Plateletworks POC Platelet Function

Plateletworks POC Platelet FunctionResults in 2 minutes with a standard cell counter!• Platelet Count • Platelet Inhibition• Platelet Aggregation • CBC • Efficient pre-surgical screen • Monitor anti-platelet therapies • Determine best use of transfusion resources • Uses traditional ADP and collagen agonists • No specialized training or equipment • Use whole blood at the point of care

Cascade® POC SystemPoint of Care for Whole Blood CoagulationThe Cascade POC analyzer and unique reagent system are useful in monitoring routine anticoagulants and the antithrombotic drugs used to treat angina, MI, stroke, deep venous thrombosis and pulmonary and arterial emboli. A built-in battery pack and QC lockout features make it ideal for use in the ER, cath lab, cardiac surgery, warfarin clinics and physician offices. Cascade POC offers a rapid POC assay for monitoring the anticoagulant effects of warfarin.

Testing is fast and easy:1. Swipe test card through reader.2. Insert card into analyzer and add sample.3. View final results in minutes

Cascade POC Assays• PT with INR (ISI ~ 1.0)

– PT-WB for fresh whole blood

– PT-C for citrated whole blood or plasma

• aPTT for citrated whole blood or plasma

• c-ACT for fresh whole blood

Actalyke POC Heparin AssessmentActivated Clotting Time

• 2-point early clot detection• Single and dual well models• Extensive data handling• Celite, Kaolin, Glass or MAX-ACT tests

Book M8/11(4)

800-231-5663•www.helena.com

Helena HemostasisHelena Hemostasis

Page 1 Page 6

Helena Thromboplastins offer a range of ISI values to provide a reagent that’s just right for your lab. Reagents are prepared from rabbit brain tissue and are suitable for automated, semi-automated and manual applications.

5248 Thromboplastin-LI, 250 tests, 10 x 5 mL 5249 Thromboplastin-LI, 500 tests, 10 x 10 mL 5274 Thromboplastin-MI with Diluent, 125 tests, 5 x 5 mL 5271 Thromboplastin-MI with Diluent, 250 tests, 5 x 10 mL 5272 Thromboplastin-MI with Diluent, 500 tests, 10 x 10 mL 5380 Thromboplastin, 200 tests, 10 x 4 mL 5381 Thromboplastin, 500 tests, 10 x 10 mL

Thromboplastin-LI• Ready for use; no mixing required• Stability of open reagent: 14 days at 2-8°C• Target ISI value: < 1.5

Thromboplastin-MI• Convenient add-a-vial diluent included in kit to eliminate pipetting errors and water problems • Reconstituted stability: 7 days at 2-6°C• Target ISI value: 1.6 to 1.8

Thromboplastin• Reconstituted stability: 7 days at 2-6°C• Target ISI value: 2.0 to 2.5

Prothrombin TimePlatelet aggregation is performed to identify abnormal platelet function, to quantitate platelet response, and to monitor platelet inhibition by drug therapy. Helena’s platelet reagents provide outstanding stability and reasonable pricing. Reagents are optimized for use with Helena’s AggRAM, but may be used on any turbidometric aggregometer of similar quality.

ADP• Lyophilized preparation of adenosine-5-diphosphate• Reconstitutes to a 20 µM stock solution• Stability of stock solution: 1 week at 2-8°C or 3 months at -20°C

Collagen• One of the world’s best collagen preparations• Clear stabilized liquid prepared from equine tendon• 10 µg/mL concentration

Epinephrine• Lyophilized preparation of L-epinephrine bitartrate• Reconstitutes to 300 µM • Stability of stock solution: 1 week at 2-8°C

5364 Arachidonic Acid, 2 x 1 mL 5366 ADP, 2 x 1 mL 5367 Epinephrine, 2 x 1 mL5368 Collagen, 2 x 1 mL5369 Platelet Aggregation Kit (5366, 5367, 5368) 5199 Ristocetin (for RIPA), 10 x 0.5 mL5365 Tris-Buffered Saline, 1 x 125 mL

The Ristocetin Cofactor assay measures the ability of vWF in the patient’s plasma to agglutinate formalin-fixed (metabolically inactive) platelets in the presence of ristocetin. This assay is more sensitive than RIPA to mild reductions in vWF and more often used to monitor therapy in vWD patients.

