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Pharma infoAIMING THE FUTURE !!!.

(For GPAT and NIPER JEE)

GPAT & NIPER JEE Test series Total 45 Test Papers for All syllabus covered according to GPAT 2012 ( As per MSU ,Vadodara) Test series + key Notes with each Test Papers How to prepare for test with Reference Book All test papers are prepared according to Questions asked in GPAT examination Easy revision for all subjects cover in GPAT syllabus During each Subjects test Papers Revision test Total Revision for All GPAT syllabus Rapid Revision Booklet for GPAT Imp tables & charts for GPAT At last Previous papers for GPAT 2010 & 2011 Fees: 1600/- only

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Pharma info

Test Schedule for Pre-GPAT 2012

1. Pharmaceutical analysis

Division : Topic and Sub Topic Code PaperNo

1.UV + IR + NMR + Mass : Basics, Principle, Theory, Application, Numericals etc. PA-1

01

2. Other Analytical Techniques (Instrumental) Potentiometric titrations, Conductometry, Coulometry, Polarography, Amperometry,

Fluorimetry, Flame Photometry, Atomic Absorption Spectroscopy, X-ray Diffraction Analysis, Radioimmunoassay

PA-2 02

3. Chromatography HPLC , GC, TLC, Paper, Gel, ion exchange, HPTLC and Column Chromatography PA-3 03

4. Noninstrumental Analytical Techniques Acid base titrations, redox titrations, gravimetry, oxygen flask combustion method,

Karl Fisher titrations, non aqueous titrations. PA-4 04

5. All Pharmaceutical analysisPA-5 05

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2. Pharmaceutics

1. A Capsule+Tablet+ Suspension Theory, Manufacturing, Quality-Control, Stability, Problems and resolutions

1. B. Preformulation Studies Physical and chemical properties of drugs and their effect on formulation and

stability.

PT-1 06

2.A. Semisolid+Emulsion +Suppository+Parenteral+Cosmetics + Aerosol Theory, Manufacturing, Quality-Control, Stability, Problems and resolutions

2.B. Types of dosage form e.g. mixtures, solutions, creams, ointments, powders, capsules, pastes, jellies, suppositories, ophthalmic, pastilles, lozenges, pills, lotions, liniments, inhalations, paints sprays tablet triturates, etc

PT-2 07

3. Biopharmaceutics Absorption, Distribution, Metabolism, Elimination, Prodrug, BA and BE, Protein

binding, Biopharmaceutical Classification System (BCS) of drugs, Compartment modelling

PT-3 08

4. A. Physical Pharmacy Micromeretics and Powder Rheology, Surface and Interfacial Phenomenon,

Dispersion, Kinetics and Drug Stability 4.B. Incompatibilities

Physical, chemical and inorganic incompatibilities, correction of incompatibilities

PT-4 09

5. Unit operation Stoichiometry, Fluid Flow, Heat transfer, Evaporation, Distillation, Drying, Size

Reduction, Mixing, Filtration and Centrifugation, Dehumidification and Humidity Control, Material of Construction applications of the materials of construction with special reference to stainless steel, Plastics and glass

PT-5 10

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6.A. Calculations in Pharmaceutics 6.B. Indian Pharmacopoeia Various dosage forms testing requirements, specification, labelling, storage

PT-6 11

Analysis + P'ceutics Complete Syllabus of both subjects M-1 12

3. Pharmaceutical Medicinal chemistry

1. CVS Cardiotonic,Anti-anginal,Anti-hyperlipidemic,Anti-hypertensive,Anti-arrythmic,Anti-

diabetic,Anti-coagulant and anti-platlet..agent MC-1 13

2. CNS General and local anaesthetic ,Anti-psychotic,Anti-anxiety,Anti-parkinsonism,Sedative-

hypnotic,Anti-depressent,NSAIDS,Opiod-analgesic,Anti-convulsant,CNS-stimulant. MC-2 14

3. ANS + AntiHistamine + Diuretics +Steroids and Hormones. Cholinergic sysyem and Adrenergic system. Ganglion and neuromuscular blocker. MC-3 15

4. chemotherapy: Antibiotics: ß-Lactam, macrolides, tetracyclines, aminoglycosides, polypeptide

antibiotics, fluoroquinolones, Anti-metabolites (including sulfonamides); Anti-neoplastic agents; Anti viral agent,Anti fungal and prtozoal..and imuuno suppressive agent.

