Physiology - MCQ Bank[1]

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1.Thecarotidbodies:a)havealowbloodflowpergram

oftissueb)containbaroreceptorsc)respondtochangesinpHd)respond

tosmallchangesinPaO

2e)arelocatedonthe

externalcarotidarteries

2.Thefollowingareexamplesofactivetransport:

a)sodiumextrusion


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fromcellsb)waterreabsorptionfromthe

proximalconvolutedtubulec)potassiumexcretioninthedistalconvolutedtubuled)

glucoseabsorptionfromthegutc)waterreabsorptionintheloopofHenle

3.Growthhormoneandinsulinhaveoppositeeffectson:a)carbohydrateuptakebymuscleb)catabolismoffatc)synthesisoffatd)

synthesisofprotein


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e)somaticgrowth

4.Stimulation

ofthetenthcranialnervecauses:a)slowingofA-Vconductionb)

constrictionofcoronaryvesselsc)increasedsecretionofgastricacidd)miosise)

relaxationofthepylorus

5.Anincreaseinsympatheticstimulationtotheheartcauses:a)afallindiastolictimeb)afall

indP/dtc)


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anincreaseinstrokevolumed)dilation

ofthecoronaryvasculaturee)anincreaseinmyocardialoxygenconsumption

6.Ifoxygenisaddedtoinspiredairtoincreaseitspartial

pressurefrom20kPa(150mmHg)to60kPa(450mmHg):a)dissolvedoxygenwillincreaseapproximatelythree-foldb)theoxygencontentoftheblood

willincreaseapproximately


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three-foldc)thePaNwillremainthesame

2


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d)thePaOwill

increaseapproximatelythree-fold

2e)hypercarbiawillbeprevented

7.Pulmonaryvascularresistanceisincreasedby:a)serotoninb)hypocarbiac)

hypoxiad)afallinpHe)adrenaline

8.Onchangingfromtheuprighttothesupineposition:a)baroreceptoractivitydecreasesb)

legveinpressure


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isreducedc)thebloodvolumein

thepulmonarycirculationfallsd)strokevolumeincreasese)reninactivityincreases

9.Thefallinurineoutputassociatedwithmajortraumamay

becausedby:a)haemorrhageb)ariseinantidiuretichormoneactivityc)afallinaldosteroneactivityd)anincreaseinthelevelof

circulatingcatecholaminese)


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ariseincorticosteroidoutput

10.Inthefoetalcirculationbeforebirth:a)thePOishigherin

theductusvenosusthanintheductusarteriosus

2b)blood

cangofromtherightatriumtotheaortawithoutpassingthroughtheleftatriumandventriclec)thePOintheaorticarchishigher

thaninthe


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descendingaorta

2d)blood

flowingthroughtheforamenovalecomesprincipallyfromthesuperiorvenacava

e)bloodpassesthroughtheductusarteriosusbecauseofthehighpulmonaryvascular

resistance

11.Inthecentralvenouspressurewaveform:a)theawaveoccursafterventricularsystoleb)thevwaveiscausedby

atrialcontractionc)


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theawaveisabsentinatrial

fibrillationd)theawavecorrespondswithclosureoftheaorticvalve

e)thevwaveoccursduringdiastole

12.Reninactivityis

increasedby:a)anincreaseincirculatingadrenalineb)hypotensionc)increasedsodiumingestiond)anincreaseinaldosteroneoutpute)hypovolaemia

13.

Acuteantagonismof


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betaadrenergicreceptorscauses:a)hyperglycaemiab)

peripheralvasodilatationc)suppressionofuterinecontractility


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d)pupillarydilatation

e)areductionincardiacoutput

14.Unilateraltransectionof

dorsalnerverootsC3-T2produces:a)motorparalysisb)lossofsensationc)

lossofreflexesd)lossofsympatheticandsudomotortonee)hypotonia

15.Therateofgastricemptyingis:a)delayedbyfat

intheduodenum


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b)delayedbysecretinc)delayedby

fatintheoesophagusd)enhancedbyalcohole)independentofvolume

andtypeoffoodingested

16.Anincreaseinaldosteroneproduction

occursinresponseto:a)ingestionofsodiumchlorideb)anincreaseinbloodvolumec)anincreasedintakeofpotassiumd)angiotensinIIe)

trauma


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17.Cerebrospinalfluid:a)isthemain

