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Physical activity validation pilot project in Inuit of the Baffin reglon Daneen Dénommé School of Dietetics and Human Nutrition McGili University Montreal, Canada Submitted June 2006 A thesis submitted to McGili University in partial fulfillment of the requirements of the degree of Master of Science in Nutrition © Daneen Dénommé, 2006

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Page 1: Physical activity validation pilot project in Inuit of the ...collectionscanada.gc.ca/obj/thesescanada/vol2/QMM/TC-QMM-99333.pdfsince the 1980's. The Physical Activity Monitor (PAM)

Physical activity validation pilot project in Inuit of the Baffin reglon

Daneen Dénommé

School of Dietetics and Human Nutrition McGili University Montreal, Canada

Submitted June 2006

A thesis submitted to McGili University in partial fulfillment of the requirements of the degree of Master of Science in Nutrition

© Daneen Dénommé, 2006

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Abstract

The main goal of this study was to evaluate the utility of physical activity

(PA) measurement in an Inuit population with a self-administered

questionnaire. The objective was to validate a culturally relevant physical

activity questionnaire that measures Inuit PA levels. To do this, the

International Physical Activity Questionnaire (IPAQ) was evaluated against

the Caltrac accelerometer and anthropometrie/physiologie measurements.

There were a number of compliance problems encountered when

implementing the Caltrac in the pilot community which resulted in too few

Caltrac scores available for analyses. However, IPAQ PA score (N=44)

was significantly inversely related to Body Mass Index (P.:::O.05) and

positively related to high-density lipoprotein cholesterol (p.:::O.03).

The results indicate that the IPAQ has potential but needs further

refinements to be acceptable to Inuit populations and needs re-evaluation

in a larger sample. The participants found it very difficult to remember the

time spent performing each activity and, in general, the IPAQ was not weil

received.

i

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Résumé

Le but principal de cette étude était de déterminer l'utilité d'un

questionnaire auto-administré pour estimer l'activité physique (AP) des

populations Inuit. L'objectif spécifique était de valider un questionnaire

adapté culturellement pour estimer les niveaux d'AP des Inuit. Ainsi, le

Questionnaire International de l'Activité Physique (IPAQ) a été comparé

avec l'accéléromètre Caltrac et des valeurs anthropométriques et

physiologiques.

Plusieurs problèmes sont survenus lors de l'utilisation du Caltrac dans la

communauté cible. Ceci a eu pour effet de diminuer le nombre de

résultats disponibles pour le Caltrac et d'empêcher l'analyse de ceux-ci.

Cependant, le score AP du IPAQ (N=44) était un déterminant significatif

de l'indice de masse corporelle (p~O.05) et des lipoprotéines de haute

densité (p~O.03).

Selon les résultats obtenus, le IPAQ démontre un certain potentiel mais il

nécessite des améliorations afin d'être mieux adapté aux populations Inuit.

Une réévaluation doit aussi être effectuée avec un plus grand échantillon.

Les participants avaient de la difficulté à déterminer le temps associé à

chacune des activités et en général, le IPAQ n'a pas été bien accepté.

ii

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Acknowledgments

Thank you to my supervisors, Dr. Grace Egeland and Dr. Harriet Kuhnlein

for giving me the opportunity to work on this project and for having the

patience to provide guidance throughout the work. 1 feel very privileged to

have spent the last two years at McGili under their supervision. 1 sincerely

feel that the knowledge 1 have gained from this project will be

indispensable in my future endeavours.

1 would like to say a special thank you to my committee member, Mr.

Hugues Plourde. 1 am very grateful for the expertise and insight that he

has brought to this project and 1 especially appreciated his dependability.

This project would not have been possible without the cooperation and

commitment from the Pangirtung Steering Committee who are: Jonah

Kilabuk, Markus Wilcke, Johnny Kuluguqtuq, Donna Kilabuk and our

advisor from Inuit Tapiriit Kanatami, Looee Okalik. Also, 1 would like to

thank our community research assistants: Jojo, Susa, and Emily for

explaining the Caltracs and conducting the interviews. A heartfelt thank

you goes to the committee members and to the study participants for so

graciously accepting us into their community and their personal lives. The

time that 1 spent with them was definitely the highlight of this project.

1 would never have been able to get through this program without the

amazing support of my friends and family. Thank you for ail of the

encouragement, understanding, and most importantly, for ail of the fun

times! 1 am so happy to have shared this experience (and city!) with you.

iii

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Table of Contents

Table of Contents ..................................................................................... iv

List of Tables ............................................................................................. vii

List of Figures .......................................................................................... viii

Introduction .............................................................................................. 1

1 Literature Review ................................................................................ 3

1.1 Inuit .............................................................................................. 3

1.1.1 Cultural Transition of Inuit ........................................................ 3

1.1.2 Changes in Aboriginal Peoples' Health .................................... 3

1.2 Overweight and Obesity .............................................................. 4

1.2.1 Health Risks ............................................................................. 4

1.2.2 Quality of Lifel Monetary Costs of Obesity ............................... 4

1.3 Overview of Prevalence of Overweight and Obesity .................... 5

1.3.1 International Trends ................................................................. 6

1.3.2 Canadian Trends ...................................................................... 6

1.4 Determinants of Obesity .............................................................. 7

1.4.1 Role of Physical Activity ........................................................... 7

1.4.2 Role of Diet .............................................................................. 8

1.4.3 Role of Genetics ....................................................................... 8

1.5 Benefits of PA .............................................................................. 9

1.5.1 PA Recommendations ............................................................. 9

1.6 PA Reported in Canada ............................................................. 10

1.7 Why Focus on PA Assessment? ............................................... 10

1.8 Measuring PA ............................................................................ 11

1.8.1 Objective Measures ., ............................................................. 12

1.8.2 Self-Reported Measures ........................................................ 16

1.8.3 Combination Methods ............................................................ 17

1.9 Available Questionnaires ........................................................... 18

1.9.1 The International Physical Activity Questionnaire (lPAQ) ...... 18

1.9.2 The Modifiable Activity Questionnaire (MAQ) ........................ 19

1.9.3 The Canadian Community Health Survey (CCHS) ................. 19

iv

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1.10 Cultural Considerations when Measuring PA ............................ 20

1.11 Questionnaire Validation ............................................................ 21

1.11.1 Indirect Indicators of Physical Health and Activity .............. 21

1.11.2 Methods of Validating Questionnaires ................................ 22

2 Community of Focus ......................................................................... 23

3 Specifie Goal and Objective .............................................................. 23

4 Significance of Study ........................................................................ 24

5 Subjects and Methods ...................................................................... 24

5.1 Ethics Approvals and Participatory Processes .......................... 24

5.2 Participant Recruitment ............................................................. 25

5.3 Sample Size .............................................................................. 25

5.4 Component 1: IPAQ Modification .............................................. 26

5.5 Component 2: PA Measurement ............................................... 27

5.6 Data Collection .......................................................................... 27

5.6.1 IPAQ ...................................................................................... 27

5.6.2 Caltrac Activity Monitor .......................................................... 27

5.6.3 Anthropometrie/physiologie reference indicators of PA .......... 28

5.7 IPAQ Data Scoring .................................................................... 28

5.8 IPAQ Data Entry ........................................................................ 29

5.9 IPAQ Data Cleaning .................................................................. 30

5.10 IPAQ PA Continuous Score ....................................................... 30

5.11 IPAQ PA Categorical Score ....................................................... 30

5.12 Canadian Recommendations .................................................... 31

5.13 IPAQ Sitting Question ................................................................ 32

5.14 Caltrac Activity Monitor .............................................................. 32

6 Results .............................................................................................. 34

6.1 Participant Characteristics ......................................................... 34

6.2 Background Analyses ................................................................ 34

6.3 IPAQ PA Analysis ...................................................................... 35

6.4 IPAQ Sitting Question ................................................................ 35

6.5 IPAQ vs. Canadian Recommendations ..................................... 36

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6.6 Caltrac ....................................................................................... 36

7 Discussion ........................................................................................ 38

8 Conclusion and Summary ................................................................. 42

9 Future Recommendations ................................................................. 43

Bibliography ............................................................................................. 45

Tables ...................................................................................................... 58

Figures ..................................................................................................... 64

APPENDiCES ..... ..................................................................................... 69

Appendix 1: McGili University ethics certificate ..................................... 70

Appendix 2: Nunavut Community-CINE research agreement. ................ 71

Appendix 3: Pangnirtung health screening informed consent forms in

English and Inuktitut. ..... ........................................................................... 72

Appendix 4: Physical activity validation study informed consent forms in

English and Inuktitut. .... ............................................................................ 73

Appendix 5: International Physical Activity Questionnaire (IPAQ) in

English and Inuktitut. ................................................................................ 74

vi

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List of Tables

Table 1. Gender and age distribution of participants (N=44) ................ 58

Table 2. Pearson and partial correlation coefficients of IPAQ PA

scores and anthropometrics (N=44) ................................................ 59

Table 3. 8eta coefficients and standard errors (SE) from linear

regressions of IPAQ physical activity scores predicting

anthropometrics .......... , .......... '" ................................................. 60

Table 4. Pearson and partial correlation coefficients of IPAQ Sitting

scores and anthropometrics (N=44) ................................................. 61

Table 5. 8eta coefficients and standard errors (SE) from linear

regressions of IPAQ Sitting scores predicting anthropometrics ............ 62

Table 6. Female and male participants who met Canadian PA

recommendations and those who did not, divided by IPAQ categorical

scores of high, moderate, and low .................................................. 63

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List of Figures

Figure 1. Box-plot showing total cholesterol outliers ......................... 64

Figure 2. Box-plot showing triglyceride outliers ................................ 64

Figure 3. Box-plot showing heart rate outliers .................................. 65

Figure 4. Scatter plot of HDL-cholesterol studentized residuals versus

HDL-cholesterol standardized predicted values ................................. 65

Figure 5. Scatter plot of BMI studentized residuals versus BMI

standardized predicted values ....................................................... 66

Figure 6. Scatter plot of ISI studentized residuals versus ISI

standardized predicted values ....................................................... 66

Figure 7. Histogram of HDL-cholesterol studentized residuals ............. 67

Figure 8. Histogram of BMI studentized residuals ............................. 67

Figure 9. Histogram of ISI studentized residuals .............................. 68

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1 ntrod uction

Overweight and obesity are significantly associated with many life­

threatening chronic diseases which can lead to disability and death.

These diseases include type 2 diabetes, hypertension, high cholesterol

(Kumanyika, Jeffrey, Morabia, Ritenbaugh, & Antipatis, 2002; Mokdad et

aL, 2003; World Health Organization, 2000), stroke, certain (Kumanyika et

aL, 2002; World Health Organization, 2000), arthritis, gastrointestinal

diseases (World Health Organization, 2000), asthma, gallbladder disease,

skin problems, and infertility (Kumanyika et aL, 2002). Beyond the

physical afflictions, psychosocial disorders such as clinical depression and

low self-esteem have been associated with overweight and obesity

(Kumanyika et aL, 2002).

Unbalanced diets and physical inactivity are two of the leading

causes of overweight and obesity (World Health Organization/Food and

Agriculture Organization, 2002). It is thought that by improving dietary

habits and increasing physical activity (PA) patterns, there exists the

potential to reverse the obesity epidemic (Prentice et aL, 2004). Although

these two lifestyle components hold equal importance in determining

health, dietary habits have been more widely studied than PA patterns. It

is thus very important to now make global PA monitoring a priority

(Bauman & Craig, 2005). In order to monitor PA patterns, it is essential to

develop and test the reliability and validity of PA measurement tools.

Canadian leisure-time PA patterns have been monitored frequently

since the 1980's. The Physical Activity Monitor (PAM) (Canadian Fitness

and Lifestyle Research Institute, n.d.) was used to collect data 12 times

between 1981 and 2004 and the Canadian Community Health Survey

(CCHS) (Health Canada, 2005) has been completed twice since 2000.

Until 1998 however, the PAM did not survey the northern territories. There

are limited data available on Inuit PA patterns. There is also a lack of

1

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culturally relevant questions used in these two surveys. For example, both

surveys only measured leisure-time PA by providing a list of activities that

included activities such as gardening, rollerblading, and golfing. These

are examples of activities that are infrequently performed in the North due

to environmental conditions. It can be argued that these surveys fail to

capture true PA patterns of Inuit populations due to lack of cultural

relevance.

Given the importance of PA monitoring, a pilot Inuit study was

conducted to help indicate the usefulness of a PA questionnaire.

2

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1 Literature Review

1.1 Inuit

Inuit are Aboriginal People of the Canadian Arctic with the majority

of the population living above the 50th parallel. The word "Inuit" means

"the people" in Inuktitut (Natural Resources Canada, 2004). In Nunavut,

the population is 85 percent Inuit (Centre for Research and Information on

Canada, 2002; Natural Resources Canada, 2004). Sixty-two percent of

the Canadian Inuit live in Nunavut and in the Northwest Territories, 21

percent live in Québec, and 10 percent live in Labrador. Nunavut is the

largest territory with an area of 2 million square kilometers, but has the

lowest territorial population; in 2001, Nunavut's 26 communities were

inhabited by 29, 000 people (Government of Nunavut, n.d.). Half of

Nunavut's inhabitants are under the age of 22, which makes the

population the youngest in Canada (Government of Nunavut, n.d.).

1.1.1 Cultural Transition of Inuit

A wide variety of technological advances affected the Inuit's culture

and traditionallifestyle during the 20th century. Before gaining access to

trading companies such as the Hudson's Bay stores, 100 percent of Inuit

diet was derived from traditional food sources. Now, the majority of the

adult Inuit diet consists of market foods with traditional foods contributing

only 10 to 36 percent (Kuhnlein, Receveur, Soueida, & Egeland, 2004).

Also, most hunting and fishing is now carried out using snowmobiles,

outboard motorboats and ali-terrain vehicles (Natural Resources Canada,

2004).

1.1.2 Changes in Aboriginal Peoples' Health

Aboriginal people in Canada suffer from a disproportionate amount

of iIIness compared to other Canadians (MacMillan, MacMillan, Offord, &

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Dmgle, 1996). They have a higher risk of certain health conditions such

as diabetes, cervical cancer, infectious diseases, suicide, injuries, and

substance abuse (MacMillan et aL, 1996). The Aboriginal people of

Canada have been affected by a rapid dietary transition from traditional

foods to those highly processed and high in fat (Reading, 2003). The

dietary change has been a major factor in the global obesity epidemic

(World Health Organization/Food and Agriculture Organization, 2002) as

weil as the diabetes epidemic among Aboriginal populations (Reading,

2003).

