Baraldi (Padua, Italy)

18.30-19.00 New prospective in probiotics research Francesco Savino (Turin, Italy)

19.00-19.20 Discussion of the previous topics

SUNDAY 10 MARCH 2019

MODULE 7. SHADOWS AND LIGHTS Chairperson: Gian Luigi Marseglia (Pavia, Italy)

08.00-08.30 Impact of economic crisis on perinatal parameters and its possible deleterious DOHaD consequences Ariadne Malamitsi-Puchner (Athens, Greece)

08.30-09.00 Environment, climate and maternal-fetal effects Gian Carlo Di Renzo (Perugia, Italy)

09.00-09.30 Cesarean section: early and long-term implications Apostolos Papageorgiou (Montreal, Canada)

09-30-10-00 Multipotent stem cells of maternal milk Gavino Faa (Cagliari, Italy)

10.00-10.20 Discussion of the previous topics

SUNDAY 10 MARCH 2019 MODULE 8. THE FUTURE OF THE FUTURE Chairperson: Diego Peroni (Pisa, Italy)

10.40-11.10 Inventions and Innovations in Perinatal Medicine The Life Cycle from the Womb to the Adult Federico Mecacci (Florence, Italy), Moshe Hod (Tel Aviv, Israel),

11.10-11.40 Medical and ethical issues at the limits of viability Apostolos Papageorgiou (Montreal, Canada)

11.40-12.10 Epigenetics and the brain Gavino Faa (Cagliari, Italy)

12.10-12.40 The bridge between paediatrics and geriatrics Alberto Pilotto (Genoa, Italy

12.40-13.10 Publish or perish in pediatrics Giuseppe Buonocore (Siena, Italy)

13.10-13.30 Discussion of the previous topics

Conclusions of the course

13.30.14.00 Precision pediatrics: from protocols to personalized medicine Vassilios Fanos (Cagliari, Italy)

SPEAKERS AND CHAIRS Galileo Advanced Course on Pediatrics

Chiara Azzari(Florence, Italy)

Eugenio Baraldi(Padua, Italy)

Enrico Bertino(Turin, Italy)

Dorret Boomsma(Amsterdam, The Netherlands)

Giuseppe Buonocore(Siena, Italy)

Paolo Curatolo(Rome, Italy)

Carlo Dani(Florence, Italy)

Gian Carlo Di Renzo(Perugia, Italy)

Gian Paolo Donzelli(Florence, Italy)

Gavino Faa(Cagliari, Italy)

Vassilios Fanos(Cagliari, Italy)

Ruggiero Francavilla(Bari, Italy)

Johan Garssen(Utrecht, The Netherlands)

SPEAKERS AND CHAIRS Galileo Advanced Course on Pediatrics

Moshe Hod(Tel Aviv, Israel)

Ariadne Malamitsi-Puchner(Athens, Greece)

Gian Luigi Marseglia(Pavia, Italy)

Federico Mecacci(Florence, Italy)

Corrado Moretti(Rome, Italy)

Fabio Mosca(Milan, Italy)

Michele Mussap(Genoa, Italy)

Antonio Noto (Cagliari, Italy)

Apostolos Papageorgiou(Montreal, Canada)

Diego Peroni(Pisa, Italy)

Alberto Pilotto(Genoa, Italy)

Ola D. Saugstad(Oslo, Norway)

Francesco Savino(Turin, Italy)

Murat Yurdakok(Ankara, Turkey)

Kadriye Yurdakok(Ankara-Turkey)

INFORMATIONcongress venueSpazioEventiCastiglione,ViaColleRamolen°20,Bottailocality,50023Impruneta(FI)

dates 8/10March2019

registration fee by 27/02/2019*Surgeon €600,00+VAT22%

*Afterthisdateispossibletoregistrationonsite

the registration includes:•partecipationincongressactivities•congresskit•certificatetoattendance•C.M.E.certificate•coffeebreak•lunch

