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HIMSS Turkey Presentation 1
Personalized Health and the Integration of Genomics
Dr. Wolfram Otto and Mr. Hal Wolf
HIMSS Turkey Presentation
Primary Prevention
Secondary Prevention
Acute Care
Chronic Care
Personalization touches all aspects of care
2
Creating new data with each touch point
HIMSS Turkey Presentation
Moving From a Medical to Health Model
Popula'on Care Mass Produc'on
Sub Segmenta'on (risk and condi'on-‐based)
Other Medical Condi'ons
Pa'ent Preferences Personal Circumstances
Genomics Personalized Health
HIMSS Turkey Presentation
Moving From a Medical to Health Model
Popula'on Care Mass Produc'on
Sub Segmenta'on (risk and condi'on-‐based)
Integrated Medical Condi'ons
Personal circumstances
Pa'ent Preferences (aBtudes, behaviours)
Genomics
Personalized Health
MEDI
CAL
SOCI
AL
HIMSS Turkey Presentation
Moving From a Medical to Health Model
Popula'on Care Mass Produc'on
Sub Segmenta'on (risk and condi'on-‐based)
Integrated Medical Condi'ons
Personal circumstances
Pa'ent Preferences (aBtudes, behaviours)
Genomics
Personalized Health
MEDI
CAL
SOCI
AL
HIMSS Turkey Presentation
Moving From a Medical to Health Model
Popula'on Care Mass Produc'on
Sub Segmenta'on (risk and condi'on-‐based)
Integrated Medical Condi'ons
Personal circumstances
Pa'ent Preferences (aBtudes, behaviours)
Genomics
Personalized Health
MEDI
CAL
SOCI
AL
HIMSS Turkey Presentation
Programs must facilitate continuous patient engagement.
HIMSS Turkey Presentation
All parts of the Eco-system must align…
Pa'ent
GP
Social Care
Hospital
Gov.
HIMSS Turkey Presentation
The Clinical Ecosystem Impacted
Process Technology
• Clinical Operations • Administration • Payor System • Legal • Patients
• Mobile devices • Patient and Clinical
• Genomic Labs • IT Infrastructure / Systems • Facilities
People • Physicians • Nurses • Other Care Providers • Patients
HIMSS Turkey Presentation
Beyond Population Care Management • Population care management depends upon the
comparison of individual data against standards from large scale populations and national medical evidence protocols
How does the introduction of molecular diagnostic testing impact the integrated model, the use of team based care and the use of data?
HIMSS Turkey Presentation
Molecular Diagnostic Testing Impact • As medicine gains greater focus on individual
based care via genomics, will practices become narrower sliced reflections of consumers seeking help based upon their projected disease states
• Centers of specialized prevention?
• When do Primary Care Physicians turn to specialist to focus treatment based on the individual protein levels of cells based on genetic preferences and influences?
HIMSS Turkey Presentation
Types of Genetic Testing Physicians are using
• There are a number of different types of genetic tests available today, including: • Diagnostic testing • Predictive and pre-symptomatic genetic • Carrier testing • Prenatal testing • Pre-implantation genetic testing • Newborn screening • Pharmacogenetic testing • Research genetic testing
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HIMSS Turkey Presentation
Example of Testing for Cardiomyopathy
• In some cases genetic testing may be used to diagnose an inherited cardiac disease. However, in most cases genetic testing is used to help determine which family members could develop the heart problems and which family members will not develop those heart problems. • This allows for focus on an extended patient
population.
HIMSS Turkey Presentation
Success Story of Patient and ROI
• Prevention is a positive investment for Hospitals • Focus on patients before admittance • Keeps beds available for patients who need
critical services • Genomic testing expands patient engagement to
the full family capturing needs for deeper testing • Partnership organizations limit sizable investment
in lab equipment.
14
HIMSS Turkey Presentation
How Promedio works to Support Hospitals.
• Primary and Secondary level testing for variation can be handled by hospital and Promedio • Extension of variation analysis and whole genome
sequencing, beyond primary results, needs rigorous clinical interpretation of sequence information • Samples can be further analyzed by a world leading
authority and compared against a significant data sample.
15
HIMSS Turkey Presentation
Innovations sails until
HIMSS Turkey Presentation
Innovations sails until the anchor of culture and regulation sets in……
HIMSS Turkey Presentation
The advancements of innovation must coincide with regulations The role of government is to balance reimbursement policy between the expectations of innovation and rewarding of entrenched interest.