1.2 Overweight and Obesity

1.2.1 Health Risks

Of ail of the diseases and conditions associated with overweight

and obesity, type 2 diabetes mellitus is particularly important as 90 percent

of type 2 diabetics are either overweight or obese (Kumanyika et aL,

2002). The risk of developing other diseases such as stroke,

hypertension, and heart disease also increases with insu lin resistance and

obesity (Kumanyika et al., 2002). While type 2 diabetes has not yet been

seen as a main health concern among Inuit populations (Young, Shrarer,

Shubnikoff, Szathmary, & Nikitin, 1992), a recent study in Greenland

showed a prevalence of newly diagnosed diabetes (Bjerregaard, 2003),

raising concerns in Canada regarding the need for prevention, discussion,

and surveillance.

1.2.2 Quality of Lifel Monetary Costs of Obesity

Obesity is a major contributor to the global burden of disease and

disability (Kumanyika et aL, 2002) and is the most common metabolic

condition in industrialized countries (Birmingham, Muller, Palepu, Spinelli,

& Anis, 1999). The World Health Organization (WHO) has claimed that

obesity should be seen as the main neglected health problem in today's

4

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society (World Health Organization, 2000) With this burden, extra

demands are made on health care services and it is reported that the

economic co st of obesity in developed countries such as the United

States, France and Australia ranges from two to six percent of ail health

care costs (Kumanyika et aL, 2002). In 1997, the direct medical co st of

obesity in Canada was 1.8 billion dollars, which represented 2.4 percent of

total health care costs (Birmingham et aL, 1999). From 1990 to 2020, the

global increase of disease burden, measured in Disability Adjusted Life

Years, is expected to increase from 41 percent to 60 percent (Kumanyika

et aL, 2002). In the same 30 year span, deaths due to non-communicable

diseases have been predicted to increase from 28.1 million to 49.7 million

per year and the largest increase in such deaths will be in developing

countries (Kumanyika et aL, 2002). Although under-nutrition and

infectious diseases are still major concems in developing countries,

overweight and obesity are increasing (World Health Assembly 57.17,

2004). There is also an increase in ethnie minorities in developed

countries (World Health Organization, 2001).

1.3 Overview of Prevalence of Overweight and Obesity

Obesity is a complex condition that affects children and adults and

is prevalent in both developed and developing countries (World Health

Organization, 2000). Body mass index (BMI) using Quetelet's index,

which is weight in kilograms over height in squared meters (kg/m2), is the

most common measure of overweight and obesity (Torrance, Hooper, &

Reeder, 2002). The WHO has classified adult overweight as a BMI of 25

or greater and obese as a BMI of 30 or greater (World Health

Organization, 2006). BMI is a simple method of assessment and allows

for between population comparisons (Raine, 2004). BMI does not take

into consideration body composition and should be used with caution

among certain subgroups of the population. These include elderly people,

youth who have not reached their full height potential, and athletes.

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1.3.1 International Trends

Obesity in industrialized nations has risen dramatically in Canada,

Finland, New Zealand, the United Kingdom, and the United States

between 1989 and 1998 (Raine, 2004). Globally, there are greater than 1

billion overweight adults and 300 million of these obese (World Health

Organization, 2006). In 2001, the Behavioral Risk Factor Surveillance

System (BRFSS) reported that 20.9 percent of adults in the United States

were obese (Mokdad et aL, 2003), which is a large increase, compared to

the results from the 1976-1980 NHANES reporting US adult obesity at

14.5 percent (Flegal, Carroll, Kuczmarski, & Johnson, 1998). When

examining younger populations, it is estimated that, globally, there are

approximately 22 million overweight children under the age of five

(Kumanyika et aL, 2002).

1.3.2 Canadian Trends

1.3.2.1 Adults

National population based surveys have shown an increase in the

prevalence of overweight and obesity among Canadians in the past two

decades (Raine, 2004). Between 1978 and 2004, obesity has increased

from 13.8 percent to 23.1 percent in Canada (Tjepkema & Shields, 2005).

ln 2004, another 36.1 percent were overweight (Tjepkema & Shields,

2005). When combined, these numbers tell us that over half of Canadian

adults do not have a healthy body weight.

1.3.2.2 Aboriginal Groups

ln the late 1980s, the prevalence of Aboriginal men and women of

ail age groups with BMI greater or equal to 26 was higher than other

Canadians (Young & Sevenhuysen, 1989). This difference has not

decreased in the last decade; according to the CCHS (2000-2001), obesity

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in the northern territories is higher than the national average (Statistics

Canada, 2002). More specifically, the average percentage of obesity in

men and women is 20.2 and 20.4 in Nunavut and 22.4 and 20.4 in the

Northwest Territories, respectively (Statistics Canada, 2005b). It is difficult

to examine overweight and obesity rates in younger Aboriginal populations

as there is very limited anthropometric data of Aboriginal children and

adolescents in Canada (Hanley et aL, 2000).

1.4 Determinants of Obesity

The roles of energy intake and energy expenditure on the

prevalence of overweight and obesity have not been absolutely defined,

but it is evident that an increase in positive energy balance is the major

cause (Bruce & Katzmarzyk, 2002; Flegal et aL, 1998; Katzmarzyk, 2002;

Raine, 2004). The WHO stated: "the fundamental causes of the obesity

epidemic are societal, resulting from an environment that promotes

sedentary lifestyles and the consumption of high-fat, energy-dense diets"

(World Health Organization/Food and Agriculture Organization, 2002).

Unfortunately, the relative contributions of the personal and behavioural

determinants of the Canadian obesity epidemic cannot be fully understood

as there is limited PA and food consumption surveillance data (Raine,

2004).

1.4.1 Role of Physical Activity

A decrease in energy expenditure through decreased physical

activity (PA) is likely one of the chief factors contributing to the obesity

epidemic (World Health Organization/Food and Agriculture Organization,

2002). Physical activity is a protective factor against overweight or obese

(Tremblay & Willms, 2003) and physical inactivity is associated with

increased risks of chronic disease (Pois, Peeters, Kemper, & Grobbee,

1998).

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1.4.1.1 Occupational and Transportation Activity

Technology developments have allowed for a decrease in energy

expenditure related to occupation and transportation (Kumanyika et aL,

2002; Montoye, 2000). As weil, there has been a decrease in daily labour

needs due to labour-saving technologies (Tremblay & Willms, 2003). Inuit

populations have also been witnessing these changes with ali-terrain

vehicles and snow machines being used as transportation when hunting

and fishing.

1.4.2 Role of Diet

The consumption of high fat, energy-dense diets is one of the major

contributors to the obesity epidemic (Raine, 2004; World Health

Organization/Food and Agriculture Organization, 2002). The global

availability of lower cost oils and fats, and other calorie-dense foods

(Tremblay & Willms, 2003) makes higher fat diets possible even in low­

income countries (Kumanyika et aL, 2002). With self-report measures,

there has been some evidence of a decrease in dietary fat intake in some

developed countries such as Canada, although no Aboriginals were

included in this study (Gray-Donald, Jacobs-Starkey, & Johnson-Down,

2000). It has been suggested however that underreporting and not a true

decrease could have been responsible for the decrease from such self­

reports (Kumanyika et aL, 2002).

1.4.3 Role of Genetics

It is thought that anywhere from 20 to 75 percent of body

composition and body weight variability within a population may be

attributed to genetics (Hill, Wyatt, & Melanson, 2000). While genetic

factors are important, the obesity epidemic has happened too quickly for

genetics to be the primary cause (Kumanyika et aL, 2002; Tremblay &

Willms, 2003; Vinicor, 2003). However, the gene-environment interaction

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may have a stronger influence on the emergence of obesity in certain

populations, such as Aboriginal populations (Raine, 2004).

1.5 Benefits of PA

PA can provide a means of improving the general health of the

majority of the population (VVu, Ronis, Pender, & Jwo, 2002). The

mediation of disease risk factors is thought to be part of the protective

effect of PA (Pois et aL, 1998). Cross-sectional studies show that PA is

negatively associated with obesity (Hill et aL, 2000). It has been shown to

be protective against certain diseases, such as certain types of cancer

(Lee & Paffenbarger, 1994), cardiovascular disease (Blair et aL, 1989),

premature death (Brage, Wedderkopp, Franks, Andersen, & Froberg,

2003), and hypertension (Arro Il & Beaglehole, 1992). Also, weight-bearing

exercise, which is assumed to increase bone mass will decrease

osteoporotic fractures (Pois et aL, 1998).

1.5.1 PA Recommendations

ln the Canadian Population Health Initiative (CPHI) 2004 report on

overweight and obesity prevalence, recommendations for eliciting health

benefits from PA is greater than 60 minutes of measured PA per day

(Raine, 2004). For adults who are already performing regular moderate

intensity activities, it is recommended that they also perform vigorous

intensity activity for 20 minutes at least three times per week (Kumanyika

et aL, 2002). The 1995 communication from the U.S. Centers for Disease

Control and Prevention and the American College of Sports Medicine

(Pate et aL, 1995) as weil as the 1996 U.S. Surgeon General's Report

recommended the accumulation of 30 minutes or more of moderate

intensity PA on most days of the week (U.S. Department of Health and

Human Services, 1996). These recommendations were designed to be

used along with previous recommendations of 20 to 60 minutes of

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moderate to high intensity endurance exercise at least three times weekly

(Pate et aL, 1995). It is thought that the new recommendations will

provide the same health benefits (Hendelman, Miller, Baggett, Debold, &

Freedson, 2000), as weil as allow the public to accumulate the 30 minutes

in separate segments throughout each day (Pate et aL, 1995), which is a

more attainable goal for most people (Hendelman et aL, 2000).

1.6 PA Reported in Canada

The number of Canadians who are physically active in their leisure

time has steadily increased between 1994 and 2003. However, the 1998-

1999 National Population Health Surveys (NPHS) reported that 76.6

percent of women and 73.9 percent of men were insufficiently active

(activity energy expenditure <3.0kcallkg/day) to reap health benefits

(Raine, 2004) and from the CCHS 2003, only 24 percent of Canadians

were reported to be sufficiently active by the same definition (Statistics

Canada,2005b).

1.7 Why Focus on PA Assessment?

It is thought that changes to dietary habits and PA patterns have

the potential to reverse the obesity epidemic (Prentice et al., 2004).

Although these two lifestyle components hold equal importance in

determining health, dietary habits have been more widely studied than PA

patterns. Since physical inactivity is considered to be a current global

health concern (Craig et aL, 2003) and has become a main focus for

public health policy makers (Craig, Russell, & Cameron, 2002). It is thus

very important to prioritize PA monitoring and the development PA

assessment tools to allow for the creation of accurate public health

recommendations.

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Canadian leisure-time PA patterns have been monitored quite

frequently since the 1980's. The Physical Activity Monitor (PAM) was

used to collect data 12 times between 1981 and 2004 (Canadian Fitness

and Lifestyle Research Institute, n.d.) and the Canadian Community

Health Survey (CCHS) has been completed twice since 2000 (Health

Canada, 2005). Until1998 however, the PAM did not survey the northern

territories. Because of this, there is very limited data available on Inuit PA

patterns. There is a lack of culturally relevant questions used for the two

existing surveys. For example, both surveys only measure leisure-time

PA by providing a list of activities that includes activities such as

gardening, rollerblading, and golfing. These are examples of activities that

are infrequently performed in the North due to environmental conditions. It

can be argued that these surveys fail to capture true PA patterns of Inuit

populations due to a lack of cultural relevance.

1.8 Measuring PA

It is inherently difficult to measure and to quantify daily PA

(Melanson, Freedson, & Freedson, 1996) as it is multidimensional, brief in

duration, (Tremblay, Katzmarzyk, & Wilms, 2002), and has large within

and between person variability (Freedson & Miller, 2000; Terrier, Aminian,

& Schutz, 2001). There are many different methods for assessing PA

patterns and for estimating energy expenditure, but none are considered

to be the 'gold standard' (C. E. Matthews & Freedson, 1995; Pois et aL,

1998). Sorne of these include activity diaries, questionnaires, doubly­

labelled water, heart rate monitors, pedometers, and accelerometers. Ali

of these methods have inherent limitations in accuracy and/or feasibility,

but are useful in certain circumstances (Montoye, 2000). Methods to be

used should reflect the objectives of each study, population size, and other

characteristics such as age, gender, and culture (Freedson & Miller, 2000;

Montoye, 2000; Pois et aL, 1998), as weil as cost (Melanson et aL, 1996;

Tremblay et aL, 2002). Until there is an inexpensive, accurate, and simple

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method for the assessment of PA and energy expenditure, non-ideal

methods are relied upon (Bratteby, Sandhagen, Fan, & Samuelson, 1997).

1.8.1 Objective Measures

Objective measures are the most accu rate methods of estimating

energy expenditure (Staten et aL, 2001). They are limited however to

smaller scale studies due to time requirements and cost (Staten et al.,

2001).

1.8.1.1 Doubly-Labelled Water

Doubly-Iabelled water (DLW) is the most accurate method available

to quantity daily energy expenditure and PA in free-living subjects

(Bratteby et aL, 1997). This method does not restrict or interfere with

habituai physical activities (Bratteby et aL, 1997). DLW is costly and

complicated and is therefore not feasible for large studies (Bratteby et al.,

1997). Also, the DLW method cannot detect short-term changes in PA

and energy expenditure (Bratteby et aL, 1997; Welk, Blair, Wood, Jones, &

Thompson, 2000) and therefore cannot detect patterns in PA (Bassett,

2000) or exercise intensity (Melanson et aL, 1996).

1.8.1.2 Heart Rate Monitors

Heart rate (HR) and energy expenditure are closely related

(Bassett, 2000; Rodriguez et aL, 2002) as HR and oxygen consumption

share a linear relationship at a steady-state of exercise (Bassett, 2000;

Melanson et al., 1996; Trost, 2001). HR monitors can store data to

provide estimates offrequency, intensity, and duration of PA (Trost, 2001).

The use of HR monitoring is restricted by the need to monitor undisturbed

minute-by-minute recording for at least three consecutive days (Bratteby

et aL, 1997). It is also time consuming as individual calibration is needed

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to determine the relationship between oxygen uptake and HR for each

subject (Bratteby et al., 1997; Trost, 2001).

Because HR takes some time to reflect the intensity of PA being

performed (Trost, 2001; Welk, Corbin, & Kampert, 1998), and is affected

by age, fitness level, and emotions (Bassett, 2000) as weil as mode of

exercise and body size (Trost, 2001), the accuracy of prediction is

questionable. In general, HR monitors have been observed to

overestimate energy expenditure in moderate PA and underestimate time

spent in resting/light activity (Strath, Bassett, Thompson, & Swartz, 2002)

but are found to be useful in selected study populations (Montoye, 2000).