sourceofbrainnutritionb)ismainlyproducedbyactivesecretionfrom

thechoroidplexusc)containsvirtuallynoglucosed)pHchangesrapidlyin

responsetochangesinplasmapHe)pressureincreaseswithjugularvenousobstruction

18.Carbonicanhydraseisfoundathighconcentrationin:a)

plasmab)red


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bloodcellsc)renaltubularcellsd)

gastricparietalcellse)cardiacmusclecells

19.TheHb-oxygen

dissociationcurveshiftstotherightin:a)acutehypoxiab)storedblood

c)metabolicacidosisd)respiratoryalkalosise)hypothermia

20.Thefunctionalresidualcapacity:a)isincreasedintheobeseb)isapproximately10%

higherinmen


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thaninwomenc)fallswithgeneral

anaesthesiad)increasesonchangingfromthesupinetothestandingposition


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e)fallswithincreasingageANSWERS1.FFTFF2.TFTTF3.TTTFF4.TFTFT5.TFTTT6.TFFTF7.TFTTF8.FTFTF9.TTFTT10.TTTFT11.FFTFT12.TTFFT13FFFFT14.FTTFF15.TTFFF16.FFTTT17.FTFFT18.FTTTF19.FFTFF20.FTTTTVisitwww.anaesthesiauk.comformorearticlesandpracticequestio

ns!


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Printthispage!PhysiologyMCQBank1Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!1.

Incalculatingtheshuntfraction,thefollowingneedtobemeasuredor

estimated:a)mixedvenousoxygencontentb)pulmonaryend-capillaryoxygencontentc)arterial

oxygencontentd)alveolarpartialpressureofoxygene)haemoglobinconcentration

2.Pulsepressureincreaseswithanincreasein:a)strokevolumeb)

leftventricularend-diastolic


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volumec)arterialpartialpressureofoxygen

d)systemicvascularresistancee)bloodviscosity

3.Acuteuntreated

haemorrhagicshockinapatientwillleadto:a)anincreaseinphysiological

dead-spaceb)anincreaseinthearterio-venousPCOdifference

2c)afallinthepulmonaryvascularvolumed)anincreaseinantidiuretichormone

secretione)an


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increaseinplasmabicarbonateconcentration

4.Anincreaseinaldosteronesecretionfollows:a)asodiumchlorideload

b)ariseinbloodvolumec)anincreaseinoralpotassiumabsorption

d)traumac)anincreaseinproductionofangiotensinII

5.Stimulationofalpha-adrenergicreceptorswillcause:a)vasoconstrictionofthecoronaryarteries

b)increasedtone


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inthebladderneckmusclec)increased

plateletaggregationd)lipolysise)bronchodilation

ANSWERS

1.TTTTT

2.TTFFF3.TFTTF4.FFTTT5.TTTFF


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Inthenormaladultheart:a)mitralvalveclosureoccursbeforetricuspid

valveclosureb)pulmonaryvalveclosureoccursbeforeaorticvalveclosurec)there

isisometriccontractionoftheleftventricleaftertheaorticvalveopensd)atrialcontractionisofmoreimportancetoventricularfillingiftheheart

rateincreasese)


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theaorticvalvecuspsareimmobileduring

ventricularfilling

7.Resistancetolaminarflowinavessel

is:a)proportionaltowallthicknessb)inverselyproportionaltothefourthpower

oftheradiusc)proportionaltolengthd)independentofhaematocrite)proportionaltothepressuredrop

8.Autoregulatorymechanismsusedinhypovolaemia

include:a)an


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increaseinprecapillarysphinctertoneb)an

increaseincapillaryhydrostaticpressurec)adecreaseinbaroreceptoractivityd)

stimulationofthejuxtaglomerularapparatuse)anincreaseinangiotensinII

9.Myocardialcontractilityisincreasedby:a)catecholaminesb)anincreaseinheartratec)anincreaseinfibrelengthd)anincreaseinparasympathetic

nervoussystemactivity


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e)calciumions

10.The

carotidsinuses:a)havestretchreceptorsintheirwallsb)giveafferent

impulsesviatheglossopharyngealnervec)stimulatetherespiratorycentred)containchemoreceptors

e)stimulatethevasomotorcentre

ANSWERS

6.TFFTT7.FTTFF8.TTTTT9.TTTFT10.TTFFT


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Thefollowingcauseadecreaseinthearterialpartialpressureofoxygen:

a)anaemiab)carbonmonoxidec)hyperventilationd)ariseinphysiologicaldead-space

e)oldage

12.Ironabsorptionisdependenton:a)totalbodyvitaminCb)HClinthestomachc)anintactcolonic

mucosad)total


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bodyirone)erythropoietinlevelsinthe

blood

13.Ifanormalpersonhyperventilatesfor2hours

toanarterialPCOof42kPa:

a)thecerebralblood

flowdecreasesb)thestandardbicarbonatedecreasesc)theHb-oxygendissociationcurveshiftstotheleftd)theionisedcalciumconcentrationdecreasese)theplasma

bicarbonateincreases


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14.Hypoglycaemiamayresultfrom:a)

excessiveinsulinsecretionb)alpha-adrenergicstimulationc)beta-adrenergicstimulationd)glucagonsecretion

e)hypothermia

15.Ingestedlipid:a)isimportantinprostaglandinsynthesis

b)increasesinthefaeceswithadecreaseinbilesecretionc)isabsorbedviatheintestinallymphaticsd)ismainlyintheformof

triglyceridese)can


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beusedasasourceofATP

production

ANSWERS

11.FFFFT12.FTFTF13.TFTTF14.TFTFF15.TTTTT


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Thefollowingmaybefoundinnormaladultvenousblood:a)3%

carboxyhaemoglobinb)5%methaemoglobinc)70%oxyhaemoglobind)2%freehaemoglobine)2%

fetalhaemoglobin

17.Innormalhumanlungs:a)alowPOproducespulmonaryvasodilatation

2b)beta-2agonistscausebronchoconstrictionc)pulmonary

vascularresistanceis


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increasedbyserotonind)pulmonaryvascularresistance

isdecreasedbyhistaminee)pulmonaryvascularresistanceisdecreasedbynoradrenaline

18.Thenormalresponsetosurgeryincludes:a)adecreasein

urinevolumeb)adecreaseintheurinaryexcretionofsodiumc)adecreaseinplasmacortisolleveld)anincreaseintheurinaryexcretion

ofnitrogene)


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anincreaseintheurinaryexcretionof

potassium

19.Capillarypermeabilityisincreasedby:a)bradykininb)

adrenalinec)calciumd)vasopressinc)histamine

20.Expectedchangesin

apatientwithaphaeochromocytomainclude:a)adecreasedhaematocritb)adecreasedtotalbloodvolumec)adecreasedserumsodiumconcentrationd)anabnormal

glucosetolerancetest


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e)areducedmetabolicrate

ANSWERS

16.TFTFF17.FFTFF18.TTFTT19.TFFFT20.FTFTF


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Theliver:a)receivesmostofitsoxygensupplyfromtheportal

veinb)hasitshighestoxygentensionatthecentreofalobule

c)producesheparind)hasanormalportalvenouspressureofgreaterthan20mmHge)receivesapproximately25%ofthecardiacoutput

2.Skeletalmuscle


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bloodflow:a)increaseswithnoradrenalineb)

receives50%ofthecardiacoutputatrestc)mayceaseduring

isometriccontractiond)increaseswithrhythmiccontractione)increaseswithadrenaline

3.Inthermoregulation:a)respiratoryheatlossisinsignificantundernormalconditionsb)brownfatisanimportantsourceofheatproductioninneonatesc)

shiveringisdue


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toimpulsesconductedviaautonomicefferentsd)

peripheralvasoconstrictionincreasesheatproductione)sweatingismediatedbysympatheticcholinergic

neurones

4.Adrenaline:a)issynthesizedbydemethylationofnoradrenalineb)

increasescoronarybloodflowc)increasesfreefattyacidsinthebloodd)mobilizesglycogenstoresfromthelivere)ismetabolizedintheplasma

bymonoamineoxidase


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5.Glucagon:a)isa

positiveinotropeb)isproducedbythebetacellsofthepancreas

c)stimulatesproductionoffreefattyacidsinthebloodd)releaseis

increasedinstarvatione)stimulatesglycogensynthesis

ANSWERS

1.TFTFT2.FFTTT3.TTFFT(fundamentalsofanaesthesia,2ndeditionpage446)4.FTTTF5.TFTTF


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Surfactant:a)isamucopolypeptideb)causesadecreaseinsurfacetension

c)resultsinthesamesurfacetensionfordifferentsizedalveolid)causes

anincreaseincompliancee)productionisreducedafteraprolongedreductioninpulmonarybloodflow

