PERSONAL INFORMATION Eric John Threlfall · PERSONAL INFORMATION Eric John Threlfall ... EU-funded EURLOP and EU-LabCAT projects ... antimicobial drug resistance,

Curriculum vitae

PERSONAL INFORMATION Eric John Threlfall

WORK EXPERIENCE

October 1969–September 2012 Director, laboratory of Enteric Pathogens 2003-2010Public Health Laboratory Service / Health Protection Agency (United Kingdom)

Overall responsibility for all activities of HPA Laboratory of Enteric Pathogens, which is the National Reference Centre for England and Wales for bacterial pathogens from cases of human infection

June 2008–August 2010 Project Director, MedVetNet, 2008-2010Health Protection Agency (United Kingdom)

Overall responsibility for co-ordination of MedVetNet-funded activities undertaken by ca. 400 scientistsin 15 institutes (medical and veterinary) in 10 EU countries.

September 2010–August 2013 Programme manager, EU-funded EURLOP and EU-LabCAT projectsHealth Protection Agency (United Kingdom)

Co-ordination of EU-funded EURLOP and EU-labCAT projects, including liaison with heads of nationalreference laboratories in all EU-27 countries

EDUCATION AND TRAINING

October 1963–July 1969 BSc Honours First ClassUniversity of Wales (United Kingdom)

Applied Botany and Biochemistry

October 1966–October 1969 PhDUniversity of Leicester (United Kingdom)

Microbial Genetics

ADDITIONAL INFORMATION

Expertise Enteric microbiology, Microbial genetics, antimicobial drug resistance, molecular epidemiology, microbial risk assessment

Publications E J THRELFALL BSc; PhD

PUBLICATIONS

1. Threlfall, E.J. & Holland, I.B. (1968) Identification of closely linked loci controlling UV sensitivity and refractivity to colicin E2 in Escherichia coli K12. Proceedings of the Society for General Microbiology 53: 1

2. Holland, I.B. & Threlfall, E.J. (1969) Identification of closely linked loci controlling ultraviolet sensitivity and refractivity to colicin E2 in Escherichia coli K12. Journal of Bacteriology 97: 91-96.

3. Threlfall, E.J. (1969) Genetical and physiological studies into the basis of colicin E2 susceptibility in Escherichia coli K12. Ph.D Thesis, University of Leicester. 1969.

4. Holland, I.B., Threlfall, E.J., Holland, E.M., Darby, V. & Samson, A.C.R. (1970) Mutants of Escherichia coli with altered surface properties which are refractory to colicin E2, sensitive to ultravioletlight, and which can also show recombination deficiency, abortive growth of bacteriophage and filament formation. Journal of General Microbiology 62: 371-382.

5. Threlfall, E.J. & Holland, I.B. (1970) Co-transduction with serB of a pleiotropic mutation affecting colicin E2 refractivity, ultra-violet sensitivity, recombination proficiency and surface properties of Escherichia coli K12. Journal of General Microbiology 62: 383-391.

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Curriculum vitae Eric John Threlfall

6. Anderson, E.S. & Threlfall, E.J. (1970) Change of host range in a resistance factor. Genetical Research 16: 207-214.

7. Anderson, E.S., Threlfall, E.J., Carr, J.M. & Savoy, L.G. (1973) Bacteriophage restriction in Salmonella typhimurium by R factors and transfer factors. Journal of Hygiene 72: 619-631.

8. Anderson, E.S. & Threlfall, E.J. (1974) The characterization of plasmids in the enterobacteria. Journal of Hygiene 72: 471-487.

9. Threlfall, E.J. & Oliver, W.T. (1974) Drug resistance in an animal-human outbreak of Salmonella typhimurium. Proceedings of the Eighth International Congress of Chemotherapy, Athens. pp 23-24. 1974.

10. Anderson, E.S., Threlfall, E.J., Carr, J.M. & Frost, J.A. (1974) Transferable drug resistance in salmonellae in South and Central America. Proceedings of the Society for General Microbiology 1: 66.

11. Threlfall, E.J., Frost, J.A., Carr, J.M. & Anderson, E.S. (1975) Group H1 R factors in Salmonella typhimurium from South-east Asia. Proceedings of the Society for General Microbiology 2: 64.

12. Anderson, E.S., Threlfall, E.J., Frost, J.A. & Carr, J.M. (1975) Transferable drug resistance in animal and human infection with new phage types of Salmonella typhimurium. Proceedings of the Society for General Microbiology 2: 64.

13. Carr, J.M., Frost, J.A., Threlfall, E.J., Savoy, L.G. & Anderson, E.S. (1975) The distribution of groupH2 R factors in Salmonella typhimurium. Proceedings of the Society for General Microbiology 2: 65.

14. Threlfall, E.J., Carr, J.M. & Anderson, E.S. (1976) Compatibility relations of resistance plasmids in Salmonella typhimurium of Middle Eastern origin. Proceedings of the Society for General Microbiology3: 88.

15. Threlfall, E.J. (1976) Resistance to antibacterial drugs in Escherichia coli from imported carcass meat. In: Proceedings of the Standing Conference on Food and Environmental Microbiology, 1976. Public Health Laboratory Service. pp 10-14.

16. Anderson, E.S., Threlfall, E.J., Carr, J.M., McConnell, M.M. & Smith, H.R. (1977) Clonal distribution of resistance plasmid-carrying Salmonella typhimurium, mainly in the Middle East. Journal of Hygiene 79: 425-488.

17. Threlfall, E.J., Ward, L.R. & Rowe, B. (1978) Epidemic spread of a chloramphenicol-resistant strain of Salmonella typhimurium phage type 204 in bovine animals in Britain. Veterinary Record 103: 438-440.

18. Threlfall, E.J., Ward, L.R. & Rowe, B. (1978) The spread of multiresistant strains of Salmonella typhimurium phage types 204 and 193 in Britain. British Medical Journal 6143: 997-998.

19. Hall, M.L.M., Threlfall, E.J., Rowe, B., Pinegar, J.A. & Gibson, G.L. (1978) Lactose-fermenting Salmonella indiana from turkeys in Britain. Lancet ii: 1197-1198.

20. Threlfall, E.J., Ward, L.R. & Rowe, B. (1979) Chloramphenicol-resistant Salmonella typhimurium. Veterinary Record 104: 60-61.

21. Threlfall, E.J., Ward, L.R. & Rowe, B. (1979) Plasmid-mediated antimicrobial drug resistance in Salmonella dublin in food animals. Veterinary Record 105: 20-21.

22. Rowe, B., Threlfall, E.J., Ward, L.R. & Ashley, A.S. (1979) International spread of multiresistant strains of Salmonella typhimurium phage types 193 and 204 from Britain to Europe. Veterinary Record105: 468-469.

23. Threlfall, E.J. & Rowe, B. (1980) Chloramphenicol-resistant Salmonella typhi Vi-phage type E1. WHO Weekly Epidemiological Record 11: 81.

24. Threlfall, E.J., Ward, L.R., Ashley, A.S. & Rowe, B. (1980) Plasmid-encoded trimethoprim resistance in multiresistant epidemic Salmonella typhimurium phage types 204 and 193 in Britain. British Medical Journal 1: 1210-1211.

25. Rowe, B., Frost, J.A., Threlfall, E.J. & Ward, L.R. (1980) The spread of a multiresistant clone of Salmonella typhimurium in South East Asia and the Middle East. Lancet i: 1070-1071.

26. Threlfall, E.J., Rowe, B. & Huq, I. (1980) Plasmid-encoded multiple antibiotic resistance in Vibrio cholerae El Tor from Bangladesh. Lancet i: 1247-1248.

27. Rowe, B. & Threlfall, E.J. (1980) Multiply antibiotic-resistant O-group Vibrio cholerae. WHO Weekly Epidemiological Record 30: 291-293.

28. Threlfall E.J. (1980) Antibiotic resistance - whose fault? : the occurrence and spread of multiresistant strains of Salmonella typhimurium phage types 204 and 193 in Britain. Veterinary Record 107: 213.

29. Willshaw, G.A., Threlfall, E.J., Ward, L.R., Ashley, A.S. & Rowe, B. (1980) Plasmid studies of drug-



resistant epidemic strains of Salmonella typhimurium belonging to phage types 204 and 193. Journal of Antimicrobial Chemotherapy 6: 763-773.

30. Threlfall, E.J. (1980) Salmonella, plasmids linked to strains; In: Global deployment of antibiotic resistance genes. Proceedings of the 11th International Congress of Chemotherapy, 1980. Vol 1. pp 46-49.

31. Rowe, B. & Threlfall, E.J. (1981) Multiple antimicrobial drug resistance in enteric pathogens. Journal of Antimicrobial Chemotherapy 7: 1-3.

32. Rowe, B. & Threlfall, E.J. (1981) Multiply-resistant clones of Salmonella typhimurium in Britain: epidemiological and laboratory aspects. In: Molecular Biology, Pathogenicity and Ecology of Bacterial Plasmids. Editors: Levy, S.B., Clowes, R.C. & Koenig, E.L. Plenum Press, New York, 1981. pp 567-573.

33. Frost, J.A., Rowe, B., Vandepitte, J. & Threlfall, E.J. (1981) Plasmid characterization in the investigation of an epidemic caused by multiply-resistant Shigella dysenteriae type 1 in Central Africa. Lancet ii: 1074-1076.

34. Threlfall, E.J. & Ward, L.R. (1981) The occurrence and spread of multiresistant clones of Salmonella typhimurium in Britain. What’s New 10, 5-6. PHLS, 1981.

35. Gross, R.J., Threlfall, E.J., Ward, L.R. & Rowe, B. (1982) Antibiotic resistance among infantile enteropathogenic Escherichia coli and E. coli from cerebrospinal fluid. Society for General Microbiology Quarterly 8: 7.

36. Frost, J.A., Threlfall, E.J. & Rowe, B. (1982) Plasmid-determined antibiotic resistance in epidemic strains of Shigella dysenteriae 1. Society for General Microbiology Quarterly 8: 8.

37. Threlfall, E.J., Alim, A.R.M.A. & Rowe, B. (1982) Plasmids in multiply antibiotic resistant strains of Vibrio cholerae El Tor. Society for General Microbiology Quarterly 8: 10

38. Threlfall, E.J. & Rowe, B. (1982) Vibrio cholerae El Tor acquires plasmid-encoded resistance to gentamicin. Lancet i: 42.

39. Chau, P.Y., Ling, J., Threlfall, E.J. & Im, S.W.K. (1982) Genetic instability of R plasmids in relation to the shift of drug resistance in Salmonella johannesburg. Journal of General Microbiology 128: 239-245.

40. Threlfall E.J. (1982) Multiresistant epidemic strains of Salmonella typhimurium in Britain. In: Resistance and Pathogenic Plasmids. Editors: Pohl, P., Leunen, J. National Institute for Veterinary Research, Brussels. 1982. pp 103-114.

41. Threlfall, E.J., Ward, L.R., Rowe, B. & Robins-Browne, R. (1982) Acquisition of resistance by Salmonella typhi in vivo: the importance of plasmid characterization. Lancet i: 740.

42. Frost, J.A., Rowe, B., Ward, L.R. & Threlfall, E.J. (1982) Characterization of resistance plasmids and carried phages in an epidemic clone of multi-resistant Salmonella typhimurium in India. Journal of Hygiene 88: 193-204.

43. Threlfall, E.J. (1982) Drug resistance in salmonellas. Lancet i: 1391-1392. (Editorial).

44. Gross, R.J., Ward, L.R., Threlfall, E.J., King, H.C. & Rowe, B. (1982) Drug resistance among infantile enteropathogenic Escherichia coli strains isolated in the United Kingdom. British Medical Journal 285: 472-473.

45. Ward, L.R., Rowe, B. & Threlfall, E.J. (1982). The incidence of trimethoprim resistance in salmonellae isolated in Britain: a twelve year study. Lancet i: 705-706.

46. Threlfall, E.J., Bheem Bhat, M. & Sharma, K.B. (1982) Genetic analysis of plasmids coexisting in Salmonella newport isolated from a salmonellosis outbreak in Delhi. Indian Journal of Medical Research 76: 358-363.

47. Threlfall, E.J. & Rowe, B. (1982) Cholera surveillance - emergence of gentamicin-resistant strains of Vibrio cholerae O1 biotype El Tor. WHO Weekly Epidemiological Record 3: 19.

48. Threlfall, E.J., Frost, J.A., King, H C. & Rowe, B. (1983) Plasmid-encoded trimethoprim resistance in salmonellas isolated in Britain between 1970 and 1981. Journal of Hygiene 90: 55-60.

49. Gross, R.J., Ward, L.R., Threlfall, E.J., Cheasty, T & Rowe, B. (1983) Drug resistance among Escherichia coli strains isolated from cerebrospinal fluid. Journal of Hygiene 90: 195-198.

50. Threlfall, E.J., Hall, M.L.M. & Rowe, B. (1983) Lactose-fermenting salmonellae in Britain. FEMS Microbiology Letters 17: 127-130.

51. Glass, R.I., Huq, M.I., Lee, J.V., Threlfall, E.J., Khan, M.R., Alim, A.R.M.A., Rowe, B. & Gross, R.J.(1983) Plasmid-borne multiple drug resistance in Vibrio cholerae serogroup O1, biotype El Tor: evidence for a point source outbreak in Bangladesh. Journal of Infectious Diseases 147: 204-209.



52. Robins-Browne, R.M., Rowe, B., Ramsaroop, R., Naran, A.D., Threlfall, E.J., Ward, L.R., Lloyd, D.A. & Mickel, R.E. (1983) A hospital outbreak of multiresistant Salmonella typhimurium belonging to phage type 193. Journal of Infectious Diseases 147: 210-216.

53. Gross, R.J. & Threlfall, E.J. (1983) Mechanisms in enteropathogenic Escherichia coli diarrhoea. Lancet i: 1254-1256 (Editorial).

54. Frost, J.A., Threlfall, E.J. & Willshaw, G.A. (1983) Methods of studying transferable resistance to antibiotics in vitro. In: Antibiotics: Methods of Assessing Antimicrobial Resistance and the Occurence of Resistance. Eds:, Russell, A.P., Quesnel, L.B. SAB Technical Series 1983. Academic Press. pp 265-284.

55. Threlfall, E.J., Ward, L.R. & Rowe, B. (1983) The use of phage typing and plasmid characterizationin studying the epidemiology of multiresistant Salmonella typhimurium. In: Antibiotics: Methods of Assessing Antimicrobial Resistance and the Occurrence of Resistance. Eds: Russell, A.P., Quesnel, L.B. SAB Technical Series 1983. Academic Press. pp 285-297.

56. Threlfall, E.J. (1983) Phage therapy. Lancet ii: 1287-1288.

57. Threlfall, E.J., Frost, J.A. & Rowe, B. (1983) Multiresistant intestinal pathogens in developing countries. APUA Newsletter 1: 3-7.

58. Threlfall, E.J., Rowe, B., Ferguson, J.L. & Ward, L.R. (1983) Gentamicin-resistant Salmonella typhimurium. Veterinary Record 113: 627.

59. Rowe, B. & Threlfall, E.J. (1984) Drug resistance in gram negative aerobic bacilli. British Medical Bulletin 40: 68-76.

60. Gross, R.J., Threlfall, E.J., Ward, L.R. & Rowe, B. (1984) Drug resistance in Shigella dysenteriae, Sh. flexneri and Sh. boydii in England and Wales: increasing incidence of resistance to trimethoprim. British Medical Journal 288: 784-786.

61. Threlfall, E.J. & Rowe, B. (1984) Antimicrobial resistance in salmonellae in Britain - a real threat to public health? In: Antimicrobials and Agriculture. 4th International Symposium on Antibiotics in Agriculture: Benefits and Malefits. Editor, Woodbine, M. Butterworths, London. 1984. pp 513-524.

62. Threlfall, E.J. (1984) The evolution of R plasmids in Salmonella typhimurium in Britain. In: Priority Aspects of Salmonellosis Research. Editor, Larsen, E. Office for Official Publications of the European Communities. 1984. pp 287-292.

