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1-4 July, Stresa, Italy

HEALTH AND WELLNESS TOURISM

LEADERS

The Grand Hotel des Iles Borromees Corso Umberto I, 67, Stresawww.borromees.it

Bus for tour to Milan

Funivia del Mottarone (Cable Car)Piazzale Lido, 8, 28838 Stresa Verbanowww.stresa-mottarone.it

Stresa Railway StationVia C Carducci, 28838 Stresa Verbano www.raildude.com/en/stresa-railway-station/stresa/station/13934/3220

Bus stop: Stazione Di ServizioVia Nettuno, 188 28838 Stresa Verbano-Cusio-Ossolawww.stresaturismo.it/trasporti.asp

Bus stop: Carabinieri Comando Stazione StresaVia Duchessa di Genova/Via Fratelli Omarini, 28838 Stresa Verbano-Cusio-Ossolawww.stresaturismo.it/trasporti.asp

Stresa Ferry Station / Imbarcadero (Boat Service)www.navigazionelaghi.it/eng

Bank Intesa Sanpaolo SpaPiazza Possi Dottor Felice, 128838 Stresa Verbano-Cusio-Ossolawww.intesasanpaolo.com/

Bank Di Legnano SpaVia Principessa Margherita, 45Stresa Verbano-Cusio-Ossolawww.gruppobpm.it/it-ist.html

Bank Popolare Di NovaraVia Principe Tomaso, 2628838 Stresa Verbano-Cusio-Ossola

Interactive map of Stresa: www.visitstresa.com/Stresa_Map.htm

VENUE

4 Programme

6 Participants

8 Speakers

10 Business Cards. Investment and Innovation Projects. Commercial Offers

52 International Contest ‘Stars of Health, Wellness and Tourism’

54 Decision on Rewarding

CONTENTS

CATALOGUE

LEADERS

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LEADERS

09:30–10:00 Registration

10:00–11:00 Plenary sessionWelcome speech:John Netting, Director General, Europe Business Assembly, UKKeynote speechesDr. Vincenzo Costigliola, President, European Medical Association, BelgiumDr. David George Vequist IV, Director/Founder of the Center for Medical Tourism/Travel Research, San Antonio, Texas, USA Medical Tourism- Evidence of a Continuum of Health Seeking BehaviorsDr. Iain Mcintosh, the Founder and Honorary Member of the British Association of Medical Tourism, UKMedical tourism and international travelling – main trends in 2014

11:00–12:15 Medical tourism: a fast growing industrySpeakers: tourist and travel agencies and associations, mayors of resort cities, medical travel professionals.Laszló Púczkó, Managing Director, Xellum Kft., Hungary Title: ‘Therapy or surgery? The evidence based treatment options in EU cross-border healthcare’Omer K. Isvan, President, Servotel Corporation, Turkey Mrs. Laura Natali, Europe Spa Association Vice President, Italy Maimunah Mohd Sharif, President, Municipal Council of Seberang Perai, Malaysia

12:15–13:15 SPA Industry and modern spa and wellness programmes as key element of healthcare travel. Jean-Guy de Gabriac, International Spa Consultant, TIP TOUCH CEO, Belgium Martha Wiedemann, Wellness Advisor, Badrutt’s Palace Hotel, Switzerland Erica D’Angelo, Owner and General Manager, Ti Sana Spa & Detox Retreat, ItalyRoger Allen, Managing Director, Thermarium Lesiure Management, Austria Title: ‘Planning & Executing a Spa Development – Understanding the Complexity’

13:15–14:00 Business lunch

14:00–16:00 Modern clinics (hospitals). Prominent players’ experienceDr. Claudia Mika, Managing Director, Temos International GmbH, Germany Prof. Dr. Oral B. Ospanov , President, Association of Endoscopic Surgery of KazakhstanDr. Matjaz Flezar, Director, University Clinic Golnik, Slovenia Paolo Rotelli, Vice-President, Gruppo Ospedaliero San Donato, Italy Dr. Nahi Yousif Yaseen, Director General, Iraqi Centre For Cancer And Medical Genetics Research, Iraq Dr. Reem Osman, SAUDI GERMAN HOSPITAL DUBAI, CEO, UAEDr. Soundarapandian Sivamurugan, Director, Soundarapandian Bone and Joint Hospital and Research Institute Private Limited, India Sopiko Ukleba, Coordinator, New Life Global Network, Georgia

2 JULY, WEDNESDAY

SUMMIT PROGRAMME

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LEADERSSUMMIT PROGRAMME

3 JULY, THURSDAY

Ida Ayu Oka Purnama Wati, SS, MM, Founder, Director of Marketing and Business Development, Bali Royal Hospital, Indonesia Natalia Zemna, President, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’’, Ukraine Dr. Mykola Nasikovskyy, President of Ukrainian Association of Manual Therapy

19:30–23:00 Socrates Award Ceremony ‘ЕВА. Best Enterprises. Achievements. 2014’Banquet, traditional musical entertainment and photo session

10:00–12:30 Workshop sessions SHD ItalySHD Italy offers his own know-how collaborating with the best professionals in the sector, studying and conducting planning solutions with the objective of satisfying the customers’ needs and ensuring the most efficient work place to the Medical team.The extensive experience gained in the past 30 years of activity in the HOSPITAL SECTOR and the availability of a Technical Staff with proved experience, allows at present to face up any issues concerning the hospital critical areas.Mr Lorenzini, Sales Director Fashionizer Couture UniformsFashionizer Couture Uniforms provides unique and iconic uniforms that define staff image as an integral part of your brand identity and marketing strategy. We are specialist uniform designers and suppliers of fashionable uniforms for Luxury Brands, 5 star Hotels, Resorts and Spas. Debbie Leon, Owner and Managing Director, UKMaster Class on Manual Therapy Treatment Methods of Dr. Mykola Nasikovskyy, President of Ukrainian Association of Manual Therapy

13.30-15.00 Presentations from medical tourism leaders and prize-winners of the international healthcare and travel arena competitionPeter Snucins, Polycorp Ltd Founder, President and CEO, CanadaDr. Jan Mitrev, Special Surgery Hospital Filip Vtori General Manager, MacedoniaDr. Robert Gajda, Medical Center Gajda-Med Director, PolandDr. Valentin Pavlov, EO DENT DENTAL CLINIC Manager, BulgariaAssist. Prof. Irfan Gunsel, Chairman of Board of Trustees Near East University Hospital, North CyprusViktor Zinchenko, Deputy CEO, Isida Hospital, IVF specialist, embryologist, Honored Doctor of Ukraine, Ukraine Olasoji R. Olagunji, Managing Director, Hurlag Technologies Limited, NigeriaMr. Andrej Reljic, Managing Director of Swiss Health, Switzerland

15:00 – 16:00 Summing upPresentation of certificates to winners of the international contest ‘Stars of Health, Wellness and Travel’

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LEADERS

Albania. Austria, Azerbaijan, Bangladesh, Belgium, Bulgaria, Canada, Georgia, Germany, Ghana, Hungary, India, Indonesia, Iraq, Italy, Jordan, Macedonia, Malaysia, Nigeria, North Cyprus, Philippines, Poland, Republic of Belarus,

Republic of Tajikistan, Republic of Uzbekistan, Romania, Russian Federation, Saudi Arabia, Slovenia, South Africa, Switzerland, Turkey, UAE, Ukraine, United Kingdom, USA, Vietnam

Dina Turakbayeva, Chief Medical Officer, 1st Perinatal Center, Republic of KazakhstanOral Ospanov, President, Association of Endoscopic Surgery of Kazakhstan (AESK), Republic of KazakhstanAbil Aghasiyev, President, Azerbaijan Republic ‘Kurort’ Joint-stock company, AzerbaijanMartha Wiedemann, Wellness Advisor, BADRUTT’s PALACE HOTEL, SwitzerlandAbdulmuttaleb Abdul Ghani Naser Al - Jawhar, Dean, Baghdad College of Pharmacy, IraqQassim Jaleel Ibrahim Ibrahim, Professor, Baghdad College of Pharmacy, IraqIda Ayu Oka Purnama Wati, Founder, Bali Royal Hospital, IndonesiaI Gede Wiryana Patra Jaya, Managing Director, Bali Royal Hospital, IndonesiaIain B. McIntosh, Founder member, and Honorary Fellow, British Global and Travel Health Association, United KingdomDavid G. Vequist, Founder/Director, Center for Medical Tourism Research, USAMunsur Ahamed, Managing Director, Central Pharmaceuticals Ltd., BangladeshBabatunde Olaniya, Head, Strategy & Business Development, Chemstar Paints Ind. (Nig.) Ltd., NigeriaAdedayo Olusesan Paseda, Representative, Chemstar Paints Ind. (Nig.) Ltd., NigeriaLe Ngoc Hoa, General Director, Civil Engineering Construction Corporation No.4, VietnamVan Chin Tran, Deputy General Director, Civil Engineering Construction Corporation No.4, VietnamVan Hung Nguyen, Chief of Office, Civil Engineering Construction Corporation No.4, VietnamKhac Tuan Ngo, Deputy General Director, Civil Engineering Construction Corporation No.4, VietnamNgoc Vinh Le, Representative, Civil Engineering Construction Corporation No.4, VietnamAnton Savvov, President, East Ukrainian Academy of Business, UkraineTetiana Grebeniuk, Vice-President, East Ukrainian Academy of Business, UkraineDorina Nako, Export Manager, ELKA SA, AlbaniaEli Jorgji, General Manager, ELKA SA, AlbaniaValentin Pavlov, Manager, EO DENT DENTAL CLINIC, BulgariaElica Yoncheva, Dentist, EO DENT DENTAL CLINIC, BulgariaKalin Stoimenov, Dentist, EO DENT DENTAL CLINIC, BulgariaNetting John, Director General, Europe Business Assembly (EBA), United KingdomIvan Savvov, Director of International Relations, Europe Business Assembly (EBA), United KingdomVincenzo Costigliola, President, Europe Medical Association, BelgiumLaura Natali, Vice President, Europe Spa Association, ItalyDebbie Leon, Director, Fashionizer Couture Uniforms, United KingdomIgor Rachitskiy, Director General, GAZOSILIСAT, Private Enterprise, Republic of BelarusLudmila Rachitskaya, Representative, GAZOSILIСAT, Private Enterprise, Republic of BelarusOksana Rachitskaya, Representative, GAZOSILIСAT, Private Enterprise, Republic of BelarusGeorge Sipa-Adjah Yankey, CEO, Ghana National Gas Company, GhanaAlfred Ogbamey, Comunication Manager, Ghana National Gas Company, GhanaNataliya Gryshyna, Director, Group of companies ANTRA, UkraineMariya Gryshyna, Travel Manager, Group of companies ANTRA, UkrainePaolo Rotelli, Vice-President, Gruppo San Donato - University and Research Hospitals, ItalyOlasoji R. Olagunji, Managing Director, Hurlag Technologies Limited, NigeriaMarko Licon, Owner and CEO, Insol d.o.o, SloveniaAli Al-Adeeb, Iraqi Minister of Higher Education and Scientific Research, IraqNahi Yousif Yaseen, Director General, Iraqi Centre For Cancer And Medical Genetics Research, IraqViktor Zinchenko, Deputy CEO, Isida-IVF, UkraineLarysa Melnyk, Head of International Department, Isida-IVF, UkraineAli Wazaney, Board Member, Jordan Insurance Federation, JordanImad Jeries, Board Member, Jordan Insurance Federation, JordanMaher Al-Hussein, Federation Director, Jordan Insurance Federation, JordanNatalya Akhmadulina, Director, Kyzylkum Tyulpan, Republic of UzbekistanVladimir Akhmadulin, Specialist of Marketing, Kyzylkum Tyulpan, Republic of UzbekistanBernard Faustino Dy, City Mayor, Local Government Unit Cauayan City Isabela, PhilippinesMiklos Hegyi, CEO, Maxidor, South AfricaRobert Gajda, Director, Medical Center Gajda-Med, PolandBeata Gajda Robert, Assistant, Medical Center Gajda-Med, Poland

SUMMIT PARTICIPANTS

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LEADERSSUMMIT PARTICIPANTS

Mariya Troychak, Director, Medical centre ‘Barvinok’, UkraineSailaukhan Auyelbayeva, Director, Medical-wellness center ’Sailaukhan’, Republic of KazakhstanGulnar Telenbayeva, Interpreteur, Medical-wellness center ‘Sailaukhan’, Republic of KazakhstanShermat Ashirbayev, Editor, Medical-wellness center ‘Sailaukhan’, Republic of KazakhstanNazgul Yefimenko, Medical-wellness center ‘Sailaukhan’, Republic of KazakhstanGafur Jafarov, Managing Director, Medistyle Hospital (Renessans-S), AzerbaijanMaimunah Mohd Sharif, President, Municipal Council of Seberang Perai, MalaysiaAmira Adli Lai, Representative, Municipal Council of Seberang Perai, MalaysiaIsmail Said, President, Municipal Council of Sungai Petani, Kedah, MalaysiaSuhairi Mustaffa, Architect, Municipal Council of Sungai Petani, Kedah, MalaysiaKok Leong Cheng, CEO, Nanopac (M) Sdn Bhd, MalaysiaChin Woi Ho, Manager, Business Development & Technical, Nanopac (M) Sdn Bhd, MalaysiaIrfan Gunsel, Chairman of Board of Trustees, Near East University Hospital, North CyprusGorkem Bulunc, Representative, Near East University Hospital, North CyprusMariam Kukunashvili, Founder, New Life Global Network, GeorgiaSopiko Ukleba, Founder, New Life Global Network, GeorgiaAhmed Shamiyah, Medical Director, Noble Smile Dental Care, Saudi ArabiaPeter Snucins, Founder, President and CEO, Polycorp Ltd, CanadaAmanzhol Adayev, Chief Doctor, Private clinic SHAPAGAT, Republic of KazakhstanIda Bagus Indrajaya, Director, PT Putra Husada Jaya, IndonesiaNatalia Zemna, Founder, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineRostislav Zhelyaskov, Director, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineZarina Zhelyaskova, Specialist-Consultant, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineYuriy Naboka, Specialist-Consultant, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineAxiniya Zheliaskova, Specialist-Consultant, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineVadim Shlapak, Specialist-Consultant, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineSvetlana Mukanova, Physician Superintendent, Regional public organization of disabled people ‘Human Health’, Russian FederationReem Osman, CEO, Saudi German Hospital Dubai, UAESobhi Abdul Jalil Batterjee, President, Saudi German Hospital Dubai, UAEOmer K. Isvan, President, Servotel Corporation, TurkeySivamurugan Soundarapandian, Director, Soundarapandian Bone and Joint Hospital and Resarch Institute Private Limited, IndiaJan Mitrev, General Manager, Special Surgery Hospital Filip Vtori, MacedoniaFlorika Mitrev, Representative, Special Surgery Hospital Filip Vtori, MacedoniaEmmanuel Ajayi, CEO, Swiss Biostadt Limited, NigeriaAndrej Reljic, Managing Director, Swiss Health, SwitzerlandMuazzam Ansorov, Rector, Tajik Pedagogic Institute in the city of Penjikent, Republic of TajikistanRuziboy Mahmudov, Representative, Tajik Pedagogic Institute in the city of Penjikent, Republic of TajikistanClaudia Mika, Managing Director, Temos International GmbH, GermanyGalina Karimova, Chief, The International Medical Center – MMC ODA, Russian FederationMaximilian Kravchik, Head of the Department of Rehabilitation, The International Medical Center – MMC ODA, Russian FederationRoger Allen, Managing Director Thermarium Leisure Management, THERMARIUM Bäder-Bau GmbH, AustriaErica D’Angelo, Owner and General Manager, Ti Sana Spa & Detox Retreat, ItalyJean-Guy de Gabriac, CEO, TIP TOUCH, BelgiumMykola Nasikovskyy, President, Ukrainian Association of Manual Therapy, UkraineMohammed Nasr Abdeen, CEO, Union National Bank, UAEMohammad Ali, SVP & head of HR & OD, Union National Bank, UAEMatjaz Flezar, Director, University Clinic Golnik, SloveniaAzamfirei Leonard, Rector, University of Medicine and Pharmacy Tirgu Mures, RomaniaMrs. Gabriela Azamfirei, Representtaive, University of Medicine and Pharmacy Tirgu Mures, RomaniaKazhimkan Massimov, Director General, Wellness Center of Massimov LLP, Republic of KazakhstanEleonora Massimova, Representative, Wellness Center of Massimov LLP, Republic of KazakhstanKalelkhan Imanmadi, Representative, Wellness Center of Massimov LLP, Republic of KazakhstanZhansaya Imanmadiyeva, Representative, Wellness Center of Massimov LLP, Republic of KazakhstanAizhan Baibossynova, Wellness Center of Massimov LLP, Republic of KazakhstanLaszló Púczkó, Managing Director, Xellum Kft., HungaryMargaryta Bagirova, Folk Healer, UkraineElvira Cherepanova, Director General of management company LLC Sanatorium Complex ‘Mashuk Aqua-Therm”, Russian Federation, Caucasian Mineral Waters

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LEADERS

Dr. Vincenzo CostigliolaPresident of the European Medical Association, Belgium Dr. Costigliola graduated in Medicine from the University of Naples in 1972 and in Anaesthesiology and Intensive Care from the University of Pisa in 1978. He also attended post-graduate studies in Rheumatology, Dermatology, Proctology, Oncology, Surgery, Drugs Abuse, Emergency Treatment, Disaster Action, Hospital Organization, Medical Teaching Methodology and Computer and Audio-Visual Training for the Medical Profession. His professional experience ranges from senior military positions as Chief of Medical Services in the Italian Navy for a number of years, responsibility of the outpatients clinic of the Shape Hospital in Belgium and family practice in Italy and Belgium. Membership of professional bodies. President of E.M.A. (European Medical Association). President of E.D.A. (European Depression Association). Member of Editorial Advisory Board of ‘Psychiatry in primary care journal’. Extensive experience in informatics’ health programmes. Teaching experiences. Nationals and internationals conferences as a speaker. Publishing experiences. Member of the Steering Committee Health First Europe. Stakeholder Nutrition & Health 2020. Additional Competences and Duties. Dr. Costigliola is fluent†in Italian, French, English and Spanish. Good experience in clinical trials. Extensive experience in European health care field. Main contractor and participant in many EU projects of Directorate 22 and Directorate 5. Selected as expert-evaluator in the 5th Framework programme

David George Vequist IV, Ph.D.Director/Founder of the Center for Medical Tourism/Travel Research, San Antonio, Texas, USA‘Medical Tourism- Evidence of a Continuum of Health Seeking Behaviors’David G. Vequist IV, Ph.D. is the founder and Director of the Center for Medical Tourism Research (www.medicaltourismresearch.org) - the very first academic center devoted to medical tourism research in the world. He is also a Tenured Associate Professor of Management in the H-E-B School of Business & Administration at the University of Incarnate Word in San Antonio, Texas, USA. So far, he has presented on three continents about the business of medical tourism and has also produced several articles, papers, and is currently writing a book on the economic issues and impact of medical tourism. He is also a consultant, author, speaker, and futurist with a focus on topics such as healthcare, technology, and training. David Vequist`s main research topic are: Medical Tourism (includes topics such as Health, Wellness, Dental, Reproductive, Retirement, and Death Tourism);Training Methods and Technologies; Management of Technology; Business Strategy; Project Management; Competency Modeling; CRM/Data Warehousing/Mining; Knowledge Management; Organization Behavior/Development/ Effectiveness; Quality/Process Improvement; Human Resources and HRIS systems

Dr. Iain B. McIntoshFounder member, and Honorary Fellow of the British Global and Travel Health Association, UK‘Medical tourism and international travelling – main trends in 2014’BA (Hons), MB ChB, DGMRCP, FTM RCPS (Glasgow), FBGTHA, FMDHS, Founder member and Honorary Fellow of the British Global and Travel Health Association, Council Member and Executive Officer since its inception and is its Immediate Past President.Many years as primary care physician and hospital doctor (geriatrics) and latterly air repatriation physician. Author of 7 books on travel related medicine and many scientific research articles. Editor in Chief British Global and Travel Health Association Journal and Travelwise. Lecturer on travel medicine and elderly care at Stirling and Glasgow Universities. Extensive world travel and medical work especially in developing countries.

Laszló PúczkóManaging Director, Xellum Kft., Hungary‘Therapy or surgery? The evidence based treatment options in EU cross-border healthcare’Laszlo Puczko is an economist (MSc), art & design manager (MA) and PhD (in tourism). Laszlo has been involved in wellness, thermal and medical tourism for over 15 years. He is the co-author of the first global overview of Health and Wellness Tourism. He is the Managing director of Xellum Ltd, a consulting and research firm. Global medical tourism is characterized by invasive treatments from plastic surgery, to dental interventions. Many countries, however, have assets and traditions that can, in many cases prevent or postpone invasive treatments. This is a great, but so far mainly missed opportunity for many destinations and service providers. Laszlo has been involved in wellness, thermal and medical tourism for over 15 years working for private companies and public sector organizations. Among others he advised the Hungarian National Tourist Office on health tourism marketing, the Ministry of Regional Development on the Tourism-specific Quality of Life Index preparation, prepared a Regional Health Tourism Development Strategy for Southern-Transdanubia, and now is advising the Hotel Association of Hungary on the service criteria for wellness and medical hotels. He has also worked for many private developers. His expertise was used from conceptualization to feasibility assessment of wellness tourism projects. In his latest project he is involved in the Global Spa Summit’s initiative on wellness tourism and spas. He was Board Member of Travel & Tourism Research Association Europe Chapter (2008-2010), and has been the President of Association of Tourism Consultants (Hungary) since 2006, Senior Professor at Budapest Corvinus University, and guest lecturer in the first European MA programme in Wellness and Spa Service Design and Management (Estonia).

Omer K. IsvanPresident, Servotel Corporation, TurkeyCelebrating its 28th year of growth into a global Hotel & Resort consulting boutique, Servotel Corporation is now widely recognized as the leading advisor in the investment and development of hotels, resorts, and integrated mixed-use developments worldwide. Backed up with industry-leading specialists based in London and Istanbul, Isvan’s experience spans over 43 countries and numerous projects advising investors in every steep from green-field stage through to asset management of hotels & resorts, including hotel and spa operator selection and negotiations with most leading brands. Isvan’s unique approach and vision for development advisory led to a fully integrated multi-discipline structure including specialists in concept and creative elements, legal, economic, financial, market research & marketing, design & engineering to complement and cohere the investor, its architects, designers and operators throughout the development and pre-opening process. A graduate of University of Surrey, England, Isvan is a member of Institute of Hospitality; Institute of Directors and British Institute of Management. Isvan is also reported to have introduced the term ‘boutique hotel’ into the industry and is one of few industry leaders to make the cover of Business Week magazine. Alongside his career, Isvan contributes to the industry by delivering keynote lectures in hospitality development at conferences and leading universities and corporate MBA’s globally. Mrs. Laura NataliEurope Spa Association Vice President, ItalyLaura Natali has a bachelor diploma in classical studies. She graduated at Pisa University, as doctor in engineering. Main roles:Managing Director at Terme della Versilia - Undulna company. Vice president of Europe Spa Association. Moral auditor of Federterme in Rome. Member of the board of Confindustria Small Industry Division in Rome Managing director of Versilia N G, a company running the hotel annexed to Terme della Versilia. Expert in a certification company for the construction sector in Milan Member of the board of Henraux spa, a prominent stone industry company Managing director of Immobiliare Toscana

SUMMIT SPEAKERS

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LEADERS

Jean-Guy de GabriacInternational Spa Consultant, TIP TOUCH CEO, BelgiumFounder of a massage institute & school near the Champs-Elysées in Paris (2001-2004), Jean-Guy de Gabriac then developped TIP TOUCH in 2004 as a leading Spa training & consultancy company. He speaks regularly at Spa conventions and Beauty trade-shows: in France (Beyond Beauty, Mondial Spa & Beauté, Paris HOTel SPA); and abroad (Bali, Budapest, Istanbul, Lisboa, London, Milan, Monaco, Moscow, Prag, Warsaw…); He was of of the speakers of the Ecole Hôtelière de Lausanne (Switzerland) in 2010-2011 for 2 workshops in the Spa Management certification program. Active member of: the Commission of Global Spa & Wellness Summit on the education of Spa Managers; I-SPA (USA); LABEL SPAS DE FRANCE; AFNOR (joined the expert committee in 2011 to co-write the French norm for Spas); and is the 1st French member of the Green Spa Network to promote sustainability in spas. TOP Santé & Psychologies.com (the n°1 French portal on wellbeing) often quote him as massage Expert in a series of articles on the benefits of massages, and has been appointed as one of the Judges for the World Spa Awards in 2012, 2013 and 2014.

Martha WiedemannWellness Advisor, Badrutt’s Palace Hotel, SwitzerlandMs. Martha Wiedemann is the international Ayurvedic and wellness expert.She has been engaged in the Health and Beauty industry since early 1980’s. Martha started her business by opening first own Health and Beauty Centre within a 5 Star Hotel in 1987. After studying Ayurveda at the European Institute of Vedic Studies, Ms. Wiedemann has a successful experience of introducing own Ayurvedic approaches at the spa and wellness centres in the leading Swiss hotels. Ms. Martha Wiedemann developed own 7 days detox program according to the Ayurvedic system of health. After having worked in various spas and wellness centres, Martha was able to identify some of the limitations of delivering wellness within certain architectural constructions. Together with various experts in the design project of Palace Wellness at the Badrutt’s Palace Hotel, she was even able to include the subtle effects of ‘Vastu Veda’ (the science of construction according to Ayurveda) into the physical design elements in terms of energy flow within architecture bringing harmony to the building and space. Ms. Martha Wiedemann continues to run training programs for the Wellness team, upgrade and expand on the Palace Wellness product. Her on-going research on wellness practices aid me in creating new therapies, treatments and facilities to meet the growing demands of clients of the Wellness industry. She cooperates with Ecole hôtelière de Lausanne on creating Spa concepts. Roger AllenManaging Director, Thermarium Lesiure Management, AustriaPlanning & Executing a Spa Development – Understanding the Complexity’Roger is a twenty year veteran of the international hotel and leisure sector where he is specialized in the asset management, development & operations of leisure establishments, incl. hotel/cruise ship spa & wellness facilities, resorts, health clubs and medical spas with project experience in Europe, US, CIS, Asia and the Middle East. Roger has held senior management positions in multinational companies in Europe, Asia and the US. He is a former partner at Horwath HTL Consulting Hungary and has extensive experience of developing, operating, owning and selling leisure establishments. He works on multiple levels of project development and operations with particular focus on protecting investor interests and managing the complexity of project planning and delivery. With experience of working with financial institutions and raising capital for leisure projects Roger takes a very entrepreneurial approach to leisure development, which is a very focused and aggressive perspective of how a leisure business can and ‘should’ deliver a ROI without compromising the guest experience. As Managing Director of a global company that provides a comprehensive range of leisure solutions to some of the most recognised international hospitality brands and iconic properties Roger is at the forefront of the industry developments and the investment trends behind them.