It may not however be appropriate for assessing PA over an extended

period of time as more time is generally spent being inactive than active

on a daily basis (Welk et aL, 1998).

1.8.1.3 Pedometers

Pedometers record vertical acceleration of the body in steps. They

do not measure energy expenditure (Montoye, Kemper, Saris, &

Washburn, 1996) nor do they store data over a specified time interval from

which activity patterns can be seen (Bassett, 2000; Freedson & Miller,

2000). It is thought that pedometers lack sensitivity as they do not

quantify stride length or total body displacement (Levine, Baukol, &

Westerte rp, 2001) and detect fewer than actual steps at slow walking

speeds (Crouter, Schneider, Karabulut, & Bassett, 2003; Le Masurier &

Tudor-Locke, 2003). They cannot distinguish between walking and

running (Bassett, 2000) and are insensitive to cycling and stair c1imbing

(Trost, 2001). The main advantage to using pedometers is that they are

small in size and low in cost (Freedson & Miller, 2000). Pedometers can

be useful in walking intervention studies where a set number of steps are

the goal (Freedson & Miller, 2000). In this way, they can be used as a

motivational tool. The accuracy of the steps recorded varies among

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different brands of pedometers (Tremblay, Shepard, McKenzie, & Gedhill,

2001) and is influenced by body size and speed of movement (Trost,

2001).

1.8.1.4 Accelerometers

Accelerometers calculate the average amplitude of body

accelerations within a specifie time period (Terrier et aL, 2001) where the

acceleration of the body is directly proportional to the muscular forces

(Montoye et aL, 1996). In theory, accelerometry is the ideal tool for

temporal tracking of the frequency, intensity and duration of physical

activities (Terrier et aL, 2001) as accelerometers provide good estimations

of different PA levels and patterns (Bassett et aL, 2000; Terrier et aL,

2001; Welk et aL, 2000) and can store data for days or weeks at a time

(Hendelman et aL, 2000; Leenders, Sherman, & Nagaraja, 2000).

Accelerometers are available with one, two, or three acceleration

recording planes, with the majority having one or three. The uniaxial

accelerometer was the first, and later the additional planes were added to

capture a greater proportion of free-living activity. However, an

improvement in accuracy depends on the type and therefore direction of

movement performed (Kumahara, Tanaka, & Schutz, 2004) and the

benefits of the additional planes have not been observed unanimously.

Sorne studies have reported similar results for uniaxial and triaxial

accelerometers (Hendelman et aL, 2000; Leenders et aL, 2000; Welk et

aL, 2000; Welk & Corbin, 1995) and sorne have suggested that the triaxial

provides better estimates than the uniaxial models (Bouten, Venne,

Westerterp, Verduin, & Janssen, 1996). It seems that even the more

advanced technologies are subject to the same inherent limitations.

Both uniaxial and triaxial accelerometers have been tested for

accuracy of PA pattern and energy expenditure measurements in

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controlled environments and in the field at different speeds, intensities,

and during different types of activities. There are many contradictions in

the literature regarding which brand of accelerometers overestimate or

underestimate certain activities. The different methods used to validate

the accelerometer might be to blame for the discrepancies. For example,

when self-reports were used as the validation tool, an underestimation of

energy expenditure was reported (Leenders et al., 2000; C. E. Matthews &

Freedson, 1995); when oxygen consumption was used to validate the

accelerometers, an underestimation of energy expenditure was not

reported by (Sherman et aL, 1998), but was by Kumahara et al. (2004).

Among the conflicting results, there are a few commonalities: the accuracy

of the energy expenditure estimation is higher for walking and running

than for lifestyle activities (Bassett, 2000; Welk et aL, 2000);

accelerometers provide a more accurate measure of PA level and patterns

than prediction of energy expenditure (Bassett, 2000; Leenders et aL,

2000; C. E. Matthews & Freedson, 1995; Welk et aL, 2000); and the

regression equations used by the accelerometers to predict energy

expenditure are not likely to be accu rate for ail types of activities (C. E.

Matthews & Freedson, 1995).

Most accelerometers are designed to be worn on the hip, thus

upper body and upper limb movements are largely underestimated if

detected at ail (Strath et aL, 2002; Swartz et aL, 2000; Welk et aL, 2000).

They are also insensitive to stair climbing and cycling (Trost, 2001). The

extent to which accelerometer outputs are able to reflect changes in

incline have been tested and it was found that the increased energy

expenditure was not recorded in triaxial (Hendelman et aL, 2000; Levine et

aL, 2001) or in uniaxial accelerometers (Hendelman et al., 2000; Nichols,

Morgan, Chabot, Sallis, & Calfas, 2000). Oespite their limitations,

accelerometers are small, non-invasive, and provide objectivity. Do date,

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they are one of the best methods of PA measurement (Freedson & Miller,

2000; Schutz, Weinsier, Terrier, & Durrer, 2002; Swartz et aL, 2000).

1.8.2 Self-Reported Measures

Self-report measures are simple, inexpensive and appropriate for

large-scale studies (Leenders et aL, 2000) and are the most widely used

methods of measuring PA (Sallis & Saelens, 2000).

1.8.2.1 Activity Diariesl Activity Logbooks

Activity diaries or PA log books have been used for several decades

to measure PA (Bratteby et aL, 1997). They are inexpensive and

uncomplicated to administer and are therefore more suitable than other

methods for population studies (Bratteby et aL, 1997). Activity diaries can

represent a detailed profile of types of PA and the context in which they

were performed (Timperio, Salmon, Rosenberg, & Bull, 2004). The

accuracy of the reported data is highly dependent on the co-operation of

the participants (Bratteby et aL, 1997). It has been found that activity

diaries underestimate energy expenditure during sedentary activity and

overestimate energy expenditure during non-sedentary activities due to

high energy cost equivalents for the latter (Rodriguez et aL, 2002). Short

recording intervals should be used in activity logs because frequent

activities of short duration are habitually underestimated (Bratteby et al.,

1997; Tremblay et aL, 2002).

1.8.2.2 Questionnaires

Questionnaires are usually the most practical method to use in

large-scale epidemiological studies (Masse, 2000; Montoye et aL, 1996;

Pois et al., 1998; Richardson, Ainsworth, Bassett, & Leon, 2001) as they

are inexpensive and feasible (Montoye et aL, 1996) and are non-reactive,

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meaning they do not elicit behavioural changes of the surveyed

populations (Kriska & Caspersen, 1997). Questionnaires should measure

type, intensity, frequency, and duration of PA (Pois et aL, 1998;

Washburn, Heath, & Jackson, 2000). They should also be simple to

complete, score, and be appropriate for the population in which it is being

used (Richardson et aL, 2001). Some questionnaires are complex and

time consuming to answer; there is limited data suggesting that an

increase in complexity increases questionnaire validity (Tremblay et aL,

2002). If one decides to use a more complex questionnaire, the amount of

assistance available for the respondents during completion should be

considered (Tremblay et aL, 2002). Overestimation is very common with

self-reported PA and this can be addressed by scaling down the

overestimated records (Tremblay et aL, 2001). Published tables of energy

costs of various activities are needed to convert data obtained from

questionnaires into estimated energy expenditure.

1.8.3 Combination Methods

Each method, whether subjective or objective has many limitations.

Many researchers have combined different methods in an attempt to

compensate for these limitations. HR monitors and accelerometers have

been used simultaneously to increase the accuracy of energy expenditure

prediction of lifestyle activities (Freedson & Miller, 2000; Swartz et aL,

2000; Welk et aL, 1998). Strath et al. (2002) found an increase in energy

expenditure accuracy but the combined technique has limited application

due to its time consuming nature. Welk et al. (1998) found that the

combined methods provided no great advantage over the HR and

accelerometer alone. Different combinations of accelerometer placements

have also been used on individual subjects. In an attempt to record upper

limb movement, accelerometers have been placed on wrists as weil as

hips (Swartz et aL, 2000). It was found that the improvement in accuracy

of prediction was not justified by the additional cost, data analysis, and

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required time (Kumahara et al., 2004; Swartz et al., 2000). Self-report

methods such as PA log books can be used in combination with certain

objective measures to capture the physical activities that are overlooked

by these objective measures.

1.9 Available Questionnaires

The PA questionnaires that are being used by different government

and non-government organizations in various countries vary significantly.

Frequently, the components of the questionnaires that differ are the time

frame, complexity, type of activity surveyed, and scoring protocol (type,

duration, frequency, and intensity) (Kriska & Caspersen, 1997). Other

differences are whether the questionnaire is self or interview administered.

It is also important to note that not ail questionnaires being used have

been tested for validity and reliability.

1.9.1 The International Physical Activity Questionnaire (IPAQ)

The International Physical Activity Questionnaire (IPAQ) was

developed in 1996 by an International Consensus Group in an attempt to

address the lack of internationally comparable PA measures (IPAQ, 2005).

Two versions of the IPAQ were developed, the short and long versions.

The short version was designed to be used in surveillance studies. The

long version was designed for a more comprehensive assessment of daily

PA and to be used in research. The IPAQ assesses PA performed in

different domains including leisure time, domestic activities, work-related,

and transport-related activity and is designed to be culturally adaptable.

The reliability and validity tests of the IPAQ show that its abilities to

measure PA are comparable to other generally accepted self-report PA

methods. Correlation ranges of 0.34 to 0.89 in reliability studies and 0.14

to 0.53 in validation studies were seen (Craig et al., 2003).

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The IPAQ has been selected for use in various high profile studies

such as the European Physical Activity Surveillance System (EUPASS),

the European Health Interview Survey (EUROHIS), the Countrywide

Integrated Non-communicable Oisease Intervention (CINOI), and the

WHO World Health Survey (WHS) (IPAQ, 2005). However, the statistical

methods used to determine the reliability and validity of the IPAQ have

been criticized (Hallal & Victoro, 2004) and a study involving the

measurement of PA of urban indigenous Australians abandoned the IPAQ

when the participants had considerable problems understanding and

completing the questionnaire (Marshall, 2004).

1.9.2 The Modifiable Activity Questionnaire (MAQ)

The Modifiable Activity Questionnaire (MAQ) is designed to be

adaptable to many different populations. Past-year and past-week

occupational and leisure activities are assessed as weil as inactivity

caused by disability. It is recommended that the questionnaire be

administered via trained interviewer of the sa me race or ethnic group as

the respondents (Kriska, 2000). The MAQ was formerly known as the

Pima Indian Physical Activity Questionnaire and thus its reliability and

validity have been tested in Pima Indian men and women of various ages

(Kriska et aL, 1990).

1.9.3 The Canadian Community Health Survey (CCHS)

The Canadian Community Health Survey (CCHS) is a government

funded cross-sectional survey that collects data on health status, health

care use, and health determinants such as PA for the Canadian population

(Statistics Canada, 2005a). The CCHS is interview-administered and

focuses primarily on leisure-time PA with a time frame of the previous

three months.

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1.10 Cultural Considerations when Measuring PA

There are four general tasks that survey responders must perform:

interpretation, memory retrieval, judgment formation, and response editing

(Warnecke et al., 1997). When developing or choosing a questionnaire to

use, it is important to bear in mind the notions of emic and etic constructs:

emic constructs have culturally specifie meanings whereas etic constructs

are considered to be universally understood. Using standardized

questions to elicit information from a multicultural society may elicit a

category fallacy, that is, when emic constructs are treated as etic

constructs (Warnecke et aL, 1997).

Variability of responses might be affected by the meanings different

cultures and subgroups, age and gender for example, attach to certain

concepts (Mayer et aL, 1991). It has been suggested that providing eues

in the questions that will enhance the respondents' understandings will

help to address this problem of misinterpretation (Warnecke et aL, 1997),

and having an administrator of the sa me race or ethnicity conduct the

interviews is very important (Marshall, 2004). Also, questions must be

very specifie and unambiguous to the ethnie and cultural group being

measured (Kriska, 2000). Open-ended questions should be used with

caution as they are prone to interpretation biases (Kriska, 2000). Patterns

of response editing meant to enhance social desirability regarding health

and risk behaviour were also found to be related race and ethnicity

(Warnecke et aL, 1997). Many questionnaires solely focus on leisure-time

or recreational PA but when the study population has a large intra­

variation of occupational activity, these questionnaires would not be

appropriate (Wareham et aL, 2002). Also, the assessment of multiple

domains of PA and not only leisure-time PA is needed for an

internationally comparable PA measure (Craig et aL, 2003).

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1.11 Questionnaire Validation

1.11.1 Indirect Indicators of Physical Health and Activity

There are some anthropometric and physiologic parameters that

have been shown to be affected by PA and to reflect physical health. HR

has been related to ali-cause mortality and is considered a predictor of

physical health status (Seccareccia et aL, 2001). It has also been seen in

epidemiological studies (R H Fagard, 2005) and in meta-analyses of

randomized-controlled trials (Robert H Fagard, 2001; Whelton, Chin, Xin,

& He, 2002) that blood pressure decreases with an increase in PA. BMI

was used as an indirect physiologic measure of long term PA as BMI

should be inversely proportional to average energy expenditure (Littman et

al.,2004).

It has been seen that sedentary lifestyles are associated with a gain

of abdominal fat (Slentz et aL, 2005) and that aerobic exercise has been

shown to reduce intra-abdominal fat (Okura, Nakata, Lee, Oh kawa ra , &

Tanaka, 2005). Waist-hip circumference ratio gives a representation of

both subcutaneous and intra-abdominal adipose tissue (Gibson, 1990)

which, when measured with BMI improves the prediction of the health

burden of obesity (World Health Organization, 2000). Bioelectrical

impedance is a safe and convenient way of determining body composition

in terms of fat-free mass (Gibson, 1990).

Basal metabolic rate (BMR) can also be used as an indirect PA

reference indicator as there is a positive relationship between the two; PA

increases basal metabolism (Whitney & Rolfes, 2002).

Insulin resistance, which elicits clinical abnormalities such as

elevated glucose (Fletcher & Lamendola, 2004), is directly related to an

individual's level of PA (Seals et aL, 1984), and according to Hawley et al.

(2004), regular PA is an effective method of improving insulin action where

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insu lin resistance is present. It has been found that insu lin sensitivity can

be improved by participating in regular exercise programs of moderate and

vigorous intensities (Houmard et aL, 2004). Seals et al. (1984) have also

found that a decrease in insulin sensitivity seen with increasing age can

sometimes be prevented by participating in regular vigorous PA (Seals et

al., 1984). The homeostasis model assessment (HOMA) is a common

measure of insu lin resistance (O. R. Matthews et aL, 1985). The

Quantitative Insulin Sensitivity Check Index (QUICKI) (Katz et aL, 2000)

and the Insu lin Sensitivity Index (IS10,120) (Gutt et aL, 2000) are weil

established measures of insu lin sensitivity.

