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Statistical Methods In Cancer Research. Vol. 2,The Design and Analysis of Cohort Studies. N. E.Breslow and N. E. Day, Eds. International Agency forResearch on Cancer, Lyon, 1987 (distributor, OxfordUniversity Press, New York). xii, 406 pp., illus. $45.IARC Scientific Publications, no. 82. Based on a work-shop, Lyon, France, May 1983.

Structural Modeling by Example. Applications inEducational, Sociological, and Behavioral Research. Pe-ter Cuttance and Russell Ecob, Eds. Cambridge Univer-sity Press, x, 319 pp., illus. $47.50.The T-Cell Receptors. Tak W. Mak, Ed. Plenum,

New York, 1988. xviii, 235 PP., illus. $42.50.Th6ories Biologiques. Ethique et Experimentation

en Medecine. Herve Barreau, Ed. Editions du CentreNational de la Recherche Scientifique, Paris, 1988. 262pp., illus. Paper, 120 F. Fondements des Sciences.Three Sclentists and Their Gods. Looking for

Meaning in an Age of Information. Robert Wright.Times Books (Random House), New York, 1988. xii,324 pp. $18.95. Considerations of Edward Fredkin,Edward 0. Wilson, and Kenneth Boulding.Thyroid Autoimmunity. A. Pinchera et al., Eds.

Plenum, New York, 1987. xvi, 638 pp., illus. $95. Froma symposium, Pisa, Italy, Nov. 1986.The Time Domain in Surface and Structural

Dynamics. Gary J. Long and Femande Grandjean, Eds.Kluwer, Norwell, MA, 1988. xvi, 590 pp., illus. $149.NATO Advanced Science Institutes Series C, vol. 228.From an institute, I1 Ciocco, Italy, June 1987.Towards Understanding Galaxies at Large Red-

shift. Richard G. Kron and Alvio Renzini, Eds. Kluwer,Norwell, MA, 1988. xiv, 347 pp., illus. $96. Astrophys-ics and Space Science Library, vol. 141. From a work-shop, Erice, Italy, June 1987.Trace Amines. Comparative and Clinical Neurobiol-

ogy. A. A. Boulton, A. V. Juorio, and R. G. H. Downer,Eds. Humana, Clifton, NJ, 1988. xx, 476 pp., illus. $75.Experimental and Clinical Neuroscience. From a confer-ence, Isla Margarita, Venezuela, May 1987.The Transfer and Transformation of Ideas and

Material Cufture. Peter J. Hugill and D. Bruce Dickson,Eds. Texas A&M University Press, College Station,1988. xxii, 281 pp. $29.50. Based on a conference,College Station, TX, Nov. 1984.Transformation of Organometallics into Com-

mon and Exotic Materials. Design and Activation.Richard M. Laine, Ed. Nijhoff, Dordrecht, 1988 (U.S.distributor, Kluwer, Norwell, MA). xviii, 288 pp., illus.$96. NATO Advanced Science Institutes Series E,no. 141. From a workshop, Cap d'Agde, France, Sept.1986.Transition Metals and Organometallics as Cata-

lysts for Olefin Polymerization. W. Kaminsky and H.Sinn, Eds. Springer-Verlag, New York, 1988. xx, 442pp., illus. $77.60. From a symposium, Hamburg,F.R.G., Sept. 1987.Transposition. A. J. Kingsman, K. F. Chater, and S.

M. Kingsman, Eds. Published for the Society for GeneralMicrobiology by Cambridge University Press, NewYork, 1988. xvi, 375 pp., illus. $75. Symposia of theSociety for General Microbiology, vol. 43. From asymposium, Coventry, U.K., Apnl 1988.

Ubiquitin. Martin Rechsteiner, Ed. Plenum, NewYork, 1988. xviii, 346 pp., illus. $59.50."Unless You Believe, You Shall Not Under-

stand." Logic, University, and Society in Late MedievalVienna. Michael H. Shank. Princeton University Press,Princeton, 1988. xviii, 257 pp. $35.The Water Planet. A Celebration of the Wonder of

Water. Lyall Watson. Crown, New York, 1988. x, 206pp., illus. $30.The Weather of the 1780s Over Europe. John

Kington. Cambridge University Press, New York, 1988.x, 166 pp., illus. $70.Weather Systems. Leslie F. Musk. Cambridge Uni-

versity Press, New York, 1988. 160 pp., illus. $11.95.Cambridge Topics in Geography.Why We Sleep. The Functions of Sleep in Humans

and Other Mammals. James Home. Oxford UniversityPress, New York, 1988. x, 319 pp., illus. $49.95. OxfordMedical Publications.Women of Academe. Outsiders in the Sacred Grove.

Nadya Aisenberg and Mona Harrington. University ofMassachusetts Press, Amherst, 1988. xii, 207 pp. $30;paper, $10.95.The Zoogeography of Israel. The Distribution and

Abundance at a Zoogeographical Crossroad. Y. Yom-Tov and E. Tchernov, Eds. Junk, Dordrecht, 1988 (U.S.distributor, Kluwer, Norwell, MA). x, 600 pp., illus.$182. Monographiae Biologicae, vol. 62.

6io

POSITIONS WANTED

Inununologist, Ph.D. Experienced biotechnologyR&D scientist with experience in hybridomas, monoclo-nal antibodies, cellular immunology, and cancer immu-notherapeutics. Seeks position as supervisor of hybrido-ma/cell culture laboratory in biotechnology or pharma-ceutical laboratory. Box 163, SCIENCE.

Japanese Life Sciences Translations: articles, patents,opposition statements, other documents translated fromJapanese in cell biology, microbiology, mycology, plantpathology, immunology, pharmacology, and relatedfields. 1025 Laurel Street #3, Menlo Park, CA 94025.Telephone: 415-321-6317.

Retrovirologist, Ph.D. AIDS researcher with publica-tions and experience in HIV biology, antiviral agents,and some molecular biology. Seeks research/govern-ment position in Washington, D.C., area. Box 162,SCIENCE.

POSITIONS WANTED

Ph.D. 1981. Background in Organic Chemistry andMicrobiology, hands-on experience with modem instru-mentation techniques of isofation and characterization ofmetabolites, fermentation, enzymology and recombinantDNA technology, seeks industrial position. Box 165,SCIENCE.

Tumor and Cell Biologist, M.D., Ph.D. Experience:Receptor biochemistry, peptide hormones, second mes-sengers, cell differentiation, animal and cell culture mod-els, molecular biology. Thirty publications. Seeking staff/faculty position in academia or industry. Box 160,SCIENCE.

POSITIONS OPEN

AERONAUTICAL ENGINEER. Require Ph.D. inaeronautics and 5 years of experience or 5 years ofexperience as researcher and teacher in aeronautical engi-neering. To conduct research in fluid dynamics withemphasis on computational fluid dynamics, grid genera-tion, aeroclasticity and structural dynamics. Full-timeposition. $45,000 per year. Please send resumes to: Ms.Judy Staudinger, G-8-1, Science Applications Inter-national Corporation, 1710 Goodridge Drive,McLean, VA 22102.

ALL NATIONAL OPENINGSMULTIPLE LEVELS

Recruiting for degreed professionals in the followingfields:

1) Pharmacokinetics-industrial or postdoctorate.Pre-cinical and clinical. Up to $65,000.

2) Pharmaceutical formulation scientists-solid andparenteral. Up to $60,000.

3) Clinical researchers and auditors-cardiovascular,infectious disease, and CNS drugs.

Call or send resume to:

Guy AndrewCentral Clearing, Inc.

10031 West Roosevelt RoadWestchester, IL 60153

Telephone: 312450-2660

ANALYT1CAL CHEMISTRY. ThNURE-TRACKFACULTY POSITION at the Department of Chemis-try, San Diego State University. Applications are beingaccepted for a tenure-track position as assistant professorin analytical chemistry beginning fall 1989. Establishedand funded individuals will also be considered for ap-pointment at a senior level. The successful candidate willhave a Ph.D. in analytical chemistry and postdoctoralexperience. We are particularly interested in individualswhose research complements that of existing faculty andwhich emphasizes electrochemistry or spectroelectroche-mistry. The successful applicant will be expected todevelop a vigorous independent research program, su-

pervise Ph.D. and M.S. students, and participate in thegraduate and undergraduate teaching programs. Applica-tions, including curriculum vitae, list of publications,summary of past accomplishments, a detailed plan offuture research, and three letters of recommendation,should be sent to: The Search Committee Chair,Department of Chemistry, San Diego State Universi-ty, San Diego, CA 92182 by 15 December 1988. SanDiego State University is an Affirmative Action/Equal Op-portunity Title IX Employer, and encourages applicationsfrom women and minorities.

ANATOMIST-The Department of BiologicalAnthropology and Anatomy, Duke University, invitesapplications for a tenure-track position beginning 1

August 1989. The level of the appointment will dependon the qualifications of the successful candidate, who willbe expected to participate in teaching medical grossanatomy, contribute to graduate teaching, and conductan active program of research into the morphology,behavior, adaptations, or evolution of primates or othermammals. Completed Ph.D. and prior experience inteaching gross anatomy are desirable. Send curriculumvitae and a list of three references by 31 December 1988to: Search Committee, Department of BiologicalAnthropology and Anatomy, Box 3170, Duke Uni-versity Medical Center, Durham, NC 27710.

Duke University is an Equal Opportunity/Affirmative Ac-tion Employer.

SCIENCE, VOL. 242

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence. SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

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POSITIONS OPEN

ASSISTANT PROFESSOR: Applicants are beingsolicited for two tenure-track positions. The appointeeshould have at least 2 years of postdoctoral experienceand proven research potential in cell biology, neurobiolo-gy, or developmental biology. Excellent facilities forresearch are available including start-up funds and intra-mural grants. Submit curriculum vitae, brief statement ofresearc and references to: Dr. Leonard Seelig, De-partment of Anatomy, LSU Medical Center, P.O.Box 33932, Shreveport, LA 71130. An Equal Opportu-nity Employer.

ASSISTANT PROFESSORThe Department of Chemistry, Philadelphia College

of Pharmacy and Science, invites applications for a full-time, tenure-track faculty position at the assistant profes-sor level, starting August 1989. We seek a candidate whowill establish a vigorous, productive research programand who will excel at teaching in both our undergraduateand graduate programs. Applicants in the areas of bio-chemistry or molecular biology are preferred, althoughexceptional candidates from other areas of chemistry willalso considered.The Philadelphia College of Pharmacy and Science is

an independent, co-educational institution with 1500undergraduate science majors in eight disciplines, 120full-time faculty, and 60 graduate students. The Depart-ment of Chemistry has 14 faculty members and offersACS approved undergraduate degrees in chemistry andbiochemistry. Graduate programs lead to the M.S. andPh.D. degrees in medicinal chemistry and pharmacogno-sv, and may involve interdisciplinary research with theDepartments of Biology, Pharmacology and Toxicology,and Pharmaceutics.

Applications should consist ofcurriculum vitae, a briefstatement of teaching experience and interests, and adescription of research projects that would be pursued, aswell as start-up requirements. Applicants should alsoarrange to have undergraduate and graduate transcripts,and three letters ofrecommendation, sent by 15 Novem-ber 1988 to:

Dr. Peter CampbellChair, Faculty Search Committee

Philadelphia College of Pharmacy and ScienceiifiooWLad Avenue at 43rd Street

Philadelphia, PA 19104Telephone: 215-596-8839

Equal Opportunity/Affirmative Action Employer

ASSISTANT PROFESSOR-BIOCHEMISTRY.The Department of Chemistry at the University ofDenver invites applicants for a tenure-track positionbeginning September 1989. The successful applicant willbe expected to show a strong commitment to teachingand develop a productive, externally-funded researchprogram. Teaching duties will be primarily in the area ofbiochemistry at both the undergraduate and graduatelevels, but may indude lower division undergraduatecourses. The Department of Chemistry offers an ACSapproved undergraduate degree as well as M.S. andPh.D. degrees. Applicants should send curriculum vitae,a brief description of research interests, and arrange tohave three letters of recommendation sent to: Dr. Shel-don S. York, Search Committee Chair, Departmentof Cheniistry, University of Denver, Denver, CO80208 by 1 December 1988. 7he University ofDenver isan Affimative Action institution.

Grinnell College. Tenure-track position as ASSIST-ANT PROFESSOR OF BIOLOGY beginning Au-gust 1989 in population and evolutionary biology, withproficiency in quantitative methods of the disciplme anda commitment to field research. Teach advanced coursein candidate's specialty with extensive use of field stationand laboratory, sophomore course in population andevolutionary biology for majors, one semester of team-taught lecture-laboratory course in introductory biology,and supervise student research. Seeking candidates withpostdoctoral research experience who plan active re-search programs for undergraduates. Start-up funds,excellent facilities, continuing support for research. Sendcurriculum vitae, three letters of recommendation andcopies of transcripts to: Bruce A. Voyles, Chair, De-partment of Biology, Grinnell, IA 50112-0806. Ap-plication deadline: 15 January 1989. Grinnell College is anAfirmative Action/Equal Opportunity Employer and especiallyseeks women and minority candidates.

28 OCTOBER I988

ASSISTANT PROFESSOR-The Department ofAnatomy is seeking applications for a tenure-track assist-ant professor position with teaching in either embryolo-gy or gross anatomy. A strong research program isessential. Research area is open, although preference willbe given to candidates utilizing cellular or molecularapproaches. Ph.D., M.D./Ph.D. oreqvalent degrees, atleast 2 years of postdoctoral research, and a funded orfundable research program are required. Rank and salarvare negotiable depending on experience. Position avail-able 1 July 1989. Submit curriculum vitae and names ofthree references by 15 January 1989 to: Dr. Richard E.Harlan, Department of Anatomy, Tulane MedicalSchool, 1430 Tulane Avenue, New Orleans, LA70112. Tulane is an Equal Opportunity/Affinnative ActionEmployer. Applicationsfrom qualified women and minorities areencouraged.

ASSISTANT PROFESSOR: Tenure-track positionin pharmacology. Responsibilities include teaching med-ica, dental, alied health and graduate students, andconducting independent, externally fundable research,preferably in neuro/endocrine pharmacology, using cellu-lar/molecular approaches. Qualifications: Ph.D. in phar-macology or the M.D. degree and 1 to 2 years ofpostdoctoral training and research experience. Applica-tions accepted until position is filled. Send cumculumvitae, detailed description of academic oals, three re-prints, and names of three references to: )?harmacologySearch Committee, Room 753 BMSB, University ofOklahoma College ofMedicine, Oklahoma City, OK73190. The University ofOklahoma is an Equal Opportuni-ty/Affirmative Action Employer.

ASSISTANT PROFESSORM. D. ANDERSON CANCER CENTER

A position is available immediately to join a laboratoryinvestigating immunotoxins directed to human tumors.Applicants should have a recent Ph.D. in molecularbiology with a strong background in recombinant DNAtechnology. Experience in immunoglobulin gene molec-ular biology is preferred. Projects will focus on develop-ment of recombinant antibodies and immunotoxins.Send curriculum vitae, thesis abstract, and names andaddresses of three references to: Dr. Jack A. Roth, M.D. Anderson Hospital and Tumor Institutc, Box 109,1515 Holcombe Boulevard, Houston, TX 77030. AnEqual Opportunity/Afirmative Action Employer.

ASSISTANT PROFESSORMOLECULAR-CELL VIROLOGY

The Department of Microbiology and the College ofMedicine at the University of Iliiois, Urbana-Cham-paign, seeks candidates for a full-time tenure-track facultyposition at the assistant professor level. Starting date isAugust 1989. Applicants should have a Ph.D. or M.D.degree, postdoctoral experience, and show exceptionalpromise to develop an active research program in virolo-gy that preferably focuses on virus structure, the molecu-Ear or cellular biology of viral infection, or the applicationof viruses to study molecular genetics, cell biology and/ordevelopment. Responsibilities will include teaching med-ical and graduate students. Salary commensurate withqualifications.The University of Illinois at Urbana-Champaign offers

outstanding research facilities that include state-of-the-art facilities for molecular engineering, hybridoma pro-duction, flow cytometry, electron microscopy, x-ray crys-tallography and computer analyses. There are extensiveopportunities for interdepartmental interactions in bothmicrobial and eukaryotic cell and molecular biology,virology, immunology, biochemistry, and biophysics.

Applicants should submit curriculum vitae, statementof research interests, and the names of three referencesto:

Je£frey F. GardnerDepartment of Microbiology

University of Illinois131 Burrill Hall

407 South Goodwin AvenueUrbana, IL 61801

Telephone: 217-333-1736To ensure filll consideration applications should be

received by 15 January 1989. Interviews may be con-ducted prior to 15 January 1989 but all applicationsreceived by that date will be given fiull consideration.The University of Illinois is an Affirmative Action/Equal

Opportunity Employer.

ASSISTANT PROFESSORDEPARTMENT OF BIOCHEMISTRYAND MOLECULAR BIOLOGY

Search reopened. Applications are invited for a tenure-track position at the assistant professor level. Applicantsshould have two or more years of postdoctoral experi-ence and should have the potential for establishing anindependent research program in biochemistry and mo-lecu]7ar biology. Interest and excellence in teaching andresearch are expected. The Medical Center includes theSchools of Dentistry, Medicine, Nursing, and GraduateStudies. The Department has Biotechnology and TissueCulture Support Units. Competitive start-up and equip-ment funds will be provided. The present Departmentconsists of 14 faculty with $1.5 million in annual re-search grant support. Interested individuals should sendcurriculum vitae with bibliography, short (three page)summary of planned research, and the names and ad-dresses of three references to the following:

Robert Roskoski, Jr.Head, Department of Biochemistry and

Molecular BiologyLouisiana State University Medical Center

1100 Florida AvenueNew Orleans, LA 70119-2799

LSUMC is an Equal Employment Opportunity/Affirmative Action Employer.

ASSISTANT PROFESSOR-MARINE BIOLO-GY: Tenure-track position beginning September 1989.Specialty to be physiological ecology or biomechanics ofmarine organisms. Responsibilities include developing astrong research program, participation in an introduc-

biolog course, teaching a course in marine biologyandan advanced course based on one's specialty. Post-

doctoral experience preferred. Please send curriculumvitae, statement of teaching and research interests, andthree letters of reference to: Dr. John Howland, Biolo-gy Department, Bowdoin College, Brunswick, ME04011 by 1 December 1988. Bowdoin College is committedto Equal Opportunity through Afirmative Action.

ASSISTANT PROFESSORPROKARYOTE MOLECULAR BIOLOGY

UNIVERSITY OF ILLINOISCOLLEGE OF MEDICINE IN CHICAGOThe Department ofMicrobiology and Immunology at

the University of Illinois College ofMedicine in Chicagois seeking to fill a position at the level of assistantprofessor (tenure-track; associate professor candidateswill also be considered) in prokaryotic molecular biolo-gy, broadly defined. Candidates involved in proteinengineering would be particularly welcome. Candidateswill be expected to develop a strong independent re-search program with external funding. Adequate spaceand start-up funds are available. Participation m teachingand graduate student training is expected.

Applicants should provide the search committee withcurnculum vitae, at least three letters of recommenda-tion, and a briefstatement offuture research interests andplans. The first series of candidates will be consideredafter 1 November 1988 and applications will be accepteduntil the position is filled. Starting date can be Septem-ber, 1989 or thereafter.Send applications to: Drs. A. M. Chakrabarty, Philip

Matsumura, Simon Silver, and Karl Volz, ProkaryoteMolecular Biology Search Comiittee, Department ofMicrobiology andImmunology, University of IllinoisCollege of Medicine at Chicago, P.O. Box 6998,Chicago, IL 60680.

The University of Illinois is an Afirinative Action/EqualOpportunity Employer.