Dr. Claudia MikaManaging Director, Temos International GmbH, GermanyDr. Claudia Mika is the Managing Director of Temos International GmbH, a spin-off of the German Aerospace Center, DLR, a German governmental research organization. Since 2004 she has been working on the Temos Certification Systems, assessing hospitals, rehabilitation centers and dental clinics worldwide according to the Temos quality criteria for international patients, developed together with leading travel health insurances and assistance companies. Due to the Temos Quality Certifications of internationally oriented medical institutions and supported by Dr. Mika’s consultancy work for the implementation of International Patients’ Departments in medical facilities all over the world she is very well grounded in medical tourisms topics. She has been working with more than 100 hospitals and medical facilities worldwide from Brazil to the Philippines. Dr. Mika is a certified auditor for ISO 9001. Her expertise in quality management and international health tourism is in great demand, not only among hospital managers and practitioners around the globe. Dr. Mika has been regularly invited to international Medical Tourism Conferences and advises different associations and governmental institutions regarding medical tourism issues. She recently finished the guideline ‘International Patients Department Processes’ for the Turkish Ministry of Health. In 2002, Dr. Mika received the ‘Young Researcher Award’ of the European Space Agency. She held guest lectureships at PUCRS University in Porto Alegre, Brazil, and at the University Hospital in Aachen, Germany. Since 2007 she has also supervised several tele-education courses that brought doctors and medical students from various international universities together via videoconference. In 2011, Dr. Mika received the ‘High Potential Company Award 2011’, funded by the European Union. In 2013 Dr. Mika was appointed to be one of the judges for the International Medical Travel Awards, an independent and objective set of awards for the medical travel and tourism industry. Since January 2014 she is the Vice Chairwoman of the Diplomatic Council Healthcare Forum.

Dr. Matjaz FlezarDirector, University Clinic Golnik, SloveniaToday the University Clinic Golnik is a clinical, pedagogic and research institution where patients with pulmonary, allergic and other internal diseases from around Slovenia are treated. It is a fully equipped clinic providing tertiary health care for pulmonary and allergic diseases for Slovenia. It introduces new fundamental and clinical developments and is a teaching place for under- and postgraduate medical students of The Faculty of Medicine of the Ljubljana University Dr. Matjaz Flezar holds research work in the fields that are of importance to the clinic and constantly invest in technical development.

SUMMIT SPEAKERS

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LEADERSBUSINESS CARDS. INVESTMENT AND INNOVATION PROJECTS. COMMERCIAL OFFERS

AZERBAIJAN TRADE UNIONS CONFEDERATION ‘KURORT’ JSC Aghasiyev Abil, President Nizami park, Nobel street 57/2, AZ1025, Baku sity, Azerbaijan e-mail: [email protected] www.ahik.org

Azerbaijan is a republic possessing greater natural treatment factors, unique recreation and resort resources. Azerbaijan occupies one of the leading places in the word according to its various natural resources. Climate conditions of Azerbaijan are completely varied: from subtropical to severe continental.There was found out a number of high-quality therapeutic mud sources and unique therapeutic Naftalan oil up to a thousand in the Republic. The nature generously gifted to Azerbaijan the waters such as isti su, tursh su, badamli, sirab, surakhani sulphuric water, Lankaran and Davachi mineral waters. Consequently there were created great opportunities in order to use balneological, mud and climatic therapeutic factors in the sanatoriums established in Azerbaijan.In 1922, there was established ‘Kurort’ Join-Stock Company on the base of Council of Republic of Azerbaijan for Management of Resorts of Trade Unions. Presently, the sanatoriums such as ‘Bilgah’ for treatment of cardiologic diseases, ‘Absheron’- gastrointestinal diseases, ‘Garangush’- kidney diseases,’Gunashli’-nervous system diseases, ‘Shikh’-joint diseases and ‘Naftalan’ Resort Union for treatment of various diseases, provide specialized sanatorium-resort services for the people of the republic.There was adopted ‘Azerbaijani resorts’ State program (2007-2017) and the law of the Republic of Azerbaijan ‘On natural treatment resources, treatment-improvement places and resorts in 2007. This law and State program took effect as per executive order signed by Mr.I.Aliyev, the President of the Republic of Azerbaijan.In accordance with State Program of ‘Azerbaijani Resorts’, there are carried out intensive improvement, repair and reconstruction works in health -care centers of ‘Kurort’ Join-Stock Company where ten thousands of people are treated, in addition to which their technical base is being updated, ways are searched for modernization of diagnostics and treatment of patients.

ANTRA GC ANTRA-GROUP ltd. Valery Gryshyn , Chairman of the Supervisory Board Nataliya Gryshyna, Director Uspenskaya Street, 101, Odessa, 65045, Ukraine phone: +38 048 777-01-66, +38 048 717-86-26 fax: +38 048 711-72-73 e-mail: [email protected] www.antra.ua, www.antra-tour.com

Antra company was established in 1996. The main businesses are: - information technologies, service in e-document management via use of digital signature - organization of seminars, webinars and trainings in the accounting, management and marketing areas.- organization of educational tours with the aim to study foreign languages abroad (Malta, Ireland, Spain, Australia) - The tour operator’s activity both in hosting guests in Ukraine and sending the applicants abroad - call center services The ’Antra’ company is opened for dialogue and new ideas.

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BALI ROYAL HOSPITAL Ida Ayu Oka Purnama Wati, Founder and Director of Marketing & Business Development Jalan Tantular 6, Denpasar, 80235 – Bali, Indonesia phone: +62 361 247499 fax: +62 361 226051 mobile: +628123942828 e-mail: [email protected] www.baliroyalhospital.co.id Bali Royal Hospital (BROS) opened its doors on 17th July 2010 to provide comprehensive medical services to local patients and tourists in the island of Bali and across East Indonesia. Located in Jalan Tantular 6, in civic center Renon – Denpasar, it is very accessible for all patients. BROS has 61 rooms and total of 112 beds which falls under 8 room categories namely Royal Class, Royal Princes, Royal Prince, Royal Queen A,B,C, Royal King and Royal Majesty. It also has Intensive rooms such as HCU/ICU, NCCU, NICU and PICU. It is equipped with modern and sophisticated supporting diagnostic equipment such as CT-Scan multi slices, USG 4 Dimension, Mammography, Laboratory, Radiology, Radio Frequency Pulse, C-Arm, etc. BROS is supported by competence and professional human resources and physician to ensure the best practices across its four centers of excellence—in vitro fertilization, endoscopy, neuroscience and cosmetic surgery— as well as homecare and general medical practice.CENTRE OF EXCELLENCE- IVF (In Vitro Fertilization)It is a breakthrough for infertile couples specially designed by a team of Obstetric and Gynecologist focusing on assisting infertile couples with the latest technology (Assisted Reproductive Technology) or well known as In-Vitro Fertilization (IVF).It is supported by a great team consist of an Obstetric and Gynecologist, Andrologist, Embryologist, Urologist, Anesthesiologist and a Psychologist that will help the couple with various procedures such as Intra Uterine Insemination (IUI), Conventional In-Vitro Fertilization, Intra Cytoplasma Sperm Injection, Percutaneous Epidyma Sperm Aspiration and Testical Sperm Extraction. - Minimum Invasive Surgery (Endoscopy)Endoscopy is one of the diagnostic tools with minimum surgery to evaluate the internal organ by inserting a telescope into the intra abdominal cavity. This will not only enable us to see the internal organ diagnostically, but also to take an operative procedure , i.e. biopsy.At the moment Bali Royal Hospital provides endoscopy for Obstetric and Gynecology, Urology and Digestive. Soon, we will enhance the services to Gastro endoscopy, Bronchoscopy and Colonoscopy.- Cosmetic SurgeryPlastic surgery is a medical specialty concerned with the correction or restoration of form and function. Though cosmetic or aesthetic surgery is the best-known kind of plastic surgery, most plastic surgery is not cosmetic; plastic surgery includes many types of reconstructive surgery, hand surgery, microsurgery, and the treatment of burns. BROS is working on reconstructive surgery such as Labiaplasty ; working with ‘YAYASAN SENYUM FOUNDATION’ to help unfortunate children with labioplasty cases. We also do Rhinoplasty, Abdominoplasty, Breast Augementation and Liposuction. We are onto ‘cosmetic surgery’ such as mammoplasty, blepharoplasty, Face lift, Otoplasty, chin augmentation by working together with Medical Agents overseas.- Neuro Science Centre An intergrated services – a team of Neurologist, Neuro Surgeon, Radiologist, Neuro Anestesiologist, physiotherapist to cater all neuro and neuro surgery cases. At Bali Royal Hospital, we have successfully done some surgery for Brain tumor, hydrocephalus, head injuries, cervical spondylosis, Aneurysma Cerebri, Stroke and other neurological disorder.INTERNATIONAL SERVICESBROS has also launched RIPAC (Royal International Patient Assistance Centre) on 27th July 2012. It is specially designed to assist FOREIGN and Expatriate patients , especially on their medical treatment, visa, immigration, insurance and medical evacuation if required. With the 24 hours ALARM Centre , we will be able to assist any international patients, besides we provide translators for almost 8 nationalities.

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LOCAL GOVERNMENT UNIT CAUAYAN CITY ISABELA Hon. Bernard Faustino M. Dy, Mayor 107 Rizal Avenue Cauayan City, Isabela, 003305, Philippines phone: +0917 766 8038, +0918-922-1952 e-mail: [email protected] www.cityofcauayan.gov.ph

CAUAYAN CITY: THE IDEAL CITY OF THE NORTHIt is the thrust of Cauayan City to make it the ideal place where everything you are looking for can possibly be found; the center for business, education, career opportunities, leisure and recreation; the best place for building a family life, a God-centered community of empowered citizenry with rich culture, living in a healthy, clean and peaceful environment, under the leadership of an honest, innovative, and citizen-oriented government. Political and Social Stability. The Cauayan City Hall, grandly standing at the center is the representation of a unified, transparent, accountable, steadfast, and compassionate administration that governs Cauayan City. The City Government is in strong cooperation with the officials of the Liga ng mga Barangay, the Barangay Councilors League, Federation of Student Government Council, city departments and other organizations in programs with respect to nutrition, education, security, tourism, social welfare, local governance, environment and sanitary management, and economic development. Cauayan City is the first city in the Northern Philippines to adopt the Public-Private Partnership Code to involve the private sector in the implementation of projects and social services. The City Mayor, Hon. Bernard Faustino M. Dy, with the support of our City Vice-Mayor, Hon. Bartolome Mallillin, together with the members of the city council, commits himself with great enthusiasm to take into account every concern of every sector, in the crafting of policies and decision-making processes, thus, serving as the medium in building the city a home to a progressive and vibrant economy with empowered citizenry.Economic Environment. At present, there are a total of 2,515 existing business establishments in the city; 77 banks and financial institutions, 25 hotels, 33 restaurants, 26 amusement, 10 agricultural retails, 157 wholesalers and manufacturers, to name a few. SM City Cauayan and Robinson’s Place, some of the multi-national corporations in the Philippines, have expanded their investment in the city. The Cauayan City Public Market will be upgraded as Greenway Healthcare and Social Guaranties. We actively participate in health programs and activities such as feeding and nutrition programs, risk management and first-aid, national disability prevention and rehabilitation, Elderly Week, Alay Lakad, and the Senior Citizens’ Affair, as well as the conduct of free medical, dental, and optical missions at least thrice a month, to truly promote a healthy citizenry in Cauayan City. We have a total of 7 hospitals, 37 medical clinics, 15 dental clinics, 4 dermatology clinics, 4 EENT clinics, 3 orthopedic clinics, and 8 optical clinics, with complete and modern medical facilities enough to provide medical care. We are the only city which has a Mobile Clinic which travels even in the barrios to provide medical services. Recreation and Entertainment. Cauayan City is indeed a destination in Region 2 with tourism potentials; the Our Lady of the Pillar Church, a Hispanic Church beautifully designed with the ruins of its grandeur past; the Mushroom Center where fresh and processed mushrooms can be found; Gulayan ng Bayan, plantation of fresh and organic vegetables. Coffee shops and resto-bars are among the trending businesses. Cauayan City has its own high-end hotels for the accommodation of visitors such as the Isabela Hotel, JAPI Traveller’s Hotel, Hotel Andrea and Restaurant, Amity Hotel, and Queen Jennifer Hotel. One of the newest attractions in the city is the Cagayan River Cruise, the first-ever initiated activity in Cagayan Valley, the longest river in the Philippines. We are initiating efforts to create the Eco-Tourism Park. All these efforts are aimed to make Cauayan City the Ideal City of the North.

CHEMSTAR PAINTS INDUSTRY (NIG.) LIMITED Emmanuel Aderemi Awode, Chief Executive Officer Km 32, Caaso Bus Stop, Lagos-Abeokuta Expressway, Lagos, Nigeria phone: 234 01 7744066 e-mail: [email protected] www.chemstargroup.com Chemstar Paints Ind. (Nig.) Ltd is a home of great quality paint products. With a wide variety of colors which comes in different categories, you will always find a product that meets your immediate need. The company was incorporated in 1995 and immediately commenced manufacturing and marketing of good quality paints & allied products. Affordable prices endeared the products to users of paints products. Our customers are at the core of our business and we make it ease for us to receive and service their needs. Documentation include with explanations for most of the options. Our products are widely recognised both within and outside the country. We provide you with a wide range of colours to choose from. Our multi-million naira office and factory equip with the best human power ensures that our production line never stops. Products are tested in our well-equipped Quality Control Laboratory.

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CENTRAL PHARMACEUTICALS LTD. Munsur Ahamed, Managing Director Aziz Bhaban (8th Floor), 93 Motijheel C/A, Dhaka 1000, Bangladesh phone: +88-02-7119404 fax: +88-02-9565992 e-mail: [email protected] www.centralphl.com Central Pharmaceuticals Ltd. was incorporated in 13 November, 1980 as a ‘Private’ Company limited by shares and registered with the Registrar of Joint Stock Companies & Firms of Bangladesh under the Companies Act, 1913 vide Registration No. C-8514(353). On 20 December, 2010 the Company registered itself as a Public Limited Company under the Companies, Act 1994. The Company received consent for raising capital through IPO from Bangladesh Securities & Exchange Commission on 18 April, 2013. On completion of IPO compliance, the Company is listed with both Dhaka Stock Exchange Limited (DSE) and Chittagong Stock Exchange Limited (CSE) at 22 July, 2013 and 15 July, 2013 respectively and trading of the share of the Company has been started from 14 August, 2013.It may be mentioned that the Company had floated its 14,000,000 nos of shares amounting to Tk.10 per share to raise Tk.14.00 crore from general public through Initial Public Offering (IPO) which was oversubscribed (45 Times).Central Pharmaceuticals Ltd. (CPL) is producing and marketing finished formulation products for general Peoples, Hospitals, Clinic, Govt. Organizations, NGO’s, Corporations & other Non-govt. Organizations. 16 Moderate Portfolio consisting of 71 medicines approved by the Drug Administration of Bangladesh that prevent, treat and cure diseases across a significant range of therapeutic areas as approved by drug Administration. Central Pharma’s portfolio encompasses various therapeutic categories, including Gastrointestinal, Anti-infective, Vitamins & Minerals, Allergy Cough and Cold, Analgesic and Musculoskeletal, Dermatological, Anti Diabetic (New product coming very soon), Oral Rehydration Salt etcWe are committed to provide sustainable solutions to the health care challenges. Our business is successfully operated and our services towards nation are smoothly run by the efficient field forces. We have already introduced some new products and some of them are to be introduced soon.Thus our sales volume is in increasing rate and our Company growth is always in progress. In continuation of our success and achievement, we are in implementation of BMRE (Balancing Modernization Replacement & Expansion). We always stick to our belief and focused ideas and activities to make our dream true. At the same time, we are equally focused on low production cost and high quality products. All of our initiatives are directed towards the value creation for our shareholders and customers.

LLP MEDICAL CENTER DARUS AND LLP MEDICAL CENTER DARUS PLUS Zhanna Azimova, Founder 18/2, Imanov Str, Astana, 010000, Republic of Kazakhstan 96, Baytursinov Str, Almaty, 050000, Republic of Kazakhstan phone/fax: +7 717 253 70 07, +7 717 253 73 33 e-mail: [email protected] www.darus.kz Zhanna Azimova is founder of clinics of laser cosmetology and plastic surgery Darus and Darus +. She and her experts make people younger, prettier and therefore happier. Zhanna Azimova graduated in Almaty, Kazakhstan, ending Almaty State Medical Institute, specializing in endocrinology. For 12 years she worked for specialization in a city hospital № 7. In 2002, she opened in Astana, capital of Kazakhstan, clinic of laser cosmetology and plastic surgery Darus.First five years of work went on to bring the clinic to a decent European level, to purchase German lasers of Asclepion company and to train specialists in Germany. In December 2008, Zhanna Azimova opened Darus + clinic in Almaty. Today clinics of laser cosmetology and plastic surgery Darus and Darus + - is synonymous with reliability, comfort, safety and high quality services. Each year, specialists of clinics open to their customers new capabilities and procedures.In 2012, Zhanna Azimova opened Joint Antiaging Center Kazakhstan-Netherlands. Priority of work of Antiaging center is to recognize early symptoms of aging and reorient the patient to the correct lifestyle and nutrition to slow the biological aging process. All these years Zhanna Azimova worked in the field of aesthetic medicine and has mastered cosmetology specification, but she did not leave a specialization in endocrinology. In 2012 she received the European Diploma WOSAAM, World association of anti-aging medicine, the first category, of Medical Education Consortium USA. And now she is practicing as an expert in anti-aging. Clinics of laser cosmetology and plastic surgery Darus and Darus + provide the following services: Laser treatment for psoriasis and vitiligo, dermatitis and neurodermatitis treatment, eczema treatment, laser rejuvenation, laser hair removal, laser liposuction, laser peels, laser removal of any complexity pigment, laser tattoo removal, laser removal of warts, moles, warts, blood vessels,laser resurfacing, fractional thermolysis, acoustic treatment of cellulite, Beauty and body shaping, as well as plastic surgery: plastic face, blepharoplasty, abdominoplasty, mammoplasty,rhinoplasty, otplastik, liposuction.

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LEADERS

EO DENT DENTAL CLINIC Valentin Pavlov, Manager 16 Sveti Pimen Zografski str., Sofia, Bulgaria, 001172 phone: +359 24837072, +359 884454577 fax: +359 76601900 e-mail: [email protected] www.eo-dent.com EO Dent Dental Clinic and the Opportunity for Dental Tourism to Bulgaria.EO Dent is the largest chain of dental clinics in Bulgaria which offers a closed cycle of integrated diagnostics and treatment on the most advanced level. All that is necessary for safe and innovative dental treatment, you can obtain at the clinics. Over the years EO Dent has become a symbol of professionalism, continuous qualification improvement and a very special care and respect to the patient. The EO Dent clinics have all the facilities available for painless laser treatment, implants, aesthetic dentistry (veneers, zirconium structures, bleaching with ZOOM2!), 3D X-ray diagnostics, ultrasound diagnostics of the joint, HELBO therapy, specialized children’s rooms, and treatment under anesthesia.At EO Dent you can solve your dental problems for a wonderful week in Bulgaria. We offer a welcoming, luxury hotel accommodation and comprehensive care. With us, by modern anesthesia, you can fall asleep and wake up with a transformed smile – no pain and no memory of the intervention. The good collaboration with the dental lab we have, allows an individual approach and smile design. A quick and easy solution and most importantly – all in one place. The EO Dent clinics Sylvester Stallone trusted his smile to and when he walked away from Bulgaria he wrote on the wall – ‘For the great job! You are masters! With Love - Sylvester Stallone!In the TV show with Natalia Simeonova – ‘Pay It Forward’, the team of EO Dent transformed the smiles of many participants, made their dreams come true and gave them a new hope for self-esteem and confidence. It’s a policy of our clinics to conduct free treatment of children with disabilities and special needs. In the course of time, we have built a relationship of trust and friendship with these children and over the years this has become a unifying and inspiring cause for our entire team. EO Dent Dental Clinics have won prestigious awards – ‘Golden Seal’ for European management in healthcare and ‘Golden Book’ – for gained high prestige and contribution to the Bulgarian healthcare, an European award for Corporate Social Responsibility, served in Brussels, an award for innovation in ‘Esthetic Dental Surgery’ and the prize of nobility – ‘Charity Awards 2014’. EO Dent extends over 2,000 sq m, with bold and interesting interiors that create luxury and comfort to the patients. The greatest wealth is the EO Dent team – more than 200 outstanding professionals dedicated in patient care.The greatest achievement and the greatest pride are the smiles of our patients!

BUSINESS CARDS. INVESTMENT AND INNOVATION PROJECTS. COMMERCIAL OFFERS

ELKA SA Vrisera, Gjirokaster, Albania phone: + 355 8426 7301 fax: + 355 884 90099 e-mail: [email protected] www.elka-sa.com ELKA S.A. is operating in Balkans since 1993. Having as initial purpose the import and exclusive distribution of famous brands with Greek and International Presence, soon the company developed its own consumer goods, which easily gained important market share in the Balkan markets.In 2007, the company proceeded to an significant investment. ELKA S.A. acquired a pastry factory, which until then belonged to ION S.A., as well as the brand of the croissant Belino. Afterwards, the company increased its product portfolio with more SKUs of the brand Belino as well as of the 2 new brands.The company target is to provide customers with the highest quality products, which are being produced in one of the most advanced pastry factories in the Balkans, under strict specifications and certified quality.ELKA`s main activity is the distribution of consumer goods. The excellent organization of the distribution process constitutes the competitive advantage.Company guarantees to customers an integrated service for the whole range of our products in a continuous basis.Success and permanent economic growth is the result of the knowledge and long experience in combination with company`s energetic and creative spirit.To offer the customers an integrated service of excellent quality and not just products, managing to have a good geographic coverage of the Balkan market, ELKA S. A. have managed to remain one of the most well-organized companies in terms of distribution in the area.

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GREEN PLANET, LTD Rostislav Zheiliaskov, Director Pobeda Avenue, 68/1, fl 21, Kiev, Ukraine tel.: +38(044) 456-18-82 e-mail: [email protected] www.privetinter.net

Rostislav Zhelyaskov is a famous Ukrainian phytotherapist and educator. He was born on January 6, 1971. In his youth, he graduated from Odessa Automotive Technical School, after which he worked in this speciality. Later he took a full course of study at two faculties of Kharkiv National Academy of Pharmacy (now the National Pharmaceutical University). Currently he is preparing to defend his thesis. Rostislav was behind the creation, and is an active member, of one of the most famous Ukrainian associations of phytotherapists: the Ukrainian organisation and Environmental Society called ‘Green Planet’ and, operating under its auspices, the Ukrainian ‘Green Planet’ network of pharmacies. He has been a leading chemist of ‘Green Planet’ LLC, the pharmaceutical company that has made products for ‘Green Planet’ pharmacies for a long time, operating more than one hundred branches in Ukraine, and from 2011 has served as a director of the organisation. He was personally involved in the development of new drugs based on medicinal herbs, as well as improving existing recipes, doing much to popularise the achievements of traditional medicine and is a columnist on the ‘Green Planet’ online portal and forum. He is the author and co-author of several books on herbal medicine. He constantly improves his knowledge and participates in national and international congresses, pharmaceutical and scientific conferences and symposia on issues of quality and certification of medicines. Largely due to the personal contribution of Rostislav Zhelyaskov, ‘Green Planet’ drugs have won international recognition. These products are marked by the international award ‘European Quality’ (Oxford, UK), Certificate of the Institute of Quality Standards (Switzerland) and others. The personal achievements of Rostislav Zhelyaskov have also been marked in his homeland and beyond. Rostislav Petrovich was elected honorary professor at the International University of Vienna (Austria) and a member of the International Leaders’ Club (UK). He is the winner of the International Prize for research ‘The Name in Science’ with the his name entered on the register of the best scientists in the world, and a nominee for a number of national and international presentation publications. For contribution to the improvement of Kharkiv in 2009 he was awarded the honorary title ‘Kharkiv Citizen of the Year’ Among other honours Rostislav Zhelyaskov has been given the honorary award ‘Knight of the Motherland’, the Assembly of Business Circles of Ukraine’s personal contribution to the revival of Ukrainian spirituality, science and culture, and the title of Knight of the Order of the Knights’ Grand Master La Valletta (Malta).

Natalia Zemna (Zubitska), President of the Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, academician of the Ukrainian Ecological Academy, Professor of the International University of Vienna e-mail: [email protected]

An Academician of the Ukrainian Academy of the Environment, Natalia Zemnaya is almost the only representative of Ukrainian folk medicine whose achievements for the country have been marked by the highest state award - the Order of Merit, third degree. Mrs. Zemnaya is the winner of the International Scientific Prize ‘The Name in Science’ (UK), the V. Vernadsky Prize for significant contribution to the environment, an honorary professor at the International University of Vienna, the winner of the international competition for professional achievement ‘Name of the Year’ and winner of the ‘Lady of Mercy Knights of the Order of St. Lazarus’ (Malta) title. Among the healer’s assets are honorary awards from the Assembly of Business Circles ‘Saint Sophia’, the Order of Saint Vladimir Ukrainian Orthodox Church and other regalia. In 2013 she was awarded the highest distinction of EBA - the International Socrates Prize for contribution to intellectual development of Modern Society. Natalia Zemnaya belongs to the group of ascetics who revived the undeservedly forgotten tradition of folk medicine in the Soviet era, when this activity was not supported by the state. Then, in the years since Ukraine’s independence, the group has contributed to the synergy of centuries of national experience of herbal medicine and the achievements of modern scientific thought, leading to the development of herbal medicine as a science. The life and fate of this healer is an example of active compassion and overcoming difficult circumstances in life, courage, persistence and constant striving forward. From years of accumulated knowledge Natalia evolved a holistic concept of healing the body, which she sought to share with fellow countrymen. Her publications appeared in the press and her books became very popular. Over time, the healer was invited to create programmes for children and adults on radio and television. Thanks to this publicity she met many like-minded people. In 2000, these people (most had medical training) formed the backbone of a new public association – the public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’. Under its auspices, a successful pharmacy chain called ‘Green Planet’ began to operate and grow, which nowadays has more than a hundred branches around the country. There are now more than 200 patented drugs in the armory of the medical practitioners of ‘Green Planet’, the healing powers of which have been experienced by hundreds of thousands of people from all over Ukraine. Many of the medicinal formulations were developed by Natalia Zemnaya, both individually and in collaboration with colleagues. All the drugs are approved by leading pharmacists of the country. The activities of the healers of ‘Green Planet’ are recognised internationally. They have achieved prizes such as ‘European Quality’ and ‘Best Enterprise’ (Oxford, UK), as well as a certificate from the Swiss Institute of Quality Standards. For many years, Natalia has travelled around the different cities and villages of Ukraine, diagnosing illnesses and providing complex advice (for free!) for all who turned to her for help. And the reception is open ‘until the last patient’ has gone, sometimes late in the evening.

