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CURRICULUM VITAE (abbreviated)

PAUL ERNEST PEPE

OFFICE ADDRESS: Office of the Executive Vice President for Health System Affairs, University of Texas Southwestern Medical Center at Dallas, B-11 5323 Harry Hines Boulevard, Dallas, Texas 75390-9131 HOME ADDRESS: 11318 Dujon Lane Dallas, Texas 75218-1390 TELEPHONE: Work: 214-648-4812 (UT Southwestern Administration Offices) Fax: 214-648-8423 (UT Southwestern Administration Offices)

E-MAIL: Paul.Pepe@UTSW.edu UNIVERSITY WEBSITE

BIOGRAPHY: http://profiles.utsouthwestern.edu/profile/43741/paul-pepe.html MARITAL STATUS: Married: Linda Pepe Former TV News Producer, CBS Affiliate, Houston, and ABC Affiliates, Houston and New York, and Fox Affiliate, Dallas Married, 1990, Northern Sporades Islands, Greece CHILDREN: Daughter: Lauren June Pepe (Born: 1992) Cum Laude Graduate, University of Richmond, 2016 Class President (2012- 2014) Chair, Student Senate (2014-2016) Primary Area of Study: Leadershp Admitted Jepson School of Leadership (2015) Received Numerous Awards including University Leadership Award at Graduation Teaching Fellow, the Brunswick School, Greenwich, CT and Teaching Master’s Degree Candidate, Manhattanville College (2016-2018) Son: Michael Vincent Pepe (Born: 1994) Graduated American University, May 2017 Washington Mentorship Program, 2013 Primary Area of Study: Business President, Leonard Hall (2013-2014) American University Residence Hall Association

Graduated May 14, 2017 with Bachelor of Science in Business Administration (BSBA) Degree with specialization in Public Asset Management

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GENERAL EDUCATION: Location: Degree/Date:

Undergraduate Boston University* B.A., major in Biology Education Boston, Massachusetts (Magna Cum Laude)

(1968-1972) Phi Beta Kappa (May 1972) * won distinguished alumnus award in 1987 --- and again in 2007

Medical School University of California* M.D., Medicine

San Francisco, California Alpha Omega Alpha (1972-1976) (April 1976)

* Chosen Class Speaker, 25th Anniversary Reunion in 2001 and runner-up nominee for distinguished alumnus award in 2007

Public Health University of Texas* M.P.H. School Houston, Texas in Health Services Organization

(1994-1995) and Economics (August 1995)

MASTER'S DEGREE THESIS: Pepe PE. Improving the criteria for waiving resuscitation efforts for out-of-hospital cardiac arrest. For Master's Degree in Public Health (MPH) in Community Health (Health Services Organization); Degree awarded August 10, 1995 by University of Texas Health Sciences Center at Houston, School of Public Health.

Subsequently appointed (and remained) a Professor in Public Health at the School, both Houston and Dallas Campuses

SPECIAL PROFESSIONAL COURSES: Location: Degree/Date:

Public Health Harvard University Program for Chiefs School Boston, MA of Clinical Services

(1999) (January 1999)

* was funded, in part, through scholarship award from the Association of Academic Chairs of Emergency Medicine

Government Security Dallas Fire Rescue Weapons of Mass Destruction Education Dallas, TX Specialist

(2000-2001) (March, 2001)

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POSTGRADUATE MEDICAL TRAINING: SUPERVISOR

Internship Internal Medicine Robert G. Petersdorf, M.D.

University of Washington Chairman Seattle, WA (1976-1977)

Residency Internal Medicine Robert G. Petersdorf, M.D. University of Washington Chairman Seattle, WA (1977-1979)

Fellowships Respiratory Diseases Leonard D. Hudson, M.D. and Critical Care Division Head (Clinical/Research) Department of Medicine University of Washington Seattle, WA (1979 -1982) Trauma* C. James Carrico, M.D. (Clinical/Research) Chairman Department of Surgery University of Washington Seattle, WA (1981-1982)

*co-funded and concurrent with third year of Critical Care Medicine Fellowship (both leading to certificates)

HISTORY OF EMPLOYMENT: SUPERVISOR 1976 –1979 Intern and Resident Robert G. Petersdorf, M.D. Department of Medicine Chairman University of Washington Seattle, Washington 1979 -1982 Senior Fellow in Pulmonary Leonard D. Hudson, M.D. and Critical Care Medicine Program Director Department of Internal Medicine University of Washington Seattle, Washington 1981 –1982 Senior Fellow in Trauma C. James Carrico, M.D. Department of Surgery Chairman University of Washington Seattle, Washington 1981 -1982 Instructor Leonard D. Hudson, M.D. Department of Chief of Critical Care Internal Medicine and Surgery University of Washington

and

Attending Staff Emergency Trauma Center and Critical Care Units, University of Washington Harborview Medical Center, Seattle, Washington

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1982 -1988 Assistant Professor Antonio M. Gotto, M.D. Tenure Track, Full-time Chair, Department of Medicine Department of Medicine Baylor College of Medicine) and

Attending Staff Ben Taub Emergency-Trauma Center Harris County Hospital District and

Director of Emergency Kathryn J. Whitmire Medical Services Mayor City of Houston, Texas

1988 -1994 Associate Professor William T. Butler, M.D. (Full-time Faculty, Tenured) President, Depts of Medicine, Surgery Baylor College of Medicine Pediatrics and Family Medicine and

Attending Staff Antonio M. Gotto, M.D. Ben Taub Emergency-Trauma Ctr, Chairman, Internal Medicine

Harris County Hospital District and

Director, Emergency Robert C. Lanier Medical Services System Mayor Houston, Texas

1994 -1996 Professor Ralph D. Feigin, M.D. (Full-time Faculty, Tenured) President, Baylor College Departments of Medicine of Medicine and Pediatrics, Baylor College of Medicine and

Attending Staff Antonio M. Gotto, MD Ben Taub Emergency-Trauma Chairman/Dept Medicine Center, Harris County Hospital District and

Director, City of Houston Emergency Robert C. Lanier Emergency Medical Services System Mayor

1996 -1998 Professor and Chairman, Barbara F. Atkinson, M.D. (Full-time Faculty, Tenured) Dean, MCPHUSM Department of Emergency Medicine Medical College of Pennsylvania/ Hahnemann University School of Medicine (MCPHUSM), Pittsburgh Campus and

Director, Emergency Services Connie Cibrone Allegheny General President & CEO 1998 - 2000 Chairman, Connie Cibrone Department of Emergency Medicine President & CEO Allegheny General Hospital (AGH) (medical school dissolved due to bankruptcy)

and

Emergency Medical Director Margaret E. Trimble Commonwealth of Pennsylvania Director, Office of EMS Pennsylvania Department of Health

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___________________________________________________________________________ 2000 - 2014 Professor of Surgery, Medicine Robert V. Rege, MD (thru 2013) Pediatrics, Public Health and Michael A. Choti, MD (2013-14) Riggs Family Chair Chair, of Surgery in Emergency Medicine Deborah Diercks, MD (fall 2014- present)

UT Southwestern Medical Center Chair, Emergency Medicine (Full-time, tenured, endowed chair) and

Chair, Emergency Services (thru Sept 2014) Ron Anderson, M.D. Parkland Health & Hospital System President and CEO Dallas, Texas (Feb 2000 thru Jan 2011)

Frederick P. Cerise, MD, MPH President and CEO

(Current)

Deborah Branson,

Chair, Board of Managers (through 2014) and

Medical Director, Bruce A. Myer, MD, MBA fDallas Area Biotel (EMS) System Execuive Vice President, Dallas, TX and Surrounding Municipalities Health System Affairs UT Southwestern

and

Director, City of Dallas Medical A.C. Gonzalez Emergency Services for Dallas City Manager Public Safety, Public Health, and Homeland Security, Dallas TX and Professor, Raul Caetano MD, MPH, PhD Emergency Medical Education Dean School of Health Professions, University of Texas Southwestern Medical Center Dallas, TX and Adjunct Professor, Roberta B. Ness, MD, MPH Mgmt, Policy & Community Health Dean School of Public Health University of Texas Health Sciences Center Houston, TX and 2009 - 2014 Chair, Emergency Medicine Residency Susan Cox, M.D. University Medical Center at Brackenridge Regional Dean University of Texas Southwestern Medical Center Austin Campus, Austin, TX (38 Core Faculty & 8 residents per yr in a 3 yr program)

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________________________________________________________________________________

CURRENT POSITION 2015 - present Professor of Surgery, Medicine Bruce A. Meyer, MD, MBA Pediatrics, Public Health, Executive Vice President Emergency Medicine, Allied Health; Health System Affairs and Riggs Family Chair UT Southwestern in Emergency Medicine University of Texas Southwestern Medical Center (Full-time, tenured, endowed chair)

and

Director, Regional Out-of-Hospital Mobile Care Systems and Disaster/Event Preparedness Office of Health System Affairs, University of Texas Southwestern Medical Center

and

Director, City of Dallas Medical T.C. Broadnax Emergency Services for Dallas City Manager Public Safety, Public Health, and Homeland Security, Dallas TX and Professor, Jon W. Willamson, PhD Emergency Medical Education Dean School of Health Professions, University of Texas Southwestern Medical Center Dallas, TX and

Adjunct Professor, Eric Boerwinkle, Ph.D. Management, Policy & Community Health Dean School of Public Health University of Texas Health Sciences Center Houston, TX _________________________________________________________________________________ BOARD CERTIFICATIONS

o Certified as a Diplomate, NATIONAL BOARD of MEDICAL EXAMINERS, (July 1, 1977)

o Certified by the American Board of Internal Medicine (ABIM) as a Diplomate in the Specialty of INTERNAL MEDICINE, (September 12, 1979 -- no expiry)

o Certified by the American Board of Internal Medicine (ABIM) as a Diplomate in the Subspecialty of PULMONARY DISEASES, (November 9, 1982 -- no expiry)

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o Certified by American Board of Emergency Medicine (ABEM) as a Diplomate in the Specialty of EMERGENCY MEDICINE (September 30, 1987 --- December 31, 2025)

▪ Re-certified by the American Board of Emergency Medicine (ABEM) as a Diplomate in

Specialty of EMERGENCY MEDICINE (December 27, 1996 ---- December 31, 2006)

▪ Re-certified by the American Board of Emergency Medicine (ABEM) as a Diplomate in Specialty of EMERGENCY MEDICINE (December 23, 2005 ---- December 31, 2015)

▪ Re-certified by the American Board of Emergency Medicine (ABEM) as a Diplomate in Specialty of EMERGENCY MEDICINE (January 1, 2016 ---- December 31, 2025)

o Certified by the American Board of Emergency Medicine (ABEM) as a Diplomate in the Sub-

Specialty of EMERGENCY MEDICAL SERViCES (January 1, 2016 ---- December 31, 2025)

OTHER CERTIFICATIONS and NATIONAL STANDARDIZED COURSE COMPLETIONS:

Certified by the American Heart Association (AHA), Texas Affiliate, as an Advanced Cardiac Life Support (ACLS) Center Program Director (1989-1995) and National Faculty for ACLS (1989-1994); Certified as ACLS Instructor (1984). Certified by the American Heart Association (AHA), Texas Affiliate, as an Advanced Cardiac Life Support (ACLS) Provider (2004-2015) Member, National AHA Emergency Cardiovasculer Care (ECC) Basic Life Support (BLS) Subcommittee (1996-2001). Member, National AHA ECC ACLS Subcommittee (1989-1992) and Chairman, Emergency Cardiac Care Committee, Gulf Coast Division (1993-1996). Certified by the American College of Surgeons as an Instructor for Advanced Trauma Life Support (1984 - 2004) and as a Provider for Advanced Trauma Life Support (2006-2010). Designated by the AHA as a Pediatric Advanced Life Support (PALS) Provider (2008-2017). Instructor and Member of the Board of the National Disaster Life Support Educational Consortium for Advanced, Basic &Core Disaster Life Support courses (2003 - present). Completed U.S. Department of Homeland Security – Federal Emergency Management Agency Incident Command System Courses including: IS-100, IS-200, IS-300, IS-400, IS-700, and IS-800B. Completed the National Institutes of Health Office of Extramural Research training course, Protecting Human Research Participants, certificate # 63559, July 25, 2008.

MEDICAL LICENSURES (all current):

State Date of Licensure License Number California Nov. 20, 1978 G-038480 Washington July 20, 1977 001641 Texas Dec. 06, 1982 G2806 Pennsylvania June 22, 1996 MD-059513-L Florida June 18, 2014 ME- 120468

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HOSPITAL APPOINTMENTS

• Parkland Memorial Hospital System Dallas, (2000 – 2016)

• Children’s Medical Center, Dallas, (2000 – present)

• University Hospitals, UT Southwestern (2005-2015)

• University Medical Center at Brackenridge (UMCB) and Seton Hospital, Austin (2013 to 2016) Re-credentialed per routine, 2013 through 2016 (when no longer Chair Emergency Medicine Residency Program at UMCB when UT Southwestern finished affiliation).

• Allegheny General Hospital (Pittsburgh), Senior Attending, 1996-2000. Re-credentialed per routine, 1999 thru 2001 (then left for job in Dallas)

• Texas Children’s Hospital, Consulting Staff (Houston), 1988-99 (new job in Pittsburgh)

• St. Joseph Hospital, Courtesy Staff (Houston), 1982-96 (left for new job in Pittsburgh)

• The Methodist Hospital, Attending (Houston),1982-96 (left for new job in Pittsburgh)

• Ben Taub General Hospital, Attending (Houston), 1982-96 (left for new job in Pittsburgh)

• St. Luke's Episcopal Hospital, Consulting Staff (Houston), 1989-96 (left for Pittsburgh)

SPECIAL ACTIVE APPOINTMENTS

• Emergency Medicine and Trauma Consultant to the White House Medical Unit, 1992- present, (for Bush 41, Clinton, Bush 43 and Obama administrations)

• Special Government Employee (SGE), U.S. Government, 2010 – present

• Consultant to the U.S. Federal Drug Administration, Center for Devices and Radiological Health, 2012- present

• Coordinator and Program Director, U.S. Metropolitan Municipalities 9-1-1 Systems and Federal Agency Emergency Medical Services Medical Directors Coalition (“Eagles Consortium”), 2001-present

• Chair, National Institutes of Health Resuscitation Outcomes Consortium (ROC) Community Consultation Committee for the Dallas region, 2001- present

• Member, Dallas (DFW) leadership team, North Texas Mass Critical Care Plan Community Consultation Committee and Risk Communication Program for North Texas for Pandemics, Nuclear Detonation and other mass disaster incident preparedness, 2010 - present

• Special Advisor to: Federal Bureau of Investigation (FBI),

U.S. Department of Justice (2001-2011) and U.S. Department of Health and Human Services,

National Disaster Medical System (2014 to present) and the U.S. Secret Service, U.S. Department of Homeland Security (1990 to present)

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HONORS:

Elected Phi Beta Kappa, 1972 Elected Alpha Omega Alpha, 1975 Awarded American College of Chest Physicians Scholar Award, 1985 Received City of Houston City Council Resolution of Commendation for Mass

Cardiopulmonary Resuscitation Training, 1985 Awarded 1986 Alumni Achievement Award by Boston University, October 26, 1986.

***Became First Nationally-Elected President, National Association of EMS Physicians, 1986 (and served for 2 consecutive terms; 1988-1990)

Elected to International Scientific Advisory Board, World Association for Emergency and

Disaster Medicine, 1988 Member, U.S. Delegation to U.S.S.R. for Exchange on Emergency and Disaster

Medical Services, 1989 and Special Invited Guest of Honor and Speaker for the Ministry of Public Health of the USSR, 1990.

National Association of EMS Physicians' National Award for Leadership and Excellence

in Prehospital Care, 1990.

****Designated Critical Care Attending Physician to the President of the United States and the six visiting Heads of State for the Economic Summit of Industrialized Nations, Houston, Texas, July 1990.

Received Special Resolution of Commendation from the City of Houston City Council for

Outstanding Service During the Economic Summit of Industrialized Nations, July 1990.

Awarded Communicator of the Year Award by the University of Houston Communications

Alumni organization, 1991.

National Association of EMS Physicians' National Award for Leadership and Excellence in Prehospital Care, 1991 (second year in a row -- only second time recipient).

Recipient of Health Policy Leadership Award from the Houston Area Health Care

Coalition, 1991.

Recipient of Freedom Five Award from the City of Houston, 1992 (for affecting public policy).

Special Citation from the State of Connecticut Senate for International Contributions to

Emergency Medical Services 1992

Co-recipient (Harris County Medical Society) of Pinnacle of Success Award from the American Association of Medical Society Executives, 1992.

Community Builder Award from the Masonic Grand Lodge of Texas, 1992.

Commendation from the United States Secret Service, 1992 following outcomes of National Presidential Conventions.

Recipient of Special Educators' Award from the Texas Department of Health, 1993.

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Elected Inaugural Board Member, for the scientific journal, Academic Emergency Medicine, official journal of the Society for Academic Emergency Medicine (SAEM) and appointed inaugural Associate Editor (direct report to Editor-in-Chief),1994.

Best Oral Clinical Science Presentation Award at the 1994 Annual Meeting of the Society

for Academic Emergency Medicine (co-author/mentor for presenting first author); “Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injury (N Engl J Med October 27,1994;331:1105-1109).

Distinguished Public Service Award from the City of Houston and the Houston Police

Department, 1995.

*** Formally named Emergency Medicine and Trauma Consultant to the White House Medical Unit, 1995 (continues to present).

Special Resolution from City of Houston City Council for Distinguished Service “to the

Citizens of Houston”, 1982-1996; Presented, July 14, 1996.

***Special Proclamation from City of Houston City Council, 1996, naming National Flag Day, June 14th, Dr. Paul Pepe Day in Houston, Texas

Named Special Emergency Medicine Consultant to the National Basketball

Association (NBA) Team Trainers (National Basketball Association Trainers Association), 1997 (continues to present)

***Appointed Commonwealth Emergency Medical Director for the State of

Pennsylvania (State Emergency Medical Services Medical Director), 1998. Appointed Program Director, U.S. Metropolitan Municipalities EMS Medical Directors

Consortium, 1998 (continues to present). Awarded Tuition Scholarship from the Association of Academic Chairs of Emergency

Medicine for the Harvard School of Public Health Program for Clinical Chiefs 1999. ***Received Millennium (2000) Foundation Medal from the Australian and New

Zealand College of Anesthetists Faculty of Intensive Care, May 2000, Melbourne, Australia.

Named National Spokesperson for the American Heart Association regarding new CPR

standards and guidelines, 2000.

****Appointed to the Steering Committee for the National Institutes of Health PULSE Initiative for establishing national priorities in Resuscitation Research, 2000.

Chosen to be Class Speaker for 25th Anniversary of Medical School Graduation for

Alumni Day at the University of California, San Francisco, 2001. Named Consulting Scientist and Fellow, American Association for the Surgery of

Trauma, 2001 ****Appointed Co-Chair for the 2002 National institute of Neurological Disorders and

Stroke National Symposium, “Ensuring the Chain of Recovery in Your Community” and wrote Executive Summary of the Symposium on behalf of the NINDS.

Received Inaugural “Best Doctors in Dallas” Award for Emergency Medicine by “D”

(Dallas) Magazine, 2003 and every year through 2011, 2014, 2015, 2016 and 2017 Subject of Feature Article in the Dallas Morning News, May 1, 2004

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Named Research Decision Editor (Trauma and Resuscitation Research) for the

scientific journal, Critical Care, 2004 throught 2014 Received Outstanding Contributions to Emergency Medical Services Award from the

U.S. Metropolitan Municipalities EMS Medical Directors Coalition, 2004 ****Appointed Inaugural City of Dallas Director of Medical Emergency Services for

Public Safety, Public Health and Homeland Security, 2004

Special Guest Interviewee on The Larry King Live show, Washington, DC, September 23rd, 2005 (see below)

***Received Special Tribute in the United States (U.S.) Congressional Record for

Special Service to the United States in Emergency Medical and Disaster Services, September 29, 2005 ***.

Received Special Commendation and Recognition for Emergency Medical Services

Activities from Mayor Pro Tem, Elba Garcia, Dallas City Council, 2005 ***Received Outstanding Contributions to Emergency Medical Services Award from the

American College of Emergency Physicians (ACEP), September 2005 for lifetime achievement in Emergency Medical Services

Subject of Feature Front Cover and dozen page extended article, Dallas Observer,

November 22, 2005 Received Special “Above and Beyond” Commendation from the Dallas County Hospital

District for efforts during the 2005 Hurricanes Katrina and Rita crises, Feb. 18, 2006 Selected to be a featured Keynote Speaker during the Opening Session for the Annual

Meeting of the International Symposium on Intensive Care and Emergency Medicine (~6,000 attendees) in Brussels, Belgium, March 21st, 2006.

Received the 1st Prize Excellence in Education Award (for content and delivery) from the

International Emergency Cardiovascular Care Update Consortium, June 25, 2006 Chosen to be the featured Keynote Speaker for the Chinese Medical Association Annual Meeting (in Tangshan/Beijing), July 15, 2006

Best Scientific Paper Award for 2006 in the Category of Trauma Resuscitation at the

Annual Meeting of the American Heart Association ReSS Symposium, November 11,

2006, Chicago IL. (Senior Investigator/Mentor on “Lower ventilation rates improve

tissue oxygenation and perfusion during hemorrhagic shock”.)

Chosen as Inaugural Editorial Board Member, for the scientific journal, Disaster Medicine Public Health Preparedness, official publication of the American Medical Association, 2006.

***Entered into Collegium and Academy of Distinguished Alumni of Boston University, College of Liberal Arts (highest honor bestowed upon alumni), May 18, 2007.

Nominated as Texan of the Year (one of 3) by the Dallas Morning News, December 10,

2007 (Section B, Metro, Page 1B and 5B). ***Named a Hero of Emergency Medicine by the American College of Emergency

Physicians (award that recognizes emergency physicians who have made significant contributions to emergency medicine, their communities, and their patients) 2008.

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***Designated with the title of Master of the American College of Physicians (MACP).

Awarded May 15, 2008; for lifetime achievements in the discipline of Internal Medicine.

Chosen to participate as Steering Committee Member, Institute of Medicine Board on Health Sciences Policy Committee on Assessing Medical Preparedness for a Terrorist Nuclear Attack, March, June and August 2008.

Named “Texan of the Week” by the Texas State Networks Broadcasters, March 9, 2009. Received “Pre-eminent Innovator in EMS” award from the National Academies of

Emergency Dispatch, April 29, 2009.

Cited as “Alumnus at the Forefront of Science/Research” by the Choate School, 2009

(secondary school)

Received “2010 Innovator in EMS” award from the EMS Today National Conference, March 3, 2010, Baltimore

Cited as “The Change Agent” by the Journal of Emergency Medical Services, April

2010.

****Selected as National Finalist (one of four) for the Emergency Medicine Foundation (EMF) 2010 Emergency Department Director of the Year Award

Recognized in Special Article in Texas EMS Magazine for longstanding contributions to EMS, November-December 2012

Selected to Co-Chair the International Blue Ribbon Scientific Panel and Global Study Section on Clinical Neuroprotection (with Nino Stochetti from Milano, Italy); designed and organized the meeting; conclave was attended by two-dozen of the world’s leading scientists in the field of neuroprotection including Principal Investigators of several large scale nationally funded research consortiums; convened in Brussels, Belgium, March 15th through the 18th, 2013; later selected to construct the Executive Summary and Recommendations of the proceedings.

Selected to be a featured Keynote Speaker at the Opening Session for the Annual Meeting of the International Symposium on Intensive Care and Emergency Medicine (~6,000 attendees) in Brussels, Belgium, March 19th, 2013.

**** Selected as Finalist/Presentor of the Best Paper Award (top ten of 800 papers) for the International Symposium on Intensive Care and Emergency Medicine (6,000 attendees), Brussels, Belgium, March 19, 2013

Named Texas Super Doctor in Critical Care Medicine, 2011 through 2016 Texas Monthly, December 2011, 2012, 2013, 2014, 2015, 2016 and 2017

*****Recipient of the Society for Academic Emergency Medicine (SAEM) “Excellence in Research Award” for lifetime achievements in scientific investigations, May 12, 2014

***** Featured as a “Notable” Alumnus in the field of Medicine by the Choate School, Wallingford, Connecticut (along with others such as John F. Kennedy and Adlai Stevenson in the Government category and Michael Douglas, Edward Albee and Glen Close in the Arts and Entertainment category), January 2015 Named to (new) Position of Director, Regional Out-of-Hospital Mobile Care Systems and Disaster/Event Preparedness, Office of the Executive Vice President for Health System Affairs, the University of Texas Southwestern Medical Center, Dallas

Named Science Officer for the Canadian Institutes of Health Research (CIHR) ’ as a keymember of CIHR study sections that evaluated the quality and priority scoring of scientific grant applications and write the executive summary on behalf

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of the CIHR (2015) Co-Recipient of the Ron J Anderson National Award for Public Service by the U.S. Metropolitan Muncipalities 9-1-1 System (EMS) Medical Directors Consortium as an original Founding Member (2002) of the National Disaster Life Support (NDLS) family of disaster and all-hazards training courses, now considered the “gold standard” in training health care providers in disaster medicine and public health threat mitigation by professional groups such as the American College of Emergency Physicians (ACEP). ****** Designated and inducted as Master of Critical Care Medicine (MCCM) by the Society of Critical Care Medicine (2016) for achievements as a distinguished leader of international stature, personal character, eminence in clinical practice and on-going outstanding contributions to research and education in the field of critical care

Recipient of the Outstanding Leadership in Emergency Medicine award from the University of Maryland, Baltimore, Maryland, October 2016 ****** Inaugural Designee for the Designation of Fellow of the Academy of Emergency Medical Services (FAEMS), November 2016 ***** Co-Recipient, State of Florida EMS Provider of the Year, from the State of Florida

Department of Health for accomplishments over the prior year achieved by the Coral Springs Fire Department, Coral Springs, FL (serving at the CSFD Medical Director for Research, Education and Special Operations). Presented in Orlando, July 11, 2017

MAJOR PROFESSIONAL ACCOMPLISHMENTS (10 examples)

• Appointed and retained as Emergency Medicine and Trauma Consultant to the White House Medical Unit for past four presidential administrations, serving Drs. Mohr (Bush 41), Mariano (Clinton), Tubb (Bush 43), Kuhlman and Jackson (Obama) with on-going active support in advanced training and requested counsel for best practices.

• Founded and became first nationally-elected President of the National Association of EMS Physicians (NAEMSP), now the lead professional organization for the new ABMS sub- specialty of Emergency Medical Services (EMS) and was the first prototype full-time EMS physician (Director of Emergency Medical Services System in Houston --1980s); Sample refs: Medical Direction of Emergency Medical Services Systems. Emergency

Medical Services: Clinical Practice and Systems Oversight, Textbook of the NAEMSP, Kendall-Hunt Publications 2009; pp 22-52; Crit Care Med Sept.1993;21:1279-1286.

• Published original descriptions, formal definitions and metrics for the Auto-PEEP phenomenon (Am Rev Resp Dis, 1982; 126:166-170) and the “Sepsis Syndrome” (systemic signs of infectious/inflammatory process with deleterious systemic response) which became a prototype for subsequent descriptions and research in systemic inflammatory response syndrome concepts. Also, the first prospective study of defined ARDS risks (Am J Surgery 1982; 144:124-130 & NEJM, August 5, 1984;311:281-286);

• Continued to win numerous “best scientific paper” awards/nominations from a myriad of international scientific assemblies and congresses (eg, estrogen in burns and head injury repair; detrimental effects of ventilation in post-traumatic brain oxygenation); also, post-auto-PEEP work on detrimental hemodynamic effects of ventilation led to profound changes in ventilatory practices for both trauma and cardiac arrest patients, including re-appraisal of rescue breathing in CPR and eventually “compressions-only” CPR. (e.g., J Trauma 2003;54:1048-57; Circulation 1997; 6:2102-2112)

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• Senior/Executive Summary author for the original American Heart Association “Chain of Survival” paper for cardiac arrest and original National Institutes of Health/NINDS “Chain of Recovery” publication for stroke. Circulation 1991; 83:1832-1847; NINDS publication; Sept 2003; pp. v–vii and the Resuscitation Task Force for the 1st World Congress on Drowning (Springer-Lager, Heidelberg, 2005 pp.314-323).

• Designed and published the first (prospective) clinical trials for interventions for prehospital trauma resuscitation (PASG / deferred IV fluids) in the emergency medicine literature (and other sites) as well the first multi-center trials for out-of–hospital cardiac arrest. (e.g., Ann Emerg Med 1987; 16:653-658; N Engl J Med Oct 27,1994;331:1105-1109; N Engl J Med 1992;327:1051-1055; J Trauma 1994;36:131-134; Ann Emerg Med 1986;15:1406-10: N Engl J Med October 17, 2002, 347:1242-7).

• Was a founding steering committee member for the 2000 NIH PULSE Initiative that led to the NIH Resuscitation Outcomes Consortium (ROC); having been involved in the great majority of U.S. prehospital clinical trials for trauma resuscitation published over the prior two decades, his pivotal early role with the ROC also led to his academic unit and a dozen other major sites being formally designated in 2004 through 2015 as federally- supported resuscitation research centers for conducting clinical trials with current on- going funding; continued to serve as a ROC steering committee member and Co-

Principal Investigator through 2015 (e.g., Acad Emerg Med 2002;6:613). Was also one of the main reviewers for the NIH SIREN Hub grant applications 2016

• Among numerous prestigious awards (e.g., alumnus of the year from undergraduate school, Master of the American College of Physicians; and Master of Critical Care Medicine); was cited as “the most accomplished emergency medical services physician of our generation” and named a “Hero of Emergency Medicine” by peers at ACEP; also honored as the “Preeminent Innovator in Emergency Medical Services” and selected 2009 EMS Innovator by the Journal of Emergency Medical Services. Also selected as a finalist for the Emergency Medicine Foundation’s 2010 national Emergency Department Director of the Year Award; was honored in 2014 with Society Academic Emergency Medicine “Excellence In Research Award” for lifetime accomplishments in scientific investigation and advocacy and RJ Anderson National Award for Public Service (co-founder of NDLS courses in 2002).

• Due to leadership roles in the response to Hurricane Katrina & other major disasters, as well as pioneer efforts in evidence-based approaches and safety advances in 9-1-1 systems, was cited in the U.S. Congressional Record for courage and lifetime achievements in research and public service; also honored by U.S. Surgeon General for the same.

• In addition to academic achievements, also simultaneously served as a high-level state and/or municipal employee: Currently serves as City of Dallas Director of Medical Emergency Services for Public Safety, Public Health & Homeland Security as well as EMS/Public Safety Medical Director for Dallas County. Previously served as Emergency Medical Services System Director for Houston (1982-1996); Commonwealth of Pennsylvania Emergency Medical Director (1998- 2000) and also assistant (Medic I field physician) for the Seattle EMS medical directors (1977-1982), a position in which the previously research focus on the earliest possible interventions (to optimize quality of care, patient safety and outcomes for critical illness and injury) was first honed and published. Also remain a longstanding Special Government Employees for the U.S. Department of Health & Human Services. In addition, now serve as Medical Director for Research, Education and Special Operations for Palm Beach County Fire Rescue, West Palm Beach Fire Rescue, Coral Springs Fire Rescue, Davie Fire Rescue and Broward Sheriff’s Office Fire Rescue, including Fort Lauderdale International Airport, Port Everglades, Broward County, FL

PROFESSIONAL ORGANIZATIONS

Association of Academic Chairs of Emergency Medicine – Active Emeritus Member; awarded tuition Scholarship from the Association to attend the Harvard School of Public

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Health Program for Clinical Chiefs (PCCS), 1999; (Member; 1997-2001 and 2009-2014 and 2016- present)

American Association for the Surgery of Trauma -- Member, Fellow, and Consulting Scientist (2001-present); Runner-Up for Best Paper award 2001

American College of Chest Physicians (Fellow, FCCP; 1982-2008) Recipient of ACCP Scholar Award, 1985; Special Consultant Task Force on Mass Critical Care and Alternate Standards of Care (risk communication and local management expert)

American College of Critical Care Medicine (Fellow, FCCM; 1990-2015; Elected to Mastership (MCCM) in 2015 and inducted in 2016

American College of Physicians (Fellow, FACP; 1984-present); Elected to Mastership (MACP), 2008 for lifetime achievements in Internal Medicine.