ASSISTANT PROFESSORQUANTITATIVE ECOLOGIST

The Zoology Department at the University ofManito-ba has a tenure-track position starting July 1989. Salaryis dependent on qualifications and experience. A Ph.D.and postdoctoral experience in population dynamics andmodeling is required and responsibilities include teach-ing and research. Applicants must submit curriculumvitae, description ofresearch interests, and representativereprints by 15 January 1989 to: Dr. J. H. Gee, ZoologyDcartment, University of Manitoba, Wimnipeg,

., Canada R3T 2N2. Both men and women are encour-aged to apply. In accordance with Canadian Immigrationrequirements, priority will be given to Canadian citizens andpermanent residents.

PERSONNEL PLACEMENT 611

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

ASSISTANT PROFESSORVERTEBRATE BIOLOGY

The Department ofEcology and Evolutionary Biologat the Umversity of Connecticut invites applications foran anticipated tenure-track faculty position at the assist-ant professor level. A Ph.D. is required, with postdoctor-al experience preferred. The successful candidate will beexpected to establish an active research program infunctional morphology, vertebrate biomechanics, or de-velopmental aspects of morphological evolution. Re-search interests should complement those of currentfaculty in ecology, behavior, physiology, genetics, andsystematics of vertebrates. Teaching responsibilities in-clude comparative vertebrate anatomy, mammalogy, andintroductory biology. Send curriculum vitae, reprints,statement of research plans and teaching interests, andnames offour references by 1 January 1989 to: Dr. T. L.Taigen, Vertebrate Biologist Search Committee, De-partment of Ecolog and Evolutionary Biology, U-42, University of Connecticut, Storrs, CT 06268.Affirmative Action/Equal Opportunity Employer.

THE UNIVERSITY OFBRITISH COLUMBIA

DEPARTMENT OF CHEMISTRYASSISTANT PROFESSORSHIP

The Department of Chemistry, University of BritishColumbia, invites applications for a tenure-track assistantprofessorship in organic chemistry, starting 1 July 1989.Preference will be given to candidates in biologicalchemistry or physicai or anic chemistry; however, out-standing candldates in related areas of organic chemistrywill be considered. A Ph.D. and postdoctoral experienceis required. The salary will be commensurate with educa-tion and experience.

The University ofBritish Columbia ofers Equal Opportuni-tyfor Employment to qualifiedfemale and male applicants. Theposition is subject tofinal budgetary approval and, in accordancewith Canadian immigration requirements, priority will be givento Canadian citizens and permanent residents.

Applications consisting of curriculum vitae, list ofpubltions, summary of research interests, a detailedresearch proposal, and the names and addresses of at leastthree references should be sent to:

Larry WeilerProfessor and Head

Department of ChemistryUniversity of British Columbia

2036 Main MallVancouver, British Columbia, Canada

V6T 1Y6Closing date for applications will be 15 January 1989.

ASSISTANT PROFESSORSCELL BIOLOGY

The Division of Structural and Systems Biology,School of Basic Life Sciences at the University ofMissou-ri-Kansas City, is seeking to fill several tenure-trackpositions at the assistant professor level.The successful candidate will be expected to develoo an

independent research program focused in the area of cellbiology. Preferred research areas include regulation ofcell growth, cell differentiation, subcellular organization,and molecular and cellular aspects of neuroscience.The successful candidate should have (i) at least 2 years

of postdoctoral experience, (ii) demonstrated potentialfor or a proven record of extramural funding, and (iii)publications.The Division has responsibilities in graduate studies

and research within the School of Basic Life Sciences,which includes molecular and cellular biology and neuro-sciences and teaching anatomy and physiology in theprofessional health science schools of the University.Send curriculum vitae, including statement of research

and career goals, current or proposed research funding,and the names of at least three references to:

Dr. James D. Yarbrough, HeadDivision of Structural and Systems Biology

School of Basic Life SciencesUniversity of Missouri-Kansas City

2411 HolmesKansas City, MO 64108-2792

Screening of applicants will begin 15 December 1988and continue until all positions are filled.

UMKC is an Equal Opportunity/AffirmativeAction Employer.

Middlebury College-Applications are solicited for aregular appointment (tenure-track) at the rank of AS-SISTANT PROFESSOR (Ph.D.) or INSTRUCTOR(A.B.D.) from chemists or biochemists with back-grounds and interests in experimental physical, physical/analytical, or biophysical chemistry. Secondary interest inenvironmental chemistry would be particularly attractive.Candidates with postdoctoral or grief teaching experi-ence will be given preferential consideration. The suc-cessful candidate should be commnitted to teaching at theundergraduate level and developing a productive re-search program that will significantly invo1ve undergrad-uates. Please submit three current letters of reference thatspeak to experience as a dassroom teacher and potentialfor developmg a research program, an up-to-date resu-me, graduate and undergraduate transcripts, and a de-scription of research interests to: R. W. Gfeason, Chair-man, Department of Chemistry and BiochemistryMiddlebury College, Middlebury, VT 05753. Appli-cation deadline is 13 December 1988. Middlebury Collegeis an Equal Opportunity Employer.

ASSISTANT/ASSOCIATE PROFESSORTULANE MEDICAL SCHOOL

The Department of Microbiology and Immunologyinvites applications from cellular andor molecular immu-nologists for a tenure-track position at the assistant orassociate professor level. Minimum requirements for theposition include a Ph.D. or M.D. and no less than 2 yearsof postdoctoral experience. Establishment ofan indepen-dent research program funded by extramural support isexpected, as is participation in the education of bothmedical and graduate students. All major disciplines arerepresented within the Department, and unique oppor-tunities exist for collaborative and interdisciplinary re-search. Applications from women and ethnic minorities arestrongly encouraged. It is expected that the position will befilled on or before 1 July 1989. To apply, send curricu-lum vitae, a briefoverview ofpresent and future researchdirections, and the names, addresses, and telephonenumbers of three references by 1 December 1988, to:Dr. Judith Domer, Chairman, Search Committee,Department of Microbiolo and Immunology, Tu-lane University School ofPMedicine, 1430 TulaneAvenue, New Orleans, LA 70112. Tulane University isan Equal Opportunity/Affirmative Action Employer.

YALE UNIVERSITYASSISTANT OR ASSOCIATE PROFESSOROF NEUROLOGY (NEUROSCIENCE)

The Department of Neurology at the Yale School ofMedicine seeks outstanding candidates with a Ph.D. orM.D. and with at least 2 years of postdoctoral trainingand experience (pr^ferably in cellular or molecular neuro-science or related disciplines) to establish a researchprogram on molecular or developmental neurobiology.The position will include teaching of medical students,graduate students, and postdoctoral fellows. Especiallyfavorable opportunities exist in the areas of molecularbiology or biochemical pharmacology of ion channelsand receptors, synaptic structure-funcuon, cell-cell recog-nition, membrane structure-function, developmental neu-robiology, and neurogenetics. Excellent facilities and sup-port are available. Joint appointment may be arranged orappropriate candidate in basic science department.Send curriculum vitae and names of three references by

1 December 1988 to: Jeffery D. Kocsis, Ph.D., Chair-man, Neurology Search Committee, Department ofNeurology, LCT 702, Yale Medical School, 333 Ce-dar Street, New Haven, CT 06510. An Equal Opportu-nity/Affirmative Action Employer.

BIOCHEMISTUniversity in Philadelphia, Pennsylvania has a job

opening for biochemist to join a research group studyingmolecular and/or cell biological interactions of bloodcoagulation. Applicant should have a Ph.D. in biochem-istry with at least 3 years of postdoctoral experience inmolecular or cell biology and cell culture. Familiaritywith recombinant DNA techniques is desireable. A non-tenured faculty position with fuil benefits and the rank ofresearch assistant professor is available. Salary: $35,000per year, full-time. Submit resume or curriculum vitae to:The PhiLadelphia Job Bank, 444 North 3rd Street,3rd Floor, hiladelphia, PA 19123; refer to JobOrder #4208509.

ASSISTANT/ASSOCIATE PROFESSOR. TheDepartment of Microbiology and Immunology of theUniversity of Michigan Medical School seeks an immu-nobiologist for a tenure-track appointment as assistant/associate professor. The successful applicant will establishan independent research program applying modem mo-lecular/cell biological approaches to the study of theimmune response. The position requires active participa-don in teaching of graduate and medical students. Salarysupport, a well-equipped laboratory and start-up fundsare available from departmental resources. Send curricu-lum vitae, a brief statement of research interests andnames and addresses of three referees by 30 December1988 to:

Immunology Search Chairmanof Microbiology and Immunology

The University of Michigan Medical SchooFM6643/0620 Medical Science Building II

Ann Arbor, MI 48109-0620The University of Michigan is an Equal Opportunityl

Affirmative Action Employer.BIOCHEMIST. Old Dominion University, Depart-

ment of Chemical Sciences announces a tenure-trackopening at the assistant professor level. A Ph.D. inchemistry or biochemistry is required, and postdoctoralexperience is preferred.A research interest in the area of biochemistry or

clinical chemistry is expected. The successful candidatewill teach in the graduate and undergraduate programs ina Ph.D. granting department. The candidate is expectedto establish an active research program and seek externalfundin.

Qualified persons should submit their curriculum vi-tae, a description of their proposed research interests,and have three letters ofrecommendation sent to: Dr. R.L. Williams, Biochemistry Search Comnmittee, De-partment of Chemical Sciences, Norfolk, VA 23529--126. The deadline for applications is 30 November1988. Old Dominion University is an Equal Opportunity!Affirmative Action Employer; and minorities and women areespecially encouraged to apply. Compliance with the Immigra-tion Reform and Control Act of 1986 is required.

The Department of Chemistry at the University ofMaryland Baltimore County invites applications andnominations for a tenure-track position m BIOCHEM-ISTRY at the ASSISTANT PROFESSOR level. Ap-plicants in all areas of biochemistry will be consideredwho have the potential to develop an exceptionallystrong experimental research program. The successfulapplicant may participate in the departmental Ph.D.programs in chemistry, biochemistry, and molecular andcell biology. Send curriculum vitae, statement of researchplans, and three letters of recommendation to: SearchCommittee, Department of Chemistry, University ofMaryland Baltimore County, Baltimore, MD 21228.UMBC is an Equal Opportunity/Affirmative Action Employ-er, and applications from qualified women and minority areespecially encouraged. Applications will be received until asuitable candidate is found.

BIOCHEMISTRY-UNIVERSITY OF IOWA

The Department of Biochemistry in the College ofMedicine ofthe University ofIowa seeks highly qualifiedapplicants for faculty positions at the ASSOCIATEAND FULL PROFESSOR levels. Salaries are competi-tive and will depend on qualifications and experience.Support for equipping laboratories will be excellent.Applicants with research in any area ofmodern biochem-istry will be considered. Quality ofresearch, not a specificresearch area, will be the primary criterion.

All applicants must have a relevant graduate degree[Ph.D., M.D. (or both) or equivalent foreign degree], awell-funded on-going research program and significantnational stature in their research area. In addition tocontinuing successful research programs, faculty partici-pate in the department teaching programs. The trainingof graduate students and participation in appropriategraduate programs also is expected.

Applications, including a complete curriculum vitae, abrief description of current and future research, and thenames of at least three references; or nominations, shouldbe sent to: Alan G. Goodridge, Professor and Head,Department of Biochemistry, College of Medicine,University of Iowa, Iowa City, IA 52242. The Univer-sity of Iowa is an Aflfirmative Action/Equal OpportunityEmployer.

SCIENCE, VOL. 2426I2

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

BIOCHEMISTA small Midwest manufacturer of specialty ingredients

for the animal feed indust seeks a biochemist to join itstechnical service group. The position involves travelingwith the company's sales force to affect technical trainingin the field, and to meet with prospective clients concern-ing use of the company's products in animal feed. Theindividual will also be charged with the responsibility ofcoordinating field experiments with various universitiesand writing of technical/sales bulletins. This positioninvolves 70% travel in the United States and abroad. Thesuccessful candidate will possess excellent verbal andwritten communication skills and enjoy communicatingscience to the feed industry. The position requires aPh.D. in biochemistry or related field. An excellentcompensation package is offered.

Interested parties should submit their resumn to: JedHarms, Executive Director of Sales and Marketing,Kemin Industries, Inc., P.O. Box 70, Des Moines, IA50301.

An Equal Opportunity Employer.BIOCHEMISTRY FACULTY POSITION. Full-

time tenure-track teaching and research position in theDepartment of Physiological Chemistry, College ofMedicine. Candidates should hold a Ph.D. or M.D., havea minimum of 2 vears of postdoctoral research experi-ence, and show clear potential to sustain a viable, inde-pendent research program. Send curriculum vitae, namesof three references, and a statement of research plans to:Search Committee, Department of PhysiologicalChemistry, 5166 Graves Hall, The Ohio State uni-versity, Columbus, OH 43210. Applications should bereceived by 31 December 1988. OSU is an Equal Opportu-nity/Affirmative Action Employer, and we encouirage applica-tionsfrom women and minority candidates.

BIOLOGIST: The Biology Department of WilliamJewell College invites applications for a tenure-trackassistant/associate professorship in biology beginning fall1989. The candidate should have a Ph.D. in physiologywith postdoctoral experience preferred. Address letters ofapplication by 21 November 1988 to: Dr. Judith A.Dilts, Chair, Department of Biology, William JewellCollege, Liberty, MO 64068. Telephone: 816-781-7700, X5661. WilliamJewell is an Affirmative Action/EqualOpportunity Employer and specifically encourages applicationsfrom minorities and women.

BIOMEDICAL DIAGNOSTICSPB Diagnostic Svstems, Inc. (PBDS) is a new entry in

the field of biomedical diagnostic instrumentation sys-tems. Founded jointly by Behringwerke AG, and Polar-oid Corporation, PBDS is a securelv funded venturededicated to bringing significant, novel products to themarket place. As the company continues to grow andexpand, there are opportunities available for experiencedpeople to work in a very special start-up enviroument inthe Boston area.

SCIENTIST, INFECTIOUS DISEASESYou will be responsible for the development of sero-

logical assays for the detection of antibodies to variousviral agents. These assays will be based on a noveltechnique developed by PBDS. Supervision of assistantscientists and technicians, documentation, and technolo-gy transfer will be functions of the position.The successful candidate will hold a Ph.D. degree in

microbiology, biochemistry, or immunology with 3 to 5years of experience in assay development from researchstages through transfer to manufacturing. Experiencewith infectious disease serology assays such as HIV,Rubella, or other TORCH agents is highly desirable.

SCIENTIST, IMMUNOASSAYYou will be responsible for development of nonisoto-

pic immunodiagnostic reagents including antibody puri-fcation, conjugation, assay optimization, correlationcross-reactivity, precision, stability and interference stud-ies. Additional duties will include supervision of labora-tory staff, and interface with external groups responsiblefor 510(k) approval, manufacturing, and quality control.The successful candidate will have a Ph.D. or M.S. in a

chemistry-related area with a minimum of 3 years ofexperience in irmunodiagnostics research and develop-ment, including supervisory experience. Demonstratedsuccessful product evelopment leading to FDA approv-al is required. Please send curriculum vitae to: HlumanResources, PB Diagnostic Systems, Inc., 151 Univer-sity Avenue, Westwood, MA 02090.

OCTOBER I988

DEPUTY DIVISION_LEADERSThe Life Sciences Division at the Los Alamos National Laboratory hasopenings for two Deputy Division Leaders. The individuals will beresponsible for assisting the Division Leader with leading, developing andcoordinating the Division's multidisciplinary research projects in physiol-ogy, biochemistry, biophysics, cellular and molecular genetics, and cellbiology and with the administrative management of the Division. Thesuccessful candidates will support strong interactions and collaborationswith academia and private industry. One Deputy Division Leader will beresponsible for financial and personnel management and for extensiveinteraction with sponsoring agencies including DOE, DOD, NIH and theprivate sector. The second Deputy Division Leader will be responsible forresearch planning including responsibility for the field of chromosomestructure and function.

The successful candidates must have a PhD or equivalent in molecularbiology, genetics, biophysics or other related sciences. A strong researchrecord in fields relevant to LS Division research activities is required.Demonstrated successful program development and managementexperience are desirable.

To apply, submit detailed curriculum vitae to: Richard 0. Garcia (MSP280), Personnel Services Division 80556-CH, Los Alamos NationalLaboratory, Los Alamos, NM 87545.

Affirmative Action/Equal Opportunity EmployerU.S. Citizenship Required

University of California

©$ L0

PlantPhysiology!BiochemistryDeKalb-PflzerGenelcs

An equal opportunityemployer

Plant Genetics Research at Pfizer Central Research,in conjunction with plant breeding stations worldwide,conducts research and development for DeKalb-Pfizer Genetics, a leading agricultural seed company.We invite applications from PhD-level scientists tojoin our multidisciplinary research team focused onthe genetic improvement of corn. You must be an ac-complished scientist who has innovative researchapproaches and is able to work effectively as part ofan established research team.You will join a research group investigating the phys-iological and biochemical basis for superior agro-nomic performance of corn. The short-term goals ofthis program are to identify germplasm sources forimportant agronomic traits and to develop methodo-logy for following these traits in segregating popula-tions. Longer term objectives include understandingthe biochemical and molecular basis of superioragronomic performance with the potential for gene-tically manipulating these traits. Existing programsinclude investigating the response of corn to envi-ronmental stresses. All work would closely integratewith our cell biology, tissue culture and molecularbiology teams involved with the transformation andgenetic manipulation of corn. If you have experiencein plant physiology, biochemistry and genetics, youare encouraged to apply.This position provides excellent opportunities for pro-fessional recognition and growth. We offer an ex-cellent salary, benefit and relocation package plusan attractive southeastern Connecticut shore loca-tion. Please send resume and description ofresearch accomplishments to: Dr. Jerry K. Larson,Manager of Employment, Pfizer Central Research,Eastern Point Road, Groton, CT 06340.

.M

m

-

POSITIONS OPEN

BIOCHEMISTRY-UNIVERSITY OF IOWA

The Department of Biochemistrv in the College ofMedicine of the University ofIowa seeks highly qualifiedapplicants for faculty positions at the ASSISTANTPROFESSOR (tenure-track) level. Salaries are competi-tive; support for equipping laboratories and initiatingresearch programs will be excellent. Applicants withresearch in any area of modern biochemistry will beconsidered, but preference will be given to applicantswhose research interests involve the structure, uctionand dynamics of macromolecules and membranes. In thefinal analysis, however, quality of research, not a specificresearch area, wil be the primary criterion.

All applicants must have a relevant graduate degree[Ph.D., M.D. (or both) or equivalent foreign degree], atleast 2 years of productive postdoctoral experience, andthe potential to mnitiate and maintain a vigorous researchprogram. In addition to establishing successful researchprograms, faculty participate in the department teachingprograms. The training of graduate students and partici-pation in appropriate graduate programs also is expected.

Applications, including a complete curriculum vitaeand a brief description ofcurrent and future research; ornominations, should be sent to: Alan G. Goodridge,Professor and Head, Department of Biochemistry,College of Medicine, University of Iowa, IowaCity, IA 52242. Candidates should arrange to havethree letters of reference sent to the same addressee. TheUniversity ofIowa is an Affirmative Action/Equal OpportunityEmployer.

BIOLOGY: Two tenure-track positions at ASSIST-ANT PROFESSOR rank, Berca College, to beginSeptember 1989. Ph.D. required, along with demon-strated commitment to undergraduate teaching and abili-ty to involve students in research. Cell physiology andmolecular biology: Teach advanced courses in cell physi-ology and genetics, and other courses for majors andnonmajors. Anatomy and physiology: Teach humananatomy and physiology, advanced physiology, and oth-er courses for majors and nonmajors. In keeping with theCollege's Christian tradition and its emphasis on the worth anddignity ofall persons, Berea encourages applicationsfrom womenand members of minority groups. Submit letter of applica-tion, curriculum vitae, and supporting materials by 15December 1988 to: Dr. Ralph Thompson, BiologyDepartment, Berea College, Bere KY40404.