63. Threlfall, E.J. & Rowe, B. (1985) Plasmid-mediated antibiotic resistance in Salmonella typhimurium in Britain: recent trends and new observations. In: Proceedings of the International Symposium on Salmonella. Editor, Snoyenbos, G.H. American Association of Avian Pathologists. University of Pennsylvania, U.S.A. 1985. pp 358-559.

64. Gross, R.J. & Threlfall, E.J. (1985) Escherichia coli O142: H6; a drug-resistant enteropathogenic clone? Journal of Hygiene 94: 181-191.

65. Threlfall, E.J., Ferguson, J.L., Ward, L.R. & Rowe, B. (1985) Resistance to gentamicin and related aminoglycosides in Salmonella typhimurium endemic in cattle in Britain. Society for General Microbiology Quarterly 12: 7.

66. Threlfall, E.J. Resistance to growth promoters. In: Criteria and Methods for the Microbiological Evaluation of Growth Promotors in Animal Feeds. Editors, Helmuth, R., Bulling, E. Institut fur Veterinarmedizin des Bungesundheitsamts, Berlin. 1985. pp 126 141.

67. Threlfall, E.J., Rowe, B., Ferguson, J.L. & Ward, L.R. (1985) Increasing evidence of resistance to gentamicin and related amino glycosides in Salmonella typhimurium phage type 204c in England, Wales and Scotland. Veterinary Record 117: 355 357.

68. Rowe, B. & Threlfall, E.J. (1986) Antibiotic resistance in Salmonella. PHLS Microbiology Digest 3, 23 25.

69. Threlfall, E.J., Hall, M.L.M. & Rowe, B. (1986) Salmonella gold coast from outbreaks of food poisoning in the British Isles can be differentiated by plasmid profiles. Journal of Hygiene 97: 115 122.

70. Threlfall, E.J., Hall, M.L.M., Ward, L.R. & Rowe, B. (1986) Use of plasmid profiling in investigating outbreaks of Salmonella food-poisoning in Britain. IUMS XIV International Congress of Microbiology, Manchester: Abstract. P.G5-60.

71. Threlfall, E.J., Ward, L.R. & Rowe, B. (1986) R plasmids in Salmonella typhimurium in the United Kingdom. Journal of Antimicrobial Chemotherapy 18: Supplement C, 175 177.

72. Threlfall, E.J., Rowe, B., Ferguson, J.L. & Ward, L.R. (1986) Characterization of plasmids conferring resistance to gentamicin and apramycin in strains of Salmonella typhimurium phage type 204c isolated in Britain. Journal of Hygiene 97: 419 426.

73. Threlfall, E.J., Rowe, B. & Ward, L.R. (1987) Increase in prevalence of a neomycin/kanamycin



sensitive variant of Salmonella typhimurium DT204 in cattle in Britain. Veterinary Record 15: 366 367.

74. Rowe, B., Threlfall, E.J. & Ward, L.R. (1987) Does chloramphenicol remain the drug of choice for typhoid? Epidemiology and Infection 98: 379 383.

75. Hinton, M., Meade, G., Threlfall, E.J., Rowe, B., Woodward, M. & Wray, C. (1989) Experimental Salmonella enteritidis infection in chickens. Veterinary Record 124: 223.

76. Johnson, A.P, Woodford, N. Threlfall, E.J. & George, R.C. (1989) Resistance to a veterinary antibiotic (apramycin) causing cross resistance to gentamicin in human clinical isolates of enterobacteriaceae. Journal of Medical Microbiology 28: xvi xvii.

77. Chart, H., Threlfall, E.J. & Rowe, B. (1989) Virulence of Salmonella enteritidis phage type 4 is related to possession of a 38 MDa plasmid. FEMS Microbiology Letters 58: 299 304.

78. Threlfall, E.J., Brown, D., Rowe, B. & Ward, L.R. (1989) Multiply resistant strains of Salmonella typhimurium in poultry. Veterinary Record 20: 538.

79. Threlfall, E.J. (1989) Antibiotic usage in animal husbandry is drug resistance a real problem? In: Agricultural Chemicals in the Food Chain: Proceedings of the 11th meeting of the Forum on Food and Health. Journal of the Royal Society of Medicine 82: 311 315.

80. Threlfall, E.J., Rowe, B. & Ward, L.R. (1989) Subdivision of Salmonella enteritidis phage types by plasmid profile typing. Epidemiology and Infection 102: 459 466.

81. Chart, H., Rowe, B., Threlfall, E.J. & Ward, L.R. (1989) Conversion of Salmonella enteritidis phagetype 4 to phage type 7 involves loss of lipopolysaccharide with concomitant loss of virulence. FEMS Microbiology Letters 60: 37 40.

82. Joyce, R., O'Sullivan, D.G., Strong, C., Rowe, B., Hall, M.L.M. & Threlfall, E.J. (1990) A national outbreak of Salmonella gold coast. PHLS Communicable Disease Report 90/04: 3 4.

83. Threlfall, E.J. & Frost, J.A. (1990) The identification, typing and fingerprinting of Salmonella: laboratory aspects and epidemiological applications. Journal of Applied Bacteriology 68: 5 16.

84. Threlfall, E.J., Frost, J.A., Ward, L.R. & Rowe, B. (1990) Plasmid profile typing can be used to subdivide phage type 49 of Salmonella typhimurium in outbreak investigations. Epidemiology and Infection 104: 243 251.

85. Threlfall, E.J., Hall, M.L.M., Frost, J.A. & Rowe, B. (1990) A plasmid typing scheme for Salmonella kedougou. In: Proceedings of the 2nd International Meeting on Bacterial Epidemiological Markers. Publ: Ascent Ltd, Athens. 1990. p 171.

86. Hinton, M., Threlfall, E.J. & Rowe, B. (1990) The invasive potential of Salmonella enteritidis phage types for young chickens. Letters in Applied Microbiology 10: 237 239.

87. Hinton, M., Threlfall, E.J. & Rowe, B. (1990) The invasiveness of different strains of Salmonella enteritidis phage type 4 for young chickens. FEMS Microbiology Letters 70: 193 196.

88. Agodi, A., Jones, C., Threlfall, E.J., D'Angelo, M. & Marranzano, M. (1990) Molecular characterization of trimethoprim resistance in Shigella sonnei in Sicily. Epidemiology and Infection 105:21 27.

89. Ward, L.R., Threlfall, E.J. & Rowe, B. (1990) Multiple drug resistance in salmonellas isolated from humans in England and Wales: a comparison of 1981 with 1988. Journal of Clinical Pathology 43: 563566.

90. Threlfall, E.J., Brown, D.J., Ward, L.R. & Rowe, B. (1990) Occurrence of S. typhimurium DT204c in poultry in England and Wales. Veterinary Record 127: 234.

91. Rowe, B., Ward, L.R. & Threlfall, E.J. (1990) Spread of multiresistant Salmonella typhi. Lancet 336: 1065 1066.

92. Joseph, C.A., Mitchell, E.N., Cowden, J.M., Bruce, J.C., Threlfall, E.J., Hine, C.E., Wallis, R., & Hall, M.L.M. (1991) A national outbreak of Salmonella manchester infection. Communicable Disease Report 1: 16 19.

93. Brown, D.J., Threlfall, E.J. & Rowe, B. (1991) Instability of multiple drug resistance plasmids in Salmonella typhimurium from poultry. Epidemiology and Infection 106: 247 257.

94. Woodford, N., Johnson A.P. & Threlfall, E.J. (1991) Methods for the extraction and analysis of plasmid DNA. In: Plasmid analysis: an introductory workshop. (Course Manual). Central Public HealthLaboratory. 1991.

95. Rowe, B., Ward, L.R. & Threlfall, E.J. (1991) Treatment of multiresistant typhoid fever. Lancet 337: 1422.

96. Chart, H., Threlfall, E.J. & Rowe, B. (1991) Virulence studies of Salmonella enteritidis phage types.Letters in Applied Microbiology 12: 188 191.



97. Stanley, J., Jones, C.S. & Threlfall, E.J. (1991) Evolutionary lines among Salmonella enteritidis phage types are identified by insertion sequence IS200 distribution. FEMS Microbiology Letters 82: 8390.

98. Threlfall, E.J., Rowe, B. & Ward, L.R. (1991) Occurrence and treatment of multi resistant Salmonella typhi in the UK. PHLS Microbiology Digest 8: 56 91.

99. Hinton, M., Mohammed, M.D., Benton, J & Threlfall, E.J. (1991) Transfer of an IncN AST plasmid in the intestine of chick and in poultry feed. In: Prevention and Control of Potentially Pathogenic Microorganisms in Poultry and Poultry Meat Processing. 3. Salmonella Colonization in Poultry. Eds: Ducatelle, R., Haesebrouck, F., Mulder, R.W.A.W. Centre for Poultry Research and Information Services. Flair No. 6/Cost No. 906, The Netherlands, 1991.

100. Threlfall, E.J., Hall, M.L.M. & Rowe, B. (1992) Salmonella bacteraemia in England and Wales, 1981 1990. Journal of Clinical Pathology 45: 34 36.

101. Threlfall, E.J., Hall, M.L.M. & Rowe, B. (1992) Increase in Salmonella berta infections in humans in England and Wales from 1986 to 1990: association with imported poultry. European Journal of Epidemiology 8: 27 33.

102. Stanley, J., Goldsworthy, M. & Threlfall, E.J. (1992) Molecular phylogenetic typing of pandemic isolates of Salmonella enteritidis. FEMS Microbiology Letters 90: 153 160.

103. Stanley, J., Burnens, A.P., Threlfall, E.J., Chowdry, N., Goldsworthy, M. (1992) Genetic relationships among strains of Salmonella enteritidis in a national epidemic (Switzerland). Epidemiology & Infection 108: 213 220.

104. Threlfall, E.J., Rowe, B. & Ward, L.R. (1992) Recent changes in the occurrence of antibiotic resistance in Salmonella isolated in England and Wales. PHLS Microbiology Digest 9: 69 71.

105. Threlfall, E.J. (1992). Antibiotics and the selection of food borne pathogens. In: Ecosystems: Microbes: Food. Journal of Applied Bacteriology Symposium Supplement 73: 96S 102S.

106. Rowe, B., Ward, L.R., Threlfall, E.J. (1992) Ciprofloxacin and typhoid fever. Lancet 339: 740.

107. Stanley, J., Chowdry, N., Powell, N., Threlfall, E.J. (1992) Chromosomal genotypes (evolutionary lines) of Salmonella berta. FEMS Microbiology Letters 95: 247-252.

108. Threlfall, E.J. & Ward, L.R. (1992) Antibacterial resistance in Salmonella. In: AVCPT. ProceedingsNo. 14. Association for Veterinary Clinical Pharmacology and Therapeutics, 1992. pp 257-264.

109. Threlfall, E.J., Ward, L.R., Rowe, B., Raghupathi, V., Chandrasekaren, V., Vandepitte, J. & Lemmen, P. (1992) Widespread occurence of multiple drug resistant Salmonella typhi in India. European Journal of Clinical Microbiology & Infectious Diseases 11: 990-993.

110. Threlfall, E.J., Ward, L.R & Rowe, B. (1992) Antibiotic resistance in Salmonella isolated from humans in the UK in 1990: epidemiological and molecular aspects. In: "Prevention and Control of Potentially Pathogenic Microorganisms in Poultry and Poultry Meat Processing". 7. The role of antibiotics in the control of foodborne pathogens. Editors: Hinton, M.H., Mulder, R.W.A.W. COVP-DLO, Het Spelderholt. The Netherlands, 1992. pp 31-36.

111. Chart, H., Threlfall, E.J., Ward, L.R. & Rowe, B. (1993). Unusual expression of lipopolysaccharideby strains of Salmonella enteritidis phage type 30. Letters in Applied Microbiology 16, 87-90.

112. Edwards, G.S.F., Curran, E.T., McCartney, A.C., Paterson, K.R., Girdwood, R.W.A., Threlfall, E.J. & Ward, L.R. (1993). Nosocomial salmonellosis: hospital outbreak caused by a highly communicable strain of Salmonella typhimurium. CDR Review 3: R40-42.

113. Brown, D.J., Threlfall, E.J., Hampton, M.D. & Rowe, B. (1993). Molecular characterization of plasmids in Salmonella enteritidis phage types. Epidemiology and Infection 110: 209-216.

114. Chowdry, N., Threlfall, E.J., Rowe, B. & Stanley, J. (1993). Genotype analysis of faecal and bloodisolates of Salmonella dublin from humans. Epidemiology and Infection 110: 217-225.

115. Riley, P., Threlfall, E.J., Cheasty, T., Wooldridge, K.G., Williams, P.H. & Phillips, I. (1993) Occurrence of FIme plasmids in multiply antimicrobial resistant Escherichia coli isolated from urinary tract infections. Epidemiology and Infection 110: 459-468.

116. Stanley, J., Chowdry-Baquar, N. & Threlfall, E.J. (1993) Genotypes and phylogenetic relationships of Salmonella typhimurium are defined by molecular fingerprinting of IS200 and 16S rrn loci. Journal of General Microbiology 139: 1133-1140.

117. Threlfall, E.J., Chart, H., Ward, L.R., De Sa, J.D.H. & Rowe, B. (1993). Interrelationships betweenstrains of Salmonella enteritidis belonging to phage types 4, 7, 7a, 13, 13a, 23, 24 and 30. Journal of Applied Bacteriology 75: 43-48.

118. Simpson, J., Threlfall, E.J., Derrick, G. & Mellersh, A. (1993). An unusual case of multiple enteric infections. Journal of Infection 27: 103-105.



119. Threlfall, E.J. & Chart, H. (1993). Interrelationships between strains of Salmonella enteritidis. (Special article). Epidemiology and Infection 111: 1-8.

120. McCartney, A.C., Edwards, G.F.S., Curran, E.T. & Threlfall, E.J. (1993) Transmission of Salmonella from health care workers. Journal of Hospital Infection 24: 157.

121. Threlfall, E.J., Rowe, B. & Ward, L.R. (1993) Changing trends in the occurrence of drug resistance in Salmonella isolated from humans in England and Wales. In: Biology of Salmonella. Editors: Cabello P, Hormachae C, Mastroeni P, Bonina L. Plenum Press, New York. 1993. pp 1-7

122. Rowe, B., Threlfall, E.J. & Ward, L.R. (1993) The problem of multiresistant Salmonella typhi use of molecular markers in epidemiology. In: Biology of Salmonella. Editors: Cabello, F., Hormachae C., Mastroeni, P., Bonina, L. Plenum Press, New York. 1993. pp 9-13.

123. Edwards, G.F., Curran, E.T., McCartney, A.C., Paterson, K.R., Girdwood, A., Threlfall, E.J. & ward, L.R. (1993) Nosocomial salmonellosis. Communicable Disease Report CDR Review 3: R40-R41.

124. Mourad, A.S., Metwally, M., Nour El Deen, A., Threlfall, E.J., Rowe, B., Mapes, T., Hedstrom, R., Bourgeois, A.L. & Murphy, J.R. (1993) Multiple-drug-resistant Salmonella typhi. Clinical Infectious Diseases 17: 135-136.

125. Threlfall, E.J., Rowe, B. & Ward, L.R. (1993) A comparison of multiple drug resistance in salmonellas from humans and food animals in England and Wales, 1981 and 1990. Epidemiology and Infection 111: 189-197.

126. Baquar, N., Threlfall, E.J., Rowe, B. & Stanley, J. (1993) Molecular subtyping within a single Salmonella typhimurium phage type, DT204c, with a PCR-generated probe for IS200. FEMS Microbiology Letters 112: 217-222.

127. Threlfall, E.J., Said, B., Rowe, B. & Dávalos-Pérez, A. (1993) Emergence of multiple drug resistance in Vibrio cholerae El Tor from Ecuador. Lancet 342: 1173.

128. Torre, E., Threlfall, E.J., Hampton, M.D., Ward, L.R., Gibert, I. & Rowe, B. (1993) Characterizationof Salmonella virchow phage types by plasmid profile and IS200 distribution. Journal of Applied Bacteriology 75: 435-440.

