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1 Registration Assessment 2013 Practice Questions: February Answers and Guidance Question Answer Guidance 1 Open Book B Using the Cardiovascular Risk Prediction Charts towards the back of the BNF and the clinical parameters provided, Mrs C has a cardiovascular disease risk of 10-20% over the next 10 years. 2 Open Book E BNF Section 2.5 Hypertension and heart failure. Mrs C has stage 2 hypertension and is over 55 years of age. 3 Open Book B The recommended safe limit of alcohol for a female is not more than 2 to 3 units per day, maximum of 14 units per week. Mrs C should be advised to avoid binge drinking and to have at least two alcohol free days each week. For more information see http://www.patient.co.uk/health/Recommended-Safe- Limits-of-Alcohol.htm 4 Open Book C BNF for Children 2012-2013 section 5.1 and section 5.1.2. Treatment options are benzlpenicillin and gentamicin, cefotaxine or ceftriaxone. However ceftriaxone is contra-indicated in neonates < 41 weeks postmenstrual age. 5 Open Book D BNF for Children 2012-2013 section 5.1. There are no signs of septicaemia or a complicated pneumonia and he eating a proportion of his meals therefore parenteral therapy not required at this time. A child of this age with symptoms persisting should receive treatment. There is no reason to suspect staphylococcal infections so treatment with amoxicillin alone would be appropriate. 6 Closed Book A 1. Each reconstituted vial contains 4 mg/mL = 400 mg in 100 mL = 0.4 g/100mL = 0.4% w/v 2. 2.5 mg/kg x 50 kg = 125 mg dose. Concentration 4 mg/mL therefore volume = 31.25 mL. Final concentration is 2 mg/mL therefore require addition of 31.25 mL glucose 10% 3. Total volume to be infused is 62.5 mL over 30 minutes = 125 mL per hour 7 Closed Book A 1. For non malignant indications, methotrexate is a weekly dose see BNF section 10.1.3 2. This patient has been prescribed two steroid inhalers 3. The maximum daily oral dose for an adult is 150mg (up to 200 mg in migraine) 8 Closed Book A Oxycodone hydrochloride injection is a schedule 2 controlled drug. See http://www.npc.nhs.uk/guidance_cd.php and/or Medicines, Ethics and Practice The professional guide for pharmacists Edition 36 July 2012 9 Closed Book A See BNF sections 2.8.1 and 2.8.2 10 Closed Book B See BNF section 2.8.2

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Registration Assessment 2013 Practice Questions: February Answers and Guidance

Question Answer Guidance

1 Open Book

B Using the Cardiovascular Risk Prediction Charts towards the back of the BNF and the clinical parameters provided, Mrs C has a cardiovascular disease risk of 10-20% over the next 10 years.

2 Open Book

E BNF Section 2.5 Hypertension and heart failure. Mrs C has stage 2 hypertension and is over 55 years of age.

3 Open Book

B The recommended safe limit of alcohol for a female is not more than 2 to 3 units per day, maximum of 14 units per week. Mrs C should be advised to avoid binge drinking and to have at least two alcohol free days each week. For more information see http://www.patient.co.uk/health/Recommended-Safe-Limits-of-Alcohol.htm

4 Open Book

C BNF for Children 2012-2013 section 5.1 and section 5.1.2. Treatment options are benzlpenicillin and gentamicin, cefotaxine or ceftriaxone. However ceftriaxone is contra-indicated in neonates < 41 weeks postmenstrual age.

5 Open Book

D BNF for Children 2012-2013 section 5.1. There are no signs of septicaemia or a complicated pneumonia and he eating a proportion of his meals therefore parenteral therapy not required at this time. A child of this age with symptoms persisting should receive treatment. There is no reason to suspect staphylococcal infections so treatment with amoxicillin alone would be appropriate.

6 Closed Book

A 1. Each reconstituted vial contains 4 mg/mL = 400 mg in 100 mL = 0.4 g/100mL = 0.4% w/v

2. 2.5 mg/kg x 50 kg = 125 mg dose. Concentration 4 mg/mL therefore volume = 31.25 mL. Final concentration is 2 mg/mL therefore require addition of 31.25 mL glucose 10%

3. Total volume to be infused is 62.5 mL over 30 minutes = 125 mL per hour

7 Closed Book

A 1. For non malignant indications, methotrexate is a weekly dose see BNF section 10.1.3

2. This patient has been prescribed two steroid inhalers 3. The maximum daily oral dose for an adult is 150mg (up to 200 mg in

migraine)

8 Closed Book

A Oxycodone hydrochloride injection is a schedule 2 controlled drug. See http://www.npc.nhs.uk/guidance_cd.php and/or Medicines, Ethics and Practice The professional guide for pharmacists Edition 36 July 2012

9 Closed Book

A See BNF sections 2.8.1 and 2.8.2

10 Closed Book

B See BNF section 2.8.2