BIOLOGY: Vertebrate Biology. Search Reopened.Cumberland College, a private, church-related liberal artscollege, invites applications for a TENURE-TRACKPOSMON to begin in August 1989. Courses taughtwill include comparative vertebrate anatomy, vertebratefield biology, comparative physiology, human anatomyand physiology, and general biology. Ph.D. required.Send letter of application, curriculum vitae, copies oftranscripts, statement of teaching philosophv, and threeletters of reference to: Dr. Joseph E. Early, AcademicDean, Cumberland College, Williamsburg, KY40769. Deadline: January 1989.

CANCER/CELL BIOLOGY POSITIONAT THE UNIVERSITY OF ARIZONA

As part of a University-wide expansion of BiologicalSciences and Biotechnology, the Department of Anato-my and the Arizona Cancer Center at the University ofArizona are seeking a new tenure-track faculty member.Preference will be given to applicants with researchinterests in the areas of cancer cel biology or molecularand genetic studies of development, although outstand-ing candidates in other areas will be considered. Candi-dates should have pertinent postdoctoral experience. Weprefer candidates at the assistant professor level, butmore senior appointments may be made for exceptionalindividuals. Successfuil candidates will be expected toestablish an excellent research program and teach at thegraduate level. Submit curriculum vitae, two copies ofrelevant papers, a detailed description of research goals,and have three supporting letters sent to: Dr. JeffreyTrent, Arizona Cancer Center, University ofArizona,1515 North Campbell, Tucson, AZ 85724. To insureconsideration, applications should be received by 15December 1988; however, applications will be accepteduntil the position is filled. The University of Arizona is anEqual Opportunity/Afirmative Action Employer and applica-tions from females and minority group members are stronglyencouraged.

CELL-MOLECULAR BIOLOGISTApplications are being accepted for an anticipated

tenure-track position, starting Augut 1989, in cel andmolecular biology with emphasis in developmental ge-netics. The successful candidate must demonstrate poten-tial for establishing an extramurally funded researchprogram and should complement departmental strengthsin cell, development or genetics programs. Establishmentof an active graduate program and participation in upperlevel cell/tissue instruction is expected. Candidates musthave a Ph.D. and postdoctoral experience is preferred.Salary commensurate with qualifications and experience.Curriculum vitae, selected reprints, statements of re-search and teaching interest, and names of three refer-ences should be forwarded to: Chairman, Cell BiologySearch Committee, Department of Zoology andPhysiology, Louisiana State University, BatonRouge, LA 70803-1725 (Telephone: 504-388-1132BITNET: ZOOPHYS @ LSUVM). Preference will begiven to applications received by 15 January 1989. LSUis an Equal Opportunity/Affirmative Action Employer.

CELL REPLICATION TECHNOLOGYA NASDAQ listed, R&D company engaged in devel-

opment and commercialization of novel, proprietary cellreplication technologies seeks two outstanding POST-DOCTORAL CANDIDATES tO fill new positions onits research team:CYTOTOXICITY-The successful candidate for this

position will have at least 2 years of experience at aprominent institution developing and conducting toxici-ty tests.LONG-TERM CELL CULTURE-This position

requires extensive experience in bone marrow cell cultureor hematology; experience with progenitor assays andflow-cell cytometry will be a plus.

Successful candidates will have strong records of scien-tific achievement and have displayed a capacity for timelycompletion of projects with a minimum of supervision.The company is currently based in New York City

area. In 1 year, the R&D facility will be divided betweenVermont and San Diego.Compensation is designed to attract the best candi-

dates and will include base salary, incentives, and stockparticipation.Rep y in confidence enclosing curriculum vitae to:

C.W.C. Capital Corporation, 420 Ledxngton Avenue,New York, NY 10170. Telephone: 212-697-2143.

CELLULAR/MOLECULAR IMMUNOLOGISTAn outstanding opportunity is immediately available

for a postdoctoral immunologist to join a multi-discipli-nary research group studying the autoimmunity of insu-lin-dependent diabetes. Generous, long-term supportwill be provided to an individual who demonstratespotential for developing an independent research pro-gram. Tenure-track position; send curriculum vitae,statemcnt of research goals, and names of three refer-ences to: Fredda Ginsberg-Fellner, M.D, Box 1198,The Mount Sinai Medical Center, One Gustave L.Levy Place, New York, NY 10029-6574. An EqualOpportunity Employer.

CHAIR, DEPARTMENT OF ANATOMYMorehouse School of Medicine (MSM) invites appli-

cations for the position of Professor and Chair of theDepartment of Anatomy to begi 1 July 1989. Thecandidate should be a well-estabeshed investigator in acurrent field of research who has demonstrated a strongcommitment to teaching medical students. The applicantshould also have demonstrated academic administrationcapabilities. Applicants must have the Ph.D. or M.D./Ph.D. degree.MSM is an expanding, new, private medical school

with a strong commitment to the academic and scientificgrowth of minority students. The position offers anexcellent opportunity to develop an outstanding, pro-gressive department in an institutionally supported atmo-sphere of cooperative growth and development.

Initial screening of candidates will begin 1 December1988. Applications or letters of interest along withcurriculum vitae, including research, teaching, and ad-ministrative experience should be sent to: Collns Baber,M.D., Chair, Search Committee for the Chairpersonof Department of Anatomy, Morehouse School ofMedicine, 720 Westview Drive, S.W., Atlanta, GA30335.

CELLULAR NEUROPHYSIOLOGIST/ANI-MAL PHYSIOLOGIST. The Department of Biologyat Bryn Mawr College has a tenure-track opening for ahighly qualified young investigator having an activeinterest in both research and teaching. The successfilapplicant will be expected to establish a funded researchprogram and to participate in the undergraduate andgraduate teaching programs of the department and of ananticipated new interdepartmental program in neural andbehavioral sciences. We seek a broadly trained cellularneurobiologist whose program will complement existingstrengths in neuroscience, and who is able to teach bothcellular neurophysiology and animal physiology. Appli-cations, including curriculum vitae, a statement ot re-search and teaching interests, selected reprints, and thenames of three references, should be sent to: Dr. PaulGrobstein, Department of Biology, Bryn Mawr Col-lege, Bryn Mawr, PA 19010. Afirmative Action/EqualOpportunity Employer.

DIRECTOR, DUKE UNIVERSITY MARINELABORATORY. Duke University invites nominationsand applications for the position of Director ofthe DukeUniversity Marine Laboratory (DUML). We seek anindividual with a Ph.D. in a marine or related science, asuperior record of leadership qualities, a record of pro-gram management and proven entrepreneurial skills.Candidates will be evaluated on the basis of their poten-tial to lead the program, attract outstanding faculty, andlead a development program to enhance quality andproductivity. In addition to administrative responsibil-ities the Director is expected to play a major rore in thedevelopment of an emerging university-wide program inocean studies. The Director reports to the UniversityProvost.The Duke University Marine Laboratory is situated on

fifteen acres of Pivers Island, adjacent to the historictown of Beaufort, North Carolina. The facility comprises23 buildings including a library, auditorium, dormi-tories, classroom, cafeteria, and several research buildingsand labs. At present, the permanent research staff atDUML numbers 12 with a support staff of 60.

Interested candidates should send an application letter,curriculum vitae, and the names and addresses of threereferences to: Dr. Ronald D. Perkins, Chairman ofDUML Search Committee, Department of Geoloag,Duke University, Durham, NC 27706. Closing datefor applications iS 15 December 1988. It is hoped thatthe appointment will be made on or before 31 August1989. Duke University is an Equal Opportunity/AffinnativeAction Employer.

BIOCALORIMETRY CENTERThe Biocalorimetry Center, a newly created national

Research Technology Resource Facility, invites applica-tions for the position of DIRECTOR OF OPERA-TIONS. Applicants should have a Ph.D. degree andpostdoctoral experience in the development an or appli-cation of calorimetric techniques in biomedical research.The successful applicant will have a nontenure trackresearch faculty appointment at the assistant professorlevel and is expected to supervise the day-to-day opera-tions of the Center as well as to develop an independent,vigorous research program.

Interested individuals should submit a letter of inten-tion, curriculum vitae, and three letters of reference to:Dr. Ernesto Freire, Department of Biology, TheJohns Hopkdns University, Baltimore, MD 21218.

ELECTRON MICROSCOPIST/CELL BIOLO-GIST-The Grace Cancer Drug Center of Roswell ParkMemorial Institute is seeking a staff member to assumethe responsibilities of the electron microscopy unit.These include (a) establishing an independent scientificprogram in the area of non-erythroid spectrin functionand organization and (b) interacting on a collaborativebasis with other staff members in research problemsrelated to ultrastructural localization of oncogene prod-ucts, anticancer drugs and membrane-associated pro-teins. Applicants should have 1 to 2 years of postdoctoralexperience with expertise in various localization strate-gies, in situ hybridization, protein purification andmonoclonal antibodies. Please send resumeto: Dr. En-rico Mihich, Chairman, Grace Cancer Drag Center,Roswell Park Memorial Institute, Elm And CarltonStreets, Buffalo, NY 14263. An Equal OpportunityEmployer.

SCIENCE, VOL. 2426I4.

POSITIONS OPEN POSITIONS OPEN

THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNOUNCES

The Second

AACR Specil Conferenc in Cancer Research

THE ROLE OF DNA VIRUSES IN HUMAN TUMORS

Supported by a Generous Grant from the General MotorsCancer Research Foundation

January 22-26, 1989Catamuaran Resort Hotel, San Diego, Califomia

PROGRAM COMMITTEE

Jesse W. SummersHara zur Hamme, Cbairman

R. Pahser Beasley

SCIENTIFIC PROGRAM

KEYNOTE ADDRESS (An Anniversary in Vims Reseamhin Human Tumnr)

"Twenty-five Years of Epehin-Barr Vinu Research:Piesent Satae and Perspectives," M. A. Epstein,Oxford, UK

DNA TUMOR VIRUSES: CONCEPTS AND NEWDEVELOPMENTS

R. Dulbecco, La Jolla, CAR. P. Beasley, Houston, TXH. zur Hausen, Heidelberg, FRGR. C. Gallo, Bethesda, MD

VIRAL DNA IN HUMAN TUMORSG. Barbanti-Brodano, Ferraro, ItalyG. Orth, Paris, FranceE-M. de Villiers, Heidelberg, FRGK. Koike, Tokyo, Japan

VIRUS-HOST CELL INTERACTIONS INONCOGENESIS

G. Miller, New Haven, CTF. Wettstein, Los Angeles, CAF. V. Chisari, La Jolla, CAD. Lowy, Bethesda, MD

George Milier

REGULATION OF VIRAL GENE EXPRESSION INLATENTLY INFECTED CELLS

J. Summers, Albuquerque, NME. Kieff, Boston MAA. Sergeant, Lyon, FranceP. Howley, Bethesda, MD

MECHANISMS OF CELL TRANSFORMATION ANDIMMORTALIZATION

L. Laimins, Chicago, ILB. Sugden, Madison, WIE. Schwarz, Heidelberg, FRGP. Tiollais, Paris, France

VIRUSES WITH INITIATOR-LIKE FUNCTIONSAND VIRUSES ACTING AS ANTICARCINOGENS

J. Rommelanre, Brussels, BelgiumR. Heilbronn, Heidelberg, FRG0. Yalkinoglu, Heidelberg, FRGE. Winocours, Rehovot, Israel

IMMUNOLOGICAL CONTROL OF DNA TUMORVIRUS INFECTION AND ONCOGENESIS

G. Klein, Stockholm, SwedenA. Rickinson, Birmingham, UKS. Jablonska, Warsaw, PolandL. Gissmann, Heidelberg, FRG

INFORMATION AND APPLICATION FORMS

American Association for Cancer Research, Inc.530 Walnut Street, 10th Floor

Philadelphia, PA 19106215440-9300

215440-9313 (FAX)

Attendance is limited; applications will be accepted on a first-come, first-served basis.

ADVANCE REGISTRATION ENDS: DECEMBER 5, 1988

Basic ResearchAdvanced Drug Delivery/ Sy/stemsSan Francisco Bay/AreaLiposome Technology, Inc. (LTI), develops andmanufactures innovative liposome based pharma-ceutical products. These products are designed toimprove efficacy, safety and convenience of phar-maceutical products. Our impressive technologi-cal breakthroughs have created exciting opportu-nities in our research headquarters for:

Postdoctoral FellowsImmunochemistryPhD level chemist with proven skills in monoclo-nal antibody technology including purification, en-zymatic fragmentation, chemical modification andconjugation chemistry. Ability to develop sensitiveand reliable research assays designed to assessbinding affinity and specificity is also required.

Protein BlochemistPhD level biochemist with hands-on experience informulating and handling bioactive peptides andproteins. The successful candidate will haveproven ability to set up assays to measurebiological activity of molecules (RIA, ELISA,

bioassay) as well as in-depth understanding ofpeptide/ protein stability issues. A strong back-ground in the basic aspects of protein analytics isa must.

MolecularBlology/VlrologyPhD level cell or molecular biologist with stronginterest in retrovirology and biological/biophar-maceutical orientation. Hands-on experience incell culture (including primary lymphocyte/mon-ocyte lines) as well as in vitro and in vivo infectiv-ity models is essential. Preference will be given tocandidates with experience in assessing activityof antiviral agents.LTI is committed to providing its employees withboth sophisticated facilities and a competitivesalary/benefits package. Postdoctoral positionslast 1-2 years. For immediate consideration,please send your resume, indicating posibon ofinterest, to: LTI, Professional Staffing, Dept. HR/INST, 1050 Hamilton Court, Menlo Park, CA94025. Principals only; please, no phone calls.LTI is an equal opportunity employer.

MEDICAL REVIEWThe Gillette Medical Evaluation Laboratories, adivision of The Gillette Company, has an entrylevel opening in Medical Review to implementCompany Medical/Legal procedures and applica-ble government regulations in order to ensure thedistribution of safe consumer products. Workincludes initiating medical/biological studies,some participation in industrial hygiene projects,and reviewing drug/device claims and adversereaction claims. Ph.D. in Physiology, Pharmacol-ogy, Toxicology or related science is required.Experience in designing toxicological or clinicaltests and evaluating data and a knowledge ofindustrial hygiene is desirable.Gillette Medical Evaluation Laboratories is locat-ed in a new facility, just outside of Washington,D.C., in an area rich in government, private, andacademic scientific laboratories. We offer excel-lent compensation, comprehensive benefits, andrelocation assistance. For consideration, pleasesend a confidential resume to:

Gillette Medical EvaluationLaboratories

401 Professional DriveGaithersburg, MD 20879

(301) 590-1508Equal Opportunity Employer

POSITIONS OPEN

DEVELOPMENTAL BIOLOGISTDIVISION OF BIOLOGY AND MEDICINE

BROWN UNIVERSITYDevelopmental Biologists are invited to apply for a

full-time tenure-track position at the level of assistantprofessor in the Section of Molecular, Cellular, andDevelopmental Biology, commencing in the fall of 1989.We seek an individual who will establish an active,independent research program focussed on basic mecha-nisms of development and who will interact effectivelywith other members of the Graduate Program in Molec-ular Biology, Cell Biology, and Biochemsstry. While weare particularly interested in applicants with researchinterests in mammalian development, final selection willbe for candidates of outstanding ability, regardless of thesystem studied. At least 2 years of postdoctoral experi-ence and potential for excellence in teaching are required.Teaching responsibilities include participation in vradu-ate and undergraduate courses in Developmental Biologyand Embryology. Applications from women and minoritycandidates are encouraged. Send curriculum vitae, recentreprints, summary of research interests, and have threeletters of recommendation forwarded by 15 December1988 to: Dr. John R. Coleman, Division of Biologyand Medicine, Brown University, Providence, RI02912. FAX: 401-863-3700. Brown University is anEqual Opportunity/Afirmative Action Employer.

ENZYMOLOGIST / BIOCHEMIST / X-RAYCRYSTALLOGRAPHY POSTDOCTORAL posi-tion available to join our ongoing research efforts exam-ining the structural basis of enzyme specificity using acombination ofx-ray crystallography, site-directed muta-genesis and kinetics analysis. a-Lytic protease providesan idea model system for examnini an aspects of speci-ficity structure-function relationships. Two Xentronixarea detectors, two diffractometers, two E&S displays,and state-of-the-art computational resources are avail-able. Applicants should send curriculum vitae and namesand addressce of three referees to: Dr. David A. Agard,HHMI Stmctural Biology Unit, Department of Bio-chemistry, UCSF Medical Center, San Francisco, CA94143-0448.

THE UNIVERSITY OF CHICAGOThe Joseph P. Kennedy, Jr. Mental Retardation Re-

search Center and the Department of Pharmacologicaland Physiological Sciences are recruiting new FACUL-TY with research interests related to the molecular andcellular biology of the nervous system. Applicants shouldsend their curriculum vitae and bibliography, a briefstatement of research interests and plans, and the namesof three references to:

Dr. Robert L. Perlman, DirectorKennedy Mental Retardation Research Center

Department of PediatricsThe University of Chicago

5841 South Maryland Avenue, Box 413Chicago, IL 60637

From the time of its original charter, the principle of theUniversity of Chicago has been to appoint scholars withoutregard to race, color, religion, sex, or national origin.

The Eppley Institute for Cancer Research of theUniversity of Nebraska Medical Center invites applica-tions for a FACULTY POSITION (tenure-leading) atthe assistant professor level to strengthen its program inthe molecular biology of cancer. Candidates shouldpossess a Ph.D. or M.D., have several years of postdoc-toral experience, and should be engaged in such researchareas as oncogenic virology, molecular genetics, tissue-specific gene expression, or development of tools forgene therapy. Start-up funds and a competitive salary areavailable. The successful candidate win be expected tocontribute to the academic programs of a department inthe College of Medicine or Pharmacy in which he/shewill hold an appointment. Submit curriculum vitae, aone-page summary of your research interests, and havethree letters of reference forwarded to: Dr. EdwardBresnick, Director, Eppley Institute for Research inCancer and Allied Diseases, University of NebraskaMedical Center, Omaha, NE 68105. The University ofNebraska Medical Center is an Equal Opportunity Employer/Afirmative Action Employer. Please refer to position #8-6158. Closing date: 30 November 1988.

FACULTY POSITION-BIOCHEMISTRYCARLETON COLLEGE

The Department of Biology of Carleton College in-vites applications for a 1-year faculty leave replacement.Teaching responsibilities will include biochemistry andassociated laboratory, cell/molecular physiology, a semi-nar in the candidates research specialty and participationin a team taught introductory course. A Ph.D. is requiredand the appointment will be at the assistant professorlevel. Women and minorities are especially encouraged to apply.Carleton College is an undergraduate institution dedicat-ed to excellence in teaching. The osition begins on 1September 1989. Interested candidates should send cur-riculum vitae, graduate transcripts, and three letters ofrecommendation by 15 January 1989 to: Dr. JohnTymoczko, Department ofBiology, Carleton College,Northfield, MN 55057-4025.

Carletotn College is an Equal Opportunity/Affirmative Ac-tion Employer.

FACULTY POSITION IN CHEMISTRYThe Chemistry Department at the University of Cali-

fornia, Berkeley, solicits applications for positions asassistant professor of chemistry, beginning in the fall1989. We have particular interest in applicants in inor-ganic, analytical, organic, and bio-organic chemistry.Creative and energetic candidates who show exceptionalpromise in research and teaching are sought. Individ-ual(s) selected for this position will be expected toestablish an outstanding research program. Subject tobudgetary approval, exceptional candidates with estab-lished programs may be considered for appointment withtenure as professor or associate professor. Candidatesshould send curriculum vitae, a proposed research pro-gram, and arrange to have three letters of recommenda-tion sent to: Professor Paul A. Bartlett, Chairman,Facult Recruiting Committee, Department ofChemistry, University of California, Berkeley, CA94720. T4he deadline for receipt of applications is 1December 1988. The University of Califomia is an EqualOpportunity/Affirmative Action Employer.