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HURLAG TECHNOLOGIES LIMITED Olasoji R. Olagunju, Managing Director/CEO 7, Ladipo Oluwole Street, Off Adeniyi Jones, Ikeja, Lagos phone: +234 8033078078 e-mail: [email protected] www.hurlag.com Hurlag Technologies Limited is an industrial engineering servicing company situated and incorporated in Nigeria. Over the years, Hurlag Technologies Limited has evolved to become the market leader in engineering services that ranges from Process pipe installations i.e fitting and welding of pipes using TIG, MIG with Argon gas to certified standards especially for food and pharmaceutical processing companies. Hurlag also specialize in construction and Installation of both stainless and mild steel tanks of various capacities and sizes. Cylindrical, Rectangular and Square Tanks. Our competitive advantage lies on our prompt and quality delivery with best engineering practice and bearing in mind extreme safety practice of at work place all the time.Hurlag is unique in Nigeria and entire Africa because of our experienced, highly qualified and trained Engineers. The TIG welders and fitters in our employment are highly qualified and we ensure periodic review of their certification to ensure constant quality delivery at all times. Some of the clientele are: 1. Nigerian Bottling Company (Hellenic group)2. Heineken3. Guinness Nigeria Plc (Diageo)4. GlaxoSmithKline5. Krones Ag (Germany)6. Nestle Nigeria Plc, 7. Seven-up/Pepsi Co Plc8. Brasserie Brewery Lome 9. IBK Groep, Netherlands10. GEA, Germany11. Waterleu, Belgium12. Pentair group, Netherlands. To mention a few.Hurlag’s Mission Statement is to be a technically innovative company providing an excellent Industrial Engineering Services to its various customers in an effective and efficient manner. To this mission, all its staffs adhere to ensure the market leadership currently attained.

INSOL D.O.O. Marko Licon, Owner and CEO Cankarjeva 16 a, SI-6230 Postojna, Slovenia phone: +386 59 95 9047 fax: +386 59 95 9047 e-mail: [email protected] www.insol.si Drydocks World is one of the most prominent names in the maritime industry. Over the past 30 years Drydocks World, Insol d.o.o. is a private enterprise engaging in research and development on the field of industrial eco-symbiosis. Company activities are focusing on the use of waste materials and waste energy for production of high added value products, with special emphasis on ensuring the efficient use of materials and energy throughout their entire life period. Highly trained professionals offering assistance in the developing of sustainable technologies, in promotion of environmentally friendly policies and in management of the environmental accounting. One of the company’s core business activity is offering assistance in hazardous chemicals and waste management for the small and medium-sized enterprises that do not have their own R&D departments. For the development purposes Insol d.o.o. is cooperating with Slovenian and international experts in various fields. Company experts are honorable speakers at international conferences, and authors of international scientific publications and more than ten patents on the field of sustainable development. In past few years Insol d.o.o. have been awarded with international awards for their contribution in the quality management.

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ISIDA HOSPITAL Viktor Zinchenko, Deputy CEO phone: 0 800 608080, +38(044)4558811 e-mail: [email protected] www.isida.ua Isida Hospital. Professional care for women.Isida is a leading specialized hospital of women’s health combining obstetric-gynecology complex and three outpatient centers. Medical centers Isida are specialized in infertility treatment, obstetrics, gynecology, mammology and pediatric nursing – that is a large variety of medical services for woman and for infants. The hospital has international quality certificate ISO 9001 confirming not just the level of the specialists but treatment standards as well. Strict keeping to the standards is one of the work principles of the Hospital.HistoryIsida was founded in 1992 in Donetsk as an infertility center. In 1995 its branch was opened in Kiev. In 9 years first private obstetric-gynecology complex was established under brand name Isida (boulevard Ivan Lepse, 65).In September 2010 Isida opened outpatient clinic in Kiev, Obolon district. During next two years such outpatient centers appeared in Donetsk and Kiev on the left bank of the Dnieper.Isida is quite known on the international market. As a result of high level and professionalism of the specialists we have close collaboration with leading foreign clinics of this field and patients from more than 32 counties of Europe and Northern America.SpecializationIsida Hospital has everything necessary for prophylactics and treatment of gynecology diseases, pregnancy care and care for the newborn during his first hours and days. Narrow specialization lets us take care of a woman and family during crucial life moments.Having expertise and providing high quality medical services we actively realize the principle of succession of different departments and services of the Hospital, in particular between gynecologists of outpatient department, doctors of delivery unit, neonatologists and then pediatric patronage. Due do such succession we get good medical results and create maximum comfort conditions for a woman.Activity areasWomen’s health. We know and understand unique female nature as nobody else and we are able to keep and restore it in case of any problems. We provide wide range of services for young ladies and women, so there is no need to apply to any other medical institution. We create better future for a girl, woman, mother, grandmother keeping their health from youth to ripe years.- Gynecology and prophylactics. Prophylactics, timely diagnostic and treatment of all range of gynecology diseases. We have special equipment for outpatient treatment of cervix diseases.- Gynecology surgery. All types of gynecology surgeries are carried out in a modern surgery complex.- Mammology. Prophylactics and treatment of breast problems including surgeries.- Infertility treatment. Diagnostics and medical infertility treatment, assisted reproductive technologies (IVF, ICSI, PGD). Psychological patient counseling.Pregnancy monitoring and delivery. Outpatient pregnancy monitoring, prenatal screening, 24 hours hospital admission if necessary. Fully equipped obstetric complex. There is intensive care unit, neonatology department (development care for premature babies), newborns screenings, and vaccinations. There are different courses for pregnant women helping to get ready for baby birth. Pediatric patronage service. Patronage pediatric service on the infant. Vaccination. Lab diagnostic. Our own clinical-diagnostic laboratory and genetic laboratory. We carry out hormonal, immune, cytological, cytogenetic, biochemical and many others examinations.Why ISIDA?- team of experienced doctors from different medical spheres;- solid diagnostic base;- our own lab with big examination potential;- prove list of diagnostic services;- possibility to choose maximum suitable diagnostic programme;- careful concern about each patient;- perfect service, comfort staying facilities.BranchesObstetric-gynecology complex – 65, bld Ivan Lepse, Kiev, Ukraine.Outpatient department #1 – 22, Geroev Stalingrada, Kiev, Ukraine.Outpatient department #2 –8-Б, Raizi Okipnoi, Kiev, Ukraine.Branch – blv Panfilova, 21/4, Donetsk, Ukraine.

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WELLNESS CENTER OF MASSIMOV LLP Kazhimkan Massimov, Director General 91, Abay Avenue, Almaty, 050022, Republic of Kazakhstan phone: +7 727 387 13 11 fax: +7 727 399 98 61 e-mail: [email protected] www.healthcm.kz Wellness Center of Massimov was created in 2003. From the moment of establishment the main activity directed оп introduction and use east medicine methods and improvement of а physical and spiritual health of Kazakhstani citizens has being conducted. Center’s activity is directed оп а combination of traditional and alternative medicine methods. In 2011 new direction of activity was opened - medical equipment distribution and pharmaceutical activity, also Center began to develop medical tourism direction. In 2011, LLP ‘Wellness Center of Massimov’ together with South Korean introduced new technologies for early diagnostic of cervical cancer in Kazakhstan and working on this project fruitfully for 2 years. On 27 December 2012, the Center opened the factory of production of rapid tests and chemical reagents in the joint technology between companies LLP ‘Wellness Center of Massimov’, Kazakhstan and Bio Focus Co., Ltd., South Korea. In 2013, WCM for the implementation of the state program on screening to identify the cervical cancer gratuitously transferred diagnostic equipment of Liquid Based Cytology to all 16 areas of the Republic of Kazakhstan. In spring of 2013, WCM presented to the Ministry of Healthcare of the Republic of Kazakhstan screening method for the determination of tuberculosis by rapid-tests diagnosis and liquid-based cytology. In 2014, based on the LLP ‘Massimov Wellness Center’ was established Centralized Cytological Laboratory (CCL), which coordinates the activities of Cytologists for the Republic of Kazakhstan as well as being educational preparatory and consultation center with attraction of experts and scientists from South Korea, USA, Japan, Turkey and other countries of near and far abroad.

JORDAN INSURANCE FEDERATION Maher Marwan Al-Hussein, Federation Director PO box 1990, Amman, 11118, Jordan phone: +962 65689266 fax: +962 65689510 e-mail: [email protected] www.joif.org

Jordan Association of Insurance Companies has been established in 1956 as the first commission regulating insurance sector affairs in Jordan, the federation presidency was headed successively by several commissions with the membership of pioneering workers in the field of insurance in that period. Where as in 1987, the unified compulsory insurance office for motor insurance has been established and began to exercise its activities under the supervision of the association while the association remained operating its activities until 1989, when Royal

Decree was issued to establish Jordan Insurance Federation and determine its statute to organize and manage insurance sector according to the objectives set by this statute, in addition to work to achieve them in collaboration with the insurance Commission. In 2008 a new statute was issued to replace the one issued in 1989, accordingly restructured the formation of the federation board was issued in addition to the objectives identification and reshaping. There are 32 Compulsory Unified Insurance Offices which they perform all works related to the insurance of Jordanian vehicles through its offices in Licensing Departments all over the Governorates of Jordan as well as insuring transit cars at borders centers from civilian liabilities’ risks in accordance to vehicles compulsory insurance regulation. The office also distributes the shares of compulsory insurance of Jordanian vehicles tenders among insurance companies and settles down their accidents as well as settling down the accidents’ claims of Arabian vehicles insured with Orange Cards and Jordanian vehicles insured at unified insurance offices in the Arab countries. Joif has launched in 2013 his initiative The new Electronic Traffic Accidents Reporting System (ETARS) in Jordan in cooperation with Public Security Directorate which aims to providing data and photos for insurance companies to settle motor claims and stemming fraud in this branch. This step came after the success of issuing TPL policies online on behalf of insurance companies since 2005

through NEMIS ( Nationwide Electronic Motor Insurance System) which made clear difference in the insurance industry in Jordan in terms of speed, accurateness and online keeping companies updated with the new issued policies up to date. The Federation has become one of the most prominent entities in the region and is deemed to be the most active one in terms of continuous development and follow up with the industry needs and gained high reputation in the international and local activities and conferences organized by the Federation which attracts the leaders of insurance and reinsurance companies around the world who mark their agendas to participate in the gatherings organized by the Federation. JOIF has also strengthened his relations with both public and private sectors in Jordan and is looked at to be one of the most successful entities .

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MEDICAL CENTER AND LABORATORY NADEJDA Nadya Dyulgerova, Owner and manager General Kolev 66, Varna, Bulgaria phone: + 359 52 62 76 26 MC NADEJDA ‘Doyran’ 6, Reception phone + 359 52 64 82 28 MC NADEJDA ‘Gen.Kolev’ 66, Reception phone + 359 52 60 99 32 MED.LABORATORY, Reception phone/fax. + 359 52 60 97 41 e-mail: [email protected] www.nadejda-bg.net Medical Center /MC/ NADEJDA was created in 1999 as a healthcare establishment with a main activity being the specialized outpatient care, and having its current address and head office of management in Varna. In 2002 a clinical laboratory was established at the center, which is furnished with equipment of leading world laboratory companies. Consistently there has been a microbiological laboratory, parasitological laboratory, mycological laboratory opened to the laboratory, and a DNA diagnostics field has been developing. As from 2009 there successfully has been working the second base of the center in Varna too. The center has been registered as a sole – owner LLC after the Commercial Act and the Law of hospitals. Owner and manager of the center is Dr. Nadya Kancheva Dyulgerova. Service AccomplishmentsMedical Center Nadejda strives to provide its patients with:• High quality health care, equal and ready access to medical specialists;• Precise and efficient diagnostics through the use of new technologies and equipment;• Accurate results that help increase patients’ trust;• Check-ups for individuals and for company staff, at the request of the company’s management;• Conditions for rising patient satisfaction from the quality of the received health care, with the goal that Medical Center Nadejda be their first choice of health care facility.Medical Center Nadejda provides ambulatory health care to patients of all ages, male and female, residing in or visiting Varna, Bulgaria or Northeastern Bulgaria. Nadejda services approximately 2,000 patients per month, on average. The core demographic that Nadejda serves is patients who have already chosen to frequent Nadejda based on their good impressions as a result of interacting with Nadejda’s medical specialists, obtaining fast and accurate results, or receiving recommendations to come to Nadejda from other satisfied patients.Medical Lab Nadejda has also expanded its diagnostic capabilities too and now performs: Hematological, urological, immunological, virus-related, microbiological, mycological, parasitological, hormonal, and DNA tests, Cancer screenings.

MAXIDOR SA (PTY) LTD Miklуs Hegyi, Chief Executive Officer P.O. Box 11268, Randhart, 1457, Republic of South Africa phone: +0860 131 131 fax: +27 11 617 0444 e-mail: [email protected] www.maxidor.co.za Maxidor SA (Pty) Ltd - Domestic, Commercial, Industrial Expandable Safety and Security Barriers. The company occupies a call centre in Bedfordveiw and six commercial/industrial buildings in Johannesburg, Cape Town and Durban and a branch office in Pretoria. (the total sqm : Land : 30,650 meters , Buildings: 20,519 meters). The operations include 16 national and international agents and franchises, as well as an extensive export network. Exports are done to all major African countries such as Botswana, Kenya, Ghana, Angola, Madagascar, Nigeria, Zambia, Namibia, Mauritius and Mozambique. Other countries include New Zealand, UK and Israel. Since 2002, Maxidor SA (Pty) Ltd has received nine (9) ‘Top 300 Companies’awards (In association with the South African Department of Trade and Industry). From 2004, Maxidor SA (Pty) Ltd has consistently been in the Top 50 of the annual ‘Deloitte & Touche’ ’Best Company to Work For’ survey. Maxidor SA (Pty) Ltd has a mission to provide the best possible security to as many families, individuals and groups as possible. Maxidor’s commitment to that mission is evident in their remarkable growth of over 300% since 2001. Maxidor SA (Pty) Ltd has set the standard in the Physical Security Barrier Industry, (e.g. Slamlock (invented by Maxidor) and Buy-Back Guarantee, are widely recognized by the market as the highest standards available). Maxidor SA (Pty) Ltd today is the product of remarkable vision and the resolute application of business principles. Every resource and infrastructure component listed below forms part of an intricate synergy which continues to achieve dramatic success. NATURE OF BUSINESSDescription of activity:Marketing, Sales and Manufacturing of Physical Security and Safety Barriers.PRODUCTS/SERVICES OFFEREDManufacturing, Supply and Installation of mild steel expanding security doors, security gates, security grills, roller shutter doors and safety barriers.

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MEDICAL CENTER GAJDA-MED Robert Gajda, Director Piotra Skargii 23/29, 06-100 Pułtusk, Poland phone: +023 692 13 70, +023 692 02 07 fax: +023 692 01 99 e-mail: [email protected] www.gajdamed.com.pl Robert Gajda, Medical Doctor, PhD is the director of the Medical Center Gajda-Med, its founder and charismatic leader with outstanding skills. His adventure with sport, more important than learning at that time, began already in primary school. At the beginning of the second grade of high school, started his first serious achievements in cross-country and middle-distance runs. This is how his adventure with feats in sport began. In high school, he practiced middle-distance runs and won numerous champion titles of the province. In 1982, being at the top of his powers and certain to win the gold medal, he did not pass through eliminations during the Indoor Championship in Athletics of Poland in Zabrze.At that time, he understood that sport should be an extra activity rather than life purpose. It is sport that taught him to look for his opportunity over and over and forget about shortcomings. It is sport that shaped his spirit showing him the taste of victory and that it is worth every effort to feel it as often as possible. As intensive as his trainings were, as intensively he started to study, which was reflected in good results of his school leaving exams and entrance exams. As a result, in the same year, 1982, he began medical studies at Medical Academy in Białystok simultaneously continuing to practice running. Throughout his studies, he represented the academy during running competitions in Poland and abroad. In 1988, he graduated with high average grade and underwent internship in the Regional Hospital in Maków Mazowiecki, and from 1990 to 1998 he worked in the department of internal diseases in the Regional Hospital in Pułtusk where he acquired further specializations.In 1992, he passed a first level specialization in internal diseases exam with an excellent result. A year later, he defended his PhD dissertation titled ‘Activity of granulocytic alpha- amylase in certain inflammations’. PhD conferment procedure was conducted in the Medical Academy in Białystok. In the following year, after the Health Minister’s consent to shorten his internship, he passed a second level specialization in internal diseases exam with a very good grade. Shortening of the internship was issued by his specialization supervisor due to dr. Gajda’s substantial scientific and professional activity along with his good grades obtained in partial internships. In 1995, he commenced sub-specialization in cardiology and completed it two years later. In 1997, he opened his cardiologic clinic, which he runs presently. In 1998 he completed specialization of family medicine and in 2008 specialization of sports medicine, which is his fourth second level specialization. In 1998, he decided to provide a more stable future for his family and created the clinic Medical Center ‘Gajda-Med’. A few years ago, in Medical Center Gajda-Med, a sports cardiology clinic was established, which is a highly specialist clinic functioning as a clinic for high-performance athletes from all over the world and for amateur sportsmen. Due to high demand for such services and their dynamic development, the clinic was transformed into a Sports Cardiology Center. The Center was created for athletes whose sports career as well as preliminary and controlling qualification depends on professional assessment of circulatory system. The Center is also a scientific-research unit where he conducts researches into the influence of physical effort on athletes’ hearts, in particular long-distance and marathon runners’. The researches are conducted in cooperation with the best cardiologic centers in Poland.

HOSPITAL ‘MEDISTYLE’ Gafur Jafarov, Director General 116 Acad. GasanAliev Street, Baku, AZ10000, Azerbaijan phone/fax: +99412 465 73 01 e-mail: [email protected] http://www.msh.az, www.facebook.com/medistyle.az/info ‘MediStyle’ clinic was opened in 2007. It is equipped with the advanced equipment answering to the world standards. Main kind of activity in the clinic is plastic and general surgeries, gynecology, ENT.Now it is functioned 11 operating rooms, equipped by the most modern equipment at ‘MediStyle’.More than 300 different operations are made in a month. It is possible to place 120 sick people there.In May, 2012 it was opened a new branch of ‘MediStyle’ hospital.

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NATIONAL SCIENTIFIC MEDICAL RESEARCH CENTER JSC Abai Baigenzhin, Director General 42, Abylaikhan avenue, Astana, 010009, Republic of Kazakhstan phone: +7 717 223 11 90, +7 717 257 76 11 e-mail: [email protected] www.nnmc.kz National Scientific Medical Research Center JSC is one of the leading research clinics in the Republic of Kazakhstan. Our clinic for 13 years is a leading medical institution providing high-quality medical care to the population, combined with the research process and new methods introduction of diagnostics and treatment.Management system of NSMRC is certified according to the level of EFQM Models ‘Recognized for Excellence 5*’.The center’s staff is the team of researchers, doctors, nurses and supportive staff which aimed to achieve three main goals: to provide patient care, development of medicine as a science and practical training of medical personnel.NSMRC actively implements transfer of innovative technologies in the Republic of Kazakhstan in cardiac surgery for the treatment of complex forms of heart rhythm disorders, organs and tissues transplantation.NSMRC is the coordinator of the international multi-center clinical trials, for example clinical trials using stem cells in the treatment of acute myocardial infarction, diabetes, liver disease (results presented in SWISS Medica (FDA), FDA (USA). Clinical trials are conducted in accordance with the requirements of GCP.

NANOPAC (M) SDN BHD Dato’ Dr. Cheng Kok Leong, Chief Executive Officer 27 Jalan Rajawali 2, Bandar Puchong Jaya, 47100, Puchong, Selangor, Malaysia phone: +603-8070 7428 fax: +603-8076 6487 e-mail: [email protected] www.nanopac.com.my Malaysia’s pioneer in developing and manufacturing nanotechnology-based products, Nanopac (M) Sdn Bhd is a joint-venture between a Malaysian and South Korean party. The company was established in November 2003 and subsequently granted pioneer status in high technology by Malaysian Industrial Development Authority (MIDA) a year later.The products manufactured by Nanopac are developed based on the cutting-edge nanotechnology. Nanopac managed to combine two technologies – nanotechnology and photocatalyst technology – to create a variety of nano solutions that could be applied to any product or surface in highly diversified industries with the purpose of killing bacteria, germs, viruses, biological toxic gases as well as cleaning up the environment against pollutions. Using this powerful hybrid technology, high-end products are developed such as nano-hybrid filtration system, medical masks, hygiene toiletries and personal care products, apparels, construction materials, fertilizer and many more. After more than 10 years of aggressive growing under the management of CEO, Dato’ Dr. Cheng, Nanopac has risen to be a regional leader in nanotechnology industry. The company now has strong oversea networks covering United States, Europe, Australia, China, Japan, Bangladesh, Middle East and South East Asia region. Among the prominent business partners are Samsung, LG, Hitachi, TCL, 3M, Haier, Electrolux and Khind. With the convergence of nanotechnology and green technology, the renewable energy industry is set to gain greater traction in the mainstream economies worldwide. Relevant to that statement, Nanopac is taking an exemplary and leading role in this sector through its latest nano-based solar cell technology and it is the first Malaysia’s nanotechnology-based renewable energy success story.

KYZYLKUM TYULPAN

Natalya Akhmadulina, Director 71, Avtomobilnaya Str, Navoiy, 210104, Republic of Uzbekistan phone: +99 891 337 07 44

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NEAR EAST UNIVERSITY HOSPITAL Assist. Prof. Dr. Irfan Gunsel, Chairman of the Board of Trustees Near East Bulevard, Nicosia, TRNC, Mersin-10, Turkey Turkish Republic of Northern Cyprus phone: +90 392 675 1000 / 1903, +90 542 876 84 84 www.neareasthospital.com The Near East University Training and Research Hospital with its 41 departments has been established on the campus of Near East University, Lefkosa, North Cyprus. Within its future-oriented structure, it serves patients from all over the world. The hospital’s state-of-art infrastructure experienced medical and support staff and unmatched technology are at international standards only seen at its western counterparts. The NEU Hospital was planned as a patient-centered institution. The international standards according to the Joint Comission International (JCI) have been adopted in advance to become a world-class center to realize medical and other services for the patients.It has a 55,000 square-meter closed area, consist of 3 blocks. The western block has 3 section, which includes the hospital services, emergency service, radiology, nuclear medicine, 8 operating theatres, 30-bed Intensive Care Unit, 17-bed Neonatal Intensive Care Unit.The 9 floor middle block consist of laboratories, hemodialysis service, blood bank, administrative offices and patient single room with a capacity of 250 beds of which 22 are VIP suits.The eastern block consist of radio therapy, physical therapy and rehabilitation units, drug preparation and distribution section and the service departments for outpatients.To fulfil the diverse needs of the international patients an ‘International Patient Coordination Center’ has been created. This facility arranges and coordinates the transfer of international patients and their companions to and from North Cyprus. Further more appropriate accommodations by translators will help them to communicate in their own languages. The Centre also arranges tours and social activities within the country. The objective of the Centre is to send the patients back their homes as healthy and happy individuals.The Near East University boasts with many ‘Firsts’ in Cyprus. The NEU Hospital’s achievements are:The first and only private university hospital.The first and only high-tech Radiotheraphy Center (Rapid Arc Technology).The first and only PET/CT.The first and only reference laboratory where all medical tests can be performed.The first and only HIS, RIS and LIS digital computer systems.The first and only air-jet ambulance.

NOBLE SMILE DENTAL CARE CLINIC Ahmed Mohammed Shamiyah.BDS.MSc.FIDc, Owner and Medical Director Shaikh Abdullah Al – Ankari Road, Al-Worood Area, Riyadh, K.S.A, POBox, 258334, Riyadh 11323, Saudi Arabia Kingdom phone: +00966114197740 mobile: +009665040509111 fax: +00966114197710 e-mail: [email protected] www.noblesmile.com.sa Noble Smile Dental Care is a high standard of care oriented practice in the heart of Riyadh city the capital of Saudi Arabia. Our team consist of dentists and nurses with international education to provide our patients with the upmost care utilizing the latest dental technologies. We have computerized information system for the complete privacy of our patient’s health records. Complete patient involvement in health strategy, work plan, time line and Progress monitoring. Our multidisciplinary team approach makes NSDC unique in providing comprehensive dental, cosmetic and maxillofacial care.Noble Smile Dental Care is accredited by many national and international firms and business groups. Noble Smile Dental Care team serves many Diplomatic representatives with in the Kingdom of Saudi Arabia. Noble Smile Dental Care Clinic received the International Star Award for Quality – Gold Category in 2013. Noble Smile Dental Care Clinic received the Diamond Eye Award for Quality and Excellence in 2014.Noble Smile Dental Care Clinic received the International Star Award for Quality – Platinum Category in 2014.Our vision: To upgrade the level of dental and oral health care.