129. Threlfall, E.J., Torre, E., Ward, L.R. & Gibert, I. (1993) Insertion sequence IS200 can differentiate drug-resistant and drug-sensitive Salmonella typhi of Vi-phage types E1 and M1. Journal of Medical Microbiology 39: 454-458.

130. Synott, M., Morse, D.L., Maguire, H., Majid, F., Plummer, M., Leicester, M. & Threlfall, E.J. & Cowden, J. (1993) An outbreak of Salmonella mikawasima associated with doner kebabs. Epidemiology and Infection 111: 473-481.

131. Irwin, D.J., Rao, M., Ward, L.R. & Threlfall, E.J. (1993) Lessons from a large outbreak of infectionwith Salmonella enteritidis phage type 4 associated with the use of raw shell eggs. Communicable Disease Review 3: R40-R43.

132. Wallace, M.R., Yousif, A.A., Mahroos, G.A., Mapes, T., Threlfall, E.J., Rowe, B. & Hyams, K.C. (1993) Ciprofloxacin versus ceftriaxone in the treatment of multiresistant typhoid fever. European Journal of Clinical Microbiology and Infectious Diseases 12: 907-910.

133. Olsen, J.E., Skov, M.N., Threlfall, E.J. & Brown, D.J. (1994) Clonal lines of Salmonella enterica serotype enteritidis documented by IS200-, ribo-, pulsed field gel electrophoresis and RFLP typing. Journal of Medical Microbiology 40: 15-22.

134. Threlfall, E.J., Hampton, M.D., Chart, H. & Rowe, B. (1994) Identification of a conjugative plasmidcarrying antibiotic resistance and salmonella plasmid virulence (spv) genes in epidemic strains of Salmonella typhimurium. Letters in Applied Microbiology 18: 82-85.

135. Threlfall, E.J., Hampton, M.D., Chart, H. & Rowe, B. (1994) Use of plasmid profile typing for surveillance of Salmonella enteritidis phage type 4 from humans, poultry and eggs. Epidemiology and Infection 112: 25-32.

136. Baquar, N., Threlfall, E.J., Rowe, B. & Stanley, J. (1994) Phage type DT 193 of Salmonella typhimurium contains different chromosomal genotypes and multiple IS200 profiles. FEMS Microbiology Letters 115: 291-296

137. Johnson, A.P., Burns, L., Woodford, N., Threlfall, E.J., Naidoo, J., Cooke, E.M. & George, R.C. (1994) Gentamicin resistance in clinical isolates of Escherichia coli and Klebsiella pneumoniae encoded by genes of veterinary origin. Journal of Medical Microbiology 40: 221-226.

138. Threlfall, E.J., Torre, E., Ward, L.R., Dávalos-Pérez, A., Rowe, B. & Gibert, I. (1994) Insertion sequence IS200 fingerprinting of Salmonella typhi: an assessment of epidemiological applicability. Epidemiology and Infection 112: 253-261.

139. Threlfall, E.J., Frost, J.A., Ward, L.R. & Rowe, B. (1994) Epidemic in cattle of S typhimurium DT



104 with chromosomally-integrated multiple drug resistance. Veterinary Record 134: 577.

140. Vatopoulos, A.C., Mainas, E., Balis, E., Threlfall, E.J., Kanelopoulou, M., Kalapothaki, V., Malamou-Lada, E. & Legakis, N.J. (1994) Molecular epidemiology of ampicillin-resistant clinical isolates of Salmonella enteritidis. Journal of Clinical Microbiology 32: 1322-1325.

141. Powell, N.G., Threlfall, E.J., Chart, H. & Rowe, B. (1994) Subdivision of Salmonella enteritidis PT 4 by pulsed-field gel electrophoresis: potential for epidemiological surveillance. FEMS Microbiology Letters 119: 193-198.

142. Woodford, N., Johnson, A.P., Threlfall, E.J. (1994) Extraction and fingerprinting of bacterial plasmids. In: Methods in Practical Laboratory Bacteriology. Editor: Chart, H. CRC Press Inc, New York. 1994, pp 93-105.

143. Wall, P.G., Morgan, D., Lamden, K., Ryan, M., Griffin, M., Threlfall, E.J., Ward, L.R. & Rowe, B. (1994) A case-control study of infection with an epidemic strain of multiresistant Salmonella typhimurium DT 104 in England and Wales. Communicable Disease Report 4: R130-R135.

144. Erdem, B., Threlfall, E.J., Schofield, S.L., Ward, L.R. & Rowe, B. (1994) Plasmid profile typing provides a method for the differentiation of strains of Salmonella enteritidis phage type 4 isolated in Turkey. Letters in Applied Microbiology 19: 265-267.

145. Threlfall, E. J., Powell, N.G. & Rowe, B. (1994) Differentiation of salmonellas by molecular methods for epidemiological investigations. PHLS Microbiology Digest 11: 199-202.

146. Agodi, A., Marranzano, M., Jones, C.S. & Threlfall, E.J. (1995) Molecular characterization of trimethoprim resistance in salmonellas isolated in Sicily, 1985 -1988. European Journal of Epidemiology 11: 33-38.

147. Hampton, M.D., Threlfall, E.J., Frost, J.A., Ward, L.R. & Rowe, B. (1995) Salmonella typhimuriumDT 193: differentiation of an epidemic phage type by antibiogram, plasmid profile, plasmid fingerprint and salmonella plasmid virulence (spv) gene probe. Journal of Applied Bacteriology 78: 402-408.

148. Powell, N.G., Threlfall, E.J., Chart, H., Schofield, S.L. & Rowe, B. (1995) Correlation of change in phage type with pulsed field profile and 16S rrn profile in Salmonella enteritidis phage types 4, 7 and 9a. Epidemiology and Infection 114: 403-411.

149. Wall, P.G., Davis, S., Threlfall, E.J. & Ward, L.R. (1995) Chronic carriage of multidrug resistant Salmonella typhimurium in a cat. Journal of Small Animal Practice 36: 279-281.

150. Threlfall, E.J. & Woodford, N. (1995) Plasmid profile typing and plasmid fingerprinting. In: Methods in Microbiology Volume 46: Diagnostic Bacteriology Protocols. Editors, Howard, J.J., Whitcombe, D. Humana Press Inc., Towata, NJ; 1995. pp 225-236.

151. Wall, P.G., Morgan, D., Lamden, K., Griffin, M. & Threlfall, E.J., Ward, L.R. & Rowe, B. (1995) Transmission of multi-resistant Salmonella typhimurium from cattle to man. Veterinary Record 136: 591-592.

152. Reed, C.S., Barret, S.P., Threlfall, E.J. & Cheasty, T. (1995) Control of infection with multiple antibiotic resistant bacteria in a hospital renal unit: the value of plasmid characterization. Epidemiologyand Infection 115: 61-70.

153. Frost, J.A., Threlfall, E.J. & Rowe, B. (1995) Antibiotic resistance in salmonellas from humans in England and Wales: the situation in 1994. PHLS Microbiology Digest 12: 131-133.

154. Rowe, B., Ward, L.R. & Threlfall, E.J. (1995) Ciprofloxacin-resistant Salmonella typhi in the UK. Lancet 346: 1302.

155. Threlfall, E.J. (1995) Resistant Gut Bacteria. In: Manson's Tropical Diseases, 20th Edition. Editor, Cook, G.C. W.B Saunders. London. pp 864-872.

156. Aabo, S., Olsen, J.E., Threlfall, E.J. & Brown, D.J. (1995) Characterization of non-virulence plasmids with homology to the virulence plasmid of Salmonella dublin. Research in Microbiology 146: 751-759.

157. Rowe, B., Frost, J.A. & Threlfall, E.J. (1995) Antibiotic resistance in non-typhoidal salmonellas from humans in England and Wales in the 10-month period January - October 1995: a comparison with 1994. Veterinary Products Committee 1995; VPC (95) 220.

158. Threlfall, E.J., Ward, L.R., Frost, J.A. & Rowe, B. (1995) Typhoid fever and other salmonellosis: a changing pattern of drug susceptibilities. Southeast Asian Journal of Tropical Medicine and Public Health 26, Supplement 2: 13-16.

159. Threlfall, E.J., Powell, N.G. & Rowe, B. (1995) The identification, typing and fingerprinting of Salmonella: Laboratory aspects and epidemiological applications. Southeast Asian Journal of TropicalMedicine and Public Health, 26, Supplement 2: 217-221.

160. Chart, H., Threlfall, E.J., Powell, N.G. & Rowe, B. (1996) Serum survival and plasmid possession



by strains of Salmonella enteritidis, Salm. typhimurium and Salm. virchow. Journal of Applied Bacteriology 80: 31-36.

161. Threlfall, E.J., Frost, J.A., Ward, L.R. & Rowe, B. (1996) Increasing spectrum of resistance in multiresistant Salmonella typhimurium. Lancet 347: 1053-1054.

162. Threlfall, E.J., Hampton, M.D., Ward, L.R. & Rowe, B. (1996) Application of pulsed-field gel electrophoresis to an international outbreak of Salmonella agona. Emerging Infectious Diseases 2: 130-132.

163. Threlfall, E.J., Frost, J.A., Rowe, B. (1996) Public Health problems associated with the use of antibiotics. In: Recent Advances in Animal Nutrition - 1996. Editors, Garnsworthy, P.C., Wiesman, J., Haresign, W. Nottingham University Press 1996. pp 47-53.

164. Wall, P.G., Threlfall, E.J., Ward, L.R. & Rowe, B. (1996) Multiresistant Salmonella typhimurium DT 104 in cats: a public health risk. Lancet 348: 471.

165. Threlfall E.J., Ridley, A.M., Ward, L.R. & Rowe, B. (1996) Assessment of health risk from Salmonella-based rodenticides. Lancet 348: 616.

166. Threlfall, E.J., Ridley, A.R. & Hampton, M.D. (1996) Technical advances in the bacteriological laboratory: methods for DNA analysis. PHLS Microbiology Digest 13, 138-140.

167. Threlfall, E.J., Hampton, M.D., Schofield S.L., Ward, L.R., Frost, J.A. & Rowe, B. (1996) Epidemiological application of differentiating multiresistant Salmonella typhimurium DT 104 by plasmidprofile. CDR Review 6, R115-159.

168. Lewis, D.A., Paramathasan, R., White, D.G., Neil, L.S., Tanner, A.C., Hill, S.D., Bruce, J.C., Stuart, J.M., Ridley, A.M. & Threlfall, E.J. (1996) Marshmallows cause an outbreak of infection with Salmonella enteritidis phage type 4. CDR Review 6, R183-R186.

169. Ridley, A.M., Punia, P., Ward, L.R., Rowe, B. & Threlfall, E.J. (1996) Plasmid characterisation andpulsed field electrophoretic analysis demonstrate that ampicillin-resistant strains of Salmonella enteritidis phage type 6a are derived from Salm. enteritidis phage type 4. Journal of Applied Bacteriology 81, 613-618

170. Willshaw, G.A., Cheasty, T., Frost, J.A., Threlfall, E J. & Rowe, B. (1996) Antimicrobial resistance of O157 VTEC in England and Wales. Notiziario dell' Istituto Superiore di Sanita. 9, (Suppl.3). EVC news 5; 3-4.

171. Threlfall, E.J., Cheasty, T., Graham, A. & Rowe, B. (1997) High level resistance to ciprofloxacin inEscherichia coli. Lancet 349, 403.

172. Rowe, B, Ward, L.R. & Threlfall, E.J. (1997) Multiresistant Salmonella typhi - a world-wide epidemic. Clinical Infectious Diseases 24 (Suppl 1), S106-S109

173. Threlfall E.J. (with others) in: Public Health Laboratory Service (PHLS) Laboratory of Enteric Pathogens et al. (1997) Preliminary report of an international outbreak of Salmonella anatum infection linked to infant formula milk. Eurosurveillance 2, 22-24

174. Olsen J.E., Skov, M.N., Angen, Ø., Threlfall, E.J. & Bisgaard, M. (1997) Genomic relationships between selected phage types of Salmonella enterica serotype Typhimurium defined by ribotyping, IS200 typing and PFGE. Microbiology 143, 1471-1479

175. Rushdy, A.A., Wall, R., Seng, C., Wall, P.G., Ridley, A.M., Threlfall, E.J. and Ward, L.R. (1997) Application of molecular methods to a nosocomial outbreak of Salmonella enteritidis phage type 4. Journal of Hospital Infection 36, 123-131.

176. Herikstad, H., Hayes, P., Mokhtar, M., Fracaro, M.L., Threlfall, E.J. & Angulo, F.J. (1997) Emerging quinolone-resistant Salmonella in the United States. Emerging Infectious Diseases 3, 371-372.

177. Threlfall, E.J., Ward, L.R., Skinner, J.A. & Rowe, B. (1997) Increase in multiple drug resistance in non-typhoidal salmonellas from humans in England and Wales: a comparison of data for 1994 and 1996. Microbial Drug Resistance 3, 263-266.

178. McLauchlin, J., Hampton, M.D., Shah, S., Threlfall, E.J., Wieneke, A.A. & Curtis, G.D.W. (1997) The subtyping of Listeria monocytogenes on the basis of plasmid profiles and arsenic and cadmium susceptibility. Journal of Applied Microbiology 83, 381-388.

179. Threlfall, E.J. & Ridley, A.M. (1997) Salmonella typhimurium DT 104. Microbiological Methods Innovation Forum 5, 8-10.

180. Threlfall, E.J., Ward, L.R. & Rowe, B. (1997) Increasing incidence of resistance to trimethoprim and ciprofloxacin in epidemic Salmonella typhimurium DT 104 in England and Wales. Eurosurveillance 2, 81-84.

181. Threlfall, E.J., Ward, L.R., Rowe, B. (1997) Incidence croissante de la résistance au



triméthoprime et à la ciprofloxacine de Salmonella typhimurium DT 104 épidémique en Angleterre et au Pays des Galles. Bulletin Épidémiologique Hebdomadaire No. 47/1997, 209-210.

182. Threlfall, E.J., Graham, A., Cheasty, T., Ward, L.R. & Rowe, B. (1997) Resistance to ciprofloxacinin pathogenic Enterobacteriaceae in England and Wales in 1996. Journal of Clinical Pathology 50, 1027-1028.

183. Ward, L.R. & Threlfall, E.J. (1997) Human salmonellosis in England and Wales - Current situation. In: Salmonella and Salmonellosis: Proceedings. Editors: Colin, P., Le Goux, J.M., Clement, G . Zoopole Develôpmént, Ploufragan, France; 1997. pp 547-549.

184. Wall, P.G., Ross, D., Van Someren, P., Ward, L.R., Threlfall, E.J. & Rowe, B. (1997) Features of the epidemiology of multidrug resistant Salmonella typhimurium in England and Wales. In: Salmonellaand Salmonellosis: Proceedings. Editors: Colin, P., Le Goux, J.M., Clement, G.. Zoopole Develôppmént, Ploufragan, France; 1997. pp 566-568.

185. Old, D.C. & Threlfall, E.J. (1998) Salmonella. In: Topley and Wilson's Microbiology and Microbial Infections, 9th Edition. Volume 2, Chapter 41. Systematic Bacteriology. Editors, Duerden, B.I., Balows,A. Publishers, Edward Arnold (London), 1998. pp 969-997.

186. Murdoch, D.A., Banatvala, N., Bone, A., Shoismatulloev, B.I., Ward, L.R. & Threlfall, E.J. (1998) B. Epidemic ciprofloxacin-resistant Salmonella typhi in Tajikistan. Lancet 351, 339.

187. Punia, P., Hampton, M.D., Ridley, A.M., Ward, L.R., Rowe, B. & Threlfall, E.J. (1998) Pulsed-field electrophoretic fingerprinting of Salmonella indiana and its epidemiological applicability. Journal of Applied Microbiology, 84, 103-107.

188. Threlfall, E.J., Angulo, F. & Wall, P.G. (1998) Ciprofloxacin-resistant Salmonella typhimurium DT 104. Veterinary Record 142, 255.

189. Cheasty, T., Skinner, J.A., Rowe, B. & Threlfall, E.J. (1998) Increasing incidence of antibiotic resistance in shigellas from humans in England and Wales. Microbial Drug Resistance 4, 57-60.