It has been seen that PA has a positive effect on blood lipid profiles

(W. Haskell, 1986). In two different meta-analysis of randomized

controlled trials, total cholesterol and triglycerides were lowered and high

density lipoprotein cholesterol was increased in participants enrolled in

aerobic exercise programs (Halbert, Silagy, Finucane, Withers, &

Hamdorf, 1999; Kelley, Kelley, & Tran, 2005).

Although the literature presents strong evidence the there are in

fact relationships between PA and health outcomes such as those

mentioned above, less is known about the particular nature of these

relationships. Currently, there are only definitive dose-response

relationships between PA and rates of certain diseases such as coronary

heart disease and type 2 diabetes (Kesaniemi et aL, 2001). The dose­

response relationships between su ch health outcomes as blood pressure,

blood lipids, and obesity have yet to be determined (Kesaniemi et al.,

2001).

1.11.2 Methods of Validating Questionnaires

One of the main limitations of PA questionnaire validation studies is

that there is no universally accepted 'gold standard' to act as validity

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instrument for questionnaires and surveys (Pois et aL, 1998; Timperio et

aL, 2004; Washburn et aL, 2000). Doubly-Iabelled water is considered

one of the best references for validating questionnaires, but only reflects

average energy expenditure over a short period of time (Montoye et aL,

1996), is expensive, time consuming, cannot distinguish between different

activities (Stel et aL, 2004) and is problematic to execute in remote

communities. Accelerometers (Tremblay et aL, 2002) and HR monitors

(Bassett, 2000) can similarly be used to validate questionnaires as they

can measure intensity, frequency, and duration as weil as energy

expenditure. Self-report methods such as logbooks and activity diaries

are other practical methods of validating PA questionnaires (Timperio et

aL, 2004).

2 Community of Focus

The current study was conducted in the community of Pangnirtung

on Baffin Island in the Canadian territory of Nunavut. The majority of the

people are Inuit with a total community population of 1200. The most

frequent language spoken is Inuktitut. Fisheries and local artists are major

contributors to the community's economy. This community was chosen in

response to the community's request for an investigation into rising obesity

and type 2 diabetes mellitus rates.

3 Specifie Goal and Objective

The main goal of this study was to evaluate the utility of PA

measurement of Inuit populations with interview-administered

questionnaires. The objective was to assess criterion validity between the

interview-administered International Physical Activity Questionnaire

(lPAQ) and the Caltrac™ accelerometer (Hemokinetics) as weil as assess

the predictive validity of the IPAQ on indirect physiologic and

anthropometric indicators of physical activity.

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4 Significance of Study

The validation of a culturally relevant PA questionnaire for Inuit

populations is important for the two main reasons. First, it is necessary to

have valid data on Inuit PA patterns that can be compared to other

national and international values, and second, it will allow for the

evaluation of public intervention programs.

5 Subjects and Methods

The aim of this study was to validate the International Physical

Activity Questionnaire (IPAQ) with the Caltrac™ accelerometer

(Hemokinetics) and with indicators of physical fitness.

5.1 Ethics Approvals and Participatory Processes

Approvals from the McGill Ethics Review Committee, the Nunavut

Research Institute, and the community were obtained (Appendix 1). The

Hamlet was involved in the development of a Community-Centre for

Indigenous People's Nutrition and Environment (CINE) research

agreement (Appendix 2) which used the participatory process developed

by the WHO and Dr. Harriet Kuhnlein from CINE (World Health

Organization and Centre for Indigenous Peoples' Nutrition and

Environment, 2003). This participatory process attempts to "balance

interests, benefits and responsibilities between the Indigenous Peoples

(IP) and the research institution (RI) concerned, through a commitment to

equitable research partnership ... the entire process, from planning to

reporting, will be transparent and accessible to ail parties involved" (World

Health Organization and Centre for Indigenous Peoples' Nutrition and

Environment, 2003). Guidance and feedback was provided by the Inuit

Tapiriit Kanatami (ITK), the Government of Nunavut Health and Social

Services Department and the Nunavut Tunngavik Incoporated. Inuktitut

translations of the consent forms (Appendices 3 and 4) and IPAQ

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(Appendix 5) were done by the members of the community steering

committee and the community research assistants. The interviews were

performed by bilingual Inuktitut community researcher assistants.

5.2 Participant Recruitment

This PA pilot project was one part of a larger community health

screening pilot project involving Inuit adults aged 18 years and over.

Three information sessions held by the community research assistants as

weil as pamphlets and radio announcements were used as recruitment

tools. Participants who volunteered for the larger health screening were

also informed about the PA validation study. Interested participants were

given a separate consent form explaining the purpose and goals of the

study, the role of the participants and researchers, the potential risks to

the participants, and the benefits that would be gained by the participants

fram the research being conducted. A signed consent form was obtained

fram each participant before the study began. Ali data were collected

during a one and a half week period in May of 2005.

5.3 Sam pie Size

The sample size of this study was determined by two main criteria:

the sample sizes used in previous PA questionnaire validation studies and

the number of available participants in the community. Previous validation

studies have reported a wide range of study participants. On the lower

end, a sample size of 35 was reported by Staten et al. (2001) for the

validation of the Arizona Activity Frequency Questionnaire, while on the

higher end, (Stel et aL, 2004) used 439 participants for the validation of

the Longitudinal Aging Study Amsterdam (LASA) Physical Activity

Questionnaire. The majority of validation studies however, have used an

intermediate sample size. For example, there were 26 population samples

taken fram twelve countries in the IPAQ validation study, and the median

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sample size was 90 (Craig et aL, 2003) and 89 participants were used for

the validation of the Sub-Saharan Africa Activity Questionnaire (Sobngwi,

Mbanya, Unwin, & Aspray, 2001). Our projected sample size was

approximately 50-60 male and female participants, but due to time and

costs constraints, we had 56 participants in total, 30 of whom wore the

Caltrac. Of these 56 participants, 12 were not included in the analysis as

they did not complete the IPAQ which left a sample size of 44. Of the 30

Caltrac participants, equipment failure and compliance problems resulted

in only 18 participants successfully completing the Caltrac monitoring for

seven days.

5.4 Component 1: IPAQ Modification

The interview-administered, short-version of the IPAQ was used in

this study. The IPAQ assesses PA performed in different domains

including leisure time, domestic activities, work-related, and transport­

related activity over the last seven days. The short version of the IPAO

includes information on the time spent walking, in vigorous and moderate

intensity activities, and in sedentary activity. It is recommended that

cultural adaptations are made to the physical activities used in the original

IPAQ questionnaire in order to increase cultural relevance (IPAQ, 2005).

The IPAQ protocol emphasizes three key concepts related to cultural

adaptation. These include conceptual equivalence, which ensures that

people atlach the same meaning to terms and concepts used; metric

equivalence, which ensures the substitute activities have the same

intensity levels as the original activities; and linguistic equivalence, which

ensures that the meanings rather than words of the questions are

translated appropriately. Nunavut Health Promotion Specialists,

Community Health Representatives, and members of the local community

were consulted during the cultural adaptation of the IPAO in this study.

These people worked together to decide on a list of culturally appropriate

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examples of physical activities to replace the original examples in the

IPAQ.

5.5 Component 2: PA Measurement

PA was measured with the IPAQ and a Caltrac activity monitor,

which is an electronic monitor that uses an accelerometer to detect

movement. The participant's basal metabolic rate is calculated by the

Caltrac by imputing age, weight, height, and gender. This monitor is worn

at hip level and is attached on the outer surface of the clothes. It is small

(about the size of a pager) and non-invasive. This type of monitor is

considered one of the best methods of PA measurement (Freedson &

Miller, 2000; Schutz et aL, 2002; Swartz et aL, 2000). The Caltrac was

used successfully in previous questionnaire validation studies (Richardson

et aL, 2001; Sobngwi et aL, 2001).

5.6 Data Collection

5.6.1 IPAQ

Each participant was asked to complete one IPAQ when they

returned the Caltrac. The IPAQ examined PA of the previous seven days,

which was the same seven days recorded by the Caltrac.

5.6.2 Caltrac Activity Monitor

Each participant was asked to wear a Caltrac activity monitor for

seven consecutive days. During the orientation period before the study

began, each participant was given explicit instructions in English and

Inuktitut on how to operate the Caltrac and was informed of the

precautions that should be taken when wearing the Caltrac. The

precautions included the types of activities that should not be performed

while wearing the Caltrac such as bathing and swimming, and how to

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properly attach the monitor to clothing. The participants were given

contact information where they were able to reach a member of our

research team if difficulties arose with the Caltrac. Also, when the

participants came to the clinic to answer other questionnaires or to have

measurements taken, they were asked if they were having any difficulties

with the Caltrac and if they were, appropriate steps were taken to solve

the problems.

5.6.3 Anthropometrie/physiologie referenee indieators of PA

Based on the available anthropometric measurements obtained

from the participants during the Pangnirtung Health Screening pilot project

as weil as drawing on the current literature, heart rate (HR), systolic blood

pressure (SBP) and diastolic blood pressure (DBP), body mass index

(BMI), waist circumference ryvC), total cholesterol (T-chol), high-density

lipoprotein cholesterol (HDL-chol), triglycerides (TG), homeostasis model

assessment of insu lin resistance (HOMA), Insulin Sensitivity Index (ISI),

and Quantitative Insulin Sensitivity Check Index (QUICKI) were used in

these analyses.

5.7 IPAQ Data Seoring

The data collected from each IPAQ provided separate scores on

walking; moderate and vigorous intensity activities, and sitting. The

overall level of activity is represented as a combined total score of walking

and the moderate and vigorous intensity activities. Metabolic equivalents

(METs), which are multiples of resting metabolic rate at a standard body

weight of 60 kilograms and were used to measure the volume of each type

of activity, which yielded a MET-minutes score. The MET-mins used in

the IPAQ are from the 2000 compendium of PA which lists MET scores

associated with over 600 activities (Ainsworth et aL, 2000).

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The IPAO was scored as both categorical and continuous scores.

The categorical scores are: low, moderate, and high and are based on

specifie criteria set by the IPAO International Consensus Group (IPAO,

2005). The low level represents the lowest level of PA and those who fall

in this category are considered 'insufficiently active'. Individuals at the

moderate level are classified as 'sufficiently active'. The individuals

meeting the requirements for the high level exceed the current pubic

health guidelines for PA in the United States and are said to be

accumulating enough activity to provide health benefits (lPAO, 2005).

5.8 IPAQ Data Entry

The IPAO scores for the Baffin community were first entered into

Windows Excel. For the vigorous, moderate, and walking questions, time

was converted from hours and minutes to minutes, and then subsequently

into MET-minutes/week.

MET values and formula for computation of MET-mins from the IPAO

protocol (IPAO, 2005) were followed and were:

Walking MET -minutes/week = 3.3*walking minutes*walking days

Moderate MET -minutes/week = 4.0*moderate-intensity activity

minutes*moderate days

Vigorous MET-minutes/week = 8.0*vigorous-intensity activity

minutes*vigorous days

The MET values used in this computation were derived trom the

IPAO Reliability Study (Craig et aL, 2003). The IPAO protocol does not

instruct that the sitting question be included in the summary score of PA

but rather separately evaluated as median values and interquartile ranges.

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5.9 IPAQ Data Cleaning

Missing Values

If respondents refused to answer or responded 'don't know' for

either the day or time variables, or if data were missing in either walking,

moderate, or vigorous days or minutes, that case was removed from the

analysis. One participant was excluded due to missing values.

Truncation of data

Following the IPAO protocol's recommendation, ail walking,

moderate, and vigorous time variables exceeding '180 minutes/week' were

truncated to be equal to '180 minutes/week' and added as a new variable

(IPAO,2005). This truncation allows for a maximum of 21 hours of activity

in each PA category to be reported in one week.

5.10 IPAQ PA Continuous Score

Two continuous scores of PA were used. One variable was the

IPAO PA MET-mins which is the metabolic equivalent of the seven day

sum of vigorous and moderate intensity activity as weil as walking. The

second score was the IPAO PA kcals which represents the seven day sum

of the calorie expenditure from vigorous and moderate intensity activity as

weil as walking obtained from the following equation: MET-min x (weight in

kilograms/60 kilograms) (IPAO, 2005). The most important difference

between these two scores is that individual body weight is a factor in the

IPAO PA kcals and is not included in the IPAO PA MET-mins.

5.11 IPAQ PA Categorical Score

The criteria used to place the participants into the low, moderate,

and high categories were as follows:

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high:

a) Vigorous-intensity activity on at least three days and

accumulating at least 1500 MET-minutes/week OR

b) seven or more days of any combination ofwalking, moderate­

intensity or vigorous intensity activities achieving a minimum of at

least 3000 MET -minutes/week.

moderate:

a) Three or more days of vigorous activity of at least 20 minutes per

dayOR

b) five or more days of moderate-intensity activity or walking of at

least 30 minutes per day OR

c) five or more days of any combination of walking, moderate­

intensity or vigorous intensity activities achieving a minimum of at

least 600 MET -min/week.

low:

a) If respondents do not meet the criteria for the other two groups.

5.12 Canadian Recommendations

ln the Canadian Population Health Initiative 2004 report on

overweight and obesity prevalence, the recommendation for eliciting

health benefits from PA is to perform greater than 60 minutes of measured

PA per day (Raine, 2004). In this study, the participants were said to meet

these Canadian recommendations if their IPAQ met one of the following

criteria:

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1. Seven or more days of walking, moderate-intensity or vigorous intensity

activity for at least 60 minutes.

2. Seven or more days of any combination of walking, moderate-intensity

or vigorous intensity activities achieving a minimum of 60 minutes/day. It

is noted that while the combined number of days may add up to seven, the

IPAO does not provide information on the days of the week, thus it is

unknown whether the different activities were actually performed on seven

different days.

5.13 IPAQ Sitting Question

As previously stated, the IPAO has one question on time spent

sitting. The IPAO sitting question is not included in the summary score of

PA. Two sitting variables were produced: IPAO Sitting kcals and IPAO

Sitting MET -mins. Sitting has a MET score of one, therefore the Sitting

MET -min/week score is equal to the number of sitting minutes multiplied

by seven days.

The IPAO Sitting kcals was then obtained using the same equation

that was used to calculate the IPAO PA kcals which is: MET-min x (weight

in kilograms/60 kilograms) (IPAO, 2005).