7.Sinusarrhythmia:a)producesalengthening

oftheP-R


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intervalb)producesalengtheningofthe

R-Rintervalc)ismaximalwithbreathholdingd)ismoremarked

duringexercisee)ismoremarkedin70yearoldsthanin20

yearolds

8.Apressure-volumecurvecanbeusedformeasuring:a)theworkofbreathingb)functionalresidualcapacityc)anatomicaldead

spaced)compliance


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e)respiratoryquotient

9.The

absoluterefractoryperiodforcardiacmuscleis:a)aslongasthe

entireactionpotentialb)theperiodwhennofurtheractionpotentialcanbe

stimulatedc)twicethelengthoftheS-Tintervald)aslongasthemechanicalcontractione)shorterforpacemakertissuethanfornormalcardiac

muscle


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10.Inayoungnormaladult:a)

theglomerularfiltrationrateisapproximately125ml/minb)the24hour

urinecreatininecontentisapproximately800mgc)urinespecificgravityisalways

lessthan1000d)renalbloodflowisapproximately20%ofcardiacoutpute)over50%ofwaterreabsorptionfromtheglomerularfiltrateoccursin

thecollectingducts


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ANSWERS

6.FTFTT7.FTFFF

8.TFFTF9.FTFFT10.TFFTF


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Totalplasmacalcium:a)increaseswithphosphateb)increaseswitharise

inalbumin,c)changesitsdegreeofionisationwithpHchangesd)is

decreasedinosteoporosise)isaffectedbyvitaminD

12.Thereisincreasedintestinalmotilitywith:a)increasedintraluminalpressureb)anticholinesterasedrugs

c)sympatheticblock


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toT4d)stimulationofthesplanchnic

nervese)increasedcirculatingadrenaline

13.Ahealthyadultbreathing

anFIOof0.1will:2

a)haveadecreasedcardiacoutput

b)haveanormalPaO

2c)haveachangedalveolarPCO

2d)haveanunchangedrespiratoryratee)initiallyhavea

fallinpH


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14.Acetylcholineisaneurotransmitter

at:a)sweatglandsb)theadrenalmedullac)theparotidgland

d)parasympatheticgangliae)theneuromuscularjunction

15.Insulin:a)has

thesameeffectonbloodsugarasgrowthhormoneb)inhibitsentryofpotassiumintocellsc)facilitatesproteinanabolismd)increasesdepositionoffats

e)secretionis


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affectedbycatecholamines

ANSWERS

11.FTTFT12.TTTFF13.FFTFF14.TTTTT15.FFTTT


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Inanormalrestingsubject,abradycardiawouldbeexpectedfollowing:a)

anincreaseincarotidsinuspressureb)anincreaseinrightatrialpressure

c)applicationofpressuretotheeyeballd)thereleaseofaValsalvamanoevree)inspiration

17.Thevelocityofconductionofa

nerveactionpotential:


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a)isinverselyrelatedtothecross-sectional

areaoftheaxonb)isfasterinamyelinatedfibrethan

inanunmyelinatedonec)isdecreasedbycoolingthenerved)can

exceed100m/sinhumanse)ishighestinpre-ganglionicautonomicfibres

18.Theplacenta:a)transportsglucosefrommaternaltofoetalblood

byfacilitateddiffusion


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b)cansynthesizeglycogenc)activelytransports

oxygenfrommaternaltofoetalbloodd)allowsproteinmoleculestopass

frommaternaltofoetalbloodbypinocytosise)secretesoestradiol

19.

Oxytocin:a)stimulatesproductionofmilkb)stimulatesejectionofmilkc)releaseisstimulatedbydilatationofthecervixd)issynthesizedinthe

anteriorpituitarye)


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producesmorepowerfuluterinecontractioninthe

presenceofprogesterone

20.Aldosterone:a)productionincreaseswitha

fallinplasmaosmolalityb)productiondecreaseswithafallinbloodvolume

c)productiondecreaseswithariseinplasmareninleveld)increasesurinarypotassiumexcretione)maybeproducedbytumoursoftheadrenalcortex

ANSWERS


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16.TFTTF17.FTTTF18.TFFFT19.FTTFF20.FFFTT