Arachidonic Acid• Lyophilized preparation of sodium arachidonate• Useful in evaluating aspirin-induced platelet

dysfunction• It has been suggested that this test be performed

before other testing to screen for drugs effecting platelet responsiveness

Ristocetin• Derived from the actinomycete Nocardia lurida • For use in ristocetin-induced platelet aggregation (RIPA)

assays• Concentration post-reconstitution is 15 mg/mL• Reconstituted stability: 4 hours at 15-30°C or 1 month at -20°C

Platelet Aggregation Studies

Ristocetin Cofactor Assay

5370 Ristocetin Cofactor Kit, 60 tests 5356 Lyophilized Platelets, 5 x 10 mL 5371 Lyophilized Platelets, 5 x 5 mL5373 Ristocetin Cofactor Abnormal Control, 5 x 0.5 mL5372 Ristocetin (10 mg/mL), 5 x 1.5 mL 5365 Tris-Buffered Saline, 1 x 125 mL

Ristocetin Cofactor Assay• Kit includes ristocetin (10 mg/mL; 2 x 1.5 mL), formalinized platelets (~200,000/mL; 4 x 5 mL), S.A.R.P. reference plasma (2 x 1 mL), abnormal control (R:Co <50%; 2 x 0.5 mL), and tris-buffered saline (1 x 35 mL)• Items also available separately• Platelets in Cat. No. 5356 show a slower reaction rate

than platelets in Cat. No. 5371

Helena aPTT reagents are ready-to-use liquids for convenience, high quality for precision, and priced for economy. Reagents are suitable for photo-optical, mechanical and manual (tilt tube) methods.

5388 aPTT-SA & CaCl2, 250 tests, 5 x 5 mL5389 aPTT-SA & CaCl2, 500 tests, 5 x 10 mL5387 aPTT-SA, 1000 tests, 10 x 10 mL 5386 0.025 M CaCl2, 10 x 10 mL

Activated Partial Thromboplastin Time

aPTT-SA (Soluble Activator)• Soluble ellagic acid activator• Optical clarity, homogeneous suspension a plus for automated systems• Shorter activation time (~3 minutes vs. 5 minutes)


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Thrombin Clotting Time• Excellent, rapid screening test for qualitative

assessment of plasma fibrinogen and interfering substances such as heparin and FDP

• Uses a low concentration of heparin (~3 NIH units/mL) with undiluted plasma

• Sensitive to fibrinogen levels below 70 mg/dL

• Easy-to-use keyboard• On-screen prompts• State-of-the-art optics• On-board quality control

Thrombin Clotting TimeThe Thrombin Clotting Time, or Thrombin Time (TT), assay is ideal for qualitative assessment of plasma fibrinogen and interfering substances such as FDP and heparin.

5377 Thrombin Time Reagent, 250 tests, 10 x 5 mL

Cat. No. 1711 Cat. No. 1710

von Willebrand Factor Antigen (vWF:Ag)• Total incubation time 40 minutes at room temperature; overall

assay time 55 minutes for 96 determinations• Linearity expressed as the coefficient of determination (r2)

0.995; mean accuracy 103.6%

Protein C• Simple protocol - total incubation time 60 minutes; overall

assay time 75 minutes for 96 determinations• Linearity (r2) 0.992; mean accuracy 99.4%

Protein S (Free and Total)• Simultaneous measurement of Free and Total by pretreating

with PEG• Linearity (r2) 0.985 for Total, 0.992 for Free; mean accuracy

101% for Total, 98% for Free

ELISA kits offer sensitive and specific assays with faster turnaround times, greater ease of use, and clear-cut standardized results using established reference preparations. Antigen assays employ 6-point reference curves with accurate detection as low as 5% of normal.