5.14 Caltrac Activity Monitor

The Caltrac scores of energy expenditure estimates of PA were in

kilocalories. Two separate scores were recorded from the Caltracs:

1. The number of total kilocalories used (CALS USED). This number

includes ail energy expenditure, including when the participants

were in motion and when they were sedentary (sleep). This is

possible as the Caltrac continues to record energy expenditure

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representing the participant's basal metabolism when the

participant is not performing any PA. Since the scores were

recorded by the research team when the Caltracs were returned,

this score would continue to accumulate until the Caltrac was

returned.

2. The number of kilocalories expended during PA or motion (CALS

USED ACTM). This number is solely recorded during movement.

ln order for the participants to have been deemed compliant, they

had to have worn the Caltrac for at least five of the seven days. When the

participants returned the Caltracs, they were asked how many days they

were compliant. Knowing the number of days that the Caltrac had been

worn, and having the two separate Caltrac scores of energy expenditure,

we were able to adjust each participant's total score of energy expenditure

to represent an average of seven days.

For example, if the participant had worn the Caltrac for only six

days, then the CALS USED score was simply divided by six and then

multiplied by 7. However, because the participants were not able to stop

the Caltracs trom recording, the adjustment became more complicated if

the participant had only worn the Caltrac for six days but had kept it for

eight days. Here the activity kcals would be subtracted from the total kcals

in order to get a basal kcals score. Then a seven day basal kcals score

would be found from eight days and a seven day activity kcals score would

be found from six days. The seven days basal and activity scores would

then be added together to get the total seven day kcals score. In this

example, the seven day total kcals score would have been the only

Caltrac score used that participant.

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6 Results

6.1 Participant Characteristics

There were a total of 44 participants, 12 male and 32 female (Table

1). The age ranged from 19 to 74 with a mean age of 45. The mean

IPAQ score was 2099 kcals/day and the median was 2067 kcals/day. The

mean BMI was 28.2 which falls in the overweight category (World Health

Organization, 2006), but 20 out of the 44 participants were obese, 16 were

overweight, and eight were normal weight. The mean systolic blood

pressure was 110 mm Hg and the mean diastolic blood pressure was 73

mm Hg. Regarding the participants' blood lipid profiles, the mean values

for T -chol, HLD-chol, and TG were 4.12 mmol/L, 1.15 mmol/L, and 1.07

mmol/L respectively.

6.2 Background Analyses

Ali of the dependent variables were tested for outliers in SPSS

using the 'Explore' function. Of those tested, T-chol, TG, and HR (Figures

1-3) were found to have outliers. Ali tables presented are based on

analyses without outliers. The analyses were performed with and without

the outliers. The linear regression model assumptions which are that the

residuals are normally distributed, have a constant variance, and are

independent were checked with scatter plots of the standardized residuals

versus the predicted values (Figure 4-6) and with histograms of the

studentized residuals (Figure 7-9) (Stevens, 2002). With small sample

sizes however, nonnormality is sometimes difficult to see graphically due

to sample error (Stevens, 2002), thus the Kolmogorov-Smirnov test was

also performed on the dependent variables. From this test, only the

QUICKI variable was seen to deviate from normality. Both the IPAQ PA

kcals and IPAQ PA MET-mins had similar positively skewed distributions.

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Bivariate correlations between the dependent variables show that

their relationships correspond with what is seen in the literature. For

example, WC was positively correlated with BMI (psO.01) while HDL-chol

was negatively correlated with BMI (psO.05). Also, it is normal to see

lower energy expenditure in females than males and to see a decrease in

energy expenditure with age. In this study, there were negative but not

significant correlations with both IPAO PA kcals and IPAO PA MET-mins

and age, and male participants had higher mean PA energy expenditure

than the females (1032 vs. 838 kcals/day).

6.3 IPAQ PA Analysis

There were no significant bivariate correlations between the two

IPAO PA scores and any of the dependent variables (Table 2). Two sets

of linear regressions were performed for each dependent variable.

Because we had 44 participants in total, we adjusted for three dependent

variables in the first set of regressions (age, gender, and waist

circumference) when evaluating the primary dependent variable of

interest. In the second set of analyses, men were excluded which left 32

participants and analyses adjusted for age and waist circumference. Both

IPAO PA kcals (psO.05) and IPAO PA MET-mins (psO.05) variables were

significantly inversely related to BMI when men were excluded and the

regression model was adjusted for age and waist circumference (Table 3).

Also, the IPAO PA MET-mins was a significant predictor (psO.05) and

IPAO PA kcals was a borderline significant predictor (p=0.06) of HDL-chol

when the men were excluded in analyses adjusting for age and waist

circumference (Table 3).

6.4 IPAQ Sitting Question

The median sitting energy expenditure was 2552 calories/week.

The interquartile range was 2325 calories/week. There was a significant

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inverse correlation between the IPAO Sitting kcals and HOL-chol (r = -

0.37, p.:s.0.01) and positive correlations between the IPAO Sitting kcals and

SMI (r = 0.43, p.:s.0.01), and WC (r = 0.44, p.:s.0.01) (Table 4). However,

partial correlations between IPAO Sitting kcals and the anthropometric

measures while controlling for body weight were not significant (Table 4).

Also, IPAO Sitting kcals was not a significant predictor of any dependent

variable in the multivariable linear regressions (Table 5).

6.5 IPAQ vs. Canadian Recommendations

Thirty-one out of the 44 participants met the Canadian

recommendations for PA (Table 6). Ali of the 24 participants in the high

active group and seven of the moderate active participants made up the

group who met the Canadian recommendations. None of the participants

who were placed in the low category met the Canadian recommendations.

Five out of the 12 participants who were labelled as moderately active by

IPAO standards, did not meet the requirements to be considered

sufficiently active by Canadian standards.

6.6 Caltrac

There were a number of problems implementing the Caltrac in the

community, which resulted in too few Caltrac scores available for

analyses. Thirty Caltracs were given out in total, but only 18 participants

successfully completed the trial and 15 of the 18 were women.

Although the study population showed great interest in wearing the

Caltracs, many compliance problems arose during the study. These

problems were less attributed to the participants' willingness to adhere to

the requirements, and more to functional factors associated with the

design of the Caltrac and to the physical environment. Attempts were

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made throughout the study to rectify the problems, but most could not be

corrected.

Twice, the pin used to attach the clip to the rest of the Caltrac was

jiggled loose, separating the clip from the Caltrac, which caused the

Caltrac to fall off the participants. This happened while shovelling snow

and playing volleyball. Two other participants said that the clip was too

loose which caused the Caltrac to repeatedly fall off when walking. These

participants reported that when the Caltrac would hit the floor, the

numbers would reset. There were a few incidents where participants

removed the batteries at night when they took off the Caltracs. After these

incidents, a piece of tape was placed over the batteries before the

Caltracs were handed out. Also, because of the cold temperatures, one

participant's batteries died within three days of wearing the Caltrac.

Sorne participants wore the Caltrac for fewer than the required

seven days and sorne kept the Caltrac for longer than the seven days.

This usually happened when the participants left town during the seven

day monitoring period; they either returned the Caltrac before they left

which would mean they were monitored for fewer than seven days, or kept

the Caltrac until they returned to the community which meant it was

recording data for longer th an seven days. The study team also noticed

that many of the participants wore pants with elastic waistbands which

made it difficult to keep the Caltracs in proper position on the body. Two

participants were seen wearing their Caltracs in the front pockets of their

pants which does not allow for proper PA recording.

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7 Discussion

Over 75 percent of the participants were either obese or

overweight. The IPAQ PA kcals and MET-mins were able to predict BMI

and HDL-chol in multivariate regressions but were not significantly

correlated with any other anthropometric or physiologic measures.

Although the literature is inconclusive, there is evidence to suggest

that the effect of PA on blood lipids is dependent on the intensity of

activity. In one meta-analysis of randomized controlled trials, it was

reported that T -chol was affected more by higher intensity exercise

programs and TG and HDL-chol were more affected by lower intensity

exercise programs (Halbert et aL, 1999). There are currently no concrete

dose-response data available for exercise and blood lipids, but a

'threshold' may exist before changes in lipids occur (Halbert et aL, 1999).

It is unclear if this 'threshold' is related to volume of exercise or baseline

lipid concentrations 0fV. L. Haskell, 1986) as it appears that nonstructured

lifestyle activities do not affect blood lipids (Leon & Sanchez, 2001) and

that the higher the lipid concentrations prior to exercise programs the

greater the reduction (W. L. Haskell, 1986). To address the issue of

exercise volume, linear regressions were performed for T-chol, HDL-chol,

and TG once again, but this time the IPAQ outcome variable was the

caloric energy expenditure of vigorous activity only in both kcals and MET­

mins. No significant relationships were found with vigorous activity and

the blood lipids, but this is not entirely surprising considering that only 12

participants performed vigorous activity in the community pilot study.

There are currently no available data on thresholds that can be

used with which to compare the IPAQ Sitting scores (IPAO, 2005). The

IPAQ Sitting kcals score was significantly correlated with BMI, HDL-chol,

and WC. These relationships are consistent with the evidence that

physical inactivity has a negative impact on health status. It is interesting

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to note that the IPAO Sitting kcals score has stronger correlations with

SMI and HDL-chol than the IPAO PA kcals score. One reason for this

trend may be that it could be easier to recall time spent sitting than it is to

remember time spent in different physical activities. In this way, sitting,

which is an inverse proxy of PA, may be a useful indicator of health risks.

As previously stated, the important difference between the MET­

mins and kcals scores in both IPAO PA and IPAO Sitting is that body

weight is a factor when kcals are calculated but not a factor in the formula

used to calculate MET-mins. The fact that the IPAO Sitting MET-mins

score was not correlated with any of the dependent variables suggests

that it is the effect of body weight and not the actual energy expenditure of

sitting that is producing the results seen with the IPAO Sitting kcals score.

Furthermore, there were no significant partial correlations between the

IPAO Sitting kcals score and HDL-chol and SMI when controlling for body

weight.

It is clear that the two extreme IPAO categorical scores, high and

low, parallel the criteria used to determine if the Canadian

recommendations have been met as none of the participants who were

placed in the low category and ail of those in the high active group met the

Canadian recommendations. There is sorne disagreement with the

moderately active group; by IPAO standards, moderately active is

sufficiently active, but in this study, five out of the 12 participants who were

labelled as moderately active by IPAO standards did not meet the

requirements to be considered sufficiently active by Canadian standards.

Overreporting of PA has been seen with the IPAO in the past

(Rzewnicki, Auweele, & Sourdeauhuij, 2003) and the means and medians

of reported PA by the IPAO have been higher than public health

recommendations in sorne European countries (Rutten et aL, 2003). One

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argument for this observation is that the IPAQ incorporates a wide range

of activity domains whereas many other questionnaires focus only on

leisure-time PA (Rzewnicki et aL, 2003). This pattern is seen in the

current study as, according to the IPAQ scores, over 70 percent of the

participants met the Canadian recommendation for PA which is an

accumulation of at least 60 minutes of measured activity per day. This is

much different than what was reported by the CCHS 2003 which was that

only 24 percent of Canadians met this sa me level of activity but only

measured leisure-time PA (Statistics Canada, 2005b).

Originally, as suggested by the IPAQ International Committee, we

had planned to use the IPAQ long version as it was designed for a more

comprehensive assessment of daily PA and suitable for use in health

research (IPAQ, 2005). When the Nunavut Health Promotion Specialists,

Community Health Representatives, and Community Steering Committee

were consulted, it was unanimous that the long version would be too

demanding on the participants to complete and suggested that the short

version be used. Using the short version was a compromise in regards to

the amount of detail we were able to obtain from the IPAQ, but if the long

version would have been used, it is likely that fewer participants would

have agreed to complete the questionnaire.

The feedback from the interviewers was that many of the

participants found it very difficult to recall the specifie number of days and

length of time they had spent being physically active. This was reflected in

the data as many of the participants reported inconceivably high levels of

activity. Very similar to what Rzewnicki et al. (2003) reported, the bilingual

Inuktitut community research assistants also had difficulty explaining to the

participants the differences between the intensities of PA. Specifically,

differentiating between what activities were to be considered 'moderate­

intensity activities' and those that were to be recorded as 'walking'. This

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was due to the many 'moderate-intensity' activities that are performed

while walking, such as carrying light loads and children, thus, there was

overlap between these two categories. One of the interviewers suggested

that to avoid confusion, the order of the IPAO items should be re-arranged

so that the 'walking' question would be first.

This study is limited due to the low number of participants and the

homogeneity of the sample: 73 percent were women and 43 percent of the

participants were 50 years and older.

The study results show that the IPAO has potential. However, it

needs further refinements to be acceptable to Inuit and needs re­

evaluation in a larger sample.

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8 Conclusion and Summary

When this project was being developed, the Caltrac was intended

to be used as the primary IPAO validation tool. However, with sa many

Caltrac technical mishaps, the data set was tao small to evaluate the

validity of the IPAO against an objective measurement of activity. Similar

technical difficulties with the Caltrac were observed in a questionnaire

validation study in the Pi ma Indians (Kriska et aL, 1990). Secause the

Caltracs did not perform as anticipated, the focus was placed on the

participants' anthropometric and physiologic measurements which are

known to correlate with physical activity as a means of validating the

IPAO. From these analyses, it was found that the IPAO PA kcals and

MET-mins scores were significant predictors of HDL-chol and SMI in

multivariate regression analyses. The IPAO Sitting kcals score was

significantly correlated with HDL-chol and SMI. The results from the IPAO

Sitting kcals score must be interpreted with caution, however, as the

evidence points to body weight, and not energy expenditure of sitting, as

the true predictor of HDL-chol, SMI, and WC.

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9 Future Recommendations

If there would have been enough Caltrac scores to analyze, it would

have been very useful to have an output score from the Caltrac that was

not obtained by using body weight. In the future, choosing an objective

PA measure that produces energy expenditure scores as both calories

and a score such as number of steps or distance traveled should be

considered. This would have been useful as body weight heavily

influences how many calories the Caltrac reports for each participant.

Choosing an accelerometer or pedometer that is more sturdy and hearty

than the Caltrac would also be advised. There were many problems with

pieces of the Caltrac breaking and the Caltrac itself falling off of the

participants. Also, it might be of interest to choose a monitor that has a

case or cover which makes it more difficult for the participants to change

the settings and remove the batteries.

ln regards to the IPAQ, we did not spend enough time training the

interviewers on how to ask the questions properly and to answer the

participants' questions in the most appropriate ways. We assumed that

administering the questionnaire was simpler than it actually was for

participants. From the feedback from the interviewers, it was obvious that

there were serious misconceptions and misunderstandings of the

definitions of the different PA intensities. When training the interviewers,

we should have spent more time on the interpretations of these definitions.

ln the future, proper and thorough interview training and immediate follow­

up with participants would likely increase the accuracy of the responses as

weil as lessen the participant burden caused by the misunderstanding and

frustration that is attached to retroactive recall.

