Penyembuhan Luka

Stadium Penyembuhan Luka

dan Remodeling

1. Fase Inflamasi

- Hemostasis segera,platelet pembekuan darah

- Inflamasi hari ke-1, makrofag proses peradangan (tanda radang )

Time course of the appearance of different cells in the wound during healing. Macrophages and neutrophils are predominant during the inflammatory phase (peak at days 3 and 2, respectively). Lymphocytes appear later and peak at day 7. Fibroblasts are the predominant cells during the proliferative phase

hari 2-3. fibroblas -> angiogenesis, sel epitel -> deposit kolagen (tipe 3) ->

reepitelisasi

2. Fase Proliferasi

Wound matrix deposition over time. Fibronectin and type III collagen constitute the early matrix. Type I collagen accumulates later and corresponds to the increase in wound-breaking strength

3. Fase Maturasi

hari 7-21penyusunan serat kolagen remodeling