vWF:Ag, PC & PS ELISA Assays

AggRAM™

5290 vWF:Ag ELISA Kit, 96 determinations 5291 Protein C ELISA Kit, 96 determinations 5292 Protein S ELISA Kit, 96 determinations

Fibrinogen• Clauss methodology for quantitation of fibrinogen in

acquired and congenital disorders• Uses high thrombin (~100 NIH units/mL) and low

fibrinogen (2 to 50 mg/dL) concentrations so that clotting times are dependent on plasma fibrinogen

• Not significantly effected by heparin concentrations below 0.6 USP units/mL and FDP below 100 µg/mL

For quantitative assessment of fibrinogen, Helena’s Fibrinogen Assay is well-suited to automated, semi-automated and manual systems. Fibrinogen Assay components are available as a kit and separately.

Cascade M and Cascade M-4 are manual hemostasis analyzers that are ideal for all routine clotting assays - PTs, aPTTs, thrombins, fibrinogens and factor assays. Operation is simple and economical, with only a 15” x 15” footprint.

Fibrinogen

Cascade® M and Cascade® M-4

5376 Fibrinogen Assay Kit, 100 tests Thrombin Reagent 5 x 2 mL, Fibrinogen Calibrator 2 x 1 mL, Owren’s Veronal Buffer 2 x 25 mL

5374 Thrombin Reagent, 200 tests, 10 x 2 mL 5375 Owren’s Veronal Buffer, 10 x 25 mL 5379 Fibrinogen Calibrator, 10 x 1 mL

AggRAM, for platelet aggregation and ristocetin cofactor testing, couples a four-channel analyzer with the power of Window®-based software for unsurpassed testing flexibility. Up to two AggRAM modules can be run on one Remote Analyzer Module computer so you can configure your analyzers to suit you testing needs.

®Windows registered trademark of Microsoft Corp.

Cat. No. 1484


Page 3 Page 4

PT, aPTT and Fibrinogen Controls• Norm-Trol 1 is prepared from lyophilized normal human

plasma to provide a normal level control for PT, aPTT, and Fibrinogen assays

• Ab-Trol 2 and Ab-Trol 3 are lyophilized absorbed human plasmas which provide moderately elevated and very elevated, respectively, PT and aPTT controls

• Reconstituted controls: stable 8 hours at 2 to 6°C

Specialty Assayed Controls and Reference Plasma• S.A.R.P. is a highly acclaimed reference plasma

standardized to WHO and ISTH. It is prepared from a frozen pool of citrated plasma from healthy donors. The pool is buffered and lyophilized to ensure stability of all plasma constituents.

• Our Specialty Assayed Controls are available in two levels: S.A.C.-1 normal and S.A.C.-2 abnormal (<60% of normal)

• S.A.R.P. and S.A.C. are assayed for these parameters: PT, aPTT, Fibrinogen, Factors II, V, VII, VIII, IX, X, XI, XII, Protein C, Protein S (free & total), Ristocetin Cofactor, and vWF:Ag

Our controls and reference plasmas offer a sensible means to monitor accuracy and precision in hemostasis testing. We encourage you to enroll in our free Quality Assurance Review (QAR) service.

Hemostasis Controls and Reference Plasmas

5186 Norm-Trol 1, 10 x 1 mL5187 Ab-Trol 2, 10 x 1 mL5183 Ab-Trol 3, 10 x 1 mL5301 S.A.C.-1 (Normal), 10 x 1 mL5302 S.A.C.-2 (Abnormal), 10 x 1 mL5185 S.A.R.P., 10 x 1 mL

Quality laboratory testing is essential to diagnosis and treatment. Helena offers quality factor deficient substrates with < 1% residual factor activity. All substrates (except Factor II) are prepared from human congenitally deficient donors.

