Question 1

1.

Which is a component of cocktail therapy vs.

AIDS?

Answer

Amantadine

Zidovudine

Acyclovir

Vancomycin

Ribavirin (virozole)

1 points

Question 2

1.

Atropine can induce

Answer

"tachycardia, dry mouth"

"bradycardia, miosis"

"tachycardia, salivation"

"tachycardia, miosis"

"bradycardia, salivation"

1 points

Question 3

1.

Lugols Solution (Iodine) can be used to

treat

Answer

hyperthyroidism

hypogonadism

allergy

diabetes

hypothyroidism

1 points

Question 4

1.

After long-term use of Glucocorticoids,

rebound phenomenon will occur if the dosage

is reduced rapidly, it is because

Answer

adrenal suppression

iatrogenic Cushing syndrome

glucocorticoid dependence

increased ACTH secretion

decreased pituitary function

1 points

Question 5

1.

Which drug is addictive antitussive

Answer

Ammonium chloride

Dextromethorphan

Benzonatate

Codeine

Pentoxyverine

1 points

Question 6

1.

Pharmacological mechanism of Cardiac

Glycosides is

Answer

Inhibition of cAMP

Inhibition of H+-K+-ATPase

Inhibition of Na+-K+-ATPase

Inhibition of P-450

Inhibition of Phosphodiesterase

1 points

Question 7

1.

Which drug can be used for abortion

Answer

Prostaglandins

Ritodrine

Ergometrine

Oxytocin

Indomethacin

1 points

Question 8

1.

Which of the following drugs can inhibit the

DNA-dependent RNA polymerase?

Answer

Penicillin G

Rifampin

Streptomycin

Chloramphenicol

Cefoperazone

1 points

Question 9

1.

The effect of Cholestyramine on blood lipid

is

Answer

Reduce TC and LDL-C

Reduce TG and HDL

Reduce CE and FFA

Reduce TC and VLDL

Reduce TC and CM

1 points

Question 10

1.

Which one is NOT a main adverse effect of

Streptomycin?

Answer

Nephrotoxocity

Vestibular toxicity

Hepatotoxicity

Neuromuscular Paralysis

Cochlear toxicity

1 points

Question 11

1.

The most active aminoglycoside against

Mycobacterium tuberculosis is

Answer

Kanamycin

Neomycin

Amikacin

Streptomycin

Tobramycin

1 points

Question 12

1.

The H2 receptor antagonists are mainly used

to

Answer

hypertension

asthma

diabetes

intestinal spama

peptic ulcer

1 points

Question 13

1.

Which pathogen is susceptible to

Azithromycin?

Answer

Plasmodium

G coccus

G bacillus

Rickettsia

Anaerobic bacteria

1 points

Question 14

1.

The most important mechanism of

Cephalosporins acquired resistance is

Answer

the change of metabolism pathway

produce the -lactamases

reduction of cell membranes perrmeability

active efflux system

modification of target sites

1 points

Question 15

1.

Which drug has the mucoprotective effect for

ulcer treatment

Answer

Ranitidine

Magnesium trisilicate

Omeprazole

Atropine

Sucralfate

1 points

Question 16

1.

The correct time for alternate-day

adiministration of Glucocorticoids is

Answer

4:00 AM

8:00AM

8:00 PM

4:00 PM

12:00 AM

1 points

Question 17

1.

The common effect of Nitroglycerin and

Propranolol in angina treatment is

Answer

decrease heart rate

decrease peripheral resistance

decrease myocardiac contraction

decrease myocardiac oxygen consumption

decrease ventricular volume

1 points

Question 18

1.

Which of the following effect is the adverse

drug effect of Heparin

Answer

Peptic ulcer

Pypertension

Asthma

Bleeding

Abnormalities of renal function

1 points

Question 19

1.

Which of the following antibacterial agents

can inhibit folic acid metabolism?

Answer

Quinolones

Aminoglycosides

Clindamycin

Cephalosporins

Sulfinamides

1 points

Question 20

1.

Which one is NOT the clinical use of Oxytocin

Answer

induction of labor

induction of abortion

augmentation of labor

promote milk ejection

postpartum hemorrhage

1 points

Question 21

1.

Which one is rapidly effective for acute

asthmatic attack

Answer

oral administration of Aminophylline

Cromoglicate sodium

Aalbutamol inhalation

Beclomethasone

Ketotifen

1 points

Question 22

1.