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NEW LIFE GLOBAL NETWORK Mariam Kukunashvili, Founder Bakhtrioni 11 B, 000179, Georgia phone: +995 0 32 62 01 01 e-mail: [email protected] www.newlifegeorgia.com New Life Georgia provides services in the field of infertility treatment with the help of the latest assisted reproductive technologies. At New Life Global Network we are committed to helping individuals and couples to bring a child into their lives. We are doing our best and everything possible to assist local and international, straight, LGBT and HIV-Positive intended parents realize their dream of having a child. Since 2008, more than 500 healthy babies were welcomed into loving homes with the help of New Life Global Network. Our IVF specialists have helped many couples from various countries including Australia, Europe, UK, India, China, Japan, Canada and the USA and we will be happy to help you too. New Life Global Network fertility centers currently operate in Georgia, India, Ukraine, Armenia, Israel India Thailand Mexico United States and Estonia. New Life Georgia, India, Thailand and Estonia are well-known full service fertility clinics done in equal partnership with Estonian Partners. New Life Ukraine, Armenia and Israel are solely Surrogacy and Egg Donation centers with further plans of having IVF clinics as well as soon as possible. For last several years, New Life has built families by leading in the field of Advanced Reproductive Treatments. We specialize in the management of all areas of infertility. It is worth to mention that we place a strong emphasis not only on the quality of medical care, but on emotional concerns of our patients as well. New Life provides a variety of world-class, affordable treatment through incorporating the latest technologies in a patient-friendly and confidential environment using our intelligence, commitment, and experience.Advantages Variety of Options - India, Georgia, Ukraine, Thailand. One of the greatest advantages of choosing our global network is that you are not limited with specific country for your treatment destination. Being network of world known fertility centers located in different countries enables New Life Global Network to provide fertility treatment services in various countries: in India, Georgia, Ukraine or Thailand. You can choose a country of your destination according to your geographic location and personal preference. You will get the same high standard care in any fertility centers united in our global network. Affordability We strongly believe that each person deserves joy of parenthood and the financial factor should not be a barrier to this happiness. Therefore, we are striving to keep our program costs as low as possible. The program fee is usually paid in several installments. Moreover, our surrogacy programs are cost effective since we provide successive matching with additional surrogates if your initial surrogate is not following the medical stimulation successfully. We usually prepare several surrogate mothers for each program without any extra costs that ensures increased chances of success. Convenience You don’t need to come to India, Georgia, Ukraine or Thailand for your paperwork in order to start the program. We provide opportunity to sign the agreements via e-mail. Moreover, you don’t have to arrive to any of these countries for your initial medical evaluation as well. You can send the scanned copy of your medical results and our doctor will review it free of charge. This way you can save your time and money and avoid any extra efforts. Egg Donors from Europe and Asia Travelling for Your Program. We have large database of egg donors who are willing to travel to your location for your program. Our outstanding database of Caucasian and Asian egg donors and qualified services are highly recommended by top fertility physicians all over the world. New Life Global Network provides the best conditions for both egg donors and intended parents. Our goal is to provide the highest degree of care to recipients and egg donors equally. We offer one of the largest and most comprehensive egg donor database were each donor is carefully screened and personally interviewed. All of our donors are contacted regularly to ensure their availability and information is up to date. We strive to maintain a diverse egg donor pool including Ukrainian, Asian, Georgian, South African, Polish and Indian Egg donors. It is worth to mention that during last several years our egg donors are flying abroad to different destination according to patients and their world famous physicians request. New Life already proved itself as a most trustworthy and reliable network of fertility clinics in the world. Large database of Surrogate Mothers We value your time and keep large pool of surrogate mothers ready for your program. We can assist you in finding healthy, dedicated and trustworthy surrogate for your baby in short period of time. Our surrogates meet an extensive list of qualifications: complete medical, psychological, and laboratory evaluation and undergo a background check to be considered a surrogate. Each of them undergoes uterine assessment by qualified doctor before confirming for the program.Comprehensive Assistance Our coordinators and medical staff work closely with each intended parent to ensure arrangements are customized to meet their specific needs. We do not focus sole on the medical aspects of assisted reproduction. We provide education and support services to intended parents. They receive personalized, attentive and knowledgeable assistance with each step of their fertility program. We facilitate every aspect of your program to ensure it goes smoothly. We are striving to take this journey with you from the very beginning until you take the baby home to make sure you have all the support you need through the way. Direct Communication We put significant emphasis on counseling for both the surrogate mother and intended parents. Our professionals will provide you full information about alternative treatments, cost of the treatment, potential medical and psychological risks involved, as well as implication for multiple pregnancies. Our doctors are available for direct communication and you are more than welcome to discuss your program details not only with program coordinators, but medical staff as well.Excellent Success Rate Carefully and fully pre-screened surrogates and egg donors, experienced medical staff and dedicated coordinators are all that contribute to our high success rate. We have more than 500 babies born in our network and are welcoming more and more in every single month.

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1st PERINATAL CENTER OF ASTANA Dina Turakbayeva, Chief Medical Officer Turar Ryskulov str., 8, Astana, 010000, Republic of Kazakhstan phone: +7 7172 43-27-42 fax: + 7 7172 43-27-30 e-mail: [email protected] www.pc-1.kz State Enterprise on a Full Economic Control ‘Perinatal Center 1’ of Astana akimat is located on the left bank of the river Yesil and determined as the third level of perinatal care in the structure of urban obstetrical organizations, taking into account the degree of medical equipment, medical staff, the presence of the second stage of newborn care and neonatal surgery. The Enterprise has an excellent logistical base and human resources. Consultative and diagnostic unit is designed to resolve all issues relating to pregnancy, family planning and gynecological diseases. Existing potential of human and logistical resources of the organization allows to be competitive medical enterprise. Accommodation in a consultative and diagnostic unit separation of family planning and Genetic counseling allows to provide diagnostic and therapeutic help to infertile couples on the principle of ‘one window’, including inpatient care, and perform a large amount of consultative and diagnostic care in case of genetic and chromosomal diseases, congenital malformations and other abnormalities with the use of modern technology.

POLYCORP LTD Peter Snucins, Founder, President and CEO 123 Front St. W. , Suite 905, Toronto, Ontario, M5J 2M2, Canada phone: +1(416) 364-2241 fax: +1(416) 364-9880 mobile: (416) 804-4384 e-mail: [email protected] www.poly-corp.com Polycorp Ltd. is a privately owned, ISO 9001 Certified, Canadian Company (a successor company of B.F. Goodrich Engineered Products) that specializes in the design and manufacture of engineered elastomeric parts that provides its customers with high quality, cost effective solutions to corrosion, abrasion, impact, noise and vibration problems. Polycorp has built eminence, and a reputation, as a global market leader, in three distinct areas: Mining (Grinding Mill Liners); Industrial (Protective Linings); and Transportation (Track Encapsulation Systems). Polycorp has developed engineering solutions that increase customer productivity, reduce maintenance downtime, and solve complex technical challenges, with its products currently in 34 countries worldwide. Since its inception, Polycorp has been the beneficiary of the 95 years of experience in manufacturing, research, compounding, and testing of B.F. Goodrich, a base upon which Polycorp has subsequently expanded. Polycorp’s engineers and technicians continually expand the polymer portfolio, simplify the formulations, and work with a variety of laboratories and suppliers to enhance their properties. The emphasis on intellectual property development has resulted in 11 active patents and 11 patent applications pending, many of which have been filed in multiple jurisdictions. Recognized as one of Canada’s Best Managed Companies (2011, 2012 and 2013), and by PROFIT 500 for 2012 and 2013.

PRIVATE MEDICAL PRACTICE SARCLINIC Vladimir Pechennikov, General director Moskovskaya Street, 152, Saratov city, 410012, Russian Federation phone: +78452606060. +78452606061 e-mail: [email protected] www.sarclinic.ru ‘Private Medical Practice Sarclinic’ was founded 22 years ago. The centre combines new fruitful theoretical elaborations and wide experience of successful practice. During the existence of the centre in Saratov thousands of men, women and children took treatments and returned to a healthy life. The centre is situated in a comfortable building in Moscow Street. A complex approach in treatment is practiced in our centre. We combine modern methods of Russian, European and American medicine with ancient traditions of Eastern and traditional medicine. We widely apply different methods of reflex therapy that assists to achieve excellent stable results in the treatment without side effect and complication. The treatment is held on the level of the world standards. The equipment used in the centre has been produced on the basis of the latest achievements of the high technology industry. We provide treatment of male and female sexual disorders, infertility, inflammatory diseases of genitourinary apparatus, nervous system diseases, dependence state (alcoholism, smoking), illnesses of spine, muscles and joints, metabolism disorder, infantile sicknesses, diseases of digestion organs and other illnesses. Individual approach and attention to every patient is the basis of our work. ‘Private Medical Practice Sarclinic’ has been registered as ‘The Best Medical Institution of the Russian Federation’ medical list of 2012, 2013.

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DR ORAL B. OSPANOV, PROF President of Association of Endoscopic Surgery of Kazakhstan (AESK) Head Department of Endosurgery of Astana Medical University 5/1, Syganak Str, ap. 48, Astana, 010016, Republic of Kazakhstan phone: +7 701 528 77 34 e-mail: [email protected] Born on October 30, 1961 in Omsk region of Russian Federation (Russia).Skills of the open and laparoscopic operations (surgical procedure) of general and abdominal surgery. More than 20 years experience in the use of laparoscopic and thoracoscopic procedures.Author of 157 publications (in Russian and English) and 20 inventions. Scientific interests:Laparoscopic Surgical Repair of Hiatal HerniasLaparoscopic Antireflux procedure for GERDLaparoscopic Bariatric and Metabolic SurgeryLaparoscopic Surgical procedure for Achalasia EsophagusInvention Laparoscopic suturing devicesUse Compression Anastomosis Clip Application in Surgery.Honorary state titles:‘Best teacher of higher educational institutions of the Republic of Kazakhstan for 2012’, awarded by the Ministry of Education and Science of the Republic of Kazakhstan;‘Honored Inventor of the Republic of Kazakhstan’ awarded in 2013 by the Ministry of Justice of the Republic of Kazakhstan.

HEALTH AND WELLNESS COMPLEX ‘SAILAUKHAN’ Republic of Kazakhstan phone: +7(727)225 38 22, 225 38 29, 294 61 72, +7( 701) 179 06 06, +7(701) 432 34 55, +7 (702) 962 78 93, +7( 747) 429 46 60 e-mail: [email protected] www.sailaukhan.kz Sailaukhan is an international healer.Your health is in our hands! Health and wellness complex ‘Sailaukhan’ works since 2006 and it is one of the leading establishments of Kazakhstan which presents qualitative medical services by means of development of new technologies and modern directions in alternative medicine. All medical activity is realized on the basis of famous doctor of rehabilitation medicine Sailaukhan Auelbayeva`s unique author`s methods. Effectiveness of this unique method was proved repeatedly in the course of large research scientific work and enormous results were achieved during treatment of the most different diseases including intractable as pancreatic diabetes and oncology. An exact informational diagnostics, individual program of non-drug treatment which intended for elimination of reason and also prophylaxis and rehabilitation are held in medical complex. Medical establishment is equipped with modern laboratory-diagnostic basis. All medical process include whole system of health improvement – water treatment with the help of medical water ‘Sailaukhan Su’, music therapy, dry energy sauna; production of medical things and many others is put. Health complex develops new projects every year. Opening of medical spring, museum ‘Sailaukhan’, branch of her own sewing shop in Aktau city and participation in agro-industrial sector are among them.Joint work is carried on parallel with scientists-medics, representatives of alternative medicine of Ukraine, Russia and Great Britain. Health complex was awarded international recognition for development of author`s methods, weighty contribution to system of public health and received badges ‘European quality’, Swiss quality, it speaks about its meaningfulness and right chosen way.

ORDABASY KUS LTD Murat Tagayev, Director General Badam Street, Badam Village, Ordabasy District, South-Kazakhstan Oblast 160601 Republic of Kazakhstan phone/fax: +7 725 294 74 03 e-mail: [email protected] www.indeika.kz Branch of industry: Agriculture, Food industry. Number of personnel: 400. Year of foundation: 2007The principal activity of the Company is: growing tribal turkey, turkey meat production, processing and marketing of complete finished products in an assortment of turkey, sausage and smoked turkey products to consumers.

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SAUDI GERMAN HOSPITAL DUBAI Reem Osman, CEO Barsha 3, Hessa Street 331 West Off Exit 36 Shiekh Zayed Road, Opposite of American School of Dubai, P.O Box 3919093, Dubai, UAE phone: +971 4389 0000 fax: +971043890505 e-mail: [email protected] www.sghdubai.com SGH Dubai is an integral part of SGH Group, the leading healthcare provider and Number one healthcare brand in the MENA region starting in Jeddah KSA in 1988. Currently SGH Group has six operating hospitals. At present our family members comprised of 39 nationalities. We have over 110 physicians on board till date and gradually adding more as per the need of the hospital and the market. It is the only hospital in the region having following three accreditations simultaneously• JCI ACCREDITATION;• CAP ACCREDITATION;• MEDICAL TRAVEL QUALITYAWARD(MTQA).SGH Dubai is located in Al Barsha area. SGH Dubai was officially inaugurated on March 19, 2012 by HH Mohammed bin Rashid Al Maktoum and since then we are progressing ahead with high motivation and great success. SGH Dubai is a 315 beds tertiary hospital and the main concern is to provide its most advanced medical care to its patients through a highly professional team using the best available technology. We have a great experience in all specialties and subspecialties with a state of art equipment and technologies making SGH Dubai a one stop shop that serves and cares for our community (Locals and Expats). At present it is five floors high premised with all the medical facilities. Our expansion plan is to have a medical tower that accommodates 215 leased clinics, 6 specialized medical centers and an immense Educational Centre that all form a medical city.SGH Dubai Specialized Care Units. Diabetes Unit: SGH Dubai has a dedicated team of endocrinologist, clinical nutritionists, retinal physicians, Nephrologist and vascular surgeon that provides a comprehensive care to the patients using multi-disciplinary approach for the evaluation, management, and education by a team of medical and clinical experts. Pulmonary and Critical care Unit: SGH Dubai has a state of art pulmonary and critical care unit with 28 beds being the biggest ICU facility by any private healthcare facility having 24/7 coverage by a highly qualified team of intensives. It provides screening and treatment of chronic and acute respiratory disease like asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, chronic respiratory failure, pulmonary vascular diseases, pulmonary embolism, pulmonary hypertension (high blood pressure in the lungs) by a multi-disciplinary team of experts. Audiology Unit: At SGH Dubai the Audiology Service run closely with its ENT colleagues covering all the aspects of hearing dysfunctioning. The Audiologist carries out a range of tests on adults and children to determine the presence, nature and extent of hearing loss and balance disorders, enabling accurate clinical diagnosis in a range of hearing related conditions. Laparoscopic Unit: Laparoscopic surgery has been one of the fastest growing areas in recent surgery. Committed to advancing minimally invasive surgery through education, research, surgical treatment, and fostering collaboration in endosurgical techniques across specialties, SGH Dubai laparoscopic unit provides patients with state-of-the-art endoscopic and laparoscopic procedures. SGHD is having a strong laparoscopic team for Obstetrics and Gynecology, General Surgery, Orthopedics and Urology and this make it as center of excellence. The unit successfully treating laparoscopic inguinal and ventral hernia repair, laparoscopic colon surgery, bariatric surgery, modern management of foregut diseases, and other minimally invasive procedures. Sports Injury Unit: At SGH Dubai Sports Medicine Unit our sports medicine doctors provide specialist clinical and diagnostic services and use innovative treatment interventions to optimize recovery from sports injury, prevent future injuries and improve sporting performance. Our specialists cover all aspects of sports injury including Achilles tendon, Tendinopathy, Running injuries, Stress fractures, Football injuries, Hamstring injuries, Low back pain. At SGHD a team of expertise provides all kinds of arthroscopic surgeries supported by a highly qualified team of physiotherapist. Hand and Shoulder Surgery Unit: The SGH Dubai Hand and Wrist Unit bring together world-class surgeons and therapists. The Unit has been providing expertise and high quality care for adults and children with conditions affecting the hand, wrist and elbow. Our team consists of the most distinguished Orthopedic with specific hand and wrist training providing the medical and surgical care, together with senior physiotherapists (PTs) providing the rehabilitation services. Dialysis and Renal Unit: The Dialysis Center at SGH Dubai provides patients with dialysis, a life-saving treatment, for patients with chronic kidney failure. The Dialysis Center is a hospital-based unit that has 8 dialysis stations. The unit provides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) treatments to a diverse group of adult patients who have chronic (long-term) kidney failure. Heart Center: To diagnose and treat cardiac conditions efficiently, SGH-Dubai offers the most comprehensive range of state-of-art diagnostic equipment and treatment tools including the catheterization laboratory and Cardiothoracic Surgery. It offers a multi-disciplinary approach for preventing the occurrence or progression of cardiovascular disease covering patients of all ages, making ours one of the leading Cardiology hospitals in Dubai. We provides a full range of non-invasive and invasive cardiac investigations/treatments including: 128-Slice CT Coronary Angiogram, Anti-Coagulation Clinic, Cardiac Rehabilitation, Chest Pain Triage, Coronary Angiography, Coronary, Angioplasty And Stenting, Exercise Stress Testing (TMT), Heart Failure Clinic Pacemaker & Defibrillator Implantation, Pediatric Cardiology and all other cardiology related diagnostic and procedures. Additional Cardiac Surgery at SGH Dubai started its state of art Cardio-Vascular Surgery Unit with a team of expertise

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MUNICIPAL COUNCIL OF SEBERANG PERAI Maimunah Mohd Sharif, President Municipal Council of Seberang Perai, Jalan Perda Utama, Bandar Perda, 14000, Bukit Mertajam, Penang, Malaysia phone: +006405497402 e-mail: [email protected] www.mpsp.go.my Penang State is located in the northern part of the Peninsular Malaysia within the equatorial region where it experiences warm and sunny weather together with plentiful rainfall, especially during the southwest monsoon from April to September. The State is geographically divided into two sections, Penang Island and a strip of land on the mainland which was earlier named Province Wellesley by the British and later changed to Seberang Perai. Seberang Perai which covers an area of 740 sq. km. is divided into three districts and has a total population of 818,200 persons. Most of its population is concentrated along the coastal and metropolitan areas especially in the northern and central parts of Seberang Perai. Major land uses in Seberang Perai are agriculture and residential followed by industry. On December 15, 1976, the territory received a Municipal Council status to be known as Municipal Council of Seberang Perai. Municipal Council of Seberang Perai is run by a management body whose members consist of the President and 24 Councilors who are nominated by the State Government. Six Council Committees are established to enforce existing policies and to make new policies. The Council Committees’ members are appointed by the President. The organizational structure is made up of 16 functional departments and headed by the Council Secretary. With an approximate area of 740 sq. km. under its jurisdiction, Municipal Council of Seberang Perai (MPSP) is one of the largest local authorities in Malaysia. MPSP is tasked with such a big responsibility in ensuring the cleanliness of Seberang Perai, enhancing the quality of its services delivered to the people as well as attract investment and tourism to the Seberang Perai District. In order to fulfill the high expectations of the customers and to meet the demands of its residents, MPSP came out with the Transformation Programme that moves towards making a drastic change in improving and enhancing the quality of life of the whole community residing in Seberang Perai. With the theme, ‘Sustainability Is Our Commitment’, MPSP engages the community in an effort to reduce the carbon footprint and to maintain the cleanliness in Seberang Perai. This is in line with the concept of Cleaner, Healthier and Safer Penang introduced by Penang State Government. MPSP has also set short term action plan which is known as ‘Focus’ for the organization on a yearly basis. The total achievement for Focus 2013 is 89.66% from 224 activities implemented within internal department of MPSP, which outlines in depth the focuses on clean environment, flood mitigation, community participation and well being, beautification and enhance the greenery, integrated enforcement, strengthening financial capability and capacity building. Based on these results, MPSP is intended to continue this effort in 2014. Nine focuses that will be emphasized on cleanliness, safety and traffic, law enforcement, flood mitigation, beautification, greenery and public facilities, community participation, capacity building, fiscal strengthening and work process efficiency. These focuses in place, it is hope that the MPSP will continue towards Penang State’s dream to be as the International and intelligent city. Besides, MPSP is currently putting an effort in developing a system called ‘Smart Monitoring System’. This system was introduced to improve on the quality of services to Seberang Perai residents especially on: flood monitoring and responding, earth works monitoring and enforcement, building monitoring and enforcement, illegal dumping and environmental issues, mode of monitoring.For all the efforts and passion, here are the achievements during last year 2013:• MPSP website was awarded 5 stars by the National Government• Penang Green Office (April 2013 – April 2015) By Penang State Green Council• Green Initiative Award by the National Government• Sustaining ISO Certificate awarded since 1999 until 2014 by SIRIM• Member of CITINET• Established Friendship City with GwangJu Metropolitan City Council

Private clinic SHAPAGAT Amanzhol Adayev, Chief Doctor 22, Shintasova Str, Kandyagash, Aktobe Region, 030700, Republic of Kazakhstan phone/fax: +7 713 333 60 22 + 7 713 333 65 98 e-mail: [email protected]

Private health ‘SHAPAGAT’ was reorganized in 1997 into private hospital in accordance with the legal normative act. It has both healthcare license and certificate of accreditation. It provides inpatient, primary health care and specialized outpatient care services to the population under the stat order. ‘SHAPAGAT’ has been a member of the international conference of WHO (World Health Organization) Health Promoting Hospitals HPH since 2003.

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SEMARANG MUNICIPALITY Hendrar Prihadi, Mayor Jl. Pemuda 148 Semarang 50132, Jawa Tengah, Indonesia phone: +62 24 3562421 e-mail: [email protected] www.semarangkota.go.id Semarang City is the Capital City of Central Java Province. It is located on the north coast of the island of Java, Indonesia with an area of 373.70 square kilometers (144.29 sq ml) which consists of 16 Districts and 177 Subdistricts with a population of approximately 2 million people, making it Indonesia’s sixth most populous city and the fifth largest Indonesian city after Jakarta, Surabaya, Bandung, and Medan. The location of Semarang City is very strategic; it is the hub of national transportation. It has Potential sea port, airport, railway network, and primary arterial roads that make it become a dynamic city. The year of 2013 had been proclaimed by The Government of Central Java Province as Visit Jateng Year. As The Capital of Central Java Province, Semarang City commits to support and success it by declaring a program Ayo Wisata ke Semarang (Let’s Have a Picnic to Semarang) as one promotion effort to raise tourism sector in Semarang. There are many tourists’ attractions in Semarang City such as Lawang Sewu (Thousand Doors), Masjid Agung jawa Tengah (Central Java Great Mousque), Sam Poo Kong, Blenduk Church, Pagoda Avalokiteswara.Semarang City is now leading by Honourable Mayor Hendrar Prihadi who has lead Semarang since October 2013 to July 2015 with the vision: ‘to make Semarang City as Trade and Service city which cultured towards the prosperous community’.

SPECIAL HOSPITAL FOR SURGICAL DISEASES FILLIP II Zan Mitrev, General Manager Bul. Ilinden 113, 001000 Skopje, Macedonia phone: +389 2 3091-500 fax: +389 2 3091-499 e-mail: [email protected] www.cardiosurgery.com.mk The Special Hospital for Surgical Diseases ‘Filip Vtori’ was established by Academician Zan Mitrev on 01.03.2000. From the very beginning of its existence, it is presenting a new and original concept in medicine based on modern medical technology, prime education of staff, intensive work and uncompromising dedication and humanity for patients.During the time, the hospital became top cardiovascular center with more than 1500 open heart surgeries and vascular surgeries at annual level, followed by adequate development of the mini invasive interventional procedures for treatment of congenital heart diseases. For 14 years existing more than 16 656 open heart surgeries had been done with 8235 by-pass, 1909 valvular, 725 aortic, 748congenital heart, 70tumors, 4772 abdominal aneurysms and peripheral vascular surgeries had been done. The hospital is highly specialized and known as the prime hospital for treatment of most severe cases of patients with ischemic heart disease, reconstructive surgery of the valvular diseases, dissections and thoracic-abdominal aneurysms, carotid surgery and treatment of terminal stage of limbic vascular disease with and without gangrene. This development of cardiovascular surgery is enabled with the continuous work of the supremely organized intensive care.The surgical hospital is characterized by development of the other operative branches; such are orthopedics, abdominal surgery, thoracic surgery and urology. Besides the eminent surgeons, the anesthesia care team provides security for success during every type of operative treatment.Exact and timely diagnostics based on modern imaging techniques provides right diagnosis at the right time for every patient.The medical professional team is always dedicated to scientific-research activity, promotion of the medical approach and continuous medical training. The development of the hospital is evident, and the realized statistics is the foundation for trust of the citizens! Following the medical development and needs of our patient from the beginning of the 2015y hospital will continue to exist in a new and high technique building.