FACULTY POSITIONIN PHARMACOLOGY

UNIVERSITY OF CALIFORNIAIRVINE

Applications are invited for a tenured or tenure-trackfaculty position in pharmacology. We are especiallyinterested in candidates with an active research programin molecular pharmacology and expertise in neurophar-macology, but qualified candidates in other areas will beconsidered. A Ph.D. in pharmacology or related area, oran M.D. is required. Level ofappointment and salary willbe commensurate with achievement and experience. Cur-riculum vitae, references, and a summary of researchinterests should be sent before 31 December 1988 to:

Dr. Larry Stein, ChairmanDepartment of Pharmacology

College of MedicineUniversity of California

Irvine, CA 92717Thie University of Califomia is an Affirmative

Action Employer.

FACULTY POSITION IN POPULATION BI-OLOGY: The University of Illinois at Urbana-Cham-paign invites applications for a full-time tenure-trackposition as an assistant professor in the Department ofEcology, Ethology, and Evolution, starting 21 August1989. Candidates should have strong interests in and anempirical approach to ecological/evolutionary genetics.We are seeking a person who will interact with ourcurrent staff, which includes evolutionary ecologists,evolutionary geneticists, population ecologists, and be-havioral ecologists. A Ph.D. must be earned by thestarting date. Salary commensurate with qualifications.Teaching responsibilities include population biology andother courses in her/his area of expertise. To assure fullconsideration applicants should send curriculum vitae,statement of research and teaching interests, and threeletters ofreference by 15 December 1988 to: Dr. LowellL. Getz, Department of Ecology, Ethology, and Evo-lution, University of Illinois, 515 Morrill Hall, 505South Goodwin Avenue, Urbana, IL 61801. Tele-phone: 217-333-7802. The University of Illinois is anAfirmative Action/Equal Opportunity Employer.

FACULTY POSITIONPLANT MOLECULAR SYSTEMATICS

The Department of Botany, Iowa State University,invites applications for a tenure-track position at theassistant or associate professor level. Preparation fordevelopment of a strong research program applyingmolecular methods to questions of plant systematics andevolution is required. Teaching responsibilities will in-clude a specialty graduate course and participation inundergaduate teaching in biology or botany. Candidatesmust have a Ph.D. or equivalent.

Applications must incLude curriculum vitae, statementsof research interests and teaching philosophy, and re-prints of selected publications. Applications and at leastthree letters of reference should be sent to: Dr. David C.Glenn-Lewin, Chair, Department of Botany, IowaState University, Ames, IA 50011 by 15 December1988.

Women, minorities, and members ofotherprotectedgroups arestrongly encouraged to apply. Iowa State University is an EqualOpportunity/Affirmative Action Employer.

FACULTY POSITIONS IN BIOLOGICALSCIENCES AND SCIENCE EDUCATIONThe Department of Biological Sciences, San Jose State

University, invites applications for four tenure-track po-sitions to begin August 1989. Applicants must haveeamed doctorate and teaching expenience. Postdoctoralresearch experience desired. Signifcant professional con-tributions and development of active research programwill be expected. All positions include teaching generaleducation science, advising undergraduate and/or gradu-ate students and participation in the Master's degreeprogram. The University is especially interested in hiringfaculty members who are aware of and sensitive to theeducational goals and requirements of an ethnically andculturally diverse student population. (i) GENETI-CIST/MOLECULAR BIO7LOGIST. Assistant Profes-sor. Candidate should have a research interest in eukary-otic molecular genetics and will teach an undergraduatecourse in recombinant DNA techniques, an advancedcourse in candidate's specialty, and/or courses in generalgenetics. (ii) TOXICOLOGIST/CELL BIOLOGIST.Assistant Professor. Candidate will teach introductoryand advanced courses in toxicology, course(s) in celbiology for biology majors, and/or introductory biologycourses. (iii, iv) SCIENCE EDUCATOR/BIOLO-GIST. Two positions: one each at the Assistant Professorand Associate Professor levels. Successful applicants willcontribute to the pre-service secondary science teachertraining program, supervise secondary science studentteachers, teach secondary science methods and/or biolog-ical specialty, and maintain biological or educationalresearch program. Prefer experience in secondary scienceteaching and supervision. Completed applications, withtranscripts, curnculum vitae, statement of professionalgoals, and three current letters of reference must be sentby5January 1989 to: Dr. Wayne Savage, Chairman,Deeartment of Biological Sciences, San Jose StateUmiversity, San Jose, CA 95192. SJSU is an EqualOpportunity/Affirmative Acion, Title IX Employer.

FACULTY POSITIONS INMOLECULAR PHARMACOLOGY

The Department of Pharmacology, University of Mis-souri-Columbia (UMC), invites applications or juniorand senior level, tenure-track positions focusing on theapplication ofmolecular biology to analysis of significantproblems in pharmacology. One of the positions (assist-ant professor) is under the auspices o a campus-wideeminence program in molecular biology. Successful can-didates are expected to have a strong record of researchaccomplishments and the potential to develop high quali-ty, independent research programs with long-termgrowth potential. Research areas of interest include butare not fted to: structure, function and regulation ofreceptors, membrane transport proteins, and ion chan-nels; molecular mechanisms of transmembrane signal-ling; and, actions of drugs, neurotransmitters andgrowth factors. Successful candidates also will be expect-ed to participate in the teaching of medical and graduatestudents. Please send curriculum vitae, a briefdescriptionof research plans, and the names of three references to:Dr. Hyun Dju Kim, Professor and Chairman, De-partinent of Pharnacology, University of Missouri-Columbia, School of Medicine, M517B Medical Sci-ences Building, Columbia, MO 65212. An Equal Op-portunity/Affirmative Action Employer.

SCIENCE, VOL. 2426I6

POSITIONS OPEN POSITIONS OPEN

NEW ENGLAND BIOLABS

Postdoctoral PositionsNew England Biolabs, a pioneer and leader in biotechnology.located twenty miles north of Boston, is seeking applicaints forpostdoctoral positions.

Nucleic Acid Enzymologist-To study endonuclease/D)NA in-teractions. Candidate should have training in biochemistry/ell-zymology and/or molecular biology. Experience with over-

production and mutagenesis of proteins in bacterial systemswould be helpful.

Molecular Genetics-Candidate should have strongbackground in molecular biology or bacterial genetics to studythe interaction between restriction modification systems and

the host cell. Knowledge of protein chemistry would be helpful.

Immunologist/Parasitologist-To study the cellular immuneresponse to recombinant filarial antigens (MolecularParasitology Division).

In addition to competitive salary, New England Biolabs offersa very generous fringe benefits package. Attendanceeatmeetings, publication of research results and open communica-tion with others are encouraged.

Candidates please submit curriculum vitae with three referencesto:

New England Biolabs, Inc.Human Resources32 Tozer RoadBeverly, MA 01915-5510 NEW ENGLAND

I

I I Postdoctoral Research AssociateshipsGraduate Assistantships

Michigan State University has received funding toestablish a Plant Science Center under a programsponsored by USDA, NSF and DOE. Several positionsare available in four established labs for scientistswishing advanced training in plant biochemistry andmolecular biology. The core laboratories of thiscenter are united in their interest in the fundamentalprocesses of plant lipid and carbohydrate biosynthe-sis. The long term goal of the center is to provide thebasic knowledge which will permit genetic manipu-lation of crop species to produce new classes ofindustrially valuable lipids and carbohydrates.For information about this program contact one ofthe following individuals at Michigan State University,East Lansing, MI 48824:* John B. Ohirogge

Dept. of Botany and Plant PathologyBiochemistry and molecular biology of plant lipidsynthesis

* Jack PreissDept. of BiochemistryBiochemistry and molecular biology ot plant andmicrobial carbohydrate synthesis

* Christopher R. SomervillePlant Research Laboratory and Dept. of Botany andPlant PathologyBiochemistry, genetics and molecular biology of plantlipid synthesis

* N. Edward TolbertDept. of BiochemistryPhotosynthetic carbon metabolism, peroxisomes,glycerol metabolism. , n ,,I.n - -..

Ph.D.-Molecular BiologistMerck Sharp & Dohme Research Laboratories is currently offering anexcellent career opportunity for a Ph.D. level Molecular Biologist inthe Department of Cellular and Molecular Biology. Research in thisdepartment focuses on the isolation and expression of genes ofpotential pharmaceutical interest, in addition to the development oflive viral vectors. Past successes within this department have beenthe development of Recombivax', the first licensed human vaccinederived by recombinant DNA technologies, and the use of liveVaricella viruses as vectors. Another significant strength of thisdepartment is the application of recombinant yeast expressionsystems. Merck Sharp & Dohme Research Laboratories provides anenvironment that enhances scientific growth and productivity andencourages scientific publications and attendance at scientificmeetings.We are seeking a highly motivated individual with a desire for a posi-tion of visibility and leadership. Relevant interest and experience infull length cDNA library construction, new viral vector applicationsand protein structure-function relationships are desirable. A Ph.D. inMolecular Biology/Biochemistry/Microbiology or the equivalent is re-quired with at least four years of significant postdoctoral andacademic/industrial experience.Excellent salary and benefits programs accompany this position atour modern research facilities in West Point, Pennsylvania.Please send your resume, Including the names of three professionalreferences whom we may contact, and salary requirements In com-plete confidence to:

Manager, Pesonnel Relations, (W42-2)

Merck Sharp & DohmeResearch Laboratories

West Point, PA 19486EEO/AA/VH/Employer

c

9I

NATIONAL INSTITUTES OF HEALTHPUBLIC HEALTH SERVICE

NATIONAL CANCER INSTITUTEDIVISION OF CANCER TREATMENT

OFFICER OF THE DIRECTORDeputy Director, Medical Officer,

GM-602-15Salary: $58,135 - $72,500, depending upon qualifications. Anadditional bonus of up to $20,000 per year is available throughthe Physicians Comparability Allowance.

Applicants should be Board certified in a medical or surgicalspecialty, or in radiotherapy, and should possess compre-hensive knowledge of the preclinical and clinical sciencesrelating to cancer. Additional experience as an independentclinical investigator welcomed. Applicants should have masteryof both oral and written communications.

Primary responsibilities of the Deputy Director involve assist-ing the Director in conceptualization, design and implemen-tation of short- and long-range plans related to Divisionalresearch programs of both an intramural and extramural(contract or grant-supported) nature. Deputy Director repre-sents the Director and the DCT at various scientific meetings,international forums, and national media sessions; assists in theday-to-day management of the Division including establish-ment of operating plans and policies, budget development, andintegration of Division program with other Divisions, Institutes,and organizations; suggests scientific areas to pursue based onreview of proposed programs and the knowledge of currentdevelopments in the field of cancer treatment.

Point of Contact for Further Information: Mr. Lawrence J. Ray,Administrative Officer, Division of Cancer Treatment, NationalCancer Institute, NIH; 9000 Rockville Pike, Bldg. 31/Room3A50; Bethesda, Maryland 20892, Phone: (301) 496-2775.

Deadline for applications is Nov. 28,1988NIH is an Equal Opportunity Employer

L

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_

TRUSTEE PROFESSORSHIP INCOMPUTER SCIENCE SYSTEMSApplications/recommendations are invited for this newlyestablished Trustee Professorship in the Department of Com-puter and Information Science at the University of Pennsylvania.Strong interactions with the following departments and schoolswithin the University provide an interdisciplinary matrix In whichthe Computer and Information Science Program thrives: Elec-trical Engineering, Chemical Engineering, and MechanicalEngineering (in the School of Engineering and Applied Science);Linguistics, Philosophy, Psychology, and Mathematics (in theSchool of Arts and Sciences under the auspices of the CognitiveScience Program and the Lo9ic and Computation Group); theWharton School and the Medical School.

The person appointed to the Trustee Professorship will be adistinguished scholar who has performed outstanding researchof both theoretical and practical significance, especially in oneor more of the areas of computer systems,-computer architec-ture, parallel processing, programming languages and softwareengineering, among others. The incumbent should not only beable to exercise scholarly leadership in his/her areas of exper-tise, but should also be willing to interact with one or more of thedepartment's major interdisciplinary research activities.

Applications and nominations should be directed to ProfessorAravind K. Joshi, Chair, Trustee Professorship Search Committee

Uni'versity of

rll PennsylvaniaDepartment of Computer andInformation Science

WX/ Philadelphia, PA 19104-6389Equal Oppty./Affirmative Action Employer

BOEHRINGER INGELHEIM PHARMACEUTICALS, Inc., a majorresearcher, developer, manufacturer and marketer of prescription and over-the-counter drugs, currently has an opening in the Viral Drug DiscoveryGroup at our Research and Development Center located in DANBURY,CONNECTICUT.

The successful candidate we seek should have an MS Degree orequivalent in Molecular Biology/Cell Biology with 3+ years laboratoryexperience. Requirements include an understanding of cell biology,immunochemical techniques, DNA purification/ligation and restrictionenzyme analysis, purification of proteins in prokaryotic expression systems,gene cloning and gel electrophoresis lab systems.

Our state-of-the-art environment is combined with a highly competitivecompensation/benefits package and the opportunity to have yourcontributions recognized.

Please send your resume and salary history to: Dept. PTG-1J, R&D,BOEHRINGER INGELHEIM PHARMACEUTICALS, Inc., 90 East Ridge,PO. Box 368, Ridgefield, CT 06877. We are an equal opportunity employerm/f/h/v.

| i Boehringer\j~fIM Ingeiheim

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICSLAB AND WE

ABOUT YOUR PROPOSEDWILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

ERI

CANCER BIOLOGIST / RESEARCHSCIENTIST (Ph.D.)

The growth of our research consulting firm has createdan excellent opportunity for a CANCER BIOLOGIST. to joina group of scientists in the design of experimental studies.in the preparation of literature reviews and in the conductof health-risk assessments. The ideal candidate will possessa Ph.D. with 0-3 years postdoctoral experience in the celland tissue biology of cancer (e.g. tumor promoters. growthfactors. mutagenesis). Excellent analytical and communica-tion skills are a must.

ERI is a rapidly-growing environmental research andinformation consulting firm. with offices in New York City.Watertown (Mass.) and Palo Alto (Calif.). We offer qualifiedcandidates a challenging and rewarding work environment.top salaries commensurate with experience. and a fullbenefits package. This opening is at the New York Cityoffice. Please send Resume to:

Dr. William H. BaileyErvironmental Research Infornation, Inc.

575 Bghth AvenueNew York, N.Y. 10018-3011

ERI. Inc. is an Equal Opportunity Employer

Lm

DIRECTOR,NEUROTOXICOLOGY

DIVISION

The U.S. Environmental Protection Agency (EPA) isseeking candidates for the position of Director, Neuro-toxicology Division (NTD). This position is located in theHealth Effects Research Laboratory (HERL), ResearchTriangle Park, NC. This is a permanent full-time positionwith a salary range of $54,907 to $71,377 per annum

commensurate with qualifications.

HERL has a staff of about 325, over 100 of whom holddoctoral level degrees. The Laboratory has a diverseprogram which includes in vitro, animal, human clinical,and epidemiological research designed to address issuesrelated to the health effects of air and water chemicaland biological pollutants.

THE NTD is a multidisciplinary program organized intothree branches: Behavioral Toxicology, Neurophysiologyand Systems Engineering with a combined staff of 33.The Division is a focal point for planning, conducting, co-

ordinating, supporting and evaluating a program aimed atstudying the effects of chemical and/or physical agentson nervous system functions. The program includes bothintramural investigations and extramural arrangementswith universities, industry, private research institutionsand other government agencies. The primary responsibil-ities of the Director are to direct and manage the pro-gram. This includes developing the program to meet theevolving needs of EPA, presenting the program, develop-ing and managing budgets, supervising the staff, direct-ing the progress of the program, and ensuring the scien-tific quality and productivity of the program.

Qualifications for the position include:

1. Advanced degree in Pharmacology, Toxicology, Psy-chology, Physiology or Biology with a minimum of sixyears of professional research experience in any ofthese areas. Applicable graduate coursework may besubstituted for a portion of the required experience.This required education and experience must includea substantial background in neurotoxicology.

2. Experience in developing and managing budgets.3. Experience as supervisor of a scientific/professional

staff.4. Applicants must have recognized scientific expertise

as evidenced by multiple publications in peer-reviewedliterature and invitations to participate in nationaland international meetings/panels.

5. Proven abilitiy to provide leadership in directing thedevelopment and progress of a creative and effectiveresearch program in neurotoxicology.

6. U.S. Citizenship is required.Forward curriculum vitae and names of three referencesprior to December 2, 1988 to:

Dr. Lawrence W. Reiterc/o Terri Burrell, HRMD (MD-291U.S. Environmental Protection AgencyResearch Triangle Park, NC 27711

AN EQUAL OPPORTUNITY EMPLOYER

AAAS EXECUTIVE OFFICERThe American Association for the Advance-

ment of Science (AAAS) is conducting asearch to fill the position of Executive Officer.This position reports to the Chairman of theelected Board of Directors.The Association, founded in 1848, is a

501C(3) not-for-profit organization. It has anindividual international membership of135,000 and is affiliated with nearly 300 scien-tific, engineering, and learned societies. Theprincipal publication of AAAS is Science. TheExecutive Officer serves as publisher of thisweekly international journal. A staff of some230 people, headquartered in Washington,DC, handles the Association's publishing ac-tivities, as well as the planning and support ofannual meetings and symposia, a range ofspecial programs in science, education, inter-national cooperation, science and public poli-cy, opportunities in science, and science com-munication.The Board of Directors is seeking a person

of substantial experience and accomplish-ment. Appropriate background may be in sci-entific or engineering research, education, ac-ademic administration, scientific or technicalsociety management and/or publishing, orpublic administration of research and develop-ment policy. Initiative, management skill, andknowledge of the interactions of science withpublic policy are salient requirements. Suc-cessful candidate must have 15 years of rele-vant experience in one or more of the aboveareas including 10 years of experience inplanning, budgeting, and management. De-monstrable interest in the goals of the AAAS isessential. Salary is negotiable.

Letters of application, accompanied by cur-riculum vitae, should be addressed to:

Executive Officer Search CommitteeChairman, Walter E. Massey,

President, AAASc/o William R. Engelman

1333 H Street N.W., Washington, DC 20005Telephone: (202)326-6470

The closing date for receipt of applica-tions is 9 December 1988.AAAS, one of the largest general science

organizations in the world, is an Equal Oppor-tunity Employer.

POSITIONS OPEN

FACULTY POSMONS INMOLECULAR EVOLUTION AND

POPULATION BIOLOGYThe Department of Biological Sciences, University of

Cincinnati is expanding its research and teaching in theareas ofpopulanon biology and evolution and announcesthe availability of three tenure-track positions at theassistant professor level for the 1989-1990 academicyear. The University of Cincinnati has an enrollment ofapproximately 36,000 students and the department cur-rently has 29 full-time faculty in the biological sciencesand a graduate enrollment of 65 students, approximately60% of whom are pursuing the Ph.D. degree. Theopenings include: (i) MOLECULAR EVOLUTION-ARY BIOLOGIST: Conduct research using moleculartechniques to address questions in evolutionary biology.(ii) EVOLUTIONARY ECOLOGIST: Conduct re-search directed toward understanding species interac-tions (e.g. cocvolution; host/parasite; plant/pollinator).Preference will be given to those using mathematical and/or molecular/biochemical approaches in their research.(iii) POPULATION BIOLOGIST: Conduct researchusing quantitative approaches and field experimentationin the study of plant or animal populations. Preferencewill be given to those who can interact with our plantsciences faculty. Successful candidates will be expected todevelop vigorous, externally funded research programs,train graduate students, and teach courses at the under-graduate and graduate levels. The Ph.D. is required andpostdoctoral experience is preferred. Applicants shouldsubmit a description of their research interests and futureresearch plans, a current curriculum vitae, and threeletters of reference to: Dr. J. Robie Vestal, EvolutionSearch Committees, Department of Biological Sci-ences, University of Cincinnati, Cincinnati, OH45221-0006 by 1 December 1988. Candidates shouldindicate the position for which they are applying. TheUniversity of Cincinnati is an Equal Opportunity/AfirmativeAction Employer.