Valsartan is

Answer

Ca2+ channel blocker

-blockers

Cardiac Glycosides

Angiotensin II receptor blockers (ARBs)

Angiotensin-Converting Enzyme Inhibitor(ACEI)

1 points

Question 23

1.

For the roundwarm and pinwarm infection,

preferred drug is

Answer

Praziquantel

Levamizole

Mebendazole

Piperazine

Pyrantel

1 points

Question 24

1.

Penicillin G is the 1st choice against

Answer

Gbacillus

Hemolytic Streptococcus

Mycobacterium tuberculosis

Enterococci

Shigellosis

1 points

Question 25

1.

The mechanism action of Heparin is

Answer

block the Ca++ action

active the ATIII

counteract to the VitK

antagonize the VitK effect

"inhibit the synthesis of thrombin II , IX, X"

1 points

Question 26

1.

A 35-year-old female complains of itching in

the vulval area. Hangingdrop examination of

the urine reveals trichomonads. What is the

preferred treatment for trichomoniasis?

Answer

Emetine

Metronidazole

Pyrimetamine

Pentamidine

Doxycycline

1 points

Question 27

1.

The mechanism of Glucocorticoids for asthma

treatment is

Answer

stimulate respiratory centre

activate adenyl cyclase

dilate airway smooth muscles

anti-inflammation and anti-allergy

block M-receptor

1 points

Question 28

1.

Adverse Effects of Angiotensin Converting

Enzyme (ACE) Inhibitors are NOT including

Answer

Ventricular bradycardia

Hypotension

Hyperkalemia

Angioneurotic edema

Cough

1 points

Question 29

1.

What is the mechanism action of Zidovudine

Answer

Inhibition of nucleoside reverse transcriptase

Inhibition of DNA synthesis

Inhibition of viral particle assembly

Inhibition of RNA synthesis

Inhibition of viral proteases

1 points

Question 30

1.

Which agents using should be cautious about

or avoided while patient underwent kiney

malfunction?

Answer

Penicillins

Macrolides

Tetracyclines

Aminoglycosides

Chloramphenicol

1 points

Question 31

1.

The mechanism of action of Biguanides is

Answer

increase the glycagon effect

decrease insulin resistance

enhance the glucose uptake and catalyzing by peripheral

tissues

stimulating insulin release from pancreatic cells

promote the glucose to catalyze

1 points

Question 32

1.

Cardiac output is best increased by

stimulation of

Answer

beta1 receptors

muscarinic receptors

beta2 receptors

alpha2 receptors

alpha1 receptors

1 points

Question 33

1.

The Thioureas can be used for

Answer

hypothyroidism

diabetes

hyperthyroidism

hypogonadism

allergy

1 points

Question 34

1.

Which one is NOT a first-line

antituberculosis agents?

Answer

Isoniazid

Ethambutol

Rifampin

Pyrazinamide

Amikacin

1 points

Question 35

1.

The mechanism of action of Sulfonylureas is

Answer

increase the glycagon effect

decrease insulin resistance

inhibit the insulin effect

promote the glucose to catalyze

stimulating insulin release from pancreatic cells

1 points

Question 36

1.

Which description about Generation III

Quinolones is WRONG?

Answer

Levofloxacin is most effective vs. G germs in the family

They act against G germs by inhibiting DNA gyrase

They are chlorine derivatives of Pipemidic acid

They act against G germs by inhibiting DNA topoisomerase IV

They have strong activity against G germs

1 points

Question 37

1.

Which agent act against bacteria mainly by

interfering functions of cell membrane?

Answer

ciprofloxacin

polymyxin B

streptomycin

erythromycin

tetracycline

1 points

Question 38

1.

Which drug is effective against either

systemic or superficial fungal infection?

Answer

Flucytosine

Ketoconazole

Nystatin

Amphotericin B

Ribavirin

1 points

Question 39

1.

Which one in the following drug is best to

treat hypertension crisis

Answer

Spironolactone

Losartan

Sodium Nitroprusside

Captopril

Hydrochlorothiazide

1 points

Question 40

1.

Hypokalaemia occurs with the following drugs

Answer

Captopril

Bumetanide

Nifedipine

Carbonic anhydrase inhibitors

Spironolactone

1 points

Question 41

1.

Prodrug-requires activation by microsomal

enzyme system

Answer

cyclophosphamide (Cytoxan)

chlorambucil (Leukeran)

thiopeta (Thioplex)

mechlorethamine (Mustargen)

semustine (methyl CCNU)

1 points

Question 42

1.

Why the clinical use of Choloramphenicol is

limited in infectious disease?