American College of Emergency Physicians (Fellow; FACEP); (1986-present) Founder and co-Director of the ACEP Advanced EMS Medical Directors’ Course; Winner of ACEP 2005 National Emergency Medical Services Award; received “Hero of Emergency Medicine” Award in 2008; Nominee for 2012 Award for Research; Faculty member, Emergency Medicine Basic Research Skills Seminar (EMBRS) 2001-2006; Member, Public Relations Committee 2001-2012. Former Member, Task Force on AIDS; Former ACEP Liaison to U.S. FDA Task Force on Defibrillator Use; Member, Research Section; Member, Pediatric Emergency Medicine Section; Past Member, EMS and Disaster Medicine Sections; Former Member, EMS Committee; Past Member, EMS Coalition; Former Member, Research Committee; Former Member, International Affairs Committee; Founding Member and Board of Director Liaison Alternate, Event Medicine Section (2016-present).

American Heart Association, Member and Co-Author of the 1994 Textbook of Advanced Cardiac Life Support; Past Member, National Emergency Cardiac Care Committee (ECC), Subcommittee on ACLS (1989-1993) and Member, Subcommittee on Basic Cardiac Life Support (1996-2003); Moderator, Presenter and Guidelines Developer for 2000 International guidelines for CPR and ECC; Special Consultant for 2005 and 2010 Guidelines development; Named National Media Spokesperson for Roll-out of 2000 Guidelines on CPR and ECC; Named National Spokesperson for Media for the American Heart Association National CPR Weekend Event (April 28-29, 2001), Co-Author of 2000 Guidelines on Basic Life Support; Co-chair and National spokesperson, National CPR weekend (2000-2001); Member, Operation Heartbeat Initiative, Dallas Division (2001-2005).

American Medical Association (1984-present); Member, Steering Committee, National Disaster Life Support (NDLS) family of courses; Executive Committee Member, AMA National Disaster Life Support Educational Consortium; Former Delegate, Commission on Emergency Medical Services and Faculty, Annual Health Care Reporting Conference; Moderator for the 2009 AMA-Centers for Disease Control and Prevention (CDC) 3rd National Congress on Health System Readiness, Washington, DC.

Dallas County Medical Society, Member, Stroke Center Committee and Board of Health (2000-2004); Leadership group for Mass Critical Care and Resuscitation Research Community Consultation Committees (2011-present); Member Community Emergency Response Committee (2016-present).

International/National Academy of Emergency Dispatch (Fellow, FACEMD); Member, College of Fellows (1991-present); Senior Author on 2005 international position paper on dispatcher instructions for cardiopulmonary resuscitation (CPR). Received special, one-time life-time achievement award, “Preeminent Innovator in EMS”, April 29, 2009 from the IAED.

National Association of Emergency Medical Services Physicians (Fellow, FAEMS); Member,1985-present; Past National President (3 consecutive years); Former Chair, Public Relations Committee; Past Chair, International Affairs Committee; Former Member, Database and Journal Editorial Boards; and Past Chair, Program Committee; Past-Member, Task Force on Health Care Legislation; Past-Head, National Media Relations; Co-Founder and Faculty, National EMS Medical Directors Course and Practicum (1989-present) and Inaugural Faculty Member for Advanced Medical Directors Course (2009-present). Inducted as inaugural Fellow of the Academy of Emergency Medical Services (FAEMS).

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Society for Academic Emergency Medicine (1983 [as UAEM] to present); Associate Editor and Inaugural Editorial Board Member for the Journal (1994-2000); Member, Political Affairs Committee (1997-1998); Member, Publications Committee (1997-1998); Former Chief Delegate to AMA Commission on EMS; Former Steering Committee Member, EMS Educator's Ad Hoc Committee; Former Member, EMS Committee (1995-1997); Former Member, Annual Program Committee (1993-1996); Former Member, Injury Prevention Committee; Former Member, CPR Committee; and Former Member, Research Committee Task Force on Informed Consent; special presentor on mentoring careers. Winner, SAEM “Excellence in Research Award” for lifetime accomplishments in scientific investigation and advocacy.

Society of Critical Care Medicine (1981-present); Member, Emergency Medicine Section; Member, Task Force on Disaster Medicine; speaker annual meeting 2007 and 2012 and scientific presenter, 2017 and named Master of Critical Care Medicine (MCCM) in 2016.

Texas College of Emergency Physicians; Member, Governmental Affairs Committee (2001-present; Former Key Legislative Contact; Former Member, Education Committees.

Texas Medical Association; Current and Former Member and Former Consultant, EMS and Trauma Committee (1982-1996 and 2000-2002)

Florida Medical Association, Member (2014- present)

U.S. Metropolitan Municipalities’ EMS Medical Directors Consortium (the “Eagles Coalition”), Inaugural Member and Program Director (1998-present); ran national meetings 14 consective years including main winter conclave and numerous satellite meetings and also service as point person liaison to White House National Security Staff, U.S. Department of Health and Human Services and U.S. BioWatch program.

Some Previous Memberships:

Allegheny County Medical Society (Former Member); Member, Committee on Bio-Ethics; Member, Communications Committee (1996 - 2000)

American Heart Association, Houston Division; Former Member of the Board of Directors and Former Chairman, Emergency Cardiac Care Committee (1992-1996).

Harris County Medical Society; Past Vice-Chairman, Committee on Emergency Medical Services and Member, Trauma Commission and Injury Prevention Committee (1982-1996).

Houston Society of Emergency Physicians; Former Member and Regular Presenter for Monthly Meetings (1993-1996).

National Association of State EMS Officials; Associate / Medical Director Member (1998 -present);Guest Speaker at 1999, 2000, 2002, 2003, and 2006 Annual Meetings; Inaugural Steering Committee Member for the Council of State EMS Medical Directors; 2006 – 2007. World Association for Emergency and Disaster Medicine; Former Member, Executive Committee; Member, International Scientific Advisory Board and Faculty, Sixth and Seventh World Congresses (1985-1993)

SOCIETY FELLOWSHIPS:

Master, American College of Physicians (MACP), 2008 Master, American College of Critical Care (MCCM), 2016 Fellow, American College of Physicians (FACP), 1985 Fellow, American College of Chest Physicians (FCCP), 1984 Fellow, American College of Emergency Physicians (FACEP), 1988 Fellow, American College of Critical Care (FCCM), 1990; Fellow, American College of Emergency Medical Dispatch (FACEMD), 1991 Fellow, Academy of Emergency Medical Services (FAEMS), 2016

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PROFESSIONAL COMMITTEES and ADMINISTRATIVE SERVICE: Current Services: Local: Director, City of Dallas Medical Emergency Services for Public Safety, Public Health and Homeland

Security as well as related research (city employee position reporting to Dallas City Manager, Mayor and City Council) providing medical oversight of public safety functions including counsel to Dallas Fire-Rescue Department, Texas Task Force 2 Urban Search and Rescue Team, Dallas Police Department (DPD), DPD Tactical Division, Aquatics Division, Dallas Love Field (airport) and AED placements.

Medical Director for Special Operations, Dallas-Fort Worth (DFW) International Airport Medical Director, Dallas County EMS System (unincorporated Dallas County) Committee Chair for the Dallas Area Community Consultation Committee for Exception to Informed Consent Studies and Mass Critical Care

Recent Past Local Services:

Chair Emeritus, Emergency Medicine (EM) UT Southwestern 2000-2014; university-wide leader in EM

for UTSWMC and PMH; Provide Supervision for approximately 72 Faculty members, 70 Residents and Fellows, EM Residency (57 EM residents over 3 years), Toxicology Program (13 faculty, Fellowship, Poison Center and Clinical Services = 90,000 annual consultations), Clinical Services at PMH Emergency Center (~145,000 high-acuity/ non-urgent care annual adult visits); EM Research Programs (including CDC and NIH designated Centers) and surrounding EMS System (~15 cities, 250,000 annual incidents). Oversight of recruitment, uninterrupted clinical staffing (550 shifts per month), budget (> $20 million operations), grants management and stewardship of > $10 million (multi-year funding), initiatives for revenue enhancement, strategic planning, general administration and final internal decision making, educational programs for the EM residency, the medical school (including medical student ACLS) and the community at large as well as faculty and staff evaluations, disciplinary and human resource issues, policy and procedures, institutional compliance completion, faculty development and practice performance monitoring. Also, provides reciprocal duties for other institutions (promotion letters, credentialing, professional society administrative surveys).

Chair Emeritus, Emergency Medicine (EM) Residency Program UTSWMC at Brackenridge Hospital

2012-2014, Austin TX; Provides academic supervision for approximately 38 Faculty, 8 EM Residents per year in a three year program as wells as fellowships and other academic programs and provide direction and guidance to residency and clinical directors as well as research director and other section chiefs;report to Regional Dean for the University Medical Center at Brackenridge (UCMB), Dr. Susan Cox (2010- 2014)

National Services: Emergency Medicine Consultant & Resuscitation Training Coordinator, National Basketball Association (NBA) Trainers Association (1997-present). In addition to CPR and AED recertification for approximately 75 head trainers, assistant trainers and strength coaches, provide direct input into emergency action plans for NBA teams.

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Emergency Medicine and Trauma Consultant to the White House Medical Unit (1994 – 2015), serving the President to the Physician and the Director of the White House Medical Unit in terms of updated training, new initiatives and other related issues. Also facilitates keeping WHMU in touch with the jurisdictional medical directors of the nation’s largest cities and medical directors for EMS in key federal agencies (“Eagles Coalition”). Consultant to ABC News for Emergency Medicine and Trauma (ABC World News Tonight, Nightline and 20/20) (1995-present). Editorial Board, National Disaster Life Support (NDLS) Courses (ADLS, BDLS, CDLS), 2002-present and Board of Directors, National Disaster Life Support Foundation for the NDLS Courses (ADLS, BDLS, CDLS), 2003-present. Executive Committee Member, National Disaster Life Support Educational Consortium (NDLSEC) for the ADLS, BDLS, CDLS, 2006-2012 and now the independent NDLSEC, 2012-present. Consultant to U.S. Department of Homeland Security (DHS) Office of Domestic Preparedness, Center for Domestic Preparedness (CDP), 2003-2004 and current ad hoc consultant to DHS (2003- present). Co-Founder and Faculty Member, National EMS Medical Directors Course & Practicum (1989-2013). Inaugural (& continuing Faculty Member), National Association of EMS Physicians Advanced Topics in Medical Direction Course (2010-present). Founder & Program Director for the American College of Emergency Physicians (ACEP) Advanced EMS Practitioners’ Forum and Workshop (2009-present). Member, Planning Task Force and Co-Chair, Ventilation Panel for the National Institutes of Health (NIH), Federal Drug Administration (FDA), and Department of Defense PULSE Initiative (Post-Resuscitative and Initial Utility in Life-Saving) efforts (2000-2004) and subsequent Executive Committee Member and site Co-Principal Investigator for the NIH Resuscitation Outcomes Consortium (ROC), the National Institutes of Health (NIH) 10-Site North American Clinical Trials network for Trauma and Cardiac Arrest Resuscitation studies. Medical Director for Research, Education and Special Operations for:

• Palm Beach County Fire Rescue (FL); 2015 - present

• City of West Palm Beach (FL); 2016 – present

• City of Coral Springs (FL); 2015 – present

• City of Davie Fire Rescue; 2017-present

• Broward County Sheriff’s Office, Broward County EMS; 2017 - present Overlapping National and International Scholarly Activities:

• Immediate Past Research (decision) Editor for Trauma, Disasters, Emergency Care and Resuscitation (2004-2014) and Member, Editorial Board, Critical Care (2004 – 2015) [Impact Factor 5.04]

• Editor for Avoiding Common Prehospital Errors. Lawner, Slovis, Fowler, Pepe, Mattu (eds), Lippincott, Williams & Wilkins, 2011-present

• Editorial Board Member and Reviewer, Resuscitation (2002-2014)

• Editorial Board Member and Reviewer, ICU Management (2014-present)

• Inaugural Editorial Board Member, American Medical Association scientific journal, Disaster Medicine and Public Health Preparedness (2006- 2011)

• Member, Editorial Board for Prehospital Emergency Care (2002-present)

• Editorial Board Member, Emergency Medicine Reports (1997-present)

• Reviewer, Critical Care Medicine (1990-2014).

• Reviewer, American Journal of Emergency Medicine (1989-2014).

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• Reviewer, Journal of the American Medical Association (1990-2014).

• Reviewer for Resuscitation Studies, New England Journal of Medicine (2010-present) SPECIAL ACTIVITIES: Formal Evaluations, Consultations and/or Site Visits of EMS Systems (1984-present) in: Australia (New South Wales and Queensland); New Zealand (Dunedin, Tapanui and Queenstown); Pittsburgh, PA (1984); Seattle, WA; New York City, NY; San Francisco, CA; Dallas, TX; London, England; Salt Lake City, UT; San Diego, CA; Nairobi, Kenya; U.S. Virgin Islands; Minneapolis, MN; Albuquerque, NM; Ravenna and Bologna, Italy; Maryland State EMS System; Baltimore County EMS System; Anchorage, AK; Soldotna, AK; Southern Connecticut EMS System, New Haven (1989); Los Angeles, CA; Moscow, U.S.S.R. (1989); Leningrad, U.S.S.R.; Beijing, China (1989); Taipei, Taiwan; Hong Kong; Montreal, Canada (1991); Paris, France (1991); Athens, Greece; Edinburgh, Scotland; Washington, D.C.; Patras, Greece (1991); Boston, MA; New York City, NY (1992); Las Vegas and Clark County, NV; Miami, FL; Indianapolis, IN; Edmonton, Canada; Pittsburgh, PA (1993); Miami, FL (1993); Maryland Institute for Emergency Medical Services Systems, Baltimore, MD (1994); Prince Georges County, Maryland (1994); Baltimore City (1994); Richmond, VA (1994); Cleveland, OH (1994); Sacramento, CA (1994); Kansas City (1995); Honolulu, Oahu and Kauai (1995); Cologne, Germany (1995); New Haven, CT (1995); Sydney, Australia (1996); Hobart, Tasmania (1996); Auckland and Queenstown, New Zealand (1996); Lisbon, Portugal (1996); State of Qatar (1997); City of Philadelphia (1998,1999); Cities of Bethlehem and Allentown (1998); Boston (1998); Phoenix (1998); Harrisburg (1999); Washington, D.C. (2000); SAMU (EMS System) of Paris, France (2000 and 2001); Trauma Center, Vienna, Austria (2001), Los Angeles EMS (2002), Seattle EMS (2004), Nashville, (2004); Houston EMS and dispatch (2004), San Francisco EMS (2004); New York City Fire and EMS (2006), Austin EMS (2006) Colorado Springs Fire (2007); Seattle (2008) and Houston (2008); Tulsa (2009), Washington, DC (2010), San Diego (2010), Cincinnati (2010), Oklahoma City 2010, several cities in India (2010), Seattle (2011), Roeselare (Flanders), Belgium (2011), Bangkok, Thailand (2011), Omaha (2012), San Francisco (2012), London (UK) pre-Olympics (2012), Barcelona (2012); San Diego (2012); Broward County EMS (2013 and 2014), Las Vegas (2013 and 2014); Fort Lauderdale Fire Department (2014 and 2015); Dublin Ireland (2017); Paris, France (2017); London, UK (2017) 1987, 1990 Special Consultant to the National Aeronautics and Space Administration (NASA)

For Emergency and Ventilatory Equipment, Protocols and Planning for the Space Shuttle, Space Station and Crew Emergency Rescue Vehicle.

1988 Special Presenter -University of Texas Health Policy Institute Hearings on

Technological Extension of Life. 1989 Site Visitor, Critical Care Fellowship Programs for Accreditation Council on Graduate Medical Education. 1990 Designated Critical Care Physician for Heads of State during the Economic Summit of Industrialized Nations, July 1990. 1990 & 91 Special Guest of Honor and Speaker for the USSR Ministry of Health International Conference on Disaster Medicine 1992 Director of Emergency Medical Services for Republican National Convention, 1992. 1992,1999 Panel Member & Guest Speaker, American Heart Association. Emergency Cardiac

Care Committee 2000 Panelist and Panel Chair, American Heart Association. Emergency Cardiac Care

Committee National Standards Conferences, Dallas, TX. 1992 Special Guest Faculty, U.S. Conference of Mayors, Houston, TX. 1993 Member/Guest Speaker, U.S. Secret Service Emergency Physicians Advisory Panel

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1993 Guest Speaker, International Sister Cities Conference, Houston, TX. 1993 Keynote Speaker, for the Combined Meeting of the Society for Academic Emergency

Medicine and the Emergency Medicine Research Society of the United Kingdom, Trinity College, Cambridge, England, September 1993.

1994 Special Guest of Honor and Keynote Speaker for Emergency Medicine Week in

Japan; Special Guest of the U.S. Embassy and Japan EMS Physicians Association, Tokyo and Nagoya, Japan.

1995 Special Guest of Honor for the Cologne, Germany, Emergency Medical Services

Program. 1996 Special Guest of Honor for the New South Wales Ambulance Service (Australia) and

the St. John's Ambulance Service (Auckland and Queenstown, New Zealand) 1996, 1999 Special Guest Speaker for Wolf Creek IV and New Era of Cardiopulmonary

Resuscitation Conferences, Palm Springs, CA. 1996 Special Consultant to ABC News (ABC World News Tonight, Nightline and 20/20) for 1997 Emergency Medicine (now on-going). 1996 Panel Chairman and Spokesperson, National Stroke Symposium sponsored by the 1997 National Institute for Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Arlington, VA. 1997 Guest Speaker and Panelist, Ministry of Health, State of Qatar, Doha, Qatar. 1998-present Host and Course Director, Annual EMS State of the Science National Conference 2000 National Media Spokesperson, American Heart Association for both new CPR

Guidelines and National CPR Weekend. 2000 Special Guest Speaker and CPR/ AED Trainer for U.S. Surgeon General (David Satcher, MD) and his Senior Staff. 2000 Speaker, National Institutes of Health Workshop on Post-Resuscitative Care and Initial

Utility in Life-Saving. 2001 Special Guest Speaker for Brazilian Congressional Committee on Public Access Defibrillation, Dallas, TX 2002 Co-Chair, National Institute of Neurological Disorders and Stroke (NINDS) National Symposium, “Ensuring the Chain of Recovery in Your Community”, 2002. 2003 Special Guest Speaker for U. S. Surgeon General Richard Carmona, Washington, DC and Bryan, TX. 2003 Special Guest Speaker for the American Medical Association 9-1-1 Forum

2005 Special Consultant to the Secretary of Health, State of Louisiana and the Louisiana State Health Officer during Hurricanes Katrina and Rita, August – September, 2005. 2006-2014 Special Consultant on medical security and event medicine for various entertainment tours security and their crews (e.g., The Rolling Stones, The Police, Madonna, U2) 2008 Committee Member, Institute of Medicine Board on Health Sciences Policy Committee on Assessing Medical Preparedness for a Terrorist Nuclear Attack – April – August 200 2008 Committee Consultant, Institute of Medicine Board on Alternate Standards of Care in

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Major Disasters, Pandemics and Nuclear Attack 2011 2010 Special Consultant and Keynote Speaker for the 2010 INTEM Congress, the nation of India’s International Congress on Emergency Medicine, Ahmedabad, India, Nov 2010

2011 Special Consultant and Keynote Speaker for the 2011 ACEM Congress, the Asian Congress on Emergency Medicine, Bangkok, Thailand, July 2011

2012 Special Consultant and Keynote Speaker for 2011 Trauma Conference, the University of Barcelona School of Medicine Congress on Intensive Care, Barcelona, Spain, May 2012

2012 Special Consultant/Keynote Speaker for 2012 ACEM Congress, Dublin Ireland, June 2012

2013 Chair of the Neuroprotection International Scientific Roundtable and Opening Session Plenary Speaker for the 2013 International Symposium on Intensive Care and Emergency Medicine (ISICEM) Brussels, Belgium (6,000 attendees) 2014 Panelist for the American College of Chest Physicians (ACCP) series of publications on Mass Critical Care (Chest October 2014) 2015 Final reviewer for the Institute of Medicine (IOM) 400-page report on out-of-hospital cardiac arrest entitled: “Needless Death and Disability – Treatment of Cardiac Arrest in the United States” 2015 Science Officer, Canadian Institutes of Health Research (CIHR) on Community Health Clnical trials initiatives within the Institute of Circulatory and Respiratory Health 2016 Planning Committee Member, Moderator and Presenter for the National Academies of Science, Engineering and Medicine (NASEM) symposium on implementing strategies for treatment of and improving survival in cardiac arrest

2016 Reviewer National Insitutes of Health, SIREN Grant applications

Former Institutional Responsibilities: MCP*Hahnemann University - Administrative:

Member, Executive Committee of the Faculty (1996-1998) Member, Task Force on the 1997 Clinical Research Conference (1996-1997) Member, Task Force on Patient Access to Care (1996-1997) Member, University Leadership Committee (1996-1998) Member, Committee for the University (as medical staff representative; 1998 - 1999) Allegheny University Hospitals, Allegheny General - Administrative:

Chairman, Department of Emergency Medicine (Emergency Departments, Allegheny General and satellites; Emergency Medicine Residency; LifeFlight; Life Support Training Services; Out-of-Hospital Medical Direction; and Center for Violence and Injury Control) (1996-2000) Member, Executive Committee of the Medical Staff (1996-2000) Member, Corporate Management Committee (1996-2000) Member, Injury Prevention Program (1996-2000) Member, Chief Executive Officer’s Advisory Committee (1996-2000) Member, Trauma Committee (1996-2000) Member, Department of Surgery Executive Committee (1996-1997) Member, Quality Assurance Committee (1996-2000) Medical Director, Injury Prevention Program (1997-1998)

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Member, Quality Council (1997-1998) Member, Medical Staff Committee on Public Relations (1998-2000) Baylor College of Medicine - Administrative: Director, Baylor College of Medicine Center for Resuscitation Training (Accredited by the American

Heart Association as a designated center for Advanced Cardiac Life Support; 1989-1995) Member, Baylor College of Medicine, Dept of Medicine ACLS Committee (1985-96) Member, Dean's Task Force on Emergency Medical Services Training (1990-1996) Member, Baylor College of Medicine Institutional Safety and Security Committee (1984-1995) Member, President's Task Force on ACLS Instruction for Medical Students (1990-1994) Special Consultant to NASA for Health Maintenance Facilities on Space Shuttles and the Space

Station, as well as the Crew Emergency Rescue Vehicle (CERV) (1987, 1990-1993) Member, Library Committee, Harris County Hospital District Medical Staff (1984-1990)

Former Extramural Responsibilities: Allegheny University Hospitals, Allegheny General Hospital - Local Services: EMS Outreach - Weekly site visits, ride-along and lectures to regional EMS programs (1996-2000). Base Facility Director, On-line medical command services for Eastern Allegheny County Prehospital

Care Services (1996-2000). Member, Task Force on Air Medical Alliance for Western Pennsylvania (1996-2000). Medical Director, Advisory Council on Trauma Prevention, Allegheny County (1997-2000). Member, Greater Pittsburgh Youth Crime Prevention Council (1997-2000). Baylor College of Medicine - Local Services Medical Director, City of Houston/Harris County Hospital District Emergency Medical Services Base

Station (1982-1996); Supervisor & Instructor for 20 (rotating) physicians and paramedics (60/yr). Medical Director, Houston Fire Department (1982-1996); Supervised and trained 2,400 EMS

personnel through 24 EMS paramedic supervisors, four physicians and six nurses. Medical Director, Houston Fire and Ambulance Dispatch Office (1982-1996); supervised medical

activities of 60 9-1-1 medical dispatchers. Medical Director, City of Houston Fire Department First-Responder Program; trains 2,200 firefighters,

police, U.S. Secret Service Agents annually (1988-1996). Director, Medical Education, Research and Quality Assurance Staff, City of Houston EMS Division

(four physicians, flight nurses, 12 paramedics, EMTS and administrators); reviews, analyzes and provides feedback on 190,000 patient records annually (1982-1996).

Director, City of Houston Emergency Medical Services Medical Management Conference Program; provided interactive workshops & didactics for 300 paramedics & EMTs each month (1985-96).

Previous COMMUNITY SERVICES: Former Local: Member, City of Pittsburgh Youth Crime Prevention Task Force (1997-2000) Member, Pittsburgh Area Mass CPR Training Task Force (1996-1998) Member, American Heart Association, Allegheny County Affiliate, Committee for Stroke and AED Outreach Initiatives (1999-2000) Member, Allegheny County Medical Society Communications Committee (1996-2000) Allegheny County Medical Society Bio-Ethics Committee (1996-2000) Member, EMS Institute Medical Directors’ Committee (1996-1998); ex-officio member (1998-2000) Member, Advisory Council on Trauma, Allegheny County (1996-2000) Director, City of Pittsburgh Board of Education Initiative for Community-Wide School CPR Training (1997-2000)

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Founder, City of Houston Citizens' CPR Task Force (1983), Chairman (1983-1987), Medical Director (1983-1996) Annual Mass CPR Training Event at the Astrodome, Houston Medical Director and Founder, City of Houston/American Heart Association Annual Infant and

Child CPR Mass Training Event (1993-1996), George R. Brown Convention Ctr, Houston Chairman, Emergency Cardiac Care Committee, Gulf Coast Council American Heart Association (1992-1996) Chairman, Committee on ACLS for American Heart Association Greater Houston Area (1991-1992)

Vice-Chairman, Harris County Medical Society Committee on Emergency Medical Services (1983-1993) and Member, Subcommittee on Hospital Transport Diversions (1989-1990)

Member, Board of Directors, Texas Department of Health Regional Advisory Council for Trauma -Southeast Texas Trauma Advisory Council (1993-1996)

Board Member, Greater Houston EMS Council (1990-1995) Board Member, American Heart Association Gulf Coast Council (1994-1996) Member, EMS Advisory Committee; Houston Community College (1982-1996) Member, Harris County Medical Society Trauma Care Commission (1988-1996) Member, Harris County Medical Society Injury Prevention Committee (1991-1996) Member, Disaster Victims' Information Committee of Harris County (1990-1996) Member, Board of Directors for the Save A Life - Prevent a Drowning Coalition (1992-1996) Medical Expert, Channel 8, WFAA TV (ABC) Weekly Live Spot (2002-2005) Medical Expert, Channel 11, KTVT TV (CBS) Weekly Live spot (2005-2006) Physician Member, Disaster Medical Assistance Team TX-4, Dallas-Fort Worth Area, U. S. Department of Health and Human Services Former State/Regional: Member, Pennsylvania State Department of Health Regional Emergency Medical Services Institute

Medical Directors’ Committee (1996-2000) Member, Pennsylvania Chapter, American College of Emergency Physicians (1996-present); ex-officio

member of the EMS Committee (1998-2000). Emergency Medical Director, Commonwealth of Pennsylvania (1998-present)

Ex-Officio Member, State of Pennsylvania Emergency Health Services Council, Medical Advisory Committee (1998-2000)

Member, Board of Directors, Trauma Advisory Council, Texas Health Department Region Q (1993-1996) Member, Texas Chapter, American College of Emergency Physicians Task Force on Liability Issues

(1989-1990); Key Legislative Contact (1990-1991) and Member, Committee on EMS (1990-1996); Member Program Committee (1995-1996); Faculty Member, Texas EMS Medical Directors' Course (1992, 1994 and 1996)

Member, Texas State Department of Health EMS Medical Director's Steering Committee, Bureau of Emergency Management (1983-1991)

Rotating Presenter, Texas Department of Health Council for the Advancement of Rural Education (1992-1996)

Member, Texas Medical Association Committee on Emergency Medical and Trauma Services (1984-1992) and Subcommittee on Disaster Medical Services (1989)

Chairman, Continuing Medical Education Committee, Texas Association of EMS Physicians (1986-1988)

Member, Advisory Commission on State Emergency Communications (1989-1991). Previous National: Member, National Institute for Neurological Disorders and Stroke Panel on Prehospital Care

(1996-1997) National Medical Director, Have-a-Heart, Save-a-Heart Foundation (1993-1999) Member, U.S. Secret Service Emergency Physicians Advisory Panel (1993-1996) Inaugural Board Member and Associate Editor, Academic Emergency Medicine (1993-2000).

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Consultant (Subject Matter Expert), National Standard Curricula, U.S. Department of Transportation National Highway Traffic Safety Administration (1994-1998).

Member, Trauma Systems Evaluation Committee, U.S. Department of Health and Human Services, Health Resources Services Administration (1994-1996).

Member, American Heart Association Emergency Cardiac Care Subcommittee on Advanced Cardiac Life Support (1989-1992) and Panel Member - Guest Speaker, National Standards Conference (1992). Co-author, ACLS Textbook (1994).

Member, Steering Committee Turtle Creek EMS Consensus Conferences (1999-2002) Co-Chair, Media and Public Relations Committee and Member, Steering Committee for the National CPR Weekend Initiative sponsored by the American Heart Association (1999-present) Member, National Basic Cardiac Life Support (BCLS) Subcommittee (1995-2003) and National Media Spokesperson (1999 - present) for American Heart Association (AHA). Member, Steering Committee & College of Fellows, National Academy of Emergency Medical

Dispatch (1992-1994). Chairman, Committee on International Affairs, National Association of EMS Physicians

(1992-1994). Member, Executive Committee, National Association of Emergency Medical Services Physicians (1985-1995); Past-President (1988-1990); Member, Strategic Planning Committee (1993-1994); Chairman, Public Relations Committee (1994-1996); Member, Health Care Policy Committee (1993-1996); Chairman/Member, Program Committee for National Meeting (1984-1990); Research-Development Coordinator (1984-86); Member, Journal-Database Committees (1989) Chief Delegate to the American Medical Association Commission on Emergency Medical Services for

the University Association for Emergency Medicine (1985-1988) and Society for Academic Emergency Medicine (1989)

Member, U.S. Federal Drug Administration Commission on Defibrillator Use and Liaison for American College of Emergency Physicians (1989-1990).

Member, National EMS Organizations' Legislative Coalition (1987-1989) Member, Steering Committee EMS Educator's Committee, Society for Academic Emergency Medicine

(1989-1991) Member, American College of Emergency Physicians Task Force on AIDS (1987-1989) Member, American College of Emergency Physicians, Committee on EMS (1987-1990) Member, U.S. Congress Surgical Critical Care Task Force, Rep. Jim Bates (1988) Co-investigator and Local Coordinator for the International Resuscitation Research Center,

Multi-Center Brain Resuscitation Clinical Trials (NIH Grant #NS15295, NINCDS) (1983-1991) Member, ASTM Committee on EMS Medical Control (1985-1991) Member, Society of Critical Care Medicine, Emergency Medicine Section (1986-1991) and Disaster

Medicine Task Force (1990-1995) Member, Society of Teachers of Emergency Medicine, EMS Educator's Committee (1988-1989) Member, Chairman's Committee for the National Foundation for Infectious Diseases National Forum

on AIDS and Hepatitis B (1988) Editorial Board, American Academy of Orthopedic Surgery text: Early Care and Transport of the Sick

and Injured (1994-2000) Previous International: Secretary, World Association for Emergency and Disaster Medicine 5th World Congress on World

Intersociety Relations (1987). Member, International Scientific Advisory Board, World Association for Emergency and Disaster

Medicine (1987-1991); and Faculty, Sixth World Congress on Emergency and Disaster Medicine, Hong Kong (1989) and Seventh World Congress, Montreal (1991).

Honorary Faculty Member, Chinese Association for Emergency Medicine, Beijing (1989) and Program Co-Director, International Congress on Emergency & Disaster Medicine, Beijing, China,

September 1989. Member, U.S. Delegation to U.S.S.R. Academy of Medical Sciences on Emergency and Disaster

Medical Services (1990). Chair, International Affairs Committee for the National Association of EMS Physicians (1992-1994). Chair, Public Relations Committee for National Association of EMS Physicians (1994-1995).