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SOUNDARAPANDIAN BONE AND JOINT HOSPITAL AND RESEARCH INSTITUTE PRIVATE LIMITED Soundarapandian Sivamurugan, Director Aa-16, 3Rd Main Road, Anna Nagar, Chennai, Tamilnadu, 600 040, India phone: +09840074224 fax: +044 26213266 e-mail: [email protected] www.boneandjointindia.com

Soundarapandian bone and joint hospital is a 55 bedded hospital established in the year 1983 and since then has been involved in the treatment of orthopaedic and traumatology patients. The hospital is located in a prime locality in chennai, tamil nadu, india and about 25 kms from the chennai international airport.Prof. S.soundarapandian, the founder director of soundarapandian bone & joint hospital has enriched one and all with his rich knowledge and experience. His years of service in the madras medical college marks more than a decade. The founder director’s patient and untiring service in the hospital still continues which has helped the growth and solidarity of this renowned hospital.Dr. S. Sivamurugan, the director of our hospital has followed his esteemed father’s footsteps in the line of orthopaedics. After his primary training in orthopaedics in india had his higher training at the prestigious nuffield orthopaedic centre, oxford, u.k. his special interest are joint replacement and spine surgery. Dr. S. Ravi subramaniam, the director of our hospital has established a separate identity for himself in the line of arthroscopy. He is also trained in india and oxford and has special interest in arthroscopy and cruciate lligament reconstruction and shoulder surgeries. These able doctors are supported by a dedicated team of other doctors.The hospital is equipped with modern facilities for joint replacement surgery, arthroscopic surgery, spine surgery as well as trauma surgery The hospital has 4 exclusive state of the art operation theatres with c-arm image intensifiers. Use of special laminar air flow theatre has kept the infection rate comparable to western standards. We provide a comprehensive range of services that cover all aspects of high quality specialised orthopaedic care. Comprehensive medical and surgical management of patients afflicted with arthritis are provided by a team comprising of arthroscopic surgeon, joint replacement surgeon and rheumatologist. Joint replacement for all major joints is performed in an exclusive state of the art laminar air flow theatre. Advanced instrumentation for scoliosis and degenerative disorders of the spine are performed. Microdisectomy of the cervcal and lumbar spine are perfomed. The hospital is one of the pioneeing centres for acl reconstruction in india. The latest surgical technology for reocnstruction of knee, shoulder and ankle joints are available. Routine arthroscopic surgery is performed on an outpatient basis in our mini day care centre.Emergency trauma service is available round the clock enabling early and effective management of injured patients. We adapt the golden hour principle to treat trauma patients for which our paramedical stafff are well trained. The hospital is a referral centre for reconstructive surgery of complex fractures with 24 hours fracture treatment facility. The sports medicine service is complemented with a full-fledged brace clinic and also with specially trained physiotherapist. The hospital also runs some preventive health care programmes like the spinal rehab where a comprehensive programme that includes education and specific exercise programmes that helps prevent recurrent attacks of back pain. Well trained staff and latest technology help us to embrace our philosophy of providing the ultimate orthopaedic care to our patients. We have well trained nurses who are masters in assisting all the orthopaedic procedures. Every orthopaedic emergency as well as orthopaedic procedures are carried out by experts. International patient careOur international patient program gives complete support to patients and their accompanying family members. It offer the most comprehensive medical care and treatment. Soundarapandian bone and joint hospital makes patients feel at home by providing them with traslation services, appropriate cuisine and checks of their vaccination / immunization status before they arrive in india. We launched the whole body cryotherapy for the first time in india. Whole body cryotherapy is an invigorating treatment in which the body is exposed to -110 degree centigrade in order to encourage the natural healing process. The facililties available at the hospital backup the skills of the doctors and the dedication of the staff.

VODNYE RESURSY- MARKETING, LLP Orman Anarbek, Director General 17, G. Ormanov Street, 160013, Chimkent, Republic of Kazakhstan phone: +8-7252-32-11-94 fax: +8-7252-32-25-44 e-mail: [email protected] www.wrm.kz Water and wastewater services

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SUNGAI PETANI Honourable Datuk Haji Ismail bin Haji Said, President of Sungai Petani Municipal Council Sungai Petani Municipal Council, Patani Road, 08000 Sungai Petani, Kedah State, Malaysia phone: 6044296669 fax: 6044296655 e-mail: [email protected] www. mpspk.gov.my Sungai Petani was opened in 1912, and officiated in 1915, by George Maxwell, the first British Adviser to Kedah. Now, it is the largest town in the state of Kedah, Malaysia. It is under the sultanate of The Sultan of Kedah, His Royal Highness Al-Sultan Almu’tasimu Billahi Muhibbuddin Tuanku Alhaj Abdul Halim Mu’adzam Shah Ibni Al-Marhum Sultan Badlishah, and under the administration of The Chief Minister of Kedah, His Excellency Dato’ Seri Haji Mukhriz bin Tun Mahathir.The population of the district is almost 500,000 comprising of a majority of Malays, secondly Chinese and the rest Indians and also Siamese. Sungai Petani is unique in the sense that one can live comfortably with the modest cost of living but with modern living standards and yet experience country life. Sungai Petani Municipal Council provides all municipal service within its jurisdiction for 9 sub-districts and 13 towns in the District of Kuala Muda. Sungai Petani is a fast moving town in terms of development especially in the economic sector. There are 1335 industrial buildings and 13714 commercial buildings. There are more than 20 hotels. A government hospital, four private hospitals, and numerous clinics and pharmacies cater for the residents’ medical needs. The infra structure in Sungai Petani is modern and up to date. The modern road system provides a jam free traffic and no hustle bustle of city life. Place to visit in Sungai Petani: - Bujang Valley, one of the oldest settlements in the world, a major archeo-tourism attraction- Mangrove Forests at Semeling, having among the most number of mangrove species in the world- Tanjung Dawai, a fishing village known as a seafood spot in Sungai Petani. - Tupah Recreational Forest, a popular picnic spot, with its natural cooling waterfalls, a wide range of plant species - Gunung Jerai (Kedah Peak), a limestone peak near Sungai Petani, one of the most conspicuous peaks in Kedah, 1380m (4140ft) tall.- Merdeka Beach, the perfect destination for one to relax and enjoy the sea breeze.

SWISS BIOSTADT LIMITED Emmanuel Ajayi, Chief Executive Officer 387 Agege Motor Road, Cappa, Lagos State, Nigeria phone: +234 8034004481 e-mail: [email protected], [email protected] www.biostadtgroup.com Biostadt is a Lifescience Company. It started business in Nigeria in 1964 as CIBA – GEIGY and metamorphosed to SWISS BIOSTADT LIMITED in 2010. It was formed out of the need to contribute to the fight against hunger, malnutrition and disease burdens in Nigeria in particular and the entire Africa Continent as the nation and continent continue to witness high mortality and morbidity coupled with negative impacts on human capital from above factors. The Company currently carries out businesses in Nigeria, Ghana, Liberia and Sierra Leone and has plans to expand to other West and Central Africa Countries. In Nigeria which is the major hub, it is headquartered in Lagos on a sprawling 2.83 acres of land built into state-of-the art offices and laboratories. To meet the above objectives, the Biostadt Company consciously entered into business partnership with multinational companies that are designing players in the area of health care, pharmacy and agriculture.The Biostadt Company carries out its businesses in line with the Company’s Code of Conduct and Health, Safety, Environment & Quality (HSE & Q) Policy in the strictest terms. Moral and ethical standards guide the company in its day to day business dynamics with a clear view for professionalism and profitability within the legal and regulatory frameworks. At all times, the Biostadt Company will satisfy its teaming stakeholders – Customers, Staff and Shareholders – through aggressive value addition activities and solutions. As a responsible corporate citizen, the Biostadt Company organizes an annual week of Corporate Social Responsibility events. In some years, the activities were on tree planting. This is meant to fight desertification apart from improving the carbon dioxide versus oxygen ratio in the atmosphere; both are critical ingredients for man and plants. In others, we supported 150 VVF patients and motherless babies’ homes. They were equally provided with the tools they need free of charge.

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SWISS HEALTH Baarerstrasse 112, P.O. Box 2428, CH-6302 Zug, Switzerland phone: +41 58 252 51 51 fax: +41 58 252 51 99 e-mail: [email protected] www.swisshealth.ch Switzerland – Excellence in medicine and hospitalitySwiss Health is the representative for leading Swiss hospitals and clinics which are committed to providing maximum treatment and care to international patients. The quality of high-end Swiss medical care together with its state-of-the-art medical infrastructure forms the foundation for an internationally outstanding performance record. As a whole, the hospitals and clinics recommended by Swiss Health cover the complete range of disease patterns. Swiss Health aims to provide patients and their referring physicians with a choice of the most suitable hospitals, clinics and outpatient centres. Swiss Health is in line with the long tradition of Switzerland’s excellent health care system. When it comes to health and quality of life, only the best is good enough.Why medical treatments in Switzerland?

- First class medicine - Medical research on the top- Experience and education - Quality and tradition - Hospitality and outstanding customer service - State of the art infrastructure - Switzerland – that’s stability and safety!

Key Areas of medical specialization / USP’s of Swiss Medicine.- Pediatrics- Orthopedics, incl. sports injuries - Cardiology- Treatment of spinal cord injuries - Oncology- Obstetrics / Gynecology- Opthalmology/ENT- Rehabilitation and prevention- Sports Medicine- Urology- Medical Check-Ups

UKRAINIAN ASSOCIATION OF MANUAL THERAPY Nikolai Nasikovskyy, President ap.62, 18a Blv. Verkhovnoi Rady, 02100, Kiev, Ukraine 64, 159 Sadovaya str., Osokorky st., Kiev, Ukraine phone: +38 0442229145, +38 044 4677956 mobile: +38 0677129317, +38 095864-2147 e-mails: [email protected], [email protected] www.narod-manual.org.ua Ukrainian Association of Manual Therapy was established on April, 2006. The organization conducts workshops at which more than 1,500 peoplebecame skilled at Old Slavonic massage. Old Slavonic massage is one of the most ancient alternative treatment methods. It has no analogues in the world practice. The essence of this method is to press down viscera by hands through the front abdomen wall to remove stagnant processes. With a proper and competent performance this simple action helps to achieve great results: to eliminate venous and lymphatic congestion, to relieve spasms of viscera, to restore the position of viscera. The mechanism of this method is very simple. While pressing down the weakened muscles in the body, we are working not only on a viscus itself, but also on surrounding tissues. Thereby blood circulation improves, metabolism increases. And as a result tissues are compressed and then extended again. The pulsation starts in body cells and congestion eliminates effectively. Workshops were held in Russia, Ukraine, England, USA, Czech Republic, Spain and Germany. Different people have become experts in the field of Old Slavonic massage: economists, accountants, housewives, actors, athletes, workers of tourism industry, as well as medical professionals of different specializations and grades. Association had been holding 7 international conferences, which gave a strong jolt for the development of traditional medicine in Ukraine. The President of Ukrainian Association of Manual Therapyis Nikolai Nasikovskyy, Academician of Russian Academy of Manual Therapy, Board Member of Russian Association of Visceral Therapists, Council Member of Ukrainian Healing Academy, Master of Folk Medicine.

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TI SANA DETOX RETREAT & SPA Erica D’Angelo, Owner and General Manager Via Fontana, 5, 23885, Calco, Italy phone: +390399920979 mobile: +393475014866 e-mail: [email protected] www.1711.it, www.tisanadetoxretreat.com Wanting to live at optimum weight, improve aging and reduce risk of various diseases? Become a Healtheatarian!Optimize your energy levels, enjoy greater vitality and a better quality of life, reduce the risk of cancer, cardiovascular and degenerative diseases with Ti Sana’s new Healtheatarian Active Life programme designed to help you learn to set up and manage your own lifestyle. Ti Sana Spa & Detox Retreat located outside Milan has designed a brand new health programme which includes a scientific-based nutrition combined with medical Spa treatments and gentle activities, guaranteed to give you the results you desire or your money back! According to Ti Sana, being a Healtheatarian is optimizing one’s energy and using it to heal our body and mind. Taking the first step can be hard, that is why the Healtheatarian Active Life programme is designed to give you the kick start you need! Over the course of 10 days, you will be given a tailor-made, scientifically-based nutritional programme combining raw and cooked plant-based ingredients with a gourmet touch to inspire and treat your body in a holistic way. The activity programme is tailored to revitalise and re-energise you and includes a variety of medical Spa treatments including a Bioimpedance test, body therapies such as Dead Sea mud wrap, Draining facial Massage and infrared sauna, and physical activities programme including power walking, fitness and yoga amongst others. Make use of extra activities such as cooking lessons, Ayurvedic presentations, and lectures on creating your personal nutritional plan to boost your knowledge of maintaining your own health & wellbeing. Ti Sana Spa & Detox Retreatis an 18th century dwelling in the Lombardy region of Italy. It has been restored and revived by the D’Angelo family and become an award winning retreat and Spa for those who are serious about their wellbeing. Incorporating holistic therapies, gentle and therapeutic physical activity and nurturing nutrition, Ti Sana offers you to chance to listen to your body’s natural signals amidst an enchanting local environment.

UNION NATIONAL BANK

Mohammad Nasr Abdeen, CEO Abu Dhabi, UNB Building, Salam Street, P. O. Box 3865, UAE phone: +972-674 1600 fax: +972-678 6080 www.unb.ae

Union National Bank (UNB) is a public joint stock company incorporated under the laws of the United Arab Emirates in 1982. UNB is the only bank in the UAE with significant shareholdings by the Governments of both Abu Dhabi (50%) and Dubai (10%). The remaining 40% of the shares are publicly held. The shares of UNB are listed on Abu Dhabi Securities Exchange.UNB operates through a wide network of branches and ATMs throughout the UAE. UNB has extended its reach to Egypt through a successful acquisition of the erstwhile ACMB and currently operates in the country as UNB Egypt through a number of banking centres. It has ventured into Doha with a branch at the Qatar Financial Centre and has also opened a representative office in Shanghai China, being the first bank from the region to do so. Following approvals, UNB’s Kuwait Branch has been opened with a soft launch and is operational since Oct 2012.UNB’s subsidiaries include, Union Brokerage Company (UBC) which provides brokerage services for clients at the Abu Dhabi Securities Exchange and the Dubai Financial Market, Al Wifaq Finance Company (AWFC) offering Shari’a compliant products and services to the growing Islamic banking market and INJAZ Marketing Management which provides marketing management related services, including the planning, execution and marketing of products and services for UNB through a dedicated team of professional sales and marketing representativesIn its quest for excellence, UNB has adopted the Total Quality Management concepts and systems and business excellence framework. In the process it has received several prestigious accolades and third party validations. As part of its CSR strategy UNB has embarked on an ambitious Sustainability drive within the organization. The inaugural 2011 UNB Sustainability Report was rated ‘A+’ by the Global Reporting Initiative (GRI), making it one of the first Banks in the region to achieve this distinction.In the months and years ahead UNB is fully prepared to scale new peaks of excellence and performance under the guidance of its Chairman HH Sheikh Nahayan Mabarak Al Nahayan, UAE Minister for Higher Education & Scientific Research and the visionary leadership team of UNB led by CEO Mr Mohammad Nasr Abdeen. To find out more about Union National Bank and its products & services, log on to www.unb.ae, call 600-566-665 or visit a conveniently located branch in your vicinity.

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INTERNATIONAL MEDICAL CENTER MMC ODA Kravchik Maximilian, Head of the Department Neurosurgery Universitetsky prospect, 6 Moskow, 119333, Russian Federation phone: +1(499) 137-07-33, (499) 727-04-78, (499) 343 77 07 e-mail: [email protected] www.mmc-oda.ru

‘MMC ODA’ - International Medical Center of treating the most serious pathology - was originally designed to attract the Russian Federation highly qualified doctors with extensive experience from Germany, USA, Israel, Switzerland and other foreign countries in order to create alternative of the ‘medical tourism’ in the developed European countries, as well as attracting foreign patients to Russia from abroad. This is one of the few centers in Moscow, which have official permission for foreign specialists. ‘MMC ODA’ can get a medical examination and treatment of the European level of quality, while prices for medical services by 25-30 per cent lower than in Europe. ‘MMC ODA’ is equipped with modern medical equipment, excelling in technological most Russian and foreign hospitals. Many of the medical procedures that are protected by international patents and practiced in our center, no used in any medical centres in the Russian Federation. ‘MMC ODA’ this is the only medical clinic in the Russian Federation, which has a certificate of quality Swiss Institute of Standards (‘SIQS’), as well as awarded the international prize ‘European Quality’ and the International Prize ‘Best Enterprise’ - for high quality and compliance with international standards of treatment. The specialists of ‘MMC ODA’ are owners of the diamond branch of the ‘Manager of the Year’, and ‘International Socrates Award’ winner in 2013 ‘MMC ODA’ received a certificate WTO and National Institute of Standards and Technology

BAGHDAD PHARMACY COLLEGE Abdulmuttaleb Abdul Ghani Naser, Assist., Prof., Ph.D in Pharmacy, Dean Bab Al-Muadam, Baghdad Medical City Center Baghdad, Iraq phone: +9647801610185 e-mail: [email protected] www.bpc.edu.iq

On 14th Sept. 2000 the Ministry of Higher Education and Scientific Research issued its agreement, due to provisions of article (38) of the private universities and colleges law numbered (13) of the year 1996. The college is private institution of public interest and of significantly and of financial and administration independent.The college has its on resources from the student fees and from serves to the pharmacy industry. The college now owns 3 pieces of land in a busy street near the Medical City which is used for training of our student to build its on buildings. The land mentioned which is about 1500m2 needs to build multistory building. In the future we prepared to open our Human Medical College, and ask investors to build a hospital of 400 beds.The college is not owned to private sector but it was established by syndicate of pharmacist to serve the Iraqi community and it has independent administrative and financially.The college of Medicine still needs the agreement of Ministry of Higher education, it needs investment in 400 beds to be an educational and training hospital to the university and give services to community. We ask investor to study our intention to build a hospital with 400 beds to be used commercially and for the University purposes.

BUREAU D’ETUDES DU BÂTIMENT ET DES TRAVAUX PUBLICS

Jérôme Buya - Director General B.P. 1129, Brazzaville, Congo phone: +242 055511253 e-mail: [email protected] www.bebatp.com

Created in 1986, the Bureau of Studies and Public Works Building, abbreviated ‘BEBATP’, urban planning company in the Republic of Congo. Area of interest - urban planning, architecture, engineering, construction and public works.

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APOLLONIA UNIVERSITY OF IASI Vasile Burlui, Prof., PhD, President Muzicii Street, No.2, Iasi, Romania phone: +40232 210 310 fax: +40232 210 310 e-mail: [email protected] www.univapollonia.ro Àpollonia` University as an institution of higher education and Scientific research that operates under the Romanian Constitution and legislation in education is working in full autonomy and academic freedom and operates under responsibility and public liability for the education offered. The mission that Àpollonia` University assumes as sized on three main areas: culture, education and formative. Through cultural component, the university is committed to promote science in the spirit of democracy, academic freedom and integration in the international scientific community. Education department engages university through its structural components (Faculty of Medical Dentistry contains Medical Dentistry, Dental Technique, Balneophysiokinetotherapy and Recovery, General Nursing study programs and Faculty of Communication Science consists Journalism, Communication and Public Relations study programmes). The University also provides 2 research institutes (Ìoan Haulica` and Modern Languages Institute). Apollonia University offers a practical training platform and a clinical training platform. All these structural components provide academic facilities in order to satisfy a wide range of educational requirements. Formative side insists on creating elite specialists, active citizens, responsible and tolerant, to the quality of the knowledge-based society, culture and continuing education.Apollonia University was founded in February 1990, going through several steps in accordance with law 88/1990 on accreditation of higher education institution.-In 1990-1991 school years, according to the law 54/1990 and the approval of the Ministry of National Education, no.82799/18 July 1990, in the Apollonia University of Iasi began operating the Faculty of Medical Dentistry, University College af Dental Technology and University College of nurses.-By Law 481 of 11 July 2002 was accredited the Faculty of Medical Dentistry – dental studies program; institutional accreditation.-By G.D. no. 966 of 29 September 2011 it is settled the structure of Faculty of Medical Dentistry: Medical Dentistry, Dental Technique, General Nursing, Balneokinetotherapy, Balneophysiokinetotherapy and Recovery and the Faculty of Communication Sciences including Communication and Public Relations, Journalism.Apollonia Universities shares `The Lima Declaration on Academic Freedom and Autonomy of Institutions of Higher education`(1988), `The Magna Charta of European Universities` (Bologna, 1988) and ‘Academic Freedom and University Autonomy’ (Sinaia,1992) and adhere to university organizations that recognize these documents.

IRAQI CENTRE FOR CANCER AND MEDICAL GENETICS RESEARCH Nahi Yaseen, Dr., Prof. Director General Qadissiya Q, Sec 604, St 23, Baghdad, Iraq phone: +9647901475964 e-mail: [email protected] www.iccmgr.org The Center was established by the effort of Dr. Nahi Yousif Yasseen as a first research centre that deals with cancer and genetic diseases in Iraq. It was built during very difficult conditions surrounding Iraq. However, this Centre has been able to establish a very strong basis for cancer and genetic research and offer new diagnostic, medical and clinical services for all Iraqi population. It is the only Iraqi Scientific Centre which offers cytogenetic and chromosomal studies for cancer and genetic diseases. The Centre was able to establish Iraqi cancer cell lines and graduated many postgraduate students in the field of cancer and genetic diseases. It is the only Iraqi centre which can give specific diagnostic, medical and clinical services for all Iraqi people. Patients from all Iraqi cities, towns and villages can visit the Centre to get their requirements for medical purposes. Therefore this Centre provides unique and great services for people, most of services are free while some are done by cheap fees in order to support the health system in Iraq. The Centre directly or indirectly develops research level in Iraq and offers new services for all people.These activities will support the development process in the country. In Iraq all Research centres work under the umbrella of the government, therefore all Center’s activities will go through governmental benefit. Almost all the Centre programmes are designed for the social benefit either for diagnostic or medical services. Most research projects deal with Iraqi population such as environmental pollution impact, cancer incidences, genetic malformation, abortions and sterility etc. Every year the Centre Council puts a scientific plan for new research project and for offering better services for people. The forthcoming plan is to build specialized hospital, establish educational institute and to establish many specialized clinics in many cities.

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CIVIL ENGINEERING CONSTRUCTION CORPORATION No.4 Mr. Le Ngoc Hoa, Master of Construction Econocmics, General Director No. 243A De La Thanh Str., Hanoi, 10000, Vietnam phone: +84436420371 fax: +84436811275 e-mail: [email protected] www.cienco4.vn Established in 1962, with 50 - years development and growth, with the human resources of more than eight thousands engineers and staffs, 23 subsidiaries, thank to the creative and dynamic efforts of all leaders and staffs, Civil Engineering Construction Corporation No.4 (CIENCO 4) have a sustainable development in all activities; have become the leading unit in civil engineering construction field and has been gradually developing into a powerful economic corporation in Vietnam.Fields of operating:- Construction of domestic and abroad civil engineering ;- Construction of industrial, civil works;- Construction of drainage infrastructure, filling the background, lighting;- Fabrication of steel bridge girders, structural steel, mechanical products;- Investment in transport infrastructure, other infrastructure projects under BOT or BT;- Survey and design of transport, civil, and infrastructure works;- Consulting on investment and construction of traffic, civil and infrastructure works;- Testing of construction materials, Testing and verifying the quality of Civil engineering and works under other branches;- Commercial business, export of goods, supplies and equipment.Considering science and technology as a key breakthrough, CIENCO4 currently has owned many modern and advanced road and bridge construction technologies, and constantly co-operate, do research and get access to new technologies. We are now competent enough to carry out high quality required constructions such as cable-stayed bridge, the tunnel, airports and harbors.Cienco 4 has completed and handed over several key transportation projects across the country: Da Rang Bridge Construction, Flood protection package FL2, Nam Dinh S2 package,the bridges of Son La hydropower project, Ho Chi Minh Highway Construction, Bridges of N2 Route, Ho Chi Minh – Trung Luong Expressway Construction, Vinh Tuy Bridge Construction, Ben thuy Bridge no.2, Vung Ang Port Construction, National highway No.54, Thieng Duc Bridge Construction, Ham Luong Bridge Construction, Thu Bien Bridge Construction, Pa Uon Bridge Construction, Phung Bridge Construction, Cau Gie – Ninh Binh Expressway, Phu bai International Airport in Thua Thien Hue Province, Vinh Airport in Nghe An province, Da Khai hyroelectric Plant Construction (activating in January/2010). In addition, we have co-operated with foreign contractors in the following projects : Thanh Tri Bridge, Nhat Tan bridge, Hanoi - Hai Phong Expressway, Hanoi - Lao Cai Expressway. Due to effective methods in constructing management, our projects met or early finished before deadline, ensuring quality and are highly appreciated by investors.From early 2013 until now, Cienco 4 were rewarded and commenced many large projects with a total cost of in the tens of millions of dollars from the ODA of World Bank (WB) and JICA funds (Japan). Typically such as: Nguyen Tri Phuong Bridge Construction Project in Danang city, Co Co - Hoa Phuoc bridge Construction project in Da nang city; Hanoi City Ring Road Construction Project; road from Noi Bai airport to Nhat Tan Bridge.After a long time with effort and self-improvement, in August 2012, Cienco 4 has achieved certificate of quality management system ISO 9001-2008 by DNV Group (Norway). From 2002 until now, Cienco 4 has constantly received Vietnamese Quality Annual Award. In 2012, CIENCO4 was awarded the International Gold Star for Quality by Business Initiative Directions (BID). And in 2013, Cienco 4 continues to be awarded the 2013 Platinum Star for Quality, also by BID.With the tradition of ‘Drinking water, remember its source’ and concentrating on green development, Cienco 4 always focused on charity activities and policies, as well as environmental preservation. Every year CIENCO4 spends about 30% of profits to charitable and social contributions. Besides, we develop green environment with the aim of 40,000 planted trees along the routes each year. CIENCO4 is raising ‘Green Vietnam’ fund with national scale with the goal of environmental protection. CIENCO4 also gives preference to use clean technologies with the less environmental effects.Together with outstanding achievements of CIENCO4, our divisions and individuals have been awarded many noble medals by the Party and the State, including Ho Chi Minh Medal, an Independent Medal, Hero of Labor and Hero of Labor force.With the trend of international integration, CIENCO4 also expanded its co-operation. We have associated with South Korea and Japan to implement the projects. Do search, expand the market to neighboring countries as well as call for international capital. And in fact, our efforts have been recognized and highly appreciated by the international partners with the prestigious International Award.Our stability and development originated from oriented policies and steps. We constantly invest and develop science and technology together with the development of human resources and a harmonious combination of benefits. Moreover, we also diversify operating fields, enhance all competition criteria, respect the cultural and spiritual values, integrate with the international economy in which there is always Cienco 4’s prestige and brand.

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LLP ‘MEAT PROCESSING PLANT BIZHAN’ Khadisha Bizhan, Director General 52 ‘B’, Dulatova Str, Almaty, 050037, Republic of Kazakhstan phone: +7 727 384 55 95 fax: +7 727 384 51 28 e-mail: [email protected] www.bizhan.kz Khadisha Nurtaykyzy, General Director of ‘Meat Processing Plant Bizhan’, graduated from Semipalatinsk Institute of Technology in 1978 under a specialty of an engineer-technologist of meat and meat products processing. She has come a long way from ordinary technologist to a senior manager at various enterprises of the food and meat industry. In 1998 she founded her own company named ‘Bizhan’ for production of sausage and meat products in the city of Almaty.Now LLP ‘Meat Processing Plant BIZHAN’ is one of the largest domestic meat processing plants engaged in the production of sausages and specialty meats. The product range includes more than 80 brands of high quality Sausages and Kazakh national products made of horseflesh, with its own proprietary network in the cities of Almaty and Astana. In 2011, the company built a new modern slaughterhouse with the capacity of 70 heads of cattle and horses per a shift under the ‘Halal’ standard (Akmola region, Kokshetau).The company ranks among the twenty leading meat processing plants. The company uses high-tech European equipment that meets international standards. The company’s quality management system was certified under ISO 9001-2009 and food safety management system was certified under ISO 22000-2006.Excellent taste of Bizhan products is ensured through the use of ecologically-clean raw materials supplied from the northern regions of Kazakhstan.