Future work should assess whether time spent sitting is a useful

indicator of health risks. In this study, participants had an easier time

43

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remembering how long they had spent sitting each day than remembering

different intensities of daily PA.

44

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32(9), S489-S497.

Welk, G. J., & Corbin, C. B. (1995). The valdity of the Tritrac-R3D activity

monitor for the assessment of physical activity in children.

Research Quarterly for Exercise and Sport, 66(3),202-209.

Welk, G. J., Corbin, C. 8., & Kampert, J. 8. (1998). The validity of the

Tritrac-R3D activity monitor for the assessment of physical activity:

56

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Il. temporal relationships among objective assessments. Research

Quarterly for Exercise and Sport, 69(4),395-399.

Whelton, S. P., Chin, A., Xin, X., & He, J. (2002). Effect of aerobic

exercise on blood pressure: a meta-analysis of randomized,

contralled trials. Annals of InternaI Medicine, 136(7),493-503.

Whitney, E. N., & Rolfes, S. R. (2002). Understanding Nutrition. In (9th

ed., pp. 284). Belmont, CA: Wadsworth.

World Health Assembly 57.17. (2004). Global strategy on diet and physical

activity. Geneva: World Health Organization.

World Health Organization. (2000). Obesity: preventing and managing the

global epidemic - Report of a WHO Consultation on Obesity.

Geneva: WHO.

World Health Organization. (2006). Obesity and Overweight. Retrieved

November 7,2005, fram

http://www.who.intldietphysicalactivity/publications/facts/obesity/enl

World Health Organization and Centre for Indigenous Peoples' Nutrition

and Environment. (2003). Indigenous peoples and participatory

health research. Geneva: WHO.

World Health Organization/Food and Agriculture Organization. (2002).

Diet, Nutrition and the Prevention of Chronic Disease: Report of a

joint WHO/FAO Expert Consultation (No. 916).

Wu, T.-Y., Ronis, D. L., Pender, N., & Jwo, J.-I. (2002). Development of

questionnaires to measure physical activity cognitions among

Taiwanese adolescents. Preventive Medicine, 35(1), 54-64.

Young, T. K., & Sevenhuysen, G. (1989). Obesity in northern Canadian

Indians: patterns, determinants, and consequences. American

Journa/ of Clinica/ Nutrition, 49(5), 786-793.

Young, T. K., Shrarer, C. D., Shubnikoff, E. V., Szathmary, E. J., & Nikitin,

Y. P. (1992). Prevalence of diagnosed diabetes in circumpolar

indigenous populations. International Journal of Epidemi%gy,

21(4), 730-736.

57

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Tables Table 1. Gender and age distribution of participants (N=44).

Age Women (N = 32) Men (N = 12)

18-29 7 2

30-39 7 3

40-49 4 4

50-59 11 1

60-74 5 2

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\JI \0

Table 2. Pearson correlation coefficients of IPAQ PA scores and anthropometrics (N=44).

IPAQ PA kcals

High density lipoprotein cholesterol (mmoI/L) 0.115

Triglycerides (mmoI/L) 0.011

Body Mass Index (kg/m2) 0.054

Heart rate (bpm) 0.035

Diastolic blood pressure (mm Hg) 0.162

Systolic blood pressure (mm Hg) -0.094

Waist circumference (cm) 0.101 Homeostasis model assessment insulin resistance1 (units) -0.090 Insulin sensitivity index2 (min-' ~ mU/ITI!L_~ ~ .. _ ~.188 _ _

*Statistically significant at p<0.05. **Statistically significant at p<0.01. 1Homeostasis model assessment insulin resistance=insulin/22.5e-lnglucose)

IPAQ PA MET -mins

0.243

-0.155

-0.124

0.024

0.068

-0.144

-0.077

-0.198 0.297

21nsulin sensitivity index=body weight kilograms/mean plasma glucosellog of mean serum insulin

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Table 3. Beta coefficients and standard errors (SE) from linear regressions of IPAQ physical activity scores

predicting anthropometrics.

HDL-chol BMI ISI HR (mmol/L) (kg/m2

) (min-1 per (bpm) mU/mi)

Beta SE Beta SE Beta SE Phïsical Activitv Measure IPAQ PA kcals {~er 11000 kcals)

Women Only1 0.025 (0.013) -0.151 (0.074)* 2.509 (2.234) -0.060 (0.310) Women and Men2 0.017 (0.01) -0.061 (0.057) 2.728 (1.773) -0.058 (0.226)

IPAQ PA MET-mins {~er 11000 MET-mins)

Women Only1 0.036(0.016)* -0.192 (0.094)* 3.423 (2.825) -0.053 (0.392)

Women and Men2

Adjusted for age and waist circumference. Adjusted for age, waist circumference, and gender. *Si nificant at :s0.05

High density lipoprotein cholesterol 4Sody Mass Index 51nsulin sensitivity index=body weight kilograms/mean plasma glucose/log of mean serum insulin 6Heart rate 7Triglycerides

0\ o

TG (mmol/L)

Beta SE

-0.007 (0.021) -0.009 (0.078)

-0.011 (0.026)

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0'\ ......

Table 4. Pearson and partial correlation coefficients of IPAQ Sitting scores and dependent variables (N=44).

High density lipoprotein cholesterol (mmoIlL)

Triglycerides (mmol/L)

Body Mass Index (kg/m2)

Heart rate (bpm)

Diastolic blood pressure (mm Hg)

Systolic blood pressure (mm Hg)

Waist circumference (cm) Homeostasis model assessment insulin resistance2 (units) Insulin sensitivity index3 (min-' per mU/mI)

*Statistically significant at p<0.05 **Statistically significant at p<0.01 1Controlled for body weight (kg)

Pearson correlation Partial correlation coefficients coefficients 1

IPAQ Sitting IPAQ Sitting IPAQ Sitting kcals kcals MET-mins

-0.371* -0.230 -0.169

0.059 -0.012 -0.068

0.429** 0.208 0.202

-0.042 -0.064 0.089

0.045 0.004 0.032

0.112 0.100 -0.097

0.443** 0.235 0.162

0.201 0.034 0.052

-0.155 -0.033 0.010

2Homeostasis model assessment insulin resistance=insulin/22.5e-lngIUcose) 31nsulin resistance index=body weight kilograms/mean plasma glucosellog of mean serum insulin

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Table 5. Beta coefficients and standard errors (SE) from linear regressions of IPAQ Sitting scores predicting

anthropometrics.

HDL-chol BMI ISI HR (mmol/L) (kg/m2

) (min-1 per (bpm) mU/mi)

Beta SE Beta SE Beta SE Beta SE Ph3lsical Activitv Measure IPAQ Sitting kcals {~er 11000 kcals)

Women Only1 -0.053 (0.047) 0.094 (0.202) 2.918 (8.196) 0.126 (1.099) Women and Men2 -0.064 (0.040) 0.043 (0.231) -1.143 (7.257) -0.292 (0.911)

IPAQ Sitting MET -mins {~er 11000 MET-mins}

Women Only1 Women and Men2

Adjusted for age and waist circumference. Adjusted for age, waist circumference, and gender. *Si nificant at pSO.05 High density lipoprotein cholesterol

4Sody Mass Index 51nsulin sensitivity index=body weight kilograms/mean plasma glucose/log of mean serum insu lin 6Heart rate 7Triglycerides

0\ IV

TG (mmoIlL)

Beta SE

-0.054 (0.074) -0.022 (0.064)

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Table 6. Female and male participants who met Canadian PA

recommendations and those who did not, divided by IPAQ

categorical scores of high, moderate, and low.

Met Canadian PA Did not meet Canadian Recommendations PA Recommendations

Female IPAQ Activity Level

high 17 0 moderate 6 4

low 0 6

Male

IPAQ Activity Level high 7 0

moderate 1 1 low 0 2

Total 31 13 % of total N 70.5 29.5

63

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Figures

7- 18 8

--6-

5-

--

4- --r-

3-

2-

1 Total cholesterol

Figure 1. Box-plot showing total cholesterol outliers.

4 - 18

*

3 - 10 0

--2 -

:

-

1 o -

1 Triglycerides

Figure 2. Box-plot showing triglyceride outliers.

64

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90

80

70

60

50

29 o

Heart Rate

Figure 3. Box-plot showing heart rate outliers.

3.00000-

'0 0 "-CP .. II) CP '0 2.00000-.t::

0 0 U

1

..J 0 C 0 ::I: 1.00000- 0 0 0 .... 0 0 0 II) 0 0 ni 0

o 0 ::l 0,... '0 0.00000 " Oc;; 0-. v CP

00 <li>

0:: 0 @ '0 CP 0 0 N -1.00000- 0 00 .. 0 0 0 o 0 c 0 0 CP 0 '0 ::l .. en -2.00000 -

1 1 1 1

0

1 -2.00000 -1.00000 0.00000 1.00000 2.00000

Standardized Predicted Values of HDl-cholesterol

Figure 4. Scatter plot of HDL-cholesterol studentized residuals

versus HDL-cholesterol standardized predicted values.

65

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il m .... 0 ln

Cü ::;, '0 'u; CI)

0:: '0 CI) N

:0: c: CI) '0 ::;, .. en

4.00000-

2.00000-

0.00000

-2.00000 -

-4.00000 -

1 -4.00000

cJ) 0

0

1 -2.00000

0

0 0

8 0 ~O

'è 0

o 0 0a o 0

0

0 8 0

v

00

0q,

1 0.00000

0 0

-0

0

0 0

0

1 2.00000

Standardized Predicted Values of SMI

1 4.00000

Figure 5. Scatter plot of BMI studentized residuals versus BMI

standardized predicted values.

Ci) .... 0 ln

Cü ::;, '0 'u; CI)

0:: '0 CI) N =c c: CI) '0 ::;, .. en

3.00000-

2.00000-

1.00000-

0.00000

-1.00000 -

-2.00000 -

1 -2.00000

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0

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-"'.

<>0 0 0

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00

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0

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0

ct>

0 0

o

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1.00000

o

v

o

Standardized Predicted Values of ISI

o

o o

1

2.00000

Figure 6. Scatter plot of 151 studentized residuals versus 151

standardized predicted values.

66

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-2.00000 -1.00000 0.00000 1.00000 2.00000

Studentized Residuals of till-cholesterol

3.00000

Mean = -0.0061714 Std. Dev. = 1.01754135 N=42

Figure 7. Histogram of HDL-cholesterol studentized residuals.

-3.00000 -2.00000 -1.00000 0.00000 1.00000 2.00000 3.00000

Studentized Res iduals of BMI

Mean = -0.0049311 Std. Dev. = 1.00953932 N =44

Figure 8. Histogram of BMI studentized residuals.

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>­(,) c CI) ::::J

12

10

8

CT 6 e u.

4

2

-2.00000 -1 .00000 0.00000 1.00000 2.00000

Studentized Residuals of 151

3.00000

Mean = -0.0035743 Std. Dev. = 1.00845073 N =40

Figure 9. Histogram of 151 studentized residuals.

68

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APPENDICES

69

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Appendix 1: McGili University ethics certificate

70

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MCGlll UNIVERSITY FACUl TY OF AGRICUl TURAl AND ENVIRONMENTAl SCIENCES

CERTIFICATE OF ETHICAl ACCEPTABILITY FOR RESEARCH INVOlVING HUMANS

Approval periOd:JwusR'( ~él,oJ - ~<.U).lo.R-'f ,11,05' RES #: __ 'i>~~,;",.1--,--_-,.,.Q,-,I:--=O=-~-,,-____ _

The Faculty of Agricultural and Environmental Sciences Ethics Review Committee consists of 4 members nominated by the Faculty of Agricultural and Environmental Sciences Nominating Committee and elecled by Faculty, an appointed memberfrom the community and an individual versed in ethical issues.

The undersigned considered the application for certification of the ethical acceptability of the project entitled:

Co-Applicant's Name: SUSAN 61RD

Co-Applicant's Signature ~~

Co-Applicant's Name: D Q,."leea Wty)CY't!t

Co-Applicant's Signaturt<c~41 &e~0flf'N<"

( as proposed by:

Applicant's Name GLlI/LtllNk Ctt8fBDNNEfiU Supervisor's Name (JRfJ t~ H. [{iEUWD

App'Ica",', Sig""'""' 4[.,;61& (}(,.,hBlJll(lZiA S"p .......... Sig,,,"", ~ ,41 f"'/ Degree 1 Program 1 Course Hrc tAros -nufz1flCtl, Granting Agency Oes) fa nadlqn 121q,AE7Ff Aw>mt7101

Grant TItle(s}: The emefJNlce tJf ges+aHonal (ilabd:v) "'-tl/dus. anrX drabtl.flme/kfus tllJ1fJnj 'ffle /f1I,uf ff/ rAe .6afi?n

The application is considered to be:

A Full Review / An Ex~dired!Review __

A Departmental Level Review ..,...,...--,.-+'-\~t-.' tL,.,.......,....,..,,--,.-,------­Signature of chair 1 Designate

Peter Jones Chair, Faculty of Agricultural and Environmental Sciences Ethics Review Committee School of Dietetics and Human Nutrition Tel: (514) 398-7547; F,aXi' (014) 398-7739 .fI ! i

Signature 1 date

il 1.

fÎl i

! i (lil/J .JCL("I· d Q. è)ûC4 . c..c. . E G--\o..(\6 ; L \-{c~qJl

Las! update March 2003

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MCGILL UNIVERSITY FACULTY OF AGRICULTURAL AND ENVIRONMENTAL SCIENCES REB

ETHICS REVIEW RENEWAL REQUESTIFINAL REPORT

Continuing review of human subjects research requires, at a minimum, the submission of an annual slatus report 10 the REB. This form must be completed to request renewal of ethics approval or to close a projecl file once the research has been completed or tenninated. In order to keep the REB records current, and 10 avoid any delays in the release of funds. please complete t.he following and retum it at leasl 1 month before the current approval expires.

REB#: 827-0104

Projett Title: The emergence of gestational diabetes mellilus and Iype 2 diabetes mellitus among the Inuit of the Baffm Region. Principallnvestigator: Grace M. Egeland, Ph.D. and T.Kue Young, M.D. DepartmentIPhone/Email: SDHN/398-8642/[email protected] Faculty Supervisor «(or student PI): not applicable

1. Were there any significant changes made to this research project that have any ethical implications? _ Yes _x_No If yes, describe these changes and append any relevant documents that have been revised.