The Retrovirus Diseases Branch, Centers for DiseasesControl, Atlanta, Georgia, invites application for a posi-tion as MEDICAL EPIDEMIOLOGIST. Responsi-bilities include working on various aspects of the epide-miology of non-AIDS retroviruses including desianingand conducting studies concerning the seroprev ence,transmission, and risk factors for HTLV-I/II infection,risk factors for the development ofATL or TSP, as wellas designing and implementing surveillance systems forATL. Knowledge/expertise in molecular epidemiologywill be necessary as the applicant will also be expected todevelop and conduct molecular research related to theepidemiology of these retroviruses. Applicant must holda medical doctorate degree, have epidemiologic trainngand 3 years of experience in outbreak investigation andthe design and analysis of prospective epidemiologicstudies, year of experience in the design and executionofepidemiologic studies related to retroviruses, residencyand Board certification in internal medicine, specialtytraining in infectious diseases, and 2 years of bench-typeexperience in molecular biology. Salary range is fromapproximately $39,471 to $59,781 depending on experi-ence. Submit curriculum vitae and names of three refer-ences to: Sharlyn Wilkdnson, Personnel ManagementOffice, Building 1, Room 1058, Centers for DiscaseControl, Atlanta, GA 30333; for technical questions,contact: Dr. Thomas Folks, Chief, Retrovirus Dis-eases Branch, Centers for Discase Control, Atlanta,GA 30333. Telephone number: 404-639-3628. CDCis an Equal Opportunity Employer and providesfor a smokefreework environment. Applications must be received within 3weeks of publication date.

NMR SPECTROSCOPIST/POSTDOCTORALRESEARCH AFFILIATE: Stanford Magnetic Reso-nance Laboratory has a position open for a postdoctoralresearcher with expenence in NMR spectroscopy.SMRL systems include a Bruker AM-500, HX-360 andBruker Biospec II Horizontal Imaging Spectrometer.Current research projects focus on the development of invivo NMR techniques, the structure of proteins insolution and mechanisms of action of the trp repressor.Proficiency with 2DFI NMR techniques essential. Can-didates must have a Ph.D. in chemistry, physics, or arelated field. Contact: Dr. Oleg Jardetzky, StanfordMagnctic Resonance Laboratory, Stanford Universi-ty, Stanford, CA 94305-5055. Stanford is an AffirmativeAction/Equal Employment Opportunity Employer.

FACULTY POSITIONS IN VISION RE-SEARCH: The Combined Program in Ophthalmology,Eye Foundation Hospital-University ofAtabama (UAB)at Birminghamn School of Medicine will accept applica-tions for tenure-track, faculty positions (two) at theassistant professor level. Applications are invited fromindividual with a demonstrated ability to conduct pro-ductive independent research in the areas of visual psy-chophysics and retinal pharmacology/anatomy. Success-ful applicants will be expected to obtain and maintainextramural grant support. Laboratory space, appropriatestart-up support, and the facilities of UAB's interdepart-mental Vision Science Research Center are available.Interested and qualified individuals should submit curric-ulum vitae, statement of research interests and threeletters of reference to: Dr. Harold W. Skalka, Chair-man, Department of Ophthalmology, School ofMedicine/Eye Foundation Hospital University ofAl-abama at Birmingham, UAB Station, Birmingham,AL 35294. UAB is an Affirmative Action/Equal Opportuni-ty Employer.

HUMAN NUTRMIION ANDFOOD SCIENCE

The Departement de Nutrition of the Universite deMontreal invites application for two FACULTY POSI-TIONS in the areas of Human Nutrition and FoodScience. Candidates should hold a Ph.D. or M.D. andPh.D., with preferably postdoctoral training or experi-ence in research. They will teach in the undergraduateand graduate programs, and are expected to developindependent research programs. Knowledge of Frenchmust be sufficient to enable candidates to teach in Frenchwithin 2 years of the appointment. Send curriculumvitae, outhne of research program, and three letters ofreference to: Dr. Eugenio Rasio, Director, Departe-ment de nutrition, tYniversit6 de Montral, P.O. Box6128, Station A, Montreal, Qc, Canada, H3C 3J7.

In accordance with Canadian laws, preference will be given toCanadians and landed immigrants.

INFECTIOUS DISEASES-The Division of Infec-tious Diseases, Department of Medicine, Stanford Uni-versity School of Medicine invites aphlications for atenure-line position at the rank ofASSISTANT PRO-FESSOR.An outstanding opportunity exists to pursuean academic clinical research career for an individual withexcellent clinical and teaching skills and ability to conductindependent research. The successful candidate will bestationed at the VA-affiliated hospital that is geographi-cally near the Stanford Medical Center. Applicantsshould send curriculum vitae, a brief statement of re-search interests, and three names for reference to: PeterO'Hanley, M.D., Ph.D., Chief, Infectious Diseases(111), Veterans Administration Hospital, 3801 Mir-anda Avenue, Palo Alto, CA 94304. Stanford Universityis committed to increasing representation ofwomen and membersof minority groups on its faculty and particularly encouragesapplicationsfrom such candidates.

MOLECULAR NEUROBIOLOGY RESEARCH.Postdoctoral research position available in molecularneurobiology to study voltage gated ion channels. Amultidiscipline approach includmg electrophysiology,protein purification and recombinant DNA techniqueswill be used. A highy motivated individual who iswilling to work with other scientists and has a back-ground in molecular biology or biochemistry is pre-erred. Please send resume and names of three references

to: Dr. A. Blume, Molecular Neurobiology, c/o Mau-reen Quigley, Professional Employment Repre-sentative, Lederle Laboratories, American CynamidCompany, Pearl River, NY 10965. Equal OpportunityEmployer.

OCEANOGRAPHY: STAFF SCIENTIST posi-tion is available to teach oceanography in an innovativeundergraduate program, Sea Semester. Courses consistof6 weeks of intensive classroom instruction followed by6 weeks of teaching on board our sailing research vesselsin waters between the Caribbean and Newfoundland.Successful candidates will teach two courses per year,spending about 15 weeks per year at sea. Ph.D. in marinescience required. Starting date May 1989. Please sendresumn and three letters of recommendation by 15November 1988 to: Dr. Jerry Cheney, Sea EducationAssociation, P.O. Box 6, Woods Hole, MA 02543.An Equal Opportunity Employer.

LABORATORY RESEARCH SPECIALISTImmediate opening in the section of Endocrinology

and Metabolism in the ECU School of Medicine for ascientist to conduct and supervise basic research indiabetes. The candidate must have a Master's Degree in arelated field and several years of research laboratoryexperience. Expertise in protein chemistry, cell isolationand tissue culture are required. Salary range: $22,704 to$36,336. Please submit detailed resumn to: PersonnelDepartment, East Carolina University, Greenville,NC 27858. Telephonc: 919-757-6352.

Federal law requires proper documentation of identity andemployability at the time of employment. It is requested thisdocumentation be induded with your application. East CarolinaUniversity is an Afirmative Action/Equal Employment Oppor-tunity Employer, and encourages applications from qualifiedwomen and minorities.

NEUROBIOLOGIST, research faculty position, as-sistant or associate level, to develop an independentresearch program in neurochemistry or molecular biolo-gy. Federally funded through 1991, the position canb come a tenure-track, State-funded position. Applicantsshould have postdoctoral experience appropriate to therank, provide evidence of independent research produc-tivity and of potential to obtain extramural funding.Earliest starting date 2 January 1989. Send a resurnestatement of research interests, representative publica-tions, and names of three references to: Dr. I. Cooke,University of Hawaii, PBRC, 1993 East-West Road,Honolulu, HI 96822, by 9 December 1988. Inquinres:808-948-6776. Interviews available at Society for Neu-roscience meeting. Equal Employment/Affirmative ActionEmployer.

OCEAN/WEATHER MONITORING AND RE-SEARCH: MARINE RESOURCES SCIENTIST I.Full-time entry level position in a fisheries laboratorylocated in a beautiful resort town on the Maine coast.Requires baccalaureate degree and minimum of 2 yearsof experience or equivalent in ocean science or relatedfield. Knowledge of computer-based data management/statistics, fisheries oceanography, electronics and remotesensing desirable. Applicants should contact: EmilyMorris, Bureau of Human Resources, State HouseStation #4, Augusta, ME 04333. Telephone: 207-289-3761 to request application packet. Deadline: 8December 1988. Affirmative Action/Equal OpportunityEmployer.

PHARMACOLOGYFACULTY POSITIONOHIO UNIVERSITY

The Program in Physiology and Pharmacology atOhio University seeks to fill a tenure-track pharmacologyfaculty position at the assistant or associate professorlevel. A Ph.D. degree in pharmacology and 2 years ofpostdoctoral research experience is required. This posi-tion is a joint appointment in the College of OsteopathicMedicine and the Department of Zoological and Bio-medical Sciences. Although preference may be given tocandidates with training ancdexpertise in neuropharma-cology, candidates from other specialties are stronglyencouraged to apply. The successf candidate is expect-ed to develop a strong, independent and externallyfundable research program. Collaborative opportunitiesexist in several areas including: biochemical pharmacolo-gy particularly signal transduction and second messen-gers in stimulus response coupling, cardiovascular andautonomic pharmacology, endocrinology, molecular andcellular biofogy, smooth muscle physiology and neurobi-ology. The successful candidate is required to participatein teaching of pharmacology to osteopathic medicalstudents, and to participate in training ofgraduate (M.S./Ph.D.) students in the Program in Physiology andPharmacology within the Department of Zoological andBiomedical Sciences.The letter of application, curriculum vitae, description

of current and future research plans, copies of mostsignificant publications, and three letters of recommen-dation must be received by 15 December 1988. Addressto: The Chairperson, Pharmacology Search Commit-tee, Program in Physiology and Pharmacology,Room 228, Irvine Hall, Ohio University, Athens,OH 45701.

Ohio University is an Affirmative Action/Equal OpportunityEmployer.

SCIENCE, VOL. 242620

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

NEUROBIOLOGY. Franklin and Marshall Collegeseeks a broadly trained neuroscientist for a new tenure-track position as ASSISTANT PROFESSOR, begin.ning 1 July 1989, to teach neuroscience and areas such asintroductory biology or cell biology. A commitment toresearch, including work with undergraduates, is alsoessential. Candidates should bring a diversity of ap-proaches to modem neurobiology. A research laboratoryand start-up research support are available. This coeduca-tional liberal arts college has a strong progrm in thesciences. Send curriculum vitae, graduate and undergrad-uate transcripts, and statement of research interests by 5December 1988, and arrange to have three letters ofrecommendation sent to: Dr. David King, DepartmentofBiology, Franklin and Marshall College, Lancaster,PA 17604-3003. Women and members of minority groupsare encouraged to apply. An Equal Opportunity Employer.

NEUROSCIENTISTA basic research position in neurochemistry, neuroim-

munology, neuropharmacology, or molecular neurobiol-ogy, is available at the R. S. Dow Neurological SciencesInstitute of Good Samaritan Hospital and Medical Cen-ter. Persons with interests in neural regeneration, plastic-ity, development, transmitter or receptor function areespecially encouraged to apply. Opportunities exist forinteraction with basic research programs related to CNSfunction and with active clinical programs in neurosur-gery and neurology. M.D. or Ph.D. and postdoctoralexperience required. Substantial startup funds from the"Cooper Foundation for Neurologic Research and Edu-cation" are available, with the expectation that continuedfunding will be from extramuraf grant support. Level ofappointrnent will depend upon experience. Please submitresume and names of three references by 15 December1988 to: Robert S. Dow, M.D./Ph.D., Chairman,Irving Spencer Cooper Laboratory Search Commit-tee, Good Samaritan Hospital and Medical Center,1015 NW 22nd Avenue, Portland, OR 97210. GoodSamaritan Hospital and Medical Center is an Equal Opportuni-ty Employer.

OPTICAL PHYSICISTFaculty position for optical physicist to do research

and teach in new Biomedical Imaging Division. Individ-ual desired whose area of interest would complementthose of existing members of an active and growingbiomedical imaging group composed of biomedical re-searchers, mathematicians, computer scientists, and engi-neers. Possible areas of interest of applicant: confocalnicroscopy, high speed imaging, holography. Modemimage processing facilities available to the candidate.Joint appointment at nearby engineering school alsopossible. Rank and salary are negotiable depending onbackground and experience of applicant. To apply sendby 30 November 1988 curriculum vitae and names ofthree references to:

Dr. Fredric S. FayUniversity of Massachusetts

Medical Center55 Lake Avenue NorthWorcester, MA 01655

University of Massachusetts Medical Center is an EqualOpportunity/Affirmative Action Employer.

PHYSIOLOGISTApplications are invited for an anticipated tenure-track

assistant professor position in the Department of Zoolo-gy and Physiology, Louisiana State Universitv. TheDepartment is seeking an individual with research com-petence in one of the following areas to complement itsexisting strengths in comparative physiology: neuroen-docrine/neurosensory physiology, comparative biochem-ist and membrane biophysics. The successful candidatewill be expected to establish a strong research programand contribute to graduate and undergraduate teaching,primarily in vertebrate systems physiology. Candidatesmust have the Ph.D. degree and postdoctoral training ispreferred. Salary commensurate with qualifications andexperience. Applicants should send curriculum vitae, astatement of research and teaching interests, and namesof three references by 15 January 1989 to: Dr. Albert H.Meier, Department of Zoology and Physiology, Loui-siana State University, Baton Rouge, LA 70803-1725 (Telephone: 504-388-1132 BITNET:ZOOPHYS @ LSUVM). LSU is an Equal Opportunity!Affirmative Action Employer.

28 OCTOBER I988

At the forefront of biomedicalresearch, Program Resources, Inc.(PRI) is paving the way for newprograms and discoveries at theNational Cancer Institute's Freder-ick Research Facility.We are seeking a uniquely skilledprofessional to direct our PeptideSynthesis Laboratory which sup-ports the Synthetic Peptide AntigenSection of the National Institute of

Allergy and Infectious Diseases.Expertise in peptide synthesis usingsolid phase techniques by auto-mated t-BOC or FMOC chemistries;purification and protein sequencing/analysis is essential. Lab manage-ment experience desirable.You'll work in a campus-like settingin Frederick, MD near Baltimoreand Washington, D.C. Plus, PRI willreward your expertise with a salarycommensurate with credentials andan attractive fringe benefits program,including insurances, relocationallowance, and a 401 (K) savingsplan. For consideration, please for-ward CV in confidence to BarbaraNorton-Gill, Technical Recruiter.

PROGRAM RESOURCES, INC.NCI-FCRFP.O. Box BFrederick, MD 21701

RI PROGRAMRESOURCES,INC.

An equal opportunity employer.

WORKSAFEAUSTRALIA

(NATIONAL OCCUPATIONAL HEALTH AND SAFETY COMMISSION)NATIONAL INSTITUTE OFOCCUPATIONAL HEALTHANDSAFETY

The National Institute is seeking a suitably qualified person for appointment to thefollowing position which is located in Sydney, Australia. The successful applicantmay be offered an appropriate academic title at the University of Sydney.

HEAD - ERGONOMICS UNIT$A50,1 03-$A66,831

The successful applicant will be responsible for the development and supervision of a unitwhich will undertake research, high level consultancy and teaching in the ergonomics field.Tasks will include the administration and overall development of the Unit; the development,oversight and co-ordination of research activities of the ergonomics laboratory, and ofpostgraduate teaching and curriculum development.Applicants should possess a successful record of productive research and postgraduatenqualifications in an appropriate discipline. Experience in graduate and postgraduote teaching,

IIncluding supervision of PhD and Masters research is high y desirable.Further information on this position is available from Dr E. A. Emmett; telephone Sydney(02) 265 7501.Duty statement and selection criteria may be obtained from Mrs M. Carrasco; telephoneSydney (02) 265 7454.To be eligible for appointment, applicants must hold Australian citizenship. However,applicants who are accepted for immigration and are willing to take out Australian citizenshipmay be appointed on probation pending their obtaining citizenship. In some circumstances, afixed-term engagement of up to five years may be negotiated.Applications, together with curriculum vitae giving details of qualifications, experience andpublications, and the names of three referees slou[d be sent by 3rd February, 1989, to:

Executive Officer, Personnel OperationsWorksafe Australia

GPO Box 58, Sydney, NSW 2001 AUSTRALIAAN EQUAL OPPORTUNITY EMPLOYER

SCIENTIST

POSITIONS OPEN

PLANT BIOCHEMISTThe Department of Botany, University of Florida

invites applications for a tenure-track assistant professor-ship. The appointee will be expected to establish avigorous research program that complements existingstrengths in ecology, physiology and systematics. Teach-ing will include participation in undergraduate and grad-uate courses. Submit curriculum vitae and a statement ofresearch interests, and have letters from four referees sentto: Dr. J. Thomas Mullins, Search Committee Chair,Department ofBotany, University ofFlorida, Gaines-ville, FL 32611 by 16 December 1988.

The University of Florida is an Affirmative Action/EqualOpportunity Employer.

PLANT POPULATIONBIOLOGIST/ECOLOGIST

The Department of Biology at Trinity Universityinvites applcations for a tenure-track assistant professorposition beginning August 1989. Candidates must pos-sess a Ph.D., and have interests in mechanisms-orientedplant population biology. Duties include the develop-ment of a lecture/laboratory course in the area of special-ity, participation in core courses for majors, and academ-ic advising. The successful candidate will also be expectedto establish a vigorous research program in which under-graduates can participate.

Applicants should send curriculum vitae, summary ofresearch experience and names of three references to:Professor Thomas L., Koppenheffer, Chairman, De-partment of Biology, Trnity University, San Anto-nio, TX 78284. Application deadline is 17 November1988. Women and minority candidates are strongly encouragedto apply.

Trinity University is an Equal Opportunity/AffirmativeAction Employer.

PLANT SYSTEMATICSThe Rancho Santa Ana Botanic Garden invites appli-

cations for a staff position in systematic and evolutionarybotany, available 1 September 1989. Individuals special-izing in cytogenetics are particularly encouraged to ap-ply. The successful candidate will be expected to maintaina vigorous, independent research program and to partici-pate in the graduate program in Botany. Applicantsrepresenting various levels of experience are welcome,corresponding with assistant professor to full professorlevels, and if hired, will be appointed to the faculty oftheClaremont Graduate School. Send curriculum vitae,statement of research interests, reprints, and at least threeletters of reference by 15 December 1988 to: SearchComnittee, Rancho Santa Ana Botanic Garden,1500 North College Avenue, Claremont, CA 91711.

POSTDOCTORAL AND/OR RESEARCHASSOCIATE POSITIONS IN

CELL BIOLOGYPositions are available for persons interested in pro-

jects involving functional and molecular aspects of thecytoskeletal system of cells from different human tissues.Emphasis is being placed on studies of human diseaseswhich are related to alterations in cytoskeletal or cellsurface components. Applicants should possess a Ph.D.degree with experience in cell biology, biochemistry,and/or molecular biology.

Please send a recent curriculum vitae to: Dr. RobertD. Goldman, Department ofCell Biology and Anato-my, Northwestern University MedicalSchool, 303East Chicago Avenue, Chicago, IL 60611.

Northwestern University is an Equal Opportunity/Afirma-tive Aaion Employer and invites applications from all qualifiedindividuals.

LADY DAVIS INSTITUTEPOSTDOCTORAL FELLOWSHIPS

Postdoctoral positions available immediately for ongo-ing research programs investigating various molecularaspects of gene expression and the control of cell prolif-eration. Expertise m biochemistry, cell and/or molecularbiology essental.Send inquiries, curriculum vitae, and names and ad-

dresses of three references to: Dr. Herbert M. Schul-man, Acting Director, Lady Davis Institute for Medi-cal Research, Sir Mortimer B. Davis Jewish GcneralHospital, 3755 Cote Ste-Catherine, Montreal, Que-bec, Canada, H3T 1E2.