190. Humphrey, T.J., Threlfall, E.J., Cruickshank, J.G. (1998) Salmonellosis. In: Zoonoses. Editors, Palmer, S., Soulsby, Simpson, D. Oxford University Press, 1998. pp 191-206.

191. Rushdy, A.A., Stuart, J.M., Ward, L.R., Bruce, J., Threlfall, E.J., Punia, P. & Bailey, J. (1988) National outbreak of Salmonella senftenberg associated with infant food. Epidemiology and Infection 120, 125-128.

192. Threlfall, E.J. (1998) Development and application of molecular typing methods for bacterial food-borne pathogens. In: European Commission - BCR Information. Workshop on Microbiological Monitoring in the Water and Food Industry. Eds: Vicente da Cruz, I.M., Maier, E. Publ: EU Directorate- General Science, Research and Development. Report EUR 18257 EN, 1998. pp 11-15.

193. Threlfall, E.J., Hampton, M.D. & Ridley, A.M. (1998) Application of molecular methods to the study of infections caused by Salmonella spp. In: Woodford, N., Johnson, A.P. (editors). Molecular bacteriology: Protocols and clinical applications. Humana Press, Totowa, N.J., U.S.A. 1998. pp 355-368.

194. Threlfall, E.J., Cheasty, T., Graham, A. & Rowe, B. (1988) Antibiotic resistance in Escherichia coli isolated from blood and cerebrospinal fluid: a 6-year study of isolates from patients in England and Wales. International Journal of Antimicrobial Agents 9, 201-205.

195. Hampton, M.D., Ward, L.R., Rowe, B. & Threlfall, E.J. (1998) Molecular fingerprinting of Salmonella enterica serotype Typhi. Emerging Infectious Diseases 4, 317-320.

196. Frost, J.A., Thwaites, R. & Threlfall, E.J. (1998) Ciprofloxacin-resistant campylobacter. Journal of Clinical Pathology 51, 487

197. Threlfall, E.J. & Ridley, A.M. (1998) Application of molecular methods to Salmonella epidemiology. In: Aspán, A., Mulder, R.A.W. (editors). COST Action 97; 4. Development of monitoring procedures, rapid detection methods and techniques. Molecular epidemiology of campylobacter and salmonella. European Commission, EUR 18209 EN, 1998. pp 45-51.

198. Threlfall, E.J., Ward, L.R. & Rowe, B. (1998) Multiresistant Salmonella typhimurium DT 104 and salmonella bacteraemia. Lancet 352, 287-288.

199. Threlfall, E.J., Skinner, J.A. & McLauchlin, J. (1998) Antimicrobial resistance in Listeria monocytogenes from humans and food in the UK, 1967 - 96. Clinical Microbiology and Infection 4, 410-412.

200. Ridley, A.M., Threlfall, E.J. & Rowe, B. (1998) Genotypic characterisation of Salmonella enteritidis phage types by plasmid profile, ribotyping and pulsed-field gel electrophoresis. Journal of Clinical Microbiology 36, 2314-2321.

201. Ridley, A.M. & Threlfall, E.J. (1998) Molecular epidemiology of antibiotic resistance genes in



multiresistant epidemic Salmonella typhimurium DT 104. Microbial Drug Resistance 4, 113-118.

202. Threlfall, E.J., Ward, L.R., Hampton, M.D., Ridley, A.M., Rowe, B., Roberts, D., Gilbert, R.J., van Someren, P., Wall, P.G. & Grimont, P. (1998) Molecular fingerprinting defines a strain of Salmonella enterica serotype Anatum responsible for an international outbreak associated with formula-dried milk.Epidemiology and Infection, 121, 289-293.

203. Threlfall, E.J. (1998) Multiple antibiotic resistance in salmonellae. In: XXVIII Turk Mikrobiyoloji Cemiyeti, Klinik Mikrobiyoloji Infeksion Hastalikari Dernegi. Cati Grafik Reklamcilik Ltd, Istanbul. 1988, pp 26-27.

204. Threlfall, E.J. (1998) Development and application of molecular typing methods for Salmonella spp - the UK experience. Medical Journal of Indonesia 7 (suppl 1), 151-154.

205. Threlfall, E.J., Ward, L.R., Ridley, A.M. & Rowe, B. (1998) Resistance to fluoroquinolone antibiotics in humans in England and Wales - the current situation. In: Use of quinolones in food animals and potential impact on human health. Report and proceedings of a WHO meeting. World Health Organisation, 1998. pp 199-202.

206. Threlfall, E.J., Frost, J.A. & Rowe, B. (1999) Fluoroquinolone resistance in salmonellas and campylobacters from humans. British Medical Journal 318, 943-944.

207. Threlfall, E.J., Ward, L.R. & Rowe, B. (1999) Resistance to ciprofloxacin in non-typhoidal salmonellas from humans in England and Wales - the current situation. Clinical Microbiology and Infection 5, 130-134.

208. Threlfall, E.J., Ward, L.R., Skinner, J.A., Smith, H.R. & Lacey, S. (1999) Ciprofloxacin-resistant Salmonella typhi and treatment failure. Lancet 353, 1590-1991.

209. Cheasty, T., Said, B. & Threlfall, E.J. (1999) Vibrio cholerae non-O1 and food animals: implications for humans. Lancet 354, 88-89

210. Threlfall, E.J., Hampton, M.D., Ward, L.R., Richardson, I.R., Lanser, S. & Greener, T. (1999) Pulsed-field gel electrophoresis identifies an outbreak of Salmonella enterica serotype Montevideo infection associated with a supermarket hot food outlet. Communicable Disease and Public Health 2, 207-209

211. Threlfall, E.J., Ward, L.R. & Old, D.C. (1999) Changing the nomenclature of salmonella. Communicable Disease and Public Health 2, 156-157.

212. Threlfall, E.J. (1999) Advisory Committee’s report on microbial antibiotic resistance and food safety in the United Kingdom. Eurosurveillance Weekly, Issue 35, 3-4.

213. Guyot, A., Barrrett, S.P., Threlfall, E.J., Hampton, M.D. & Cheasty, T. (1999) Molecular epidemiology of multiresistant Escherichia coli. Journal of Hospital Infection 43, 39-48.

214. Threlfall, E.J., Fisher, I.S.T., Ward, L.R., Tschäpe, H. & Gerner-Smidt, P. (1999) Harmonisation of antibiotic susceptibility testing for Salmonella - results of a study by 18 national reference laboratories within the European Union-funded Enter-net group. Microbial Drug Resistance 5, 195-200.

215. Threlfall EJ, Ward LR, Frost JA, Cheasty T & Willshaw GA. (1999) The emergence and spread ofantibiotic resistance in food-borne bacteria in the United Kingdom. AUPA Newsletter 17, 1-7.

216. Threlfall, E.J. (2000) Microbial drug resistance – Implications for public health. In: Proceedings of ILSI Europe 2000 General Assembly Workshop on Resistant Microbes. pp 16-18.

217. Lucey, B., Crowley, D., Moloney, P., Cryan, B., Daly, M., Threlfall, E.J. & Fanning, S. (2000) Integronlike structures in Campylobacter spp. of human and animal origin. Emerging Infectious Diseases 6, 50-55.

218. Livermore, D.M., Threlfall, E.J., Reacher, M.H., Johnson, A.P., James, D., Cheasty, T., Shah, A., Warburton, F., Skinner, J., Graham, A. & Speller, D.C.E. (2000) Are routine sensitivity test data suitable for the surveillance of resistance? Resistance rates amongst Escherichia coli from blood and CSF from 1991-97 as assessed by routine and centralised testing. Journal of Antimicrobial Chemotherapy 45, 205-211.

219. Threlfall, E.J. (2000) Update on Salmonella typhimurium DT 104. In: Symposium series on trends and perspectives in microbial food safety. ILSI North America Technical Committee on Food Microbiology, 1998. pp 22.

220. Ward, L.R., Threlfall, E.J., O’Brien, S.J. & Smith, H.R. (2000) Salmonella enteritidis epidemic. Science 287, 17-18.

221. Ripabelli, G., McLauchlin, J., Mithani, V. & Threlfall, E.J. (2000) Epidemiological typing of Bacillus cereus by amplified fragment length polymorphism (AFLP). Letters in Applied Microbiology 30, 358-363.

222. Threlfall, E.J., Ward, L.R., Frost, J.A. & Willshaw, G.A. (2000) Spread of resistance from food



animals to man – the UK experience. In : In: Proceedings of the symposium on antibiotic resistance with emphasis on animal-human transfer. Acta Veterinaria Scandanavia, Supplement 93, 63-69.

223. Ripabelli, G., McLauchlin, J. & Threlfall, E.J. (2000) Amplified fragment length polymorphism (AFLP) analysis of Listeria monocytogenes . Systemic and Applied Microbiology 23, 132-136

224. Maguire, H., Pharoah, P., Walsh, B., Davison, C., Barrie, D., Threlfall, E.J. & Chambers, S. (2000)Hospital outbreak of Salmonella virchow possibly associated with a food handler. Journal of Hospital Infection 4, 261-266.

225. McLauchlin, J., Ripabelli, G., Bret MM & Threlfall, E.J. (2000) Amplified fragment length polymorphism (AFLP) analysis of Clostridium perfringens for epidemiological typing. International Journal of Food Microbiology 56, 21-28.

226. Threlfall, E.J. (2000) Epidemic Salmonella typhimurium DT 104 – a truly international epidemic clone. Journal of Antimicrobial Chemotherapy (Leading Article) 46, 7-10.

227. Walker, R.A., Lawson, A.J., Lindsay, E.A., Ward, L.R., Wright, P.A., Bolton, F.J., Wareing, D.R., Corkish, J.D., Davies, R.H., & Threlfall E.J. (2000) Decreased susceptibility to ciprofloxacin in outbreak-associated multiresistant Salmonella Typhimurium DT104. Veterinary Record 147, 395-396.

228. Threlfall, E.J. (2000) Salmonella enterica (Book review). Veterinary Record 147, 168.

229. Kariuki, S., Oundo, J.O., Muyodi, J., Threlfall, E.J. & Hart, C.A. (2000) Genotypes of multidrug-resistant Salmonella enterica serotype Typhimurium from two regions of Kenya. FEMS Microbiology Letters 29, 9-13.

230. Martin, G.M., Chart, H., Threlfall, E.J., Morgan, E., Lodge, J.M., Brown, N.L. & Stephen, J. (2000)Invasiveness of Salmonella serotypes Typhimurium and Enteritidis of human gastro-enteric origin for rabbit ileum: role of LPS, plasmids, and host factors. Journal of Medical Microbiology 99, 1101-1021.

231. Threlfall, E.J., Skinner, J.A., Graham, A., Ward, L.R. & Smith, H.R. (2000) Resistance to ceftriaxone and cefotaxime in non-typhoidal Salmonella enterica in England and Wales. Journal of Antimicrobial Chemotherapy 46, 860-862.

232. Threlfall, E.J., Ward, L.R., Frost, J.A., & Willshaw, G.A. (2000) The emergence and spread of antibiotic resistance in food-borne bacteria. International Journal of Food Microbiology 62, 1-5.

233. Threlfall, E.J. (2000) Harmonisation of antibiotic susceptibility testing for salmonellas. In: In: Colin,P., Mulder, R.W.A.W Mulder. (editors). COST Action 97; 10. Development of monitoring procedures, rapid detection methods and techniques. European Communities 2000. pp 44-46..

234. Threlfall, E.J., Ward, L.R., Skinner, J.A. & Graham, A. (2000) Antimicrobial drug resistance in non-typhoidal salmonellas from humans in England and Wales in 1999: Decrease in multiple resistance in Salmonella enterica serotypes Typhimurium, Virchow and Hadar. Microbial Drug Resistance 6, 319-325.

235. Fisher IST, Mather H, Briem H, Hardardottir H, Ward LR, Threlfall EJ et al. (2000) Outbreaks of S.typhimurium DT204b infections in England and Wales, Scotland and elsewhere in Europe. Eurosurveillance Weekly 4: 000928.

236. Desai, M., Threlfall, E.J. & Stanley, J. (2001) Fluorescent amplified-fragment length polymorphism subtyping of the Salmonella enterica serovar Enteritidis phage type 4 clone complex. Journal of Clinical Microbiology 39, 201-206.

237. Walker, R.A., Saunders, N., Lawson, A.J., Lindsay, E.A., Dassama, M., Ward, L.R., Woodward, M.J., Davies, R.H. & Threlfall, E.J. (2001) Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates. Journal of Clinical Microbiology 39, 1443-1448.

238. Threlfall, E.J. (2001) Microbial drug resistance: implications for human health. Mitteilungen aus Lebensmitteluntersuchung und Hygiene 92, 59-67.

239. Walker, R., Lindsay, E., Woodward, M.J., Ward, L.R. & Threlfall, E.J (2001) Variation in antibiotic resistance genes amongst multiresistant Salmonella enterica serotype Typhimurium phage type U302(MR U302) from humans, animals and foods. Microbial Drug Resistance 7, 13-21

240. Threlfall, E.J. & Ward, L.R. (2001) Decreased susceptibility to ciprofloxacin in Salmonella entericaserotype Typhi in the United Kingdom. Emerging Infectious Diseases 7, 448-450.

241. Threlfall, E.J., Lawson, A.J., Walker, R.A. & Ward, L.R. (2001) Salmonella typhimurium DT 104: the rise and fall of a multiresistant epizootic clone. SCIEH Weekly Report 35, 142-144.

242. Threlfall, E.J. & Peters, T. (2001) Commentary – Molecular epidemiologic analysis of Salmonella enterica serotype Derby infections in Hong Kong. Journal of Infection 42, 85-86.

243. Threlfall, E. J., Ward, L.R. (2001) Enteric fever treatment failures: a global concern. (Reply to Drs



Chandel & Chaudhrey) Emerging Infectious Diseases 7, 763-764.

244. Vose, D., Acar, J., Anthony, F., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2001) Antimicrobial resistance: risk analysis methodology for the potential impact on public health of antimicrobial resistantbacteria of animal origin. OIE Scientific and Technical Review 20, 23-36.

245. Anthony, F., Acar, J., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2001) Antimicrobial resistance: responsible and prudent use of antimicrobial agents in veterinary medicine. OIE Scientific and Technical Review 20, 52-69.

246. Nicholls, T., Acar, J., Anthony, F., Franklin, A., Gupta, R., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2001) Antimicrobial resistance: monitoring the quantities of antimicrobials used in animal husbandry. OIE Scientific and Technical Review 20, 70-78.

247. White, D.G., Acar, J., Anthony, F., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., Wegenar, H. & Costaricca, L. (2001) Antimicrobial resistance:standardisation and harmonisation of laboratory methodologies for the detection and quantification of resistance. OIE Scientific and Technical Review 20, 79-88.

248. Franklin, A., Acar, J., Anthony, F., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., Wegenar, H. White, D.G. & Costaricca, L. (2001) Antimicrobial resistance: harmonisation of national antimicrobial resistance monitoring and surveillance programmes in animals and animal-derived food. OIE Scientific and Technical Review 20, 93-104.

249. Scott, F., Threlfall, E.J., Stanley, J. & Arnold, C. (2001) Fluorescent Amplified Fragment Length Polymorphism genotyping typing of Salmonella Enteritidis: a method suitable for rapid outbreak recognition. Clinical Microbiology and Infection 7, 479-485.

250. Threlfall, E.J., Skinner, J.A. & Ward, L.R. (2001) Detection of decreased in vitro susceptibility to ciprofloxacin in Salmonella enterica serotypes Typhi and Paratyphi A. Journal of Antimicrobial Chemotherapy 48, 740-741.

251. Threlfall, E.J. (2001) Implications for human health. In: Resistant microbes: where are we and where do we go? Report of the ILSI Europe 2000 General Assembly Workshop, Limelette, Belgium. pp 11-16.