Congenital Factor Deficient Substrates5191 Factor V Deficient Substrate, 10 x 1 mL 5192 Factor VII Deficient Substrate, 10 x 1 mL 5193 Factor VIII Deficient Substrate, 10 x 1 mL 5194 Factor IX Deficient Substrate, 10 x 1 mL 5195 Factor X Deficient Substrate, 10 x 1 mL 5196 Factor XI Deficient Substrate, 10 x 1 mL 5197 Factor XII Deficient Substrate, 10 x 1 mL

Bovine Factor Deficient Substrate Plasma5190 Factor II Deficient Substrate, 10 x 1 mL

Factor Deficient Substrates

Quality Assurance Review (QAR)• We offer QAR, a free computer service for analyzing

daily QC data for shifts or trends and establishing mean control values for individual laboratories

• QAR allows you to compare your results to other labs using the same reagents, instruments and controls

• Retrospective peer reports include precision data on the various instrument-reagent systems being used

• Ask to enroll in this free service when placing your order for Norm-Trol 1, Ab-Trol 2, and Ab-Trol 3

Complete line of supplies for quantitating vWF:Ag, Protein C, and Protein S (Free and Total) by the Laurell Rocket method, a technique which combines the specificity of immunochemistry with the ease of electrophoresis.

Laurell Rocket Electroimmunodiffusion (EID)

5361 vWF:Ag Rocket Plates, 5 x 10 wells/plate 5016 Electra B1 Buffer (for vWF:Ag), 10 x 14.1 g 5357 Protein C Rocket Plates, 5 x 12 wells/plate 5359 Protein S Rocket Plates, 5 x 12 wells/plate5363 Free Protein S Reagent, 5 x 2 mL 5358 Tris-Tricine Buffer (for Proteins C & S), 10 x 14.1 g 5362 Rocket Stain, 1 x 0.9 g

von Willebrand Factor Antigen (vWF:Ag), Protein C and Protein S• Crisp, easy-to-read, well-defined precipitin rockets

• All Helena rocket assays use same equipment and technique for ease and convenience

• Components available separately for greater economy

• Easy, accurate, specific antigen measurement

• Free Protein S can be assayed on the same plate as total Protein S by treating the sample with Free Protein S reagent


Page 3 Page 4

PT, aPTT and Fibrinogen Controls• Norm-Trol 1 is prepared from lyophilized normal human

plasma to provide a normal level control for PT, aPTT, and Fibrinogen assays

• Ab-Trol 2 and Ab-Trol 3 are lyophilized absorbed human plasmas which provide moderately elevated and very elevated, respectively, PT and aPTT controls

• Reconstituted controls: stable 8 hours at 2 to 6°C

Specialty Assayed Controls and Reference Plasma• S.A.R.P. is a highly acclaimed reference plasma

standardized to WHO and ISTH. It is prepared from a frozen pool of citrated plasma from healthy donors. The pool is buffered and lyophilized to ensure stability of all plasma constituents.

• Our Specialty Assayed Controls are available in two levels: S.A.C.-1 normal and S.A.C.-2 abnormal (<60% of normal)

• S.A.R.P. and S.A.C. are assayed for these parameters: PT, aPTT, Fibrinogen, Factors II, V, VII, VIII, IX, X, XI, XII, Protein C, Protein S (free & total), Ristocetin Cofactor, and vWF:Ag

Our controls and reference plasmas offer a sensible means to monitor accuracy and precision in hemostasis testing. We encourage you to enroll in our free Quality Assurance Review (QAR) service.

Hemostasis Controls and Reference Plasmas

5186 Norm-Trol 1, 10 x 1 mL5187 Ab-Trol 2, 10 x 1 mL5183 Ab-Trol 3, 10 x 1 mL5301 S.A.C.-1 (Normal), 10 x 1 mL5302 S.A.C.-2 (Abnormal), 10 x 1 mL5185 S.A.R.P., 10 x 1 mL

Quality laboratory testing is essential to diagnosis and treatment. Helena offers quality factor deficient substrates with < 1% residual factor activity. All substrates (except Factor II) are prepared from human congenitally deficient donors.