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Section Editor for Trauma and Section Editor for CPR for Current Opinion in Critical Care (2000-2002) Previous Service for Other Academic Institutions:

Instructor, University of Texas Emergency Medicine Residency Program, Houston (1992-1996). Instructor, Paramedic/ EMT Training Courses, Houston Community College (1983-1996) Instructor, University of Texas Health Science Center, Houston Surgical Residents' Trauma Care

Orientation (1986-1989, 1991-1993) Instructor, Hermann Hospital LifeFlight Nurses' In-service Lecture Series (1985-1988, 1991-1995) Instructor, Hermann Hospital Emergency Lecture Series (1985-1988, 1991-1995) Lecturer, University of Texas, Houston, School of Public Health (1994-1996) PREVIOUS EDUCATIONAL RESPONSIBILITIES: MCP-Hahnemann University -Teaching Course Director, ACLS Courses for Allegheny University Hospitals, Allegheny General house staff

officers (1997-2000) Course Director, Fourth Year Clerkship on Emergency Medicine, Allegheny Campus (EMMD 82301) Course Director, Medical Student Elective on Resuscitation and Emergency Medical Research

(EMMD 82501) Associate Director, EMS Fellowship Program at Allegheny Campus, approved by Society for

Academic Emergency Medicine; (1997-2000) Instructor, Emergency Medicine Didactic Series (1996-2000) Director, Emergency Medicine Visiting Professorship and Grand Rounds Series (1996-2000) Co-Course Director, Allegheny University of the Health Sciences National Trauma Tactics

Symposium, Snowmass and Orlando (1997-1998) Course Director, Allegheny University of the Health Sciences EMS: State of the Science Symposium,

Pittsburgh (1998, 1999) Faculty/Co-Course Director, Allegheny University of the Health Sciences Selected Topics in

Emergency Medicine Conference (1997-1999) Instructor, LifeFlight Didactic Series (1997-2000) Instructor, Emergency Nurses Didactic Series (1997-2000) Instructor, Department of Surgery Trauma ATLS Courses (1997-2000) Instructor, Department of Surgery Trauma Conference (1996-2000) Baylor College of Medicine -Teaching Course Director for Baylor College of Medicine Residents' and Cardiology Fellows' ACLS Training

Programs (1983-1995); about 150 certifications and 50 re-certifications per year (1983-1994) Instructor, Baylor College of Medicine, Core Clinical Pharmacology Course (1988-1996) Program Director, Baylor College of Medicine Joint Emergency Medical Services Grand Rounds and

Visiting Professorship (1993-1996); 10 per year (CME accredited). Course Director for Baylor College of Medicine Medical Student Biannual 6-week Elective (60 students

Annually), Fundamentals of Resuscitation/Prehospital Medicine (Medicine 440) (1986-1996) Course Director, Baylor College of Medicine Special Elective Clerkship (Medicine 577), Prehospital

Medical Care and Intervention Research (1983-1996) Instructor, Ben Taub General Hospital Emergency Center Internal Medicine and Surgery Residents

Didactic Sessions (1982-1995) Program Director, Baylor College of Medicine Emergency Medicine Research Conference; 10 per year

(1992-1996). Program Director, Baylor College of Medicine Emergency Medicine Journal Club; 10 per year

(1992-1994). Course Director, Baylor College of Medicine/Brooke Army Medical Center Emergency Medicine

Department Residency EMS Program (1986-1996); Supervisor/Mentor for 20 senior residents/yr Instructor, Baylor College of Medicine/University of Texas Departments of Surgery, Advanced Trauma

Life Support (ATLS) Courses (1986-1995); generally involves all BCM and UT surgical residents and all UT Emergency Medicine residents.

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Lecturer, Baylor College of Medicine 1st Year Medical Student Noontime Lecture Series (1988-1994). Seattle / University of Washington - Teaching Medic-I Paramedic Training (Training, Certification Evaluations) and Medic-I Physician, Seattle Fire

Department, Seattle, WA (1977-1982) Attending Physician, Emergency Center and Chest Clinic, Harborview Medical Center, University of

Washington, Seattle, WA (1981, 1982) Attending Physician, Respiratory Care (Intensive Care Units) and Pulmonary Medicine at Harborview

Medical Center, University of Washington, Seattle, WA (1981, 1982). Supervisor/Leader, University of Washington Respiratory Disease Division Journal Club (1980-1982) Lecturer, University of Washington Critical Care Conference Series (1981,1982) Conference Instructor, Human Biology (Pulmonary Physiology), University of Washington Medical

School (1980, 1981) MENTOR/ADVISOR RESPONSIBILITIES (Direct Supervision/Mentoring for one or more years): Sample of Prior Mentees with Administrative and Educational Achievements

Matthew J. Wall, Jr., MD (1983-1984). Served as direct mentor for Dr. Wall, when as a medical student, he took a medical student special elective on cardiac resuscitation research. Eventually became he became Professor of Surgery and Chief of Surgical Services, Ben Taub General Hospital, Baylor College of Medicine, Houston, TX. Later co-authored and published landmark papers with him in the arena of trauma resuscitation with articles appearing in major journals such as the New England Journal Medicine.

William H. Bickell, MD (1983-1985). Mentored him directly as a Fellow in EMS and Trauma Services.

Later became Chief of Emergency Trauma Services, St. Francis Trauma Center in Tulsa. As senior author and mentor, co-authored and published landmark papers (with him as first author) in the arena of trauma resuscitation with articles appearing in major journals such as the New England Journal Medicine (NEJM), Annals of Emergency Medicine and Journal of Trauma. He was the winner of multiple scholarly awards for research done as advisee including best oral scientific presentation citations.

Robert R. Bass, MD (1985-1987). As direct supervisor when he worked as assistant (Medical

Director) for the City of Houston EMS, he went on to publish several scientific papers based on joint work; later appointed Director, Washington, DC EMS, (1990-1994) and then Director of MIEMSS (Maryland Institute for EMS Systems); Director, Maryland State EMS and Associate Professor, University of Maryland (1994-2013). Elected President, National Association of EMS Physicians (2003-2005), and President, National Association of State EMS Directors (2005) and he has helped to shape national policy in the arena of EMS and trauma system organization.

Marni J. Bonnin, MD (1988-1991). Mentored her as Senior Fellow in EMS and Assistant Professor

assigned to EMS. As senior investigator, co-authored and published several notable papers (with her as first author) including key scientific papers in major journals that changed global practice and standards of care such as distinct, reproducible criteria for termination of resuscitation efforts for cardiac arrest in the Journal of American Medical Association (JAMA) and cardiac arrest survival in elderly in Critical Care Medicine, all based on her work as direct advisee. Later started and developed Emergency Medicine Residency Program at the University of Texas in Houston.

Robert L. Levine, MD (1990-1993). Eventually became Professor and Chief or Emergency Medicine at

the University of Miami, he was a former faculty member at the Cleveland Clinic and at the Harvard Medical School and also served as Chief of Neurological Intensive Care Unit at Memorial Hermann Hospital and the University of Texas Houston School of Medicine and, later, Chief of Emergency Medicine at the University of Miami. As his direct mentor and senior author, co-published (with him as first author) multiple papers including a notable prospective JAMA study

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published regarding circadian variation in sudden cardiac arrest, as well as several other major publications on cardiac arrest during advisee era.

Peter A. Curka, DO (1991-1994). Mentored him directly as Assistant Professor assigned to EMS; as

senior author and advisee, co-authored and published several key papers (with him as first author) such as ground-breaking innovations including computerized Priority Dispatch Systems and important EMS Quality Assurance programs which were cited as state-of-the-art papers He went on to become Medical Director for Kansas City EMS.

Brian S. Zachariah, MD (1992-1995). Was his direct supervisor when he was Assistant Professor

assigned to EMS. As advisee, he developed and executed several EMS systems organizational studies that advanced EMS operations beyond state-of-the-art. Later recognized as an outstanding educator, he served as Program Director for the Texas College of Emergency Physicians and NAEMSP annual meetings. He later served as international faculty member and co-author for the Emergency Cardiac Care Consensus conference (American Heart Association’s International Standards Conference for CPR, ACLS, etc). As advisee, he published some of the first formal QA studies on Priority Dispatch Systems and later on automated defibrillation use by a large cohort of laypersons. After mentorship period, he went on to serve as Medical Director for the City of Dallas EMS (and surrounding EMS communities) and Associate Professor at the University of Texas Southwestern Medical School, eventually becoming Chief of Emergency Medicine at th University of Texas Medical Branch (UTMB), Galveston, TX and Program Director for the UTMB Emergency Medicine Residency and, later, State of Illinois Chief Medical Coordinator for the Illinois Department of Financial and Professional Regulation, the agency that licenses and regulates physicians in Illinois, a position analogous to that of Medical Director for the Texas State Board of Medical Examiners.

David E. Persse, MD (1993-1995). As advisee, he was assigned as EMS fellow and then Assistant

Professor for EMS. During this period, he designed and executed several research projects that quickly achieved national notoriety. A recognized national speaker, he served as Keynote Speaker for the 1995 EMS International Conference based on work as advisee. He then served as Director of Paramedic Training for Los Angeles County and Associate Medical Director for Los Angeles and in 1996, he became the system-wide Director of the City of Houston Emergency Medical Services System and is now a Professor of Medicine and Surgery. An acclaimed hero in the aftermath of Hurricane Katrina, he received heralded national media coverage for his leadership. He has since been the local Principal Investigator for clinical trials in resuscitation and coronary artery syndrome management and he has co-authored multiple scientific papers regarding EMS system operations that are widely-cited (such as the impact of tiered response systems on cardiac arrest survival. He was recently appointed Public Health Authority for the City of Houston (in addition to his role as EMS System Director). He recently won a coveted national award for Excellence in EMS from the U.S. Metropolitan EMS Medical Directors Coalition.

Craig B. Key, MD (1995-1996). Fellow in EMS, later assigned as Assistant Medical Director for City of

Houston EMS. As advisee, he developed several scientific papers and training manuals used by paramedics nationwide. Also, had several joint scientific papers together. Later assigned as Associate Medical Director for the City of Houston EMS System and Associate Director of EMS for Baylor College of Medicine and Assistant Professor of Emergency Medicine at the University of Texas and later attained similar position as an EMS Medical Director at Ohio State University with on-going efforts into EMS research.

Linda J. Nordeman, MD (1996-1998). As a supervisee (staff physician at Allegheny University

Hospitals, Allegheny General, Pittsburgh), she rapidly developed into the position of Medical Director for the Allegheny University Hospitals Emergency Trauma Center, and subsequently became Chair for the Department of Emergency Medicine, St. John’s Hospital, Springfield, IL.

Samuel Luber, MD, MPH (2004-2007) As his direct advisor, a 1st place award winning large animal

study was accomplished that demonstrated improved brain tissue oxygenation with less frequent ventilation during hemorrhagic states. After a brief stint as Assistant Residency Director at UT

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Southwestern, he is now the lead Program Director (residency director) in EM at the University of Texas medical school in Houston where he has developed numerous educational innovations

Samples of Recent Mentees in the Academic and Research Realms: Jane G. Wigginton, MD (1999-present) Began first collaboration by assisting her with first scientific

abstract when she was Chief Resident in Emergency Medicine at the University of Texas Southwestern Medical Center (UTSWMC) and Parkland Memorial Hospital (PMH) in Dallas. Paper was accepted as an oral presentation at major national meeting and a whole new focus of investigation was launched (role of sex hormones in resuscitation). Later, as direct advisee, she developed several scientific presentations of global interest. One of these papers (regarding bystander CPR interventions for drowning) achieved international notoriety and she was subsequently appointed a panelist for “Resuscitation” techniques for the 1st International Congress on Drowning held in Amsterdam in 2002. She later served as Resuscitation Task Force member and was a co-author of an international standards paper addressing uniform nomenclature, data collection and reporting methods for drowning. Another was a seminal study on the differences in resuscitation outcomes for women versus men. She went on the become an Assistant Professor for Emergency Medicine at UTSWMC and PMH and Deputy Medical Director for the UTSWMC/PMH BioTel (EMS Medical direction) system, which includes the EMS systems for the City of Dallas and more than a dozen surrounding communities. Later recognized by the American Heart Association Emergency Cardiac Care (ECC) Committee leadership as one of the most prolific scientific reviewers for its 2005 Guidelines for CPR and ECC, she was concurrently awarded a 5-year National Institutes of Health (NIH) K-12 grant as a Clinical Scholar at the University of Texas Southwestern Medical Center. Simultaneously, she won the first prize teaching / educator award at the 2006 Emergency Cardiac Care Update Conference for both her scientific work and presentation skills for her presentations in the arena of sex hormone infusion for critical illness and injury. Mentoring her continued in basic science arenas and, with direct guidance as mentor/project editor, she was the first to receive the university’s high risk-high impact grant for a clinical project from the Dean (nobel laureate, Alfred Gilman) at the University of Texas Southwestern Medical Center in Dallas and she then started a small animal lab to investigate effects of sex hormones in traumatic brain injury and in burn-trauma. As a result, in 2008, she successfully secured several Investigational New Drug (IND) approvals for human studies from the FDA for a group of proposed projects for the National Institutes of Health Resuscitation Outcomes Consortium (ie, the ROC). She successfully completed pilot clinical trials of estrogen in severe Traumatic Brain Injury patients and her projects have become priority proposals for future clinical trials in trauma medicine for the U.S. National Institutes of Health (NIH) Resuscitation Outcomes Consortium (ROC) that was recently funded for another six years (through 2015). Also, she was appointed Supervisor for the Human Subjects Core for the long-established NIH P50 Burn Trauma Grant at UT Southwestern and was recently named the NIH Study PI (for the North American ROC network) for definitive multi-center studies on the use of IV estrogen for traumatic brain injury (TBI) and traumatic shock states. Still serving as her first co-author/mentor on several projects, she now has completed numerous basic scientific studies proving the efficacy of estrogen in mitigating the major local and systemic inflammatory responses to conditions such as major burns including suppression of the detrimental effects on the brain, lung, heart and numerous other critical organs in several experimental models. Many of her subsequent scientific presentations have received “best of the best” recognitions at major scientific meetings and she has been formally cited as a ground-breaking young investigator by the NIH leadership in the arena of resuscitation research. Recently promoted to Associate Professor of Surgery/Emergency Medicine, she is now focused on her new leadership role for the NIH ROC. Currentlly there is on-going data assessment of her recently completed pilot studies of estrogen infusion for head injury and post-traumatic shock patients as potential avenues for multi-center clinical trials. In essence, she now pioneers a whole new field of study whose name she has coined, “resuscitative endocrinology”. Her bench research continues to be routinely honored with “best paper” awards such as her 2013 paper for the the American Heart Association Resuscitation Science Symposium, entitled “Single-Dose, Post-Burn Estrogen Significantly Decreases Apoptosis at 7 days and Pro-Inflammatory Cytokines for 45 Days in the Spleen Following Severe Burns”.

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Raymond L. Fowler, MD (2001-present) Began direct mentorship as his supervisor in 2001 in the

realm of the new subspecialty of EMS. Although he only began his academic career in 2001 as an Assistant Professor at UT Southwestern when we recruited him to head the Dallas area EMS system, he is already a full Professor and, as his Co-PI and senior grant editor, he continues to receive direct guidance now the Principal Investigator of a national American Heart Association ($3.5 million) award developed to study ways to improve STEMI management. Exceeding expectations, that on-going award has already resulted in dramatic improvements in interventional times and a concomitant demonstrated life-saving effect decreasing regional mortality rates by more than 2.5 fold (4.6% to 1.9%). The grant is now being renewed for another $6 million. Likewise, with continued mentorship, he has become a Co-Investigator for the NIH ROC and, under his leadership, he has literally doubled the survival rates for out-of-hospital sudden death in the City of Dallas and quadrupled them in smaller suburbs using feedback loop techniques developed through the NIH funding for EMS systems. On a national level, he now has become the most award-winning physician worldwide in the new ABMS subspecialty of EMS including the 2012 National American College of Emergency Physicians (ACEP) National Award for Excellence in EMS. He has also won the corresponding highest level national award from the National Association of EMS Physicians (NAEMSP), the coveted Stewart award, and the corresponding national award from the Metropolitan EMS Medical Directors Coalition. He is the Editor-in-Chief of the NAEMSP textbook that definitively identified the subspecialty competencies for EMS physicians in a four-volume tome. He is now the Division Chief of EMS for the University of Texas Southwestern Medical Center and is s ubiquitous national educator who has developed or helped to co-develop numerous specialized training courses for EMS physicians and paramedics, either the inaugural program director or founding faculty member for highly-successful educational innovations that have been sustained by professional organizations such as ACEP and NAEMSP. He continues to receive mentorship in RFP and federal grant applications as well as faculty development and recruitment. He now runs one of the largest and most successful EMS Divisions (academic unit) in the nation. In 2012, he was honored by the Journal of Emergency Medical Services as an EMS Innovator of the Year

Lynn P. Roppolo, MD (2002-present) As her direct advisor, she developed, with direct guidance, several scientific presentations of national (and now international) interest. One of these papers regarding detection of agonal respirations by dispatcher at 9-1-1 offices received kudos as one of the 8 top papers to note at the 2004 Annual Scientific Symposium of the American Heart Association (AHA) in the AHA President’s opening address. Acting as senior author/mentor, she published, as first author, an international position paper on CPR instructions provided by dispatchers on behalf of the National Academies of Emergency Dispatch. All of these studies were later featured in the summary synopses of the most recent (2010) International Guidelines on CPR as key advances. With continued direct mentorship, she later became the Principal Investigator of a AHA initiative to study a 30 min CPR-AED-choking training course. This elegant study, later published as a landmark paper in Resuscitation, has led to further improvements in CPR training and the training of tens of thousands of laypersons in Dallas alone. She is now an acclaimed Associate Professor and Associate Residency Director at the University of Texas Southwestern Medical Center where she is the Director of Resident Education and Asst Section Chief in Emergency Medicine’s Section of Education. She also became the lead editor of a recently published handbook of Emergency Medicine and is working on several CPR training research projects in conjunction with the National American Heart Association National Center. Also as a mentee, she published several innovative papers including a very clever technique on the detection of cardiac arrest at 9-1-1 dispatch offices by identifying agonal breaths over the telephone, a technique that was rapidly adopted worldwide and has now been attributed to the saving of tens of thousands of lives She continues to receive direct mentorship in the administrative and academic realms, particularly as it affects faculty development and especially for women in academic EM. She was recently cited as one of the top ten Texas Super Doctors in Emergency Medicine in both 2013 and 2014.

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Jeffery C. Metzger, MD (2005 - present) As advisee, he won multiple community service awards for

his heralded performance during Hurricanes Katrina and Rita and later as an imbedded physician on the Dallas Police Department (DPD) SWAT team. Recruited and trained in our unique UT Southwestern fellowship/clinical scholars program called GEMSS (government emergency medical security services) with on-going mentorship, he subsequently was appointed deputy EMS medical director for the Southern tier of Dallas County (2005 - 2011) and as later as Medical Director for the DPD (2007-prssent), a first of its kind position nationwide under direct guidance as a supervisor (City of Dallas Director of Medical Emergency Services). Early on in his tenure as DPD medical director, he was credited with definitively saving the life of a Dallas SWAT officer (shot through the throat) during a tactical incident, one of many at which Dr. Metzger stands by (ground-breaking report published in Prehospital Emergency Care). He has written a scholarly treatise on the role of the physician in the law enforcement setting and recently we co-authored a prospective study on the medical affects of conductive electronic devices (showing minimal risk). He has also developed similar research on in-custody prisoners brought to the emergency department and, a few years, ago, he was appointed to be the Assistant Emergency Department Medical Director for Surgical Liaison Services for the Parkland Health and Hospital System. In 2013, he was appointed main Emergency Department Clinical Medical Director and Liaison for Internal Medicine, Neurology, Psychiatry and other non-surgical services and Supervising Medical Director for the Urgent Care Emergency Department (UCED). In 2016, he was appointed Chief of Service for Emergency Medicine at Parkland Hospital.

Todd Berger, MD (2011 - 2014) As a direct academic supervisee, Dr Todd Berger was recruited and selected as the Program Director (residency director) for the UT Southwestern EM Residency in Austin, TX. Previously the Assistant Program Director at Emory University and the University Medical Center at Brackenridge (UMCB), he developed the Program Information Form (PIF) for the residency. With direction and on-going mentorship, he managed the site visit, received approval and completed a successful match in less than a year. Already filling the first class with more than 1000 applicants in 2012 for the second class of 8 slots. In addition, he also applied for and successfully secured a half-million dollar grant from the State of Texas that will fund his residency program over the next several years.

Kelly R. Klein, MD (2005 – present). As a direct supervisee and mentee, Dr. Kelly Klein was assigned to be deployed into far-forward conditions immediately after the landfall of Hurricane Katrina in late August – early September 2005. Her experience documented in media reports scientific journals and numerous national presentations helped to change our modern concepts of triage in mass disaster situtations. She has since served in Assistant Residency Director and EMS medical director positions. She was appointed to be the Assistant Emergency Department Medical Director for Surgical Liaison Services for the Parkland Health and Hospital System in 2013 and later became one of the founding members of the UT Southwestern Division of Emergency Disaster and Global Health Division (EDGH) in the newly founded Department of Emergency Medicine and she applied for and was accepted into the inaugural class of the UT Southwestern LEAD program (leadership development training) and successfully developed a related initiative as part of that program.

John P. Pease, MD (2009-2016) Appointed to be the Medical Director of the the newly formed 2-SS Observation Unit at Parkland Hospital, Dr. Pease refined protocols that received nationwide attention. Originally intended to manage 3,000 to 4,000 patients and keep 80% from being admitted as an in-patient, the expanding unit now receives nearly 10,000 patients a year and now keeps 90% from being admitted. The success of this unit was largely due to his leadership skills and the attendant protocols that he maintained for the unit. While the productivity of the 2SS unit clearly exceeded expectations here in Dallas, John’s generosity and support for other developing services nationwide led to his recent election as National Chair of the American College of Emerency Physicians (ACEP) Observation Medicine Committee. In 2013, he was unanimously chosen to become the Emergency Medicine (EM) Chief of Service at Parkland and has received unequivocal positive feedback from Parkland and UT Southwestern stakeholders across the board. In 2015, he was selected as a finalist (first runner-up) for the Emergency Department Director of the Year award from the national Emergency Medicine Foundation for which he was

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honored in a special ceremony at the annual scientific Assembly of the ACEP. He retired from UTSW-Parkland in 2016.

CLINICAL ACTIVITIES: Current:

• Attending Staff, Children’s University Hospital System, Dallas, Texas (2000 to present)

• Supervising On-Scene Physician for EMS Systems of Dallas area communities, including City of Dallas (2000-present) and County of Dallas (2014 – present)

• Supervising On-Scene Physician for EMS Systems of South Florida, including Palm Beach County and Broward Sheriff’s Office (Broward County) as well as the Cities of West Palm Beach, Coral Springs, Davie and Port Everglades and Fort Lauderdale International Airport (2015-present).

Previous:

• Attending Staff, Parkland Health and Hospital System, Dallas, Texas (2000-2016)

• Assistant Attending, University Hospital, Southwestern Medical Ctr., Dallas, TX (2000-2015)

• Attending Staff, Seton Hospital and Brackenridge Hospital, Austin, Texas (2013-2015)

• Attending Physician, Allegheny General Hospital, Pittsburgh (1996-2000).

• Attending Physician, Emergency-Trauma Center, Ben Taub General Hospital, Harris County Hospital District, Houston (1982-1996)

• Attending Physician, Emergency, Cardiology and Pulmonary Medicine Staffs, The Methodist Hospital, (1983-1996)

• Consulting Staff Physician, Critical Care Units (Cardiology and Pulmonary Medicine Staff) and Emergency Department, St. Luke's Hospital (1986-1996)

• Consulting Staff Physician, Critical Care Units and Emergency Department, Texas Children's Hospital (1986-1996).

• Consulting Staff Physician, Critical Care Units, Ben Taub General Hospital (1982-1996)

• Consulting Staff Physician, Internal Medicine Staff, St. Joseph's Hospital (1987-1996)

• Attending Staff and Chest Clinic Attending, University of Washington Emergency Trauma Center, Harborview Medical Center (1980-1982)

SUPPORT/GRANTS: -Principal Investigator, Independence of Oxygen Transport and Delivery National Research, National

Research Service Grant Award by National Heart, Lung and Blood Institute (N.I.H. Grant # HL 06386), 1981-1982; $30,000

-Principal Investigator, Predictors of ARDS Washington Lung Association Individual Research Grant,

1982-1983; $16,000/year -Co-investigator, Department of Defense (US Army) Research Grant (RFP #85-R-0016), 1985-1986

(MAST studies); $150,000 -Co-investigator, Brain Resuscitation Clinical Trials II and III (NIH Grant #NS15295, NINCDS)

(1984-1994); $0.5 million/year ($5.5 million total) -Co-investigator, Department of Defense Research Grant (1986-1989) U.S. Army Contract#

DAND17-86-C-6096 Hypertonic Saline and Dextran Studies); $38,000 (pilot; November 1987 - July 1987) and $300,000 (main study; Oct. 1987 - Oct.1989)

-Co-investigator, ISS and AIS in Trauma Patients; Centers for Injury and Disease Control Grant;

January1987 - February 1988; $200,000 -Co-investigator, Preoperative Fluid Infusion Study in Hypotensive Victims of Penetrating Injury;

Warren Foundation, January 1990 -January 1993; $200,000 grant

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-Co-investigator, Multi-center Study of Graded Dose Epinephrine; Abbott Laboratories Grant

(1989-1990) $30,000 Grant -Co-investigator, Stroke and Thrombolysis (STAT) Multi-center Clinical Trials, Awarded by NIH,

1990-1995 (NIH Grant # NIH-NINCDS-89-03; $317,094 per year; total $1.586 million) -Co-investigator, Multi-Center Outcome Research in Cardiac Arrest. Approved but not funded by the

NIH 1991-1996 (NIH application # 1 RO1 HS06695-01; $5,875,405 over 5 years). -Co-investigator, Prehospital Thrombolysis Study, Funded by Genentech, Inc; $125,000 Grant (1992). -Co-investigator, City of Houston/University of Texas Prehospital Diagnostic Electrocardiogram Project

1993-1994 (Awarded by Hermann Hospital, Houston, TX; $330,000 grant). -Principal Investigator, Analysis and Research of Myocardial Ischemia Syndromes (ARAMIS) Project,

City of Houston EMS System; 1993-1995 (Grant Awarded by the Methodist Hospital, Houston, TX; $25,000/yr.).

-Project Director, City of Houston/American Heart Association Mass Infant CPR Training Project;

1993 (Grant Awarded by St. Luke’s and Methodist Hospitals, Houston, TX; $41,000). -Program Director, City of Houston/Baylor College of Medicine EMS Fellowship; 1993-1994 (Grant

Awarded by the Society of Academic Emergency Medicine and sponsored by the Physio-Control Corporation; $50,000).

-Program Director, City of Houston Executive Early Defibrillation Project; 1993 (Grant Awarded by the

Laerdal Corp; $20,000). -Co-investigator, Community Intervention to Reduce Myocardial Infarction Delay Time; 1994-1995

(Awarded by National Heart, Lung and Blood Institute Grant # 1 401HL53135-01); $509,488). -Principal Investigator, City of Houston Center for Resuscitation Cardiac Arrest Registry & Analysis;

1990-1995 (City of Houston funding for multiple research nurses, physician investigators and research assistants – approximately $3.3 Million -- $550,000 per year -- over six years).

-Principal Investigator (Houston site), Assessing the Technology of CPR Strategies: A randomized

trial; 1994-1997; (Awarded by National Institutes of Health;(grant #5R01 HS08197-03); $85,354). -Co-Principal Investigator, HBOC-201 Clinical Trials in Trauma; 2002-2005; awarded by U.S.

Department of Defense to the Biopure Corporation (Approx $4,000,000) – never conducted due to FDA constraints

-Senior Investigator for U.S. Department of Health and Human Services HRSA Grant Proposal for

Developing and Promulgating statewide Disaster Preparedness Training; Amount $4.4 Million over two years, $2.2 Million per year with $1.8 million from HRSA and $400,000 from Texas Department of Health; awarded by HRSA September 2003, and entitled “Texas Bioterrorism Continuing Education Program”. This proposal received the highest rating among all of the two-dozen national awardees and 50 plus total applicants.

-Project Director - City of Dallas Public Access Defibrillation Project; $48,000 funded though Medtronic PhysioControl, Inc. -Co-Investigator and Chair of funded program -Circulatory Compromise: Opportunities to Improve

Outcome. National Institutes of Health and Department of Defense- RFA HL04-001, 1 U01 HL 77887-01. $2,443,349. 00 September 1, 2004-August 31, 2009 (NIH RESUSCITATION OUTCOMES CONSORTIUM). Grant is extended and invited by NIH for renewal (see below).

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-Co-Investigator and Medical Director for site, National Institutes of Health (NIH), National Heart, Lung, Blood Institute multi-center clinical trial; “The IMMEDIATE Trial” (a.k.a., Early EMS and ED Use of GIK for Acute Coronary Syndromes); 2005-08; approx $4.5 Million over 4 years (now terminated). -Co-Investigator, National Institutes of Health (NIH), National Institute for Neurological Disorders and Stroke (NINDS); “Pediatric Traumatic Brain Injury Consortium: Hypothermia”; 2005-10. NIH# 1U01NS052478-01A2 (Pam Okada, Local Principal Investigator; P. David Adelson,

University of Pittsburgh, National PI); approx. $11.5 Million over 5 years). Now terminated. -Co-Investigator, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development and Emergency Medical Services for Children, Maternal Child Health Bureau, Health Resources and Services Administration. “Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department with Seizures” 2008-12. NIH# N01HD043393 (Pam Okada, Local Principal Investigator); approx. $320,000 (over 4 years) locally. Now completed.

-Co-Investigator, Non Interventional F2 - Isoprostane Study - Traumatic Brain Injury (NIFTI - TBI)

and Resuscitative Endocrinology: Single–dose Clinical Uses for Estrogen in Rats

with Traumatic Brain Injury (RESCUE Rats - TBI) Total Award: $84,000; 05/2008 - 12/2009

-Co-Investigator, Hypertonic Saline for Traumatic Resuscitation; National Institutes of Health and the

DoD. HL 077887 (Supplement); Total Award: $370,575: 03/1/2006 – 02/28/2010 -Co-Principal Investigator, Epidemiological Registry for Major Traumatic Injury and Cardiac Arrest;

National Institutes of Health and the American Heart Association. HL 077887 (Supplement); Total Award: $1,295,000; 03/1/2006 – 02/28/2010 (and extended through 2015).

-Co-Principal Investigator, Resuscitation Outcomes Consortium Regional Clinical Center-DFW Center

for Resuscitation Research. Grant # 5 U01 HL077887-08. Originally approved (10/05-12/09) by the NIH (NIH application.RFA# HL-10-006-01; renewed 03/01/10–12/31/15; $942.000 ($600,000 direct).

-Co-Investigator, Title: American Heart Association Symptom Onset to Arterial Reperfusion Improvement Project Approved funding: Raymond L Fowler, Principal Investigator; $3,500,000; funding period: 2010-2012. -Recent Funding Application: Proposal Title: Community-Wide Clinical Research Network Training

Center grant; Funding proposal; NIH Proposed Start and End dates: 07/01/12-6/30/2015 (3 yrs total); Role: Steering Committee Co-Chair and Co-Investigator, Dallas Site. NIH scored initial proposal (10/1/2010) very high (24) on initial review (but not funded).

-Co-Investigator, Emergency and Trauma Education Program (ETEP); Grant number: THECB #

09373; Sponsor: Texas Higher Education Coordinating Board; $206,000 to fund additional residency slots per the State of Texas legislation that supported this initiative (2012 - 2013).

