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Diagnostic Radiology of Diagnostic Radiology of Cardiovascular System Cardiovascular System Chen, Shaoqiong Acknowledgement : most of the slices are refer to the ppt provided by Dr. Biling Liang is gratefully acknowledged

Pericardial abnormal findings

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Page 1: Pericardial abnormal findings

Diagnostic Radiology ofDiagnostic Radiology ofCardiovascular SystemCardiovascular System

Chen, Shaoqiong

Acknowledgement : most of the slices are refer to the ppt provided by Dr. Biling Liang is gratefully

acknowledged

Page 2: Pericardial abnormal findings

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Basic X-ray featuresBasic X-ray features

Heart dislocation

Heart enlargement

Abnormal pulmonary blood flow

Changes of aorta

Pericardial abnormal findings

methods

normal

abnormities

diseases

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Basic X-ray featuresBasic X-ray features

Changes of pericardiumChanges of pericardium

Normal pericardium

Pericardial anomalies

Pericardial effusionAcute pericarditis

Pericardial thickening 、 calcification

Chronic pericarditis

Constrictive pericarditis

methods

normal

abnormities

diseases

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Basic X-ray featuresBasic X-ray features

Changes of pericardiumChanges of pericardium

Normal pericardium

methods

normal

abnormities

diseases

Page 5: Pericardial abnormal findings

Normal pericardium

Inner serous layer  is the epicardium Outer fibrous layer is pericardium Space between the two is pericardial space Normally contains about 20-50cc of fluid Fat covers outside of heart and outside of pericardium sandwiching pericardial space between the two layers

Normal thickness of pericardium (parietal pericardium and fluid in space) is 2-4 mm

Requires about 150-250cc before cardiac tamponade occurs

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Basic X-ray featuresBasic X-ray features

Changes of pericardiumChanges of pericardium

Normal pericardium

Pericardial anomalies

Pericardial effusionAcute pericarditis

Pericardial thickening 、 calcification

Chronic pericarditis

Constrictive pericarditis

methods

normal

abnormities

diseases

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Pericardial effusionPericardial effusionX-ray appearance:

Direct sign:Heart shadow generally enlarge bilaterally “water-bottle” or “flask” shape, globularContour of cardiac border disappearPulsation of the cardiac border weaken or disappear, but the aortal pulsation is normal

Indirect sign:Vena systemica return obstructed, right ventricle output decreased

Superior vena cava widenDecreased lung markings

Aortal shadow smaller

Cardiac tamponade – impedes diastolic filling

methods

normal

abnormities

diseases

Tuberculosis rheumatism

uraemia virus neoplasm

Fluid: Transudation exudation blood

Page 8: Pericardial abnormal findings

Pericardial effusionPericardial effusion

Pericardial effusion on both lateral chest radiograph and axial CT. Red arrow points to fat outside of pericardium. Green arrow points to pericardial space which is 8 mm in this patient (<4 mm is normal.)  The  yellow arrow  points to fat outside of heart and the blue arrow to the myocardium.

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Pericardial effusionPericardial effusion

Page 10: Pericardial abnormal findings

Pericardial effusionPericardial effusion

methods

normal

abnormities

diseases

“water-bottle” “flask” shape Globular shape

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Pericardial effusionPericardial effusionmethods

normal

abnormities

diseases

general enlarge

bilaterally

Widened SVCWidened SVC

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Pericardial effusionPericardial effusion

erect positionerect position supine positionsupine position

methods

normal

abnormities

diseases

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Pericardial thickening 、 calcificationthickening:

Pericardium near the diaphragm (ventricular face) thicken obviously but the atrium aera and the root of the great vessels less thickenEpicardial fat pad ‘sign’ (+)

Lat. / PA view: anterior pericardial stripe > 2mm

Hemodynamic change:Right ventricle compression : venous return obstructed, vena cervicalis and vena cava dilatationLeft ventricle compression : left atrium and pulmonary venous pressure increased, so the left heart output decreased

methods

normal

abnormities

diseases

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Constrictive pericarditisConstrictive pericarditisX-ray :