Congenital Factor Deficient Substrates5191 Factor V Deficient Substrate, 10 x 1 mL 5192 Factor VII Deficient Substrate, 10 x 1 mL 5193 Factor VIII Deficient Substrate, 10 x 1 mL 5194 Factor IX Deficient Substrate, 10 x 1 mL 5195 Factor X Deficient Substrate, 10 x 1 mL 5196 Factor XI Deficient Substrate, 10 x 1 mL 5197 Factor XII Deficient Substrate, 10 x 1 mL

Bovine Factor Deficient Substrate Plasma5190 Factor II Deficient Substrate, 10 x 1 mL

Factor Deficient Substrates

Quality Assurance Review (QAR)• We offer QAR, a free computer service for analyzing

daily QC data for shifts or trends and establishing mean control values for individual laboratories

• QAR allows you to compare your results to other labs using the same reagents, instruments and controls

• Retrospective peer reports include precision data on the various instrument-reagent systems being used

• Ask to enroll in this free service when placing your order for Norm-Trol 1, Ab-Trol 2, and Ab-Trol 3

Complete line of supplies for quantitating vWF:Ag, Protein C, and Protein S (Free and Total) by the Laurell Rocket method, a technique which combines the specificity of immunochemistry with the ease of electrophoresis.

Laurell Rocket Electroimmunodiffusion (EID)

5361 vWF:Ag Rocket Plates, 5 x 10 wells/plate 5016 Electra B1 Buffer (for vWF:Ag), 10 x 14.1 g 5357 Protein C Rocket Plates, 5 x 12 wells/plate 5359 Protein S Rocket Plates, 5 x 12 wells/plate5363 Free Protein S Reagent, 5 x 2 mL 5358 Tris-Tricine Buffer (for Proteins C & S), 10 x 14.1 g 5362 Rocket Stain, 1 x 0.9 g

von Willebrand Factor Antigen (vWF:Ag), Protein C and Protein S• Crisp, easy-to-read, well-defined precipitin rockets

• All Helena rocket assays use same equipment and technique for ease and convenience

• Components available separately for greater economy

• Easy, accurate, specific antigen measurement

• Free Protein S can be assayed on the same plate as total Protein S by treating the sample with Free Protein S reagent


Page 5 Page 2

Thrombin Clotting Time• Excellent, rapid screening test for qualitative

assessment of plasma fibrinogen and interfering substances such as heparin and FDP

• Uses a low concentration of heparin (~3 NIH units/mL) with undiluted plasma

• Sensitive to fibrinogen levels below 70 mg/dL

• Easy-to-use keyboard• On-screen prompts• State-of-the-art optics• On-board quality control

Thrombin Clotting TimeThe Thrombin Clotting Time, or Thrombin Time (TT), assay is ideal for qualitative assessment of plasma fibrinogen and interfering substances such as FDP and heparin.

5377 Thrombin Time Reagent, 250 tests, 10 x 5 mL

Cat. No. 1711 Cat. No. 1710

von Willebrand Factor Antigen (vWF:Ag)• Total incubation time 40 minutes at room temperature; overall

assay time 55 minutes for 96 determinations• Linearity expressed as the coefficient of determination (r2)

0.995; mean accuracy 103.6%

Protein C• Simple protocol - total incubation time 60 minutes; overall

assay time 75 minutes for 96 determinations• Linearity (r2) 0.992; mean accuracy 99.4%

Protein S (Free and Total)• Simultaneous measurement of Free and Total by pretreating

with PEG• Linearity (r2) 0.985 for Total, 0.992 for Free; mean accuracy

101% for Total, 98% for Free

ELISA kits offer sensitive and specific assays with faster turnaround times, greater ease of use, and clear-cut standardized results using established reference preparations. Antigen assays employ 6-point reference curves with accurate detection as low as 5% of normal.

vWF:Ag, PC & PS ELISA Assays

AggRAM™

5290 vWF:Ag ELISA Kit, 96 determinations 5291 Protein C ELISA Kit, 96 determinations 5292 Protein S ELISA Kit, 96 determinations

Fibrinogen• Clauss methodology for quantitation of fibrinogen in

acquired and congenital disorders• Uses high thrombin (~100 NIH units/mL) and low

fibrinogen (2 to 50 mg/dL) concentrations so that clotting times are dependent on plasma fibrinogen

• Not significantly effected by heparin concentrations below 0.6 USP units/mL and FDP below 100 µg/mL

For quantitative assessment of fibrinogen, Helena’s Fibrinogen Assay is well-suited to automated, semi-automated and manual systems. Fibrinogen Assay components are available as a kit and separately.