E.C.M. creditsThis event gives right to: Nr. 19 E.C.M. credits to Surgeon Ref. (555-247234) Educational Aims:ApplicationintheDailyPracticeofPrinciplesandProceduresoftheEvidenceBasedPractice(EBM- EBN - EBP). Discipline: Hematology, Gastro-enterology,Medical Genetics, Geriatrics, Respiratorydiseases,Contagiousdiseases,ClinicalandToxicologyPharmacology,MedicalGeneticLaboratory,Microbiology and Virology, Hygiene, Epidemiology and Public Health, Occupational Medicineand workplace safety, General Medicine (family doctor), Epidemiology. Surgeon’s Disciplines:AllergologyAndClinical Immunology;DermatologyAndVenereology;Gastroenterology;DiseasesOfRespiratoryApparatusInfectiousDiseases;InternalMedicine;Neonatology;Pediatrics;Psychiatry;GeneralSurgery;PediatricSurgery;Ophthalmology;OrthopedicsAndTraumatologyAnesthesiaAndRenimation;FoodHygieneofNutrition;GeneralMedicine(FamilyDoctors);Pediatrics(PediatricsOfFreeChoice);ScienceOfFoodAndDietetics;Psychotherapy;Otolaryngology.

Questionnaire On Site:ForTheCmeCreditsOfTheEventIsMandatory:ParticipationAt90%OfTheActivities(SignOnTheSignatureSheets),AnsweringCorrectlyAtLeast75%OfTheQuestionsAndFillTheEvaluationAndCustomerSatisfactionQuestionnaire.

INFORMATION

obtaining training creditsToobtaintrainingcredits,participantsneedtoparticipateinthecongressscientificactivitiesplanned foreveryday;once thecongress isover, theywillhand in theirpersonaldata,togetherwiththescientificself-evaluationandapprovalquestionnaires,fullyfilledout.

participation certificate and E.C.M. certificateAttheendofthecongress,allregularlyregisteredparticipantswillbeissuedacertificateofparticipation,whiletheE.C.M.certificatewillbeavailableon-line90daysaftertheendoftheevent(subjecttoattributionbytheministryofhealth).participantswillbeabletodownloadtheiritaliancertificateswiththecreditsobtained,byconnectingtothewebsitewww.ideacpa.comand following the simpleprocedures. europeancertificateswillbesentbyemailtotheaddresswrittenontheapprovalquestionnaireafter90daysoftheendofthecongress.

ENROLLMENT AND PAYMENT METHODSBanktransfertoBNLBNPGROUPPARIBASIBAN:IT42N0100503216000000023553SWIFTBIC:BNLIITRRpayabletoiDeacongressS.r.l.(specifythereasonforpayment).PayPalcreditcard.Toregister,logontowww.ideacpa.comandfollowtheinstructions.

CANCELLATION FOR REGISTRATIONIntheeventofcancellation,arefundisprovidedfor:-50%oftheentireamountforcancellationsreceivedby21/01/2019-Norefundforcancellationsreceivedafterthisdate.Thelackofthebalancewillnotgivetherighttoanyregistration

ABOUT FLORENCE

CURRENCY:ItalyisapartoftheEuropeanCurrencyUnitandtheofficialcurrencyintheEuro.BanksinItalyareusuallyopenMondaytoFriday9:00AM–15:30PM

CLIMATETheclimateinFlorenceisgenerallymildandcontinental.TheaveragetemperatureinFlorenceinMayrangesfrom10°Cto15°C

LANGUAGEItalianistheprimarylanguage.ThemostcommonforeignlanguageisEnglish

TIMEItalyisGMT+1Florence12:00AM-London11:00AMNewYork6:00AM-Sydney22:00PM

EMERGENCY NUMBERSCarabinieri(police)Tel.112StatepoliceTel.113FirebrigadeTel.115AmbulanceTel.118MunicipalpoliceTel.+390553285(lineopen24hoursaday-onlyforabsoluteemergencies:seriousaccidents,immediatedangerorseriousrisktopublichealth)MunicipalpoliceTel.+390553283333