Answer

Severe adverse effects such as irreversible marrow inhibition

Low bioavailability

Most bacteria have developed drug resistance

Low efficiency in suppressing bacteria

Severe allergic shock

1 points

Question 43

1.

Which one does NOT have the effect of

antiplatelet aggregation

Answer

Aspirin

Wafarin

Dipyridamole

Ridogrel

Epoprostenol

1 points

Question 44

1.

Which of the following is NOT the adverse

effects of Glucocorticoid ?

Answer

poor wound healing

asthma

"buffalo hump, moon face"

osteoporosis

hypertension

1 points

Question 45

1.

Omeprazole is belonged to

Answer

H1 receptor antagonists

H2 receptor antagonists

M receptor antagonists

Mucosal protective agents

H+-K+-ATPase (Proton pump) inhibitor

1 points

Question 46

1.

A 25-year-old female post-renal transplant

shows signs of acute renal allograph

rejection. Of the following agents, which

should be administered?

Answer

Acyclovir

Interleukin-2

Levamisole

Interferon

Cyclosporin A

1 points

Question 47

1.

By which target Aminoglycosides interfered

with protein synthesis of bacteria?

Answer

stage of peptide strands exfliation

stage of termination

all stages of protein synthesis

stage of initiation

stage of peptide strands elongation

1 points

Question 48

1.

The phase of the cell cycle that is resistant

to most chemotherapeutic angents and

requires increased dosage to obtain a

response is the

Answer

S phase

M phase

G0 phase

G1 phase

G2 phase

1 points

Question 49

1.

Which one in the following drugs is

preferable to use to treat Paroxysmal

supraventricular tachycardia

Answer

Amiodarone

Verapamil

Procainamide

Lidocaine

Atropine

1 points

Question 50

1.

Competitive inhibitor of

3-hydroxy-3-methylglutaryl coenzyme A

(HMG-CoA) reductase is

Answer

Cholestyramine

Ezetimibe

Simvastatin

Acetazolamide

Nicotinic acid

1 points

Question 51

1.

The effect mechanism of expectorant

Acetylcystein is

Answer

breakdown the viscous component of the sputum

decrease the protein secretion in the airway

increase airway fluid secretion

increase airway ciliary movement

decrease sputum secretion

1 points

Question 52

1.

Which of the following description about the

clinical uses of Glucocorticoid is WRONG

Answer

inhibit the growth of bacteria

anti-shock

anti-inflammatory effects

immunosuppressive effects

anti-allergic effect

1 points

Question 53

1.

Which drug can Increase nitric oxide (NO)

Answer

lonidine

Aldosterone Antagonists

Nifedipine

Methyldopa

Nitroprusside

1 points

Question 54

1.

Which drug is most effective against systemic

fungal infection?

Answer

Terbinafine

Nystatin

Clotrimazole

Amphotericin B

Griseofulvin

1 points

Question 55

1.

Which of the following drugs is the first

choice for the treatment of type I diabetes?

Answer

Angiotensin Converting Enzyme (ACE) Inhibitors

Insulin

Sulfonylureas

Acarbose

Biguanides

1 points

Question 56

1.

Which one in the following drugs is highly

efficacious diuretics

Answer

Spironolactone

Acetazolamide

Hydrochlorothiazide

Triamterene

Furosemide

1 points

Question 57

1.

To treat bleeding induced by Warfarin, which

drug can be used

Answer

Urokinase

Vit K

Vit B12

Dipyridamole

Protamine

1 points

Question 58

1.

Which agent is The 1st choice against MRSA?

Answer

Amoxicillin

Generation 1 Cephalosoprins

Vancomycin

Penicillin G

Erythromycin

1 points

Question 59

1.

Gentamicin inhibit bacterial protein

synthesis by binding

Answer

30S ribosomal particles

Messenger RNA

RNA polymerase

Peptidoglycan units in the cell wall

DNA polymerase

1 points

Question 60

1.

The most effective drug to inhibit gastric

acid secretion is

Answer

Calcium carbonate

Cimetidine

Proglumide

Pirenzepine

Omeprazole

1 points

Question 61

1.

Compare antibacterial characteristics of 4

generations of Cephalosporins.

Answer

Question 62

1.

What is the clinical uses of Calcium Channel

Blockers(CCBs).

Answer

Question 63

1.

List the adverse drug reactions (adverse

effects) of Glucocorticoids in long-term

use.

Answer

Question 64

1.

Please describe the therapeutic strategies

and drugs for Peptic Ulcer.

Answer

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