Cascade M and Cascade M-4 are manual hemostasis analyzers that are ideal for all routine clotting assays - PTs, aPTTs, thrombins, fibrinogens and factor assays. Operation is simple and economical, with only a 15” x 15” footprint.

Fibrinogen

Cascade® M and Cascade® M-4

5376 Fibrinogen Assay Kit, 100 tests Thrombin Reagent 5 x 2 mL, Fibrinogen Calibrator 2 x 1 mL, Owren’s Veronal Buffer 2 x 25 mL

5374 Thrombin Reagent, 200 tests, 10 x 2 mL 5375 Owren’s Veronal Buffer, 10 x 25 mL 5379 Fibrinogen Calibrator, 10 x 1 mL

AggRAM, for platelet aggregation and ristocetin cofactor testing, couples a four-channel analyzer with the power of Window®-based software for unsurpassed testing flexibility. Up to two AggRAM modules can be run on one Remote Analyzer Module computer so you can configure your analyzers to suit you testing needs.

®Windows registered trademark of Microsoft Corp.

Cat. No. 1484


Page 1 Page 6

Helena Thromboplastins offer a range of ISI values to provide a reagent that’s just right for your lab. Reagents are prepared from rabbit brain tissue and are suitable for automated, semi-automated and manual applications.

5248 Thromboplastin-LI, 250 tests, 10 x 5 mL 5249 Thromboplastin-LI, 500 tests, 10 x 10 mL 5274 Thromboplastin-MI with Diluent, 125 tests, 5 x 5 mL 5271 Thromboplastin-MI with Diluent, 250 tests, 5 x 10 mL 5272 Thromboplastin-MI with Diluent, 500 tests, 10 x 10 mL 5380 Thromboplastin, 200 tests, 10 x 4 mL 5381 Thromboplastin, 500 tests, 10 x 10 mL

Thromboplastin-LI• Ready for use; no mixing required• Stability of open reagent: 14 days at 2-8°C• Target ISI value: < 1.5

Thromboplastin-MI• Convenient add-a-vial diluent included in kit to eliminate pipetting errors and water problems • Reconstituted stability: 7 days at 2-6°C• Target ISI value: 1.6 to 1.8

Thromboplastin• Reconstituted stability: 7 days at 2-6°C• Target ISI value: 2.0 to 2.5

Prothrombin TimePlatelet aggregation is performed to identify abnormal platelet function, to quantitate platelet response, and to monitor platelet inhibition by drug therapy. Helena’s platelet reagents provide outstanding stability and reasonable pricing. Reagents are optimized for use with Helena’s AggRAM, but may be used on any turbidometric aggregometer of similar quality.

ADP• Lyophilized preparation of adenosine-5-diphosphate• Reconstitutes to a 20 µM stock solution• Stability of stock solution: 1 week at 2-8°C or 3 months at -20°C

Collagen• One of the world’s best collagen preparations• Clear stabilized liquid prepared from equine tendon• 10 µg/mL concentration

Epinephrine• Lyophilized preparation of L-epinephrine bitartrate• Reconstitutes to 300 µM • Stability of stock solution: 1 week at 2-8°C

5364 Arachidonic Acid, 2 x 1 mL 5366 ADP, 2 x 1 mL 5367 Epinephrine, 2 x 1 mL5368 Collagen, 2 x 1 mL5369 Platelet Aggregation Kit (5366, 5367, 5368) 5199 Ristocetin (for RIPA), 10 x 0.5 mL5365 Tris-Buffered Saline, 1 x 125 mL

The Ristocetin Cofactor assay measures the ability of vWF in the patient’s plasma to agglutinate formalin-fixed (metabolically inactive) platelets in the presence of ristocetin. This assay is more sensitive than RIPA to mild reductions in vWF and more often used to monitor therapy in vWD patients.