GHANA NATIONAL GAS COMPANY George Sipa-Adjah Yankey, Chief Executive Officer P.O Box CT 3686, Cantonment – Accra, Ghana phone: 233(0) 302 744 200 fax: 233 (0) 302 744229 e-mail: [email protected] www.ghanagas.com.gh Ghana Gas is a mid-stream gas business company so incorporated in July 2011 with the responsibility to build, own and operate infrastructure required for the gathering, processing, transporting and marketing of natural gas resources in the country. The company will accelerate the nation’s effort of rapid industrialization by providing cost competitive natural gas and gas based products for domestic markets including the development of petrochemical industries, fertilizer and power generation, as well as export markets. The company’s core mandate is to process, transport, market and sell natural gas and Natural Gas Liquids (NGLs) produced in Ghana. The company will be operated on a business model which will primarily obtain revenue through processing, transportation, the sale of Natural Gas and NGLs.Mission: To contribute to Ghana’s rapid industrialization process by building the infrastructure required for gathering, processing and delivery of natural gas resources to industry in a safe, cost effective, responsible and reliable manner.Vision: To be a fully integrated gas business company with a strong reputation as a trusted partner and reliable supplier of natural gas resources in Ghana and abroad.As a company, we are progressively developing people centred and an environmentally responsible brand, whilst committed to providing exceptional client service and to living our core values:• Integrity- Honesty and Accountability in every aspect of our business;• Professionalism- Achieving challenging goals by being proactive and innovative;• Excellence- Deploying the best technology and management methods for achieving our objectives;• Team work- Cohesiveness and united in purpose;• Respect- Respect for people and fairness in our interactions;• Environment- Causing no harm to people and the environment;• Loyalty- Loyal to Ghana’s economic aspirations and the Company• Accountability- We are accountable for all our actions.

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PECULIARITIES OF CREATION AND DEVELOPMENT OF MEDICAL TOURISM IN TAJIKISTAN Autor: Muazzam Ansorov Rector of Tajik Pedagogic Institute in the city of Penjikent, Republic of Tajikistan

During the last years one of tourist branches caused by the process of globalization that gives the possibility to combine medical treatment and relaxing abroad became the branch called medical tourism. During their trips patients can receive professional medical help at different medical centers.What about investments in such branch of tourism they are constantly growing. The global market of medical service has already been created and now it is permanently developing.Creation of medical tourism and its development is being influenced with the infrastructure and a number of other factors of social and economic origin where the main point is the existence of the infrastructure of the world standard and highly qualified staff. At the same time creation of the infrastructure of the world standard as well as highly qualified staff demands investments. That is why it is logically explained that at first medical tourism appeared in highly developed countries. These countries are Germany, Switzerland, France and Austria. In the USA, Canada and Israel medicine has always been developed and continues to be on its highest level.Some Asian countries (Malaysia, Thailand, Singapore, Hong-Kong, Turkey, India, Southern Korea), some countries of Eastern Europe(Poland, Czech Republic,

Hungary), some ones of Southern and Central America (Costa-Rica, Mexico, Brazil, Cuba), Near East (United Arabic Emirates) are constantly approaching to the level of leading countries.Not high social and economic standards of the population of Tajikistan, their low purchasing capacities are one of the reasons why medical tourism in Tajik republic is only at its point of start.Meanwhile during the last several years some medical centers with the latest equipment (Avicenna, Shifo) where highly qualified specialists who rose their qualification in some leading clinics of Russia, Germany, Japan, Israel, Southern Korea Iran work have already been created. In cooperation with specialists of upper mentioned centers different complicated operations are being held. We should also mention that unfortunately because of low purchasing capacity a numerous number of local population can not afford themselves to be treated at these centers.What about the entrance tourism it is poorly developed. Such situation can be explained that both private and state medical establishments are not known abroad and do not play any significant role in earning currency.In contrast to other Asiatic republics of the former USSR Tajikistan possesses huge recreational recourses where the most important of them are waters, mud lakes and natural climatic conditions.In the 30s of the 20 century famous balneologists of the USSR investigated mineral springs such as Khoja-obi-Garm, Obi-Garm, Garm Chashma, Khavotag, Shambary and 50 other springs in various natural climatic zones of the republic

especially in the Pamir region and nowadays some holiday resorts work there.Highly mountainous resort Khoja-obi-Garm is located at the height of 1087 m.and has been working since 1939 being the largest balneological resort of the republic.(more then 500 beds).Siliceous, high termal sulfate-bicarbonate-sodium waters with total mineralization of 0,5-0,6 g are about 93 C.One of the main peculiarities of the resort is a radon steam and extra hot mineral waters.Balneological resort Shambary is located 28 km, west to the capital of Dushanbe at the height of 1003-1150 m.above the sea level. The water of Shambary is sulphate-chloride-sodium with mineralization of 2,9 - 9,4 and sometimes up to 17,4 g. with the temperature of 22,5 – 38 C.Thermal waters of Shambary are widely used for treatment of the digestive system, functional disorder of the nervous system as well as gynecological one. Balneological resort Obi-Garm is 100 km from Dushanbe at the height of 1200-1800 m.


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The water there is chloride-sulphate-calcium-sodium with mineralization of 0,5-17 g and of 40-50C.It is used for treatment of such diseases as digestive system diseases, skin ones, of locomotors system ones and for drinking. Balneological resort Garm-Cashma is located in Pamir at the height of 2770m, 50 km from the centre of the autonomous region Khoroga. The water here is hydro-carbonate-sodium with mineralization of 3,3-3,5 g and of temperature from 36 to 68 C. Undeground waters contain 230-245 silicic acid and active microelements-iron, magnesium, strontium and others which give the water its balneological power.Combination of clarity and ionization of air, maximum amount of sunny days all year round and great concentration of ultraviolet rays effectively treats diseases of digestive system, of nervous one, of locomotors system and gynecological one too. In the north of Tajikistan there are balneological sanatoriums called Havatag, Zumrad and the unique climatic resort Istavtashan.Sanatorium Havatag is located 90 km from the town of Hojent at the height of 600m. The spring Havatag is of chloride-sodium type with mineralization of 4,4g. Weakly alkaline, silicic water is of temperature from 27 to 41 C.Besides its main elements the water contains bromine, iodine, iron, molybdenum, fluorine, lead, zine and others which make this water valuable for many groups of diseases.Sanatorium Zumrad is located at the height of 900 m, 3 km from the town of Isphara and is the one for 500 beds.Cardiological diseases, the ones of locomotors system, of periferic nervous system, metabolism are treated in it.The only in Tajikistan climatic resort Istavrashan for treatment of cardiological diseases is located 6 km from the town of Istavrashan and is 84 km from Khujand at the height of 1004 m.The resort is located on the northern slopes of Turkistan mountain range in favorable temperature and climatic conditions. Attractive nature, comfortable temperature, clean air, long amount of sunny days are good for heliotherapy, aero therapy on this resort where the main methods of treatment are good for cardiology.So, our brief review of modern medical tourism shows that despite a large amount of hot and cold springs, muds ,climatic resources, beautiful nature, comfortable temperature, clean air this branch of tourism only begins to develop.Dozens of places with hot and cold springs make a potential for creation and development of medical tourism and recreation. Unfortunately modern level of social and economic development of Tajikistan can not allow using completely all its recourses and needs investitions.In times of globalization foreign investors together with local ones could do this.


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S o c r a t e s a l m a n a c ‘ H e a l t h a n d W e l l n e s s t o u r i s m ’S o c r a t e s a l m a n a c ‘ H e a l t h a n d W e l l n e s s t o u r i s m ’

SOCIAL, ENVIRONMENTAL AND SOCIO-POLITICAL FACTORS OF ACTIVE LONGEVITY

President of the Russian Association of Gerontologists and Geriatrists,

D.Sc., Professor, Academician of the Russian Academy of Sciences, honoured worker of science of the Russian Federation

Professor Shabalin started his career in 1962 as a doctor of Omsukchansky regional hospital of the Magadan Region. From 1965 to 1975, he held various scientific posts of the Leningrad Scientific Research Institute of Hematology and Blood Transfusion. From 1975 to 1985 he was the director of the Institute. From 1985 to 1992 Prof. Shabalin was the Head of the Main scientific department of the RF Ministry of Public Health. From 1993 to 1997 he was the deputy minister of the RF Ministry of Public Health. From 1997 to 2013 he was the Director of the Russian Clinical Centre for Gerontology of the Russian Public Health Ministry. Since 2013 till present Professor Shabalin has been the Head of the Gerontology and Geriatry Department of the Russian National Research Medical University named after N.I. Pirogov.

Professor Shabalin is the author of 670 scientific works, 9 monographs, holds 72 patents for inventions, as an academic advisor he supervised 25 doctoral and 32 master’s theses.

by Prof. V.N. Shabalin, Prof. V.A. Grachev

President of the V. Vernadsky Nongovernmental Ecological Foundation, Russia;

D.Sc., Professor, Corr. Member of the Russian Academy of Sciences

Prof. Grachev started his career in 1960s as an engineer, then as a lecturer at the Penza State Polytechnical Institute. In 1990 he was elected a People’s Deputy, Deputy Chairman of the Committee on Science, Higher Education and Training at the Supreme Council of the Russian Federation. In 1993 - 1999 V. Grachev was the Head of Staff of the Federation Council Committee on Science, Culture, Education, Health and Ecology. In 1997 – 2007 he was elected a deputy of the State Duma, the Chairman of the Committee on Ecology. Prof. Grachev is an honorary member of the PACE. Since 2011 he has been the President of the Vernadsky Nongovernmental Ecological Foundation.

Prof. Grachev is the author of 243 inventions, 625 published works, 29 monographs, 10 textbooks, 15 manuals.

The most important demographic phenomenon at the turn of the 20th and 21st centuries was a global increase in life expectancy and, as a consequence, an adequate increase in the proportion of older people in the general population of the world. The growth rate of the elderly population is far ahead of the growth rate of the total population. At the same time, the older the age group, the more intense its population is growing. Dramatic aging of the population

is a major social problem that has a signifi cant impact on the economic, industrial and social relations of the present-day world. Importance of demographic aging is so great that the UN puts it on a par with the problem of preserving peace in the world.

Diversity of processes, aff ecting the aging of the human body, requires formation of a complex state and international measures

Vladimir A. Grachev Professor

Vladimir N. Shabalin Professor

to prevent the disease of aging, measures to ensure compliance with the dynamic adaptive capacity of the human body with natural and anthropogenic environmental changes.

Throughout the human history, there are many examples of longevity. It is known for the fact that there were people being up to 120-122 years

old. Women live longer than men. Jeanne Louise Calment lived 122 years. This Frenchwoman lived the longest life of all people. The oldest man is 118 years old. Apparently, these are the limits of human life.

Important facts are not only isolated cases of longevity, but also the general increase in life expectancy (Figure 1.).

Figure 1. Life expectancy of people

It is important to note as well that the important thing is not HOW MUCH, and HOW to live your life. There are many examples of active aging: the famous Russian actor V.M. Zeldin at his 99 continues to perform on stage. Well back in the early 30-ies of the last century he became famous for his roles in the movies (almost 85 years ago). Artist Boris Yefi mov lived 106 years, 103 years of which he regularly went to work. Shigechiyo Izumi of Japan lived longer than all men in the world - 120 years. His job seniority is 98 years.

No biological diff erences among centenarians have been found. They diff er in moderation in everything, calm character, sociability and love for their neighbours. Whereas their main feature is a permanent intellectual and physical LABOUR.

Most importantly is that one must make your brain work continually. Studies have shown that actively working with the brains makes it possible to off set the inevitable dying nerve cells well into a great

age, thus increasing the working quality of the remaining nerve cells. Here are the most obvious examples, showing that old age can be as fruitful as the youth. Sophocles wrote a brilliant tragedy “Oedipus” when he turned 100 years old. Leo Tolstoy, Voltaire, Goethe, George Bernard Shaw continued to create literary masterpieces at the age of eighty years and older. Ilya Repin, Ivan Aivazovsky created the best canvases at 80 - 85 years of age, Arthur Rubinstein gave a concert at the age of 89. Michelangelo and Titian were still creative at their 90s. Great scientists - Pavlov, Krylov, Zelinsky, Gamaleja, Michuryn - continued to experiment and lecture when they were in their eighties.

It is true that physical and even some mental abilities deteriorate with the age, and memory is visibly losing. Many people feel they could not keep up with the changes happening around them. There is a desire to dissociate themselves from the rest of the world. It is wrong. It is important not to be afraid of novelties, try at least to elementary understand it. Aft er all, intellectual capacity not only


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SOCIAL, ENVIRONMENTAL AND SOCIO-POLITICAL FACTORS OF ACTIVE LONGEVITY

President of the Russian Association of Gerontologists and Geriatrists,

D.Sc., Professor, Academician of the Russian Academy of Sciences, honoured worker of science of the Russian Federation

Professor Shabalin started his career in 1962 as a doctor of Omsukchansky regional hospital of the Magadan Region. From 1965 to 1975, he held various scientific posts of the Leningrad Scientific Research Institute of Hematology and Blood Transfusion. From 1975 to 1985 he was the director of the Institute. From 1985 to 1992 Prof. Shabalin was the Head of the Main scientific department of the RF Ministry of Public Health. From 1993 to 1997 he was the deputy minister of the RF Ministry of Public Health. From 1997 to 2013 he was the Director of the Russian Clinical Centre for Gerontology of the Russian Public Health Ministry. Since 2013 till present Professor Shabalin has been the Head of the Gerontology and Geriatry Department of the Russian National Research Medical University named after N.I. Pirogov.

Professor Shabalin is the author of 670 scientific works, 9 monographs, holds 72 patents for inventions, as an academic advisor he supervised 25 doctoral and 32 master’s theses.

by Prof. V.N. Shabalin, Prof. V.A. Grachev

President of the V. Vernadsky Nongovernmental Ecological Foundation, Russia;

D.Sc., Professor, Corr. Member of the Russian Academy of Sciences

Prof. Grachev started his career in 1960s as an engineer, then as a lecturer at the Penza State Polytechnical Institute. In 1990 he was elected a People’s Deputy, Deputy Chairman of the Committee on Science, Higher Education and Training at the Supreme Council of the Russian Federation. In 1993 - 1999 V. Grachev was the Head of Staff of the Federation Council Committee on Science, Culture, Education, Health and Ecology. In 1997 – 2007 he was elected a deputy of the State Duma, the Chairman of the Committee on Ecology. Prof. Grachev is an honorary member of the PACE. Since 2011 he has been the President of the Vernadsky Nongovernmental Ecological Foundation.

Prof. Grachev is the author of 243 inventions, 625 published works, 29 monographs, 10 textbooks, 15 manuals.

The most important demographic phenomenon at the turn of the 20th and 21st centuries was a global increase in life expectancy and, as a consequence, an adequate increase in the proportion of older people in the general population of the world. The growth rate of the elderly population is far ahead of the growth rate of the total population. At the same time, the older the age group, the more intense its population is growing. Dramatic aging of the population

is a major social problem that has a signifi cant impact on the economic, industrial and social relations of the present-day world. Importance of demographic aging is so great that the UN puts it on a par with the problem of preserving peace in the world.

Diversity of processes, aff ecting the aging of the human body, requires formation of a complex state and international measures

Vladimir A. Grachev Professor

Vladimir N. Shabalin Professor

to prevent the disease of aging, measures to ensure compliance with the dynamic adaptive capacity of the human body with natural and anthropogenic environmental changes.

Throughout the human history, there are many examples of longevity. It is known for the fact that there were people being up to 120-122 years

old. Women live longer than men. Jeanne Louise Calment lived 122 years. This Frenchwoman lived the longest life of all people. The oldest man is 118 years old. Apparently, these are the limits of human life.

Important facts are not only isolated cases of longevity, but also the general increase in life expectancy (Figure 1.).

Figure 1. Life expectancy of people

It is important to note as well that the important thing is not HOW MUCH, and HOW to live your life. There are many examples of active aging: the famous Russian actor V.M. Zeldin at his 99 continues to perform on stage. Well back in the early 30-ies of the last century he became famous for his roles in the movies (almost 85 years ago). Artist Boris Yefi mov lived 106 years, 103 years of which he regularly went to work. Shigechiyo Izumi of Japan lived longer than all men in the world - 120 years. His job seniority is 98 years.

No biological diff erences among centenarians have been found. They diff er in moderation in everything, calm character, sociability and love for their neighbours. Whereas their main feature is a permanent intellectual and physical LABOUR.

Most importantly is that one must make your brain work continually. Studies have shown that actively working with the brains makes it possible to off set the inevitable dying nerve cells well into a great

age, thus increasing the working quality of the remaining nerve cells. Here are the most obvious examples, showing that old age can be as fruitful as the youth. Sophocles wrote a brilliant tragedy “Oedipus” when he turned 100 years old. Leo Tolstoy, Voltaire, Goethe, George Bernard Shaw continued to create literary masterpieces at the age of eighty years and older. Ilya Repin, Ivan Aivazovsky created the best canvases at 80 - 85 years of age, Arthur Rubinstein gave a concert at the age of 89. Michelangelo and Titian were still creative at their 90s. Great scientists - Pavlov, Krylov, Zelinsky, Gamaleja, Michuryn - continued to experiment and lecture when they were in their eighties.

It is true that physical and even some mental abilities deteriorate with the age, and memory is visibly losing. Many people feel they could not keep up with the changes happening around them. There is a desire to dissociate themselves from the rest of the world. It is wrong. It is important not to be afraid of novelties, try at least to elementary understand it. Aft er all, intellectual capacity not only


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LEADERS

S o c r a t e s A l m a n a c ‘ H e a l t h a n d W e l l n e s s T o u r i s m ’S o c r a t e s A l m a n a c ‘ H e a l t h a n d W e l l n e s s T o u r i s m ’

Fig. 3. Wise active longevity

Fig.4. Friends and foes of longevity

strengthens the brain, but also develops confidence. For a man who exceeded sixty, there is only one recipe for longevity - work. This is the basis of longevity system (Fig. 3).

Sense of happiness is the psychological basis of longevity. And happiness is more dependent on our internal systems than the external conditions. Centenarians are able to control their mood and even see the silver lining of the cloud. For them, the vessel is always half full, rather than half empty.

A human being is a favorite child of evolution, because he is the most developed. Our improvement and elevation have processed everything both flora, and fauna. And the evolutionary quest for the best, most perfect structure now led to the creation of a higher sample of matter - it is the human brain, intelligence. And because

humanity has become the most progressive branch of biological matter, it was the evolution that increased the population of the homo sapiens species, and allowed him to live long.

Brain is our most lazy organ. The hardest thing is to overcome mental laziness. Brain often suffers not from work rather from idleness. It does not wear at all from an active work, but only consolidates and develops. Just like muscles, the brain grows old without work. It is true for all age groups. The active work of the brain is especially important in the old age for preserving memory and mental clarity. If it is possible, it would be necessary to continue working professionally, helping young colleagues write articles, books, learning foreign languages, solving crossword puzzles, memorizing poems and verses. It prevents decrepitude brain.

Fig.2 Ivan the Terrible here is 48 years old (1581), and the author of this article is 70.

However, we should not overstrain our brain because it could lead to stress, and there would be no benefits of such activity. An excessive stress is mentally and physically harmful. There are no professional athletes among centenarians, but there are many scientists (members of the Academy of Sciences live longer than businessmen).

Active longevity and psychological stress are incompatible. Among centenarians the share of laid back, friendly, "balanced" people actively involved in both mental and physical labor is the biggest (Fig. 4).

Personality development begins in childhood and never stops: it is necessary to purposefully think hard, act, perfecting the world and ourselves, accumulating knowledge and skills to pass them to the next generations. Education, professionalism and, to some extent, the success of each individual are the basis of the constant improvement. One should start to think about longevity already during his younger age. The correct way of life and self-development are the basis of longevity (Fig. 5).

Fig.5. Self-improvement is the basis of the wise active longevity


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Fig. 3. Wise active longevity

Fig.4. Friends and foes of longevity

strengthens the brain, but also develops confidence. For a man who exceeded sixty, there is only one recipe for longevity - work. This is the basis of longevity system (Fig. 3).

Sense of happiness is the psychological basis of longevity. And happiness is more dependent on our internal systems than the external conditions. Centenarians are able to control their mood and even see the silver lining of the cloud. For them, the vessel is always half full, rather than half empty.

A human being is a favorite child of evolution, because he is the most developed. Our improvement and elevation have processed everything both flora, and fauna. And the evolutionary quest for the best, most perfect structure now led to the creation of a higher sample of matter - it is the human brain, intelligence. And because

humanity has become the most progressive branch of biological matter, it was the evolution that increased the population of the homo sapiens species, and allowed him to live long.

Brain is our most lazy organ. The hardest thing is to overcome mental laziness. Brain often suffers not from work rather from idleness. It does not wear at all from an active work, but only consolidates and develops. Just like muscles, the brain grows old without work. It is true for all age groups. The active work of the brain is especially important in the old age for preserving memory and mental clarity. If it is possible, it would be necessary to continue working professionally, helping young colleagues write articles, books, learning foreign languages, solving crossword puzzles, memorizing poems and verses. It prevents decrepitude brain.

Fig.2 Ivan the Terrible here is 48 years old (1581), and the author of this article is 70.

However, we should not overstrain our brain because it could lead to stress, and there would be no benefits of such activity. An excessive stress is mentally and physically harmful. There are no professional athletes among centenarians, but there are many scientists (members of the Academy of Sciences live longer than businessmen).

Active longevity and psychological stress are incompatible. Among centenarians the share of laid back, friendly, "balanced" people actively involved in both mental and physical labor is the biggest (Fig. 4).

Personality development begins in childhood and never stops: it is necessary to purposefully think hard, act, perfecting the world and ourselves, accumulating knowledge and skills to pass them to the next generations. Education, professionalism and, to some extent, the success of each individual are the basis of the constant improvement. One should start to think about longevity already during his younger age. The correct way of life and self-development are the basis of longevity (Fig. 5).

Fig.5. Self-improvement is the basis of the wise active longevity


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LEADERS


Glaucoma is a chronic disease that causes vision loss through the degeneration of retinal ganglion cell (RGC) neurons and their axons in the optic nerve. It is a leading cause of irreversible blindness estimated to aff ect 79.6 million people worldwide by 2020 [1]. RGCs and the optic nerve, integral parts of the CNS, have demonstrated similar mechanisms of cell death in glaucoma to those of Alzheimer’s disease (AD), marking glaucoma as a neurodegenerative disease [2].

The intraocular pressure (IOP) is one of the main risk factor blamed for the pathology. The increased IOP in glaucoma may cause oxidative stress in retinal neurons. Although retinal circulation has an autoregulatory system to maintain a constant oxygen supply to the retina, it might be impaired under increased ocular pressure. A diminish in the retinal blood fl ow may lead to a kind of ischemic injury to retina, characterized by the formation of toxic reactive oxygen species (ROS) [3].

The ROS formation is a key process in many pathologic conditions. The relationship of glaucomatous optic excavation and retinal oxidation is still under investigation. Growing evidence supports that retinal ganglion cells in glaucomatous eyes are under oxidative stress that is associated with pathogenic mechanisms leading to glaucomatous neurodegeneration. Increased ocular pressure triggers molecular oxidation in the retina [4]. The reasons of increase in ROS in glaucoma were suggested to be due to diff erent mechanisms. The retina is especially susceptible to oxidative stress because of its high consumption of oxygen, its high proportion of polyunsaturated fatty acids, and its exposure to light.

The antioxidant enzymes act as free radical scavengers to cope with oxidation. Therefore, the antioxidative therapy might be of help in glaucomatous neuron degeneration.

Lowering IOP generally slows progression in glaucoma, but does not necessarily stop degeneration and there is a signifi cant

proportion of glaucoma patients who despite adequate IOP control continue to lose vision. In glaucoma, therefore, “neuroprotection” is restricted to mean therapy directed specifi cally at neurons in the whole visual pathway which is independent of its eff ects on IOP.

Intervention in the apoptotic cascades may provide therapeutic targets for drugs that could delay or ameliorate RGC loss in these chronic retinal neurodegenerative conditions. As the topical ocular hypotensive treatment is the main option in glaucoma nowadays, the direct neuroprotective eff ect of hypotensive eye drops is very important.

Evidence is mounting that topical ocular hypotensive exert direct neuroprotective eff ects in RGCs, both in vitro and in vivo.

The protective eff ect of beta-blocking medication on the visual fi elds of glaucoma patients has been studied, but with confl icting results [5]. In vivo experiments using topical and systemic application of β-blockers demonstrated the neuroprotective properties of betaxolol [6]. According to the Low Pressure Glaucoma Treatment Study2 (LoGTS), the α2 agonist brimonidine may have a benefi cial eff ect on visual function independent of IOP lowering [7]. Recent study demonstrated that topical brimonidine decreased MDA and increased GPx and catalase; hence it may act as an antioxidant [8].

Our recent research of antioxidant activity of carboanhydrase inhibitors for topical glaucoma treatment revealed that fi xed that they had the advantages over other eye drops, using for glaucoma, due to their high antioxidant activity [9].

Prostaglandin (PG) analogues have been a fi rst line drug for glaucoma treatment, because maximum intraocular pressure reduction is derived by once daily application without any systemic side eff ect in all kinds of glaucoma types. As well as the other ocular hypotensive drugs, PG analogues have been expected to have an additional eff ect to protect neurons independent of IOP reduction. Latanoprost showed neuroprotective eff ect on glutamate-induced

PRIMARY GLAUCOMA AS NEURODEGENERATIVE PATHOLOGY: NOVEL OPTIONS OF TREATMENT

Med.Sc.D., Professor, Head of the Diagnostic and Laser Treatment Department of the Ophthalmological Center of the Federal Medical and Biological Agency of the Russian Federation.

A member of the European Glaucoma Society and the American Academy of Ophthalmology, an author of 200 scientific papers, 3 textbooks and 7 inventions. Fields of scientific research are pseudoexfoliation syndrome/glaucoma, normal tension glaucoma, ocular blood flow and glaucoma laser/surgery.

by Natalia Kurysheva, Med.Sc.D., Professor

Natalia KuryshevaProfessor

Champions

Sea urchin – 200 years

Perch – 205 years

Cyprina islandica – 205 years

Arctic sea sponge – 205 years

Fig. 6. Life expectancy of fauna in the biosphere

Attitude towards older people is an important criterion of political, economic and moral well-being of society and the defi nition of a positive perspective for the further development.