622

POSITIONS OPEN

WAKSMAN INSTITUTE/MERCK POSTDOC-TORAL FELLOW. A fellowship provided by Merck,Inc. is available mid 1989 at the Waksman Institute forstudy of microbial systems. Applicants can choose fromseveral diverse areas of research: Protein-DNA interac-tion and transcription-Dr. R. Ebright. Structural stud-ies of important microbial enzyme systems-Dr. A.Goldman. Diversity in nitrogen-fixing actinomycetes-Dr. H. and M. Lechevalier. Protein degradation in E.coli-Dr. L. Simon. DNA replicationtmutagenesis-Dr.N. Sinha. Interested individuals should contact prospec-tive mentors directly for discussion of possible projectsand completion of application. For consideration, sendcurriculum vitae to one of the Institute members aboveat: Waksman Institute, Rutgers University, P.O. Box759, Piscataway, NJ 08855-0759. An Equal Opportuni-ty/Affirmative Action Employer.

POSTDOCTORAL FELLOW Position is availableto study free radical processes in cells and the pathwaysby which these reacuve species mediate cell injury. Weseek individuals with training in cell biology, biochemis-try and chemistry to join an active research program.Send curriculum vitae and references to: Dr. Gerald M.Rosen, Department of Pharmacology and Toxicolo-gy, University of Maryland School of Pharmacy, 20North Pine Street, Baltimore, MD 21201.

POSTDOCTORAL FELLOW IN ECOLOGYApplications are solicited for an anticipated 2-year

postdoctoral appointment beginning August 1989 withpreferred interests in animal-microbe interactions inaquatic systems or larval ecology. The successful appli-cant will initiate an independent research program, par-ticipate in on-going departmental research projects, andteach one course per academic year. Salary commensuratewith qualifications and expenence. Closing date is 15January 1989. Please send curriculum vitae, a letterdescribing research interests and three letters of recom-mendation to: Dr. John Fleeger, Department of Zool-ogy and Physiology, Louisiana State University(LSU), Baton Rouge, LA 70803-1725 (Telephone:504-388-1738 BITNET: ZOFLEE @ LSUMVS).LSU is an Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL FELLOWSHIPin molecular biology of genes expressed in connectivetissues with special emphasis on mutations that producegenetic diseases. Opportunities will be provided to learncurrent recombinant DNA technologies and to developnew ones. Applicants must have Ph.D. in biochemistryor related areas. Salary competitive. Apply to and sendletters of recommendation to: D. J. Prockop, JeffersonInstitute ofMolecular Medicine, Department of Bio-chemistry, Thomas Jefferson University, 1020 LocustSt., Philadelphia, PA 19107.

Equal Opportunity Employer

POSTDOCTORAL POSITION available 1 January1989 to characterize T cell receptors on human alloreac-tive T cell clones. Experience in tissue culture techniquesand molecular biology including cDNA cloning andsequencing are essential. Fellows have an opportunity tointeract with an active immunogenetics group withdiverse interests. Interested individuals should submit acurrent curriculum vitae including bibliography, briefstatement of relevant experience, and the names of threereferences to: Dr. Carlyn Hurley, Microbiology De-partment, Georgetown University School of Medi-cne, 3900 Reservoir Road NW, Washington, DC20007.

POSTDOCTORAL POSITION available in thefield ofbone marrow stem cell research and bone marrowtransplantation. Current projects include the influence ofthe pedigree of donor marrow on long term hematopoi-etic function in recipients following marrow transplanta-tion, mechanisms of engraftment and graft rejection ofT depleted marrow across varying genetic barriers, andthe role and long term effect of lymphokine use inengraftmnent and hematopoietic recovery following mar-row transplantation. Salary is negotiable depending onexperience. Applicants should send curriculum vitae andthree letters of reference to: Dr. Peter Mauch, JointCenter for Radiation Therapy, Harvard MedicalSchool, 50 Binney Street, Boston, MA 02115. AnEqual Opportunity Employer.

POSITIONS OPEN

POSTDOCTORAL POSITION available 1 Decem-ber 1988 to study the use of fetal cortical transplants inthe repair of CNS lesions in the newborn rat. Back-ground in immunocytochemistry, electrophysiology, liq-uid chromatography, or receptor binding is desirable.Send curriculum vitae and the names of three referencesto: Dr. Anthony J. Castro, Department of Anatomy,Loyola University Stritch School of Medicine, May-wood, IL 60153. Loyola University of Chicago MedicalCenter is an Equal Opportunity Educator and Employer.

POSTDOCTORAL POSITION. Available imme-diately for cell and molecular biologist to participate in acomprehensive study examining DNA repair mecha-nisms and cellular recovery processes and their relation-ship to radiation resistance m cultured insect cells. Em-phasis will be on isolation of genetic material associatedwith the pronounced radioresistance. Experience in mod-em molecular biology techniques desirable. Please sub-mit curriculum vitae and names of three references to:Dr. T. M. Koval, Department of Oncology, MayoClinic, Rochester, MN 55905. An Equal Opportunity!Affir,native Action Institution.

POSTDOCTORAL POSITIONAvailable immediately, for computer studies of protein

structure and folding. Applicant should have strongbackground in biophysical chemistry and computer Pro-gramming. Starting salary $20,000. Send curricuumvitae, statement of research interests, and names of threereferences to:

Dr. George RoseDepartment of Biological Chemistry

The Milton S. Hershey Medical CenterThe Pennsylvania State University

P.O. Box 850PHershey, PA 17033

An Equal Opportunity/Afirmative Action Employer

POSTDOCTORAL POSITION available immedi-ately to join a well-established research program usingthree-dimensional electron microscope tomography toinvestigate the three-dimensional structure ofmitotic andpolytene chromosomes. Of fundamental interest is un-derstanding the higher order structure of chromosomesthroughout the mitotic cell cycle and to relate suchstructural dynamics to chromosome function. Thick-section tomographic data is collected using our 300-KvPhillips EM430 IVEM with an ultra-high tilt (±800)eucentric stage and a cooled 10242 CCD image detector.State-of-the-art computation and image display systemsare available. Applicants should send curriculum vitaeand names and ademsses of three referees to either: Drs.David A. Agard or John W. Sedat, HHMI StructuralBiology Unit, Department of Biochemistry, UCSFMedical Center, San Francisco, CA 94143-0448.

POSTDOCTORAL POSITION available immedi-ately to study any ofthe following areas of blood plateletbiochemnistry: receptor/G-protein/protein kinase regula-tion of cellular responses; regulation of the phosphoino-sitide and arachidonic acid-mobilizing systems; intra-cellular fluorescence measurements of Ca 2 and pH; andthe mokcular biology of the protein components of theIP3- activated Ca2+ mobilizing system. A strong back-ground in protein biochemistry, biophysics, or molecularbiology is required. Send curriculum vitae and threeletters of reference to:

Dr. Maurice B. FeinsteinDepartment of Pharmacology

University of Connecticut Health CenterFarmington, CT 06032

An Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSITIONA postdoctoral position is available to genetically

construct microbial strains capable of degrading toxicchemicals, and to study the molecular basis of suchdegradation. The work is to be performed at the Biotech-nology Research Laboratory of the U.S. Army at Aber-deen Proving Ground in Maryland; approximate annualsalary $32,000. The project is for 3 years under thesupervision of A. M. Chakrabarty. Please send curricu-lum vitae and the names of three references to: A. M.Chakrabarty, University of Illinois College of Medi-cine, Department ofMicrobiology/Immunology, 835South Wolcott, Chicago, IL 60612.

SCIENCE, VOL. 242

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- \K APRIL

CHOLYBARPOAIDILANTIN

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POSITIONS OPEN

POSTDOCTORAL POSITIONUNIVERSITY OF PENNSYLVANIA

MEDICAL SCHOOLA position is available immediately to study the regula-

tion of gene expression in growvth factor stimrulatedimmune cells. Primar wvork involves either GM-CSFstimulated mvelopoiesis or IL-2 stimulated lyvmphocyteproliferation.Send curriculum vitae and the names and addresses of

three references to:Dr. Michael B. PrystowskyDepartment of PathologyUniversity of Pennsylvania

Philadelphia, PA 19104-6082

POSTDOCTORAL POSITION available January1989 for NIH-funded studies on the role of oxidativestress and energy in cardiac reperfusion injury. Thecandidate should have a recent Ph.D. in pharmacology,biochemistnr or a related field. Experience in membraneisolation is desirable. Send curriculum vitae and twoletters of recommendation to: James P. Kehrer, Ph.D.,Division of Pharmacology, College of Pharmacy, TheUniversity of Texas at Austin, Austin, TX 78712. AnEqu4al Opporttuity Emnployer.

POSTDOCTORAL POSITIONUNIVERSITY OF PENNSYLVANIA

MEDICAL SCHOOLA position is available immediately to studv mecha-

nisms of human oncogene activation and function inlvmphomas and lvmphoid leukemias. Primary Nwork in-volves novel oncogenes cloned from translocation break-

ints, and encompasses investigations of oncogenefunction through gene transfer, regulation of oncogeneexpression, an characterization of oncogenic proteins.

Send curriculum vitae and the names and addresses ofthree references to:

Dr. John C. ReedDepartment of Pathology

School of MedicineUniversity of Pennsylvania

Philadelphia, PA 19104-6082

POSITIONS OPEN

POSTDOCTORAL POSITION in immunologv, tostudv mechanisms of induction and maintenance oftolerance in T lymphocvtes. Focus on biochemical eventsresponsible for tolerance in cloned T cell lines. RecentPh.D. in immunology, biochemistry or molecular biolo-gy preferred. Send resume and names of three referencesto: Dr. Helen Quill, Department of Pathology, Uni-versity of Pennsylvania School ofMedicine, Philadel-phia, PA 19104-6082. Aut Equal Opportuntity Emnployer.

POSTDOCTORAL POSITION available immedi-atelv for molecular biologist to join research programstudying mechanisms of antigen recognition, regulation,ontogenr, and effector properties of epitheial and muco-sal T cells. Salary in accord with NIH guidelines; excel-lent benefits. Send curriculum vitae and names of threereferences to: Dr. John R. Klein, Department ofBiologi-cal Science, The University of Tulsa, Tulsa, OK 74104.An Equal Opportuntity/Affirmative Actiout Emnployer.

POSTDOCTORAL POSITION INCELLULAR NEUROBIOLOGY

Position available immediately to study physiologyand pharmacology of synaptic events in the spinal slicepreparation and molecular mechanisms of tachvkininactior\s. Project involves the use of single-electrode volt-age-clamping and wvhole-cell voltage-clamping with apatch blectrode. Send curriculum vitae, statement ofresearch interests, and names of three references to:Mirjana Randic, Department of Veterinary Physiolo-gy and Pharmacology, College of Veterinary Medi-cine, Iowa State University, Ames, IA 50010. Closingdate: 15 January 1989.

POSTDOCTORAL POSITION IN NEUROBI-OLOGY to studv cell surface and extracellular matrixmolecules that regulate cell-cell interactions in the des-el-oping mammalian nervous system [see Dev. Biol. 120,65 (1987); BioEssays 9, 19 (1988)]. Send curriculumvitae and names of three references to: Dr. GeraldSchwarting, Department of Biochemistry, E. K. Shri-ver Center, 200 Trapelo Road, Waltham, MA 02254.An Equal Opportutnity Emnployer.

POSITIONS OPEN

POSTDOCTORAL POSITION available to studymolecular structure-function relationships of the interac-tion of neurotropic viruses and neurotoxins with theacetvlcholine receptor and other neuronal receptors andto develop antiviral agents. Background desired inrecombinant DNA techniques, protein chemistr, virolo-gy, or tissue culture. Beginning position available imme-diately. Send curriculum vitac and addresses of threereferences to: Dr. Thomas L. Lentz, Department ofCell Biology, Yale University School of Medicine,333 Cedar Street, P.O. Box 3333, New Haven, CT06510. Yale University is an Equal Opportutnity Employer.

POSTDOCTORAL POSITIONS available for nvoscientists interested in molecular biology, cell biology,and immunology of hepatoma or esophageal carcinoma.Salary: U.S. $14,000 with possibility of free housing.Send curriculum vitae and three references to: ProfessorChungming Chang, Graduate Institute ofMicrobiol-ogy and Immunology, National Yang-Ming MedicalCollege, Shih-Pai,Taipei, Taiwan, Republic of China.

POSTDOCTORAL POSITIONS: We anticipateopenings at various times during the coming year forseveral postdoctoral positions with members ofthe Grad-uate Group in Immunology at the University of Pennsyl-vania and other associated institutions. Research pro-grams involve basic studies in T-cell, B-cell, and macro-phage immunology, immunogenetics, viral immunology,and include disease-associated immune phenomena. Ap-plicants must be U.S. citizens or permanent residents andshould be recent degree recipients. For further informa-tion, please contact: Ms. Gail Heimberger, Adminis-trative Assistant, Immunology Graduate Group,2023 Nurses Education Building, University ofPennsylvania, Philadelphia, PA 19104-6020. To ap-plv, send current curriculum vitae and the names of threereferences, one of 'which must be your present researchmentor, to: Dr. John J. Cebra, Department of Biolo-gy, University of Pennsylvania, Philadelphia, PA19104-6018.

The Untiversity of Petntnsylvaniia is ani Equial Opportutiit)yEmployer

DeanColumbian College of Arts & SciencesThe George Washington University

Applications and nominations are invited for the position of Dean ofColumbian College. the undergraduate liberal arts component of TheGeorge Washington University. The Dean is the principal administrativeofficer and educational leader of the college, which has an enrollment ofabout 3,300 in programs in arts, humanities, social sciences, sciences andmathematics. The George Washington University is a private, non-sectarian university with undergraduate, graduate and professionalprograms, located in one campus in the heart of Washington, D.C. Thelocation provides unparalleled opportunities for programs which drawupon the resources of the nation's capital.Candidates should possess an earned doctorate or other appropriateterminal degree, significant administrative experience, and suitable quali-fications for senior appointment in one of the departments or programsof the College. The Search Committee will seek evidence of a compre-hensive vision for qualitative growth in liberal arts colleges and awarenessof the specialized needs and opportunities afforded by our location.* Salary: commensurate with experience and qualifications* Preferred starting date: July 1, 1989* Closing date for applications: Dec. 20, 1988

Send nomination or letter of application, resume, anda short statement of personal educational goals andphilosophy to:Chair, Columbian College Search Committee,c/o Vice President for Academic AffairsRice Hall

GhEo()RGE The George Washington UniversityW.XSHING0ToN Washington, D.C. 20052U NlX RSIT GW is an affirmative action. equal opportunity employer.

NASI

DIRECTORPOSTDOCIDRAL PROGRAMS &GRADUATE EDUCATION POUCYThe OFFICE of SCIENTIFIC AND ENGI-NEERING PERSONNEL of the NATIONALRESEARCH COUNCIL is seeking candidatesfor Director of Associateship Programs.Candidates should have a Ph.D. or equiva-lent, preferably in physical or biologicalsciences, engineering or mathematicswith a combination of at least 10 years ofproductive faculty teaching, research, andadministrative experience at the graduatelevel, including supervision of seniorscientists and staff and adminsrtion of pro-gram financing and budgets. The selectedcandidate will have responsibility for thedirection of the Associateship Programs, thesalient activity of the Office of Scientificand Engineering Personnel (OSEP), main-taining 25 contracts, totaling $32m at 75national laboratories, overseeing 500postdoctoral appointments. The selectedcandidate will also serve as a consultantto the executive director of OSEP ongraduate education policies, identifying andresponding to issues of national concern.This position requires experience workingwith a broad spectrum of the graduatecommunity from university presidents tograduate and postgraduate students. Sendresume in confidence to:

A. Fetcher, Executive DirectorOFFICE OF SCIENTIFIC ANDENGINEERING PERSONNEL2101 Constitution Avenue, N.W.

Washington, D.C. 20418EOE

I InternationalIOpportunitiesfor Ph.D11..J. Life ScientistProcter & Gamble has several entry-level Functions for these disciplines includeopenings for life scientists with Ph.D. or product development, toxicology, environ-postdoctoral training in the following mental sciences, regulatory affairs, anddisciplines: microbiology.

Biochemistry Virology Openings are in Brussels, Belgium;Microbiology Biostatistics Newcastle or Egham, England; SchwalbachPharmay .Immunology (near Frankfurt) or Mainz, Germany; Osaka,

Pharmacy . Japan; Caracas, Venezuela, or Mexico City,

FBiology Ecology Mexico. Applicants must be bilingualBi aology Eology (including English). Not all discipline

openings are available at all locations.

EMPLOYMENT IS CONTINGENT UPON POSSESSION OFAPPROPRIATE CITIZENSHIP, IMMIGRATION VISA, OR

POSITIONS IN: WORK PERMIT FROM COUNTRIES INDICATED BELOW:

Belgium, England . . Britain, Ireland, Denmark, Norway, Finland,and Germany Sweden, Holland, Belgium, France, Luxembourg,

Portugal, Greece, Austria, Switzerland, Italy,Spain, or Germany

Japan.. JapanMexico and ....... Mexico, Venezuela, Puerto Rico, Colombia, Chile,Venezuela Brazil, or Peru

Procter & Gamble is a multinational, lent benefits package including pension,technically-based corporation with over health care, and paid relocation.$19 billion in world-wide sales in the To apply, please send your resume andpharmaceutical, health care, beauty care, publication list to the address below.paper, household care, beverage, food, Specify appropriate country(ies).detergent, and fabric care consumer prod- D T J Loauct categories. We have consumer brands r. . . oganin 38 product categories with sales in 140 International Life Science Openingscountries. Support of research and product The Procter & Gamble Companydevelopment reached $652 million last year. Miami Valley LaboratoriesWe offer a stimulating environment for P.O. Box 398707

personal and professional growth in a Cincinnati, Ohio 45239-8707strong and growing company. Salaries are Allow 8-10 weeks for response.highly competitive, coupled with an excel- No agency referrals, please.

m

POSITIONS OPEN

POSTDOCTORAL POSITION IN PHYSIOLO-GY OF AGING available immediately for quantitativestudv of dendritic structure and synaptic physiology inhippocampus in a mammaliani model of aging. Studytechniques include intracellular recording, intracellulardye marking, analysis of svnaptic potentials, and mathe-matical reconstruction of neurons. Experience in cellularneurophvsiologv desirable but wvill consider alternativebackgrounds. Applicants should send curriculum vitaeto: D. A. Turner, Neurosurgery, 112N, VeteransAdministration Medical Center, One Veteran Drive,Minneapolis, MN 55417.

POSTDOCTORAL POSITIONS available imme-diatelv. One position requires molecular biologv experi-ence to characterize genes encoding dechlorinating en-zvmes from a Flavobacteriion spp. Second position re-quires a background in biochemistry with experience inenzyme immobilization techniques. Individuals will par-ticipate in a project to degrade synthetic organics in situusing extracellular enzvmes. Salary is $21,000 per yearfor 2 vears. Send curriculum vitae and names of threereferences to: Dr. Cindy S. Orser, Department ofBiochemistry and Bacteriology, University of Idaho,Moscow, ID 83843. Att Equial Opportutnity/AffinnativeActioni Emnployer.

POSTDOCTORAL/RESEARCH ASSOCIATEto study the photoperiodic control of body and lipidmass and reproduction in hamsters as orchestrated by thepineal gland and melatonin. Studies include identifica-tion of CNS and peripheral target sites for melatonin'seffects and fat-pad-specific changes in lipid metabolism.Experience with the following techniques desirable: im-munocytochemistry and/or tract tracing, RIA, or in vitrofat cell metabolism. Send curriculum vitae and names ofthree references to: Dr. Timothy J. Bartness, Depart-ments of Psychology and Biology, Georgia StateUniversity, Atlanta, GA 30303 by 1 January 1989.Georgia State Utniversity, a unit of the University systemof Georgia, is an Equal Opportunity/Affirmative ActionEmnployer.