-Co-Investigator, Dallas Site, NIH ProTECT III Multi-Center Clinical Trial, NIH-funded multi-center trial

of progesterone treatment for severe blunt traumatic brain injury, David Wright, Principal Investigator Sponsor: NIH ­ NINDS #R01 NS062778-01/1U01 NS062778-01A1 funded $27,940,226 total for 4/01/09-4/31/14 (now terminated)

-Co-Investigator: Emergency and Trauma Care Education Partnership Program - Renewal – 1; Active, May 15, 2012 – June 30, 2018; Larissa Velez (PI); amount of funding: $462,000

-Co-Investigator: The EvK Clinical Trial: Etomidate versus Ketamine for Emergency Endotracheal Intubation: A Prospective Randomized Clinical Trial (UTSW IRB STU#022015-023, NCT02643381, www.evktrial.org,

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-Co-Principal Investigator: The Impact of a Supermarket Chain AED Program; Active through December 2018; amount of funding: $44,000 over two years -Co-Principal Investigator: Resuscitation Academy and Cardiac Arrest Data Collection Project for Broward County – funded by State of Florida; amount $19,000 (Oct 2016 - Sept 2017)

EDUCATIONAL MATERIALS: Monographs, Unpublished Training Courses and Manuals: Pepe PE. Hemorrhagic Shock Guidelines. City of Houston EMS, November 1983. Pepe PE, Prentice FD. Cardiac Arrest Guidelines, City of Houston Emergency Medical Services, March 1984 and 1988 (Revised). Pepe PE. Difficulty Breathing Management Guidelines. City of Houston Emergency Medical Services, January 1985. Pepe PE, Graham GF. Chest Pain/Discomfort Management Guidelines. City of Houston Emergency Medical Services, April 1985. Pepe PE. Early Respiratory Support of the Critically Ill and Injured Patient, in the Proceedings of the Life Flight Emergency Care Symposium, 1985, Houston, pp 64-79 Pepe PE. Emergency Medical Services in the City of Houston. In: the Proceedings of the International EMS Systems Symposium, 1985, New York, p. 9. McSwain NE, Mattox KL, Pepe PE. Shock - a training program for EMTs and other primary care providers, 1985, Baylor College of Medicine, Houston, Texas. Pepe PE. Multiple Response Incidents: Mass Casualty Disaster Plan, 1986 Trauma, Treatment & Transport Symposium Proceedings. April 1986 Texas A&M University, College Station, TX. Pepe PE. What's new in the Drug Box? Proceedings of the EMS Today National EMS Conference, 1986, New Orleans, LA. Pepe PE. Current Practice of Trauma Management in the Prehospital Setting: Dimensions of Current Research and Statistics, 1986, in the proceedings of the Ninth Annual Symposium on Emergency Medicine, University of Iowa, Cedar Rapids, Iowa. Pepe PE. Weathering the Insurance Crisis in EMS Proceedings of the EMS Today National EMS Conference, 1986, New Orleans, LA. Pepe PE. Ten Major Rules to Follow in the Multiple Casualty Incidents (MCI). Developed for the Texas State Emergency Management Bureau's MCI Response Plan, 1986, Austin, Texas. Pepe PE. Role of Basic and Advanced Life Support in the Community. Baylor College of Medicine/City of Houston EMS, 1987, Houston, Texas. Pepe PE. Resuscitation Decisions: When to Start, When to Stop. Audio-Digest Emergency Medicine March 1987; 4(6); Sides A and B. Pepe PE for the Harris County Medical Society Committee on EMS. Priority Dispatch Manual,1988, 1st Edition, Houston, Texas.

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Pepe PE, Garnett G. Evolving Concepts on Hypovolemic Resuscitation -Why We're Re-thinking It All. Proceedings of the 1988 Annual Meeting of the National Association of EMS Physicians, Washington, D.C. Pepe PE, Matsumoto C. First-Responder Emergency Medical Training Manual, 1st Edition, 1988-1989, Houston, Texas. Pepe PE, Matsumoto C, Almeida SL. First-Responder Level II Emergency Medical Training Manual 1st edition, 1989-1990, Houston, Texas. Pepe PE. Administration of Emergency Medical Services - a guide for the emergency medicine resident. Publication of the Society for Academic Emergency Medicine, Lansing, MI, 1991. Pepe PE, Ginger VF, Stewart D, Ivy MV. First-Responder Level III Emergency Medical Training Manual, 1st edition, 1990-1991, Houston, TX. Pepe PE. Emergency Medical Services in the City of Houston. Publication of the City of Houston EMS System,1991 (revised 1992 and 1994). Pepe PE. Plan A Assist-Cardiac Arrest Guidelines for First Responders. Houston, 1990 Pepe PE, others. Medical direction, Medical director qualifications and Medical director responsibilities. In: Implementing an Early Defibrillation Program. SpaceLabs Medical, Redmond, WA, 1992, pp. 42-49. Pepe PE, Zachariah BS. City of Houston EMS 1st-Responder Program, 1994 Pepe PE. Ten Golden Rules for Dealing with the Media. Developed for the National Association of EMS Physicians (1994) & American College of Emergency Physicians (1992). Pepe PE, Roman-de Meza MA, Hicks M. Corporate High Rise Defibrillation Program First Responder Training Curriculum Manual, Enron Corporation, Houston, TX (1996). Pepe PE, Key CB, Ginger V, Warnke NJ, Copass MK. Emergency Medicine Residents' Orientation Manual, Houston, TX (1996). Stein T, Pepe PE. EMS Fellowship Training Curriculum, Pittsburgh, PA (1997). Pepe PE. First Responder Course Manual for the National Basketball Association (NBA) Trainers Association (the NBTA), Chicago, IL (1997) Pepe PE. Corporate High Rise Defibrillation Program First Responder Training Curriculum Manual, AHERF Corporation, Pittsburgh, PA (1997). Pepe PE. First Responder Course Manual for the Pittsburgh Steelers Professional Football Team, Pittsburgh, PA (1998) Pepe PE. First Responder Course Manual for the Pittsburgh Police Department Protective Services Division, Pittsburgh, PA (1998) Pepe PE. First Responder Course Manual for the U.S. Secret Service Presidential Protection Division, Pittsburgh, PA (1998) Pepe PE, Anderson E. AB-C-D-E Approach to Scene Management for the First Responders (Course and Electronic Slide Presentation) for Dallas Fire Rescue, Dallas, Texas (2001) Pepe PE. Customer Service in EMS, videotape presentation of training course for Dallas Fire Rescue, Dallas, Texas (2001)

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The Bioterrorism Task Force of the Texas Medical Association. Physician Protocols & Patient Information on Biological Agents. Tex Med. 2002; 98 (1): 1-15 (supplement) Pepe PE. Revised First Responder Course Manual for the National Basketball Association (NBA) Trainers Association (the NBTA), Chicago, IL (2008) Pepe PE. A silver history and a golden future. NAEMSP News, Fall 2009;14(4):4. PUBLICATIONS: I. Most Notable Publications -- ARTICLES WITH OVER 100 CITATIONS IN THE MEDICAL LITERATURE OR OF MAJOR CLINICAL / ACADEMIC NOTORIETY Pepe PE and Marini, JJ. Occult positive end-expiratory pressure in mechanically ventilated patients with airflow obstruction -The AUTO-PEEP Effect. Am Rev Resp Dis, July, 1982; 126:166-170 (original description and quantification of "Auto-PEEP"). Pepe PE, Holtman-Reus D, Hudson, LD, and Carrico CJ. Clinical predictors of the adult respiratory distress syndrome. Am J Surgery, July, 1982; 144:124-130 (original prospective definition of risk factors, including first formal description of "sepsis syndrome"). Pepe PE, Hudson LD, Carrico CJ. Early application of positive end-expiratory pressure in patients at risk for the adult respiratory distress syndrome. N Engl J Med, August 5, 1984; 311:281-286 (one of the earliest clinical trials of interventions for ARDS). Bickell WH, Pepe PE, Bailey ML, et al. Randomized trial of pneumatic anti-shock garments in the prehospital management of penetrating abdominal injury. Ann Emerg Med June 1987;16:653-658 (the original prospective randomized trial that challenged this previous standard of care). Brain Resuscitation Clinical Trial II Study Group (including Pepe PE) A randomized clinical study of calcium-entry blocker (lidoflazine) therapy in the treatment of comatose survivors of cardiac arrest. N Engl J Med May 2, 1991;18:1225-1231 (helped to first define standardized nomenclature and reporting data for cardiac arrest studies modeling subsequent Utstein consensus documents) Cummins RO, Ornato JP, Thies W and Pepe PE (senior author). The American Heart Association Emergency Cardiac Care Committee's Subcommittee on Advanced Cardiac Life Support. Improving survival from sudden cardiac arrest: the "chain of survival" concept. Circulation 1991; 83:1832-1847 (original "chain of survival" paper). Brown CG, Martin DR, Pepe PE, et al. Standard versus high-dose epinephrine in out-of-hospital cardiac arrest -a controlled clinical trial. N Engl J Med October 8, 1992;327:1051-1055 (first multi-center prospective trial of an ACLS intervention). Pepe PE, Melker RJ, Zachariah BS. Adult advanced cardiac life support; Part III, Section 1, Airway and Ventilation. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992;268:2199-2203 (the standard of care for advanced resuscitation techniques based on international consensus)..

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Becker LB, Pepe PE. Ensuring effectiveness of community wide emergency cardiac care; Part IX. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992;268:2289-2295 (the standard of care for developing systems of resuscitation care based on international consensus). Adult advanced cardiac life support (ACLS). Part III, Guidelines for cardiopulmonary resuscitation and emergency cardiac care. Emergency Care Committee, Subcommittee on ACLS, American Heart Association. JAMA October 28, 1992;268:2199-2241. Becker LB, Pepe PE. Ensuring the effectiveness of community-wide emergency cardiac care. Ann Emerg Med February 1993;22, Part II:354-365 (state-of-the-art paper from the American Heart Association and the American College of Emergency Physicians). Pepe PE, Mattox KL, Duke JH, Fisher PB, Prentice FD. The effect of full-time-specialized physician supervision on the success of a large urban emergency medical services system. Crit Care Med September 1993;21:1279-1286 (first paper to document the effectiveness of full-time medical direction of EMS). Bonnin MJ, Pepe PE, Kimball KT, Clark PS. Distinct criteria for termination of resuscitation in the out-of-hospital setting. JAMA September 22, 1993;270:1457-1462 (established criteria for on-scene termination of resuscitation efforts). Curka PA, Pepe PE, Ginger VF, Ivy MV, Sherrard RC, Zachariah BS. Emergency medical services priority dispatch: Ann Emerg Med November 1993;22:1688-1695 (original description and results of a computerized EMS dispatch triage program). Pepe PE, Levine RL, Fromm RE, Curka PA, Clark PS, Zachariah BS. Cardiac arrest presenting with rhythms other than ventricular fibrillation: Contribution of resuscitation efforts toward total survivorship. Crit Care Med December 1993;21:1838-1843 (paper that clearly addressed and justified ACLS techniques other than defibrillation). Wall MJ, Pepe PE, Mattox KL. Successful roadside resuscitative thoracotomy: Case report and literature review. J Trauma January 1994;36:131-134 (first reported success with out-of-hospital emergency thoracotomy). Bickell WH, Wall MJ, Pepe PE, et al. Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injury. N Engl J Med October 27,1994;331:1105-1109 (first clinical trial of fluid resuscitation for presumed active hemorrhage). Pepe PE. Roots and philosophy of emergency medical services. In: The National EMS Medical Directors Course and Practicum Textbook, Kuehl AE and Ryan JL (Eds). Publication of the emsAC Foundation Clearwater, FL, 1992, pp.1-8 (the primary training text used by EMS system medical directors in North America). Pepe PE and others on the Advanced Cardiac Life Support subcommittee of the American Heart Association: Textbook of Advanced Cardiac Life Support, American Heart Association, Dallas, TX; 1994. (Internationally recognized standard text used by providers of advanced resuscitative care for cardiac arrest patients). Pepe PE and other members, Subcommittee on Advanced Cardiac Life Support, American Heart Association Committee on Emergency Cardiac Care. Instructors Manual for Advanced Cardiac Life Support. Cummins RO and Billi JE (eds). American Heart Association, Dallas, TX 1994 (text used by ACLS instructors). Fowler RL, Pepe PE, Lewis RJ. Shock evaluation and management. In: Basic Trauma Life Support. Campbell JE (ed), 3rd Edition, Prentice-Hall 1995, New York, pp. 111-124 (main text used as standard of care by paramedics and EMTs regarding trauma care).

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Pepe PE and others on the Board of Editors. Emergency Care and Transportation of the Sick and Injured. Crosby LA, Lewallen DG, (Eds.) 6th Edition, American Academy of Orthopedic Surgeons, Chicago, IL 1995. (the basic textbook used by most EMTs). Pepe PE and others in the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med December 14, 1995;333:1581-1587 (first U.S. trial demonstrating the ability to reverse ischemic stroke with a therapeutic intervention) Becker LB, Berg RA, Pepe PE, et al. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Circulation September 16, 1997; 96:2102-2112 (the seminal scientific statement for cardiac healthcare professionals questioning the absolute and relative need for mouth-to-mouth ventilation during CPR). Pepe PE and others on the Basic Life Support Subcommittee of the Emergency Cardiac Care Committee of the American Heart Association. Instructor’s Manual: Basic Life Support. American Heart Association, Dallas, Texas 1997 (the national standard of care for CPR procedures) Becker LB, Berg RA, Pepe PE, et al: A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation: A statement for Healthcare Professionals from the Ventilation Working Group of the Basic Life Support and Pediatric Life Support Subcommittees, American Heart Association. Ann Emerg Med November 1997; 30:654-666 (the scientific statement for emergency healthcare professionals questioning the absolute and relative need for mouth-to-mouth ventilation during CPR). Becker LB, Berg RA, Pepe PE, et al: A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Respiratory Care September 1997; 30:654-666 (the scientific statement for healthcare professionals which questioned the absolute and relative need for mouth-to-mouth ventilation during CPR). Becker LB, Berg RA, Pepe PE, et al: A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Resuscitation November 1997; 35:189-201 (the scientific statement for healthcare professionals which questioned the absolute and relative need for mouth-to-mouth ventilation during CPR). Pepe PE. Initial links in the chain of recovery for brain attack in access, prehospital care, notification and transport. In: National Institute of Neurological Disorders and Stroke: Setting New Directions for Stroke Care. Marler JR, Jones PW, Emr M (eds). National Institutes of Health, August, 1997; Bethesda, MD, pp. 17-28 (formal policy statement for the National Stroke Plan from the U.S. Government). Pepe PE. Prehospital emergency medical care panel recommendations. In: National Institute of Neurological Disorders and Stroke: Setting New Directions for Stroke Care. Marler JR, Jones PW, Emr M (eds). National Institutes of Health, August, 1997; Bethesda, MD, pp. 47-150 (U.S. government recommendations for National Stroke Plan regarding the prehospital phase of care). Pepe PE, Zachariah B, Sayre M, et al: Ensuring the Chain of Recovery for Stroke in Your Community. Prehospital Emergency Care April/June 1998; 2/2:89-95. (state-of-the-art Review for the EMS personnel based on the NIH consensus panel findings for the National Stroke Plan). Pepe PE, Zachariah B, Sayre M, et al: Ensuring the Chain of Recovery for Stroke in Your Community. Acad Emerg Med April 1998; 5/4:352-358. (state-of-the-art review for the emergency medicine practitioner based on the NIH consensus panel findings for the National Stroke Plan). Pepe PE and others on the Basic Life Support Subcommittee of the Emergency Cardiac Care Committee of the American Heart Association. Providers’ and Instructors’ Manual: Heartsaver-AED for the Lay Rescuer and First Responder. American Heart Association, Dallas, Texas 1998 (The first national training course for training average persons both basic CPR and use of automated external defibrillators as standard of care for bystanders).

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Sirbaugh PE, Pepe PE, Shook JE, Kimball KT, Goldman MJ, Ward MA, Mann DM. Special Contribution Original Research -- A prospective, population-based study of the demographics, epidemiology, management and outcome of out-of-hospital pediatric cardiopulmonary arrest. Ann Emerg Med February 1999; 33:174-184 (recognized as the first comprehensive, population-based study of out-of-hospital pediatric cardiac arrest). Fowler RL, Pepe PE, Lewis RJ. Shock evaluation and management. In: Basic Trauma Life Support. Campbell JE (ed), 4th Edition, Brady/Prentice-Hall Health, Upper Saddle River, NJ, 2000, pp.95-106 (main text used as standard of care by paramedics regarding trauma care). Pepe PE and others. 2000 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. Circulation (Special Supplement) August 22, 2000; 102:1-384. (The new international consensus guidelines from the American Heart Association on CPR, ACLS, Stroke, ACLS and pediatric life support). Pepe PE, Gay M, Cobb LA, Handley AJ, Zaritsky A, Hallstrom A, Hickey RW, Jacobs I, Berg RA, Bircher NG, Zideman DA, de Vos R, Callanan V. Action sequence for layperson cardiopulmonary resuscitation. Ann Emerg Med. April 2001;37:S17-S25. (proceedings of the scientific panels that established new international guidelines from the American Heart Association). Barnes TA, MacDonald D, Nolan J, Otto C, Pepe P, Sayre MR, Shuster M, Zaritsky A. Airway devices. Ann Emerg Med. April 2001;37:S145-S151. (Proceedings of the scientific panels that established new international guidelines from the American Heart Association). Abramson N, de Vos R, Fallat ME, Finucane T, Kettler D, Pepe P, Steen PA, Strobos NC. Ethics in emergency cardiac care. Ann Emerg Med. April 2001;37:S196-S200. (Proceedings of the scientific panels that established new international guidelines from the American Heart Association). Caffrey SL, Willoughby PJ, Pepe, PE, Becker LB Public use of automated defibrillators. N Engl J Med October 17, 2002, 347 (16):1242-7. (first study of public use of AEDs by random rescuers with no duty to act at the Chicago airports). Pepe PE, Raedler C, Lurie K, Wigginton JG. Emergency ventilatory management in hemorrhagic states: elemental or detrimental? J Trauma 2003;54:1048-1057. (laboratory documentation of the severe detrimental effects of intermittent positive pressure ventilation in hemorrhagic shock states even at relative slow respiratory rates). Pepe PE. Executive Summary -- National Institute of Neurological Disorders and Stroke Symposium: Improving the Chain of Recovery for Acute Stroke in Your Community. Publication of the National Institutes of Health (NIH) National Institute for Neurological Disorders and Stroke (NINDS); September 2003; pp. v – vii. Idris A, Berg R, Bierens J, et al including Pepe PE (corresponding author). ILCOR Advisory Statement. Recommended guidelines for uniform reporting of data from drowning: The “Utstein style”. Resuscitation 59(2003) 45-57. (First international standards for uniform nomenclature and reporting of data for drowning-related incidents) Idris AH, Berg RA, Bierens J, et al. Recommended Guidelines for Uniform Reporting of Data From Drowning: The "Utstein Style". Circulation. Nov. 18, 2003 2003;108(20):2565-2574 (see above). Roppolo LP, Pepe PE, Cimon N, et al. Modified cardiopulmonary resuscitation (CPR) instruction protocols for emergency medical dispatchers; rationale and recommendations. Resuscitation May 2005; 65:203-210. (International Position Paper, National Academies of Emergency Dispatch)

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Pepe P and Bierens J. Consensus and recommendations: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2005 pp. 314-323. Eckstein M , Isaacs SM, Slovis CM , Kaufman B, Loflin JR, O’Connor R, Pepe PE (senior, corresponding author): Writing group for the U.S. Metropolitan Municipalities’ EMS Medical Directors’ Consortium (Eagles Coalition). Featured Article: Facilitating EMS Turnaround Intervals at Hospitals in the Face of Receiving Facility Overcrowding. Prehosp Emerg Care July 2005;9: 267-275. Pepe PE. Defending the rights of all individuals to have access to potential life-saving therapies and resuscitation studies. Acad Emerg Med April 2007; 14:e51-e56. Available at: [www.aemj.org]. Accessed [March 8, 2007]. (Testimony of Dr. Paul Pepe; U.S. Food & Drug Administration public hearing on the conduct of human emergency research) Roppolo LP, Pepe PE, Campbell L, Ohman K, Kulkarni H, Idris A, Bean L, Bettes TN, Idris AH. Prospective, randomized trial of the effectiveness and retention of 30-minute layperson training for cardiopulmonary resuscitation and automated external defibrillators: The American Airlines study Resuscitation August 2007; 67 (2):276-285. (ground-breaking study that validated the efficacy of the half-hour CPR and AED training developed by the American Heart Association through a controlled trial that also included documentation of long term retention). Klein KR, Pepe PE, Burkle FM, Nagle NE, Swienton RE. Evolving need for alternative triage management in public health emergencies. Disaster Med Public Health Preparedness 2008;2 (Special Supplement on Triage):S40-S44 (direct documentation of the actual experiences incurred by the authors during their rescue efforts in the aftermath of Hurricane Katrina that reviews the evacuation problems at the New Orleans International Airport, late August through early September 2005). Pepe PE, Copass MK, Sopko G. Clinical trials in the out-of-hospital setting: Rationale and strategies for successful implementation. Crit Care Med 2009;37:S91-101. (the rationale and roadmap for success in implementing clinical trials in the out-of-hospital setting; helped to form the basic philosophy for initiatives such as the National Institutes of Health Resuscitation Outcomes Consortium; also provided a renewed look at the ethics of resuscitation studies). Institute of Medicine of the National Academies Board of Health Policy Sciences, Committee on Preparedness for a Nuclear Event (including Pepe PE). Assessing medical preparedness to respond to terrorist nuclear event. Benjamin GC, McGeary M, McCutcheon, Eds. National Academies Press, Washington, DC, 2009; pp.1-191. (IOM report developed for the U.S. Department of Homeland Security on large city preparations for a nuclear terrorism threat) Roppolo LP, Westfall AH, Pepe PE, Nobel L, Cowan J, Kay JJ. Idris AH. Dispatcher assessments for agonal breathing improve detection of cardiac arrest. Resuscitation 2009:80:769-772. (mechanism to improved detection of cardiac arrest and thus initiation of basic CPR instructions to bystanders by emergency medical dispatchers adopted by the International Academies of Dispatch and highlighted by the American Heart Association in its 2010 International Guidelines on CPR). Metzger JC, Eastman AL, Benitez FL, and Pepe PE. The life-saving potential of specialized on-scene medical support for urban tactical operations: a case report. Prehospital Emergency Care October 2009; 13(4):528-531. (documentation of the life-saving effect of on-scene tactical medicine support by physician specialists integrated into SWAT) DOI:10.1080/10903120903144940 URL: http://dx.doi.org/10.1080/10903120903144940 Topjian AA, Localio AR, Berg RA, Alessandrini EA, Meaney PA, Pepe PE, Larkin GL, Peberdy MA, Becker LB, Nadkarni VM. Women of child-bearing age have better in-hospital cardiac arrest survival outcomes than equal aged men. Crit Care Med May 2010;38:1254-1260.(study of nearly 100,000 in-hospital cardiac arrests documenting improved outcomes for women of child-bearing age inferring an estrogen/progesterone effect).

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Wigginton JG, Pepe PE, Idris AH. Rationale for routine and immediate administration of intravenous estrogen for all critically ill and injured patients. Crit Care Med 2010;28:S620-S629. (comprehensive background documenting the rationale for the study and use of IV estrogen in resuscitation medicine and introducing the field of resuscitative endocrinology) Miller AH, Bhore R, Peshock R, Pepe PE, Yancy C, Xuan L, Chason R, Huet RG, Trimmer C, Miller MM, Davis R, Kashner TM. Is coronary CT angiography a resource sparing strategy in the risk-stratification and evaluation of acute chest pain? Acad Emerg Med 2011:18 (5):458-467. Results of a randomized controlled trial documenting cost-effectiveness of CTA vs. current procedures. Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux BG, Pepe PE, Kudenchuk PJ, Christenson J, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clemen CM, Craig A, Van Ottingham L, Schmidt TA, Wang HE, Weisfeldt ML, Ornato JP, Sopko G and the Resuscitation Outcomes Consortium (ROC) Investigators. The Resuscitation Outcomes Consortium (ROC) PRIMED impedance threshold device (ITD) cardiac arrest trial: A prospective, multi-center, randomized, double-blind, controlled, clinical investigation. N Engl J Med September 1, 2011:365 (9):798-806. Christian MD, Devereaux AV, Dichter JR, et al: Task Force for Mass Critical Care (including Pepe PE). Introduction and executive summary: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct; 146 (4 Suppl):8S-34S. doi: 10.1378/chest.14-0732 PMID: 25144202 IMPACT FACTOR 7.132 Stocchetti N (Co-Chair), Taccone FS, Citerio G, Pepe PE (Co-Chair), Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AIR, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, Helbok R, Tisherman S, Zanier ER, Valenzuela T, Wendon J, Menon DK and Vincent JL. Neuroprotection in the acutely ill: an update. Crit Care April 2015; 19:186. The work product of an international blue ribbon panel on neuroprotection, developed, convened and co-chaired in 2013 in Brussels, Belgium. doi:10.1186/s13054-015-0887-8 Impact Factor 5.04 Idris AH, Guffey D, Pepe PE, Brown SP, Aufderheide TP, Brooks S. Callaway CW, Christenson J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K Sopko G, Stiell IG, Nichol G and the ROC Investigators. Chest compression rates between 100 and 120 per minute are independently associated with increased adult survival following out-of-hospital cardiac arrest. Crit Care Med April 2015;43:840-848. doi: 10.1097/CCM.0000000000000824 Yannopoulos D, Aufderheide TP, Pepe PE, et al. Quality of CPR: An Important effect modifier in

cardiac arrest clinical outcomes and intervention effectiveness trials. Resuscitation 2015 ;94:106–113. IMPACT FACTOR: 5.414 II. Original /Scientific / and Peer-Reviewed Articles (in chronological order --- includes featured articles noted above):

Pepe PE, Marini JJ. Occult positive end-expiratory pressure in mechanically-ventilated patients with airflow obstruction: the Auto-PEEP effect. Am Rev Resp Dis, July, 1982; 126:166-170. Pepe PE, Holtman-Reus D, Hudson LD, and Carrico CJ. Clinical predictors of the adult respiratory distress syndrome. Am J Surgery, July, 1982; 144:124-130. Pepe PE, Stager MA, Thomas RC, Hudson LD, Carrico CJ. Early Prediction of the adult respiratory distress syndrome by a simple scoring method. Annals Emerg Med, December, 1983; 12:749-755.

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Pepe PE, Hudson LD, Carrico CJ. Early application of positive end-expiratory pressure in patients at risk for the adult respiratory distress syndrome. N Engl J Med, August 5, 1984; 311:281-286. Maunder RJ, Harlan JM, Pepe PE, Paskell S, Carrico CJ, Hudson LD. Measurement of plasma fibronectin in patients developing the adult respiratory distress syndrome. J Lab Clin Med, 1984;104:583-590. Pepe PE, Bickell WH, Wyatt CH, et al. Effect of anti-shock trousers on the trauma score - A prospective study in the urban setting. Ann Emerg Med 1985; 14:218-222. Pepe PE, Jerger J, Miller R, Jerger S. Accelerated hearing loss in urban EMS firefighters. Ann Emerg Med 1985; 14:438-442. Pepe PE, Culver, BH. Independently-measured oxygen consumption during reduction of oxygen delivery by positive end-expiratory pressure. Am Rev Resp Dis, 1985;132:788-792. Pepe PE, Copass MK, Joyce TH. Prehospital endotracheal intubation -rationale for training emergency medical personnel. Ann Emerg Med November 1985;14: 1085-1092. Mattox KL, Bickell WH, Pepe PE, Mangelsdorff AD. Prospective, randomized evaluation of anti-shock MAST in post-traumatic hypotension. J Trauma September 1986;26:779-786. Jerger J, Jerger S, Pepe PE, Miller R. Race difference in susceptibility to noise-induced hearing loss. Am J Ontology November 1986;7:425-429. Pepe PE, Troisi CL, Heiberg D, Hollinger FB. Viral hepatitis risk in urban emergency medical services personnel. Ann Emerg Med April 1986;15:454-457. Hollinger FB, Troisi CL, Pepe PE, Heiberg D. Anti-HBs responses to vaccination with human hepatitis B vaccine made by recombinant DNA technology in yeast. J Inf Dis 1986;153:156-159. Pepe PE, Bass RR. Clinical trials of the pneumatic anti-shock garment in the urban prehospital setting. Ann Emerg Med December 1986;15: 1406-1410. Pepe PE and Stewart RD. The role of the physician in the prehospital setting. Ann Emerg Med December 1986;15:1480-1483. Pepe PE. The clinical entity of adult respiratory distress syndrome: definition, prediction and prognosis. Crit Care Clin 1986;2:377-403. Pepe PE, Stewart RD, Copass MK. State of the Art: Prehospital management of trauma. Ann Emerg Med December 1986;15: 1484-1490. Pepe PE, Copass MK, Joyce TH. Prehospital endotracheal intubation. Can J Prehospital Medicine 1986;1:55-65. Pepe PE, Bickell WH, Mattox KL. The effect of anti-shock garments on prehospital survival. J World Assoc Disast Emerg Med Jan/Feb 1987;3(1):40-45. Pepe PE, Wyatt CH, Bickell WH, et al. The relationship between total prehospital time and outcome in hypotensive patients with penetrating trauma. Ann Emerg Med March 1987;16:293-297. Bickell WH, Pepe PE, Bailey ML, et al. Randomized trial of pneumatic anti-shock garments in the prehospital management of penetrating abdominal injury. Ann Emerg Med June 987;16:653-658.

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American College of Emergency Physicians Task Force on AIDS. AIDS -Statement of Principles and Interim Recommendations for Emergency Department Personnel and Prehospital Care Providers. Ann Emerg Med November 1988;17:1249-1251. Pepe PE, Stewart RD, Copass MK. Ten golden rules for urban multiple casualty incident management. Prehosp Disaster Med 1989;4:131-134. Pepe PE. Acute post-traumatic respiratory physiology and insufficiency. Surg Clin North America February 1989; 69(1):157-73. Pepe PE, Bonnin MJ. Limitations and liabilities. Emergency March 1989; 21:40-43. Maningas PA, Mattox KL, Pepe PE, et al. Hypertonic saline-dextran solutions for the prehospital management of traumatic hypotension. Am J Surgery 1989; 157:528-534. Mattox KL, Pepe PE, Bickell WH, et al. The MAST controversy: Analysis of 911 hypotensive patients prospectively randomized. J Trauma 1989;29:1104-1112. Pepe PE. The past, present and future of emergency medical services. Prehosp Disaster Med July-Sept 1989;4:47-49. Pepe PE, Bonnin MJ, Mattox KL. Regulating the scope of EMS services. Prehosp Disast Med 1990;5:59-63. Cummins RO, Thies W, Paraskos J, et al (including Pepe, PE). Encouraging early defibrillation: the American Heart Association and automatic external defibrillators. Ann Emerg Med 1990;19:1245-1248. Fischer RP, Pepe PE, Reed RL, et al. Academic consequences of a trauma system failure. J Trauma 1990;30:784-791. Pepe PE. Controlled studies in the prehospital setting: a viable, important venue for clinical research. Prehosp Disast Med 1990;5:285-288. Pepe PE, Mattox KL, Fischer RP, Matsumoto CM. Geographical patterns of urban trauma according to mechanism and severity of injury. J Trauma Sept. 1990;30:1125-1132. Abramson NS, Safar P, et al (including Pepe, PE). Deferred consent: use in clinical resuscitation research. Ann Emerg Med July 1990;19:781-784. Cummins RO, Chesemore K, White RD, et al (including Pepe, PE). Defibrillator failures: causes of problems and recommendations for improvement. JAMA Aug 1990;264:1019-1025. Advanced Cardiac Life Support Subcommittee of the American Heart Association. Automated External defibrillators and ACLS: a new initiative from the American Heart Association. Am J Emerg Med Jan 1991;9:91-4 Pepe PE, Kvetan V. Field management and critical care in mass disaster. Crit Care Clinics Apr 1991;7:401-420. Brain Resuscitation Clinical Trial II Study Group (including Pepe, PE). A randomized clinical study of calcium-entry blocker (lidoflazine) therapy in the treatment of comatose survivors of cardiac arrest. N Engl J Med May 2, 1991;18:1225-1231. Sutton-Tyrell KS, Snyder JV, Kelsey S, et al (including Pepe, PE). Risk monitoring in randomized trials involving critically ill patients: experience of the brain resuscitation clinical trial II. Am J Emerg Med March 1991;9:112-117.