252. Threlfall, E.J. (2001) Strengthening international salmonella surveillance through strain typing anddifferentiation. In: Dr Anne Lőnroth (editor), Antimicrobial resistance research in the Quality of life and management of living resources programme. European Commission, Directorate-General for Research 2001. Brussels. pp 26-27.

253. Ward, L.R. & Threlfall, E.J (2001) The emergence of a new Salmonella Typhimurium phage type associated with pigs. In: Peter J. van der Wolf (editor), Proceedings of the 4th International Symposium on the epidemiology and Control of Salmonella and other Food Borne Pathogens in Pork.Salinpork 2001. Labor Diagnoskik GmbH Leipzig. pp 174-176.

254. Peters, T.M. & Threlfall, E.J. (2001) Single-enzyme amplified fragment length polymorphism and its applicability for Salmonella epidemiology. Systematic and Applied Microbiology 24, 400-404.

255. Threlfall, E.J. (2002) Resistant gut bacteria. In: Manson's Tropical Diseases, 21st edition. Editors, Cook, G.C., Zulma, A. Saunders, London. pp 951-962.

256. Sood, S., Peters, T., Ward, L.R. & Threlfall, E.J. (2002) Single enzyme amplified fragment length polymorphism (SAFLP) for determination of strain relationships in multiple drug-resistant Salmonella enterica serotype Typhimurium. Clinical Microbiology and Infection 8, 154-161.

257. Lawson, A.J., Dessama, M.U., Ward, L.R. & Threlfall, E.J. (2002) Multiple resistant Salmonella enterica serovar Typhimurium DT 12 and 120: a case of MR DT 104 in disguise? Emerging Infectious Disease 8, 434-436.

258. Lawson, A.J., Chart, H., Dessama, M.U. & Threlfall, E.J. (2002) Heterogeneity in expression of lipopolysaccharide by strains of Salmonella enterica serotype Typhimurium definitive type 104 and related phage types. Letters in Applied Microbiology 34, 428-430.

259. Scott, F., Threlfall, E J. &, Arnold, C. (2002) Genetic structure of Salmonella revealed by fragmentanalysis International Journal of Systematic and Evolutionary Microbiology 52, 1701-1703.

260. Liebana, E., Clouting, C., Cassar, C., Randall, L.P., Walker, R.A., Threlfall, E.J., Clifton-Hadley, F.A., Ridley, A.M. & Davies, R.H. (2002) Comparison of gyrA mutation, cyclohexane resistance and presence of class 1 integrons in Salmonella enterica from farm animals. Journal of Clinical Microbiology 40, 1481-1486.

261. Lindsay, E.A., Lawson, A. J., Walker, R.A., Ward, L.R., Smith, H.R., Scott, F.W., Fisher, I.S.T.,



Crook, P., Wilson, D., Brown, D.J., Hardardottir, H., Van Pelt, Wilfred, Tschäpe, H. & Threlfall, E.J. (2002) Role of electronic data exchange in an international outbreak caused by Salmonella enterica serotype Typhimurium DT204b. Emerging Infectious Diseases 8, 732-734.

262. Threlfall, E.J. (2002) Antimicrobial drug resistance in Salmonella: problems and perspectives in food and water-borne infections. FEMS Microbiology Reviews 26, 141-148.

263. Threlfall, E.J., Skinner, J.A, Graham, A. & Ward, L.R. (2002) Antimicrobial drug resistance in non-typhoidal salmonellas from humans in England and Wales, 2000: dramatic increase in multiple resistance in Salmonella enterica serotypes Typhimurium and Virchow. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 445-450.

264. Lindsay, E.A., Lawson, A.J., Walker, R.A.,.Ward, L.R., Smith, H.R., Scott, F.W., O’Brien, S.J., Fisher, I.S.T., Crook, P.D., Wilson, D., Brown, D.J., Hardardottir, H., Wannet, W.J.B., Tschäpe, H. & Threlfall, E.J. (2002) Molecular characterisation of a multiresistant strain of Salmonella enterica serotype Typhimurium DT204b responsible for an international outbreak of salmonellosis: importance of electronic exchange of gel data for outbreak investigations. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 43-47.

265. Ward, L.R., Maguire, C., de Pinna, E., Smith, H.R., Threlfall, E.J., Gillespie, I., O'Brien, S.J., Little,C., Mitchell, R.T., Sharp, C., Swann, A. & Doyle, O. (2002) A collaborative investigation of an outbreak of Salmonella enterica serotype Newport in England and Wales in 2001 associated with ready-to-eat salad products: the importance of the combination of microbiology and epidemiology in disease control. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin,P., Clement, G. Zoopole - ISPAIA, 2002. pp 433-434.

266. Hampton, M.D. & Threlfall, E.J. (2002) The use of the Multi Variate Statistical Package (MVSP) and bionumerics for analysis and interpretation of XbaI-restricted pulsed-field profiles of Salmonella enterica serovars. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 81-83.

267. Ward, L.R., Threlfall, E.J. & O’Brien, S.J. (2002) The changing trends of salmonellosis in Englandand Wales. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 393-396.

268. Scott, F.W., Threlfall, E.J. & Arnold, C. (2002) Genetic Structure of Salmonella Subspecies. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 27-35.

269. Liebana, E., Garcia-Migura, L., Clouting, C., Cassar, C.A., Clifton-Hadley, F.A., Lindsay, E.A., Threlfall, E.J &, Davies, R.H. (2002) A comparative analysis of the genetic diversity among isolates of Salmonella enterica serovar Dublin from animals and humans in the United Kingdom. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 89-90.

270. Peters, T., Threlfall, E.J., Cheasty, T. & Willshaw, G.A. (2002) DNA sequenced based approachesas an alternative for serotyping Salmonella enterica and Escherichia coli. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 93-94.

271. Leuschner, R.G.K., Montague, S.R., Threlfall, E.J. & McDonald, B.C. (2002) Comparison of amplified restriction fragment polymorphism (AFLP) using conventional and capillary electrophoresis for Salmonella typing. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 101-102.

272. Crook, P.D., Aguilera, J.-F., O'Brien, S.J., Threlfall, E.J., Sigmundsdóttir, G., Wilson, D., Fisher, I.S.T., Ammon, A., Briem, A., Cowden, J.M., Locking, M.E., Tschape, H., Van Pelt, W., Ward, L.R. & Widdowson, M.A. (2002) The epidemiological investigation of a major European outbreak of Salmonella enterica serotype Typhimurium definitive phage type 204b. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2002. pp 387-391.

273. Goodyear, K., Teale, C. & Threlfall, E.J.(2002) Veterinary surveillance for antimicrobial resistance.Journal of Antimicrobial Chemotherapy 50, 612-614.

274. Liebana E, Garcia-Migura, L., Clouting, C., Cassar, C., Clifton-Hadley, F.A., Lindsay, E.A., Threlfall, E.J., & Davies, R.H. (2002) Investigation of the genetic diversity among isolates of Salmonella enterica serovar Dublin from animals and humans in England, Wales and Ireland. Journal of Applied Microbiology 93, 732-44.

275. Ward, L.R,, Maguire, C., Hampton, M.D., de Pinna, E., Smith, H.R., Gillespie, I.A., O'Brien, S.J., Little, C.L., Mitchell, R.T., Sharp, C., Swann, R.A., Doyle, O. & Threlfall, E.J., (2002) A collaborative



investigation of an outbreak of Salmonella enterica serotype Newport in England and Wales in 2001 associated with ready-to-eat salad vegetables: the combination of microbiology and epidemiology in disease investigations. Communicable Disease and Public Health 5, 301-304.

276. Liebana, E., Garcia-Migura, L., Clouting, C., Clifton-Hadley, F.A., Lindsay, E., Threlfall, E.J., McDowell, S.W. & Davies, R.H. (2002) Multiple genetic typing of Salmonella enterica serotype Typhimurium isolates of different phage types (DT104, U302, DT204b, and DT49) from animals and humans in England, Wales and Northern Ireland. Journal of Clinical Microbiology 40, 4450-4456.

277. Aarestrup, F.M., Wiuff, C., Mølbak, K. &, Threlfall, E.J. (2003) Is it time to change the break pointsfor fluoroquinolones for Salmonella spp.? Antimicrobial Agents and Chemotherapy 47, 827-829

278. Threlfall E.J., Fisher, I.S.T., Berghold, C., Gerner-Smidt, P., Tschäpe, H., Cormican, M., Luzzi, I., Schnieder, F., Wannet, W., Machado, J. & Edwards, G. (2003) Antimicrobial drug resistance in Salmonella enterica in Europe in 2000: results of international multi-centre surveillance. Eurosurveillance 8, 41-45.

279. Peters, T.M., Maguire, C., Threlfall, E.J., Fisher, I.S.T. & Gill, N. (2003) DNA fingerprinting for international surveillance of food-related salmonellosis – a European collaboration. Eurosurveillance 8,46-50.

280. Horby, P.W., O'Brien, S.J., Adak, G.K., Graham, C., Hawker, J.I., Hunter, P., Lane, C., Lawson, A.J., Mitchell, R.T., Reacher, M.H., Threlfall, E.J. & Ward, L.R. (2003) A national outbreak of multi-resistant Salmonella enterica serovar Typhimurium definitive phage type (DT) 104 associated with consumption of lettuce. Epidemiology & Infection 130, 169-178.

281. Threlfall, E.J., Teale, C.J., Ward, L.R., Davies, R.H., Skinner, J.A., Graham, A., Cassar, C. & Speed, K. (2003) A comparison of antimicrobial susceptibilities in non-typhoidal salmonellas from humans and food animals in England and Wales. Microbial Drug Resistance 9, 183-189.

282. Crook, P.D., Aguilera, J.-F., Threlfall, E.J., O'Brien, S.J., Sigmundsdóttir, G., Wilson, D., Fisher, I.S.T., Ammon, A., Briem, H., Cowden, J.M., Locking, M.E., Tschäpe, H. van Pelt, W., Ward, L.R. & Widdowson, M.A. (2003) A European outbreak of Salmonella enterica serotype Typhimurium Definitive Phage Type 204b in 2000. Clinical Microbiology and Infection 9, 839-845.

283. Threlfall, E.J. (2003) Resistant Gut Bacteria. In: Manson's Tropical Diseases, 21st Edition. Editors, Cook, G.C., Zumla, A.I. Publishers, W.B Saunders. London. pp 951-962.

284. Threlfall, E.J. (2003) Antimicrobial drug resistance from salmonellas in humans and food animals;the current situation in relation to foodborne zoonoses in the United Kingdom. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World organisation for animal health), Paris, 2003. pp 69-70.

285. White, D.G., Acar, J., Anthony, F., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., Wegenar, H. & Costaricca, L. (2003) Antimicrobial resistance:standardisation and harmonisation of laboratory methodologies for the detection and quantification of resistance. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World organisation for animal health), Paris, 2003. pp 223-238.

286. Nicholls, T., Acar, J., Anthony, F., Franklin, A., Gupta, R., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2003) Antimicrobial resistance: monitoring the quantities of antimicrobials used in animal husbandry. In: OIE Standards onAntimicrobial Resistance. Publishers: OIE (World organisation for animal health), Paris, 2003. pp 109-117.

287. Threlfall E.J., Fisher, I.S.T., Berghold, C., Gerner-Smidt, P., Tschäpe, H., Cormican, M., Luzzi, I., Schnieder, F., Wannet, W., Machado, J. & Edwards, G. (2003) Trends in antimicrobial drug resistance in Salmonella enterica serotypes Typhi and Paratyphi A isolated in Europe, 1999-2001. International Journal of Antimicrobial Agents 22, 487-491.

288. Vose, D., Acar, J., Anthony, F., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2003) Antimicrobial resistance: risk analysis methodology for the potential impact on public health of antimicrobial resistantbacteria of animal origin. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World Organisation for Animal Health), Paris, 2003. pp 113-161.

289. Anthony, F., Acar, J., Franklin, A., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., White, D.G., Wegenar, H. & Costaricca, L. (2003) Antimicrobial resistance: responsible and prudent use of antimicrobial agents in veterinary medicine. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World Organisation for Animal Health), Paris, 2003. pp 249-266

290. Franklin, A., Acar, J., Anthony, F., Gupta, R., Nicholls, T., Tamura, Y., Thompson, S., Threlfall, E.J., Vose, D., van Vuuren, M., Wegenar, H. White, D.G. & Costaricca, L. (2003) Antimicrobial resistance: harmonisation of national antimicrobial resistance monitoring and surveillance



programmes in animals and animal-derived food. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World Organisation for Animal Health), Paris, 2003. pp 181-199.

291. Fisher, I.S.T., Gill, O.N., Reilly, W.J., Smith, H.R. & Threlfall, E.J (2003). Harmonisation of antimicrobial resistance testing results – the outcome of the international Enter-net study. In: OIE Standards on Antimicrobial Resistance. Publishers: OIE (World organisation for animal health), Paris, 2003. pp 245-248.

292. Walker, R.A., Skinner, J.A., Ward, L.R. & Threlfall, E.J. (2003) Lightcycler gyrA mutation assay (GAMA) identifies heterogeneity in GyrA in Salmonella enterica serotypes Typhi and Paratyphi A with decreased susceptibility to ciprofloxacin. International Journal of Antimicrobial Agents 22, 622-625.

293. Ward, L.R., De Pinna, E., & Threlfall, E.J. (2003) Salmonella typhimurium phage types linked withpigs and their association with human infection in England and Wales. In: Proceedings of 5th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork. Editor: Leonidas, L. Publisher: School of Veterinary Medicine, University of Thessaly, Greece. 2003. pp 196-198.

294. Threlfall, E.J., Hampton, M.D., Chart, H., Hopkins, K., Ward, L.R. & Tebbutt, G. (2004) Emergence of new subclones of multiresistant S typhimurium DT104 possibly associated with poultry. Veterinary Record 154, 89-90.

295. Lawson, A. J., Desai, M., O'Brien, S.J., Davies, R.H., Ward, L.R. & Threlfall, E.J. (2004) Molecular characterization of an outbreak strain of multiresistant Salmonella enterica serovar Typhimurium DT104 in the United Kingdom. Clinical Microbiology and Infection 10, 143-147.

296. Hopkins, K.L. & Threlfall, E.J. (2004) Frequency and polymorphism of the SopE gene in isolates of Salmonella enterica belonging to the ten most prevalent serotypes in England and Wales. Journal of Medical Microbiology 53, 539-43.

297. Threlfall, E..J., Ward, L.R., Fisher, I.S.T. (2004) New multiresistant strain of Salmonella enterica serotype Choleraesuis detected in Taiwan. – editorial comment. Euro Surveillance Weekly 8 (17) 22/04/2004.

298. Liebana, E., Clouting, C., Garcia-Migura, L., Clifton-Hadley, F.A., Lindsay, E., Threlfall, E.J. & Davies, R.H. (2004) Multiple genetic typing of Salmonella Enteritidis phage-types 4, 6, 7, 8 and 13a isolates from animals and humans in the UK. Veterinary Microbiology 100, 189-195.

299. O’Brien, S., Gillespie, I., Charlett, A., Adak, B., Threlfall, E.J., Ward, L.R. (2004). National case-contol study of Salmonella Enteritidis phage type 14B infections in England and Wales implicates eggs used in the catering trade. Eurosurveillance 9, 50.

300. Kirk, M.D., Little, C.L., Lem, M., Fyfe, M., Tan, A., Threlfall, E.J., Paccagnella, A., Lightfoot, D., Genobile, D., Ward, L.R., Brown, D.J., Surman, S. & Fisher, I.S.T. (2004) An outbreak due to peanuts in their shell caused by Salmonella serotypes Stanley and Newport - sharing molecular information to solve international outbreaks. Epidemiology & Infection 132, 571-577.

301. .Threlfall E.J. (2004) Fluoroquinolone-resistant Campylobacter infections and animal drug use (response to correspondence). International Journal of Infectious Diseases 8, 190-192.

302. Threlfall, E.J. (2004). Surveillance tools supporting an integrated approach to traceability through the food chain. In: Beyond thinking tomorrow: a safe and nutritious food chain for the consumer. Teagasc, 2004. pp 55-62.