Direct sign:The heart shadow size is normal or little, midium enlarged

A side or both sides of heart borders straighten, the demarcation among each arcus is undefined; contour: triangle , globular

Heart pulsation weaken or disappear; the portion without thickened can bulge, and it’s pulsation enhanced

Pericardial calcification : eggshell, barred, patching,

Pleural thickening, adhesion

Indirect sign : VP ↑Superior vena cava dilatation

Pulmonary venous hypertension

methods

normal

abnormities

diseases

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Constrictive pericarditisConstrictive pericarditismethods

normal

abnormities

diseases

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Pericardial calcification

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Constrictive pericarditisConstrictive pericarditis - - RA enlargementRA enlargement

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Constrictive pericarditisConstrictive pericarditis - RA enlargement - RA enlargement

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Constrictive pericarditisConstrictive pericarditis - - RA enlargementRA enlargement

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Diagnostic Radiology ofDiagnostic Radiology ofCardiovascular SystemCardiovascular System

Imaging methods

normal appearances

abnormities

diseases

methods

normal

abnormities

diseases

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Common disease Common disease of heart and great vessels of heart and great vessels

Rheumatic heart disease

Mitral stenosis

Mitral regurgitation

Ischemic heart disease Ischemic heart disease

Coronary artery diseaseCoronary artery disease

Congenitial heart disease

ASDASD

Tetralogy of FallotTetralogy of Fallot

method

normal

abnormities

diseases

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Rheumatic heart diseaseRheumatic heart disease

Involved valve:Mitral valve 、 Aortic valve 、 Tricuspid

valve

Pathology:Mitral valve stenosisMitral valve stenosis: Valve ring

cicatricle contraction

Mitral valve insufficiencyMitral valve insufficiency:

methods

normal

abnormities

diseases

Page 23: Pericardial abnormal findings

Mitral StenosisRheumatic Valvular Heart Disease

● Rheumatic heart disease causes mitral stenosis in 99.8% of cases

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Right Ventricular Hypertrophy

Stenotic mitral valve

© Frank Netter, MD Novartis®

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• Mitral stenosis occurs

• Left atrial pressure

• Left atrium enlarges

• Cephalization

• PIE

• PAH develops

• PVR increases

• RV enlarges

• Pulmonic regurg develops

• Tricuspid annulus dilates

• Tricuspid insufficiency

• RV failure

Time course of MS in adult

© Frank Netter, MD Novartis®

Page 26: Pericardial abnormal findings

● Pulmonary venous and capillary pressure

Normal 5-10 mm Hg

Cephalization 10-15 mm

Kerley B Lines 15-20

Pulmonary Interstitial Edema 20-25

Pulmonary Alveolar Edema > 25

Effect of Mitral Stenosis On Lungs

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Mitral stenosis hemodynamics

Mitral valve stenosis

Left atrial output obstructed

LV engorge insufficientlyLA pressure increase & dilate

Pulmonary venous hypertension, interstitial pulmonary edema

RV burden increase & enlarge

aortic knob shrink

LV and aortic knob shrink

methods

normal

abnormities

diseases

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Mitral stenosisMitral stenosisX-ray appearance:

Cardiac type:“mitral configuration”LA & RV enlarged

------- pulmonary artery segment Convexity

LV shrink, Straightening of left heart border

------- Aortic knob shrink

valvular calcification

Pulmonary venous hypertension, interstitial pulmonary edema

Hemosiderin deposited : 1-2mm nodular shadow

methods

normal

abnormities

diseases

LA enlargementPA – right border : Double density of left atrial enlargement,,doublePA – left border : left atrial appendage enlargement Lat & RAO : esophagus compressed Elevation of left mainstem bronchus RV enlargementpulmonary artery segment Convexity Lat : contact between the front surface of heart and the sternum (anterior chest wall) >1/3