MC-4 16

5. Organic chemistry (According to GPAT-2011 Syllabus) MC-5 17

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6. Inorganic + Physical Chemistry(According to GPAT-2011 Syllabus) MC-6 18

Analysis + P'ceutics + Med.Chem Complete Syllabus of all three subjects M-2 19

4. Pharmacology

1. A. General + Receptors, Pharmacokinetics, Pharmacodynamics, Routes of administration, adverse

drug reaction, new drugs, bioassay of drugs

1. B. ANS

Parasympathomimetics, Parasympatholytics, Sympathomimetics, Adrenergic receptor and neuron blocking agents, Ganglion stimulants and blocking agents, Neuromuscular blocking Agents, Local anesthetic Agents

PL-1 20

2. CNS General Anesthetics, Alcohol and disulfiram, Sedatives, Hypnotics, Anti-anxiety agents

and Centrally acting muscle relaxants, Psychopharmacological agents (anti-psychotics), Antidepressants, Anti-epileptics drugs, Anti-Parkinsonian drugs, Analgesics, Antipyretics, Narcotic analgesics and antagonists, Drug Addiction and Drug Abuse

PL-2 21

3. Chemotherapy General Principles of Chemotherapy, Sulfonamides and cotrimoxazole, Antibiotics-

Penicillins, Cephalosporins, Aminoglycosides, Chloramphenicol, Macrolides, Tetracyclines, fluoroquinolones, Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases, HIV and AIDS, urinary tract infections and sexually transmitted diseases, malaria, Chemotherapy of malignancy and immunosuppressive agents.

PL-3 22

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4. CVS Antihypertensive drugs, Anti-anginal and Vasodilator drugs, including calcium channel

blockers and beta adrenergic antagonists, Anti-arrhythmic drugs, Anti-hyperlipedemic drugs, Anticoagulant, Fibrinolytic and anti-platelet drugs

PL-4 23

5. A. Hormones Thyroid hormones and anti thyroid drugs, parathormone, calcitonin and Vitamin D,

Insulin, glucagons, incretins, oral hypoglycemic agents and insulin analogs, Androgens and anabolic steroids, Estrogens, progesterone and oral contraceptives, Thyroid hormones and anti thyroid drugs

5. B. Pathophysiology Basic Mechanisms involved in the process of inflammation and repair, Pathophysiology

of Disorders of Cardio Vascular, Endocrine and Central Nervous System

PL-5 24

6. A. Clinical Pharmacy Drugs used during infancy and in the elderly persons (Pediatrics &Geriatrics), Drugs

used during pregnancy, Drug induced diseases, The basics of drug interactions

6. B. Toxicology General principles of clinical toxicology, poisoning with particular reference to

barbiturates, opioids, organophosphorous poisoning 6. C. Miscellaneous topics

Drugs for respiratory disorders, drugs for GIT disorders and joint disorders

PL-6 25

Analysis + P'ceutics + Med.Chem + P'cology

Complete Syllabus of all four subjects

M-3 26

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5. Pharmacognosy

1. A. Alkaloids Basics of extraction and isolation methods Classification and types of alkaloids Pyridine-piperidine: Tobacco, areca and lobelia. Tropane: Belladonna, hyoscyamus,

datura, duboisia, coca and withania. Quinoline and Isoquinoline: Cinchona, ipecac, opium. Indole: Ergot, rauwolfia, catharanthus, nux-vomica and physostigma. Imidazole: Pilocarpus. Steroidal: Veratrum and kurchi. Alkaloidal Amine: Ephedra and colchicum. Glycoalkaloid: Solanum. Purines: Coffee, tea and cola.

1. B. Enzymes Biological sources, preparation, identification tests and uses of the following enzymes:

Diastase, papain, pepsin, trypsin, pancreatin.

1. C. Marine Pharmacognosy Various molecules from marine sources and their uses.

PG-1 27

2. A. Volatile oil General chemistry, Classification, B.S., CC, Use and Adulteration of: Mentha, Coriander,

Cinnamon, Cassia, Lemon peel, Orange peel, Lemon grass, Citronella, Caraway, Dill, Spearmint, Clove, Fennel, Nutmeg, Eucalyptus, Chenopodium, Cardamom, Valerian, Musk, Palmarosa, Gaultheria, Sandal wood.