303. Goodyear, K., Threlfall, E.J. (2004) Use of veterinary antimycotic products in the UK, 1998-2002. International Journal of Antimicrobial Agents 24, 311-314.

304. White D.G., Acar, J., Anthony, F., Franklin, A., Roestel, B. & Threlfall, E.J. (2004) Laboratory methods for bacterial antimicrobial susceptibility testing. OIE Terrestrial Animal Health Code, OIE Publications, 2004

305. Cheasty, T., Day, M. & Threlfall, E.J. (2004) Increasing incidence of resistance to nalidixic acid in shigellas from humans in England and Wales: implications for therapy. Clinical Microbiology and Infection 10, 1033-1035

306. Defra Antimicrobial Resistance Co-ordination Group (membership – Fitzgerald, J., Goodyear, K., Kay, J., Davies, P., Threlfall, E.J., Teale, C., et al.) (2004) Strategy for developing and implementing a programme of surveillance for antimicrobial resistance in animals in England and Wales. Defra Publications, London. 2004

307. Working Group on Opinion of the Scientific Panel on Biological Hazards related to the use of antimicrobials for the control of Salmonella in poultry (Members: Colin, P., Davies, R.H., Greko, C., Klein, G., Kruse, H., Ricci, A., Threlfall, E.J.) (2004). EFSA Journal 115, 1-76.

308. Lawson, A.J., Stanley, J., Threlfall, E.J. & Desai, M. (2004) Fluorescent Amplified Fragment Length Polymorphism subtyping of multiresistant Salmonella enterica serovar Typhimurium DT104



(MR DT104). Journal of Clinical Microbiology 42, 4843-4845.

309. Liebana, E., Batchelor, M., Clifton-Hadley, F.A., Davies, R.H. & Threlfall, E.J. (2004) First report ofSalmonella isolates with the DHA-1 AmpC ß-lactamase in the United Kingdom. Antimicrobial Agents and Chemotherapy 48, 4492.

310. Threlfall, E.J., Fisher, I.S.T. (2004) Antibiotic resistance trends in Europe. Food Protection Trends 24, 750-751.

311. Threlfall, E.J., Levent, B., Hopkins, K.L., De Pinna, E., Ward, L.R. & Brown, D.J. (2005) Multidrug-resistant Salmonella Java. Emerging Infectious Diseases 1, 170-171.

312. Fisher, I.S.T., Threlfall E.J. (2005) The Enter-net and Salm-gene databases of food-borne bacterial pathogens causing human infections in Europe and beyond: an international collaboration in the development of intervention strategies. Epidemiology & Infection 133, 1-7

313. Teale, C.J., Barker, L., Foster, A., Liebana, E., Batchelor, M., Livermore, D. & Threlfall, E.J.(2005) Extended-spectrum beta-lactamase detected in E. coli from calves in Wales. Veterinary Record 156, 186-187.

314. Evans, S.J., Davies, R.H., Binns, S.H., Jones, T.W.H., Liebana, E., Millar, M.F., Threlfall, E.J., Ward, L.R., Hopkins, K.L., Mackay, P.H.S., Gayford, P.J.R., Bailie, H. (2005) Multiple antimicrobial resistant Salmonella Paratyphi B variant Java in cattle: A case report. Veterinary Record 166, 343-346.

315. Batchelor, M., Hopkins, K.A., Threlfall, E.J., Clifton-Hadley, F.A., Stallwood, A.D, Davies, R.H.& Liebana, E. (2005) bla CTX-M genes in clinical isolates of Salmonella recovered from humans in England and Wales from 1992 to 2003. Antimicrobial Agents & Chemotherapy 49, 1319-1322.

316. Goodyear, K.L. & Threlfall, E.J. (2005) Use of veterinary antiprotozoal products in the UK, 1998-2002. International Journal of Antimicrobial Agents, 25, 279-281.

317. Hopkins, K., Davies, R.H. & Threlfall, E.J. (2005) Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments: International Journal of Antimicrobial Agents 25, 358-373.

318.O’Brien, S.J., Ward, L.R., Adak, G.K., Gillespie, I.A., Little, C.L., Nichols, G., Smith, H.R., Surman,S. & Threlfall, E.J. (2005) Multiple, common source outbreaks of Salmonella Enteritidis in England andWales in 2002 and 2003 – possible association with imported raw shell eggs.

Clinical Microbiology and Infection, in press

319.Batchelor, M., Hopkins, K., Threlfall, E.J., Clifton Hadley, F.A., Stallwood, A.D., Davies, R.H. & Liebana, E. (2005) Characterisation of AmpC genes in clinical Salmonella isolates recovered from humans during the period 1992-2003 in England and Wales. Antimicrobial Agents & Chemotherapy 43, 2261-2265.

320.Threlfall, E.J. (2005) Salmonella. In: Topley and Wilson's Microbiology and Microbial Infections, 10th Edition, part VI. Editors: Borriello, SP, Murray PR, Funke G. Publishers: Hodder Arnold (London), 2005. pp 1398-1434.

321Threlfall, E.J., Hopkins, K.L.& Ward, L.R. (2005) Evolutionary diversification within Salmonella Typhimurium DT 104. Emerging Infectious Diseases 11, 980-981.

322.Carattoli, A., Bertini, A., Lilla, L., Falbo, V., Hopkins, K. & Threlfall EJ (2005) Identification of plasmids by PCR-based replicon typing. Journal of Microbiological Methods 63, 219-228.

323. Batchelor, M. Threlfall, E.J. & Liebana, E. (2005) Cephalosporin resistance among animal-associated Enterobacteria: A current perspective. Expert Review of Anti-infective Therapy 3, 403-417.

324.Threlfall, E.J. (2005) Drug resistance in Salmonella and Shigella. In: Frontiers in Antibiotic Resistance: A tribute to Stuart B. Levy. Eds, White, D.G., Alkeshun, M.N., McDermott, P. ASM Publications. Washington DC, 2005. pp 367-373.

325. McLauchlin, J., Threlfall, E.J. (2005) Surveillance of foodborne diseases by the Health Protection Agency. Parliamentary Monitor 134, 68-69

326. Liebana, E., Batchelor, M., Hopkins, K.L., Clifton-Hadley, F.A., Davies, R.H. & Threlfall, E.J. (2005) Resistance to oxyminocephalosporins mediated by blaTEM-52 genes in Salmonella Typhimurium from humans in England and Wales. Foodborne Pathogens and Disease 2, 361-364.

327.Gatto, A.J., Peters, T.M., Green, J., Fisher, I.S.T., Gill, O.N., O’Brien, S.J., Maguire, C., Berghold, C., Leder, I., Gerner-Smidt, P., Torpdahl, M., Siitonen, A., Lukinmaa, S., Tschape, H., Prager, R., Luzzi,I., Dionisi, A.M., Wannet, W., Heck, M., Coia, J., Brown, D., Usera, M., Echeita, A. & Threlfall, E.J. (2006) Distribution of molecular subtypes within Salmonella enterica serotype Enteritidis phage type 4 and S. Typhimurium definitive phage type 104 in nine European countries, 2000-2004: results of an international multi-centre study. Epidemiology and Infection 134, 729-736.



328.Threlfall, E.J., Day, M., De Pinna, E., Charlett, A & Goodyear, K. (2006) Assessment of factors contributing to changes in the incidence of antimicrobial drug resistance in Salmonella enterica serotypes Enteritidis and Typhimurium from humans in England and Wales in 2000, 2002 and 2004. International Journal of Antimicrobial Agents 5, 389-395.

329.Hopkins, K.L., Liebana, E., Villa, L., Batchelor, M., Threlfall, E.J. & Carattoli, A.(2006) Replicon typing of plasmids carrying CTX-M or CMY ß-lactamases circulating among Salmonella and Escherichia coli in the UK. Antimicrobial Agents and Chemotherapy 50, 3203-3206.

330.Hopkins, K.L., Deheer-Graham, A., Karisik, E., Batchelor, M.J., Liebana, E. & Threlfall, E.J. (2006). New plasmid-mediated AmpC beta-lactamase (CMY-21) in Escherichia coli isolated in the UK.International Journal of Antimicrobial Agents 28, 80-82

331.Hopkins, K.L., Deheer-Graham, A., Batchelor, M.J., Liebana, E & Threlfall, E.J. (2006) Novel plasmid-mediated CTX-M-8 subgroup extended spectrum beta-lactamase (CTX-M-40) isolated in the UK. International Journal of Antimicrobial Agents 27, 572-575.

332.Liebana, E., Batchelor, M., Hopkins, K.L., Clifton-Hadley, F.A., Teale, C.J., Foster, A., Barker, L., Threlfall, E.J. & Davies, R.H. (2006) Longitudinal farm study of extended-spectrum beta lactamase-mediated resistance. Journal of Clinical Microbiology 44, 1630-1644.

333. Threlfall, E.J., Day, M., de Pinna, E., Lewis, H. & Lawrence, J. (2006) Drug-resistant enteric fever in the UK. Lancet 367, 1576.

334.Liebana, E., Best, E.L., Lindstedt, B.-A., Clifton-Hadley, F.A., Threlfall, E.J. & Cook, A. (2006) Application of Variable-Number of Tandem-Repeats (VNTR) analysis to Salmonella Typhimurium: a longitudinal investigation on pig farms and assessment of its value for food attribution of human cases.In: I3S – International Symposium Salmonella and Salmonellosis. Editors, Colin, P., Clement, G. Zoopole developpment – ISPAIA, 2006. pp 109-110.

335.Liebana, E., Hopkins, K., Villa, L., Batchelor, M., Threlfall, E.J, & Carattoli, A. (2006) Replicon typing of plasmids carrying CTX-M or CMY -lactamases circulating among Salmonella and Escherichia coli in the United Kingdom. In: I3S – International Symposium Salmonella and Salmonellosis. Editors, Colin, P., Clement, G. Zoopole developpment – ISPAIA, 2006. pp 221-222.

336.Threlfall, E.J., Day, M. & Ward, L.R. (2006) Trends in antimicrobial resistance in Salmonella from humans isolated in England and Wales from 2000 to 2004. In: I3S – International Symposium Salmonella and Salmonellosis. Editors, Colin, P., Clement, G. Zoopole developpment – ISPAIA, 2006.pp 153-154.

337. Gillespie, I.A., Adak, G.A. & Threlfall, E.J. (2006) National outbreak of Salmonella Ajiobo infectionin England and Wales. Euro Surveillance Weekly 11, issue 7, 3-4.

338. Cooke, F.J., Threlfall, E.J. & Wain, J.(2006). New mechanism of fluoroquinolone resistance in Salmonella Typhi? British Medical Journal - rapid responses. http://bmj.bmjjournals.com/cgi/eletters/333/7561/260-b. 2nd August 2006

339. Cooke, F.J., Threlfall, E.J. & Wain, J. (2006). Fluoroquinolone resistance in Salmonella Typhi. British Medical Journal 333, 353-354.

340. Hopkins, K.L., Batchelor, M.J., Liebana, E., Deheer-Graham, A. & Threlfall, E.J. (2006) Characterisation of CTX-M and AmpC genes in human isolates of Escherichia coli identified between 1995 and 2003 in England and Wales. International Journal of Antimicrobial Agents 28, 180-192

341 Threlfall, E.J. (2006) Professor E. S. Anderson FRS, CBE – an obituary. Bulletin of the Royal College of Pathologists, 136, 55-57.

342. Cooke, F.J., Threlfall, E.J., Wain, J. (2006) Current trends in the spread and occurrence of humansalmonellosis: Molecular typing and emerging antibiotic resistance. In: Editors, Rein, M., Maskell, D.J.,Threlfall, E.J. Salmonella: Molecular Biology and Pathogenesis. Horizon Bioscience 2006, pp 1 - 29.

343.Rein, M., Maskell, D.J., Mastroeni, P., Threlfall, E.J (Editors). Salmonella: Molecular Biology and Pathogenesis. Horizon Bioscience . 2006.

344. Little, C.L., Walsh, S., Hucklesby, L., Surman-Lee, S., Pathak, K., de Pinna, E., Threlfall, E.J., Maund, A., Chan C.-H. (2006) Food Standards Agency survey of Salmonella contamination of non-UK produced shell eggs on retail sale in the north-west of England and London. Euro Surveillance, http://www.eurosurveillance.org/ew/2006/061123.asp#4

345. Little, C.L., Walsh, S., Hucklesby, L., Surman-Lee, S., Pathak, K., de Pinna, E., Threlfall, E.J., Maund, A., Chan C.-H. (2006) Survey of Salmonella contamination of non-UK produced shell eggs onretail sale in the North West of England and London. http://www.food.gov.uk/multimedia/pdfs/nonukeggsreport.pdf

346.Hopkins, K.L., Arnold, C. & Threlfall, E.J. (2007) Rapid detection of mutations within the Quinolone-Resistance-Determining Region of gyrA in quinolone-resistant Salmonella enterica by



pyrosequencing. Journal of Microbial Methods, 68, 163-171.

347.Cooke, F.J., Day, M., Wain, J. & Threlfall, E.J. (2007) Cases of typhoid fever imported into England, Scotland and Wales, 2000-2003. Transactions of the Royal Society of Tropical Medicine andHygiene 101, 398-404.

348. Hopkins, K.L., Wootton, L., Day, M., & Threlfall, E.J. (2007) Plasmid-mediated quinolone resistance determinant qnrS found in Salmonella enterica strains isolated in England and Wales. Journal of Antimicrobial Chemotherapy 59, 1071-1075.

349. Pezzoli, R., Elson, R., Little, C., Fisher, I., Yip, H., Peters, T., Hampton, M., De Pinna, E., Coia, JE., Mather, H., Brown, D.J., Moller Nielsen, E., Ethelberg, S., Heck, M., de Jager, C. & Threlfall, E.J. (2007) International outbreak of Salmonella Senftenberg in 2007. Eurosurveillance Weekly 12, issue 6, 6-10.

350.Little, C.L., Surman-Lee, S., Greenwood, M., Bolton, F.J., Elson, R., Mitchell, R.T., Nichols. G.N., Sago, S.K., Threlfall, E.J. & Ward, L.R. (2007) Public health investigations of Salmonella Enteritidis in catering raw shell eggs, 2002-2004. Letters in Applied Microbiology, 44, 595-601.

351. Peters, T.M., Berghold, C., Brown, D., Coia, J., Dionisi, A.M., Echeita, A., Fisher, I.S.T., Gatto, A.J., Gill, N., Green, J., Gerner-Smidt P., Heck, M., Lederer, I., Lukinmaa, S., Luzzi,I., Maguire, C., Prager, R., Usera, M., Siitonen, A., Threlfall, E.J., Torpdahl, M., Tschäpe, H., Wannet, W. & Van Der Zwaluw, W.K. (2007) Relationship of pulsed-field profiles with key phage types of Salmonella enterica serotype Enteritidis in Europe: results of an international multi-centre study. Epidemiology & Infection, 135, 1274-1281.

352. Best, E., Lindstedt B.-A., Clifton-Hadley, F.A., Threlfall, E. J. & Liebana, E. (2007) Multiple-locus variable-number tandem repeat analysis of Salmonella enterica subsp. enterica serovar Typhimurium:comparison of isolates from pigs, poultry and cases of human gastroenteritis. Journal of Applied Microbiology 103, 565-572.

353. Threlfall, E. J. (2007) Salmonellosis – not just from bad eggs! Health Protection Matters, 8, 32-35.

354. Chart, H., Cheasty, T., de Pinna, E., Siorvanes, L., Wain, J., Alam, D., Nizami, Q., Bhutta, Z., & Threlfall, E.J. (2007) The serodiagnosis of human infections with Salmonella Typhi, S. Paratyphi A., S. Paratyphi B and S. Paratyphi C. Journal of Medical Microbiology, 56, 1161-1166.

355. Hopkins K.L., Maguire, C., Best, E., Liebana, E. & Threlfall, E.J. (2007) Investigation into the stability of Multiple-Locus Variable-Number Tandem-Repeats in Salmonella enterica serovars Typhimurium Journal of Clinical Microbiology 45, 3058-3061.