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Adrenalinea)issecretedbytheadrenalcortexb)decreasessystemicvascular

resistanceatlowdosesc)decreasespulmonaryvascularresistanced)constrictsthepupil

e)actsonlyatbeta-1receptors

2.Atypicalmammalianmotorneurone:a)innervatesonlyoneskeletalmusclecellb)ismyelinatedc)

hasitscell


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bodyintheventral(anterior)hornof

thespinalcordd)mightreceiveaninputdirectlyfromGroupIa

afferentfibresinthespinalcorde)wouldbestimulatedbyapplicationof

glycinetoitscellbody

3.Thevagusnerve:a)haslittledirecteffectonthestrengthofventricularcontractionb)containsafferent

andefferentfibres


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c)containsparasympatheticpost-ganglionicfibresd)contains

fibreswhichregulategastricacidsecretione)hasaroleinbladder

emptying

4.Vitalcapacity:a)isthevolumeofairexpired

fromfullinspirationtofullexpirationb)increasesgraduallywithageinadultsc)isgreaterinmenthaninwomenofsimilarageand

heightd)is


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equaltothesumoftheinspiratory

andexpiratoryreservevolumese)maybemeasuredbyspirometry

5.Hyperventilationinanormalsubjectfor24hourswillproducea:a)

fallinPaCO

2b)riseinPaCO

2c)riseinionisedcalciumd)fallincerebrospinalfluidbicarbonatee)risein

plasmabicarbonate


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ANSWERS

1.FTTFF2.FTTTF3.TTFTF

4.TFTFT5.TFFFF


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Printthispage!PhysiologyMCQBank10Visitwww.anaesthesiauk.comformorearticlesandpracticequestions!

6.Theblood-brainbarrier:a)resultsincertainmoleculesintheblood

takinglongertoequilibratewithtissuefluidinthebrainthanwithtissue

fluidelsewhereb)permitsCOtopassfreely

2c)ismorepermeabletowater-solublesubstancesthanfat-solublesubstancesd)ismorepermeablein

neonatesthanin


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adultse)isreadilycrossedbydopamine

7.Areflexaction:a)maybecarriedoutby

skeletal,smoothorcardiacmuscleorbyglandsb)isnotinfluencedby

highercentresinthebrainc)resultsfromactivityinatleasttwocentralnervoussynapsesinseriesd)mayinvolvesimultaneouscontractionofsome

skeletalmusclesand


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relaxationofotherse)canbemonosynaptic

orpolysynaptic

8.Platelets:a)areproducedinthebone

marrowb)increaseinnumberaftertissuedamagec)haveasmallnucleus

d)altertheirshapewhentheymakecontactwithcollagene)areactivatedbyADPandthrombin

9.Thepressure:a)dropacross

themajorveins


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issimilartothatacrossthemajor

arteriesb)dropacrossthehepaticportalbedissimilartothat

acrossthesplenicvascularbedc)inthehepaticportalveinishigher

thanthatintheinferiorvenacavad)dropacrossthevascularbedinthefootisgreaterwhenstandingthanwhenlyingdowne)

dropacrossthe


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pulmonarycirculationisthesameasacross

thesystemiccirculation

10.Athletesdifferfromnormalindividualsin

having:a)ahigherrestingcardiacoutputb)ahigherrestingheartrate

c)adecreasedmusclemassd)ahighermaximumoxygenconsumptione)increasedmuscularefficiencyathighbloodlactatelevels

ANSWERS

6.TTFTF7.TFFTT8.TTFTT


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9.FFTFF10.FFFTT


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1.Stimulationoftheparasympatheticnervoussystem:a)increasestheheartrate

b)decreasestherateofgastricemptyingc)dilatesthepupild)causes

vasoconstrictione)causescontractionofthedetrusormuscleinthebladder

2.Pregnancyattermisassociatedwitha:a)20%decreasein

redcellmass


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b)riseincardiacoutputc)fall

inPaCO

2d)fallinhaematocrite)lowprotein-boundiodine

3.TheP5Ois:a)theoxygensaturationwhenthearterial

partialpressureofoxygenis50mmHgb)thearterialoxygentensionwhenhaemoglobinis50%saturatedc)anindicatorofthepositionofthe

oxygendissociationcurve


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d)raisedinfoetalbloode)lowered

inchronicanaemia

4.Inahealthyadulthumanheart

the:a)leftventricularend-systolicvolumeisapproximately30mlb)firstheart

soundcoincideswiththeonsetofventricularsystolec)strokevolumeisapproximately70mld)leftventricularend-diastolicpressureisabout50mmHge)

secondheartsound


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iscausedbyclosureoftheaortic

andpulmonaryvalves

5.Renin:a)isreleasedfromgranules

inthejuxtaglomerularcellsoftheafferentarterioleb)levelsintheblood

increaseinresponsetoafallinplasmasodiumconcentrationc)levelsintheblooddecreasewhenrenalperfusionisdecreasedd)releaseisenhanced

byangiotensinII


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e)releaseisinhibitedbyantidiuretichormone