A POSTDOCTORAL RESEARCH ASSOCIATEposition is available immediately.We are seeking candi-dates wvith a doctorate in molecular/cellular biology,genetics or related disciplines and/or experience in plantmolecular/cellular biology to w%ork on a collaborativeproject with Drs. N. J. Panapoulos and S. E. Lindow atthe Department of Plant Pathologv, University of Cali-fornia, Berkeley, CA (UCB). The wvork wvill involve thetransfer of a bacterial gene into plants and the quantifica-tion of its expression in different cells and organelles. Thecandidate will work mostly at UCB but may spend shortperiods of time at Oregon State University. Applicationdeadline 15 November 1988. Interested candidatesshould send their resume, transcripts, and provide namesof three references to: Dr. Tony Chen, Department ofHorticulture, Oregon State University, Corvallis, OR97331-2911. Telephone: 503-754-3695. OSU is anAffirnative Actiotn/Equal Opportitoiity Emnployer atnd comnpliesivith Sectiotn 504 of the Rehabilitationt Act of 1973. OSU lias apolicy of beinig respontsive to the nteeds of dual-career couples.

POSTDOCTORAL RESEARCH POSITION,immediately available, devoted to the purification andmolecular biology of human platelet thromboxane A,receptors. Opportunitv to work with an interdisciplinarvgroup. Experience wvith protein purification desired.Send curriculum vitae to: Dr. Perry V. Halushka,Department of Cell and Molecular Pharmacology,Medical University of South Carolina, 171 AshleyAvenue, Charleston, SC 29425. MUSC is ani EqualOpportuintity/Afinnative Actiont Emiployer.

RESEARCH ASSISTANT to perform synthesis andanalysis of heterocyclic compounds utilizing chromatog-raphy, spectrophotometrr and spectroscopy. The struc-ture-activitv relationship of the synthesized compoundswill be determined with pteridine dependent enzymesinvolved in cancer chemotherapv and neurotransmittersvnthesis. Require M.S. in organic/biochemistnr and 2vears of experience in heterocvcic svnthesis. Salary:$17,500 per year for 40-hour week. Apply with resumeto: Deborah Abernathy, Alabama State EmploymentService, P.O. Box 81309, Mobile, AL 36689, or applyin person at any Alabama State Employment ServiceOffice. Job Order Number AL0595630. Equal Einploy-metit Opportunity.

626

POSITIONS OPEN

POSTDOCTORAL RESEARCH ASSOCIATEposition available beginning 1 February 1989 for quanti-tative single-unit neurophvsiological and correlative ana-tomical studies of ascending pathways relevant to noci-ception, thermoreception and endogenous opioid anal-getic mechanisms in a unique and vital multidisciplinarresearch institute. Direct application (curriculum vitae,references and a brief description of interests) and inquir-ies to: Dr. A. D. Craig, Division of Neurobiology,Barrow Neurological Institute, 350 West ThomasRoad, Phoenix, AZ 85013. Equal Opportunity Etnployer.

POSTDOCTORAL RESEARCH POSITION-Postdoctoral training position in the molecular cell biolo-gv of clathrin coated membranes. Focus is on the regula-tion of coat assembly in cells and on coat-membranereceptor interactions in endocytosis. Experience in pro-tein chemistrv or molecular biology preferred but notrequired. Send curriculum vitae and names of threereferences to: Dr. James H. Keen, Fels Institute forCancer Research and Molecular Biology, TempleUniversity School of Medicine, Philadelphia, PA19140. Ant Equal Opportunity/Affirmative Action Employer.

Applications are invited for a PROFESSORSHIPIN MARINE GEOLOGY at the Institute of GeologyUniversity of Aarhus, Denmark. The position is availablefrom 1 March 1989.The Institute of Geology has been engaged in research

within the field of marine geology, using geophvsical,sedimentological and biostratigraphical methods. Re-search has mainlv been related to Danish waters, but alsoto projects involving the ocean floor.The projects have involved basic research and applica-

tions related to raw materials and constructions.The Institute of Geologv wants to strengthen the

marine geological research milieu in the vears to come.Applicants with broadly based research fields who cancoordinate geophysical, sedimentological and biostrati-graphical efforts, as well as carrning out specializedresearch within one of these fields, wil be preferred.The position includes participation in teaching at all

levels.Each applicant should submit curriculum vitae, a

description of teaching experience, a list of publications,and three copies of publications to be considered in theevaluation. A statement of professional goals and re-search interests should be included.

According to Danish ministerial regulations, the selec-tion committee's written evaluation of the applicant issent to all applicants.

Applications should be addressed to the Queen ofDenmark, and sent to: University of Aarhus, Ndr.Ringgade 1, DK-8000 Aarhus C, Denmark, andmarked: 211-37. The deadline for the receipt of allapplication material is 2 January 1989, at 12:00.

For further information on salarv, research and teach-ing duties, staff, laboratorv and other facilities, pleasecontact: Gunnar Larsen, The Institute of Geology,C. F. M0olers Alle, Building 120, DK-8000, AarhusC. Telefon: 06 128233.

RESEARCH ASSISTANT PROFESSOR-TheUniversitv of Pennsvlvania Smell and Taste ResearchCenter and the Department of Otorhinolaryngology andHuman Communication seek a research assistant profes-sor. Applicants should have at least 4 vears of postdoctor-al experience and have publications in the areas ofradiation-induced taste aversion, animal taste psvcho-physics, and quantification of roden oromotor tasteresponses. Send curriculum vitae and letters of recom-mendation to: James B. Snow, Jr., M.D., 3400 SpruceStreet, Philadelphia, PA 19104. The Untiversity of Pennt-sylvaniia is an Equal Opportunity Emnployer.

RESEARCH ASSOCIATE/POSTDOCTORALPOSITION is available for a neuropharmacologist toparticipate in studies of brainstem and spinal regulationof nociceptive behavior. Appliants should have a Ph.D.or M.D. degree with research experience. The workinvolves neurochemical studies of nociceptive neuro-transmittters, stereotaxic catheter placement for microin-jetions, and the use of nociceptive testing paradigms.Send resume to: David J. Smith, Ph.D. (Anesthesiolo-gy/Pharmacolopy) at the Department of Anesthesiol-ogy, West Virginia University, Health Sciences Cen-ter, Morgantown, WV 26505. The positiont is finded bythe Utniversity Health Associates which is ant Equal Opportuniii-ty Etnployer/M/F/H.

POSITIONS OPEN

RESEARCH ASSISTANT PROFESSOR-TheUniversitv of Pennsylvania Smell and Taste ResearchCenter and the Department of Otorhinolaryngology andHuman Communication seek a research assistant profes-sor. Applicants should have at least 8 years of postdoctor-al experience and have publications in the areas of laserbioregulation and tissue culture. Send curriculum vitaeand letters of recommendation to: James B. Snow, Jr.,M.D., 3400 Spruce Street, Philadelphia, PA 19104.The Utniversity of Penntsylvaniia is ant Eqtual OpportunityEmployer.

RESEARCH ASSOCIATE: This position involvescvtogenetics research with rodent oocvtes, spermato-cytes, and early! embryos. Academic requirements includea degree in genetics/cell biology and 3 ylears of experiencein mammalian germ cell cytogenetics research. Salary is$21,000 per annum. Send curriculum vitae and refer-ences to: Camille Thomas, Human Resource Manage-ment, Louisiana State University School of Medicinein Shreveport, P.O. Box 33932, Shreveport, LA71130. Atn Equal Opportuniiity Emnployer.

RESEARCH SCIENTISTPHARMACOKINETICS

We are seeking a qualified research scientist to designand participate in several drug disposition studies ofnove chemical entities for eve and skin use; to conductpharmacokinetic studies to support drug discovery and/or toxicology; to supervise personnel for bioanalvticalanalyses; and to publish results in scientific literature.Must have Ph.D. in pharmaceutics, pharmaceuticalchemistry or pharmacology, and 1 Near of experience indrug disposition research of ocular drugs. Must demon-strate knowledge to apply pharmacokinetic principles toproblem solving in drug disposition, and must be famil-iar with bioanalvtical method development. Must possessexcellent written and oral communication skills and haveabilitv to work in multidisciplinanr environment. Salarvis $3;500 per month. Job site: Irvine, California. Sendthis ad and a resume to: Job# TC9931, P.O. Box9560, Sacramento, CA 95823-0560 not later than 12November 1988.

RESEARCH SCIENTISTSCalifornia State Department of Health Services, Divi-

sion of Laboratories has positions available for the civilservice classes of Research Scientist II and III (Environ-mental Biochemistry), and Research Scientist II (Atmo-spheric Chemistrv). Selection of the candidates wvill be onthe basis of a competitive examination, followed by jobinterviews. Candidates in environmental biochemistryshould demonstrate qualifications for appointments inwater chemistrv wAith emphasis on total organic analysisof natural waters (Level III), in environmental analyrsiswith emphasis on methods development, sampling andanalvsis for non-conventional po lutants, and environ-mental fate studies (Levels II and III). Candidates inatmospheric chemistry should demonstrate qualificationsfor appointments in electron microscopy and microprobeanalysis of air particulates and in incinerator performanceevaluation and incinerator field studies.

Level III is supervisory and requires leadership quali-ties besides an earned doctorate and minimum of 3 yearsof broad research experience in the last 7 vears in thestated specialty or a c[oselv related field. Level II is a leadposition requiring either a doctorate and a minimum of 2vears of relevant research experience in the last 5 years, ora M.S. degree and a minimum of 3 vears of research.

Final postmark date for submission of applications is 5December 1988. Request copy of examination an-nouncement with salarv information and an applicationform from: Division of Laboratories, California De-partment ofHealth Services, Room 452, 2151 Berke-ley Way, Berkeley, CA 94704. Telephone: 415-540-2408. Resume with list of publications must accompanyapplication.

An Equal Opporttutnity/Affirnative Actiotn Emnployer.

Louisiana State University (LSU) Eye Center is look-ing for a SENIOR PHARMACOLOGIST. Applicantshould be interested in drug delivery systems althoughother areas of research will be considered.

Previous experience in ophthalmology not necessary.Interested applicants send curriculum vitae to: Herbert E.Kaufman, M.D., LSU Eye Center, 2020 Gravier Street,Suite B, New Orleans, LA 70112. LSUMC is an EqualEmployment Opportunity/Afirmative Action Emnployer.

SCIENCE, VOL. 242

OPPORTUNITIESIN>2 BIOTECHNOWOGY

RepliGen Corporation is a leader in theapplication of Biotechnology to the health careand personal care markets. We are currentlydeveloping an AIDS vaccine and AIDStherapeutic products, products for the treatmentof infectious diseases, cancer therapies, andnovel biocompatible personal care products.We take pride in the high caliber of our scien-tific staff and our collaborations with majorresearch institutions and corporate partnersin Europe and the United States. The expan-sion of our effort has created the followingopportunities:

Cell Culture ServicesManager, Cell Culture Services-A Ph.D. ispreferred with 5 + years' experience in tissueculture and laboratory management. We arelooking for a Manager of Cell Culture Servicesto be responsible for coordinating mam-malian cell culture, insect cell culture, andcell-based assays. Experience in large-scaleproduction would be a plus.

Virology and CellBiologyResearch Scientist-This position requires aPh.D. in Virology or other appropriate fieldwith specialization in Virology. The scientistwould be expected to direct a group studyingHIV neutralization and cell surface interactions.Experience in human infectious agents isa must.

Research Associates/Technicians-BS/MS ina biological science and experience invirology and cell culture. Experience workingwith human pathogens would be helpful.RepliGen Corporation offers a competitivesalary, excellent benefits, and equity participa-tion. Please submit a cover letter, resume,and references to Barbara Fleming, Profes-sional Recruiter, RepliGen Corporation,One Kendall Square, Bldg. 700, Cambridge,MA 02139. An Equal Opportunity Employer.

Enzyme Purification& Molecular Cloning

CIBA-GEIGY Pharmaceuticals Division's 100acre headquarters complex in Summit, NewJersey is engaged in research and develop-ment of drugs to treat cardiovascular andother disorders.We seek a PhD in Biochemistry, MolecularBiology or a related field to participate in im-portant work involving purification andmolecular cloning of an enzyme of the car-diovascular system. To quali or this challeng-ing postdoctoral opportunity, you should alsohave training in one or more of the followingareas: protein purification, enzymology,molecular cloning.Salary and benefits are excellent, in a highlyprofessional environment. Apply in confidencewith resume and salary history to: CIBA-GEIGY Corporation, Staffing Center,Pharmaceuticals Division, Dept. ATR,556 Morris Avenue, Summit, New Jersey07901. We Are An Equal OpportunityEmployer M/F/H/V.

Science Serving Mankind

CIBA-GEIGY

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AMKROBIOLOGICALX~ ASSOCIATES INC.

MICROBIOLOGICAL ASSOCIATES has the following career opportunitiesfor senior scientific personnel.

DIRECTOR, MOLECULAR VIROLOGYApplicants should have a strong background in virology (preferably retro-viruses) and molecular biology. Responsibilities include the management ofgovernment contracts and research relating to HIV and other viruses, andthe development and execution of commercial assays.

SENIOR SCIENTIST, GENETIC TOXICOLOGYJoin our world-recognized Division of Genetic Toxicology. We are seeking aStudy Director with extensive experience performing bacterial mutagenesisassays, particularly the Ames test. Responsibilities include oversight of alarge technical staff, interaction with commercial clients and management ofseveral government contracts. You will join our cytogenetics, mammalianmutagenesis and DNA damage/repair teams in coordinated efforts to provideboth R&D and commercial testing services.

Prospective candidates should have excellent communication skills, both oraland written. Previous industrial experience is highly desirable.

Our state-of-the-art facility is located in the northern suburbs of Washington,D.C. We offer an excellent compensation, relocation and benefits package.Please join us as we continue to build on our 40-year commitment to highquality science. For immediate consideration send your resume to:

MICROBIOLOGICAL ASSOCIATES INC.Life Sciences Center

9900 Blackwell Road, Rockville, MD 20850EOE/m/f/h/v

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POSITIONS OPEN

RESEARCH TECHNICIAN: To studv the estro-gen and progesterone receptors in surgical samples ofpatients suffering from canccr and normal individuals. Toinvestigate any correlation between the biochemical char-acteristics of these receptors with time point of menstrualcycle or age. B.S. in biology and M.S. in endocrinology.Must be able to use tissue homogenizers, centrifuges,ultracentrifuge, liquid scintillation counters, analyticalbalance, SDS-PAGE Power supplv, light microscope,crvotomc, darkroom. Must be fluent in following tech-niques: SDS-PAGE, DCC, CPG, Immunoblotting, anddetection of radioactive bands by autoradiographv. Thir-tv-seven hours per week; 9 a.m. to 4 p.m.; $22,285 pervear. Applicants send resumc to: Illinois Department ofEmployment Security, 401 South State Street-3South, Chicago, IL 60605. Attention: Ms. MarieNinneman. Reference #7362. An emplover paid ad.

SUMMER FACULTY POSITIONSIN SLSTP, A NASA PROJECT

Four project counselor positions are open in the 1989Space Life Sciences Training Program (SLSTP) to beheld at the Kennedy Space Center, Florida. Projectcounselors will be involved in the implementation of the6-wAeek long program activities for undergraduate collegestudents. An applicant must have a minimum of M.S.degree, preferably Ph.D. degree and some experience ofteaching and research in life sciences and related fields. Ifinterested, please send a letter of application, completecurriculum vitae, and three letters of recommendationbefore 31 December 1988:

Program Director, SLSTPFlorida A&M UniversityCollege of Pharmacy

and Pharmaceutical SciencesP.O. Box 367

Tallahassee, FL 32307Telephone: 904-599-3636

CALIFORNIA STATE UNIVERSITY,HAYWARD

The Department of Biological Sciences invites applica-tions for a full-time TENURE-TRACK POSITION atassistant professor level, subject to budgetary approval,beginning September 1989. Ph.D. required. Expected toteach undergraduate lecture and laboratory%, major andnon-major courses; to teach graduate courses and con-duct seminars; to develop a productive, independenthfunded research program and to direct graduate studentsin M.S. degree program.TERRESTRIAL ANIMAL ECOLOGIST. Teach-

ing and research interests in population, community andecosystem ecology xith strong quantitative skills andfieldilaboratorv applications. Active participation in envi-ronmental biology program is expected.CSUH seeks to create a stimiulatinsq atnosphere for its

ethntically diverse faculty and sttudetnt population. Womtieni atndmninorities are especially encouraqed to apply. Interested indi-viduals should send a copy of their curriculum vitae, abrief summary of their teaching and research goals, andarrange to have three letters of reference sent to: Chair,Department of Biological Sciences, California StateUniversity, Hayward, Hayward, CA 94542. To beassured of full consideration, applications should bereceived bv 31 December 1988.

The Unitersity is atn Equial Opportuntiity!Affinnatiwe Actioni/Hatndicapped Etnployer.

University of California, Santa Barbara. TENURE-TRACK POSITION IN GEOGRAPHY-OCEAN-OGRAPHY, available 1 July 1989. Salary and rank are

dependent upon qualifications; however, preference willbe given at e assistant professor level. The GeographyDepartment seeks applicants with background in phvsi-cal oceanography and/or air-sea interaction with an inter-est in remote sensing. Ph.D. normally required at time ofappointment, substantial qualifications in marine re-

search, and a strong commitment to teaching and re-search. Submit resume and names of three references to:Chair, Search Committee, Department of Geogra-phy, University of California, Santa Barbara, CA93106. This search wTll continue until filled; first consid-eration will be given to applications received before 15january 1989. Equial Opportnttity/Ajfirnative Actiotn Em-ployer. Proof of U.S. citizetnship or eligibility for U.S.etnploymetnt will be reqtired prior to emnploymnetnt (ImtnigrationRefonn anid Conitrol Act of 1986).

628

POSITIONS OPEN

SENIOR RESEARCH INVESTIGATOR. Estab-lish and maintain a capability for research in molecularbiology, recombinant DNA, and microbial genetics; touse these techniques to generate novel microbial strainsfor improved phenvlalanine production and potentialnew products. Specifically, to make use of wide-rangingskills in protein englineering and special expertise vithGram-positive and thermophilic bacteria; instigate novelresearch. Ph.D. in genetics or microbiology requiredtogether with 1 year and 6 months of experience in thejob offered or 1 vear and 6 months of experience as apostdoctoral research associate or scientist. The requiredexperience must have involved the conduct of researchand development in the production of phenvlalanineutilizing Gram-negative, Gram-positive, and thermophil-ic bacteria as well as protein engineering. Forty hours;Monday to Friday; 9 a.m. to 5 p.m., $53,550 per xear.Send resume and Social Security number to: IllinoisDepartment of Employment Security, 401 SouthState Street-3 South, Chicago, IL 60605, Attention:Mr. Robert S. Felton, Reference # V-IL 8618-F. Anemplover paid ad.

SENIOR RESEARCH INVESTIGATOR. Estab-lish and maintain a capability for research in molecularbiology, recombinant DNA and microbial genetics; touse these techniques to generate novel microbial strainsfor improved phenvlalanine production and potentialnew products. Specifically, to work principallv on evalua-tion of genetically-engineered microorganisms in fer-mentations; design and implement a research programaimed at optimizing fermentation conditions and devel-oping new fermentation products. Ph.D. in biochemistryor microbiologv required together wvith 1 year and 6months of experience in the job offered or 1 year and 6months of experience as a postdoctoral research associateor scientist. The required experience must have involvedthe conduct of research and development in the produc-tion of phenvlalanine by optimization and process re-search o fermentations for aromatic amino acid svnthesiswith recombinant/non-recombinant strains of E. coli.Forty hours; Monday to Friday; 9 a.m. to 5 p.m.;$47,700 per ylear. Send resume and Social Securitnumber to: Illinois Department of Employment Se-curity, 401 South State Street-3 South, Chicago, IL60605, Attention: Mr. Robert S. Felton, Reference #V-IL 8620-F, An employer paid ad.