356. Kehrenberg, C., Hopkins, K.L., Threlfall, E.J. & Schwarz, S. (2007) Complete nucleotide sequence of a small qnrs1-carrying plasmid from Salmonella enterica subsp. enterica Typhimurium DT193. Journal of Antimicrobial Chemotherapy, 60, 903-905.

357.Cooke F.J., Wain, J., Fookes, M., Ivens, A., Thomson, N., Brown D., Threlfall, E.J., Gunn, G., Foster, G. & Dougan, G. (2007) Identification of hotspots of genome variation in wild Salmonella enterica serovar Typhimurium and their use to rapidly distinguish between different isolates from the same geographical region. Journal of Clinical Microbiology 45, 2590-2598.

358. Little, C.L., Walsh, S., Hucklesby, L., Surman-Lee, S., Pathak, K., Gatty, Y., Greenwood, M., de Pinna, E., Threlfall, E.J., Maund, & Chan, C.-H.(2007) Survey of Salmonella contamination of non-UK produced raw shell eggs on retail sale in the north west of England and London, 2005-2006 Journal ofFood Protection 70, 2259-2265.

359. Aktas, Z, Day, M., Bal, C., Diren, S. & Threlfall, E.J. (2007) Molecular characterization of Salmonella Typhimurium and Salmonella Enteritidis by plasmid analysis and pulsed-field gel electrophoresis. International Journal of Antimicrobial Agents, 30, 541-545.

360. Pezzoli,L Elson, R., Little, C.L., Fisher, I.S.T., Yip, H., Peters, T., Hampton, M.D., De Pinna, E., Coia, J.E., Mather, H.A., Brown, D.J., Nielson, E.M., Ethelberg, S., Heck, M., de Jager, C. & Threlfall, E.J. (2007). International outbreak of Salmonella Senftenberg in 2007. Eurosurveillance 12 (6): E070614.3.

361. Denny, J., Takkinen, J., Straetemans, M., Westrell, T., Varela, C., Threlfall, E.J., Adak, B., Boxall, N., Lofdahl, S., Ethelberg, S., Torpdahl, M. & van Pelt, W. (2007). Multinational Salmonella Paratyphi Bvariant Java (Salmonella Java) outbreak, August – December 2007. Euro surveillance 12 (12): December 2007.

362. Bale, J.A., De Pinna, E., Threlfall, E.J. & Ward, L.R. (2007) Salmonella identification: serotypes and antigenic formula. Kauffmann-White Scheme 2007. Health Protection Agency 2007. ISBN: 978-0-901144-91-1.362.

363. Hopkins K.L., Batchelor, M.J., Anjum, M, Davies R.H. & Threlfall, E.J. (2007) Comparison of antimicrobial resistance genes in non-typhoidal salmonellae of serotypes Enteritidis, Hadar and Virchow from humans and food-producing animals in England and Wales. Microbial Drug Resistance



13, 281-288.

364. Hopkins, K.L., Karisik, E., Wardle, J.K. & Threlfall, E.J. (2008) Identification of novel plasmid-mediated extended-spectrum -lactamase CTX-M-57 in Salmonella enterica serovar Typhimurium. International Journal of Antimicrobial Agents 31, 85-86.

365. Little, C.L., Rhodes, J.R., Hucklesby, L., Greenwood. M., Surman-Lee, S., Bolton, F.J., Meldrum, R., Wilson, I., McDonald, C., de Pinna, E., Threlfall, E.J. & Chan, C-H. (2008) Survey of Salmonella contamination of raw shell eggs used in food service premises in the United Kingdom, 2005 through to 2006. Journal of Food Protection 71: 19-26.

366.Threlfall, E.J. Infectious Diseases: Salmonella. In: International Encyclopaedia of Public Health, Volume 5.. Editors., Heggenhougen, K., Quah, S. Academic Press;, San Diego, USA 2008. pp 639-647.

367. Nygård, K., Lassen, J., Vold, L., Andersson, Y., Fisher, I., Löfdal, S., Threlfall, E.J., Luzzi, I., Peters, T., Hampton, M.D & Aavitsland, P. (2008) Outbreak of Salmonella Thompson infection linked to imported rucola lettuce. Foodborne Pathogens and Disease 2, 165-173.

368. Meakins, S., Fisher, I.S.T., Berghold, C, Gerner-Smidt, P., Tschäpe, H., Cormican, M., Luzzi, I., Schneider, F., Wannett, W., Coia, J., Echeita, A. & Threlfall E.J. (on behalf of Enter-net participants) (2008) Antimicrobial drug resistance in human non-typhoidal Salmonella isolates in Europe 2000-04: a report from the Enter-net international surveillance network. Microbial Drug Resistance 14, 31-35

369. Threlfall E,J., de Pinna, E., Day, M., Lawrence, J.,& Jones J. (2008) Alternatives to ciprofloxacin use for enteric fever, United Kingdom. Emerging Infectious Diseases 14, 860-861.

370. Pickard, D., Thomson, N.R., Baker, S., Wain, J., Churcher, C., Threlfall, E.J. & Dougan, G. (2008)Molecular characterisation of the Salmonella enterica serovars Typhi Vi typing bacteriophage E1. Journal of Bacteriology 190, 2580-2587

371. Hopkins, K.L., Day, M. & Threlfall, E.J. (2008) Plasmid-mediated quinolone resistance in Salmonella enterica in the UK. Emerging Infectious Diseases,14, 340-342.

372. Batchelor, M., Hopkins, K.L., Liebana, E., Slickers, P., Ehricht, R., Mafura, M., Aarestrup, F., Mevius, D., Clifton-Hadley, F.A., Woodward, M.J., Davies, R.H., Threlfall, E.J. & Anjum, M. (2008) Development of a miniaturised microarray based assay for the rapid identification of antimicrobial resistance genes from Gram-negative bacteria. International Journal of Antimicrobial Agents.31, 440-451.

373 Amar, C.F.L., Arnold, C., Bankier, A., Dear, P., Guerra Román, B., Hopkins, K.L., Liebana, E., Mevius, D.J.,& Threlfall, E.J. (2008) Real-time PCRs and fingerprinting assays for the detection and characterization of Salmonella Genomic Island-1 encoding multi-drug resistance: Application to 445 European isolates of Salmonella, Escherichia coli, Shigella and Proteus. Microbial Drug Resistance 14, 79-92.

374. Little, C.L., Richardson, J.F., Owen, R.J., de Pinna, E., and Threlfall, E.J. (2008) Campylobacter and Salmonella in raw red meats in the United Kingdom: Prevalence, characterisation and antimicrobial resistance pattern, 2003 to 2005. Food Microbiology, 25, 538-543.

375. Hopkins, K.L. & Threlfall, E.J. (2008) Epidemiology of multidrug resistant Salmonella Typhimurium DT104 infections. In: Molecular biology and molecular epidemiology of Salmonella infections. Editors, Calva, J.J., Calva, E., Pang, T., Maloy, S. Publishers: Research Signpost, USA. In press.

376. Little, C.L., Richardson, J.F., Owen, R.J., de Pinna, E., & Threlfall, E.J. (2008) Prevalence, characterization and antimicrobial resistance of campylobacter and salmonella in raw poultry meat in the United Kingdom, 2003 to 2005. International Journal of Environmental Health Research, 18, 403-414.

377..Pezzoli, L., Elson, R., Little, C., Yip, H., Fisher, I.S.T., Yishai, R., Anis, E., Valinsky, L., Biggerstaff, M., Patel, N., Mather, H., Brown, D.J., Coia, J.E, van Pelt, W., Nielsen, E.M., Ethelberg, S., de Pinna, E., Hampton, M.D, Peters, T., & Threlfall, E.J. (2008) Packed with Salmonella - Investigation of an international outbreak of Salmonella Senftenberg infection linked to contamination of pre-packed basil.Foodborne Pathogens and Disease 5, 661-668.

378. Denny, J., Hernandez-Perez, G., Threlfall, E.J. & Fisher, I.S.T. (2008) A quarterly update on food and waterborne diseases in Europe. Summary of 3rd quarter, 2007. Salmonella, VTEC, Campylobacter. Euro Surveillance, 13 (11);pii=8069

379. Parry, C.M. & Threlfall, E.J. (2008) Antimicrobial resistance in typhoidal and non-typhoidal salmonellae. Current Opinions in Infectious Diseases 21, 531-538.

380. Elviss, N.C., Little, C.L., Hucklesby, L., Sagoo, S. Surman-Lee, S., de Pinna, S. & Threlfall, E.J. (2009). Microbiological study of fresh herbs from retail premises uncovers an international outbreak of



salmonellosis. International Journal of Food Microbiology, 134, 83-88.

381. Sagoo, S.K., Little, C.L., Greenwood M., Mithani, V., McLauchlin, J., de Pinna, E., & Threlfall, E.J.(2009) Assessment of the microbiological safety of dried spices and herbs from production and retail premises in the United Kingdom. Food Microbiology 26, 39-43. 379.

382. Kafatos, G., Andrews, N., Gillespie, I.A., Charlett, A., Adak, G.K., de Pinna, E. & Threlfall, E.J. (2009) Impact of reduced numbers of isolates phage-typed on the detection of Salmonella outbreaks. Epidemiology & Infection, 137, 821-827.

383. Threlfall, E.J. (2009) Resistant gut bacteria. In: Manson’s Tropical Diseases, 22nd Edition. Editors, Cook, G.C., Zumla, A.I.. Saunders Elsevier. pp, 943-952.

384. Threlfall, E.J. (2009) Current thinking on resistance and antibiotic therapy of enteric fevers. Drugsand Bugs, 13, 7-8.

385. Lake, I.R., Gillespie, I.A., Bentham, G., Nichols, G.L., Lane, C., Adak, G.K., & Threlfall, E.J. (2009) A re-evaluation of the impact of temperature and climate change upon foodborne illness. Epidemiology &Infection 2009 Apr 17. E pub ahead of print.

386. Herrero, A., Mendoza, M.C., Threlfall, E.J. & Rodicio, M. (2009) Detection of Salmonella enterica serotype Typhimurium with pUO-StVR2-like2 virulence-resistance hybrid plasmids in the United Kingdom. European Journal of Clinical Microbiology and Infectious Diseases, May 2009 e pub ahead of n press

387. Cooke F.J., De Pinna, E., Maguire, C., Guha, S., Picard D.J., Farrington, M. & Threlfall E.J. (2009) First report of human infection with Salmonella enterica serovar Apapa, associated with a pet lizard. Journal of Clinical Microbiology 47, 2672-2674.

388. Threlfall, E.J. (2009) Med-Vet-Net, a European Union network for zoonotic research Med-Vet-Net– a network for the prevention and control of zoonoses. Health Protection Report 3, No. 33, 6-7.

389. Best E.L., Hampton, M.D., Ethelberg, S., Liebana, E., Clifton-Hadley, F.A. & Threlfall, E.J. (2009) Porcine-associated Salmonella Typhimurium DT120: use of PFGE and VNTR in a putative international outbreak investigation. Microbial Drug Resistance , 15: 133-138.

390. Threlfall, E. J. (2009) Antimicrobial resistance in bacterial enteric pathogens. Microbiologist 10, 24-27.

391. Threlfall, E.J. & Belcher, T. (2009) Med-Vet-Net – the EU Network for the prevention and control of zoonoses . Parliamentary Magazine 289, 18.

392. Grecko, C., Badiola, J.I., Catry, B., van Dujikeren, E., Moreno, M., Matias Ferria Pombo, M.C., Pyorala, S., Ruzaukas, M., Sanders, P., Threlfall, E.J., Ungemach, F., Torneke, K., Torren-Edo, J. (Scientific Advisory Group on Antimicrobials of the Committee for Medicinal Products for Veterinary Use - SAGAM (2009). Reflection paper on the use of third and fourth generation cephalosporins in food producing animals in the European union: development of resistance and impact on human and animal health. Journal of Veterinary Pharmacology and Therapeutics, 32. 515-533. doi: 10.1111/j.i365-2885.2009.01075.x

393. Willis, C., Little, C.L., Sagoo, S., de Pinna, E. & Threlfall, E.J. (2009) Assessment of the microbiological safety of edible dried seeds from retail premises in the United Kingdom with a focus onSalmonella spp. Food Microbiology 26, 847-852.

394. Hammer J.A., Beutlich, J., Hertwig, S., Mevius, D., Threlfall, E.J. Helmuth, R & Guerra, B.(2009) pSGI15, a small ColE qnrB19 plasmid of a Salmonella enterica serovar Typhimurium strain carrying the Salmonella Genomic Island 1 (SGI1). Journal of Antimicrobial Chemotherapy, 2010; 65:173-175.

395. Hendriksen, R.S., Mikoleit, M., Kornschober, C., Rickert, R.L., Duyne, S.V., Kjelsø ,C., Hasman, H., Cormican, M., Mevius, D., Threlfall, E.J., Angulo, F.J. & Aarestrup, F.M.. (2009) Emergence of multidrug-resistant Salmonella Concord infections in Europe and the United States in children adoptedfrom Ethiopia, 2003-2007. Paediatric Infectious Disease Journal 28, 814-818.

396. Bhutta, Z.A. & Threlfall, E.J. (2009) Addressing the global disease burden of typhoid fever. Journal of the American Medical Association (JAMA), 302, 898-899.

397. Catry, B. & Threlfall, E.J. (2009) Critically-important antimicrobial - or not? Clinical Infectious Diseases, 2009; 49: 1961.

398. Ben-Darif, E , De Pinna, E , Threlfall, E.J., Bolton , F.J., Upton, M. & Fox, A.J. (2010) Comparisonof a semi-automated rep-PCR system and multilocus sequence typing for differentiation of Salmonellaenterica isolates. Journal of Microbial Methods, 81, 11-16.

399. Ben-Darif, E , Jury, F., De Pinna, E , Threlfall, E.J., Bolton , F.J., Fox, A.J.& Upton, M. (2010) Development of a multiplex primer extension assay for detection of Salmonella serotypes directly fromspecimens. Journal of Clinical Microbiology, 48, 1055-1060.

400. Catry, B., van Duijkeren, E., Matias, M.C., Pomba, F., Badiola, J.I., Greko, C., Moreno, M.A.,



Pyörälä, S., Ružauskas, M, Sanders, P., Threlfall, E.J., Ungemach, F., Törneke, K. & Torren-Edo, J. (2010) Reflection paper on MRSA in food producing and companion animals: epidemiology and control options for human and animal health. Epidemiology & Infection 138, 626-644.

401. Lucarelli., C., Dionisi, A.M., Torpdahl, M., Villa, L., Grazianai, C., Hopkins, K.L., Threlfall, E. J., Caprioli, A.& Luzzi. I .(2010) Evidence for a second genomic island conferring multidrug resistance in a clonal group of strains of of Salmonella enterica serovar Typhimurium and its monophasic variant (S.enterica 4,[5],12:i) circulating in Italy, Denmark and the United Kingdom. Journal of Clinical Microbiology, 48, 2103-2109.

402. Hopkins K.L., Kirchner, M., Guerra B., Granier, S.A., Lucarelli, C., Porrero, M.C., Jakubczak A, Threlfall, E.J. & Mevius, D. (2010) Multiresistant Salmonella enterica serovar 4,[5],12:i:- in Europe: a new pandemic strain? Euro Surveillance 2010;15(22):pil=19580. Available on line at: http;//www.eurosurveillance.org

403..Newell, D.G., Koopmans, M., van der Giessen, J., Kruse, H., Aidara-Kane, A., Sprong, H., Opsteegh, M., Langelaar, M., Kortbeek, L.M., Threlfall, E.J. & Scheutz, F.(2010) Food borne diseases – the challenges of 20 years still persist while new ones continue to arise. International Journal of Food Microbiology 139, S3-S15.

404. Williams, M., Ridley, A., Hoszowski, A. & Threlfall, E.J. (2010) Multidrug-resistant Salmonella Virchow –not just a local problem? International Journal of Antimicrobial Agents, submitted.

405.Lane, C, de Pinna, E., Connell, S., Wain, J., Davies, R.H., & Threlfall E.J. (2010) Resistance to critically–important antimicrobials in Salmonella from cases of human infection in England and Wales, 2000-2009 International Journal of Antimicrobial Agents, submitted.