2. B. Traditional medicines Common vernacular names, botanical sources,chemical nature of chief constituents,

pharmacology,common uses of: Amla, Kantkari, Satavari, Tylophora, Bhilawa, Kalijiri, Bach, Rasna, Punamava, Chitrack, Apamarg, Gokhru, Shankhapushpi, Brahmi, Adusa, Atjuna, Ashoka, Methi, Lahsun, Palash, Guggal, Gymnema, Shilajit, Nagarmotha and Neem

PG-2 28

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3. A. Glycosides Method of extraction, Classification and types of glycosides

Saponins : Liquorice, ginseng, dioscorea, sarsaparilla, and senega. Cardioactive glycosides: Digitalis, squill, strophanthus and thevetia, Anthraquinone cathartics: Aloe, senna, rhubarb and cascara, Others: Psoralea, Ammi majus, Ammi visnaga, gentian, saffron, chirata, quassia 3. B. Ayurvedic

Introduction to ayurvedic preparations like Arishtas, Asvas, Gutikas, Tailas, Chumas, Lehyas and Bhasmas.

PG-3 29

4. A. Carbohydrates agar, guar gum acacia, Honey, Isabagol, pectin, Starch, sterculia and Tragacanth

4. B. Lipids Bees wax, Castor oil, Cocoa butter, Codliver oil, Hydnocarpus oil, Kokum butter, Lard,

Linseed oil, Rice, Bran oil, Shark liver oil and Wool fat

4. C. Resins Colophony, podophyllum, jalap, cannabis, capsicum, myrrh, asafoetida, balsam of Tolu,

balsam of Peru, benzoin, turmeric, ginger

4. D. Tannins(B.S., C.C., USE, Common identification tests for each class) Classification and differentiation between hydrolysable and condensed tannins :

Gambier, black catechu, gall and myrobalan

PG-4 30

5. A. Microscopy Common microscopical characters of leaf, bark, stem, root, umbelliferous fruit, seed.

Detailed microscopy of Leaves: senna, datura, belladonna, hyoscyamus, digitalis, vinca. Bark:cinnamon, cinchona, cassia, kurchi,etc. Root and rhizome: liquorice,diascoria. fruit: umbelliferous. Seed: nuxvomica.

PG-5 31

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5. B. PTC Factors influencing cultivation of medicinal plants, Types of soils and fertilizers of

common use. Pest management and natural pest control agents, Plant hormones and their applications, Polyploidy, mutation and hybridization with reference to medicinal plants.

Plant Tissue Culture: Historical development of plant tissue culture, types of cultures, nutritional requirements, growth and their maintenance. Applications of plant tissue culture in pharmacognosy.

5. C. Biosynthetic pathway Biosynthetic pathway for amino acid (shikimic acid pathway), terpenoids(melonic acid

pathway), fat and lipids(mevalonic acid pathway). Biosynthetic pathway of Glycosides: Digitoxin, digoxin, hecogenin, sennosides,

diosgenin and sarasapogenin. Alkaloids: Atropine and related compounds, Quinine, Reserpine, Morphine, Papaverine, Ephedrine, Ergot and Vinca alkaloids.

5. D. WHO parameters Chemical identification tests of alkaloids, saponins, cardenolides and bufadienolides,

flavonoids and leucoanthocyanidins, tannins and polyphenols, anthraquinones, cynogenetic glycosides, amino acids

Analysis + P'ceutics + Med.Chem + P'cology + P'cognosy Complete Syllabus of all five subjects M-4 32

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6. Biochemistry + Microbiology + Jurisprudences

Bio chemistry:ATP and its biological significance, Enzymes, Vitamins And Co-Enzymes, Carbohydrate Metabolism, Lipids Metabolism, Biological Oxidation, amino acids, Purine & Pyrimidine. BC-1 33

Microbiology:Identification of Microbes, Disinfection, Sterilization, Immunology and Immunological Preparations, Genetic Recombination, Antibiotics, Microbial Assay as per IP

MB-1 34

Jurisprudences:Pharmaceutical Ethics, Pharmacy Act 1948, Drugs and Cosmetics Act 1940 and Rules 1945 JS-1 35

7. Complete Syllabus:

Complete Syllabus of all subjects C-1 36Complete Syllabus of all subjects C-2 37Complete Syllabus of all subjects C-3 38Complete Syllabus of all subjects C-4 39Complete Syllabus of all subjects C-5 40Complete Syllabus of all subjects C-6 41Complete Syllabus of all subjects C-7 42Complete Syllabus of all subjects C-8 43Complete Syllabus of all subjects C-9 44Complete Syllabus of all subjects C-10 45