Arachidonic Acid• Lyophilized preparation of sodium arachidonate• Useful in evaluating aspirin-induced platelet

dysfunction• It has been suggested that this test be performed

before other testing to screen for drugs effecting platelet responsiveness

Ristocetin• Derived from the actinomycete Nocardia lurida • For use in ristocetin-induced platelet aggregation (RIPA)

assays• Concentration post-reconstitution is 15 mg/mL• Reconstituted stability: 4 hours at 15-30°C or 1 month at -20°C

Platelet Aggregation Studies

Ristocetin Cofactor Assay

5370 Ristocetin Cofactor Kit, 60 tests 5356 Lyophilized Platelets, 5 x 10 mL 5371 Lyophilized Platelets, 5 x 5 mL5373 Ristocetin Cofactor Abnormal Control, 5 x 0.5 mL5372 Ristocetin (10 mg/mL), 5 x 1.5 mL 5365 Tris-Buffered Saline, 1 x 125 mL

Ristocetin Cofactor Assay• Kit includes ristocetin (10 mg/mL; 2 x 1.5 mL), formalinized platelets (~200,000/mL; 4 x 5 mL), S.A.R.P. reference plasma (2 x 1 mL), abnormal control (R:Co <50%; 2 x 0.5 mL), and tris-buffered saline (1 x 35 mL)• Items also available separately• Platelets in Cat. No. 5356 show a slower reaction rate

than platelets in Cat. No. 5371

Helena aPTT reagents are ready-to-use liquids for convenience, high quality for precision, and priced for economy. Reagents are suitable for photo-optical, mechanical and manual (tilt tube) methods.

5388 aPTT-SA & CaCl2, 250 tests, 5 x 5 mL5389 aPTT-SA & CaCl2, 500 tests, 5 x 10 mL5387 aPTT-SA, 1000 tests, 10 x 10 mL 5386 0.025 M CaCl2, 10 x 10 mL

Activated Partial Thromboplastin Time

aPTT-SA (Soluble Activator)• Soluble ellagic acid activator• Optical clarity, homogeneous suspension a plus for automated systems• Shorter activation time (~3 minutes vs. 5 minutes)

Plateletworks POC Platelet FunctionResults in 2 minutes with a standard cell counter!• Platelet Count • Platelet Inhibition• Platelet Aggregation • CBC • Efficient pre-surgical screen • Monitor anti-platelet therapies • Determine best use of transfusion resources • Uses traditional ADP and collagen agonists • No specialized training or equipment • Use whole blood at the point of care

Cascade® POC SystemPoint of Care for Whole Blood CoagulationThe Cascade POC analyzer and unique reagent system are useful in monitoring routine anticoagulants and the antithrombotic drugs used to treat angina, MI, stroke, deep venous thrombosis and pulmonary and arterial emboli. A built-in battery pack and QC lockout features make it ideal for use in the ER, cath lab, cardiac surgery, warfarin clinics and physician offices. Cascade POC offers a rapid POC assay for monitoring the anticoagulant effects of warfarin.

Testing is fast and easy:1. Swipe test card through reader.2. Insert card into analyzer and add sample.3. View final results in minutes

Cascade POC Assays• PT with INR (ISI ~ 1.0)

– PT-WB for fresh whole blood

– PT-C for citrated whole blood or plasma

• aPTT for citrated whole blood or plasma

• c-ACT for fresh whole blood

Actalyke POC Heparin AssessmentActivated Clotting Time

• 2-point early clot detection• Single and dual well models• Extensive data handling• Celite, Kaolin, Glass or MAX-ACT tests

Book M8/11(4)

800-231-5663•www.helena.com

Documents

Plateletworks POC Platelet Function