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Mattox KL, Maningas PA, Moore EE, Mateer JR, Marx JA, Aprahamian C, Burch JM, Pepe PE. Prehospital hypertonic saline/dextran infusion for post-traumatic hypotension -the U.S.A. multi-center trial. Ann Surgery 1991;213:482-491. The Brain Resuscitation Clinical Trial II Study Group. A randomized clinical trial of calcium entry blocker administration to comatose survivors of cardiac arrest: design, methods and patient characteristics. Contr Clin Trials 1991;12:525-545. Cummins RO, Ornato JP, Thies W and Pepe PE. The American Heart Association Emergency Cardiac Care Committee's Subcommittee on Advanced Cardiac Life Support. Improving survival from sudden cardiac arrest: the "chain of survival" concept. Circulation 1991; 83:1832-1847. Pepe PE. Demonstrating the efficacy of basic and advanced life support: a cooperative effort of key community leaders. Houston Heart Bulletin August 1991;11:1-7. Benson NH, Low RB, Chisholm CD, et al. The Society for Academic Emergency Medicine EMS Committee. Air medical transport literature annotated bibliography. Am J Emerg Med Sept. 1991;9:510-519. Ornato JP, Shipley T, Racht EM, Slovis CM, Wrenn KD, Pepe PE, Almeida SL, Ginger VF, Fotre TV. Multi-center study of end-tidal carbon dioxide detection in the prehospital setting. Ann Emerg Med May 1992;21:518-523. Durham LA, Richardson RJ, Wall MJ, Pepe PE and Mattox KL. Emergency center thoracotomy: Impact of prehospital resuscitation. J Trauma June 1992;32:775-779. Levine RL, Pepe PE, Fromm RE, Curka PA, Clark PS. Prospective evidence of a circadian rhythm for out-of-hospital cardiac arrests. JAMA June 3, 1992;267:2935-2937. Martin RR, Bickell WH, Pepe PE, Burch JM, Mattox KL. Prospective evaluation of preoperative fluid resuscitation in hypotensive patients with penetrating truncal injury: J Trauma, Sept. 1992;33:354-362. Fromm RE, Levine RL, Pepe PE. Circadian rhythm in the requests for helicopter transport: cardiac vs. non-cardiac patients. Ann Emerg Med October 1992;21:1196-1199. Zachariah BS, Bryan D, Pepe PE and Griffin M. Follow-up and outcome of patients who decline or are denied transport by EMS. Prehosp Disast Med 1992;7:359-364. Pepe PE, Melker RJ, Zachariah BS. Adult advanced cardiac life support; Part III, Section 1, Airway and Ventilation. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992;268:2199-2203. Brown CG, Martin DR, Pepe PE, et al. Standard versus high-dose epinephrine in out-of-hospital cardiac arrest -a controlled clinical trial. N Engl J Med October 8, 1992; 327:1051-1055. Hedges J, Pepe PE. Cardiac arrest associated with trauma; Part IV, Section 4. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992; 268:2247-2248. McIntyre KM, Crimmins TJ, Safar P, Lo B, Weir RF, Pepe PE. Ethical considerations in resuscitation; Part VIII. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992;268:2282-2288.

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Becker LB, Pepe PE. Ensuring effectiveness of community wide emergency cardiac care; Part IX. Emergency Cardiac Care Committee and Subcommittees, American Heart Association. Guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA October 28, 1992;268:2289-2295. Adult advanced cardiac life support (ACLS). Part III, Guidelines for cardiopulmonary resuscitation and emergency cardiac care. Emergency Care Committee, Subcommittee on ACLS, American Heart Association. JAMA October 28, 1992;268:2199-2241. McAnena OJ, Moore FA, Moore EE, Mattox KL, Marx JA, Pepe PE. Invalidation of the APACHE II scoring system for patients with acute trauma. J Trauma 1992;33:504-507. Levine RL, Pepe PE, Blackstone W, Danzinger J, Varon J. Occult traumatic avulsion of an ovarian dermoid cyst. Am J Emerg Med 1992;10:344-346. Pepe PE. Out-of-hospital research in the urban environment. Prehosp Dis Med 1993;8 S20-24. Pepe PE, Maio RF. Evolving challenges in prehospital trauma services: Current issues and suggested evaluation tools. Prehosp Disast Med 1993;8 S25-34. Pepe PE, Zachariah BS, Chandra N. Invasive airway techniques in resuscitation. Ann Emerg Med February 1993;22, Part II;393-403. Pepe PE. Out-of-hospital resuscitation research: Rationale and strategies for controlled clinical trials. Ann Emerg Med January 1993;22:17-23. Becker LB, Pepe PE. Ensuring the effectiveness of community-wide emergency cardiac care. Ann Emerg Med February 1993;22, Part II:354-365. Pepe PE, Kvetan V. Field management and critical care in mass disaster. Crit Care Clinics Apr 1991;7:401-420. Hoekstra JW, Banks JR, Martin DR, Cummins RO, Pepe PE, Stueven HA, Jastremski M, Gonzalez E, Brown CG. The effect of first responder automated defibrillation on time to therapeutic interventions during out-of-hospital cardiac arrest. Ann Emerg Med August 1993;22:1247-1253. Bonnin MJ, Pepe PE, Kimball KT, Clark PS. Distinct criteria for termination of resuscitation in the out-of-hospital setting. JAMA Sept 22, 1993;270:1457-1462. Curka PA, Pepe PE, Ginger VF, Ivy MV, Sherrard RC, Zachariah BS. Emergency medical services priority dispatch: Ann Emerg Med November 1993;22:1688-1695. Bonnin MJ, Pepe PE, Clark PS. Survival in the elderly following out-of-hospital cardiac arrest. Crit Care Med November 1993;21:1645-1651. Martin DR, Gavin T, Bianco J, Brown CG, Stueven H, Pepe, PE, Cummins RO, Gonzales E, Jastremski M. Initial countershock in the treatment of asystole. Resuscitation 1993;26:63-68. Pepe PE, Levine RL, Fromm RE, Curka PA, Clark PS, Zachariah BS. Cardiac arrest presenting with rhythms other than ventricular fibrillation: Contribution of resuscitation efforts toward total survivorship. Crit Care Med December 1993;21:1838-1843. Martin DR, Soria DN, Brown CG, Pepe PE, Gonzalez E, Jastremski M, Stueven H, Cummins OR. Agreement between paramedic estimated weights and subsequent hospital measurements in adults with out-of-hospital cardiac arrest. Prehosp Disast Med Jan-Mar 1994;9:54-57.

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Wall MJ, Pepe PE, Mattox KL. Successful roadside resuscitative thoracotomy: Case report and literature review. J Trauma January 1994;36:131-134. Martin DR, Moll J, Brown CG, Pepe PE, Gonzalez E, Jastremski M, Stueven H, Cummins RO. Outcome of insulin-treated diabetics receiving epinephrine during cardiac arrest. Am J Emerg Med March 1994;12:147-150. Pepe PE. Emergency medical services. Acad Emerg Med Mar-Apr 1994;1:131-133. Pepe PE, Abramson NS, Brown CG. ACLS -Does it really work? Ann Emerg Med May 1994; 23:1037-1041. Bickell WH, Wall MJ, Pepe PE, et al. Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injury. N Engl J Med October 27,1994;331:1105 -1109. Rogove HJ, Safar P, Sutton-Tyrrell K, et al. Old age does not negate good cerebral outcome after cardiopulmonary resuscitation: analyses from the brain resuscitation clinical trials. Crit Care Med Jan 1995;23:18-25. Pepe PE. Acidosis in acute hemorrhage: detrimental or elemental? Acad Emerg Med February 1995;2:81-82. Pepe PE. ACLS systems and training programs—do they make a difference? Respiratory Care. April 1995;40(4):427-33; discussion 433-6 Zachariah BS, Pepe PE, Curka PA: How to monitor the effectiveness of an emergency medical dispatch system: the Houston model. Eur J Emerg Med 1995;2:123-127. Curka PA, Pepe PE, Zachariah BS, Gray GD, Matsumoto C. Incidence, source and nature of complaints received in a large urban EMS system. Acad Emerg Med June 1995;2:508-512. Zachariah BS, Pepe PE: The development of emergency medical dispatch in the USA: a historical perspective. Eur J Emerg Med 1995;2:109-112. Ghusn HF, Teasdale TA, Pepe PE, Ginger VF. Older nursing home residents have a cardiac arrest survival rate similar to that of older persons living in the community. J Am Geriatr Soc 1995;43:520-527. Cummins RO, White RD, Pepe PE. Ventricular fibrillation, automatic external defibrillators, and the United States Food and Drug Administration: Confrontation without comprehension. Ann Emerg Med Nov. 1995;26:621-631. Pepe PE and others in the National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med December 14, 1995;333:1581-1587. . Biggers W, Zachariah BS, Pepe PE. Emergency medical vehicle collisions in an urban system. Prehosp Disast Med July-September 1996;11:195-201. Pepe PE. Controversies in resuscitation: to infuse or not to infuse (2).Resuscitation 1996;31:7-10. Shoemaker WC, Peitzman AB, Bellamy R, Pepe PE; et al: Resuscitation from severe hemorrhage. Crit Care Med 1996;24:S12-S23. Ornato J, Paradis N, Pepe P, et al: Future directions for resuscitation research: External cardiopulmonary resuscitation, advanced life support. Resuscitation Sept 1996; 32: 139-158.

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Krohmer JR, Swor RA, Benson NH, et al. Prototype curriculum for a fellowship in EMS. Prehosp Disast Med Jan-Mar 1994;9:73-77. Nordeman LJ, Pepe PE. Alpha and Omega: Studying resuscitation at the beginning and end stages of life. Prehosp Emerg Care April-June 1997; 1:120-122. Cobb LA and Discussants (White RD, Pepe PE, Osur M, Amith G). Data collection and retrieval to document the outcomes of cardiopulmonary resuscitation. New Horiz 1997; 5:164-166. Halle AA and Discussants (Tang W, Schock R, Weisfeldt M, Pepe PE, Paradis NA, Bircher NG, Safar P, Chandra NC, Kern KB). Alternatives to Conventional Chest Compression. New Horiz 1997; 5:112-119. Becker LB, Berg RA, Pepe PE, et al. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Circulation Sept 16, 1997; 96: 2102 - 2112. Pepe, PE. Ensuring the Chain of Recovery for stroke in your community. Stroke Interventionist August 1997; 1:10-12. Becker LB, Berg RA, Pepe PE, et al. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Respir Care Sept 1997; 30:654-666. Becker LB, Berg RA, Pepe PE, et al. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation: A statement for Healthcare Professionals from the Ventilation Working Group of the Basic Life Support and Pediatric Life Support Subcommittees, American Heart Association. Ann Emerg Med November 1997; 30:654-666. Becker LB, Berg RA, Pepe PE, et al. A reappraisal of mouth-to-mouth ventilation during bystander-initiated cardiopulmonary resuscitation. Resuscitation Nov. 1997; 35: 189-201. Brott T. Lu M, Kothari R, et al for the NINDS rt-PA Stroke Study Group. Hypertension and its treatment in the NINDS rt-PA stroke trial. Stroke 1998;29:1504-1509 Orledge JD, Pepe PE. Out-of-hospital spinal immobilization: Is it really necessary? Acad Emerg Med March 1998; 5:203-204. Pepe P, Zachariah B, Sayre M, et al: Ensuring the chain of recovery for stroke in your community. Acad Emerg Med April 1998; 5/4:352-358. Pepe P, Zachariah B, Sayre M, et al: Ensuring the chain of recovery for stroke in your community. Prehospital Emergency Care April/June 1998; 2/2:89-95. Sirbaugh PE, Pepe PE, Shook JE, Kimball KT, Goldman MJ, Ward MA, Mann DM. Special Contribution Original Research -- A prospective, population-based study of the demographics, epidemiology, management and outcome of out-of-hospital pediatric cardiopulmonary arrest. Ann Emerg Med February 1999; 33:174-184. Kwiatkowski TG and the Stroke Recombinant Tissue Plasminogen Activator Stroke Study Group. Effects of tissue plasminogen activator for acute ischemic Stroke at one year. N Engl J Med 1999;340:1781-1787. Stout J, Pepe PE, Mosesso VN. All-advanced life support versus tiered-response ambulance systems. Prehosp Emerg Care 2000; 4;1-6. Jager TE, Weiss HB, Coben JH, Pepe PE. Traumatic brain injuries evaluated in U.S. emergency departments, 1992-1994. Academic Emergency Medicine 2000;7:134-140.

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Pepe PE. Controversies in the prehospital management of major trauma. Emergency Medicine 2000; 12(3):180-189. Marler JR, Tilley BC, Lu M, et al, for the NINDS rt-PA Stroke Study Group. Early stroke treatment associated with better outcome. Neurology 2000; 55:1649-1655. Platz E, Scheatzle MD, Pepe PE, Dearwater S. Attitudes towards CPR training in family members of patients with heart disease. Resuscitation 2000; 47;3: 273 - 280. Pepe PE and other contributors. 2000 Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. Circulation (Special Supplement) August 22, 2000; 102:1-384. (The new international consensus guidelines from the American Heart Association on CPR, ACLS, Stroke, ACLS and pediatric life support). Pepe PE, Swor RA, Ornato JP, et al. Resuscitation in the out-of-hospital setting: medical futility criteria for on-scene pronouncement of death. Prehospital Emergency Care 2001;5:79-87. Barnes TA, MacDonald D, Nolan J, Otto C, Pepe P, Sayre MR, Shuster M, Zaritsky A. Airway devices. Ann Emerg Med. April 2001;37:S145-S151. Pepe PE. Clinical Update: CPR in Schools. Dal Med J 2001;87:pp.290-293. Abramson N, de Vos R, Fallat ME, Finucane T, Kettler D, Pepe P, Steen PA, Strobos NC. Ethics in emergency cardiac care. Ann Emerg Med. April 2001;37:S196-S200. Pepe PE, Anderson E. Multiple Casualty Incident Plans: Ten Golden Rules for Prehospital Management. Dallas Med J. November 2001; 462-468. Pepe PE, Gay M, Cobb LA, Handley AJ, Zaritsky A, Hallstrom A, Hickey RW, Jacobs I, Berg RA, Bircher NG, Zideman DA, de Vos R, Callanan V. Action sequence for layperson cardiopulmonary resuscitation. Ann Emerg Med. 2001;37:S17-S25. Pepe PE, Mosesso VN Jr, Falk JL. Prehospital fluid resuscitation of the patient with major trauma. Prehosp Emerg Care. Jan – Mar 2002;6(1):81-91. Carrico CJ, Holcomb JB, Chaudry, et al. Scientific priorities and strategic planning for resuscitation research and life-saving therapy following traumatic injury: report of the PULSE trauma work group. Shock 2002; 17:185-188 Wigginton JG, Pepe PE, Bedolla JP, DeTamble LA, Atkins JA. Sex-related differences in the presentation and outcome of out-of-hospital cardiopulmonary arrest: A multiyear, prospective population-based study. Crit Care Med. 2002;30(4):S131-136. Pepe PE, Rinnert KJ. Bioterrorism and medical risk management. The International Lawyer 2002; 36 (1) 9-20. Cairns CB, Pepe PE, Becker LB. Resuscitation of cells and systems: The PULSE research initiative. Acad Emerg Med 2002;(9)6:613-614. Pepe PE, Rinnert KJ. Bioterrorism and Risk Management. Dallas Medical Journal September 2002 88:9: 314-317. Caffrey SL, Willoughby PJ, Pepe, PE, Becker LB Public use of automated defibrillators. N Engl J Med October 17, 2002, 347 (16):1242-7. First study of public use of AEDs by random rescuers with no duty to act at the Chicago airports.

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Bar-Joseph, G, Abramson N, Clinical Trial III Study Group. Clinical use of sodium bicarbonate during cardiopulmonary resuscitation-is it used sensibly? Resuscitation 2002;5:47-55. Pepe PE, Raedler C, Lurie K, Wigginton JG. Emergency ventilatory management in hemorrhagic states: elemental or detrimental? J Trauma 2003;54:1048-1057. Sayre MR, Swor R, Pepe PE, Overton J. Current Issues In cardiopulmonary resuscitation. Prehosp Emerg Care 2003;7:24-30. Key CB. Pepe PE. Persse DE. Calderon D. Can first responders be sent to selected 9-1-1 emergency medical services calls without an ambulance? Acad Emerg Med April 2003;10:339-46 Idris A, Berg R, Bierens J, et al including Pepe PE (corresponding author). For the ILCOR Advisory Statement. Recommended guidelines for uniform reporting of data from drowning: The “Utstein style”. Resuscitation 2003;59:45-57. Idris AH, Berg RA, Bierens J, et al. Recommended Guidelines for Uniform Reporting of Data From Drowning: The "Utstein Style". Circulation. November 18, 2003 2003;108(20):2565-2574. Pepe, PE. Managing shock in polytrauma. Brit Med J Nov. 15, 2003;327(7424):1119-1120. Pepe, PE. Automated defibrillators best seen as part of CPR. Brit Med J (USA) 2004; 4:7-8 Pepe PE, Fowler R, Roppolo L, Wigginton J. Re-appraising the concept of immediate defibrillatory attempts for out-of-hospital ventricular fibrillation. Crit Care 2004, 8:41-45. Hall WL, Myers JH, Pepe PE, Larkin GL, Sirbaugh PE, Persse DE. Paramedics perspective about termination of resuscitation efforts in pediatric patients. Resuscitation 2004:60:175-187. Pepe PE, Lurie KG, Wigginton JG, Raedler C, Idris AH. Detrimental hemodynamic effects of assisted ventilation in hemorrhagic states. Crit Care Med Sept 2004 32:(Supplement) 414-420. Kwiatkowski T, Libman R, Tilley BG, et al (writing group for the National Institute of Neurological Disorders and Stroke (NINDS) Recombinant Tissue Plasminogen Activator Stroke Study Group, including Pepe PE). The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study. Annals Emerg Med April 2005, 45:377-384. Roppolo LP, Pepe PE, Cimon N, et al. Modified cardiopulmonary resuscitation (CPR) instruction protocols for emergency medical dispatchers; rationale and recommendations. Resuscitation May 2005; 65:203-210. Wigginton JG, Pepe PE. Basic cardiopulmonary resuscitation. Europ Hosp Aug 2005;14:100-11. Eckstein M, Isaacs SM, Slovis CM , Kaufman B, Loflin JR, O’Connor R, Pepe PE (senior, corresponding author): Writing group for the U.S. Metropolitan Municipalities’ EMS Medical Directors’ Consortium (Eagles Coalition). Featured Article: Facilitating EMS turnaround intervals at hospitals in the face of receiving facility overcrowding Prehosp Emerg Care July 2005;9: 267-275. Miller AH, Pepe PE, Brockman CR, Delaney KA. ED ultrasound in hepatobiliary disease. J Emerg Med

January 2006;30:69-74. Pepe PE, Wigginton JG. Key advances in critical care in the out-of-hospital setting: the evolving role of laypersons and technology. Critical Care 2006;10:119 (electronic publication doi:10.1186/cc4838) Fink MP, Suter PM and others (incl Pepe PE). The future of our specialty: critical care medicine a decade from now. Critical Care Med 2006; 34:1811-1815.

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Nemeth IR, Rinnert KJ, Swienton RE and Pepe PE. Catastrophic care: when hospitals are overwhelmed. European Hospital 2006; 15 (1): 10-11. Pepe PE. Half-hour CPR courses: when less is better. J Emerg Med Svcs May 16, 2006;31:1-2. (on-line at http://www.jems.com/Columnists/eagles/articles/104621/ ). Rinnert KJ, Wigginton JG, Pepe PE. Outdated concepts in management of disasters. China J Emerg Resuscitation Disast Med 2006;1:14-16. Vincent JL, Fink MP, Marini JJ, Pinsky MR, Sibbald W, Singer M, Suter P, Cook D, Evans T, Pepe PE. Intensive care and emergency medicine: progress over the past 25 years. Chest 2006;129:1061-7.

Fowler RL, Gallagher JV, Isaacs SM, Ossman E, Pepe PE, Wayne, M. The role of intraosseous vascular access in the out-of-hospital environment. Prehosp Emerg Care Jan 2007;11:63-66. Pepe PE, Roppolo LP, Idris AH. Traditional or 30-minute CPR-AED training? Europ Hosp 2007;16:8-9. Coule PL, Schwartz RB, Swienton RE, Mitchell G, Dallas C, Pepe PE. Myths of disaster management. Ann Emerg Med Feb 2007; 49:244-245. North CS, Hong BA, Pepe PE. Staff burnout in the intensive care unit during major catastrophes: the disaster “cascade”. ICU Management March 2007;7(1):10-12. Pepe PE. In-hospital care – extension of EMS: Reversing the traditional perspective. J Emerg Med Services October 2007:32(10):S4. Roppolo LP, Pepe PE, Campbell L, Ohman K, Kulkarni H, Idris A, Bean L, Bettes TN, Idris AH. Prospective, randomized trial of the effectiveness and retention of 30-minute layperson training for cardiopulmonary resuscitation and automated external defibrillators: The American Airlines study Resuscitation August 2007; 74 (2):276-285. Pepe PE, Food and Drug Administration public hearing on the conduct of emergency clinical research: testimony of Dr. Pepe--defending the rights of all individuals to have access to potential life-saving therapies and resuscitation studies. Acad Emerg Med. April 2007; 14:e51-e56 [www.aemj.org]. http://www.aemj.org/cgi/search?volume=&firstpage=&author1=Pepe&author2=&titleabstract=&fulltext=&fmonth=Jan&fyear=2007&tmonth=Apr&tyear=2007&hits=10&sendit=Search&journalcode=aemj&fdatedef=1+January+1994&tdatedef=12+April+2007 (Accessed [March 8, 2007]. Pepe PE. In-hospital care – extension of EMS: Reversing the traditional perspective. J Emerg Med Services October 2007:32(10):S4. North CS, King RV, Polatin P, Smith RP, Lagrone A, Tyler D, Larkin GL, Fowler RL, Pepe PE. Psychiatric illness among transported hurricane evacuees: acute phase findings in a large receiving shelter site. Psychiatric Annals February 2008;38(2):104 -113. Myers JB, Slovis CM, Eckstein M, et al. Evidence-based performance measures for emergency medical service systems: a model for EMS benchmarking. A consensus document from the U.S. Metropolitan Municipalities EMS Medical Directors Consortium. Pepe PE (Senior Corresponding Author). Prehosp Emerg Care April 2008:12:141-151.

Pepe PE, Dutton RP, Fowler RL. Preoperative resuscitation of the trauma patient. Curr Opin Anesth April 2008; 21:216-221.

Pepe PE (Discussant) for Kragh JF, Walters TJ, Baer DG, Fox CJ, Wade CE, Salinas J, Holcomb JB. Practical use of emergency tourniquets to stop bleeding in major limb trauma. J Trauma February 2008; 64:Special Supplement:S49-S50.

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Miller AH, Nazeer S, Pepe PE, Estes B, Gorman A, Yancy C. Acutely decompensated heart failure in a county emergency department: a double-blind, randomized, controlled comparison of nesiritide vs. placebo treatment. Ann Emerg Med May 2008;51:580-582. Eastman AL, Metzger JC, Pepe PE, Benitez Fl, Decker J, Rinnert KJ, Friese RS. Conductive electrical weapons: A prospective, population-based study of the medical safety of law enforcement use. J Trauma June 2008;64:1567-1572. Klein KR, Pepe PE, Burkle FM, Nagle NE, Swienton RE. Evolving need for alternative triage management in public health emergencies. Disast Med Public Health Prep 2008; 2 (Suppl 1):S40-S44. Pepe PE, Heightman AJ. What’s hot (and cold) in prehospital medicine: 2009 State of the Science. J Emerg Med Services January 2009 34:4. Pepe PE. The CPR revolution: returning to the basics. J Emerg Med Services Jan. 2009 34:5-9. Pepe PE, Copass MK, Sopko G. Clinical trials in the out-of-hospital setting: Rationale and strategies for successful implementation. Crit Care Med 2009;37:S91-101. Pepe PE (Discussant) for Lehmann R, Oh J, Killius S, Cornell M, Furay E, Martin M. Interhospital patient transport by rotary wing aircraft in a combat environment: risks, adverse events, and process improvement. J Trauma April 2009; 66:S:31-S36. Roppolo LP, Wigginton JG, Pepe PE. Revolving back to the basics in cardiopulmonary resuscitation. Minerva Anesthesiologica May 2009:75:301-305 Roppolo LP, Westfall AH, Pepe PE, Nobel L, Cowan J, Kay JJ. Idris AH. Dispatcher assessments for agonal breathing improve detection of cardiac arrest. Resuscitation August 2009:80:769-772. doi:10.1016/j.resuscitation.2009.04.013 Roppolo LP, Pepe, PE. Retention, retention, retention: targeting the young in CPR skills training! Crit Care 2009;13185-186.

Thakar HJ, Pepe PE, Rohrich RJ. The role of the plastic surgeon in disaster relief. Plastic and Reconstructive Surgery September 2009;124:975-981. Metzger JC, Eastman AL, Benitez FL, and Pepe PE. The life-saving potential of specialized on-scene medical support for urban tactical operations. Prehospital Emergency Care October 2009; 13(4):528-531. DOI:10.1080/10903120903144940 URL: http://dx.doi.org/10.1080/10903120903144940 Ghosh R, Pepe PE. The Critical Care Cascade - a systems approach. Curr Opin Crit Care 2009 15(4):279-283. doi: 10.1097/MCC.0b013e32832faef2 Mechem CC, Goodloe JM, Richmond NJ, Kaufman BJ, Pepe PE (Writing group for the U.S. Metropolitan Municipalities EMS Medical Directors Consortium). Resuscitation center designation: recommendations for emergency medical services practices. Prehosp Emerg Care 2010; 14(1):51-61. Pepe PE, Heightman AJ. Driving clinical innovation through EMS. J Emerg Med Services; October 2009;34(10):3. Wigginton JG. Pepe PE, Idris AH. Sex, drugs and R&R (reanimation and resuscitation): the rapidly evolving field of resuscitative endocrinology. J Emerg Med Services January 2010;35 (Special Supplement; EMS State of the Science):21-23.

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Heightman AJ. Pepe PE. ARCTIC program and other initiatives bring more science into the field. J Emerg Med Services January 2010;35 (Special Supplement; EMS State of the Science):4-5. Topjian AA, Localio AR, Berg RA, Alessandrini EA, Meaney PA, Pepe PE, Larkin GL, Peberdy MA, Becker LB, Nadkarni VM. Women of child-bearing age have better in-hospital cardiac arrest survival outcomes than equal aged men Crit Care Med May 2010;38:1254-1260. Wigginton JG, Pepe PE, Idris AH. Rationale for routine and immediate administration of intravenous estrogen for all critically ill and injured patients. Crit Care Med 2010;28:S620-S629. King RV, North CS, Larkin GL, Downs DL, Klein KR, Fowler RL, Swienton RE, Pepe PE. Attributes of effective disaster responders: focus group discussions with key emergency response leaders. Disast Med Public Health Prep December 2010:4:332-338. Brywczynski J, McKinney J, Pepe P, Eckstein M, Myers JB, Fowler RL, Slovis C; Writing Group for the U.S. Metropolitan EMS Medical Directors Consortium. EMS transport decisions in post-traumatic circulatory arrest: Are national practices congruent? J Trauma 2010;69;1154-1160. Miller AH, Pepe PE, Bhore R, Peshock R, Yancy CC, Xuan L, Miller MM, Huet GR, Trimmer C, Davis R, Kashner TM. Is coronary CT angiography a resource sparing strategy in the risk-stratification and evaluation of acute chest pain? Results of a randomized controlled trial. Acad Emerg Med May 2011:18 (5):458-467. Roppolo LP, Heyman R, Pepe PE, Wagner J, Commons B, Miller R, Allen E, Horne L, Wainscott MP, Idris AH. A randomized controlled trial comparing traditional training in cardiopulmonary resuscitation (CPR) to self-directed CPR learning in first year medical students: the two-person CPR study. Resuscitation 2011; 82:319-325, originally published on-line October 16. 2010; doi: 10.1016/J.Resuscitation.2010.10.025 Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux BG, Pepe PE, Kudenchuk PJ, Christenson J, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clemen CM, Craig A, Van Ottingham L, Schmidt TA, Wang HE, Weisfeldt ML, Ornato JP, Sopko G and the Resuscitation Outcomes Consortium (ROC) Investigators. The Resuscitation Outcomes Consortium (ROC) PRIMED impedance threshold device (ITD) cardiac arrest trial: A prospective, multi-center, randomized, double-blind, controlled, clinical investigation. N Engl J Med September 1, 2011;365 (9):798-806. Roppolo LP, Wigginton JG, Pepe PE. Advances in resuscitative trauma care. Minerva Anestesiologica October 2011;77:993-1002.

Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, Pepe PE, Rea TD, Schmicker RH, Vaillancourt C, Chugh SS; Resuscitation Outcomes Consortium. Socioeconomic status and incidence of sudden cardiac arrest. Can Med Assoc J October 18 2011;183(15):1705-1712. DOI:10.1503/cmaj.101512

Metzger JC, Eastman AL, Pepe PE. Critical Care - cardiac arrest and cardiopulmonary resuscitation. Critical Care December 2011;16:239-246.

Roppolo LP, White PF, Hatten B, Hynan LS, Pepe PE. Use of the trachview videoscope as an adjunct to direct laryngoscopy for teaching orotracheal intubation. Europ J Emerg Med 2012 19(6):196-199. Pepe PE, Schneider SM. Primum non nocere: Protecting our patients through research and a better understanding of what we do. J Emerg Services August 2012:37:34-40. Goldberg SA, Metzger JC, Pepe PE. Critical care – out-of-hospital cardiac arrest and trauma. Critical Care December 2012;16:247 (http://ccforum.com/content/16/6/247)

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Pepe PE, Heightman AJ. Advances in cardiac resuscitation call for new EMS field practices. J Emerg Med Services September 2012;37(suppl):3. Goldberg SA, Leatham A, Pepe PE. Critical care – out-of-hospital cardiac arrest and trauma. Critical Care December 2013;17:248 http://ccforum.com/content/17/6/248 Chamberlain JM, Okada P, Holsti M, et al for the Pediatric Emergency Care Applied Research Network Investigators (including Pepe PE). Lorezepam vs diazepam for pediatric status epilepticus: a randomized clinical trial. JAMA 2014;311:1652-1660.doi:10.1001/jama.2014.2625. Goldberg SA, Kharbanda B, Pepe PE. Year in review 2013: critical care - out-of-hospital cardiac arrest, traumatic injury and other emergency care conditions. Crit Care 2014:18:593 (on-line 29 October 2014) doi:10.1186/s13054-014-0593-y Impact Factor 5.04 Stocchetti N (Co-Chair), Taccone FS, Citerio G, Pepe PE (Co-Chair), Le Roux PD, Oddo M, Polderman KH, Stevens RD, Barsan W, Maas AIR, Meyfroidt G, Bell MJ, Silbergleit R, Vespa PM, Faden AI, Helbok R, Tisherman S, Zanier ER, Valenzuela T, Wendon J, Menon DK and Vincent JL. Neuroprotection in acute brain injury: an up-to-date review. Crit Care April 2015;19:186 doi:10.1186/s13054-015-0887-8 Impact Factor 5.04 Pepe PE, Roppolo LP, Fowler RL. Prehospital endotracheal intubation: elemental or detrimental? Crit Care 2015;19:121 doi:10.1186/s13054-015-0808-x

Impact Factor 5.04 Idris AH, Guffey D, Pepe PE, Brown, SP, Brooks SC, Callaway CW, Christenson J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K, Sopko G, Stiell I, Nichol G, Aufderheide TP for The Resuscitation Outcomes Consortium Investigators. Chest compression rates and survival following out-of-hospital cardiac arrest. Crit Care Med April 2015;43:840-848. doi: 10.1097/CCM.0000000000000824 Impact Factor: 6.15 Pierce AE, Roppolo LP, Owens P, Pepe PE, Idris AH. The need to resume chest compressions immediately after defibrillation attempts: an analysis of post-shock rhythms and duration of pulselessness following out-of-hospital cardiac arrest. Resuscitation April 2015;89:162-168. Pepe PE. Partnering medicine and public service. ICU Management, 2015;15(2):84-6. Yannopoulos D, Aufderheide TP, Pepe PE, et al. Quality of CPR: An Important effect modifier in

cardiac arrest clinical outcomes and intervention effectiveness trials. Resuscitation 2015 ;94:106–113. IMPACT FACTOR: 5.414 Debaty G, Lurie K, Metzger A, Lick M, Bartos JA, Rees JN, McKnite S, Puertas L, Pepe P, Fowler R. Reperfusion injury protection during Basic Life Support improves circulation and survival outcomes in a porcine model of prolonged cardiac arrest. Resuscitation 2016; 105:29-35. IMPACT FACTOR: 5.414

Pepe PE. That conclusion was accurate – but not true. J Emerg Med Services 2017; 52:59-64

Pepe PE. Resuscitating resuscitation. Current Opin Crit Care 2017:23: 181-182 doi: 10.1097/MCC.0000000000000411. PMID: 28398909 Impact Factor 2.706

Pepe PE, Aufderheide TP. EBM vs. EBM: combining evidence-based and experienced based medicine in resuscitation medicien. Current Opin Crit Care 2017; 23:199-203 doi: 10.1097/MCC.0000000000000413 PMID: 2839891 Impact Factor 2.706

Younguist ST, Scheppke, KA, Pepe PE. Supportive technology in the resuscitation of out-of-hospital cardiac arrest patients Current Opin Crit Care June 2017:23: 209-214.

doi: 10.1097/MCC.0000000000000409. PMID: 28383297 Impact Factor 2.706

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McCormick TN, McVaney KE, Pepe PE. No small matter: pediatric resuscitation. Current Opin Crit Care 2017:23:193-198. doi: 10.1097/MCC.0000000000000410. PMID: 28402986 Impact Factor 2.706 Wigginton JG, Pepe PE, Simpkins JW, Gaston JW, Wigginton KG, AbdelFattah KR, Minei JP, Maass DL. Early, single-dose, post-burn estrogen significantly decreases burned skin and systemic inflammatory response for 7 days following severe burn injury. J Trauma 2015 (final revisions). Matchett G, Ryan TJ, Sunna MC, Lee SC, and the EvK Trial Group (including Pepe PE). Measuring

the impact of community consultation and public disclosure for emergency clinical research: is the

community aware? Status: Manuscript submitted to Clinical Trials and currently under peer-review.