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Mitral stenosisMitral stenosis

Four arus, diplopia, Pulmonary venous hypertension

methods

normal

abnormities

diseases

LA enlargement PA – right border : double density PA – left border : left atrial appendage enlargement Lat & RAO : esophagus compressed

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Mitral stenosisMitral stenosis

LALALVLV

RVRV

LA

LV

LVLV

LALA

Valve calcification

LatLat

Cor Cor

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Mitral stenosisMitral stenosis

LALA

LVLV

LALALVLV

LALA

RVRV

LVLVRARA

RVRV

Page 32: Pericardial abnormal findings

Mitral stenosisMitral stenosis

LALA

LVLVLVLV

LALA

RVRV

RARA

Page 33: Pericardial abnormal findings

Mitral stenosisMitral stenosis

LA,RV enlarge, Hemosiderin pigmentation

methods

normal

abnormities

diseases

RV enlargementpulmonary artery segment Convexity Lat : contact between the front surface of heart and the sternum (anterior chest wall) >1/3

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Mitral stenosisMitral stenosismethods

normal

abnormities

diseases

Page 35: Pericardial abnormal findings

Mitral stenosisMitral stenosis

LA enlarge : esophagus compression, diplopiaRV enlarge: heart touch the anterior chest wall > 1/3

methods

normal

abnormities

diseases

LA enlargementPA – right border :double densityPA – left border : left atrial appendage enlargementLat & RAO : esophagus compressed

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Mitral stenosisMitral stenosismethods

normal

abnormities

diseases

PV hypertension enlarged MPA Cephalization

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Mitral stenosis --- Mitral stenosis --- Hemosiderin deposited

methods

normal

abnormities

diseases

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Mitral stenosis—pulmonary interstitialMitral stenosis—pulmonary interstitial edema-- Kerley’s B-line edema-- Kerley’s B-line

methods

normal

abnormities

diseases

Perpendicular to the chest wallPerpendicular to the chest wall

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Common disease Common disease of heart and great vessels of heart and great vessels

Rheumatic heart disease

Mitral stenosis

Mitral regurgitation

Ischemic heart diseaseIschemic heart disease

Coronary artery diseaseCoronary artery disease

Congenitial heart disease

ASDASD

Fallot 4Fallot 4

method

normal

abnormities

diseases

Page 40: Pericardial abnormal findings
Page 41: Pericardial abnormal findings

Coronary artery diseaseCoronary artery disease

Myocardium O2 supply insufficient

Caused by severe coronary artery stenosis

Atherosclerosis , spasm , thrombosis

Myocardial infarction

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Coronary artery CTA

MIP

With Contrast Medium

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VRT Recon.

Normal Coronary artery CTA

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前降支和旋支 前降支和对角支

前降支和旋支 心底部冠脉供血

正常冠脉MIP

重建

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正常冠状动脉

CT:119148

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Ischemic heart diseaseIschemic heart disease

methods

normal

abnormities

diseases

LV enlargement PA – cardiac apex extending to left and down left ventricle segment extended,rounded,expand to left Lat : retrocardiac space become narrowed or disappeared, esophageal space disappeaered

Aorta enlarged

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Ischemic heart diseaseIschemic heart disease

methods

normal

abnormities

diseases

cardiomegalycardiomegaly

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Multi-slice spiral CTmethods

normal

abnormities

diseases

Plain scan

Calcification in the coronary A. wall

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Coronary artery CTA

Negative prediction 100%

positive prediction 80 ~ 88%

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Coronary artery calcification & soft plaque

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Coronary artery soft plaque

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Coronary artery stenosis

DSA

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Myocardial infarctionMyocardial infarction

methods

normal

abnormities

diseases

Real time : infarcted Real time : infarcted myocardium non-enhancedmyocardium non-enhanced

Delay enhancement in the Delay enhancement in the infarcted myocardiuminfarcted myocardium

