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PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

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Page 1: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

1

Page 2: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

2

Page 3: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

3

Active Ingredient:

• Travoprost 40ug/ml = 0.004%

Preservative:

• 0.015% Benzalkonuim Chloride

5 ml, enough for 1 month

One drop once daily in the evening

No need for refrigeration

90.50 LE

Page 4: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Only Travonorm, the PG analogue that produces full activation for FP receptors.

Ref.: Travoprost a new prostaglandin analogue for the treatment of glaucoma. Expert OpinPharmacother. 2002

Travonorm offers 30% reduction in IOP at week 2 & week 12

Sustained IOP reduction throughout the 24-hour dosing interval

Ref.: Sustained IOP reduction throughout the day with travoprost0.004%. Clin Ophthalmol. 2012

Page 5: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Achieves from 30 to 35%

reduction in IOPPowerful IOP reduction

Decrease the progression

of visual field defects

Minimizes the diurnal

variation of the IOP

Flattens the curve when

peaks occur for maximum

protection

Decreases the risk for the

visual field deterioration

The only FP full agonist Potent IOP reductionProvides the best choice in

the Prostaglandins analogues

Has no systemic side

effects

No fear of cardiopulmonary B-blockers

side effect

5 ml Enough for one month

No need for refrigeration Once daily

Page 6: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

6

First-Line monotherapy

Travonorm is a Golden Therapy in glaucoma management to be

indicated as a 1st line monotherapy

“The only FP full agonist”

Page 7: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Active Ingredient

Latanoprost 50ug/ml = 0.005%

Preservative

0.02% Benzalkonuim Chloride

3ml solution

One daily

60 LE

Page 8: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

8

Achieves from 30 to 35%

reduction in IOPPowerful IOP reduction

Decrease the progression

of visual field defects

Minimizes the diurnal

variation of the IOP

Flattens the curve when

peaks occur for maximum

protection

Decreases the risk for the

visual field deterioration

Has no systemic side effectsNo fear of cardiopulmonary

B-blockers side effect

Indicated as 1st line

therapy

Once daily

Page 9: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Active Ingredients:

• Dorzolamide Hydrochloride equivalent to Dorzolamide 20mg/ml = 2%

• Timolol Maleate equivalent to Timolol 5mg/ml = 0.5%

Preservative:

• 0.0075% Benzalkonuim Chloride

5ml solution

Two times daily.

50 LE

Achieves from 30 to 35%

reduction in IOPPotent IOP reduction

Decrease the progression

of visual field defects

Inhibits inflow of A.H.

by two different actions

Rapid reduction in IOP

(up to 50% in one month)

Protects optic disc from

damage & decreases the

risk of vision loss

Improves ocular

circulation

Protects the optic nerve

fibers by increasing the

blood supply

Prevents further optic disc

cupping and hence decreases

the visual field loss

HPMC formula No burning

or stinging or dry eyeExcellent local tolerability

Page 10: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Active Ingredient:

• Brimonidine tartrate 1.5 mg/ml = 0.15%

Preservative:

• Sodium Chlorite “Purite”

• The preservative free in the eye:

Oxychloro-complex Light NaCl + H2O + O2

(Purite) Human Tear component

5 ml solution

Three times daily

Price : 31 LE

Page 11: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Reaches the vitreous in a

physiological concentration

Act directly on retinal

Alpha 2 receptorsNeuro-protective Effect

Enhances RGCs

survivalNeuro-protective Effect

Decreases the risk for the

visual field deterioration

Neuro-protective effect Ideal adjuvant therapy Visual field stabilization

Preservative: PuriteLess incidence of ocular

allergyPatient’s compliance

High systemic safetySafe for cardiac &

asthmatic patients

Page 12: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Active Ingredient:

• Brimonidine 0.2% / Timolol 0.5%

Preservative:

• 0.0075% Benzalkonuim Chloride

5 ml solution

Two times daily

Price : 39 LE

Page 13: PowerPoint Presentation€¦ · Potent IOP reduction Decrease the progression of visual field defects Inhibits inflow of A.H. by two different actions Rapid reduction in IOP (up to

29/01/2018

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Neuro-protection added

value

Prevents further

cupping

Decreases the progression

of visual field defects

Powerful reduction in

IOP

Reliable anti-glaucoma

medication

Less burning & stinging

than DTFCHigh ocular tolerability