Summing up, we would like to recommend organizations to use active longevity of older workers. Our recommendations to scientists-gerontologists is to develop a program of active longevity, together with trade unions and political parties, in those countries that support the PACE resolution on this issue.

In everyday life in Russia we see, unfortunately, a very diff erent picture. Despite the fact that the Russian Constitution stipulates in the Paragraph 2 of the Article 19 the prohibition of any form of restrictions imposed on the citizens’ rights on social affi liation, in-laws of the Russian Federation have bans and restrictions, prohibiting occupation of certain positions on the age indicator, excluding the actual physical and mental condition of the individual.

An unreasonable prohibition on practicing research and teaching positions (rector, provost, etc.) seems unreasonable. Since the Article 332 of the Labour Code (as amended. Federal law dd. 30.06.2006 N 90 -FZ) prohibits from holding the provost position at the age of 65 and older. Many examples of highly effi cient work of scientists, including in management positions, suggest that this namely age is a heyday for scientists, as well as of CEOs. The legendary Russian Minister of Atomic Energy Ye.P. Slavsky took his position when he was 60 years old and

then led one of the most important industries in the Soviet Union for almost 30 years. The whole world practice confi rms this thesis. Just look at the age composition of the parliaments of the leading countries of the world. In the Japanese parliament 60 years old means young parliamentarians. Wisdom is more important than all other factors. Wisdom comes with experience and knowledge, and those who accumulate knowledge during all the life, analyze the experience; the one who has proven that he is socially useful and needed by the society as a wise vault of the world experience, has the right to work.

And indeed, we should fall into a muse "Is it ethical to deny a person his right to work, a creative work!». In our view it is immoral and impractical in terms of the interests of the society.

In conclusion, let us say a few words about the prospects for longevity. Everybody is trying to fi nd some secrets –but there are no secrets. Bases are given above. The perspective lies only with the scientifi c research. The science of the 20th – 21st centuries works wonders. Biological processes in living nature are very long-lasting (Fig. 6).

What are we worse than perch, sea urchin or parrot? "They remember Pushkin and will remember us." We are confi dent that it is real to extend people’s life up to 100 years old, and the records like 120 years old and even 150 years are quite beatable. In the nearest future science is likely to discover inexhaustible sources of energy and reveal the reserves of prolongation of the human life.


- 45 -

LEADERS


Glaucoma is a chronic disease that causes vision loss through the degeneration of retinal ganglion cell (RGC) neurons and their axons in the optic nerve. It is a leading cause of irreversible blindness estimated to aff ect 79.6 million people worldwide by 2020 [1]. RGCs and the optic nerve, integral parts of the CNS, have demonstrated similar mechanisms of cell death in glaucoma to those of Alzheimer’s disease (AD), marking glaucoma as a neurodegenerative disease [2].

The intraocular pressure (IOP) is one of the main risk factor blamed for the pathology. The increased IOP in glaucoma may cause oxidative stress in retinal neurons. Although retinal circulation has an autoregulatory system to maintain a constant oxygen supply to the retina, it might be impaired under increased ocular pressure. A diminish in the retinal blood fl ow may lead to a kind of ischemic injury to retina, characterized by the formation of toxic reactive oxygen species (ROS) [3].

The ROS formation is a key process in many pathologic conditions. The relationship of glaucomatous optic excavation and retinal oxidation is still under investigation. Growing evidence supports that retinal ganglion cells in glaucomatous eyes are under oxidative stress that is associated with pathogenic mechanisms leading to glaucomatous neurodegeneration. Increased ocular pressure triggers molecular oxidation in the retina [4]. The reasons of increase in ROS in glaucoma were suggested to be due to diff erent mechanisms. The retina is especially susceptible to oxidative stress because of its high consumption of oxygen, its high proportion of polyunsaturated fatty acids, and its exposure to light.

The antioxidant enzymes act as free radical scavengers to cope with oxidation. Therefore, the antioxidative therapy might be of help in glaucomatous neuron degeneration.

Lowering IOP generally slows progression in glaucoma, but does not necessarily stop degeneration and there is a signifi cant

proportion of glaucoma patients who despite adequate IOP control continue to lose vision. In glaucoma, therefore, “neuroprotection” is restricted to mean therapy directed specifi cally at neurons in the whole visual pathway which is independent of its eff ects on IOP.

Intervention in the apoptotic cascades may provide therapeutic targets for drugs that could delay or ameliorate RGC loss in these chronic retinal neurodegenerative conditions. As the topical ocular hypotensive treatment is the main option in glaucoma nowadays, the direct neuroprotective eff ect of hypotensive eye drops is very important.

Evidence is mounting that topical ocular hypotensive exert direct neuroprotective eff ects in RGCs, both in vitro and in vivo.

The protective eff ect of beta-blocking medication on the visual fi elds of glaucoma patients has been studied, but with confl icting results [5]. In vivo experiments using topical and systemic application of β-blockers demonstrated the neuroprotective properties of betaxolol [6]. According to the Low Pressure Glaucoma Treatment Study2 (LoGTS), the α2 agonist brimonidine may have a benefi cial eff ect on visual function independent of IOP lowering [7]. Recent study demonstrated that topical brimonidine decreased MDA and increased GPx and catalase; hence it may act as an antioxidant [8].

Our recent research of antioxidant activity of carboanhydrase inhibitors for topical glaucoma treatment revealed that fi xed that they had the advantages over other eye drops, using for glaucoma, due to their high antioxidant activity [9].

Prostaglandin (PG) analogues have been a fi rst line drug for glaucoma treatment, because maximum intraocular pressure reduction is derived by once daily application without any systemic side eff ect in all kinds of glaucoma types. As well as the other ocular hypotensive drugs, PG analogues have been expected to have an additional eff ect to protect neurons independent of IOP reduction. Latanoprost showed neuroprotective eff ect on glutamate-induced

PRIMARY GLAUCOMA AS NEURODEGENERATIVE PATHOLOGY: NOVEL OPTIONS OF TREATMENT

Med.Sc.D., Professor, Head of the Diagnostic and Laser Treatment Department of the Ophthalmological Center of the Federal Medical and Biological Agency of the Russian Federation.

A member of the European Glaucoma Society and the American Academy of Ophthalmology, an author of 200 scientific papers, 3 textbooks and 7 inventions. Fields of scientific research are pseudoexfoliation syndrome/glaucoma, normal tension glaucoma, ocular blood flow and glaucoma laser/surgery.

by Natalia Kurysheva, Med.Sc.D., Professor

Natalia KuryshevaProfessor

Champions

Sea urchin – 200 years

Perch – 205 years

Cyprina islandica – 205 years

Arctic sea sponge – 205 years

Fig. 6. Life expectancy of fauna in the biosphere

Attitude towards older people is an important criterion of political, economic and moral well-being of society and the defi nition of a positive perspective for the further development.

Summing up, we would like to recommend organizations to use active longevity of older workers. Our recommendations to scientists-gerontologists is to develop a program of active longevity, together with trade unions and political parties, in those countries that support the PACE resolution on this issue.

In everyday life in Russia we see, unfortunately, a very diff erent picture. Despite the fact that the Russian Constitution stipulates in the Paragraph 2 of the Article 19 the prohibition of any form of restrictions imposed on the citizens’ rights on social affi liation, in-laws of the Russian Federation have bans and restrictions, prohibiting occupation of certain positions on the age indicator, excluding the actual physical and mental condition of the individual.

An unreasonable prohibition on practicing research and teaching positions (rector, provost, etc.) seems unreasonable. Since the Article 332 of the Labour Code (as amended. Federal law dd. 30.06.2006 N 90 -FZ) prohibits from holding the provost position at the age of 65 and older. Many examples of highly effi cient work of scientists, including in management positions, suggest that this namely age is a heyday for scientists, as well as of CEOs. The legendary Russian Minister of Atomic Energy Ye.P. Slavsky took his position when he was 60 years old and

then led one of the most important industries in the Soviet Union for almost 30 years. The whole world practice confi rms this thesis. Just look at the age composition of the parliaments of the leading countries of the world. In the Japanese parliament 60 years old means young parliamentarians. Wisdom is more important than all other factors. Wisdom comes with experience and knowledge, and those who accumulate knowledge during all the life, analyze the experience; the one who has proven that he is socially useful and needed by the society as a wise vault of the world experience, has the right to work.

And indeed, we should fall into a muse "Is it ethical to deny a person his right to work, a creative work!». In our view it is immoral and impractical in terms of the interests of the society.

In conclusion, let us say a few words about the prospects for longevity. Everybody is trying to fi nd some secrets –but there are no secrets. Bases are given above. The perspective lies only with the scientifi c research. The science of the 20th – 21st centuries works wonders. Biological processes in living nature are very long-lasting (Fig. 6).

What are we worse than perch, sea urchin or parrot? "They remember Pushkin and will remember us." We are confi dent that it is real to extend people’s life up to 100 years old, and the records like 120 years old and even 150 years are quite beatable. In the nearest future science is likely to discover inexhaustible sources of energy and reveal the reserves of prolongation of the human life.


- 46 -

LEADERS


retinal ganglion cell (RGC) death in vitro, and ischemia or axotomy-induced optic neuropathy mimicking glaucoma in animal models [10].

Nowadays fi xed combinations are becoming more and more popular in the treatment of glaucoma as well, they are not inferior by their hypotensive activity comparing to PG analogues. However, there are no data in the literature about the antioxidant properties either of PG analogues, or of fi xed combinations.

Purpose: to compare the antioxidant activity (AOA) of the most widely used prostaglandins analogs and fi xed combinations for topical glaucoma treatment.

Methods: the model of oxidation-induced haemolysis was used to study AOA of travoprost, bimatoprost and latanoprost and fi xed combinations (dorzolamide/timolol (Cosopt), dorzolamide/timolol (Dorzopt Plus), brinzolamid/timolol, latanoprost/timolol, brimonidin/timolol, travoprost/timolol and bimatoprost/timolol).

Antioxidant activity (AOA) was measured by a method based on the induced erythrocytes hemolysis. When adding solutions of tretbutyl (TB) and clotrimazole (CT) to a suspension of red blood cells washed from the plasma, their hemolysis is observed. Compounds with antioxidant activity (AO) inhibit hemolysis caused by free radicals (TB radicals). Clotrimazole (CT) has the ability to amplify the intensity of hemolysis. According to the degree of inhibition of free hemolysis it is possible to judge about the AO

activity of the test compound. The degree of hemolysis was determined by the change in hemoglobin concentration in the incubation medium. This method in detail has been described by us previously [9].

In this paper we investigated the antioxidant activity of three PG analogues: latanoprost (latanoprost 0.005%, Pfi zer), travoprost (Travoprost 0.004%, Alkon) and bimatoprost (Bimatoprost ophthalmic solution 0.03%, Allergan), and the main fi xed combinations such as dorzolamid/timolol (Cosopt: Dorzolamide hydrochloride 2% + Timolol maleate 0,5%, MSD Pharmaceuticals), dorzolamid/timolol (Dorzopt Plus: Dorzolamide hydrochloride 2% + Timolol maleate 0,5%, S.C. Rompharm Company S.R.L.), brinzolamid/timolol (Brinzolamid 1% + Timolol maleate 0,5%, Alcon), latanoprost/timolol (Latanoprost 0,005% + Timolol maleate 0,5%, Pfi zer), travoprost/timolol (Travoprost 0.004% + Timolol maleate 0,5%, Alkon), brimonidin/timolol (0,2% Brimonidin tartrato + Timolol maleate 0,5%, Allergan) and bimatoprost-timolol (Bimatoprost 0,03%+ Timolol maleate 0,5%, Allergan).

Results have revealed the highest AOA in travoprost (17%). However, it decreased upon adding larger quantities of the drug into the model system. In contrast to this, bimatoprost showed an increase of its AOA in higher concentration. Its AOA peaked at 38% in 120 mcl of bimatoprost. AOA in latanoprost was the lowest. Upon reaching 120 mcl, latanoprost exhibited oxidative properties. The data is represented in Fig.1.

Fig.1. Comparative characteristics of the antioxidant activity of prostaglandins analogues for topical hypotensive treatment of glaucomaNote: The abscissa shows the volume (mcl) of the PG analogues solution added to the model system (erythrocytes + solution of tretbutyl and clotrimazole). The vertical axis shows the percentage of inhibition of erythrocytes hemolysis when adding the drug into the model system containing the solution of tretbutyl and clotrimazole.

The blue colour shows the curve indicating the antioxidant activity of latanoprost, the red - bimatoprost, and the green - travoprost. It is noticeable that at the minimum of the investigated drug’s volume the highest AOA was observed in travoprost; at the maximum volume – in bimatoprost. In volume up to 100 mcl of latanoprost and up to 110 mcl of travoprost these drugs lead to the increased erythrocyte hemolysis.

Figure 2 shows the comparative characteristics of AOA fi xed combinations in the study of diff erent volumes of drugs added to the model system. The highest antioxidant activity was recorded in the combination of dorzolamide/timolol (Cosopt). It exceeded the AOA of other fi xed combinations when analyzing all the investigated volumes. It was increasing with the increase of the amount of the drug added to the model system (from 30 mcl to 60 mcl to 90 mcl), and accounted for 40 %, 52 % and 75%, respectively. It is noteworthy that the AOA of Cosopt twice exceeded the AOA of its analog - Dorzop Plus (Figure 2).

According to its antioxidant characteristics another drug is approaching to those fi xed combinations, also containing a carbonic anhydrase inhibitor (brinzolamide/timolol), the AOA of which was 16%, 42% and 54%, respectively, when the volume of the test drug was 30, 60 and 90 mcl. Among the fi xed combinations with prostaglandins, latanoprost/timolol took the lead regarding its antioxidant properties (Fig. 1).

DiscussionIn this study we compared the main medications for glaucoma treatment for their novel properties, concerning their antioxidant activity. The results showed that among PG analogues the highest antioxidant activity at the minimum doses of the studied drugs was characteristic for travoprost. This activity increased and reached the highest value at a dose of 60 mcl of travoprost, and further increasing the added amount of the drug decreased its AOA. A diff erent pattern was observed with respect to latanoprost. This PG analogue showed the lowest antioxidant activity and behaved as an oxidant, increasing hemolysis, when was tested with 120 mcl of the drug Among all the tested PG analogues only bimatoprost showed direct dose-dependent antioxidant activity: AOA of the drug increased with its volume under the study.

Takano N., et al. have recently demonstrated protective eff ects of bimatoprost on RGS in vitro, using the model of oxidative stress. Interestingly, this eff ect was dose-dependent: the greater the concentration of bimatoprost was added to the model system, which reproduced the reaction of free radical oxidation, the greater the surviving retinal ganglion cells were observed [11]. These results are consistent with those that we found in the model system in vitro, where oxidative stress led to hemolysis, and this hemolysis was inhibited by bimatoprost in dose-dependent manner. It has been postulated that PG analogues may have a potential to exert

Fig.2. Comparative characteristics of the antioxidant activity of fixed combinations for topical hypotensive glaucoma treatment Note: The abscissa shows the volume (mcl) of the antiglaucoma fi xed combination added to the model system (erythrocytes + solution of tretbutyl and clotrimazole). The vertical axis shows the percentage of inhibition of erythrocytes hemolysis when adding the drug into the model system containing the solution of tretbutyl and clotrimazole.


- 47 -

LEADERS


retinal ganglion cell (RGC) death in vitro, and ischemia or axotomy-induced optic neuropathy mimicking glaucoma in animal models [10].

Nowadays fi xed combinations are becoming more and more popular in the treatment of glaucoma as well, they are not inferior by their hypotensive activity comparing to PG analogues. However, there are no data in the literature about the antioxidant properties either of PG analogues, or of fi xed combinations.

Purpose: to compare the antioxidant activity (AOA) of the most widely used prostaglandins analogs and fi xed combinations for topical glaucoma treatment.

Methods: the model of oxidation-induced haemolysis was used to study AOA of travoprost, bimatoprost and latanoprost and fi xed combinations (dorzolamide/timolol (Cosopt), dorzolamide/timolol (Dorzopt Plus), brinzolamid/timolol, latanoprost/timolol, brimonidin/timolol, travoprost/timolol and bimatoprost/timolol).

Antioxidant activity (AOA) was measured by a method based on the induced erythrocytes hemolysis. When adding solutions of tretbutyl (TB) and clotrimazole (CT) to a suspension of red blood cells washed from the plasma, their hemolysis is observed. Compounds with antioxidant activity (AO) inhibit hemolysis caused by free radicals (TB radicals). Clotrimazole (CT) has the ability to amplify the intensity of hemolysis. According to the degree of inhibition of free hemolysis it is possible to judge about the AO

activity of the test compound. The degree of hemolysis was determined by the change in hemoglobin concentration in the incubation medium. This method in detail has been described by us previously [9].

In this paper we investigated the antioxidant activity of three PG analogues: latanoprost (latanoprost 0.005%, Pfi zer), travoprost (Travoprost 0.004%, Alkon) and bimatoprost (Bimatoprost ophthalmic solution 0.03%, Allergan), and the main fi xed combinations such as dorzolamid/timolol (Cosopt: Dorzolamide hydrochloride 2% + Timolol maleate 0,5%, MSD Pharmaceuticals), dorzolamid/timolol (Dorzopt Plus: Dorzolamide hydrochloride 2% + Timolol maleate 0,5%, S.C. Rompharm Company S.R.L.), brinzolamid/timolol (Brinzolamid 1% + Timolol maleate 0,5%, Alcon), latanoprost/timolol (Latanoprost 0,005% + Timolol maleate 0,5%, Pfi zer), travoprost/timolol (Travoprost 0.004% + Timolol maleate 0,5%, Alkon), brimonidin/timolol (0,2% Brimonidin tartrato + Timolol maleate 0,5%, Allergan) and bimatoprost-timolol (Bimatoprost 0,03%+ Timolol maleate 0,5%, Allergan).

Results have revealed the highest AOA in travoprost (17%). However, it decreased upon adding larger quantities of the drug into the model system. In contrast to this, bimatoprost showed an increase of its AOA in higher concentration. Its AOA peaked at 38% in 120 mcl of bimatoprost. AOA in latanoprost was the lowest. Upon reaching 120 mcl, latanoprost exhibited oxidative properties. The data is represented in Fig.1.

Fig.1. Comparative characteristics of the antioxidant activity of prostaglandins analogues for topical hypotensive treatment of glaucomaNote: The abscissa shows the volume (mcl) of the PG analogues solution added to the model system (erythrocytes + solution of tretbutyl and clotrimazole). The vertical axis shows the percentage of inhibition of erythrocytes hemolysis when adding the drug into the model system containing the solution of tretbutyl and clotrimazole.

The blue colour shows the curve indicating the antioxidant activity of latanoprost, the red - bimatoprost, and the green - travoprost. It is noticeable that at the minimum of the investigated drug’s volume the highest AOA was observed in travoprost; at the maximum volume – in bimatoprost. In volume up to 100 mcl of latanoprost and up to 110 mcl of travoprost these drugs lead to the increased erythrocyte hemolysis.

Figure 2 shows the comparative characteristics of AOA fi xed combinations in the study of diff erent volumes of drugs added to the model system. The highest antioxidant activity was recorded in the combination of dorzolamide/timolol (Cosopt). It exceeded the AOA of other fi xed combinations when analyzing all the investigated volumes. It was increasing with the increase of the amount of the drug added to the model system (from 30 mcl to 60 mcl to 90 mcl), and accounted for 40 %, 52 % and 75%, respectively. It is noteworthy that the AOA of Cosopt twice exceeded the AOA of its analog - Dorzop Plus (Figure 2).

According to its antioxidant characteristics another drug is approaching to those fi xed combinations, also containing a carbonic anhydrase inhibitor (brinzolamide/timolol), the AOA of which was 16%, 42% and 54%, respectively, when the volume of the test drug was 30, 60 and 90 mcl. Among the fi xed combinations with prostaglandins, latanoprost/timolol took the lead regarding its antioxidant properties (Fig. 1).

DiscussionIn this study we compared the main medications for glaucoma treatment for their novel properties, concerning their antioxidant activity. The results showed that among PG analogues the highest antioxidant activity at the minimum doses of the studied drugs was characteristic for travoprost. This activity increased and reached the highest value at a dose of 60 mcl of travoprost, and further increasing the added amount of the drug decreased its AOA. A diff erent pattern was observed with respect to latanoprost. This PG analogue showed the lowest antioxidant activity and behaved as an oxidant, increasing hemolysis, when was tested with 120 mcl of the drug Among all the tested PG analogues only bimatoprost showed direct dose-dependent antioxidant activity: AOA of the drug increased with its volume under the study.

Takano N., et al. have recently demonstrated protective eff ects of bimatoprost on RGS in vitro, using the model of oxidative stress. Interestingly, this eff ect was dose-dependent: the greater the concentration of bimatoprost was added to the model system, which reproduced the reaction of free radical oxidation, the greater the surviving retinal ganglion cells were observed [11]. These results are consistent with those that we found in the model system in vitro, where oxidative stress led to hemolysis, and this hemolysis was inhibited by bimatoprost in dose-dependent manner. It has been postulated that PG analogues may have a potential to exert

Fig.2. Comparative characteristics of the antioxidant activity of fixed combinations for topical hypotensive glaucoma treatment Note: The abscissa shows the volume (mcl) of the antiglaucoma fi xed combination added to the model system (erythrocytes + solution of tretbutyl and clotrimazole). The vertical axis shows the percentage of inhibition of erythrocytes hemolysis when adding the drug into the model system containing the solution of tretbutyl and clotrimazole.


- 48 -

LEADERS


neuroprotective effect by local administration. In some of the recent studies PG analogues indicated IOP independent neuroprotective effect on glutamate- and hypoxia-induced RGC death at clinically available intracameral concentration [12].

Recent studies by N.Osborne have shown an antioxidant effect of latanoprost: it was found that the drug promoted the development of the endogenous antioxidant glutathione [13].

The neuroprotective effect of PG analogues may be derived from the other mechanisms unrelated to the FP receptor stimulation. Many papers suggest that prostanoid EP2 is neuroprotective [14, 15]. Additionally, cyclooxygenase 2 (Cox2), one of the key enzymes to produce intrinsic PG by FP receptor stimulation, was reportedly neuroprotective [16].

In the course of the present study, for the first time PG analogues were compared in terms of their antioxidant activity, which refers to the neuroprotective properties of drugs.

Antioxidant protection plays a key role in oxidative stress conditions. Probably, with different neurodegenerative diseases, the activity of antioxidant defense molecules, that normally counteract the harmful effects of ROS, reduced. For example, the antioxidant enzymes superoxide dismutase (SOD), catalase, glutathione peroxidase (GSHPx) - and glutathione reductase (GSHRd) have reduced activity in the affected areas of the brain in Alzheimer’s disease and in the retina in glaucoma. For the first time we showed a decrease of the antioxidant protection of aqueous humor in glaucoma in 1996[17].

Application in the present study a model system with erythrocytes, hemolysis of which was caused by an oxidative stress, let us with a certain probability judge about the antioxidant activity of the tested PG analogs and fixed combinations. The results showed that antiglaucoma fixed combinations exhibited the highest antioxidant activity, containing carbonic anhydrase inhibitors (ICA). At the same time, the highest antioxidant activity was found in combination of dorzopt/timolol (drug Cosopt). This coincided with the data of the high antioxidant activity of dorzolamide obtained by us earlier [9].

Recent studies have shown that dorzolamide and timolol were able to protect mitochondrial DNA trabecular endothelial cells from oxidative stress [18], and with the combination of these drugs the antioxidant effect was amplified, which prevented trabecular from the damaging effect of hydrogen peroxide [19]. It should be emphasized that the explicit antioxidant properties of dorzolamide were particularly evident in relation to intact mitochondria trabecular endothelium, when the trabecular tissue was at least partially functioning. This substantiates the early administration of the dorzolamid, which may be the most effective in the initial stage of glaucoma. Clinical observations by V.Zanon-Moreno et al. about the high antioxidant activity of dorzolamide confirm this conclusion [20]. Attention should be paid to the recent findings about the ability of a fixed combination of dorzolamide with timolol to enhance the perfusion of the optic disk and retina [21].

Conclusion. Antioxidant activity of hypotensive drugs for glaucoma treatment is their important new features that are associated with the direct neuroprotective effect. The most commonly used

drugs at the present day are PG analogues and fixed combinations. They demonstrate a different antioxidant activity. Dorzolamide/timolol fixed combination has potential advantages over all other studied drugs, including fixed combinations and PG analogues, due to its highest antioxidant activity. This data should be taken into consideration as a novel option in glaucoma treatment.

References 1. Quigley H.A., Broman A.T. The number of people with glaucomaworldwide in 2010 and 2020. British Journal of Ophthalmology 2006; 90: 262–267.

2. Gupta N., Ang L.C., Noel de Tilly L., Bidaisee L., Yucel Y.H. Humanglaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex. British Journal of Ophthalmology 2006; 90:674–678.

3. Moreno MC, Campanelli J, Sande P, et al. Retinal oxidativestress induced by high intraocular pressure. Free Radic Biol Med. 2004;37:803–812.

4. Tezel G. Oxidative stress in glaucomatous neurodegeneration:mechanisms and consequences. Prog Retin Eye Res. 2006; 25:490–513.

5. Collignon-Brach J. Long-term effect of ophthalmic beta-adrenoceptor antagonists on intraocular pressure and retinal sensitivity in primary open-angle glaucoma. Curr Eye Res. 1992;11:1–3.

6. Osborne NN, Cazevieille C, Carvalho AL, Larsen AK, DeSantisL. In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent. Brain Res. 1997;751:113–123.

7. Krupin T, Liebmann JM, Greenfield DS, Ritch R, Gardiner S. Arandomized trial of brimonidine versus timolol in preserving visual function: Results from the Low-pressure Glaucoma Treatment Study. Am J Ophthalmol. 2011;151(4):671– 681.

8. Ozdemir G Ozdemir G., Tolun F., Gul M., Imrek S. RetinalOxidative Stress Induced by Intraocular Hypertension in Rats May be Ameliorated by Brimonidine Treatment and N-acetyl Cysteine Supplementation. J Glaucoma 2009; 18:662–665

9. Kurysheva N.I., Azizova O.A., Piryazev A.P. Comparative studyof antioxidant activity of carboanhydrase inhibitors for topical glaucoma treatment. Russian Ophthalmological Journal. 2011; 4(3):55 – 61.