III. Peer-Reviewed Consensus Publications of the American College of Chest Physicians (ACCP) Task Force on Mass Critical Care – Panelist & Task Force Member Tosh PK, Feldman H, Christian MD, Devereaux AV, et al --Task Force for Mass Critical Care including Pepe PE). Business and continuity of operations: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): e103S-17S. doi: 10.1378/chest.14-0739 PMID: 25144857 IMPACT FACTOR 7.132 Dichter JR, Kanter RK, Dries D, et al; Task Force for Mass Critical Care; Task Force for Mass Critical Care (including Pepe PE). System-level planning, coordination, and communication: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct; 146 (4 Suppl): e87S-e102S. doi: 10.1378/chest.14-0738 PMID: 25144713 IMPACT FACTOR 7.132 Dries D, Reed MJ, Kissoon N, et al: Task Force for Mass Critical Care (including Pepe PE). Special populations: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest. 2014 Oct; 146 (4 Suppl): e75S-86S. doi: 10.1378/chest.14-0737 PMID: 25144661 IMPACT FACTOR 7.132 Christian MD, Sprung CL, King MA, et al; Task Force for Mass Critical Care (including Pepe PE); Task Force for Mass Critical Care. Triage: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest. 2014 Oct; 146 (4 Suppl): e61S-74S. doi: 10.1378/chest.14-0736 PMID: 25144591 IMPACT FACTOR 7.132 King MA, Niven AS, Beninati W, et al; Task Force for Mass Critical Care (including Pepe PE). Evacuation of the ICU: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct; 146 (4 Suppl): e44S-60S. doi: 10.1378/chest.14-0735 PMID: 25144509 IMPACT FACTOR 7.132 Geiling J, Burkle FM Jr, West TE, et al: Task Force for Mass Critical Care (including Pepe PE). Resource-poor settings: response, recovery, and research: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest. 2014 Oct 146 (4 Suppl):e168S-77S. doi: 10.1378/chest.14-0745 PMID: 25144410 IMPACT FACTOR 7.132 Einav S, Hick JL, Hanfling D, Erstad BL, et al: Task Force for Mass Critical Care (including Pepe PE). Surge capacity logistics: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct;146 (4 Suppl):e17S-43S. doi: 10.1378/chest.14-0734. PMID: 25144407 IMPACT FACTOR 7.132 Geiling J, Burkle FM Jr, Amundson D, et al: Task Force for Mass Critical Care (including Pepe PE). Resource-poor settings: infrastructure and capacity building: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): e156S-67S. doi: 10.1378/chest.14-0744 PMID: 25144337 IMPACT FACTOR 7.132

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Hick JL, Einav S, Hanfling D, Kissoon N, Dichter JR, Devereaux AV, Christian MD; Task Force for Mass Critical Care (including Pepe PE). Surge capacity principles: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct; 146(4 Suppl): e1S-e16S. doi: 10.1378/chest.14-0733. PMID: 25144334 IMPACT FACTOR 7.132 Biddison LD, Berkowitz KA, Courtney B, et al: Task Force for Mass Critical Care (including Pepe PE). Ethical considerations: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): e145S-55S. doi: 10.1378/chest.14-0742. PMID: 25144262 IMPACT FACTOR 7.132 Ornelas J, Dichter JR, Devereaux AV, et al: Task Force for Mass Critical Care (including Pepe PE). Methodology: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): 35S-41S. doi: 10.1378/chest.14-0746 PMID: 25144246 IMPACT FACTOR 7.132 Courtney B, Hodge JG Jr, Toner ES, et al: Task Force for Mass Critical Care (including Pepe PE); Legal preparedness: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): e134S-44S. doi: 10.1378/chest.14-0741 PMID: 25144203 IMPACT FACTOR 7.132 Christian MD, Devereaux AV, Dichter JR, et al: Task Force for Mass Critical Care (including Pepe PE). Introduction and executive summary: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement. Chest 2014 Oct; 146 (4 Suppl):8S-34S. doi: 10.1378/chest.14-0732 PMID: 25144202 IMPACT FACTOR 7.132 Devereaux AV, Tosh PK, Hick JL, et al: Task Force for Mass Critical Care (including Pepe PE). Engagement and education: care of the critically ill and injured during pandemics and disasters: Chest consensus statement. Chest 2014 Oct; 146 (4 Suppl): e118S-33S. doi: 10.1378/chest.14-0740 PMID: 25144161 IMPACT FACTOR 7.132 IV. Full-length Papers from the National Institutes of Health (NIH) Resuscitation Outcomes Consortium (ROC) --- Co-Principal Investigator and Steering Committee Member

Davis D, Garberson L, Andrusiek D, Hostler D, Daya M, Pirrallo R, Craig C, Stephens S, Larsen J, Drum A, Fowler R, ROC Investigators (jncluding Pepe PE). A descriptive analysis of emergency medical service systems participating in the Resusciation Outcomes Consortium (ROC) network. Prehospital Emergency Care 2007; 11(4):369-382.

Brasel K, Bulger E, Cook A, et al, ROC Investigators (incl Pepe PE). Hypertonic resuscitation: Design and implementation of a prehospital intervention trial. Journal of the American College of Surgeons 2008; 206(2): 220-232.

Stiell I, Callaway C, Davis D, et al, ROC Investigators (incl Pepe PE). Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods. Part 2: Rationale and methodology for Analyze Later vs. Analyze Early protocol. Resuscitation 2008; 78(2):186-195. PMCID: PMC2614111

Aufderheide TP, Kudenchuk PJ, Hedges JR, Nichol G, Kerber RE, Dorian P, Davis DP, Idris AH, Callaway CW, Emerson, Stiell IG, Terndrup TE, ROC Investigators (including Pepe PE). Resuscitation Outcomes Consortium (ROC) PRIMED cardiac arrest trial methods. Part 1: Rationale and methodology for the impedance threshold device (ITD) protocol. Resuscitation 2008; 78:179-185. NIHMSID: NIHMS81350.

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Newgard CD, Sears GK, Rea TD, et al, ROC Investigators (incl Pepe PE). The Resuscitation Outcomes Consortium epistry-tauma: Design, development, and implementation of a North American Epidemiologic Prehospital Trauma Registry. Resuscitation 2008; 78:170-178. PMCID: PMC2562032

Morrison LJ, Nichol G, Rea TD, Christenson J, Callaway CW, Stephens S, Pirrallo RG, Atkins DL, Davis DP, Idris AH, Newgard CD, ROC Investigators (incl Pepe PE). Rationale, development and implementation of the Resuscitation Outcomes Consortium epistry-cardiac arrest. Resuscitation 2008; 78:161-169. NIHMSID: NIHMS63375.

Nichol G, Thomas E, Callaway CW, et al, ROC Investigators (incl Pepe PE). Regional variation in out-of-hospital cardiac arrest incidence and outcome. Journal of the American Medical Association 2008; 300:1423-1431. PMCID: PMC3187919

Tisherman SA, Powell J, Schmidt TA, et al, ROC Investigators (incl Pepe PE). Regulatory challenges for the Resuscitation Outcomes Consortium. Circulation 2008; 118:1585-1592. PMCID: PMC2757627

Bulger E, Schmidt T, Cook A, Brasel K, Griffiths D, Kudenchuk P, Davis D, Bardarson B, Idris A, Aufderheide T. ROC Investigators (incl Pepe PE).. The random dialing survey as a tool for community consultation for research involving the emergency medicine exception from informed consent. Annals of Emergency Medicine 2009; 53(3):351-353. PMCID: 3005614

Atkins D, Everson-Stewart S, Sears G, et al, ROC Investigators (incl Pepe PE). Epidemiology and outcomes from out-of-hospital cardiac arrest in children: The ROC epistry-cardiac arrest. Circulation 2009; 119(11):1484-1491. PMCID: PMC2679169

Sugarman J, Sitlani C, Andrusiek D, et al, ROC Investigators (incl Pepe PE). G. Is the enrollment of racial and ethnic minorities in research in the emergency setting equitable? Resuscitation 2009; 80(6):644-649. PMCID: PMC2692

Christenson J, Andrusiek D, Everson-Stewart S, Kudenchuk P, Hostler D, Powell J, Callaway C, Bishop D, Vaillancourt C, Davis D, Aufderheide T, Idris A, Stouffer J, Stiell I, Berg R, ROC Investigators (incl Pepe PE). Chest compression fraction determines survival in patients with out-of-hospital ventricular fibrillation. Circulation 2009; 120(13):1241-1247. PMCID: PMC2795631

Newgard C, Rudser K, Atkins D, et al, ROC Investigators (incl Pepe PE). The availability and use of out-of-hospital physiologic information to identify high-risk injured children in a multisite, population-based cohort. Prehospital Emergency Care 2009; 13(4):420-431. PMCID: 3008574

Newgard C, Koprowicz K, Wang H, et al, ROC Investigators (incl Pepe PE). Variation in the type, rate, and selection of patients for out-of-hospital airway procedures among injured children and adults. Acad Emerg Med 2009; 16(23):1269-1276. NIHMSID: NIHMS257400.

Bradley S, Gabriel E, Aufderheide T, Barnes R, et al, ROC Investigators (incl Pepe PE). ROC Investigators. Survival increases with CPR by emergency medical services before defibrillation of out-of-hospital ventricular fibrillation or ventricular tachycardia: Observations from the Resuscitation Outcomes Consortium. Resuscitation 2010; 81(2):155-162. PMCID: PMC2814939

Brooks S, Schmicker R, Rea T, et al, ROC Investigators (incl Pepe PE). Out-of-hospital cardiac arrest frequency and survival; evidence for temporal variability. Resuscitation 2010; 81(2):175-181. PMCID: PMC2815250

Newgard CD, Rudser K, Hedges JR, et Al, ROC Investigators (incl Pepe PE). A critical assessment of the out-of-hospital trauma triage guidelines for physiologic abnormality. Journal of Trauma 2010; 68(2):452-62.

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Rea T, Cook A, Stiell I, Powell J, Bigham B, Callaway C, Chugh S, Aufderheide T, Morrison L, Terndrup T, Beaudoin T, Wittwer L, Davis D, Idris A, Nichol G, ROC Investigators (incl Pepe PE). Predicting survival following out-of-hospital cardiac arrest: Role of the Utstein data elements. Annals of Emergency Medicine 2010; 55(3):249-257. NIHMSID: NIHMS257398.

Newgard C, Schmicker R, Hedges J, Trickett J, Davis D, Bulger E, Aufderheide T, Minei J, Hata S, Gubler D, Brown T, Yelle J, Bardarson B, Nichol G, ROC Investigators (incl Pepe PE). Out-of-hospital time and survival: Assessment of the "Golden Hour" in a North American prospective trauma cohort. Annals of Emergency Medicine 2010; 55(3):235-264.e4. PMCID: 3008652

Weisfeldt M, Sitlani C, Ornato J, et al, ROC Investigators (incl Pepe PE). Survival after application of automatic external defibrillators before arrival of the emergency medical system: Evaluation in the Resuscitation Outcomes Consortium population of 21 million. Journal of the American College of Cardiology 2010; 55(16):1713-1720. PMCID: 3008654

Callaway C, Schmicker R, Kampmeyer M, Powell J., Rea T, Daya M, Aufderheide T, Davis D, Rittenberger J, Idris A, Nichol G, ROC Investigators (incl Pepe PE). Receiving hospital characteristics associated with survival after out-of-hospital cardiac arrest. Resuscitation 2010; 81(6) 524-529. PMCID: PMC2856722

Cudnik M, Schmicker R, Thomas L, et al, ROC Investigators (incl Pepe PE). A geospatial assessment of transport distance and survival to discharge in out of hospital cardiac arrest patients: Implications for resuscitation centers. Resuscitation 2010; 81(5):518-523. PMCID: PMC2856760

Bigham BL, Aufderheide TP, Davis DP, et al, ROC Investigators (incl Pepe PE). Knowledge translation in emergency medical services: A qualitative survey of barriers to guideline implementation. Resuscitation 2010; 81(7):836-840. PMCID: PMC3209799

Hostler D, Thomas EG, Emerson SS, Christenson J, Stiell IG, Rittenberger JC, Gorman KR, Bigham BL, Callaway CW, Vilke GM, Beaudoin T, Cheskes S, Craig A, Davis DP, Reed A, Idris A, Nichol G,

ROC Investigators (incl Pepe PE). Increased survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) epistry-cardiac arrest. Resuscitation 2010; 81(7):826-830. PMCID: PMC2893256

Minei JP, Schmicker RH, Kerby JD, et al, ROC Investigators (incl Pepe PE). Severe traumatic injury: Regional variation in incidence and outcome. Annals of Surgery 2010; 252(1):149-157. NIHMSID: NIHMS257330.

Bigham BL, Koprowicz K, Aufderheide TP, Davis DP, Donn S, Powell J, Suffoletto B, Nafziger S, Stouffer J, Idris A, Morrison LJ, ROC Investigators (incl Pepe PE). Delayed prehospital implementation of the 2005 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiac care. Prehospital Emergency Care 2010; 14(3):355-60. PMCID: PMC3209500

Bulger EM, May S, Brasel KJ, Schreiber M, Kerby JD, Tisherman SA, Newgard C, Slutsky A, Coimbra R, Emerson S, Minei JP, Bardarson B, Kudenchuk P, Baker A, Christenson J, Idris A, Davis D, Fabian TC, Aufderheide TP, Callaway C, Williams C, Banek J, Vaillancourt C, van Heest R, Sopko G, Hata JS, Hoyt DB, ROC Investigators (incl Pepe PE). Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. Journal of the American Medical Association 2010; 304(13):1455-1464. PMCID: 3015143

Weisfeldt ML, Everson-Stewart S, Sitlani C, et al, ROC Investigators (incl Pepe PE).. Ventricular tachyarrythmias following cardiac arrest in public versus home. New England Journal of Medicine 2011; 364:313-321.

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Hostler D, Everson-Stewart S, Rea TD, et al, ROC Investigators (incl Pepe PE). Effect of real-time feedback during cardiopulmonary resuscitation outside hospital: prospective, cluster-randomised trial. British Mecdical Journal 2011; 342:d512. PMCID: PMC3033623

Davis DP, Koprowicz KM, Newgard CD, et al, ROC Investigators (incl Pepe PE). The relationship between out-of-hospital airway management and outcome among trauma patients with Glasgow Coma Scale scores of 8 or less. Prehospital Emergency Care 2011; 15(2):184-92. NIHMSID: NIHMS259872. PMC: In Process

Zive D, Koprowicz K, Schmidt T, Stiell I, Sears G, Van Ottingham L, Idris A, Stephens S, Daya M, ROC Investigators (incl Pepe PE). Variation in out-of-hospital cardiac arrest resuscitation and transport practices in the Resuscitation Outcomes Consortium: ROC Epistry-Cardiac Arrest. Resuscitation 2011; 82(3):277-284. PMCID: PMC3039085

Bulger EM, May S, Kerby JD, et al, ROC Investigators (incl Pepe PE). Out-of-hospital hypertonic resuscitation following traumatic hypovolemic shock: a randomized, placebo controlled trial. Annals of Surgery 2011; 253(3):431-441. PMCID: PMC3015143

Newgard CD, Schmicker RH, Sopko G, Andrusiek D, Bialkowski W, Minei JP, Brasel K, Bulger E, Fleischman RJ, Kerby JD, Bigham BL, Warden CR, ROC Investigators (incl Pepe PE).. Trauma in the neighborhood: A geospatial analysis and assessment of social determinants of major injury in North America. American Journal of Public Health 2011; 101(4):669-677

Bigham BL, Koprowicz K, Rea T, Dorian P et al, ROC Investigators (incl Pepe PE). Cardiac arrest survival did not increase in the Resuscitation Outcomes Consortium after implementation of the 2005 AHA CPR and ECC guidelines. Resuscitation 2011; 82:979-983. NIHMSID: NIHMS289666. PMC:

Cheskes S, Schmicker RH, Christenson J, Salcido DD, Rea T, Powell J, Edelson DP, Sell R, May S, Menegazzi JJ, Van Ottingham L, Olsufka M, Pennington S, Simonini J, Berg RA, Stiell I, Idris A, Bigham B, Morrison L, ROC Investigators (incl Pepe PE). Perishock Pause: an independent predictor of survival from out-of-hospital shockable cardiac arrest. Circulation 2011; 124:158-166. PMCID: PMC3138806

Vaillancourt C, Emerson-Steward S, Christenson J, Andrusiek D, Powell J, Nichol G, Cheskes S, Aufderheide TP, Berg R, Stiell IG, ROC Investigators (incl Pepe PE). The impact of increased chest compression fraction on return of spontaneous circulation for out-of-hospital cardiac arrest patients not in ventricular fibrillation. Resuscitation (2011). doi:10.1016/j.resuscitation.2011.07.011 NIHMSID: NIHMS318162. PMC:

Aufderheide TP, Nichol G, Rea TD, Brown SP, Leroux BG, Pepe PE, Kudenchuk PJ, Christenson J, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clement CM, Craig A, Van Ottingham L, Schmidt TA, Wang HE, Weisfeldt ML, Ornato JP, Sopko G, ROC Investigators. A trial of an impedance threshold device in out-of-hospital cardiac arrest. New England Journal of Medicine 2011; 365:798-806

Stiell IG, Nichol G, Leroux BG, Rea TD, Ornato JP, Powell J, Christenson J, Callaway CW, Kudenchuk PJ, Aufderheide TP, Idris AH, Daya M, Wang HE, Morrison L, Davis D, Andrusiek D, Stephens S, Cheskes S, Schmicker RH, Fowler R, Vaillancourt C, Hostler D, Zive D, Pirrallo RG, Vilke GM, Sopko G, Weisfeldt M, ROC Investigators (incl Pepe PE).. Early versus later rhythm analysis in patients with out-of-hospital cardiac arrest. New England Journal of Medicine 2011; 365(9):787-797

Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, Pepe PE, Rea TD, Schmicker RH, Vaillancourt MD C, Chugh SS, ROC Investigators. Socioeconomic status and incidence of sudden cardiac arrest. Canadian Medical Association Journal 2011; doi: 10.1503/cmaj.101512

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Stiell IG, Brown SP, Christenson J, et al, ROC Investigators (incl Pepe PE). What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation? Critical Care Medicine 2012; 40(4):1192-98. PMCID: PMC3307954 doi: 10.1097/CCM.0b013e31823bc8bb Bulger EM, Guffey D, Guyette FX, et al, ROC Investigators (incl Pepe PE). Impact of prehospital mode of transport after severe injury: A multicenter evaluation from the Resuscitation Outcomes Consortium. Journal of Trauma and Acute Care Surgery 2012; 72(3):567-575. PMCID: PMC3495608

Schmicker RH, Leroux BG, Sears GK, et al, ROC Investigators (incl Pepe PE). Temporal compliance trends in a cluster-randomization with crossover trial of out-of-hospital cardiac arrest. Clinical Trials 2012; 0:1-8. PMCID: PMC3515666

Idris AH, Guffey D, Aufderheide TP, Brown S, Morrison LJ, Nichols P, Powell J, Daya M, Bigham BL, Atkins DL, Berg R, Davis D, Stiell I, Sopko G, Nichol G, and the Resuscitation Outcomes Consortium (ROC) Investigators. The Relationship Between Chest Compression Rates and Outcomes from Cardiac Arrest. Circulation 2012;125:3004-3012.

Wang HE, Devlin SM, Sears GK, et al. ROC Investigators (incl Pepe PE). Regional variations in early and late survival after out-of-hospital cardiac arrest. Resuscitation 2012; 83(11):1343-48. PMCID: PMC3470746

Glover BM, Brown SP, Morrison L, Davis et al, ROC Investigators (incl Pepe PE). Wide variability in drug use in out-of-hospital cardiac arrest: a report from the resuscitation outcomes consortium. Resuscitation 2012; 83(11):1324-30. PMCID: PMC3827891

Wang HE, Szydlo D, Sotouffer JA, et al, ROC Investigators (incl Pepe PE). Endotracheal intubation versus supraglottic airway insertion in out-of-hospital cardiac arrest. Resuscitation 2012; 83(9):1061-1066. PMCID: PMC3733371

Callaway CW, Schmicker RH, Brown SP, et al, ROC Investigators (incl Pepe PE). Early coronary angiography and induced hypothermia are associated with survival and functional recovery after out-of-hospital cardiac arrest. Resuscitation. 2014 Jan 8. pii: S0300-9572(14)00008-2. doi: 10.1016/j.resuscitation.2013.12.028. [Epub ahead of print]

Elterman J, Brasel K, Brown S, et al, ROC Investigators (incl Pepe PE).Transfusion of red blood cells in patients with a prehospital Glasgow Coma Scale score of 8 or less and no evidence of shock is associated with worse outcomes. Journal of Trauma and Acute Care Surgery 2013; 75(1):8-14; discussion 14. PMCID: PMC3828641

Wang HE, Brown SP, MacDonald RD, Dowling SK, Lin S, Davis D, Schreiber MA, Powell J, van Heest R, Daya M. Association of out-of-hospital advanced airway management with outcomes after traumatic brain injury and hemorrhagic shock in the ROC hypertonic saline trial. Emergency Medicine Journal 2013; 31(3):186-91. PMCID: PMC3841245

Rea T, Prince D, Morrison L, Callaway C, Aufderheide T, Daya M, Stiell I, Christenson J, Powell J, Warden C, van Ottingham L, Kudenchuk P, Weisfeldt M, and the ROC Investigators. Association between survival and early versus later rhythm analysis in out-of-hospital cardiac arrest: do agency-level factors influence outcomes? Ann Emerg Med 2014; 64(1):1-8

Zelnick L, Morrison L, Devlin S, Bulger E, Brasel K, Sheehan K, Minei J, Kerby J, Tisherman S, Rizoli S, Karmy-Jones R, van Heest R, Newgard C, and the ROC Investigators (including Pepe PE). Addressing the challenges of obtaining functional outcomes in traumatic brain injury research: missing data patterns, timing of follow-up, and three prognostic models. Journal of Neurotrauma 2014; 31(11):1029-38. PMCID: PMC4043258

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Callaway CW, Schmicker R, Brown SP, Albrich M, Andrusiek DL, Aufderheide TP, Christenson J, Daya MR, Falconer D, Husa R, Idris AH, Ornato JP, Rittenberger JC, Stiell IG, Rac VE, Rea TD, Sears G, and the ROC Investigators (including Pepe PE). Early coronary angiography and induced hypothermia are associated with survival and functional recovery after out-of-hospital cardiac arrest. Resuscitation 2014; 85(5): 657-63. PMCID: PMC4117649

Kudenchuk PJ, Brown SP, Daya M, Morrison LJ, Grunau BE, Rea T, Aufderheide T, Powell J, Leroux B, Vaillancourt C, Larsen J, Wittwer L, Colella MR, Stephens SW, Gamber M, Egan D, Dorian P, and the ROC Investigators (including Pepe PE).. Resuscitation Outcomes Consortium-Amiodarone, Lidocaine or Placebo Study (ROC-ALPS): Rationale and methodology behind an out-of-hospital cardiac arrest antiarrhythmic drug trial. American Heart Journal 2014; 167(5):653-59. PMCID: PMC4014351

Cheskes S, Schmicker RG, Verbeek PR, Salvido DD, Brown SP, Brooks S, Menegazzi JJ, Vaillancourt C, Powell J, May S, Berg RA, Sell R, Idris A, Kampp M, Schmidt T, Christenson J, and the ROC investigators (including Pepe PE). The impact of peri-shock pause of survival from out-of-hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium PRIMED trial. Resuscitation 2014; 85:336-342. PMCID: PMC3944081

Stiell IG, Brown SP, Nichol G, Cheskes S, Vaillancourt C, Callway CW, Morrison LJ, Christenson J, Aufderheide TP, Davis DP, Free C, Hostler D, Stouffer JA, Idris AH, and the ROC Investigators (include Pepe PE). What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients? Circulation 2014;130:1962-70

Minei JP, Fabian TC, Guffey DM, Newgard CD, Bulger EM, Brasel KJ, Sperry JL, MacDonald RD. Increased trauma center volume is associated with improved survival after severe injury: results of a resuscitation outcomes consortium study. Annals of Surgery 2014; 260(3):456-465. PMCID: PMC4153990

Baraniuk S, Tilley BC, del Junco DJ, Fox EE, van Belle G, Wade CE, Podbielski JM, Beeler AM, Hess JR, Bulger EM, Schreiber MA, Inaba K, Fabian TC, Kerby JD, Cohen MJ, Miller CN, Rizoli S, Scalea TM, O’Keeffe T, Brasel KJ, Cotton BA, Muskat P, Holcomb JB and the PROPPR Study Group. Pragmatic randomized optimal platelet and plasma ratios (PROPPR) trial: design, rationale and implementation. Injury 2014; 45(9):1287-1295. PMCID: PMC4137482

Nishiyama C, Brown SP, May S, Iwami T, Koster RW, Beesems SG, Kuisma M, Salo A, Jacobs I, Finn J, Sterz F, Nurnberger A, Smith K, Morrison L, Olasveengen TM, Callaway CW, Do Shin , Grasner J-T, Daya M, Huei-Ming Ma M, Herlitz J, Stromsoe A, Aufderheide TP, Masterson S, Wang H, Christenson J, Stiell I, Davis D, Huszti E, Nichol G. Apples to apples or apples to oranges? International variation in reporting of process and outcome of care for out-of-hospital cardiac arrest. Resuscitation 2014.

Tisherman SA, Schmicker RH, Brasel KJ, Bulger EM, Kerby JD, Minei JP, Powell JL, Reiff DA, Rizoli SB, Schreiber MA. Detailed description of all deaths in both the shock and traumatic brain injury hypertonic saline trials of the Resuscitation Outcomes Consortium. Annals of Surgery 2014. doi: 10.1097/SLA.0000000000000837. [Epub ahead of print] NIHMSID: NIHMS605835. PMC:

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V. National / International Position Papers, Reviews and Chapters: Pepe PE and Hudson LD. Acute Respiratory Failure. In: Current Therapy in Emergency Medicine (1986-1987). Michael L. Callaham, Ed. B.C. Decker, Inc., 1986, Toronto, pp. 30-38. Pepe PE, Acute Post-traumatic respiratory physiology and insufficiency. Surg Clin No America. February 1989;69:157-173. Pepe PE. Whom to Resuscitate. In: Intensive and Critical Care Medicine. JM Civetta, Ed. J.B. Lippincott Co., 1988, pp. 93-102. American College of Emergency Physicians Committee on Emergency Medical Services. Guidelines for Emergency Medical Services Systems. Ann Emerg Med July 1988; 17:742-745. American College of Emergency Physicians Committee on Emergency Medical Services. Guidelines for "Do Not Resuscitate" orders in the prehospital setting. Ann Emerg Med October 1988;17:1106-1108. American College of Emergency Physicians Committee on Emergency Medical Services. Prehospital advanced life support skills, medications and equipment. Ann Emerg Med October 1988;17:1109-1111. Pepe PE. Current standard and future directions of basic and advanced life support. In: Critical Care Review. Robert Taylor (Ed), Society of Critical Care Medicine. Fullerton, CA, 1989, pp. 7-17. Pepe PE. Presumptive diagnosis of death versus who to resuscitate. EMS Medical Director's Handbook. Kuehl E (ed), Mosby, St. Louis, 1989, pp. 275-289. Pepe PE. Medical direction in basic life support. Emergency 1990;22:6. Pepe PE, Copass MK. Prehospital Care. In: American College of Surgeons Committee on Trauma. Early Care of the Injured (1990). E.E. Moore, Ed., B.C. Decker, Inc., Toronto; pp. 34-55. American College of Emergency Physicians Committee on Emergency Medical Services (including Pepe PE). Guidelines for the use of thrombolytic agents in the prehospital setting. American College of Emergency Physicians Distribution Center, September 1990, Dallas, Texas.

Pepe PE. Acute Respiratory Insufficiency. In: The Clinical Practice of Emergency Medicine (1990). Ann L. Harwood-Nuss (Ed), J.B. Lippincott Co., Philadelphia, Chapter 290; pp. 903-907. Pepe PE. Current standard and future directions of advanced cardiopulmonary resuscitation. In: Update in Emergency and Intensive Care. Vincent JL (ed) 1990; Springer-Verlag, Berlin; pp. 565-585. Pepe PE. Prehospital and interhospital transport of the trauma patient. In: Problems in Critical Care. Fromm RE (ed). J.B. Lippincott Co., Philadelphia, Dec. 1990;4:556-569. Pepe PE, Almaguer DA. Emergency medical services personnel and ground transport vehicles. In: Problems in Critical Care. Fromm RE (ed). J.B. Lippincott Co., Philadelphia, Dec. 1990;4:470-476. Pepe PE. Administration of Emergency Medical Services. In: Resident Guide to Pursuing an Academic Career in Emergency Medicine Services. Manning JE, Williams JM (eds). Publication of the Society for Academic Emergency Medicine and the Emergency Medicine Resident's Association, Dallas, TX, 1992, pp. 30-34. Pepe, PE. Infections in the traumatized lung. Curr Concepts Trauma Care, 1983; 6:4-10.