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Common disease Common disease of heart and great vessels of heart and great vessels

Rheumatic heart disease

Mitral stenosis

Mitral regurgitation

Ischemic heart disease Ischemic heart disease

Coronary artery diseaseCoronary artery disease

Congenitial heart disease

ASDASD

Fallot 4Fallot 4

method

normal

abnormities

diseases

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Congenital heart diseaseCongenital heart disease

Classification:Hemodynamics : left to right shunt, right to left shunt, no shunt

Clinic : cyanotic, non- cyanotic

X-ray: increased pulmonary blood flow , pulmonary oligemia, LBV no change

pathological changes:Atrial septal defect ( ASD)Ventricualr septal defect ( VSD)Tetralogy of Fallot ( F4)Patent ductus arteriosus ( PDA)Pulmonary stenosis ( PS)

method

normal

abnormities

diseases

Page 57: Pericardial abnormal findings

ASD

Right atrium open looking into left atrium through ASD

Normal

© Frank Netter, MD Novartis®

fossa ovalis

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ASD----hemodynamicsASD----hemodynamics

RA LA

RA flow ↑ RV flow ↑ PBF↑

RA hypertrophydilatation

RV hypertrophydilatation

pulmonary hypertension

Right heart failure

methods

normal

abnormities

diseases Left → right shuntLeft → right shuntBut

depend on theP. Vscular resistance

Page 59: Pericardial abnormal findings

• Discontinuity in the atrial septum with systolic signal void consistent with L->R shunt on atrial level

• Right atrium is mildly dilated; RV, LV and LA size are normal

SCMRAuckland MRI

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ASDASD

Clinicmostly adult

SM on the 2th-3rd intercostal of the left sternal border

Change of hemodynamics

X-ray appearanceCardiomegaly , “mitral configuration”

RA & RV↑, RA↑ ↑ obviously

Pulmonary artery segment bulge , hilum angiectasia, hilum dance

pulmonary blood flow↑ ↑. PAH in later stage

LA do not enlarge, LV and aorta shrink

methods

normal

abnormities

diseases

4 type:Ostium primum , ostium secundumSinus venosus , coronary sinus

Fossa Ovalis defect80~90%

Atrial septal defect

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ASD

RA

RA

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ASDaorta shrink

RA & RV↑, RA↑ ↑ obviously

RA

RV

PA

Aorta

svc

Page 63: Pericardial abnormal findings

ASD

RA & RV↑, RA↑ ↑ obviously

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ASDASD

Enlargement of RA

methods

normal

abnormities

diseases

RA

RV

PA

Aorta

svc

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ASDASDmethods

normal

abnormities

diseases

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ASDASD

Preoperative Postoperative

methods

normal

abnormities

diseases

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ASDASD

Pulmonary hypertensionPulmonary hypertension

methods

normal

abnormities

diseases

RA

RV

PA

Aorta

svc

Page 68: Pericardial abnormal findings

ASD

Prominent pulmonary vessels

Prominent MPA

Normal left atrium

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Tetralogy of FallotTetralogy of FallotMost common CHD with hematoasthenia and cyanosis Including four anomalies :

Pulmonary stenosisVentricular septal defectAortic overridingHypertrophy of the RV

Radiologic findings

Cardiac apex displaced upward “coer en sabot”

PA segment concave Decreased vasculature R aortic arch in 25%

methods

normal

abnormities

diseases

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Fallot’s tetralogyFallot’s tetralogymethods

normal

abnormities

diseases

Page 71: Pericardial abnormal findings

Tetralogy of Fallot

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Tetralogy of Fallot

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Tetralogy of FallotTetralogy of Fallotmethods

normal

abnormities

diseases

Page 74: Pericardial abnormal findings

F4

Aortic overriding Pulmonary stenosis right→ left shunt RV hypertrophy

LA

RV

MR:41655

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F4

MR:41655

Page 76: Pericardial abnormal findings