406. Lane C, Threlfall E.J. & Kaftos, G. (2010) Trends in Salmonella reporting, England and Wales 1981 – 2009 ; Twenty- nine years of salmonella infections in England and Wales. In: i3S - InternationalSymposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2010. pp 329-332.

407 Williams, M., Ridley, A., Hoszowski, A. & Threlfall, E.J. (2010) Multidrug-resistant Salmonella Virchow –not just a local problem? In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2010.

408. Money, P., Kelly, A.F., Gould, S.W.J., Denholm-Price, J, Threlfall, E.J., & Fielder, M.D. (2010) Cattle, weather and water: Mapping Escherichia coli O157:H7 infections in humans. Environmental Microbiology 10, 2633-2644.

409. Beutlich, J., Rodicio, M. R., Mendoza, M.C., Kirchner, M., Luzzi, I., Mevius, D., Threlfall, E.J., Helmuth, R., & Guerra, B. (2010). Salmonella enterica subsp. enterica serovar Typhimurium isolates collected within the European Project Med-Vet-Net (workpackage 21) carry virulence resistance plasmids derived from the pSLT90. In: i3S - International Symposium, Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2010. pp 159-161

410. Beutlich, J., Jaber, M., Thomas, K., Schroeter, A., Granier, S., Herrera leon, S., Hopkins, K., Luzzi, I., Adrian, E., Szych, J., Torpdahl, M., 403. Threlfall, E.J., Wain, J. & Lane, C. (2011) Salmonellosis. In : Zoonoses, Second edition. Editor, Palmer, S.R., Soulsby, L., Torgerson, P.R., Brown, D.W.G. Oxford University Press 2011. pp. 252-262.

411.Veldman, K., Wu, G., Appel, B., Threlfall, E,J., Mevius, D., Helmuth, R. & Guerra, B. (2010). Salmonella Genomic Island 1 variants in Salmonella enterica subsp. enterica serovar Newport isolates collected within the European project Med-Vet-Net (WP21). In: i3S - International Symposium,Salmonella and Salmonellosis. Proceedings. Editors, Colin, P., Clement, G. Zoopole - ISPAIA, 2010. pp 179-180.

412. Threlfall, E.J., Wain, J. & Lane, C. (2011). Salmonellosis. In : Zoonoses, Second edition. Editor, Palmer, S.R., Soulsby, L., Torgerson, P.R., Brown, D.W.G. Oxford University Press 2011. pp. 252-262.

413. Le Hello, S., Hendriksen, R.S., Doublet, B., Fisher, I., Nielsen, E.M., Whichard, J.M., Bouchrif, B., Fashae, K., Granier, S.A., Jourdan-Da Silva, N., Cloeckaert, A., Threlfall, E.J., Angulo, F.J., Aarestrup, F.A., John, J. & Weill, F.-X. (2011). The international spread of an epidemic clone of Salmonella enterica serotype Kentucky resistant to ciprofloxacin. Journal of Infectious Diseases 204, 675-684.

414. Beutlich, J, Jahn, S., Malorny, B., Hauser, E., Hühn, S., Schroeter A., Rosario, R., Appel, B., Threlfall, E.J., Mevius, D., Helmuth. R. & Guerra B., on behalf of the Med-Vet-Net WP21 Project Group. (2011) Antimicrobial Resistance and Virulence determinants in European “Salmonella Genomic Island 1 (SGI1)” positive Salmonella enterica isolates from different origins. Applied and Environmental Microbiology 77, 5655-5664

415. van Duijkeren, E., Catry, B., Greko, C., Moreno, M.A., Pomba, M.C., Pyörälä, S., Ruzauskas, M., Sanders, P., Threlfall, E.J., Törneke, K. & Torren-Edo J; Scientific Advisory Group on Antimicrobials (SAGAM). (2011) Review on meticillin-resistant Staphylococcus pseudintermedius. Journal of



Antimicrobial Chemotherapy 12, 2705-2714.

416. Threlfall, E.J., Wain, J., Peters, T.M., Lane, C., De Pinna, E., Little, C.L., Wales, A. & Davies, R.H.2014. Egg-borne infections of humans with Salmonella: not only an S. enteritidis problem. World’s Poultry Science Journal, in press

417. Beutlich, J, Rosario, M.R., Mendoza, M.C., Garcia, P., Kirchner, M., Mevius, D., Threlfall, E.J., Helmuth, R., & Guerra, B., on behalf of the Med-Vet-Net WP21 Project Group (2013). Salmonella serovar Typhimurium virulence-resistance plasmids derived from the pSLT-carrying non-conventional class 1 integrons with dfrA12 gene in their variable region and sul3 in the 3`conserved segment. Microbial Drug Resistance, 19, 437-445. E pub ahead of print June 14 2013

418. García, P., Hopkins K.L., García, V., Beutlich, J., Carmen Mendoza M.C., Threlfall E.J., Mevius, D., Helmuth, R., Rosario Rodicio, M.R. & Guerra, B., on behalf of the Med-Vet-Net WP21 project group. (2014) .Diversity of plasmids encoding resistance and virulence functions in Salmonella Typhimurium 4,[5],12:i:- strains circulating in Europe. PLoS One, in press

419. Liebana, E., Carattoli, A., Coque, T.M., Hasman, H., Magiorakos, A.P., Mevius, D., Peixe, L., Poirel, L., Schuepbach-Regula, G., Torneke, K., Torren, J., Torres, C., & Threlfall, E.J.. (2013) The public health risks of enterobacterial isolates producing extended-spectrum β-lactamases (ESBL) and/or AmpC β-lactamases in food and food-producing animals: An EU perspective of epidemiology, analytical methods, risk factors and control options. Clinical Infectious Diseases, 56, 1030-1037.

420. Wu ,G., Day M.J, Mafura, W.T., Nunez-Garcia, J.,. Fenner, J.J., Sharma, M., van Essen-Zandbergen, A., odríguez-Fernandez, I., Dierikx, C., Kadlec, K., Schink, A.-K., Wain, J., Helmuth, R., Beatriz Guerra, B., Schwarz, S., Threlfall, E.J., Woodward, M.J., Woodford, N., Coldham, N.& Mevius,D. (2013) Comparative analysis of ESBL-positive Escherichia coli isolates from animals and humans from the UK, The Netherlands and Germany” PLoS One. Available at: nhttp://dx.plos.org/10.1371/journal.pone.0075392

421 Maillard, J.- Y., Bloomfield, S., Rosado Coelho, Collier, P., Cookson, B., Fanning, S., Hill, A., Hartemann, P., McBain, A., Oggioni, M., Sattar, S., Schweizer, H.P &, Threlfall,.E.J. (2013) Does microbicide use in consumer products promote antimicrobial resistance? A critical review and recommendations for a cohesive approach to risk assessment. Microbial Drug Resistance 19, 344-354..June 14 2013. E pub ahead of print,

422 Rodríguez, I., Thomas, K., Van Essen, A., Schink, A.K., Day, M., Chattaway, M., Wu, G., Mevius, D., Helmuth, R. & Guerra, B., on behalf of the SAFEFOODERA-ESBL consortium (Woodward, M.J., Coldham, N., Kadlec, K., Schwarz, S., Threlfall, E.J., Woodford, N., Wain, J. & Dierikx, C). (2014). Chromosomal location of blaCTX-M genes in clinical isolates of Escherichia coli from Germany, The Netherlands and the UK. International Journal of Antimicrobial Agents, 43, 553-557.

423.. Mendoza, N. & Threlfall, E.J. (2014). Antimicrobial resistance – a real and present danger. Microbiologist 15, 22-24.

424 .Pyörälä S, Baptiste KE, Catry B, van Duijkeren E, Greko C, Moreno MA, Pomba MC, Rantala M,Ružauskas M, Sanders P, Threlfall EJ, Torren-Edo J, & Törneke K. (2014) Macrolides and lincosamides in cattle and pigs: Use and development of antimicrobial resistance. Veterinary Journal 200, 230-239.

425. Butaye P, Argudín, M.A &, Threlfall, E.J. (2015) Introduction to antimicrobial resistant food-borne pathogens.. In: Antimicrobial Resistance and Food Safety: Methods and Techniques. Editors: Chin-Yi Chen, Xianghe Yan, and Charlene Jackson. Elsevier, Inc. Academic Press, 2015

426. Ricci, A, Felicio, M.T., Vivas-Alegre, L., Butaye P., Davies R.H., Hald T., Havelaar, A., Lindstedt, B.-A., Miden, M., Nielsen, E.M., Scavia, G., Struelens, M., Threlfall, J &, Baggesen, D.L.(2015) Molecular typing methods for major food-borne microbiological hazards and their use for attribution modelling, outbreak investigation and scanning surveillance.

427. Messens, W., Bolton, D., Frankel, G., Liebana, E., McLauchlin, J., Morabito, S., Oswald, E. & Threlfall, E.J. (2015) Defining pathogenic Verocytotoxin-producing Escherichia coli (VTEC) from casesof human infection in the European Union, 2007-2010. Epidemiology & Infection 143, 1652-1661.

428. Catry, B., Cavaleri, M., Baptiste, K., Grein, K., Holm, A., Jukes, H., Liebana, E., Lopez Navas, A. MacKay, D., Magiorakos, A.-P., Monnet, D., Moreno, M. A. R., Moulin, G., Muñoz Madero, C., Pomba,C., Powell, M, Pyörälä, S.,Rantala, M., Ružauskas, M., Sanders, P., Teale, C., Threlfall, E. J., Törneke,K.,Van Duijkeren, E.& Torren Edo, J. (2015) Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health. International Journal of Antimicrobial Agents 46, 297-306.

429. Day, M.J., Rodríguez, I van Essen-Zandbergen, A., Dierikx, C., Kadlec, K., Schink, A.-K., Wu, G.,Chattaway, M.A., DoNascimento, V., Wain, J., Helmuth, R., Guerra, B., Schwarz, S., Threlfall, E.J., Woodward, M.J., Coldham, N., Mevius, D., & Woodford, N (2016) (on behalf of the SAFEFOODERA consortium). .Diversity of sequence types, phylogroups, plasmids and extended-spectrum β-



lactamase genes among Escherichia coli from humans, animals and food in Germany, Netherlands and United Kingdom. Journal of Antimicrobial Chemotherapy 71, 1178-1182.

430..Pomba, C.M.F., Rantala, M., Greko, C., Pringle, M., Baptiste, K.E., Boudewijn C., , van Duijkeren.E Jukes, H., Moreno, M.A., Pyorala, S., Ruzauskas, M., Sanders, P., Teale, C., Threlfall, E.J., Kunsangi, Z., Torren-Edo, J., & Torneke, K. (2016) The public health risk of antimicrobial resistance transfer from companion animals. Journal of Antimicrobial Chemotherapy, 2016 Dec 20. pii: dkw481. doi: 10.1093/jac/dkw481. [Epub ahead of print]

431. Gunn, L., Finn, S., Hurley, D., Bai1 L., Wall, E., Iversen, C., Threlfall, E.J. & Fanning, S. (2016) Molecular characterisation of Salmonella serovars Anatum and Ealing associated with two historical outbreaks linked to contaminated powdered infant formula. Frontiers in Microbiology, 1664. E Collection 2016.

432. EMA Committee for Medicinal Products for Veterinary Use (CVMP) and EFSA Panel on Biological Hazards (BIOHAZ), Murphy, D., Ricci, A., Auce, Z., Beechinor, J. G., Bergendahl, H., Breathnach, R., Bureš, P.D., Da Silva, J. Hederová, J., Hekman, P., Ibrahim, C., Kozhuharov, E., Kulcsár, G., Persson, E. L., Lenhardsson, J. M., Mačiulskis, P., Malemis, I., Markus-Cizelj, L., Michaelidou-Patsia, A., Nevalainen, M., Pasquali P., Rouby, J.-C., Schefferlie, W., Schlumbohm, W., Schmit, M. Spiteri, S., Srčič, S., Taban, L., Tiirats, T., Urbain, B. Vestergaard, E-M., Anna Wachnik-Święcicka, A., Weeks, J., Zemann, B., Allende, A., Bolton, D., Chemaly, M., Escamez, P.S.M., Girones, R., Herman, L., Koutsoumanis, K, Lindqvist, R., Nørrung, B., Robertson, L., Ru, G., Sanaa, M., Simmons, M., Skandamis, P., Snary, E., Speybroeck, N., Ter Kuile, B., Wahlström, H., Baptiste, K.,Catry, B., Cocconcelli P.S., Davies, R., Ducrot, C., Friis, C., Jungersen, G., More, S., Muñoz Madero, C., Sanders, P., Bos, M., Kunsagi, Z., Torren Edo, J., Brozzi, R., Candiani, D., Guerra, B., Liebana, E., Stella, P., Threlfall, E.J. & Jukes, H. (2017). EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial agents in animal husbandry in the European Union, and the resulting impacts on food safety (RONAFA). EFSA Journal 2017, in press.

Projects PI in ca. 30 non-commercial Grant-funded projects, 1990-2010 (UK and EU-based)

Project Director, EU-funded Enternet Network, 2004-2008

Project Director, EU-funded NoE 'Med-Vet-Net, 2008-2011

Project Manager, EU-funded (DG SANCO, ECDC) EURLOP and EU-LabCAT Projects, 2010-2013

Memberships Member, Association of Clinical Biochemists, UK

Member, Society for Applied Microbiology, UK (Committee member from July 2013-present)

Institut Pasteur d' Algerie, Algeria. Honorary Consultant in Microbiology 1979 - 2010

Commission of European Communities (CEC):

Invited Expert (Antibiotic resistance) 1982, 1984, 1986

Robert Koch-Institut, Germany. Invited Expert 1996 -2004

World Health Organisation. Invited Expert, Antimicrobial drug resistance 1997 -2010

American Water Works Association - Research Foundation, USA.

Member, Project Advisory Committee (PAC) – molecular typing 1997 - 2004

Alliance for the Prudent Use of Antibiotics. Member, Scientific Advisory Board 1999 - present

Enternet (EU-funded network for Salmonella, VTEC and Campylobacter

Representative for England and Wales 1998 - 2007

Project Leader 2005 - 2007

Defra Microbial Antibiotic Resistance Co-ordination (DARC) Group:

Representative for HPA 1999 - 2010

Office International Epizootique , Ad Hoc Group on Antibiotic Resistance

Representative for UK 2000 - 2004

Advisory Steering Committee, Swiss National Research Programme, “Antibiotic Resistance”

Member and Scientific Advisor 2000 - present

Department for Environment, Foods and Rural Affairs (Defra)

Member, Veterinary Fellowship Assessment Panel 2000 - 2004



Visiting Professor, University of Cork 2002- present

ROAR II (Reservoirs of Antibiotic Resistance) Member, Steering Committee 2002 - 2008

FAO/WHO/OIE: Member, consultation group on antimicrobial drug resistance 2003 -2004, 2007

European Food Safety Authority: Member, Specialist WG on Antimicrobial Resistance 2003 -2004

Veterinary Laboratories Agency -External Scientific Programmes Assessor 2004 - 2010

International Federation of Enteric Phage Typing (IFEPT) Co-chairman 2005 -2010

WHO Global Salm-Surv; (GSS) Member, Steering Committee 2005 – 2010

Visiting Professor (Honorary Faculty member), University College Dublin 2008 – present

European Food Safety Authority: member, WG on AMR in Food Chain 2008 – 009

European Food Safety Authority: member, joint drafting group on GMOs

and food safety in relation to antimicrobial resistance 2008 – 2010

European Centre for Disease Control (ECDC). Consultant in GI Disease 2008 - 2010

Med-Vet-Net; Project Director 2008 - 2010

Med-Vet-Net Association; Project Director 2009 -2010

Member, EFSA BIOHAZ panel, 2009 - 2016

Editorial Board Member, ca 10 journals, 1984-current

Over 200 invited presentations at national and international scientific meetings, 1979-2016.

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PERSONAL INFORMATION Eric John Threlfall · PERSONAL INFORMATION Eric John Threlfall ... EU-funded EURLOP and EU-LabCAT projects ... antimicobial drug resistance,