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Pepe PE. Antishock garments: more harm than good J Crit Illness Feb 1992;7(2):166-8. Pepe PE. Establishing priorities for trauma victims. Cortlandt Forum 1992;5:48 NN-00. Pepe PE. An urban approach: City of Houston's Emergency Medical System. In: Implementing an Early Defibrillation Program. Space Labs Medical Biophysical Measurements Series, Redmond, WA, 1992, pp.22-23. Pepe PE, Curka PA. Scene supervision of EMS. In: Quality Management in Prehospital Care. Swor R (ed). C.V.Mosby and Co., St. Louis, 1991, Chapter 18, pp. 203-211. Mattox KL, Pepe PE. Thoracic trauma: General considerations. In: Principles and Practice of Emergency Medicine (3rd Edition). Schwartz G (ed), Lea and Febiger, Philadelphia, 1992, pp.1036-1047. Kuehl AE, MacClean T, Pepe PE. Medical control. In: Principles and Practice of Emergency Medicine, 3rd Edition. Schwartz G (ed), Lea and Febiger, Philadelphia, 1992, pp. 3150-3154. Pepe PE. Prehospital management of trauma. In: Principles and Practice of Emergency Medicine, 3rd Edition. Schwartz G (ed), Lea and Febiger, Philadelphia, 1992, pp. 910-917. Pepe PE. Responding to emergencies - review of the Phillips Petroleum explosion. Council of State Governments. March 1990, Council of State Governments, Louisville, KY; p. 9. Martinez R, Pepe PE, Richardson JD. Blunt chest trauma: early management. Patient Care (August) 1991;25:24-63. Pepe PE. Roots and philosophy of emergency medical services. In: The National EMS Medical Directors Course and Practicum Textbook, Kuehl AE and Ryan JL (Eds). Publication of the EMS AC Foundation Clearwater, FL, 1992, pp.1-8. Pepe PE. Emergency medical services systems and prehospital management of patients requiring critical care. In: Principles and Practice of Medical Intensive Care. Carlson RW (ed). 1993, W.B. Saunders Co. Philadelphia pp.9-25. Bickell WH, Pepe PE. Complications of resuscitation. In: Complications of Trauma. Mattox KL (ed). Churchill Livingstone, New York, 1994; pp. 101-138. Pepe PE, Zachariah BS, and Persse DE. Prehospital critical care services. In: Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed). Springer-Verlag, Berlin, Heidelberg, New York, March 1994, pp. 733-743. Pepe PE and others on the Executive Committee of the National Association of EMS Physicians. Use of warning lights and siren in emergency medical vehicle response and patient transport. Position paper of the National Association of Emergency Medical Services Physicians and the National Association of State EMS Directors. Prehosp Disast Med April-June 1994;9:133-136. Pepe PE and others on the Executive Committee of the National Association of EMS Physicians. National guidelines for statewide implementation of EMS "Do not resuscitate" (DNR) programs. Position paper of the National Association of Emergency Medical Services Physicians and the National Association of State EMS Directors. Prehosp Disast Med April-June 1994;9:137-1139. Pepe PE. Delivery of mechanical ventilation during resuscitation in the prehospital and emergency department settings. In: Principles and Practice of Mechanical Ventilation. Tobin MJ (ed), McGraw Hill, Philadelphia, 1994, pp. 589-602.

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Pepe PE and other members, on the Advanced Cardiac Life Support subcommittee of the American Heart Association: Advanced cardiac life support algorithms and drugs: a 1993 Handbook for adult and pediatric providers. American Heart Association, Dallas, TX 1993. Pepe PE and others on the Advanced Cardiac Life Support subcommittee of the American Heart Association:Textbook of Advanced Cardiac Life Support, American Heart Association, Dallas, TX; 1994. Pepe PE. Resuscitation issues. In: Prehospital Systems and Medical Oversight. Kuehl AE (ed), Mosby Lifeline, St. Louis, 1994, pp. 388-398. Pepe PE and other members, Subcommittee on Advanced Cardiac Life Support, American Heart Association Committee on Emergency Cardiac Care. Instructors Manual for Advanced Cardiac Life Support. Cummins RO and Billi JE (eds). American Heart Association, Dallas, TX 1994. Fowler RL, Pepe PE, Lewis RJ. Shock evaluation and management. In: Basic Trauma Life Support. Campbell JE (ed), 3rd ed., Prentice-Hall 1995, New York, pp. 111-124. Pepe PE, Maio RF. Evolving challenges in prehospital trauma services. In: Research: the Who, What, Why, When and How. Menegazzi JJ (ed). Ferno-Washington, Inc. Wilmington, OH, 1995, pp. 93-113. Pepe PE. Out-of-hospital research in the urban environment. In: Research: the Who, What, Why, When and How. Menegazzi JJ (ed). Ferno-Washington, Wilmington, OH, 1995, pp. 82-92. Pepe PE. Controlled studies in the prehospital setting: a viable, important venue for clinical research. In: Prehospital Care Administration. Fitch JJ (ed). Mosby Lifeline, St. Louis, 1995, pp. 528-532. Becker LB, Pepe PE. Ensuring the effectiveness of community-wide emergency cardiac care. In: Prehospital Care Administration. Fitch JJ (ed). Mosby Lifeline, St. Louis, 1995, pp. 570-587. Pepe PE. Acute respiratory insufficiency. In: Handbook of Emergency Medicine. Harwood-Nuss A, Luten RC (eds). JB Lippincott Co. Philadelphia 1995; pp.445-447. Pepe PE. Advances in American prehospital emergency medical services. In: Current Topics in Intensive Care Bion JF (Ed). W.B. Saunders Co. Ltd., London 1995, pp. 1-20. Pepe PE. ACLS systems and training programs -do they make a difference? Respiratory Care April 1995;40:427-436. Pepe PE and others on the Board of Editors. Emergency Care and Transportation of the Sick and Injured. Crosby LA, Lewallen DG, (Eds.) 6th Edition, American Academy of Orthopedic Surgeons, Chicago, IL 1995. Pepe PE. Preoperative fluid resuscitation for post-traumatic hemorrhage: elemental or detrimental? In: Intensivmedizin 1995. Lawin P, Peter K, Prien T (Eds). Georg Thieme Verlag Stuttgart. New York 1995; pp. 72-77. Grauer K, Ornato JP, Pepe PE. Are you up-to-date on ACLS? Patient Care Aug. 15, 1995;29:32-59. Pepe PE. Outcome analysis of basic and advanced cardiac life support. Anesth Clin of No America December 1995;13:981-997. Pepe PE. The philosophy of fire-based EMS. In: Proceedings of the International Association of Firefighters 1995 Conference on Emergency Medical Services. International Association of Firefighters 1995, Washington D.C. pp. 6-20.

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Pepe PE. Resuscitation decisions: improved criteria for both initiation and termination of resuscitation in the out-of-hospital setting. In Yearbook of Intensive and Emergency Medicine 1996 in Vincent JL (ed) Springer-Verlag, Heidelberg 1996; pp. 793-798. Pepe PE, Warnke WJ, Copass MK. Emergency medical services and systems of out-of-hospital resuscitation. Chapter 30, In: Cardiac Arrest: the Science and Practice of Resuscitation Medicine. Paradis NA, Halperin HR, Nowak RM (Eds). Williams & Wilkins, Baltimore, 1995; pp.581-596. Pepe PE. Fire EMS making cents in Houston. J Emerg Med Services 1996; 21:45-46. Pepe PE. Resuscitation of the patient with major trauma. Curr Opin Crit Care 1996;1:479-486. Pepe PE. Resuscitation decisions. In: Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed). Springer-Verlag, Berlin 1996;793-798. Pepe PE (contributor). Thrombolytic therapy study. In: Paramedic Protocols. Westfal RE (Ed), McGraw Hill, N.Y.1996; pp. 142-144. Pepe PE. Acute respiratory insufficiency. Part II Pulmonary Disease. In: The Clinical Practice of Emergency Medicine, second edition. Harwood-Nuss AL, Linden CH, Luten RC, Shepherd SM, Wolfson AB (eds). Lippincott-Raven Publishers, Philadelphia 1996; pp.636-640. Pepe PE and others on the Basic Life Support Subcommittee of the Emergency Cardiac Care Committee of the American Heart Association. Instructor’s Manual: Basic Life Support. American Heart Association, Dallas, Texas 1997. Pepe PE. Initial links in the chain of recovery for brain attack in access, prehospital care, notification and transport. In: National Institute of Neurological Disorders and Stroke: Setting New Directions for Stroke Care. Marler JR, Jones PW, Emr M (eds). National Institutes of Health, August, 1997; Bethesda, MD, pp. 17-28. Pepe PE. Prehospital emergency medical care panel recommendations. In: National Institute of Neurological Disorders and Stroke: Setting New Directions for Stroke Care. Marler JR, Jones PW, Emr M (eds). National Institutes of Health, August, 1997; Bethesda, MD, pp. 147-150. Pepe PE, Eckstein M. Reappraising the prehospital care of the patient with major trauma. Emerg Med Clin No America, Feb 1998; 16:1-15. Pepe PE. Ensuring the Chain of Recovery for Stroke in Your Community. In: Simposio Mostra Anestesia Rianimazione e Terapia Intensiva, Braschi A, Gattinoni L, Pesenti A, Raimondi F (eds). Springer-Verlag, Milano 1998; pp. 66-71. Pepe PE. Eckstein M. Re-appraising the prehospital care of the patient with major trauma. Emerg Clinics No America February 1998;16(1):1-15. Pepe PE. Prehospital Interventions for trauma: helpful or harmful? The American Point of View. Curr Opin Crit Care 1998;4:412-416. Pepe PE. Preoperative fluid resuscitation for presumed post-traumatic hemorrhage: elemental or detrimental? In: Simposio Mostra Anestesia Rianimazione e Terapia Intensiva, Braschi A, Gattinoni L, Pesenti A, Raimondi F (eds). Springer-Verlag, Milano 1998; pp. 78-83. Nordeman LJ, Pepe PE. Improved criteria for disregarding resuscitation efforts following cardiopulmonary resuscitation. In: Simposio Mostra Anestesia Rianimazione e Terapia Intensiva, Braschi A, Gattinoni L, Pesenti A, Raimondi F (eds). Springer-Verlag, Milano 1998; pp. 240-244.

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Pepe PE and others on the Basic Life Support Subcommittee of the Emergency Cardiac Care Committee of the American Heart Association. Providers’ and Instructors’ Manual: Heartsaver-AED for the Lay Rescuer and First Responder. American Heart Association, Dallas, Texas 1998. Valadka AB, Pepe PE. Prehospital management of the head-injured patient. In: Traumatic Brain Injury, Marion DW (Ed), Thieme Medical Publishers, Inc., New York, 1999; pp 55-65. Pepe PE. Prehospital management of trauma. In: Principles and Practice of Emergency Medicine, 4th Edition. Schwartz GR (ed), Williams and Wilkins, Baltimore, 1999 pp. 217-222. Handbook of Emergency Cardiovascular Care. Hazinski MF, Cummins RO, Field J. (eds) American Heart Association 1999, Dallas (contributions from Basic Life Support Subcommittee, including Pepe PE). Fowler RL, Pepe PE, Lewis RJ. Shock evaluation and management. In: Basic Trauma Life Support. Campbell JE (ed), 4th Edition, Brady/Prentice-Hall Health, Upper Saddle River, NJ, 2000, pp. 95-106. Pepe PE (contributor). American Heart Association Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care - international consensus on science. August 22, 2000; 102 (Supplement I)l 1-384. Pepe PE (contributor). Basic Life Support and Special Situations. American Heart Association Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care - international consensus on science. August 22, 2000; 102 (Supplement I)l 1-384. Pepe PE. Acute respiratory insufficiency. In: The Clinical Practice of Emergency Medicine, third edition. Harwood-Nuss AL, Linden CH, Luten RC, Shepherd SM, Wolfson AB (eds). Lippincott-Raven Publishers, Philadelphia 2001, Chapter 130, pp 657-663. Maull KI, Pepe PE. The patient with penetrating injuries. In Prehospital Trauma Care. Soreide E, Grande C, Lippert FK, Fallon WF (eds), Dekker Publishing; New York 2001. pp 403-419. Pepe PE. Current issues in resuscitative trauma management: an overview. Curr Opin Crit Care. Dec 2001;7(6):409-412. Fowler R, Pepe PE. Fluid resuscitation in the patient with major trauma. Curr Opin Anaesth. April 2002; 15:173-178. Benitez FL, Pepe PE. On-scene supervision. EMS Medical Director's Handbook. Kuehl E (ed), Mosby, St. Louis, 2002. Chapter 28, pp 330-339. Pepe PE. Resuscitation issues. In: Prehospital Systems and Medical Oversight. Kuehl AE (ed), Mosby Lifeline, St. Louis, 2002. Chapter 21, pp 245-260. Pepe PE. The pneumatic anti-shock garment. In: Prehospital Systems and Medical Oversight. Kuehl AE (ed), Mosby Lifeline, St. Louis, 2002. Chapter 46, pp 525-529. Pepe PE. Media. In: Prehospital Systems and Medical Oversight. Kuehl AE (ed), Mosby Lifeline, St. Louis, 2002. Chapter 41, pp 481-492. Benitez FL, Pepe PE. Role of the physician in prehospital management of trauma: North American perspective. Curr Opin Crit Care. December 2002. 8(6):551-558. Pepe PE. Management of trauma: changing perspectives. Curr Opin Crit Care. 8(6):549-550, December 2002.

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Pepe PE. Executive Summary -- National Institute of Neurological Disorders and Stroke Symposium: Improving the Chain of Recovery for Acute Stroke in Your Community. Publication of the National Institutes of Health (NIH) National Institute for Neurological Disorders and Stroke (NINDS); September 2003; pp. v – vii. Pepe PE and others (Task Force IV) for National Institute of Neurological Disorders and Stroke Symposium: Improving the Chain of Recovery for Acute Stroke in Your Community. Templates for organizing stroke triage. Publication of the National Institutes of Health (NIH) National Institute for Neurological Disorders and Stroke (NINDS); September 2003; 41-70. Pepe PE, Wigginton JG, Fowler RL. Immediate defibrillation for out-of-hospital ventricular fibrillation. In: 2003Yearbook of Intensive and Emergency Medicine in Vincent JL (ed) Springer-Verlag, Berlin 2003; pp. 472-478. Advanced Disaster Life Support. (Pepe PE, Co-Editor). American Medical Association 2003, Chicago. Basic Disaster Life Support. (Pepe PE, Co-Editor). American Medical Association 2003, Chicago Core Disaster Life Support. (Pepe PE, Co-Editor). American Medical Association 2004, Chicago. Roppolo LP, Wigginton JG, Pepe PE. Emergency ventilatory management as a detrimental factor in resuscitation practices and clinical research efforts. 2004 Yearbook of Intensive Care and Emergency Medicine in Vincent JL (ed) Springer-Verlag, Heidelberg, 2004; pp. 139-151. Pepe PE, Roppolo LP, Cobb LA. Successful systems for out-of-hospital resuscitation. In: Cardiopulmonary Arrest. Ornato JP and Peberdy MA, (eds); Humana Press, Totowa, NJ 2004; pp 649-681. Wigginton JG, Benitez FL, Pepe PE. Endotracheal intubation in the field: Caution needed. Hospital Medicine February 2005; 66: 91-94. Wigginton JL, Miller AH, Benitez FL, Pepe PE. Mechanical devices for cardiopulmonary resuscitation. Curr Opin Crit Care 2005:11:219-223. Pepe PE, Roppolo LP, Fowler RL. The detrimental effects of ventilation during low-blood-flow states. Curr Opin Crit Care 2005;11:212-218. Fowler RL, Pepe PE, Moore PE. Media and communications preparedness for terrorist events. In: Medical Response to Terrorism. Keyes DC, Burstein JL, Schwartz RB, Swienton RE (Eds) Lippincott Williams and Wilkins, Philadelphia 2005; pp 320-328. Wigginton JG, Roppolo LP, Pepe PE. Cardiopulmonary resuscitation (CPR) instructions provided by emergency medical dispatchers. In: 2005 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Heidelberg 2005; pp 280-289. Pepe P and Bierens J. Overview: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg 2006 pp. 312-314. Pepe P and Bierens J. Consensus and recommendations: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2006 pp. 314-323. Wigginton J, Pepe P, Mann D, Persse D and Sirbaugh P. The critical role of laypersons and their actions in drowning incidents: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2006 pp. 323-327.

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Wenzel V and Pepe P. Advanced life support: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2006 pp. 348-351. Nemiroff M and Pepe P. Termination of resuscitation efforts in drowning: Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2006 pp. 363-368. Idris A, Berg R, Bierens, et al (incl Pepe P). Recommended guidelines for uniform reporting of drowning: the Utstein Style. Task Force on Resuscitation. In: The Handbook on Drowning, the Final Report of the World Congress on Drowning. Bierens JLM (ed), Springer-Lager, Heidelberg, 2006 pp. 377-385. Pepe PE, Rinnert KJ, Wigginton JG. Disaster medicine. In: Update in Intensive Care and Emergency Medicine; Intensive Care Medicine in 10 Years. Fink M, Suter PM, Sibbald WJ (eds) Springer-Verlag, Heidelberg 2006,Vol 43 pp. 257-270. Rinnert KJ, Wigginton JG, Pepe PE. Catastrophic anachronisms: the past, present and future of disaster medicine In: 2006 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Berlin Heidelberg 2006; pp 761-772. Wigginton JG, Pepe PE, Idris AH. Sex-related differences in response to global ischemic insult and

treatment. In: 2007 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-

Verlag, Berlin Heidelberg 2007; 880-888. Pepe PE and others on the Editorial Board, American Medical Association publication, Disaster Medicine and Public Health Preparedness. Breaking down territorial boundaries: a call to all professions and disciplines. Disaster Med Public Health Prep July 2007;1:3-6. Roppolo LP, Saunders T, Pepe PE, Idris AH. Layperson training for cardiopulmonary resuscitation: when less is better. Curr Opin Crit Care June 2007;13:256-260. Pepe PE. Evolution and revolution in cardiopulmonary resuscitation: how technology is getting us back to the basics. Curr Opin Crit Care June 2007;13:253-255. Pepe PE. Foreword. The emergency medicine perspective. In: Trauma (Vol. 1): Emergency resuscitation, perioperative anesthesia, surgical management and Trauma (Vol. 2): Critical care. Wilson WC, Grande CM, Hoyt DB (eds). Informa Healthcare Publishers, 2007, New York, NY. Pepe PE and others on the Editorial Board, American Medical Association publication, Disaster Medicine and Public Health Preparedness. Breaking down territorial boundaries: a call to all professions and disciplines. Disaster Med Public Health Prep 2007;1:3-6. Pepe PE. In-hospital care – extension of EMS: Reversing the traditional perspective. J Emerg Med Services Special Supplement (State of the Science); October 2007: 4. Fowler RL, Pepe PE, Stevens JT. Shock evaluation and management. In: International Trauma Life Support. Campbell JE (ed), 6th Edition, Brady/Prentice-Hall Health, Upper Saddle River, NJ, 2008, pp. 118-135. Wigginton JG, Pepe PE, Aversano TR. The role of automated external defibrillators in acute heart failure patients. In: Textbook of Severe Acute Heart Failure Syndromes: A Practical Approach for Physicians. Mebazza A, Gheorghiade M, Zannad FM, and Parrillo JE (Eds), Springer-Verlag, London, 2008; pp.827-836.

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Pepe PE, Copass MK, Fowler RL, Racht EM, Medical direction of emergency medical services systems. In Emergency Medical Services: Clinical Practice and Systems Oversight, Cone DC, Fowler R, O’Connor RE (eds). Textbook of the National Association of EMS Physicians, Kendall-Hunt Publications, Dubuque, IA, 2009; pp 22-52. Pepe PE, Pepe LL, Davis R, Sergel RH. EMS physicians as public spokespersons: ten golden rules for public speaking and dealing with the news media. In: Emergency Medical Services: Clinical Practice & Systems Oversight, Cone DC, Fowler R, O’Connor RE (eds). Textbook of the National Association of EMS Physicians, Kendall-Hunt Publications, Dubuque, IA 2009; pp. 134-150. Eckstein M, Racht EM, Pepe PE. Termination of resuscitation in the out-of-hospital setting. In: Emergency Medical Services: Clinical Practice and Systems Oversight, Cone DC, Fowler R O’Connor RE (eds). Textbook of the National Association of EMS Physicians, Kendall-Hunt Publications, Dubuque, IA, 2009; Chapter 43: pp. 468-480. Pepe PE, Fowler RL, RInnert KJ. Education of the emergency medical services physician. In: Emergency Medical Services: Clinical Practice and Systems Oversight, Cone DC, Fowler R, O’Connor RE (eds). Textbook of the National Association of EMS Physicians, Kendall-Hunt Publications, Dubuque, IA, 2009; pp. 53-62.

Institute of Medicine of the National Academies Board of Health Policy Sciences, Committee on Preparedness for a Nuclear Event (including Pepe PE). Assessing medical preparedness to respond to terrorist nuclear event. Benjamin GC, McGeary M, McCutcheon, Eds. National Academies Press, Washington, DC, 2009; pp.1-191. Metzger JC, Eastman AL, Pepe PE. 2008 Year in review: Critical Care – trauma. Critical Care October 2009; 13:226 (doi:10.1186/cc7960) Roppolo LP, Pepe PE, Bobrow BJ. The role of gasping in resuscitation. In: The Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Berlin Heidelberg 2010; pp. 83-95. Metzger JC, Eastman AL, Pepe PE. Year in review 2009: Critical Care – cardiac arrest, trauma and disasters. Critical Care November 5, 2010:14:242 http://ccforum.com/content/pdf/cc9302.pdf Roppolo LP, Wigginton JG, Pepe PE. Intravenous fluid resuscitation for the trauma patient. Curr Opin Crit Care 2010;16(4):283-288. Wigginton, JG, Idris AH, Pepe PE. Evolving rationale for minimally-interrupted chest compressions during cardiopulmonary resuscitation. In: The Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Berlin Heidelberg 2011; pp.220-230. doi: 10.1007/978-3-642-18081-1 Metzger JC, Eastman AL, Pepe PE. Year in review 2010: Critical Care – cardiac arrest and cardiopulmonary resuscitatin. Critical Care 2011;15:239 http://ccforum.com/content/15/6/239 Lippmann MJ, Salazar GA, Pepe PE. Prehospital resuscitative interventions: elemental or detrimental? In: 2012 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Berlin Heidelberg 2012; pp. 483-492. Pepe PE. Foreword. Law Enforcement Responder: Principles of Emergency Medicine, Rescue and Force Protection. Stair RG, Polk DA, Shapiro GL, Tang N (eds). Jones and Bartlett Learning, Burlington MA, 2012; pp. xxi – xxii. Eastman AL, Pepe PE. A review of transfusion therapy: Clinical Principles and Practice, 3rd Edition, Crit Care July 2012;16:315.

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Pepe PE and Nichols S. Event medicine: an evolving subspecialty of emergency medicine. In: 2013 Yearbook of Intensive Care and Emergency Medicine. Vincent JL (ed) Springer-Verlag, Berlin Heidelberg 2013; pp. 37-47. Pepe PE, Pepe LB, Davis RM, Mann P, Whitmeyer R. EMS Physicians as public spokespersons. Chapter 15, Volume 2; Section II: Clinical Leadership and Oversight: Emergency Medical Oversight: In: Emergency Medical Oversight: Clinical Practice and Systems Oversight, 2nd Edition. Cone DC, Brice JH, Delbridge TR, Myers JB (eds).Wiley and Sons, Inc., Hoboken NJ, USA, 2015; pp. 146 – 159. Companion Website: www.Wiley.com\go\Cone\NAEMSP Pepe PE, Roppolo LP, Fowler RL. Prehospital endotracheal intubation: elemental or detrimental? In: 2015 Annual Update in Intensive Care and Emergency Medicine. Vincent JL (ed) Springer International Publishing Switzerland and BioMed Central Ltd. 2015;155-166. DOI 10.1007/978-3-319-13761-2_12 Fowler RL, Pepe PE, Stevens JT, Ramirez ML, Mell H. Shock. In: International Trauma Life Support. Campbell JE, Alson RL (eds), 8th Edition, Pearson Education, Inc., New York, NY; 2016, Chapter 8, pp. 153-176. ISBN-10: 0-13-413079-0; ISBN-13: 978-0-13-413079-8 Klein KR, Pepe PE. Pre- and Inter-hospital transport of the critically ill and injured. In the Oxford Textbook of Critical Care, 2nd edition, Webb A, Angus D, Finfer S, Gattinoni L, Singer M (eds), Oxford University Press, Oxford, UK, Published: 25 July 2016;19-23. (1,824 Pages) ISBN: 9780199600830

Pepe PE. Dispatcher-assisted CPR. In: Exploring Strategies to Improve Cardiac Arrest Survival:

Proceedings of a Workshop. National Academies of Sciences, Engineering and Medicine McCoy MA

and Schultz A (Rapporteurs), National Academies Press, 2016; pp.5-9 to 5-10. ISBN 978-0-309-

45191-8 (128 pages).

VI. TEXTBOOK Editor-in-Chief Lawner BJ, Slovis CM, Fowler R, Pepe P, Mattu A (Editors). Avoiding Common Prehospital Errors. Wolters and Kluwer Health, Lippincott Williams and Williams, Philadelphia, 2013 VII. LETTERS

Pepe PE, Hudson LD, Carrico CJ. PEEP to prevent adult respiratory distress syndrome. N Engl J Med 1984;311:1321-1322. Pepe PE, Bickell WH, Mattox KL. MAST and the Trauma Score. Ann Emerg Med 1985:15:189-190. Pepe PE. Orange county largest defibrillation program? Fire Chief Nov. 1990; pp. 9. Brown CG, Martin DR, Pepe PE. High-dose epinephrine in cardiopulmonary resuscitation. N Engl J Med 1993;328:735-736. Pepe PE. Does EMS belong in the fire service? Emerg Med Services May 1994;23:16-17. Bickell WH, Pepe PE, Mattox KL. Immediate versus delayed fluid resuscitation in patients with trauma. N Engl J Med March 9, 1995;332:681-683.

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Caffrey-Villari S, Pepe PE. Public use of automated external defibrillators. N Engl J Med. February 20, 2003, 348(8):755-756. Aufderheide TP, Craig A, Leroux BG for the authors (include Pepe PE). An impedance threshold device in out-of-hospital cardiac arrest. N Engl J Med January 12, 2012;366(2):186-188. Pierce AE, Roppolo LP, Owens P, Pepe PE, Idris AH. The need to resume chest compressions immediately after defibrillation attempts. Resuscitation 2015;89 (in press).

VII. Abstracts - Scientific Paper Presentations (limited to 1991 - present) Pepe PE, Kelly JE, Ivy MV, Matsumoto CM and Clayton RL. Resource utilization and impact of using fire apparatus for a fully-integrated EMS first-responder program. Ann Emerg Med 1991;20:488. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 15, 1991, Washington, D.C. Curka PA, Pepe PE, Ginger VF and Sherrard RC. Computer-aided EMS priority dispatch: Ability of a computerized triage system to safely spare paramedics from responses not requiring advanced life support. Ann Emerg Med 1991;20:446. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 12, 1991, Washington, D.C. Hoekstra JW, Banks JR, Martin DR, Cummins RO, Pepe PE, Stueven HA, Jastremski M, Gonzalez E, Brown CG. The effect of EMT-Defibrillation on time to the therapeutic interventions during cardiac arrest. Ann Emerg Med 1991;20:446-447. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 12, 1991, Washington, D.C. Spivey WH, Abramson NS, Safar P, et al. Correlation of blood pressure with mortality and neurologic recovery in comatose post resuscitation patients. Ann Emerg Med 1991;20:453. Presented May 13, 1991 at the Annual Meeting of the Society for Academic Emergency Medicine, Washington, D.C. Pepe PE, Mattox KL, Curka PA, Ginger VF and Sherrard RC. Computer-aided Emergency Medical Services priority dispatch triage system. Prehosp Disast Med 1991 6;197. Presented at the 7th World Congress on Emergency and Disaster Medicine, May 14, 1991, Montreal, Canada. Pepe PE, Mattox KL, Ivy MV and Kelly JE. Fiscal and operational impact of using fire apparatus for a fully-integrated EMS first-responder program. Prehosp Disaster Med 1991 6;218. Presented at 7th World Congress on Emergency and Disaster Medicine, May 14, 1991, Montreal, Canada. Meskill DJ, Curka PA, Pepe PE, Steich WG and Gray GD. Diminishing stretcher-related back injuries in EMS personnel. Prehosp Disaster Med 1991;6:391. Presented at the 7th Annual Meeting of the National Association of EMS Physicians, June 14, 1991, Orlando, FL. Durham LA, Richardson RJ, Wall MJ, Pepe PE and Mattox KL. Emergency center thoracotomy: impact of prehospital resuscitation J Trauma 1991;31:1033. Presented at the 51st Annual Meeting of the American Association for the Surgery of Trauma, Philadelphia, Sept. 6, 1991. Martin RR, Bickell WH, Pepe PE, Mattox KL. Prospective evaluation of preoperative fluid resuscitation in hypotensive patients with penetrating truncal injury: a preliminary report. J Trauma 1991;31:1033. Presented at the 51st Annual Meeting of the American Association for the Surgery of Trauma, Philadelphia, Sept. 6, 1991.

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Mann DM, Pepe PE. Achieving mass public CPR education in a large metropolitan city: stepping-stones to success. Proceedings of the American Heart Association Emergency Cardiac Care Update, April 1992, pp. 30-31. Presented at the Emergency Cardiac Care Update Conference, April 10, 1992, Seattle, WA. Pepe PE, Mann DM. Definitive criteria for the initiation and termination of resuscitation efforts in the prehospital setting. Proceedings of the American Heart Association Emergency Cardiac Care Update, April 1992, pp. 61-62. Presented at the Emergency Cardiac Care Update Conference, April 11, 1992, Seattle, WA. Pepe PE, Mattox KL, Duke JH, et al. Impact of full-time-specialized physician supervision on the success of an EMS system. Crit Care Med April 1992;20:S33. Presented May 26, 1992 at the Annual Symposium of the Society for Critical Care Medicine, San Antonio, TX. Levine RL, Pepe PE, Fromm RE, Curka PA and Clark PS. Prospective analysis of diurnal variations in out-of-hospital cardiac arrest. Crit Care Med April 1992;20:S26. Presented May 26, 1992 at the Annual Symposium of the Society for Critical Care Medicine, San Antonio, TX. Pepe PE, Levine RL, Fromm RE, Curka PA and Clark PS. Cardiac arrest presenting with rhythms other than ventricular fibrillation: contribution of resuscitation efforts toward total survivorship. Crit Care Med 1992;20:S85. Presented May 26, 1992 at the Annual Symposium of the Society for Critical Care Medicine, San Antonio, TX. Pepe PE, Curka PA, Zachariah BS, Wall MJ, Mattox KL and Ginger VF. Urban trauma: diurnal variations in the incidence, severity and geographical distribution of various mechanisms of injury. Ann Emerg Med 1992;21:618. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 27, 1992 in Toronto, Canada. Curka PA, Almeida SL, Pepe PE, Zachariah BS. Diminishing occupational exposure to communicable diseases in an EMS system. Ann Emerg Med 1992;21:600. Presented at Annual Meeting of the Society for Academic Emergency Medicine, May 27 1992, Toronto, Canada Pepe PE, Levine RL, Fromm RE, Curka PA, Clark PS. Cardiac arrest patients presenting with asystole or ECG complexes without pulses: Contribution of resuscitation efforts toward total survivorship. Ann Emerg Med 1992;21:633. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 27, 1992 in Toronto, Canada. Taillac PP, Pepe PE, Zachariah BS, and Curka PA. The epidemiology, type and severity of pediatric gunshot wounds in a large urban center. Ann Emerg Med 1992;21:1045. Presented at the Annual Meeting of the American College of Emergency Physicians, September 16, 1992, Seattle, WA. Pepe PE, Mattox KL, Bickell WH, Wall MJ. Deliberate fluid restriction in post-traumatic hypovolemic hypotension. Proceedings of the 5th International Conference on Hypertonic Resuscitation, May 5, 1992 Galveston, TX. Pepe PE, Zachariah BS, Taillac PP, Curka PA, Wall MJ, Brandt M, Mattox KL. The epidemiology, demography, nature and severity of juvenile gunshot wounds in a large municipality. Proceedings of the National Conference on Pediatric Trauma. Presented September 27, 1992, Indianapolis, IN Zachariah BS, Curka PA, Pepe PE, Riggs R, Olsen B. The use of guidelines to reduce the number of significantly ill patients not transported by EMS. So Med J 1992;85 (supplement 3):28. Presented at the Annual Meeting of the Southern Medical Association, November 1992, San Antonio, TX.