10. Kanamori A., Naka M., Fukuda M., Nakamura M., Negi A.Latanoprost protects rat retinal ganglion cells from apoptosis in vitro and in vivo. Exp. Eye Res. 2009; 88:535–541.

11. Takano N., Kazuhiro Y. et al. Bimatoprost protects retinalneuronal damage via Akt pathway. Eur J Pharmacol. 2013; 702 (1-3): 56-61.

12. Yamagishi R., Aihara M., Araie M. Neuroprotective effects of

prostaglandin analogues on retinal ganglion cell death independent of intraocular pressure reduction. Experimental Eye Research. 2011;93:265-270.

13. Osborne, N.N., Ji, D., Abdul Majid, A.S., Fawcett, R.J., Sparatore,A., Del Soldato, P. ACS67, a hydrogen sulfide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture. Invest. Ophthalmol. Vis. Sci. 2010; 51(1): 284–294.

14. Hutchinson A.J., Chou C.L., Israel D.D., Xu W., Regan J.W.Activation of EP2 prostanoid receptors in human glial cell lines stimulates the secretion of BDNF. Neurochem. 2009; 54: 439–446.

15. Jiang J., Ganesh T., Du Y., Thepchatri P., Rojas A., Lewis I.,Kurtkaya S. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proc. Natl. Acad. Sci. U S A. 2010;107: 2307–2312.

16. Choi S.H., Aid S., Bosetti F. The distinct roles ofcyclooxygenase-1 and -2 in neuroinflammation: implications for translational research. Trends Pharmacol. Sci. 2009; 30:174–181.

17. Kurysheva NI, Vinetskaia MI, Erichev VP, et al. Contribution offree-radical reactions of chamber humor to the development of primary open-angle glaucoma. Vestnik Oftalmologii. 1996; 112:3–5.

18. Sacca S., La Maestra S., MicaleR., Larghero P. Ability ofDorzolamide Hydrochloride and Timolol Maleate to target mitochondria in glaucoma therapy // Arch Ophthalmol. 2011. V.129, N1. P.48-55.

19. Miyamoto N., Izumi H., Miyamoto R. et al. Nipradilol andtimolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress // Invest. Ophthalmol. Vis. Sci. 2009. V.50, N5. P.2777-2784.

20. Zanon-Moreno V., Garcia-Medina J.J., Gallego-Pinazo R.,Vinuesa-Silva I. Antioxidant status modifications by topical administration of dorzolamide in primary open-angle glaucoma //Eur. J. Ophthalmol. 2009. V.19, N 4. P.565-571.

21. Siesky B., Harris A., Kagemann L. Ocular blood flow and oxygendelivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy //Acta Ophthalmol. 2010. V.88, N 1. P.141–149.


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neuroprotective effect by local administration. In some of the recent studies PG analogues indicated IOP independent neuroprotective effect on glutamate- and hypoxia-induced RGC death at clinically available intracameral concentration [12].

Recent studies by N.Osborne have shown an antioxidant effect of latanoprost: it was found that the drug promoted the development of the endogenous antioxidant glutathione [13].

The neuroprotective effect of PG analogues may be derived from the other mechanisms unrelated to the FP receptor stimulation. Many papers suggest that prostanoid EP2 is neuroprotective [14, 15]. Additionally, cyclooxygenase 2 (Cox2), one of the key enzymes to produce intrinsic PG by FP receptor stimulation, was reportedly neuroprotective [16].

In the course of the present study, for the first time PG analogues were compared in terms of their antioxidant activity, which refers to the neuroprotective properties of drugs.

Antioxidant protection plays a key role in oxidative stress conditions. Probably, with different neurodegenerative diseases, the activity of antioxidant defense molecules, that normally counteract the harmful effects of ROS, reduced. For example, the antioxidant enzymes superoxide dismutase (SOD), catalase, glutathione peroxidase (GSHPx) - and glutathione reductase (GSHRd) have reduced activity in the affected areas of the brain in Alzheimer’s disease and in the retina in glaucoma. For the first time we showed a decrease of the antioxidant protection of aqueous humor in glaucoma in 1996[17].

Application in the present study a model system with erythrocytes, hemolysis of which was caused by an oxidative stress, let us with a certain probability judge about the antioxidant activity of the tested PG analogs and fixed combinations. The results showed that antiglaucoma fixed combinations exhibited the highest antioxidant activity, containing carbonic anhydrase inhibitors (ICA). At the same time, the highest antioxidant activity was found in combination of dorzopt/timolol (drug Cosopt). This coincided with the data of the high antioxidant activity of dorzolamide obtained by us earlier [9].

Recent studies have shown that dorzolamide and timolol were able to protect mitochondrial DNA trabecular endothelial cells from oxidative stress [18], and with the combination of these drugs the antioxidant effect was amplified, which prevented trabecular from the damaging effect of hydrogen peroxide [19]. It should be emphasized that the explicit antioxidant properties of dorzolamide were particularly evident in relation to intact mitochondria trabecular endothelium, when the trabecular tissue was at least partially functioning. This substantiates the early administration of the dorzolamid, which may be the most effective in the initial stage of glaucoma. Clinical observations by V.Zanon-Moreno et al. about the high antioxidant activity of dorzolamide confirm this conclusion [20]. Attention should be paid to the recent findings about the ability of a fixed combination of dorzolamide with timolol to enhance the perfusion of the optic disk and retina [21].

Conclusion. Antioxidant activity of hypotensive drugs for glaucoma treatment is their important new features that are associated with the direct neuroprotective effect. The most commonly used

drugs at the present day are PG analogues and fixed combinations. They demonstrate a different antioxidant activity. Dorzolamide/timolol fixed combination has potential advantages over all other studied drugs, including fixed combinations and PG analogues, due to its highest antioxidant activity. This data should be taken into consideration as a novel option in glaucoma treatment.

References 1. Quigley H.A., Broman A.T. The number of people with glaucomaworldwide in 2010 and 2020. British Journal of Ophthalmology 2006; 90: 262–267.

2. Gupta N., Ang L.C., Noel de Tilly L., Bidaisee L., Yucel Y.H. Humanglaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex. British Journal of Ophthalmology 2006; 90:674–678.

3. Moreno MC, Campanelli J, Sande P, et al. Retinal oxidativestress induced by high intraocular pressure. Free Radic Biol Med. 2004;37:803–812.

4. Tezel G. Oxidative stress in glaucomatous neurodegeneration:mechanisms and consequences. Prog Retin Eye Res. 2006; 25:490–513.

5. Collignon-Brach J. Long-term effect of ophthalmic beta-adrenoceptor antagonists on intraocular pressure and retinal sensitivity in primary open-angle glaucoma. Curr Eye Res. 1992;11:1–3.

6. Osborne NN, Cazevieille C, Carvalho AL, Larsen AK, DeSantisL. In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent. Brain Res. 1997;751:113–123.

7. Krupin T, Liebmann JM, Greenfield DS, Ritch R, Gardiner S. Arandomized trial of brimonidine versus timolol in preserving visual function: Results from the Low-pressure Glaucoma Treatment Study. Am J Ophthalmol. 2011;151(4):671– 681.

8. Ozdemir G Ozdemir G., Tolun F., Gul M., Imrek S. RetinalOxidative Stress Induced by Intraocular Hypertension in Rats May be Ameliorated by Brimonidine Treatment and N-acetyl Cysteine Supplementation. J Glaucoma 2009; 18:662–665

9. Kurysheva N.I., Azizova O.A., Piryazev A.P. Comparative studyof antioxidant activity of carboanhydrase inhibitors for topical glaucoma treatment. Russian Ophthalmological Journal. 2011; 4(3):55 – 61.

10. Kanamori A., Naka M., Fukuda M., Nakamura M., Negi A.Latanoprost protects rat retinal ganglion cells from apoptosis in vitro and in vivo. Exp. Eye Res. 2009; 88:535–541.

11. Takano N., Kazuhiro Y. et al. Bimatoprost protects retinalneuronal damage via Akt pathway. Eur J Pharmacol. 2013; 702 (1-3): 56-61.

12. Yamagishi R., Aihara M., Araie M. Neuroprotective effects of

prostaglandin analogues on retinal ganglion cell death independent of intraocular pressure reduction. Experimental Eye Research. 2011;93:265-270.

13. Osborne, N.N., Ji, D., Abdul Majid, A.S., Fawcett, R.J., Sparatore,A., Del Soldato, P. ACS67, a hydrogen sulfide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture. Invest. Ophthalmol. Vis. Sci. 2010; 51(1): 284–294.

14. Hutchinson A.J., Chou C.L., Israel D.D., Xu W., Regan J.W.Activation of EP2 prostanoid receptors in human glial cell lines stimulates the secretion of BDNF. Neurochem. 2009; 54: 439–446.

15. Jiang J., Ganesh T., Du Y., Thepchatri P., Rojas A., Lewis I.,Kurtkaya S. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proc. Natl. Acad. Sci. U S A. 2010;107: 2307–2312.

16. Choi S.H., Aid S., Bosetti F. The distinct roles ofcyclooxygenase-1 and -2 in neuroinflammation: implications for translational research. Trends Pharmacol. Sci. 2009; 30:174–181.

17. Kurysheva NI, Vinetskaia MI, Erichev VP, et al. Contribution offree-radical reactions of chamber humor to the development of primary open-angle glaucoma. Vestnik Oftalmologii. 1996; 112:3–5.

18. Sacca S., La Maestra S., MicaleR., Larghero P. Ability ofDorzolamide Hydrochloride and Timolol Maleate to target mitochondria in glaucoma therapy // Arch Ophthalmol. 2011. V.129, N1. P.48-55.

19. Miyamoto N., Izumi H., Miyamoto R. et al. Nipradilol andtimolol induce Foxo3a and peroxiredoxin 2 expression and protect trabecular meshwork cells from oxidative stress // Invest. Ophthalmol. Vis. Sci. 2009. V.50, N5. P.2777-2784.

20. Zanon-Moreno V., Garcia-Medina J.J., Gallego-Pinazo R.,Vinuesa-Silva I. Antioxidant status modifications by topical administration of dorzolamide in primary open-angle glaucoma //Eur. J. Ophthalmol. 2009. V.19, N 4. P.565-571.

21. Siesky B., Harris A., Kagemann L. Ocular blood flow and oxygendelivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy //Acta Ophthalmol. 2010. V.88, N 1. P.141–149.


Dear Sirs,We invite you to take part in the next Summit of Leaders, which will be dedicated to science and education issues and take place in the heart of world education - the Oxford city, UK between 12-15th October, 2014.Oxford Summit of Leaders – an annual forum of businessmen and investors, academics and scientists, university presidents and lectors, and Europe Business Assembly (EBA) members from around the world.Plenty of functions that will give summit participants the opportunity to meet new business partners and clients, promote their institutions widely, exchange ideas, and discuss many important topics with colleagues.

TWO DAYS SCIENCE AND EDUCATION CONFERENCEThis time, among actual education trends three main cases have been accentuated: • University of the Future; • Effective Forms of Education, Science and Production Integration; • Improving the Educational Process.

EBA - CONTEST: Science and Education. University of the Future • Participants from more than 30 countries; • Experienced jury and experts; • Online voting.

EXPRESS EXHIBITION• Connect with as many as 30 educational services providers.• Introduce your institution/enterprise, product or services to Oxford Summit of

Leaders participants and exhibition attendees.• Enhance your brand and position in the market.• Gain insight on current educational sector trends and best practices

EUROPE BUSINESS ASSEMBLY BUSINESS MEETING WITH THAMES VALLEY CHAMBER OF COMMERCE

Thames Valley Chamber of Commerce and UK business circles will meet prominent regional companies – winners of Europe Business Assembly awards.

RECTORS’ GATHERING AND OXFORD ACADEMIC SOCIETY ESTABLISHINGThis year in the framework of the Rectors’ gathering the Oxford Academic Society memorandum on establishing will be signed and new members will be admitted.

OXFORD LECTORS’ BUREAU The Oxford Lectors’ Bureau represents and works with some of the most influential people in the fields of higher education and science, from politicians and economists to thought leaders and entrepreneurs.

SOCRATES ALMANAC 2014The main points of interest are in science, education and business. ISSN 2053-4736. Published in Oxford. Printed and online version. A unique opportunity to present yourself! The first edition of the Socrates Almanac, published to coincide with last Decembers Oxford Summit of Leaders has just been accepted onto the shelves of the historic Oxford Bodleian Library

SOCRATES AWARDS CEREMONY ‘ACHIEVEMENTS 2014’Grand Ceremony: presentation of SOCRATES Awards for 2014 in the fields of state management, business, economy, science, education and culture. We look forward to welcoming you in Oxford.

Your sincerely, Programme Committee of Oxford Summit of Leaders

Science and Education. Innovative Models of Development 12–15 October 2014, Oxford, United Kingdom

For more details please visit http://www.summitofleaders.co.uk/en/summit/oxford-ukTo take part in the Oxford Summit of Leaders, please contact:

Phone/fax: + 44 (0) 1865 251 133, email: [email protected], [email protected]

Ukraine. The Best Investment Project 2014

KYIV SUMMIT OF LEADERS ‘Ukraine. Hotel Industry, Cities Life Support and Town Planning,

Tourism and Agro-industrial Complex’

November 25, 2014, Kyiv, Ukraine

LEADERS

www.summitofleaders.co.uk

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LEADERS

The international ‘Stars of Health, Wellness and Tourism’ contest highlights new trends in medicine, recreation, tourism and industry infrastructure to the world business community, and uncovers regional leaders in the fields of resort and hotel management, healthcare, travel and health goods.

Main tasks:• providing patients with reliable, current and comprehensive information• encouraging medical, dental, plastic surgery and wellness providers to supply the highest possible level of services• promotion of travel destinations, resorts, leading hospitals and clinics• assessment of innovative legal and financial instruments for the healthcare and travel industries

Representatives from different sub-sectors of the healthcare and wellness sector will be studied in order to create a database of the best healthcare and travel companies, world leading resorts and holiday cities. Winners will get the opportunity to mark their goods/services with the contest logo and will be certified as a ‘Star of Health, Wellness and Tourism’. The logo and mark can be used for PR and image purposes during the first year.

INOVATION IN MEDICAL TOURISMBlu Skin and Cosmetology Clinic & Medi Spa, IndiaPerfect Beauty Aesthetics and Anti-Aging Centres, IndonesiaTerme della Versilia, ItalyTi Sana Detox Retreat & Spa, ItalyThe International Medical Center – MMC ODA, RussiaChakrapani Ayurveda Clinic & Research Center, India

LEADERSHIP IN HOSPITALITYDe Palma Group of Hotels, MalaysiaHotel by the Red Canal, Mandalay, MyanmarAl Maha Desert Resort & Spa, UAEMeikles Hotel, ZimbabweSymphony Style Hotel, Kuwait

MEDICAL PERSON OF THE YEARProf. Dr. Doru Pamfil, Rector, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, RomaniaKravchik Maximilian, Doctor-Neurosurgeon, Head of the Department of Rehabilitation ‘PAIN CLINIC’, ‘ММC ОDА’, RussiaProfessor Dusica Lecic-Tosevski, MD, PhD, Neuropsychiatrist, Psychotherapist and Professor of Psychiatry at the School of Medicine, University of Belgrade, SerbiaZinchenko Viktor, Deputy CEO of Isida Hospital, IVF specialist, embryologist, Honored Doctor of UkraineDr. Luis Filipe, Traditional Chinese Medicine Master, AngolaProf. Dr. Bojan Zalar, Director General, University Psychiatric Hospital, SloveniaRobert Gajda M.D., PhD, Director, Medical Center Gajda-Med, PolandNatalia Zemnaya (Zubitskaya), President, Public organization ‘All-Ukrainian organization – Ukrainian society ‘Green Planet’, UkraineDr. Nahi Yousif Yaseen, Professor of cancer and medical genetics, Iraqi centre for cancer and medical genetics research, Al-Mustansiriya University, Baghdad, IraqDina Turakbayeva, Chief Medical Officer, 1st Perinatal Center of Astana, Republic of Kazakhstan Abdul Mutalib Abdul Ghany Nasser, Dean, Baghdad Pharmacy College, IraqProf. Dr. Oral B. Ospanov, President of Association of Endoscopic Surgery of Kazakhstan (AESK), Republic of KazakhstanAzimova Zhanna, Founder of clinic DARUS and DARUS+, Republic of Kazakhstan

EXCELLENCE IN MEDICAL MANAGEMENT AND INFRASTRUCTUREGestar Pharma S.A.S, ColombiaThe International Medical Center – MMC ODA, RussiaGreen Planet, Enterprise, UkraineWockhardt Ltd, India

BEST HOLIDAY DESTINATION/RESORT

STARS

OF

HEA

LTH, WELLNESS AND

TOU

RISM

FINALISTS of 2014:

INTERNATIONAL CONTEST ‘STARS OF HEALTH, WELLNESS AND TOURISM’

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LEADERS

Adana Municipality, Turkey - Mayor Mr. Hüseyin SözlüLaoag City, Philippines - Mayor Hon. Michael V. FariñasMejillones Municipality, Chile - Mayor Mr. Marcelino Carvajal FerreiraMunicipal Council of Penang Island, Malaysia - President Patahiyah IsmailMunicipal Council of Seberang Perai, Malaysia - President Ms. Maimunah Mohd SharifSanliurfa Municipality, Turkey - Mayor Mr.Celalettin GüvençViana do Castelo Municipality, Portugal - Mayor Mr. José Maria CostaViseu Municipality, Portugal - Mayor Mr. Almeida HenriquesSungai Petani Municipal Council, Malaysia - President The Honourable Datuk Haji Ismail bin Haji SaidSemarang Municipality, Indonesia - Mayor Mr. Hendrar Prihadi Local Government Unit Cauayan City Isabela, Philippines - Mayor Hon. Bernard Faustino M. DyMunicipality of Bitola, Macedonia - Mayor Vladimir Taleski

TOP MEDICAL/TRAVEL/HOSPITALITY WEB-SITE

Temos International GmbH, GermanyMedical Center Gajda-Med, PolandSoundarapandian Bone and Joint Hospital and Research Institute Private Limited, IndiaSaudi German Hospital Dubai, UAENoble Smile Dental Care Clinic, Saudi ArabiaMunicipal Council of Seberang Perai, MalaysiaELKA S.A., AlbaniaLocal Government Unit Cauayan City Isabela, PhilippinesMunicipal Council of Sungai Petani, Kedah, MalaysiaNew Life Global Network, GeorgiaEO DENT DENTAL CLINIC, BulgariaSpecial Surgery Hospital Filip Vtori, Macedonia

INNOVATIVE HEALTHCARE PRODUCTSNutrition, health food and goods producers and suppliersCentral Pharmaceuticals Ltd., BangladeshGestar Pharma S.A.S, ColombiaTRAPHACO Joint Stock Company, Vietnam

LEADING HEALTHCARE PROVIDERAbu Dhabi Falcon Hospital, United Arab EmiratesInstitute of Mental Health, SerbiaIsida Hospital, UkraineMedical Center NADEJDA, BulgariaNoble Smile Dental Care Clinic, Saudi ArabiaThe International Medical Center – MMC ODA, RussiaSaudi German Hospital Dubai, United Arab EmiratesShifa International Hospitals Limited, PakistanSoundarapandian Bone and Joint Hospital and Research Institute Private Limited, IndiaUniversity Psychiatric Hospital, SloveniaMedical Center Gajda-Med, PolandEO Dent Dental Clinic, BulgariaNew Life Global Network, GeorgiaSpecial Hospital for Surgical Disease Fillip II, MacedoniaBali Royal Hospital, IndonesiaSwiss Health, Switzerland

HEALTHCARE INNOVATION/PROGRAMME OF THE YEARThe International Medical Center – MMC ODA, RussiaHospital ‘MediStyle’, AzerbaijanNikolai Nasikovskyy, President of Ukrainian Association of Manual Therapyis, UkraineLLP Medical Center Darus and LLP Medical Center Darus Plus, Republic of Kazakhstan

Winners will be announced at the Health and Wellness Tourism Summit of Leaders summing up, 3 July.

INTERNATIONAL CONTEST ‘STARS OF HEALTH, WELLNESS AND TOURISM’

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LEADERS

#II/VI/XIV, 23 June 2014, Oxford, UK

THE INTERNATIONAL AWARD ‘UNITED EUROPE’ for personal contribution to the development of European integration:

Rostyslav Zheliaskov – Director ‘Green Planet’ Enterprise, UkraineTHE INTERNATIONAL AWARD ‘THE NAME IN SCIENCE’

By decision of the Socrates Committee in accordance with Provision, paragraphs 1, 2, names of the following persons have been recorded in the World register of outstanding scientists

of the 21st century with awarding a medal of fame ‘For contribution to world science’ (№ SC-I/NS 23 June 2014)Nahi Yousif Yaseen – Director General, Iraqi Centre For Cancer And Medical Genetics Research, Iraq Maximilian Kravchik - Head of the Department neurosurgery of the International Medical Center of treating the most serious pathology ‘The International Medical Center - MMC ODA’, RussiaDina Turakbayeva - Chief medical officer 1st Perinatal Center, Republic of Kazakhstan, AstanaVasile Burlui - President Of The University Apollonia University of Iasi, Romania

THE INTERNATIONAL AWARD ‘NAME OF THE YEAR’ for professional achievements

Aksiniia Zheliaskova - Consultant ‘Green Planet’ Enterprise, UkraineZorina Zheliaskova – Consultant ‘Green Planet’ Enterprise, Ukraine

INTERNATIONAL PRIZE ‘BEST CLINIC’ for leading positions in medical sphere:

Noble Smile Dental Care, Saudi Arabia - Medical Director Ahmed ShamiyahEO Dent Dental Clinic, Bulgaria – Manager Valentin PavlovMedical Center Gajda-Med., Poland – Director Gajda Robert

INTERNATIONAL PRIZE ‘BEST HOSPITAL’ for leading positions in medical sphere:

Bali Royal Hospital, Indonesia - Director of Marketing and Business Development Ida Ayu Oka Purnama WatiSaudi German Hospital Dubai, UAE – CEO Reem OsmanSoundarapandian Bone and Joint Hospital and Resarch Institute Private Limited, India – Director Sivamurugan SoundarapandianSpecial Surgery Hospital Filip Vtori, Macedonia - General Manager Dr. Zan Mitrev

INTERNATIONAL PRIZE ‘BEST DOCTOR’ for leading positions in the sphere of traditional medicine, subcategory Chinese medicine:

Luis Filipe - Doctor of Traditional Chineese Medicine, AngolaINTERNATIONAL PRIZE ‘BEST CITIES’

for dynamic growth of the city with presenting the head of the municipality the title ‘Manager of the year’:Local Government Unit Cauayan City Isabela, Philippines - City Mayor Bernard Faustino Dy Municipal Council of Sungai Petani, Kedah, Malaysia – President Ismail SaidMunicipal Council of Seberang Perai, Malaysia – President Maimunah Mohd SharifSemarang Municipality, Indonesia - Mayor Hendrar Prihadi

THE INTERNATIONAL PRIZE ‘BEST ENTERPRISES’ for professional achievements in commercial activities

‘Kyzylkum Tyulpan’, Republic of Uzbekistan – Director Natalya AkhmadulinaCentral Pharmaceuticals Ltd., Bangladesh - Managing Director Munsur AhamedChemstar Paints Ind. (Nig.) Ltd., Nigeria - Chief Executive Officer Emmanuel Aderemi AwodeCivil Engineering Construction Corporation No.4, Vietnam - General Director Ngoc Hoa LeELKA SA, Albania - General Manager Eli Jorgji Ghana National Gas Company, Ghana – CEO George Sipa-Adjah YankeyHurlag Technologies Limited, Nigeria - Managing Director Olasoji R. OlagunjuInsol d.o.o., Slovenia - Owner and CEO Marko LikonMaxidor, Republic of South Africa – CEO Miklos Hegyi Medical-wellness center ‘Sailaukhan’, Republic of Kazakhstan – Director Sailaukhan AuyelbayevaNanopac (M) Sdn Bhd, Malaysia - Chief Executive Officer Kok Leong ChengNew Life Global Network, Georgia – Founder Mariam Kukunashvili Swiss Biostadt Limited, Nigeria - Chief Executive Officer Emmanuel AjayiGazosiliсat, Private Enterprise, Republic of Belarus - Director General Rachitskiy IgorLeader Tread De Mocambique, Mozambique - General Manager Ana Paula Henriques

THE INTERNATIONAL PRIZE ‘EUROPEAN QUALITY’for continuous efforts to achieve high quality in accordance with the European Standard

Baghdad College of Pharmacy, Iraq -Dean Prof. Dr. Abdulmuttaleb Abdul Ghani Naser Al–JawharPrivate Medical Practice Sarclinic, Russia - General director Vladimir Pechennikov‘Vodnye Resursy – Marketing’ LLP, Republic of Kazakhstan - Director General Anarbek Orman

INTERNATIONAL AWARD ‘GOLDEN JAGUAR’ for exemplary business achievements demonstrating high professionalism and interdependence within partnership relationships:

Mohammad Nasr Abdeen - Chief Executive Officer Union National Bank, UAEINTERNATIONAL QUALITY CERTIFICATES OF THE SWISS INSTITUTE OF QUALITY STANDARDS (SIQS)

are given to companies for international quality of products/services standardsD/I/SIQS, 23 June 2014, Switzerland

Wellness Center of Massimov LLP, Republic of Kazakhstan - Director General Kazhimkan Massimov Private clinic SHAPAGAT, Republic of Kazakhstan- Chief Doctor Amanzhol Adayev National Scientific Medical Research Center JSC, Republic of Kazakhstan - Director General Baigenzhin Abai Ordabasy Kus Ltd, Republic of Kazakhstan - Director General Murat TagayevLLP Medical Center Darus and LLP Medical Center Darus Plus, Kazakhstan - Founder of clinics Darus and Darus Plus Zhanna Azimova‘Meat Processing Plant Bizhan’ LLP, Republic of Kazakhstan - Director General Khadisha Bizhan

DECISION ON REWARDINGof outstanding political figures, businessmen and scientists with prestigious EBA rewards

www.summitofleaders.co.uk

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