ANSWERS

1.FFFFT2.FTTTF3.FTTFF4.TTTFT5.TTFFT


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1.Thefollowingaresecretedfromtheadrenalcortex:a)testosteroneb)

aldosteronec)angiotensind)noradrenalinee)deoxycorticosterone

2.Aldosterone:a)secretion

increasesinresponsetoafallinbloodvolumeb)isapolypeptidec)producesanincreaseinrenalarterialpressured)producesafall

inurinevolume


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e)increasesthereabsorptionofsodium

3.Cerebrospinalfluid:a)isactivelysecretedbythechoroidplexus

b)isthemajornutritionsourceofthebrainc)hasthesame

pHasarterialbloodd)containsvirtuallynoglucosee)hasahigherchloridelevelthanplasma

4.Redbloodcellproduction:a)

increasesduringacclimatisation


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toaltitudeb)canoccurinthe

spleenc)isdependentonnormalgastricsecretoryactivityd)isstimulated

byhypercarbiae)isdependentonervthropoietin

5.Bile:a)salts

contributetothesolubilityofcholesterolinthebileb)containsbilirubinmainlyintheunconjugatedformc)contributesmorethanpancreaticsecretiontothe

neutralisationofacid


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fromthestomachd)becomesmorealkaline

followingconcentrationinthegallbladdere)isproducedatarate

ofapproximately2000ml/day

ANSWERS

1.FTFFT2.TFTFT3.TFFFT4.TTTFT

5.TFFFF


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1.Carbonicanhydraseplaysaroleinthe:a)productionofHCl

bytheparietalcellsofthestomachb)secretionofhydrogenionsfrom

thefluidintherenaltubulesc)passageofCOfromthepulmonarycapillariestothealveoli

2d)secretionofbicarbonatebythe

pancrease)production


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ofredbloodcells

2.

Inapatientwithseverehypovolaemia,the:a)physiologicaldead-spaceincreasesb)

arterio-venousoxygendifferencedecreasesc)alveolar-arterialoxygendifferenceincreasesd)minutevolumeincreases

e)arterialPCOincreases

2

3.ThegroupAantigen:a)ispresentontheredcellsofagroupApatient

b)mayoccur


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inthesalivaofagroupA

patientc)istransmittedasanautosomalrecessivecharacteristicd)ismore

commonthanthegroupBantigene)isthemostcommoncauseof

haemolyticdiseaseofthenewborn

4.Theactionofnoradrenalinemaybeterminatedby:a)monoamineoxidaseinthenerveterminalb)catechol-O-methyltransferasein

theliverc)


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catechol-O-methyltransferaseinthenerveterminald)dopa

decarboxylaseinthenerveterminale)neuronalreuptake

5.An

increaseinthe2.3-DPGconcentrationinredbloodcellsoccursin:a)anaemia

b)acclimatisationtoaltitudec)storedbloodd)trainedathletese)cyanoticheartdisease

ANSWERS

1.TTFFF2.TFTTF3.TTFTF4.TTFFT5.TTFFT


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1.Innormalcerebrospinalfluid,the:a)chlorideconcentrationishigherthan

inbloodb)glucoseconcentrationisthesameasinplasmac)PCOis

higherthaninmixedvenousblood

2d)pHisthesameasinarterialbloode)bicarbonateconcentrationisthesameas

inarterialblood


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2.Whenbreathingoutagainst

aclosedglottis,the:a)intratrachealpressurerisesb)heartrateslows

transientlyc)rightventricularoutputincreasesd)leftventricularoutputhasasustained

increasee)systolicarterialpressurefallsthenrises

3.Changingpositionfromstandingtosupine:a)increasesstrokevolumeb)increasesbaroreceptoractivity

c)increasesthe


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pulmonarybloodvolumed)decreaseslegvein

pressuree)decreasestheheartrate

4.Vagalstimulationproduces:

a)afallinheartrateb)anincreaseinatrialcontractilityc)

anincreaseinventricularcontractilityd)slowingofA-Vconductione)afallinstrokevolume