2. Are there any ethical concems that arose during the course of this research? _ Yes _x_ No If yeso please describe

3. Have any subjects experienced any adverse events in connection with this research project" If yes, please describe.

4. _x_ This is a request for renewal of ethics approval.

5. __ This project is no longer active and elhics approval is no longer required.

Yes x No

6. Vou must list ail CUITent funding sources for this project and their exact titles. Indicate the Principal InveslIgator orthe award if not yOUTself.

Inuit Tapirrit Kanatami ($40,000) and Max Bell Foundation are Funding the Initial Phase of the Projec!. The Max Bell Foundation component represents $15,000 of the $240,000 awarded under the title of "Improving the Health and Health

g::a~;{Vlces in Aboriginal communitt:~oss Norte c;a/(PIIS Grace M Egeland and co-PI is Katherine Gray-

Principal Investigator Signature: ~.f<:.C -11 &Ic-L Date ~j, .2 J; 2 a~-1

Co-Principal Investigator Signature: _______________ Date: _____ _

Faculty Supervisor Signature: ________________ Date: ___ _ (for student PI)

Submit to the Faculty of Agricultural&Environmental Sciences RES, cio Lynn Murphy, Macdonald Campus Research Office, rm MS2-082; fax:5I4-398-8732

(version Jan05)

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03/02/2085 14:45

03/82/2e95 e~:51

416'3466055

e514-398-162fJ

l ~DP -K. VCl..-"lG

CINE MCGILl.

MCGILL UNIVERSITY FACULTV OF AGRlCuLTURALAND ENVIRONMENTAL SCIENCES RES

1

EllUCSREVŒW UNEWAL REQUEST/llTNAl. JlEPO'R.T

PAGE !'lZ/02

PAGE 82

Com:ùllrirls review ofhuman subjects researdl requiTu, st .. minimum, the sub.miS&ion of an anlllll1 $tahIS report to tIIe RiB. lbII tbrm mu5t 110 COn1pleted. ta RqVe$t reMWal of etbi~ approval or to elolt a proj&Çl tile once the mearch ha beeD çompI01cd or ~nated. Jn order ~ koep the REB !'CçQrd$ CUITent, and to avoid &I1Y del~ in the relll!e of Cunds. pJase complJlte ~ fuUowmg lnd tetunllt ai Il!a$t 1 IItORth bcfore dK: ~t apptQVÙ expires.

UlM: m..ot04 ProJect TItIe: The aJlergençe of plltional diabtta mel1it1ls and type 2 diabetcs meUltus among the Inuit of the Baffm RlSfan. PrIa_ bvestlptor: Gnet M. B~d. Pb.O. IIl\d T.Kue YollllBo M.D. DepartJUDtlPhoaeJEmlll: [email protected] faea,*, Sapwvitor (for f1l1deat Pl): nOl applicabll

1. Wta Ibere en)' aiBf\ifiQnt chaoS" made to th;. rtSeardl projcct tIIal ~vc lIl\y ethical impliçatjOllS? _y es _~NQ If )'tI, describe the .. changes and sppend I.lIY releV&llf documen~ d1&t bave been revised.

;1. Are tIlerc 8IIy ethical eoncems that U'0ge during lfIe course ofdûs relearch'? _ Y., _x_ No. lfyes. pleuc deseribe.

3. HavI: lIn)I.ubjectR experieneed any adverse events in connection witl1 this retC#Ch projc«1 _ y~ • .f'.~ No Tf )'81. pJease deseribe.

4.. J_ This It. requut for renewal ofc:dtlc.s approval.

s. _ This projtâ ia ''0 IOn&e&' active II1d cttriCS 8pproval is no langer reqUired.

6. YO\J must list all cummt flmdia.& IO~ for tI!.i& projcçt and their ~ titles. In4icaœ Ihe Ptincipa' ln'le$tiptor of tbe .ward ihot )'Oul"&Cif.

CooPrlacipal J.vK~tor Slglllwre:

F'acu!tySupervtsorSipat1lrel ________ - ___ Date:. ____ _ (fat IlUdeot Pl)

Submlt.., tbe Faeult,r of Agricultur::a16:tnironlZlelital SeleDces REa. eJo Lynll Murpny. Macdonald Camp1l8 R_RI! Ofr'cte, l'RI MS2-03:l; ru:Sl40398-873l

(vusfan JanOS)

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For Administrative Use REB: V AGR _EDU

__ The c10sing report of this terminated project has been reviewed and accepted

~ The continuing review for this project has be n reviewed and approved

~ Expedited Review

Signature of REB Chair or designate: ---f-H-II--""'.L------- Date:

Approval Period: JAN .2.;1, .2a:6

REB-I REB-I1

Submit to the Faculty of Agricultural&Environmental Sciences REB, cIo Lynn Murphy, Macdonald Campus Research Office, rm MS2-082; fax:S14-398-8732

(verSiOn Jan05)

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Daneen,

As per my telephone conversation with Sandra Gibon, Thesis Coordinator, Graduate and Postdoctoral Studies office, for the purpose of thesis submission it is acceptable that the title on the Certificate of Ethical Acceptability for Research Involving Human not be exactly the same as your Masters project title, provided the subject matters are similar. The certificate as you have it is acceptable.

If you have any problems, you can simply refer them to me.

Lynn Murphy Administrative Coordinator Macdonald Campus Research Office McGill University Faculty of Agricultural and Environmental Sciences 21 111 Lakeshore Road St-Anne-de-Bellevue, QC CANADA H9X 3V9 Tel: 514 398-8716 Fax: 514 398-8732

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Appendix 2: Nunavut Community-CINE research agreement

71

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HamIer of pugairtwtt He&1th SmeuJaaod Research A:reement M., 2005

The CeJitte for Jndi.senoua PcopJ.esl Nutrition and Enviromnent (CINE) agrees to oonduÇt the fOllowing activitics with the guidance and leadetship ortho Pangninung eommUDity.

1. The ovenJlgoals of the eurreat actMties ad Curue plans are:

• to dcvelop an undcntanding of what factors are contributina 10 diabctes and pœ­diabetcs amona the llmit;

• to help identify cu1turally appropriate prevention strategies and messages; and to

• pl'QIllotc hcalth through the promotion ofrnditional food and healdJy market: food.

Z. The Ma)- 2005 activiUes fadude:

• a-hcaltb. screcmiDa of adults ov« 18 Yeart of asc;

• an evaluation of a ph)'lrical aetivity questioanaire; and

• înteMews widl iDdividnals living wilh diabetes ft> Jeam about how ta improve dietaty advice.

1bc woâ: bas cthics approval from McGiU University and a Nunawt R.eseatCh License ('#OSOOSOSR-M).

3. COmlJlIwty and CINE PartnmJdp

Community input. advi~ and leadership ia providcd by the comurunity stcering committcc. T'l1e Pangoimmg Health Screening Stccring CoInmtttcc mcmbet$ incJuc1o: Donna. Ki1ab~ 10nab Xilabuk. Johnny Knluguqtuq, and Markus Wndœ.

Community interviewers, Susa Qappik and Jo10 (petet Taylor) Aningmiuq. bave bcen b.tml for the m.onth of May. They will recruit participants, explain the scteeDÎll8 and conduct interviews.

4. CommGDlty Bealtb ScreeD1ng (May ZOOS).

The health screening focuses on diabctcs. pre.diabetC$ and heart discase tbrough ~ of blood tests, bJood pressure. medica1 bistory. diet, physical activity. and bodyweight for beight and petCent body fat.

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The health scrccning rcsulta Will;

• mise awarcneas of on.es own healtb statua and health habits to he1p prevent future hœlth problems from occutth1g;

• raisc community awarencss 10 help gui~ development of hea1th promotion efforts;

• holp evaluate the 1àcton that are related. 10 the development of pxe-dîabetes and diabetet amolli the Inuit

ln addition, as there la an mterett in a f011ow-up health assessmem. the oum:m health sc.roc:ninl CID. aetVe as a baselinc lSSCSSltI.eIlt upon whicb ta compare a secon4 future asscssme.ot to hc1p detcrmine wbether hea1th promotion efforts are auçoessful (peIldjns tbat fandiDg).

50 Scope of BcrteDlD.g:

The bealth screeniDg does Ilot address cancer ti!k or othcr healt11 problems lUCh as arthrltis or boue loas.

6. ~itment Aetivklest

• Communitymembers will be asked 10 participate and participation is voluntary. • A brocbure wiU be mailcd 10 each bouseho14; • Community meetings at ANtic CoUego and radio announcemcnts will hU"onn the

commuoity orthe project; • AU particlpan.ta will sigu. a consent fotm.

The health screeniDg will take place al Arotic Collego atartins May 16th and encl by May 2"'. 'Ihc attached consent forros proYide d.etails of what eadl panicipant is expected to do.

7. W~atioD conec:te4 ia to be 1Itared, diatrlb,,-ft(!, aad Itortd bl these agreed ways:

'Ihc data co11ectcd is cozmdential. Interviewers have signed Il confideDtiality ~cnt. Once TCSUlœ are retumed 10 each participant, namcs and bbtbdate$ wiU he rcmoved ÛOUl the database that will he usecl for summary reports. lnfonnation tbat is co&ctcd v.il1 bc bpt al ClNB. A final MpOrt will bc distributed 10 tqional. tcnir~ and national Inuit organ;zatJons after approval ft'Om the community stccring com:nûttec.

Any d.ocument. such as a conference presentation or a publication, will he sbared with the community steering committee for their review. No document or presentation will he

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made Without the written tppt'Oval orthe community $teeDng committoe. The ÇQlJ)tmU1ity Dame win or win DOt be used in any presernation depeading upon the wishea of tbe community stecring committec.

8. ProJeet p~ will he eamllMlllleatecl to the eommUllit)' ta. th_ agreed ways:

Bach individual will n:ccive thcir own penonal reau1ts witbin 60 d8)'I of the completion orthe data ~ A visit to thb (ommunity in the faU of 2005 ,. planned te provide summary data of the rcsuhs back. to the oommunity.

9. ()unJDuJdcatioa wUh tIle media ad other parties (ladacUDl foellaC aaeadts) 01ltÂCle the JWDed J'eIIU'dltra .. d the coIDmmdty wIU be Ilacllecl bt. these agreedways:

In t'ho event of media hlte.rest, prior consent hm the COlDlllumty stccring committec will he obtaiœd bcfbro any infonnation is rcJcucd.

FUNDING, BENEFITS, -" COMMlTMENTS

Fundhal

CINE has acqulred taadÎJllad other torms or support for tIûs researdl proJeet frôm:

Inuit Tapirlit Kanatami and the Max '8eU Foundatioa.

J!eMtlts

CINE wilila to use the curreat projeet ba the followtq ways:

• to leam from the cxpericnce to improve the heallh sc.reenin& logi$ties and quea1ioJmairea wbich wi1l \le med na other Inuit communitics;

• te deve10p a relevant physical a.ctivity questi~ that can bc uscd in hcaHh and hca1th promotion rescarch in Inuit eommunities;

• to c1evelop an underatanding of how diet and othcr factors are related fO pre­diabctic ccmditiœa and to ptesent infnrmatioa on tbeso findings at health confer:mx:es and in scientifie hea1thjouroals;

• to iosœt indMdual and comm.UDity interest in healtb promotion and evaluation of hca1th promotion cftbrts.

Bcne1its likcly 10 he gaincd by the community tbrough ibis project are educatiooal in ~ in that the ptOject Wl11 raiso individual mc1 <X>IlUl1UDity awarencss of cum:nt hea1th status sa tbat the community can decide upon appropriate activitiea to ptOmOte health.

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CommJtmegtl

ne communlty'. eommUmedts to CINE are 10:

• Conn a conummity projeot stceriug committee for the bealth scrccning projeot (donc).

• recOl11IlleDd capable aM reliable community membets to ~llabol'lkl'bc cmploYQd in thi& project (donc);

• recommetld lDd guide losistics md queationoairc devc1opm«lt aud to help e<munuaiClte RSUlts back tO the community and iDdividuaJs (donc);

• keep intonDcd on the project pmgress, aQd help in lcading the ptOject toward meanin&fùl results (~.

• provide a location for the hcalth seteeDing (done).

The CINE npreseatatlYa' (Grace EpIad.) l8d her atadmtl (Guylalae CilarbODDeaD, Se Blrd, lDd Daeea Dea.ome) COIIlIIIftmeIlb to the comm:aJdty.re to:

• CoDduct tœ ptOjtct With caro and respect and 10 keep personal information cnn6demia1;

• Infi>rm the coaummity as to the projeet pmgres$ in a clcar and time1y DlIDDet;

• Act as ~ 10 the community for nutrition and hca1th relaùld questions.

CINE agrees te atop the projcçt if comrmmity lcad«s decide ta withdtaw paniclpation, or if the project is succe.ssMly eomplttbd. ft Ï$ understood tbat a timate healtb promotion <:ampaigtl and evaluati.0Il depcnd. upon finding addidonal fUnding.

Signedby:

Cij-' ~. t7~apik Mt)'Ol'. Hamlet ofPangnirtung

~/,:L/ GraQc Egclaiul CINE

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Appendix 3: Pangnirtung health screening informed consent

forms in English and Inuktitut

72

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INFORMED CONSENT FORM Pangnirtung Health Screening

Principal Investigator: Grace Egeland Ph.D., Centre for Indigenous Peoples' Nutrition and Environment (CINE), McGill University. Co-Investigator: Dr. Kue Young, Department of Public Health Sciences, University of Toronto, Guylaine Charbonneau­Roberts, P.Dt., M.Sc. candidate, CINE, McGill University. Responsible Institution: CINE, McGill University. Pangnirtung Community Steering Commlttee: Markus Wilcke, Johnny Kuluguqtuq, Donna Kilabuk, and Jonah Kilabuk. Otber eoOaborators: Looee Okalik, Inuit Tapiriit Kanatami.

Introduetion: We are conducting a health screening to find out blood sugar levels and what factors predict high blood sugar leveIs among the Inuit. Ail Inuit adults over the age of 18 years living in your community are invited to be part of the health screening. This consent fonn will give you a general idea of what the health screening project is about and what your participation involves. Please take the time to read the information carefully and make sure that you understand il

Purpose: This screening bas two main objectives: 1. To find out how many people have high blOOd sugar in Pangnirtung; 2. To find out why some Inuit may have a greater chance of getting high blood sugar.