THE UNIVERSITY OF TULSATVWO TENURE-TRACK POSITIONS

1) MOLECULAR BIOLOGY/IMMUNOLOGY2) DEVELOPMENTAL GENETICS

Two assistant/associate professor positions in TheFaculty of Biological Science and The Mervin BovairdCenter for Studies in Molecular Biology and Biotechnol-ogv are available for fall 1989. Preferred areas of re-search: 1) molecular biologv ofthe immune response and2) animal developmental genetics; however, those inrelated disciplines are also encouraged to apply. Require-ments: Ph.D., postdoctoral experience and a publicationrecord indicative of the potential to establish and main-tain an externally funded research program. Salary andrank will be commensurate with experience. Generousstart-up funds and newly renovated laboratory space willbe provided. All faculty are expected to teach bothundergraduate and graduate students, and to maintain arecord of excellence and productivity in scholarly re-

search.The department has a faculty of 16 and offers B.S.,

M.S., and Ph.D. degrees. Extramural funding in 1987 to1988 totaled 2.7 million dollars. Facilities include state-of-the-art laboratories and equipment.The University of Tulsa is a private, heavily endowed,

comprehensive university with a strong conmmitment toteaching and research. The city of Tulsa is an economicand cultural center of 750,000 population, surroundedby lakes and located in the foothills of the OzarkMountains. Interviews will conmmence 1 December1988. Applicants and nominees should submit curricu-lum vitae, statement of research interests and three lettersof reference to:

Dr. Kenton S. MillerSearch Committee Chair

Faculty of Biological ScienceThe University of Tulsa

600 South College AvenueTulsa, OK 74104

Affinnative Action/Equ4al Opportunity Employer.

POSITIONS OPEN

TUMOR CELL GROWTH FACTOR GROUPPostdoctoral positions available to study the roles of

hormones, growth factors and new attachment proteinsin tumor cellgrowth. Indiv'iduals sought for projects: (i)Molecular Biologist to clone and sequence cDNA ofnew attachment proteins and modified thyroid hormoncand estrogen receptors. (ii) Cell Biologist/Immunolo-gist to develop monoclonal antibodies to grow%th factorreceptors for radioimmunotherapy and mechanism stud-ies. (iii) Biochemists (two) to purifx new serum proteinsand receptors regulating estrogen and thyroid hormonedependent growth. Salary: $23,000. Send curriculumvitae and names of three references to: Dr. David A.Sirbasku, Professor, Department of Biochemistry andMolecular Biology, University of Texas MedicalSchool, P.O. Box 20708, Houston, TX 77225. AnEqual Opportutnity/Afirnative Action Emnployer. Womneni atndmninorities are etncourged to apply.

FOX CHASE CANCER CENTERVIROLOGY FACULTY POSITIONS

The basic science component of the Fox Chase CancerCenter is expanding its program in sirologv. Currentprograms include: William Mason (hepadna viruses),Ann Marie Skalka (retroviruses), and John Taylor(hepatitis, delta virus and retrovirus). The Search Com-rnittee invites applications from new and establishedinvestigators to set up independent research programs.All positions are tenured or in tenure-track. Please sendcurriculum vitae and a letter describing current scientificinterest to: Dr. John Taylor, Virology Search Com-mittee, Fox Chase Cancer Center, 7701 BurholmeAvenue, Philadelphia, PA 19111. The Center is an EqtalOpportunity Employer.

SCIENCE, VOL. 242

THE UNIVERSITYOF IOWA

VICE PRESIDENTj FOR RESEARCH

=1647

The Vice President for Research promotes andfacilitates research and scholarship and fosterstheir excellence; strengthens relationships withpublic and private agencies that support researchand other scholarly endeavors; advances the roleof the University in economic development;develops research agreements; and formulatesand implements policies regarding research, pat-ents, copyrights, and intellectual property rights.The Vice President reports directlv to the Presi-dent.The Vice President should have an established

record of research accomplishment and the ca-pacity to promote research and scholarship andfoster their excellence in all areas of a compre-hensivre research university. Although adminis-trative experience is a highl desirable qualifi-cation, it is not a prerequisite. Candidates musthave the ability to communicate universint poli-cies relating to research to all of the University'sconstituencies, both internal and external. It isimportant that the Vice President have extensiveexperience and familiarity with funding agencies.The Vice President is expected to have a

Ph.D., or equivalent degree or achievement, andpreferablv also experience at a major researchorganization. The Presidetnt atnd the Search Comnmnit-tee are particularly eager to identitfy qualified womenanid mninority catndidates.The position will be available 1 Julv 1989.

Nominations will be accepted until the positionis filled. Screening vill begin immediatelv. Pleasesend nominations or applications to:

Professor John F. Kennedy, ChairSearch Committee

Vice President for Research101 Jessup Hall

The University of IowaIowa City, IA 52242

The Utiversity of Iowa is atn Equial Opportunlityanid Affir,native Actiotn Emnployer.

We have an immediate need for a Research Biologist tobecome part of our innovative tumor biology group. Thisposition provides an opportunity to do fundamentalresearch on the biochemical and cell biological basis oftumor metastases with an ultimate goal to identify novelantimetastatic agents. The applicant should have a Ph.D.in biological sciences with 1-2 years of post doctoral ex-perience in tumor metastasis research. The ability of theapplicant to work independently as demonstrated bypublication records and to work well as part of a group isessential.Merrell Dow Research Institute is located in suburban Cin-cinnati. We offer excellent compensation, comprehensivebenefits and relocation assistance. If you are interested infundamental research and would like to work for a rapid-ly growing research institute, please send your curriculumvitae with names of three references to:

Personnel Services ManagerRefer to Job Code SPS

MERRELL DOWRESEARCH INSTITUTE

2110 East Galbraith RoadCincinnati, OH 45215

Equal Opportunity Employer MIF/HN

TH E U N IVE R S ITY O F A D E LAI D ESOUTH AUSTRALIA

invites applications from both women and menfor appointment as:

DIRECTOROF THE WAITE AGRICULTURAL RESEARCH INSTITUTE(Ref: 1112) to succeed Professor J.P. Quirk A.O., F.T.S., F.A.A. who retires in1989.The Waite Agricultural Research Institute is the premier agricultural researchinstitute in Australia. In addition to conducting research in agriculture and alliedsubjects, the Institute provides facilities for teaching in the degree of B.Ag.Sc.and has a strong postgraduate school which draws students from a wide rangeof countries.The Director will be the research director and executive officer of the Institute.The University seeks a person with a distinguished record of scientific achieve-ment, outstanding leadership qualities and administrative ability of a high order.The appointment as Director of the Institute is for an initial term of seven earsand otherwise in accordance with the University Statute on the Waite Institute.FURTHER INFORMATION about the duties of the position and the generalconditions of appointment may be obtained from the Registrar at the University.SALARY per annum: Professorial salary plus 25% (presently at AUS$76,938),

plus other benefits.APPLICATIONS, IN DUPLICATE, quoting reference number 1112 and giving fullpersonal particulars (including whether candidates hold Australian permanentresidency status), details of academic qualifications and names and addresses ofthree referees should reach The Registrar at the University of Adelaide, GPOBox 498, Adelaide, South Australia, 5001, Telex UNIVAD AA 89141/Fax no.(618) 224 0464 not later than 16 December 1988.The University reserves the right to make enquiries of any person regarding anycandidate's suitability for appointment, not to make an appointment or toappoint by invitation.THE UNIVERSITY OF ADELAIDE IS AN EOUAL OPPORTUNITY EMPLOYER

WOODS HOLE OCEANOGRAPHICINSTITUTION

POSTDOCTORAL FELLOWSHIPS

Ocean Science and EngineeringApplications are invited from new or recent doctoratesin science or engineering with interests in physical ocea-nography, meteorology, marine chemistry, marine geol-ogy and geophysics, biological oceanography, or oceano-graphic engineering. Recipients of awards are selectedon a competitive basis, with primary emphasis placedon research promise.

Marine Policy and Ocean ManagementResearch fellowships are offered to individuals in the so-cial sciences, law, the humanities, or natural sciences toapply their training to problems or issues that involvethe use of the oceans. Presently research follows the-matic areas such as Marine Science and Public Policy;Ocean Jurisdictions, Law of the Sea, and InternationalRelations; Development and Management of Ocean Re-sources; and Areawide Planning and Management. Em-phasis is placed on the economics of ocean space and onthe role of science in governmental and industrial deci-sion making. Topics of special current interest includemarine biological diversity, the quality of marine habi-tats and marine reserves, and the impacts of sea-levelchange. Other research interests are also appropriate.

Fellowships are awarded for oine year with a stipendof $28,500 plus group health insurance and a modestresearch budget. Recipients are encouraged to pursuetheir own research interests independently or in associ-ation with resident staff. Completed applications mustbe received by January 15, 1989 for 1989-90 awards.Awards will be announced in March. Write for appli-cation forms to: Dean of Graduate Studies, P.O. BoxS, Woods Hole Oceanographic Institution, Woods Hole,Massachusetts 02543

Equal Opportunity/Affirmative Action Institution

Damon Biotech, Inc., a leading biotechnology companyengaged in developing and marketing biological products,is offering the following positions:

SUPERVISOR OF LARGE SCALECELL CULTURESupervise large scale mammalian cell culture departmentin GMP Pilot Lab. Experience in biochemical engineering,cell biology, tissue culture and with GMPs for manufac-turing of biological products.

GROUP LEADER,MEDIA PREPARATIONResponsible for supervising large scale media and solu-tions group in a GMP Pilot Lab. Experience with GMPrequirements for solution preparation and ability to super-vise diverse activities and support manufacturing.

DIRECTOR OF QUALITYCONTROL AND QUALITYASSURANCEManage all aspects of QC/QA for a biological productiongroup including testing, GMP compliance, validation, prod-uct release, and FDA inspections. Position requires 5 to10 years experience with a pharmaceutical or biologicalmanufacturer in the QC/QA function.

Interested applicants should send a resume to DamonBiotech, Inc, Human Resources, 119 Fourth Avenue, Need-ham Heights MA 02194. We are an equal opportunityemployer m/f/h/v.

1 ___ rL[E)A'J\lMKJBiotech

Merrell Dow

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RESEARCH GRANTS

VIROLOGISTDIVISION OF BIOLOGY AND MEDICINE

BROWN UNIVERSITYApplications are invited for a full-time, tenure-track

position in animal virology at the rank of assistantprofessor in the Section ofMolecular, Cell and Develop-mental Biologv comnuencing in the fall of 1989. We seekan individualwith at least I years ofpostdoctoral train-ing, who will establish an active, independent researchprogram and will interact effectively with other membersof the Graduate Program in Molecular Biology, CellBiology and Biochemistry. While we are interested inindividuals working with retroviruses, final selection willbe for candidates of outstanding ability regardless of thesystem studied. The successful candidate will participatein teaching virologv to medical, graduate and undergrad-uate students. Send curriculum vitae, recent reprints,summarv of research interests, and have three letters ofrecommendation fonrarded no later than 15 December1988 to: Dr. Peter R. Shank, Division of Biology andMedicine, Brown University, Providence, RI 02912.FAX: 401-863-3700. Brown Untiversity is an Equal Op-portunity/Affirmative Action Employer.

Viagene, Inc. is an expanding biopharmaceutical com-panv developing novel drugs and diagnostics based ongene delivery. We are seeking a VIROLOGIST, IM-MUNOLOGIST for a senior project management posi-tion with expertise in growing and characterizing retro-viruses. Candidates should have a Ph.D., M.D. or equiv-alent plus several years of research and project manage-ment experience. This is a challenging position in adynamic environment with good opportunitv for growthand advancement. Please send r6sume/curriculum vitaewith three references to:

Douglas Jolly, Ph.D.Director of Research

Viagrene, Inc.11075 Roselle StreetSan Diego, CA 92121

FELLOWSHIPS

GRADUATE FELLOWSHIPS available from theAmerican Psychological Association's Minority Fellow-ship Program/Neuroscience. The Program aims to in-crease the number of racial and ethnic minorities whocomplete the doctorate in the neuroscience field. TheProgram accepts applications,each fall (deadline 15 Janu-ary) from students who plan to pursue the Ph.D. at anvfull-time doctoral programn listed in Neuroscience TrainingPrograms in North Amerca. This federally funded programprovides awards for up to 3 years contingent on satisfac-torv academic progress in the doctoral program. Formore information, write:

The American Psychological AssociationMinority Fellowship Program/Neurocience

1200 17th Street, N.W.Washington, DC 20036Telephone: 202-955-7761

POSTDOCTORAL FELLOWSHIPS IN ENVI-RONMENTAL TOXICOLOGY AND PATHOLO-GY are available at Northwestem University MedicalSchool (NIH training grant). The preceptors and theirresearch areas are: Toshio Narahashi (Mechanisms ofaction of insecticides on neuronal ion channels by patchclamp); Philip lannaccone (Effects of carcinogens onmammalian embryo); Michael Morin (Antineoplasticagents: Signal transduction and therapeutic application);Ryoichi Oyasu (Mechanisms of urinary bladder cancer);M. Sambasiva Rao (Pancreatic carcinoma); JanardanK. Reddy (Pancreatic carcinoma and liver peroxisomeproliferators); Dante G. Scarpelli (Mechanisms of pan-creatic carcinoma); Jerome Seidenfeld (Mechanisms ofpancreatic carcinoma); Jerome Seidenfeld (Polyamines:Biosynthesis inhibitors and role in growth regulation;Dennis Solt (Carcinogen modification of epithelialcells); Chau H. Wu (Action of environmental toxins onnerve membranes by patch clamp). The applicants must beU.S. citizens or permanent residents. Send a letter stating a

specific area of interest, curriculum vitae, and threereference letters to: Dr. Toshio Narahashi, ProgramDirector, Department of Pharmacology, Northwest-em University Medical School, 303 East ChicagoAvenue, Chicago, IL 60611. Telephone: 312-908-8284. An Affirmative Action/Equal Opportunity Employer.

FELLOWSHIPS are available for pre- and postdoc-toral study in the PHARMACOLOGY GRADUATEPROGRAM of the Grace Cancer Drug Center, RoswellPark Memorial Institute, a Graduate Division of theState University of New York at Buffalo. Stipends andtuition waivers are available for eligible candidates. Theprogram offers diversified training related to the pharma-cological, molecular and biochemical basis or drugaction with emphasis on cancer therapeutics. Specificareas include: cellular differentiation and wth regula-tion; cellular ultrastructure; oncogenes; g resistance;.immunopharmacology and metabolic regulators; inhibi-tion or alteration of nucleic acid; protein and membranecomponents; pharmacokinetics and drug metabolism;mechanisms of carcinogenesis; genetic basis for drugaction; precinical and dinical pharmacology; medicinalchemistry and toxicology. U.S. citizens and permanentresidents may send applications to:

E. Mihich, M.D., ChairmanGraduate PharmacoloFy ProgramRoswell Park Memorial Institute

Grace Cancer Drug CenterElm and Carlton Streets

Buffalo, NY 14263Please include curriculum vitae and indicate two refer-

ences. An Equal Opportunity/Afirmative Action Employer.

ASSISTANTSHIPS

The newly formed Institute for Biotechnology at TexasTech University announces the creation of RE-SEARCH ASSISTANTSHIPS for graduate studyleading to the Ph.D. degree in the areas of biochemistry,cell biology, genetics, microbiology, or molecular biolo-gy. Beginning in the spring of1989, a total of fiveassistantships in the amount of $12,000 per year arebeing offered by the Departments of Biological Sciences,Chemistry and Biochemistry, and Agronomy, Horticul-ture and Entomology. Interested applicants should applvfor admission into one of the three departments before 1December 1988. Those students seeking admnission forspring 1989 are encouraged to apply as soon as possible.For more information, contact: Dr. David B. Knaff,Director, Institute for Biotechnology, P.O. Box4260, Texas Tech University, Lubboclk TX 79409.

GRANTS

PARKINSON RESEARCH GRANTSOUTSIDE UNIVERSITY OF MIAMI

1 JUNE 1989-31 MAY 1990The National Parkinson Foundation, ofMiami, Flori-

da, invites the submission of grant proposals for Parkin-son research. A total of $200,000 will be made availableto support basic bench research on Parkinson's Disease.None ofthe monies are to be utilizedfor administrative overhead.The award for a single grant will not exceed $40,000.The application deadline is 1 February 1989; grantstarting date will be 1 June 1989. It is required thatproposed studies specifically focus on mechanisms in-volved in the disease process and that they have thepotential of finding the cause and prevention of Parkin-son's Disease. Proposals will be assessed by the NationalParkinson Foundation Scientific Advisory Board. Toobtain submission information, please write to:

National Parkinson Foundation, Inc.Research Grants

1501 N. W. 9th AvenueMiami, FL 333136

PROGRAM

CAREER CHANGE OPPORTUNITY

This unique program offers the candidate with an

eamed doctorate in the sciences the opportunity toobtain the Doctor of Optometry (O.D.) degree in twocalendar years. Employment opportunities exist in pri-vate practice, industry, education and research. Contact:Dr. D. Chauncey, Program Director, AcceleratedProgram, The New England College of OptometryRoom S, 424 Beacon Street, Boston, MA 02115.

RESEARCH INQUIRIES INVITEDThe Smokeless Tobacco Research Council, Inc. invites

inquiries regarding grant applications.The Council sponsors independent research into ques-

tions of smokeless tobacco and health. Research supportis through a program of grants-in-aid.Grant applications are evaluated by the Scientific

Advisory Board to the Council and will be judged solelyon the basis of scientific merit and relevance.

Deadlines for submission of grant applications are 31December for 1 July funding and 30 June for 1 Januaryfunding. Address inquines or requests for applicationsto: The Smokeless Tobacco Research Council, Inc.,420 Lexington Avenue, New York, NY 10170. Tele-phone: 212-697-3485.

TRAINING PROGRAM

PREDOCTORAL ANDPOSTDOCTORAL TRAINING INHUMAN CANCER BIOLOGY AT

THE UNIVERSITY OF WISCONSINApplications are invited for graduate studv toward the

Ph.D. degree and for postdoctoral Traineeships in Hu-man Cancer Biology. Financial assistance will be awardedon a competitive basis. Postdoctoral Traineeships are restrictedto U.S. citizens and those with permanent U.S. residence visas.

Research areas include experimental pharmacologyand cancer endocrinology, biological response modifiersand cancer immunology, biology and biochemistry ofcarcinogenesis and tumor promotion, and radiation biol-ogy. The Department ofHuman Oncology is the coredepartment ofthe UWCCC, an NCI-designated compre-hensive cancer center.

For information, write:Chairnan, Graduate Steering Committee

Department ofHuman OncologyK4/33OUW Clinical Cancer Center

600 Highland AvenueMadison, WI 53792

The University of Wisconsin-Madison is atn Equal Opportu-nity/Affirmative Action Employer.

Opportunities for scientific TRAINING in trauma-related subjects with a multidisciplinarv group, fundedby NIH training grant. Tenure 2 vears, possible exten-tion to three. U.S. citizenship, 3 years of surgical train-ing, and commitment to trauma research required. Lim-ited number of non-surgeon Ph.D.'s. Emphasis is onacquisition of scientific skills. Write: Trauma Training,University of California Medical Center, 839 HSE,San Francisco, CA 94143-0522. UC is an EqualOpportunity/Afirmative Action Employer and encourages ap-plicationsfrom women and minorities.

MARKETPLACE

S___d b ed _ JWA3. $1.5 abo.ned. $2.00ab per Ubwn&

Result from your purfied DNA In I weekStadard primr Included.

200bme minimum.Research Genetics

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ANTI-VIRAL DRUG TESTING FOR HIVPan-Data Systems, Inc. (PDS), offers assist-ance in drug testing using freshly isolated mono-cyte/macrophage cultures and PHA-stimulatedleukocytes.Contact Dr. John Dahlberg, Director of Re-search, for more information:

13 Taft Court, Rockville, Md. 20850(301) 294-2297 fax (8095)

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