5.Thefollowingarerepresentativeofmyocardial

afterload:a)mean


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aorticpressureb)meanpulmonaryarterypressure

c)leftventricularend-diastolicvolumed)leftventricularend-diastolicpressuree)the

rateofriseofleftventricularpressure

ANSWERS

1.TFTFF

2.TTFFF3.TTTTT4.TFFTT5.TTFFF


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Printthispage!PhysiologyMCQBank161.Onascendingtoanaltitudeof6000m,changesinclude:

a)anincreaseinminutevolumeb)aninitialincreaseinplasmapHc)ariseinurinepHd)afallinarterialPO2e)anincreaseincerebralbloodflow2.Transferrinis:a)involvedinironuptakebythegutmucosab)involvedinirontransportacrossthegutmucosac)involvedinirontransporttomuscled)involvedinirontransporttostoragesitese)normallyonly35%saturatedwithiron3.Breathing100%oxygenatatmosphericpressureforaprolongedperiodcauses:a)retrosternalpainb)dizzinessc)auditorydisturbancesd)convulsionse)atelectasis4.Thefollowingtransfusionswillleadtoagglutination:5.Chemoreceptorsinthearterialsystem:a)haveahigherrateofoxygenconsumptionpergramthanbraintissueb)respondtochangesinoxygentensionandnotcontentc)respondtochangesinpHd)conductafferentinformationviatheglossopharyngealandvagusnervese)arefoundinthecarotidsinusANSWERS1.TTTTF2.FFTTT3.

TFFFT4.TTFFT5.FTTTFDonorRecipienta)BOb)ABAc)BABd)OABe)ABOVisitwww.anaesthesiauk.comformorearticlesandpracticequestions!


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1.Inthehealthyheart,anincreaseinstrokevolumeisseen

withanincreasein:a)dP/dTb)aorticsystolicpressurec)leftventricular

end-diastolicvolumed)leftventricularend-systolicpressuree)heartrate

2.Thea-waveofthecentralvenouspressurewaveform:a)iscausedby

atrialcontractionb)


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isnotseeninatrialfibrillationc)

iscausedbyatrialfillingduringventricularcontractiond)decreaseswithinspiration

e)isfollowedbythev-wave

3.Intheelectrocardiogram,the:

a)P-RintervalisequivalenttotheA-Vnodalconductiontimeb)T-waveisequivalenttoventricularrepolarisationc)Q-Tintervalisequivalenttothe

durationofventricular


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contractiond)U-waverepresentssinoatrialnoderepolarisation

e)durationofanormalP-waveis0.2seconds

4.

Ptosisresultsfrom:a)parasympatheticblockb)sympatheticblockc)facialnerveblock

d)trigeminalnerveblocke)oculomotornerveblock

5.Thefollowingareprecursorsofadrenaline:a)tyrosineb)phenylalaninec)noradrenalined)dopamine

e)isoprenaline


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ANSWERS

1.TFTFF2.TTFFF3.TTTFF

4.FTTFT5.TTTTF


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1.Thefollowingleadtoanincreaseininsulinsecretion:a)glucagon

b)adrenalinec)growthhormoned)starvatione)majortrauma

2.

Adenylcyclase:a)increasestheconversionofATPtocyclicAMPb)iscloselylinkedtoalpha-andbeta-adrenergicreceptorsc)isinhibitedbyaminophyllined)

releaseistriggered


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bycyclicAMPe)actsata

mitochondriallevel

3.Surfactant:a)containsphospholipidsb)preventsoedema

formationinthealveolarwallc)reducessurfacetensionbyapproximately30%d)

producesamonomolecularlayere)stabilisesthesizeofanalveolus

4.Theoxyhaemoglobindissociationcurveisshiftedtotheleftby:a)

anincreasein


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arterialPCO

2b)acidosisc)

chronicanaemiad)carbonmonoxidee)afallintemperature

5.Intheadult,growthhormonestimulates:a)glucoseuptakeintocellsb)

calciumabsorptionfromthegutc)proteinsynthesisd)fatsynthesise)bonegrowth

ANSWERS

1.TFTFT2.TTFFF3.TTFFT4.FFFTT5.FFTFT


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Documents

Physiology - MCQ Bank[1]