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Poster 71 Introduction to High Resolution Scanning of the Anterior Segment Using the New Visante OCT Jerome Sherman, O.D., Jeffrey Roth, O.D., and Rick Torney, State University of New York, State College of Optometry, 33 West 42 nd Street, New York, New York 10036 Background: Although high-resolution sections of the pos- terior pole (including the retina and optic nerve head) have been available for several years with the Stratus OCT III, comparable high-resolution scans of the anterior segment have been limited to ultrasound technology using the UBM (ultrasound bio-microscope). Methods: A retrospective review of available images is provided, including various corneal diseases, post-corneal surgery, anterior filtration angle assessment, iris abnormal- ities, and anterior segment cysts and solid lesions. Results: As in the posterior segment, OCT yields high- resolution images of the anterior segment that are generally superior to ultrasound. One major advantage of ultrasound (B-scan and UBM) is its ability to penetrate tissue. Just as B-scan is better than OCT Stratus for detection of choroidal lesions, the UBM is better than the Visante in ciliary body tumors. Conclusions: The Visante OCT produces remarkable high- resolution images of the anterior segment that may be helpful in the diagnosis and management of myriad disor- ders. The Visante OCT joins the UBM in its ability to image the anterior segment and is generally better than UBM, except in cases of cililary body mass lesions. (Dr. Sherman lectures for Zeiss Meditec.) Poster 72 Ocular Complications Associated with Molluscum Contagiosum Zoeanne Schinas, O.D., and Julie Tyler, O.D., Nova Southeastern University, College of Optometry, 3200 South University Drive, Ft. Lauderdale, Florida 33328 Background: Molluscum contagiosum is a highly conta- gious dermatologic condition associated with ocular com- plications when occurring on the lid margin. Most com- monly seen in childhood, it has been associated with HIV infection in adults. If a lesion is not removed in a timely fashion, significant ocular surface complications may de- velop. Case Report: A 23-year-old man came to us for an eye examination reporting redness and mildly decreased vi- sion O.S. for 3 months’ duration. He reported having been diagnosed and treated for Chlamydia 6 months earlier, at which time he also tested negatively for syph- ilis, gonorrhea, and HIV. Entering DVA was 20/20 O.D. and 20/50 O.S. Preliminary testing was unremarkable. Biomicroscopy revealed a moderate follicular response with significant conjunctival injection, and corneal infil- tration at the limbus 360 degrees O.S. Noted on the superior lid was a 1-mm round, flesh-colored, elevated lesion with an umbilicated center. On being questioned, the patient acknowledged an awareness of the lesion, with a recent change in size. Additional test results, including funduscopy, were normal OU. Methods: A diagnosis of Mulloscum contagiosum of the lid with secondary viral keratoconjunctivitis O.S. was made and an oculoplastic consult was obtained for surgical exci- sion. Prophylactic treatment for the corneal findings was initiated O.S. using Vigamox q6h. Two days later, the patient’s vision improved to 20/30 O.S., though the appear- ance of the anterior segment remained unchanged. Lotemax q6h and artificial tears q.i.d. O.S. were added to the treat- ment regimen. Results: A followup visit was scheduled in 1 week for continued monitoring of signs and symptoms O.S. The patient was educated on the importance of repeating HIV testing in 6 months. Conclusion: This case illustrates noteworthy corneal complications that may occur in a presumed HIV-nega- tive adult with molluscum contagiosum. Practitioners should note the importance of differentially diagnosing this viral condition. Poster 73 Evaluation of Efficacy of a New Liquid Gel Concept Artificial Tear Mike Christensen, O.D., Ph.D., Marion Tudor, M.P.H., David Meadows, Ph.D., and Ralph Stone, Ph.D., Alcon Laboratories, Ltd., 6201 South Freeway, Fort Worth, Texas 76134 Purpose: The purpose of this poster is to evaluate efficacy of a new Concept Tear. Methods: The Concept Tear (Alcon Labs, Inc.) is a multi- dose formulation, with buffer ingredients that work in con- cert to provide preservative efficacy without traditional preservatives. Like Systane® Lubricant Eye Drops, it con- tains PEG– 400 and PG as active demulcents ,with HP–Guar as a gelling agent. Unlike Systane, it is a structured gel in the bottle. Two clinical studies are summarized herein. Study 1—One hundred thirty-five dry eye patients (45 per arm) were enrolled in a randomized, double-masked, paral- lel study of 6 weeks’ duration. Eligible patients demon- strated a sum 3 NEI corneal staining score and needed artificial tears at least “some of the time.” Controls were Unit dose with 0.5% CMC and Multi-dose with 0.5% CMC (PURITE–Allergan). Signs/symptoms were monitored weekly. Study 2—Acute comfort and blur comparison were made between the new Concept Tear and a CMC 1% tear with PURITE (Allergan, Inc.). This was a double-masked, randomized, 2-period cross-over study of one dose duration. Drops were administered OU per randomization. Drop in- stillation comfort, acceptability, and 3-minute blur profile comparisons were made. 294 Optometry, Vol 77, No 6, June 2006

Poster 71: Introduction to High Resolution Scanning of the Anterior Segment Using the New Visante OCT