Description of the study: AIl participants will be asked to visit the Arctic College where an Inuktitut and English speaking team will carry out a health screening. You will be asked about the kinds of food you are eating during a short interview and then you will be asked to come to the c1inic in the moming after an overnight fast (a minimum of 8 hours without eating) for about 3 hours. The health screening will include the following: 1. Face-to-face interview

• Physical activity • Personal and family medical history • The kinds of foods you normally eat

2. Body measurements • Body weight • Body fat composition (for this it will he necessary that you remove your shoes and socks) • Height and Sitting height • Waist circumference (directly against your skin)

3. Clinical and laboratory measurements • Blood pressure and heart rate • Blood samples (after the overnight fast) • Take a sweet drink • A blood sample will be taken two hours after drinking the sweet drink

Your blood will he tested for: • fasting insulin (to find out how well your body can carry sugar and supply your body with

energy); • fasting glucose (sugar); • good and bad fats in your blood; • glucose (sugar) level2 hours after you drink a sweet drink; • adiponectin (shows what the chances are for a person to have high blood sugar problems later

in life).

InitiaIs of participant: __ 5110/05

InitiaIs of witness: Page 1 of3

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No more than 3 tablespoons (44 ml) ofhlood will he taken for this study and no amount ofhlood will he placed in long-term storage for future tests. No other laboratory tests will he done.

Right to refuse participation: Your decision to be part of the study is completely up to you.

Risks of participating: • A bruise or tendemess where blood was taken. • Symptoms related to low blood sugar after drinking the sweet drink, such as weakness,

fatigue, and hunger, and in some cases, anxiety, nervousness, trembling. These symptoms are easily treated hy the nurse and can be avoided by taking a light lunch which will be provided to you at Arctic College at the end of the health screening.

Reason why it may be useful to you to be part of this research: After successfully finishing all parts of the health screening, you will receive your results in a booklet (in English and Inuktitut) within 2 months. A general summary of the results will al50 be presented to the community in the faU 2005. Everyone participating will receive information about how to prevent high hlood sugar. You will al50 receive a CINE baseball cap and your name will he put in a draw for a variety of prizes.

Confidentiality: • The interviewers have signed a confidentiality agreement and the data collected is confidential. • You will be given a unique number to keep your identity confidential. • We will keep a copy ofyour name in a locked cabinet in the Centre for Indigenous Peoples' Nutrition and Environment (CINE) director's office 50 that your results can he returned to you. • Once your results are returned to you, your name and birth date will be removed from the database which will be used for the summary report; only your number will be given to those looking at the data. • If you agree, your personal medical results will be given to the Pangnirtung Health Center. • No other personal information will he shared with any community member, organizations or other agencies. • Only the overall findings (not your personal results) will be shared with regional and national Inuit organizations concemed with health.

Right to withdraw: Your participation is voluntary and you can stop being part of the studyat any time. Also, it is okay if you do not answer some of the questions. Please ask any memher of the health screening team if there is 50mething that you do not understand. Al5O, you own your personal data and can at any time ask to have your own personal data removed from the datahase.

For more information, comments, complaints or to withdraw from the study, please contact: Susa Qappik, Phone number: (867) 473-8567 Jojo Aningmiuq, Phone number: (867) 473-8559 Johnny Kuluguqtuq, Phone number: (867) 473-2632 Grace Egeland, Ph.D. Phone number: (514) 398-8642 Kue Young, M.D. Phone numher (416) 978-6459

InitiaIs of participant: __

5110/05 Initiais of witness:

Page 2 of3

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INFORMED CONSENT FORM Pangnirtung Healtb Screening

1 have read and understood what is involved in the study and agree to participate in the Pangnirtung Hea1th Screening.

YesD NoD

1 give permission to the Pangnirtung Hea1th Screening to send my medical results (blood pressure, blood fat, and blood sugar levels) of the health screening to a medical representative at my local health clinic.

YesD NoD

1 give permission to the Pangnirtung Hea1th Screening to find out if my blood sugar has been tested in the past and what my results were. 1 give permission for my full name, date of birth, and hea1th number to be used to find out my information at the Baffin Regional Laboratory (based in Iqaluit).

Yes 0 Hea1thNumber: _______ _ No D 1 give permission to the Pangnirtung Health Screening to contact me within the next 5 years for a follow-up hea1th screening.

Name of participant

Name ofwitness

Name of principal investigator lor bis designated representative

YesO

Signature

Signature

Signature

NOO / /

Date (ylmld) --

_/_/­Date (ylmld)

Participant's address where results are to be sent and phone number

A copy of this consent form has been provided for you. Please keep it for your records and future reference.

Consent explained by: _________ _ Date (ylmld): _______ _

Questions answered by: _________ _ Date (ylmld): _______ _

Initiais ofparticipant: __ Initiais of witness: 5/10/05 Page 3 of3

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ccnn. <lc-" <l'''?C <""cr'ijr ,,~~~ 'icroa. nr~< 'ib.DA'" cr""L.D'"

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5/10/0S Page 1 of3

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)Pr'r<lba-?LJN, t>lbl>r'L., Ib?N, <lb 1> '" 'C'dN NL "a-?N Ibt> .... '" ICI>a-1J", IbI> .... b? .. a.X.h..c a..e-<l).h.. .. a.. lb rL., ibN, I>lbc...l>n'l., (867) 473-8567 -.!-.! <l''a-1rl>lb, I>lbc...l>n'l., (867) 473-8559 !ra- d .... ~?I)Ib, I>lbc...l>n'l., (867) 473-2632 JGt." t.!Tc.... .. (Grace Egeland), Ph.D. 1>%c....l>n ... L (514) 398-8642 J !rb (T. Kue Young), M.D. I>lbc...l>n'l., (416) 978-6459

5/10/05 Cl...-,0....6.(r'<T"L ccr-a....~)<:

Page 2 0f3"

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Appendix 4: Physical activity validation study informed

consent forms in English and Inuktitut

73

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INFORMED CONSENT FORM Physical Activity Validation Stndy

Principal Investigator: Grace Egeland Ph.D., Centre for Indigenous Peoples' Nutrition and Environment (CINE), McGill University. Co-investigator: Daneen Denomme M.Sc. candidate, McGill University. Responsible Institution: CINE, McGill University. Pangnirtung Community Steering Committee: Markus Wilcke, Johnny Kuluguqtuq, Donna Kilabuk, J onah Kilabuk. Other collaborators: Looee Okalik, Inuit Tapirit Kanatarni.

Introduction: We are looking for people who have volunteered to be in the Pangnirtung Health Screening project to be part of this study. Please take the time to read this consent form and make sure that you understand it.

Purposes: 1. To use a questionnaire and a physical activity recorder to measure physical activity levels

among Inuit.

Description of the study: The results from the physical activity questionnaire that you will fill out as part of the Health Screening will be compared to the results of an activity monitor.

You will be asked to do two things: 1. Come to the Arctic College to get your height and weight measured. 2. Wear a small physical activity recorder called a Caltrac that will measure your physical

activity. You will be asked to wear this for seven days in a row. It clips onto your belt or pants at your waist and is about the size of a deck of cards.

Important things to think about: • Wearingthe Caltrac activity monitor will not cause you any harm. • The results will be entered into a computer pro gram but it will not include your name; you

will be given a number instead so that the people working with the results will not know your name.

• We will keep a copy of the names of participants in a locked cabinet in the Centre for Indigenous Peoples' Nutrition and Environment (CINE) director's office so that results can be returned to the individuals participating in the health screening. (REMOVE)

• No personal information will be shared with any community member, organizations or other agencies.

• The findings will not include names or any information that can be used to identify individuals.

• Only the overall findings (not your personal results) will beshared with regional and national Inuit organizations concemed with health. * You have the right to stop being in the study at any time and to withdraw aIl of your

information.

Benefits ofbeing in this study: 3. You will be helping to make physical activity measuring simpler and more accurate in the

future. Everyone participating will get information about how to prevent obesity. You will also be given two extra raffle tickets for the draw. You can double your chances ofwinning!

InitiaIs of participant: __ 5/10/05

InitiaIs of witness: 0-'2.­Page 1 of 2

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INFORMED CONSENT FORM Pangnirtung Health Screening - Physical Activity Validation

l have read and understood what is involved in the study and agree to participate in the Physical Activity Validation Study.

YesD NoD

Name of participant

Name ofwitness

Name of principal investigator for bis designated representative

Signature

Signature

Signature

/ / ------Date (y/mJd)

/ / ------Date (y/mJd)

_/_/­Date (yfmld)

Participant's address where results are to be sent and phone number

A copy of this consent fOrIn has been provided for you. Please keep it for yOUf records and future reference.

Consent explained by: __________ _ Date (yfmJd): _______ _

Questions answered by: ~ ________ _ Date (ylmJd): _______ _

For more information, comments, and complaints or to withdraw from the study, please contact: Susa Qappik, Phone number: (867) 473-8567 Jojo Aningmiuq, Phone number: (867) 473-8559 Johnny Kuluguqtuq, Phone number: (867) 473-2632 Grace Egeland, Ph.D., Phone number: (514) 398-8642

Initiais ofparticipant __ 5110/05

Initiais ofwitness: __ Page 2 of 2

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• A -.!"a... ~a-"b ~dnc "b '\.,)11'" a...n <1 dC NbCI>-.!LJ ... a-~a-?N "bl>~~ ~a-~J" ..0 "b?"a... ~dnc.

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Q....;>c~LI.'r'cr't. A"Ct>~< Q....;>o..L\'r'cr't. CO'o..')<; __

5/10/05 Page 1 of2

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een(\. <lC"'"~ <l''''f'?C <"'cr~jr ~bt> .... , ~cr~ nrt>< %..oA o..cr'l...o 0.. - nrt>< <lt>c.. %Ce~cr'l..D 0.. %t> .... r<l?C

t>~'L t>%C'"lVl~'L <ILL )Pr''-...:l 'L Ca.. %t>r--~ ~crq, %..oÂ.cjcr<l~cr'Lcr~ <ILL <l'''f~d'L A %Ct>~lcr~crb <'cr~jr nrt>< %..oÂ. "cr""l..crb %t>r--~ ~cr~J".

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/ / <lGJ't../CIP't../I>'--" 't..

/ / <lC;J't../CIP't../I>~ ..> 't..

/ / <lGJ't../CIP't../I>~..> 't..

<Ir?' a....><>...6.'c't.. I>L: _________ _ <lGJ't../CIP't../I>~ ..>'t..: _______ _

<t\'di" PI>!r'1'~ I>L: _________ _ <I<iJ't../C'P'I./I>"" ..>'1.: _______ _

)Pr'r<lbO"'?LJN, t>"t>r'~ %?N, <lbt>~ "'fdN NL LO"'?N %I>~~ ~CI>O"'IJL, %1>~b?La.. ~CAc a..c-<l)ALa.. q,:

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o....>o..A'r'cr"L A'bCI>~< __

5/10/05 o....>o..A'r'cr"l.. c.r-o..')<: __

Page 2 of2

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Appendix 5: International Physical Activity Questionnaire

(IPAQ) in English and Inuktitut

74

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STUDY NO. 1 N 1 U 1 0 1 1 1

< .... crlijr n rI> < Iib..Db. IL. cr ""l,..D 01.

lib 1> r---" licrlilo 2005

~ c- f~<1fJ nrt> < <1t>C-7l- ~ fCa- ttt-..J:J ... <1l1ync

INT.NO.

Pangnirtung Health Screening 2005

PHYS/CAL ACTIV/TV QUESTIONNA/RE

1 nterviewer -Completed Questionnaire

Centre for Indigenous People' Nutrition and Environment Macdonald Campus of McGiII University

Completion Date: JJL'_'2005 m d y

_ .......... _I ___ L ___ n~

Time:_'_ h m

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INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRE

We are interested in finding out about the kinds of physical activities that people do as part of their everyday lives. The questions will ask you about the time you spent being physically active in the last 7 days. Please answer each question even if you do not consider yourself to be an active person. Please think about the activities you do at work, as part of your house and yard work, to get from place to place, and in your spare time for recreation, exercise or sport.

Think about ail the vigorous activities that you did in the last 7 days. Vigorous physical activities refer to activities that take hard physical effort and make you breathe much harder than normal. Think only about those physical activities that you did for at least 10 minutes at a time.

1. Ouring the last 7 days, on how many days did you do vigorous physical activities like heavy lifting, digging, shovèling snow, or fast bicycling?

___ days per week

D No vigorous physical activities __ ... ~ Skip to question 3

2. How much time did you usually spend doing vigorous physical activities on one of these days?

___ hours per day ___ minutes per day

D Oon't know/Not sure

Think about ail of the moderate activities that you did in the last 7 days. Moderate activities refer to activities that take moderate physical effort and make you breathe somewhat harder than normal. Think only about those physical activities that you did for at least 10 minutes at a time.

3. Ouring the last 7 days, on how many days did you do moderate physical activities like carrying small children, fishing, hunting, or dancing? Do not include walking.

___ days per week

No moderate physical activities --... ~ Skip to question 5

4. How much time did you spend doing moderate physical activities on one of those days? ___ h, ours per day ___ ,minutes per day

D Oon't know/Not sure

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Think about the time you spent walking in the last 7 days. This includes at work and at home, walking to travel fram place to place, and any other walking that you might do solely for recreation, sport, exercise, or leisure.

5. Ouring the last 7 days, on how many days did you walk for at least 10 minutes at a time?

___ days per week

Nowalking __ .. ~~ Skip to question 7

6. How much time did you usually spend walking on one of those days?

___ ,hours per day ___ minutes per day

D Oon't know/Not sure

The last question is about the time you spent sitting on weekdays during the last 7 days. Include time spent at work, at home, while doing course work and during leisure time. This may include time spent sitting at a desk, visiting friends, reading, or sitting or Iying down to watch television.

7. Ouring the last 7 days, how much time did you spend sitting on a week day?

___ hours per day ___ ,minutes per day

D Oon't know/Not sure

8. Compared to the last 7 days, are you usually:

D More active

D Same

D Less active

D Don't know/Not sure

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STUDY NO. 1 N 1 U 1 0 1 1 1

<'""crc;jr nrl>< c;b..Dâ .... cr'L..D'"

c;bl>~~ c;crq, 2005

~ C- f~<Jr n,t> < <Jt>C-71., 'li f(h- ""l.,..,D "­<JAyne

INT.NO.

Pangnirtung Health Screening 2005

PHYS/CAL ACTIV/TV QUESTIONNA/RE

Interviewer-Completed Questionnaire

Centre for Indigenous People' Nutrition and Environment Macdonald Campus of McGiII University

Completion Date: 05 '_'2005 m d y

Time:_'_ h m

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