ABOUT FLORENCE(lineopen24hoursaday–anyrequestforassistanceortorequestthepresenceofthemunicipalpolice)

Anti-venomCentreTel.+390557947819MedicationandpregnancyTel.+390557946731SexualviolenceandabuseTel.+390557947493MobilecoronaryunitTel.+39055214444

HEALTHCAREThefollowinghospitalsareequippedwithanemergencydepartment(ER)

AZIENDAOSPEDALIERA-UNIVERSITARIACAREGGIViadelleOblate,1-50141FlorenceTel.+39055794111

AZIENDAOSPEDALIERA-UNIVERSITARIAMEYERVialePieraccini,24-50139FlorenceTel.+3905556621

OSPEDALESANTAMARIANUOVAPiazzadiSantaMariaNuova,1-50122FlorenceTel.+3905527581

NUOVOOSPEDALESANGIOVANNIDIDIOViadiTorregalli,3-50143FlorenceTel.+3905571921

ABOUT FLORENCE

OSPEDALESANTAMARIAANNUNZIATA(PONTEANICCHERI)Viadell’Antella,58-50012BagnoaRipoli(FI)Tel.+3905524961

PRESIDIOPIEROPALAGIVialeMichelangelo,41-50125FlorenceTel.+3905565771

ELECTRICITYThevoltageinFlorenceforprivatehomes(andthusforhotels)is220/240Volts.ThepowersocketsthatareusedareoftypeF/L.

TELECOMMUNICATIONSTheareacodeforitalyfromabroadis:+39

TRANSPORTATIONBYBUSThepublictransportationnetwork(ATAF&Li-neas.c.a.r.l.)connectsthecitycentretothesuburbanareawithover100urbanandextra-urbanlines.Actually,thebusservicealsoextendstotheareasofBagnoaRipoli,Calenzano,CampiBisenzio,Fiesole,Impruneta(forTavarnuzze),Scandicci,SestoFiorentino,Vaglia(forPratolino).ThetramwayLine1isalsoactive,connectingthecentralrailwaystationofSantaMariaNovellatoScandicci.ProntoAtaTel.800424500(freecallonlyfromItaly).www.ataf.net

ABOUT FLORENCE

BYTAXITaxiscanbecalledbyphoneorcanbecaughtdirectlyfromtheappropriatereservedtaxipoints,locatedinvariouspartsofthecitycentreandinothersuburbanareas.Information:

RADIOTAXICO.TA.FI.:Tel.+390554390-+390554499RADIOTAXISO.CO.TA.:Tel.+390554242-+390554798

BYBIKEWITHTHE“MILLEEUNABICI”PROJECTWithintheprojectof“Firenzecittàciclabile”(“Florenceasacyclablecity”),theFlorenceMunicipalitygivesthecitizensandthetouriststheopportunitytorentabike,anidealwaytomoveinthecity.Information:www.comune.fi.it/servizi_pubblici/trasporti/noleggiobici.htm

PRESIDENTVassilios FanosCagliari, Italy

INTERNATIONALSCIENTIFIC BOARD

Dorret I. BoomsmaAmsterdam, The Netherlands

Giuseppe BuonocoreSiena, Italy

Carlo DaniFlorence, Italy

Ariadne Malamitsi-PuchnerAthens, Greece

Apostolos PapageorgiouMontreal, Canada

Diego PeroniPisa, Italy

Ola D. SaugstadOslo, Norway

Congress Organizer and Provider E.C.M. id. n. 555 iDea congress PiazzaGiovanniRandaccio,1•00195Roma Phone0636381573•fax0636307682 e-mail:info@ideacpa.com•www.ideacpa.com