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Poster 71

Introduction to High Resolution Scanning of theAnterior Segment Using the New Visante OCTJerome Sherman, O.D., Jeffrey Roth, O.D., andRick Torney, State University of New York, State Collegeof Optometry, 33 West 42nd Street, New York, New York10036

Background: Although high-resolution sections of the pos-terior pole (including the retina and optic nerve head) havebeen available for several years with the Stratus OCT III,comparable high-resolution scans of the anterior segmenthave been limited to ultrasound technology using the UBM(ultrasound bio-microscope).Methods: A retrospective review of available images isprovided, including various corneal diseases, post-cornealsurgery, anterior filtration angle assessment, iris abnormal-ities, and anterior segment cysts and solid lesions.Results: As in the posterior segment, OCT yields high-resolution images of the anterior segment that are generallysuperior to ultrasound. One major advantage of ultrasound(B-scan and UBM) is its ability to penetrate tissue. Just asB-scan is better than OCT Stratus for detection of choroidallesions, the UBM is better than the Visante in ciliary bodytumors.Conclusions: The Visante OCT produces remarkable high-resolution images of the anterior segment that may behelpful in the diagnosis and management of myriad disor-ders. The Visante OCT joins the UBM in its ability to imagethe anterior segment and is generally better than UBM,except in cases of cililary body mass lesions. (Dr. Shermanlectures for Zeiss Meditec.)

Poster 72

Ocular Complications Associated with MolluscumContagiosumZoeanne Schinas, O.D., and Julie Tyler, O.D., NovaSoutheastern University, College of Optometry, 3200South University Drive, Ft. Lauderdale, Florida 33328

Background: Molluscum contagiosum is a highly conta-gious dermatologic condition associated with ocular com-plications when occurring on the lid margin. Most com-monly seen in childhood, it has been associated with HIVinfection in adults. If a lesion is not removed in a timelyfashion, significant ocular surface complications may de-velop.Case Report: A 23-year-old man came to us for an eyeexamination reporting redness and mildly decreased vi-sion O.S. for 3 months’ duration. He reported havingbeen diagnosed and treated for Chlamydia 6 monthsearlier, at which time he also tested negatively for syph-ilis, gonorrhea, and HIV. Entering DVA was 20/20 O.D.and 20/50 O.S. Preliminary testing was unremarkable.Biomicroscopy revealed a moderate follicular responsewith significant conjunctival injection, and corneal infil-

tration at the limbus 360 degrees O.S. Noted on thesuperior lid was a 1-mm round, flesh-colored, elevatedlesion with an umbilicated center. On being questioned,the patient acknowledged an awareness of the lesion,with a recent change in size. Additional test results,including funduscopy, were normal OU.Methods: A diagnosis of Mulloscum contagiosum of the lidwith secondary viral keratoconjunctivitis O.S. was madeand an oculoplastic consult was obtained for surgical exci-sion. Prophylactic treatment for the corneal findings wasinitiated O.S. using Vigamox q6h. Two days later, thepatient’s vision improved to 20/30 O.S., though the appear-ance of the anterior segment remained unchanged. Lotemaxq6h and artificial tears q.i.d. O.S. were added to the treat-ment regimen.Results: A followup visit was scheduled in 1 week forcontinued monitoring of signs and symptoms O.S. Thepatient was educated on the importance of repeating HIVtesting in 6 months.Conclusion: This case illustrates noteworthy cornealcomplications that may occur in a presumed HIV-nega-tive adult with molluscum contagiosum. Practitionersshould note the importance of differentially diagnosingthis viral condition.

Poster 73

Evaluation of Efficacy of a New Liquid Gel ConceptArtificial TearMike Christensen, O.D., Ph.D., Marion Tudor, M.P.H.,David Meadows, Ph.D., and Ralph Stone, Ph.D., AlconLaboratories, Ltd., 6201 South Freeway, Fort Worth,Texas 76134

Purpose: The purpose of this poster is to evaluate efficacyof a new Concept Tear.Methods: The Concept Tear (Alcon Labs, Inc.) is a multi-dose formulation, with buffer ingredients that work in con-cert to provide preservative efficacy without traditionalpreservatives. Like Systane® Lubricant Eye Drops, it con-tains PEG–400 and PG as active demulcents ,with HP–Guaras a gelling agent. Unlike Systane, it is a structured gel inthe bottle. Two clinical studies are summarized herein.Study 1—One hundred thirty-five dry eye patients (45 perarm) were enrolled in a randomized, double-masked, paral-lel study of 6 weeks’ duration. Eligible patients demon-strated a sum � � 3 NEI corneal staining score and neededartificial tears at least “some of the time.” Controls wereUnit dose with 0.5% CMC and Multi-dose with 0.5% CMC(PURITE–Allergan). Signs/symptoms were monitoredweekly. Study 2—Acute comfort and blur comparison weremade between the new Concept Tear and a CMC 1% tearwith PURITE (Allergan, Inc.). This was a double-masked,randomized, 2-period cross-over study of one dose duration.Drops were administered OU per randomization. Drop in-stillation comfort, acceptability, and 3-minute blur profilecomparisons were made.

294 Optometry, Vol 77, No 6, June 2006