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Taillac PP, Pepe PE, Zachariah BS, and Curka PA. The epidemiology, type and severity of pediatric gunshot wounds in a large urban center. So Med J 1992;85 (supplement 3):25. Presented at the Annual Meeting of the Southern Medical Association, November, 1992, San Antonio, TX. Ghusn HF, Teasdale TA, Pepe PE, Ginger VF. Resuscitation training and equipment in nursing homes: impact on outcome. Gerontologist 1991. Ghusn HF, Teasdale TA, Pepe PE, Ginger VF. Nursing home elders had a similar survival after cardiac arrest as elders living in the community. J Am Geriat Soc 1991. Fromm RE, Levine R, Pepe PE. Circadian variation in requests for helicopter transport of cardiac patients. Chest 1992;102:176s. Presented at the Annual Meeting of the American College of Chest Physicians, October 1992, Chicago, IL. Pepe PE, Kimball KT, Bonnin MJ, Clark PS. On-scene restoration of spontaneous circulation: the key predictor of survival from out-of-hospital cardiac arrest. J Am Coll Card 1993;21:103A. Presented at the American College of Cardiology Annual Meeting, Anaheim, CA, March 15, 1993. Pepe PE, Brown CG, Bonnin MJ, et al. Prospective validation of criteria for on-scene termination of resuscitation efforts after out-of-hospital cardiac arrest. Ann Emerg Med May 1993;22:884-885. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 18, 1993, San Francisco, CA. Martin DR, Persse D, Brown CG, Jastremski M, Cummins RO, Pepe PE, Gonzalez E, Stueven H. Relation between initial post-resuscitation systolic blood pressure and neurologic outcome following cardiac arrest. Ann Emerg Med May 1993;22:917. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 18, 1993, San Francisco, CA. Martin DR, Soria DN, Brown CG, Pepe PE, Gonzalez E, Jastremski M, Stueven H, Cummins RO. Agreement between paramedic estimated weights and subsequent hospital measurements in adults with out-of-hospital cardiac arrest. Prehosp Disast Med 1993;8 (Supplement 2) June 1993;8:S74. Presented at the Annual Meeting of the National Association of EMS Physicians, June 12, 1993, Minneapolis, MN. Curka PA, Pepe PE, Zachariah BS, Gray GD and Matsumoto C. The incidence, source, and nature of complaints received in a large urban EMS system. Prehosp Disast Med (Supplement 2) June 1993;8:S73. Presented at the Annual Meeting of the National Association of EMS Physicians, June 12, 1993, Minneapolis, MN. Pepe PE, Kimball KT, Bonnin MJ, Clark PS, Zachariah BS. On-scene restoration of spontaneous circulation: the key predictor of survival. Acad Emerg Med 1994;1:313. Presented at the Combined European Medical Research Society /Society for Academic Emergency Medicine Meeting, September 17, 1993 in Cambridge, England. Pepe PE, Levine RL, Zachariah BS, Fromm RE, Kimball KT, Curka PA. Gender-related differences in the presentation and outcome of out-of-hospital cardiac arrest. Acad Emerg Med May-June 1994;1:314. Presented at the Combined European Medical Research Society / Society for Academic Emergency Medicine Meeting, September 17, 1993 in Cambridge, England. Zachariah BS, Pepe PE, Curka PA. Analysis of medication usage in an urban EMS system. Acad Emerg Med May-June 1994;1:315. Presented at the European Medical Research Society-Society for Academic Emergency Medicine Joint Meeting, Sept. 17, 1993, Cambridge, England. Pepe PE, Cobb LA, Persse DE, Menegazzi JJ, Fahrenbruch CE, Copass MK, Zachariah BS. Improved criteria for waiving resuscitation efforts for out-of-hospital primary cardiac arrest. Ann Emerg Med 1994;23:619. Proceedings of the American Heart Association 1994 Emergency Cardiac Care Update. Presented at the Biannual ECC Update, May 13, 1994, Richmond, VA.

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Martin DR, Persse DE, Brown CG, Keseg D, Jastremski M, Pepe PE. Comparison of on-line versus off-line medical control in out-of-hospital cardiac arrest. Ann Emerg Med 1994;23:619. Presented at the American College of Emergency Physicians Research Forum, March 20, 1994 in San Diego, CA. Craig MT, Abramson NS, Safar P, et al. Deferred consent in a multicenter prehospital clinical trial. Ann Emerg Med 1994;23:619-620. Presented at the American College of Emergency Physicians Research Forum, March 20, 1994 in San Diego, CA. Zachariah BS, Pepe PE, Persse DE and Curka PA. The effect of warning lights and sirens on EMS response intervals. Ann Emerg Med 1994;23:637. Presented at the American College of Emergency Physicians Research Forum, March 20, 1994 in San Diego, CA. Pepe PE. Advanced cardiac life support --does it really work? Proceedings of the International Resuscitation Research Conference 1994. Presented at the IRRC, May 6, 1994 in Pittsburgh, PA. Pepe PE. Rationale for prehospital clinical resuscitation research. Proceedings of the International Resuscitation Research Conference 1994. Presented at the IRRC, May 7, 1994 in Pittsburgh, PA. Pepe PE. Evolving directions in the early management of post-traumatic hemorrhage. Proceedings of the International Resuscitation Research Conference 1994. Presented at the IRRC, May 7, 1994 in Pittsburgh, PA. Pepe PE. Improved criteria for both termination and waiver of resuscitation efforts. Proceedings of the International Resuscitation Research Conference 1994. Presented at the IRRC, May 7, 1994 in Pittsburgh, PA. Pepe PE. Evolving directions in the prehospital and emergency department management of severe trauma. Proceedings of the International Resuscitation Research Conference 1994. Presented at the IRRC, May 6, 1994 in Pittsburgh, PA. Pepe PE, Persse DE, Zachariah BS, Shook JE, Post R and Kimball KT. The effect of a municipal gun responsibility ordinance on firearm injury deaths in minors. Acad Emerg Med March-April 1994;1:A2-3. Presented at the Society for Academic Emergency Medicine, May 9, 1994 in Washington, D.C. Pepe PE, Widmeyer, RP, Matthew WJ, Mattox KL, Zachariah BS and Whitten GB. The effect of violence-related injury on public resources and the public health care system. Acad Emerg Med March-April 1994;1:A83. Presented at the Society for Academic Emergency Medicine, May 12, 1994 in Washington, D.C. Zachariah BS, Kim D, Persse DE, Snyder E and Pepe PE. Training in automatic external defibrillation use: How much is enough? Acad Emerg Med March-April 1994;1:A87. Presented at the Society for Academic Emergency Medicine, May 12, 1994 in Washington, D.C. Bickell WH, Wall MJ, Pepe PE, et al. A comparison of immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injury. Acad Emerg Med March-April 1994;1:A1. Presented at the Society for Academic Emergency Medicine, May 9, 1994 in Washington, D.C

**Winner of Best Scientific Presentation Award**. Pepe PE, Brown CG, Bonnin MJ, et al. Prospective validation of criteria for on-scene termination of resuscitation efforts after out-of-hospital cardiac arrest. Acad Emerg Med 1994;1:315. Presented at the Combined European Medical Research Society / Society for Academic Emergency Medicine Meeting, September 17, 1993 in Cambridge, England.

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Biggers W, Zachariah BS, Pepe PE. Emergency medical services collisions in an urban system. Prehosp Disast Med Jul-Sept. 1994;9 (suppl 2):S54. Presented at the Tenth Annual Conference and Scientific Assembly of the National Association of EMS Physicians, August 12, 1994, Portland, OR. Sirbaugh PE, Ward MA, Snyder E, Pepe PE, Shook JE. Epidemiology and outcome of out-of-hospital pediatric cardiopulmonary arrest. Presented at the American academy of Pediatrics 1994 Annual Meeting, Dallas, TX. Pepe PE, Persse DE, Zachariah BS, Shook JE, Post R and Kimball KT. The effect of a municipal gun responsibility ordinance on firearm injury deaths in minors. Proceedings of the 1994 National Trauma Symposium. Presented November 18, 1994 at the National Trauma Symposium, Baltimore, MD. Abramson NS, Safar P, Sutton-Tyrrell K and other members of the Brain Resuscitation Clinical Trials III Group. Ann Emerg Med January 1995;25:130. Presented at the Annual Meeting of the American College of Emergency Physicians Research Forum, Feb. 25, 1995, San Francisco, CA. Key CB, Pepe PE, Sirbaugh PE, Shook JE, Kimball KT. Does endotracheal intubation affect outcome in out-of-hospital pediatric cardiac arrest? Acad Emerg Med May 1996;3:404. Presented at the Annual meeting of the Society for Academic Emergency Medicine, May 5, 1996 in Denver, Colorado. Pepe PE, Key CB, Sirbaugh PE, Shook JE, Kimball KT. Distinct criteria for the termination of resuscitation efforts for cardiopulmonary arrest in children. Acad Emerg Med May 1996;3:475. Presented at the Annual meeting of the Society for Academic Emergency Medicine, May 7, 1996 in Denver, Colorado. Sirbaugh PE, Pepe PE, Key CB, Shook JE, Kimball KT, Ward MA. Racial distribution of pediatric cardiopulmonary arrest cases. Acad Emerg Med May 1996;3:431-432. To be presented at the Annual meeting of the Society for Academic Emergency Medicine, May 6, 1996 in Denver, Colorado. Sirbaugh PE, Shook JE, Myers JH, Bickford JR, Pepe PE. The effect of therapeutic interventions on the outcome of out-of-hospital pediatric cardiopulmonary arrest. Acad Emerg Med May 1996;3:454. Presented at the Annual meeting of the Society for Academic Emergency Medicine, May 6, 1996 in Denver, Colorado. Wall MJ, Liscum K, Key C, Stephens C, Persse D, Pepe PE, Mattox KL. Prehospital cardiopulmonary resuscitation of the trauma patient. Presented at the Southwestern Surgical Congress Annual Meeting, April 1997. Key CB, Persse DE, Pepe PE, Cordi HP, Ginger VF, Kimball KT. Automated Alarms for Urban 9-1-1 EMS Response: Evaluating the feasibility of sending first responders without ambulances. Acad Emerg Med 1997; 4:414-415. Presented at the Annual meeting of the Society for Academic Emergency Medicine, May 20, 1997 in Washington, D.C. Key CB, Persse DE, Pepe PE, Cordi HP, Ginger VF, Kimball KT. Safety of First Responder Only Utilization for Motor Vehicle Incidents When the 9-1-1 Caller is Unable to Answer Standard Medical Priority Dispatch Questions. Acad Emerg Med 1997; 4:414. Presented at the Annual meeting of the Society for Academic Emergency Medicine, May 20, 1997 in Washington, D.C. Myers JH, Sirbaugh PE, McCurren RH, Shook JE, Persse DE, Pepe PE. Consideration of the paramedics’ perspective in determining policies for on-scene termination of resuscitation efforts. Acad Emerg Med 1997; 4:496. Presented at the 1997 Meeting of the Society for Academic Emergency Medicine, May 20, 1997, Washington D.C.

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Pepe PE, Zachariah BS. Automated defibrillation by laypersons: the success of an ABCD training curriculum. Proceedings of the American Heart Association Public Access Defibrillation II Conference, April 18, 1997, Crystal City, Virginia. Cordi HP, Persse DE, Key CB, Pepe PE. Ability of a Caller to 9-1-1 to correctly identify a person as Dead on Scene. Prehosp Emerg Care 1997; 1: 173. Presented at the 1997 Annual Meeting of the National Association of EMS Physicians, July 8, 1997, in Lake Tahoe, CA. Persse DE, Key CB, Pepe PE. Effect on workforce of utilizing non-transport first responders instead of ambulances to respond to EMS requests with no information. Prehosp Emerg Care 1997; 1:171. Presented at the 1997 Annual Meeting of the National Association of EMS Physicians, July 8, 1997, in Lake Tahoe, CA. Pepe PE. Prehospital Trauma Interventions: Scoop and Run. J Emerg Med, March 1998;16:370. Presented at the 7th International Conference on Emergency Medicine, March 26, 1998, Vancouver, Canada. Ghaemmaghami CA, Harchelroad F, Elson J, Pepe PE, Locasto D, Evans T. Feasibility and utility of hand-held blood analyzers used in modifying patient management during cardiac resuscitation. Acad Emerg Med 1998;5:398. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 17, 1998 in Chicago, IL. Persse DE, Baldwin JB, Pepe PE, Kimball KT. The prolonged effect of a municipal gun responsibility ordinance on firearm injury deaths in minors. Acad Emerg Med 1998;5:523. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 19, 1998 in Chicago, IL. Key CB, Persse DE, Pepe PE, Bradley R, Meskill-Labay D. Urban EMS response to automated 9-1-1 alarms: a prospective evaluation of the safety and operational advantages of dispatching rapidly-responding first responder crews without ambulances. Acad Emerg Med 1998;5:441-442. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 18, 1998 in Chicago, IL. Larabee TM, Tamblyn ER, DeBehnke DJ, Kuhn EM, Brady WJ, Pepe PE, Aufderheide TP. Asystolic, unwitnessed out-of-hospital cardiac arrest and no bystander CPR as a criterion for waiving resuscitation efforts. Acad Emerg Med 1999;6:446. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 20, 1999, Boston, MA. Pepe PE, Scheatzle MD, Forjuoh SN, Dearwater SR, Aronson AA. Would more people perform basic CPR if mouth-to-mouth ventilation was considered optional? Acad Emerg Med 1999;6:430. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 21, 1999, Boston, MA. Scheatzle MD, Dearwater SR, Pepe PE, Forjuoh SN, Aronson AA. Motivation and perceived barriers to participating in CPR training identified by a cross-sectional phone survey. Acad Emerg Med 1999;6 :429. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 21, 1999, Boston, MA. Key, CB, Calderon D, Persse DE, Pepe PE, Kimball KT. Prospective evaluation of the effects of only dispatching fire apparatus first responders to automobile 9-1-1 alarms and motor vehicle incidents lacking definitive caller information. Acad Emerg Med 2000; 7:476. Presented at the Society for Academic Emergency Medicine Annual Meeting May 22, 2000, San Francisco, CA. Wigginton JG, Bedolla JP, Pepe PE, DeTamble LA, Atkins JM. Population-based, prospective study of gender-related difference in survival following out-of-hospital cardiac arrest. Acad Emerg Med 2000; 7:437. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 22, 2000, San Francisco, CA.

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Pepe PE, Mulligan-Smith D, Branche CM. A seven-year, statewide study of the epidemiology of pediatric drowning deaths. Acad Emerg Med 2002; 9:488-489. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 21, 2002, St. Louis, MO. Hall WL, Marcucci JF, Pepe PE, DeTamble LA, Wigginton JG. Paramedic Reluctance to Terminate Resuscitation Efforts for Out-of-Hospital Cardiac Arrest Patients: Potential Factors Affecting Paramedics’ Comfort Level with a Proposed New Field Termination Protocol. Prehosp Emerg Care. 2002; 6;151-152. Presented at the Annual Meeting of the National Association of EMS Physicians, January 10, 2002, Tucson, Arizona. Pepe PE, Wigginton JG, Mann DM, Persse DE, Sirbaugh PE, Berg RA. Prospective decade-long population-based study of pediatric drowning-related incidents. Acad Emerg Med 2002; 9:516-517. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 22, 2002, St. Louis, MO. Pepe PE, Mulligan-Smith D, Branche CM. A seven-year, statewide study of the epidemiology of pediatric drowning deaths. Presented at the 9th International Conference on Emergency Medicine, June 21, 2002, Edinburgh, Scotland.

Pepe PE, Raedler C, Lurie KG, Wigginton JG. Emergency ventilatory management in severe hemorrhagic states: elemental or detrimental? J Trauma 2002;53:(6) 190 June 2002. Presented at the Annual Meeting of the American Association for the Surgery of Trauma, Sept. 27, 2002, Orlando, FL. Lurie KG, Pepe PE. Use of an inspiratory impedance threshold valve for the rapid treatment of severe hemorrhagic states. J Trauma 2002;53:190. Presented at the Annual Meeting of the American Association for the Surgery of Trauma, September 27, 2002, Orlando, FL. Raedler C, Lurie KG, Wigginton JG, McKnite J, Zielinsky T, Voelckel WG, Pepe PE. Hypoventilation improves minute coronary perfusion pressure in an animal model of severe controlled hemorrhagic shock. Circulation 106(19) Supplement. November 5, 2002. II-497. Presented at the 2002 Annual Scientific Sessions of the American Heart Association, Chicago, IL. November 19, 2002. AHA. Bar-Joseph G, Abramson NS, Kelsey SF, et al, for the Brain Resuscitation Clinical Trial III Study Group (incl Pepe PE). Sodium bicarbonate during cardiopulmonary resuscitation enhances restoration of spontaneous circulation. Circulation (supplement) 2002; 107: 104. Presented at the 2002 Annual Scientific Sessions of the American Heart Association, Chicago, IL. November 19, 2002. AHA. Pepe PE. A government emergency medical security services (GEMSS) fellowship. Society of Academic Emergency Medicine (SAEM) Western Region. Presented at Scottsdale, AZ, April 5, 2003. Fowler RL, Pepe PE. Non-transport of EMS patients by paramedics: Employing audit mechanisms to identify individual paramedic performance. Society of Academic Emergency Medicine (SAEM) Western Region. Presented at Scottsdale, AZ, April 5, 2003. Pepe, PE. The Advanced Disaster Life Support (ADLS) Course. Proceedings of Academic Emergency Medicine (SAEM) Western Region. Presented at Scottsdale, AZ, April 5, 2003. Pepe PE. The Basic and Advances Disaster Life Support Courses. Ann Emerg Med 2003;42(4) S108. Presented at Annual Meeting of the American College of Emergency Physicians, Oct. 13, 2003, Boston, MA. Pepe PE, Schwartz RB, Dallas C, Lillibridge S, Swienton R, Coule P, James J. The National Advanced Disaster Life Support (ADLS) course. Circulation (supplement) Oct 28, 2003;108(17): IV-1033. Presented at the annual scientific sessions of the American Heart Association, Nov. 8, 2003, Orlando, FL.

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Pepe PE, Raedler C, Wigginton JG, Idris A, Lurie KG. Confounding hemodynamic effects of ventilation in hemorrhagic conditions. Circulation (supplement) October 28, 2003;108(17): 581-582. Presented at the annual scientific sessions of the American Heart Association, November 11, 2003, Orlando, FL. Pepe PE, Raedler C, Wigginton JG, Idris A, Lurie KG. Outcome Following Major Hemorrhage: The confounding variable of ventilatory management. Prehosp Emerg Care Jan 2004 8:85. Presented at the annual meeting of the National Association of Emergency Medical Services Physicians, January 10, 2004, Tucson, AZ. Wigginton J, Pepe PE, Idris A, Persse D, Berg R. Pivotal role of bystander cardiopulmonary resuscitation in pediatric drowning incidents. Crit Care 2004, 8(Supp 1):P288. Presented at Annual Meeting of 24th International Symposium on Intensive Care and Emergency Medicine, April 2004. Wigginton J, Pepe PE, Idris A, Raedler C, Lurie K. Confounding hemodynamic effects of assisted ventilation in hemorrhagic states. Crit Care 2004, 8(Suppl1):P46. Presented at Annual Meeting of 24th International Symposium on Intensive Care and Emergency Medicine, April 2004. Roppolo LP, Westfall A, Pepe PE, Idris AH. Assessment of agonal breathing improves detection of cardiac arrest. Circulation October 26, 2004;110 (17) supplement III: III-456 (abstract). Presented at the Annual Scientific Sessions of the American Heart Association, Nov 8, 2004 in New Orleans, LA. Fowler RL, Pepe PE, Melville DM, Eastman Al, Larkin GL. Non-transport of EMS patients: Identification of individual paramedic crew behavior through system-wide automated audit mechanisms. Prehosp Emerg Care 2005; 9:129. Presented at the annual meeting of the National Association of Emergency Medical Services Physicians, January 14, 2005, Naples FL. Roppolo L, Pepe P, Westfall A, Idris A, Wigginton J. Identification of agonal breathing by dispatchers to improve the detection and treatment of cardiac arrest. Crit Care March 2005; 9 (supplement 1):127. Presented at the 25th International Congress on Intensive Care and Emergency Medicine, March 22, 2005, Brussels, Belgium. Roppolo L, Pepe P, Martinez J. A prospective study comparing standard laryngoscopy with the trachview videoscope system for orotracheal intubation. Crit Care March 2005; 9 (supplement 1):51. Presented at the 25th International Congress on Intensive Care and Emergency Medicine, March 22, 2005, Brussels, Belgium.

Pepe PE, Roppolo LP, Westfall A and Idris AH. Assessment of agonal breathing improves the

detection of cardiac arrest. Proceedings of the VIII Wolf Creek Conference on Resuscitation.

Presented at the VIII Wolf Creek Conference, June 12, 2005, Palm Springs, CA

Wigginton JG, Pepe PE, Idris AH, and Fowler RL. Potential pharmaco-biological and hormonal

effects on resuscitation. Proceedings of the VIII Wolf Creek Conference on Resuscitation.

Presented at the VIII Wolf Creek Conference, June 12, 2005, Palm Springs, CA

Idris AH, Roppolo LP, Pepe PE. A thirty minute CPR course. Proceedings of Wolf Creek VII

meeting on Resuscitation. Presented at the VII Wolf Creek Conference, June 12, 2005, Palm

Springs, CA

Roppolo LP, Ohman K, Pepe PE, Idris AH. The effectiveness of a short cardiopulmonary

resuscitation course for laypersons. Circulation October 25 2005;112 (supplement II):325-326

(abstract 1627). Presented at the Annual Meeting of the American Heart Association, November

13, 2005, Dallas TX.

Idris AH, Roppolo LP, Ohman K, Pepe PE. A five minute training program for automated external

defibrillator use is more effective than a 4-hour course. Circulation October 25 2005;112 (supplement

II):326 (abstract 1628). Presented at the Annual Meeting of the American Heart Association,

November 13, 2005, Dallas TX.

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Wigginton JG, Pepe PE and Idris AH. Potential pharmaco-biological and hormonal effects on resuscitation. Crit Care March 2006; 10 (supplement 1):101. Presented at the 26th International Congress on Intensive Care and Emergency Medicine, March 22, 2006, Brussels, Belgium. Wigginton JG, Pepe PE and Idris AH. Acad Emerg Med May 2006;13 (supplement 1):S174. Potential pharmacobiological and hormonal effects on resuscitation. Presented at the Annual Meeting of the Society for Academic Emergency Medicine, May 21, 2006, San Francisco. Idris AH, Luber S, Minei JP, Madden C, Brown RJ, Pepe PE. Lower ventilation rates improve tissue oxygenation and perfusion during hemorrhagic shock. Circulation October 31 2006; 114 (Supplement II);II-1209-1210 (Abstract 109). Presented at the Annual Meeting of the American Heart Association, November 11, 2006, Dallas TX.

**Winner of Best Abstract Award for Trauma at the Resuscitation Science Symposium**. Eastman AL, Metzger JC, Benitez Fl, Decker J, Rinnert KJ, Pepe PE. Conductive electrical weapons: A prospective, population-based study of the safety of the application by law enforcement. J Trauma 2007. Presented at the 37th annual meeting of the Western Trauma Association, Steamboat Springs, Colorado, Friday, March 2, 2007. Fowler RL, Pepe PE. Failure of respiratory rate to predict measured capnography levels in prehospital advanced life support patients. Proceedings of the Mediterranean Emergency Medical Conference IV, European Society of Emergency Medicine, Sorrento, Italy, September 2007. Presented at the 2007 Joint Mediterranean Congress of the European Society for Emergency Medicine and the American Academy of Emergency Medicine, September 19, 2007. Sorrento, Italy. Harmann CJ, Larkin GL, Burkhalter L, Brown B, Schwan C, George V, Pepe PE, Treichler B. Differences in computer-prompted self-report and physician-elicited responses in screening of emergency department patients for substance use and abuse. Ann Emerg Med September 2007 50;S43. Presented at the 2007 Scientific Assembly of the American College of Emergency Physicians, October 8, 2007, Seattle, WA. Metzger J, Maher P, Wainscott M, Pepe PE, Delaney K. Injuries sustained by patients with behavioral disturbances brought to the emergency department in police custody. Crit Care 2008;12 (Suppl 2):137-138. Presented at the 28th Annual International Symposium on Intensive Care and Emergency Medicine, March 18, 2008, Brussels, Belgium. Metzger J, Maher P, Wainscott M, Pepe PE, Delaney K. Patterns of medical illness and injuries in emotionally disturbed patients brought to an emergency department in police custody. Crit Care 2008;12 (Suppl 2):138. Presented at the 28th Annual International Symposium on Intensive Care and Emergency Medicine, March 18, 2008, Brussels, Belgium. Luber S, De Give D, Roppolo L, Todd C, Sharda R, Patyrak S, Byrne D, Pepe P. Reliabilty of point-of-care hemoglobin testing in the emergency department. Ann Emerg Med 2008;51:497 (abstract 85). Presented at the International Congress on Emergency Medicine, April 3, 2008, in San Francisco, CA. Pepe PE, Yannopoulos D, Matsuura T, Alexander C, McKnite SH, Wigginton JG, Idris AH, Lurie KG. The physiological and hemodynamic effects of varying tidal volumes and respiratory rates in hemorrhagic conditions. Proceedings of the 2008 Annual Meeting of the American Association for the Surgery of Trauma (AAST). Presented September 25, 2008 in Wailea, HI. Black A, Muniz J, Benitez FL, Burkhalter L, Isaacs SM, Luber SD, Pepe PE, Velez LI. Baseline carboxyhemoglobin levels in firefighters using the Masimo Rainbow SET Rad-57 Pulse CO-Oximeter Annals Emerg Med 2009;54:S77-S78. Idris AH, Luber S, Minei JP, Madden C, Brown RJ, Pepe PE. Lower ventilation rates improve tissue oxygenation and perfusion during hemorrhagic shock. Proceedings of the 2009 Wolf Creek X Meeting, Rancho Mirage, CA. Presented June 19, 2009 in Rancho Mirage, CA.

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Wigginton JG, Saner K, Schug K, Simpkins J, Gatson J, Pepe PE, Madden C, Minei J, Idris A.Sex steroid level alterations in the blood and cerebrospinal fluid following severe traumatic brain injury. Circulation November 2009;120:S1441. Presented at the Annual Scientific. Presented at the Annual Scientific Sessions of the American Heart Association (AHA), November 11, 2009, Orlando, FL

**Cited as a “Best of the Best” Presentation **

Wigginton JG, Gatson, JW, Maas DL, Simpkins J, Idris A, Minei J, Pepe P. Estrogen treatment following severe burn injury reduces brain inflammation and apoptotic signaling. Crit Care Med December 2009;37(12):A409. Presented at the 39th Critical Care Congress. Society of Critical Care Medicine, January 12, 2010, Miami Beach, FL. Gatson JW, Zang Q, Maass DL, Minei JP, Idris AH, Pepe PE, Wigginton JG. Estrogen decreases inflammation and apoptotic signaling in the heart following severe burn injury. Estrogen decreases inflammation and apoptotic signaling in the heart following severe burn injury. Crit Care 2010;14(Supp1):S194 (P584; doi 10.1186/cc8816). Presented at the 30th Annual Meeting of the International Symposium on Intensive Care and Emergency Medicine (ISICEM), March 9, 2010, Brussels, Belgium.

***Selected as a Finalist (top ten of 600 papers) for the Symposium’s Best Paper Award***.

Gatson JW, Idris AH, Pepe PE, Minei JP, Wigginton JG. Estrogen decreases inflammation and apoptotic signaling in the heart following severe burn injury. Measurement of neuronal specific enolase as a predictor of outcome in patients suffering from severe traumatic brain injury. Crit Care 2010; 14(Supp1):S102 (P301; doi 10.1186/cc8533). Presented at the 30th Annual Meeting of the International Symposium on Intensive Care and Emergency Medicine (ISICEM), March 9, 2010, Brussels, Belgium.

***Selected as a Finalist (top ten of 600 papers) for the Symposium’s Best Paper Award***.

Wigginton J, Gatson J, Simpkins J, Pepe P, Idris A, Minei J. Post-burn 17β-estradiol administration significantly decreases the early pulmonary inflammatory response, and improves lung function following experimental severe burn injury. Inflammation Research March 2010; 59 (suppl 1):S134 (A345). Presented (oral presentation) at the 8th World Congress on Trauma, Shock, Inflammation and Sepsis - TSIS 2010, Munich, Germany, March 13, 2010. Wigginton J, Gatson J, Simpkins J, Pepe P, Idris A, Minei J. Increased aromatase expression may be responsible for increased estrogen levels in the brain following severe traumatic brain injury. Inflammation Research March 2010; 59(suppl 1):S138-139 (A356). Oral presentation) at the 8th World Congress on Trauma, Shock, Inflammation and Sepsis - TSIS Munich, Germany, March 13, 2010. Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Rea TD, Callaway C, Pepe PE, Schmicker RH, Vaillancourt C, Chugh SS. Socioeconomic Disparities and Burden of Sudden Cardiac Arrest in Metropolitan Areas: A USA-Canada Comparative Analysis Circulation November 23, 2010;122(21):A18723. Presented at the Annual Scientific Sessions of the American Heart Association, Chicago, IL, November 15, 2010. Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux B, Kudenchuk PJ, Christenson J, Pepe PE, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clement CM, Craig A, Van Ottingham L, Schmidt TA, Wang H, Weisfeldt ML, Ornato JP, Sopko G, and the Resuscitation Outcomes Consortium (ROC Investigators: The Resuscitation Outcomes Consortium (ROC) PRIMED Impedance Threshold Device (ITD) cardiac arrest trial: A prospective, randomized, double-blind, controlled clinical trial. Circulation November 23, 2010; 122(21):S2225. Presented as an oral abstract at Resuscitation Science Symposium (ReSS), American Heart Association 2010 Scientific Sessions, Chicago, Illinois, November 13, 2010.

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Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux BG, Pepe PE, Kudenchuk PJ, Christenson J, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clemen CM, Craig A, Van Ottingham L, Schmidt TA, Wang HE, Weisfeldt ML, Ornato JP, Sopko G and the Resuscitation Outcomes Consortium (ROC) Investigators. The Resuscitation Outcomes Consortium (ROC) PRIMED impedance threshold device (ITD) cardiac arrest trial: a prospective, randomized, double-blind, controlled clinical trial. Prehosp Emerg Care Jan 2011. Presented as an oral presentation at the 2011 National Association of EMS Physicians Annual Meeting in Bonita Springs, FL. January 14, 2011. Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux BG, Kudenchuk PJ, Christenson J, Pepe PE, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clement CM, Craig A, Van Ottingham L, Schmidt TA, Wang HE, Weisfeldt ML, Ornato JP, Sopko G and the Resuscitation Outcomes Consortium (ROC) Investigators. The Resuscitation Outcomes Consortium (ROC) PRIMED impedance threshold device (ITD) cardiac arrest trial: a prospective, randomized, double-blind, controlled clinical trial. Prehosp Emerg Care Jan-Mar 2011;15(1):104. Presented as an oral presentation at the 2011 National Association of EMS Physicians Annual Meeting in Bonita Springs, FL. January 14, 2011. http://informahealthcare.com/action/doSearch?type=simple&filter=multiple&searchText=PRIMED+impedance+threshold+device+&categoryId=40053927&history

Wigginton JG, Gatson JW, Maass DL, Simpkins JW, Barber R, Zang Q, Huebinger R, Wigginton KG, Pepe PE, Minei JP, AbdelFattah KR, Idris AH. Single-dose post-burn estrogen significantly preserves lung function and architecture at seven days following severe burn injury. Shock June 2011 35(7) Suppl 1: pgs. 1-65 (P166). Presented at the 34th Annual North American Shock Society Meeting, June 13, 2011 in Richmond, VA

Wigginton JG, Pepe PE, Simpkins JW, Gaston JW, Wigginton KG, AbdelFattah KR, Minei JP, Maass DL. Early, single-dose, post-burn estrogen significantly decreases burned skin and systemic inflammatory response for 7 days following severe burn injury. Presented (oral) at the annual meeting of the American Association for the Surgery of Trauma (AAST), in Chicago, IL. September 16, 2011 (Session 8a, paper 23), listed on the AAST website: http://aast.org/asset.axd?id=d6a53da8-1190-4f34-8d2a-fc8df33ddc18&t=634503810881600000 Wigginton JG, Pepe PE, AbdelFattah KR, Maass DL, Idris AH, Minei JP, Gatson JW, Simpkins JW. Indirect brain injury resulting from severe burns results in estrogen reversible elevations of markers of Alzheimer's Disease. Circulation 124:A5. Presented at the Scientific Sessions of the American Heart Association (AHA) Resuscitation Science Symposium (ReSS), Nov. 11, 2011, Orlando, FL

**** Selected for “Best of the Best” Oral Presentation*** Idris AH, Guffey D, Pepe PE, Daya MR, Davis DP, Stiell I, Menegazzi JJ, Callaway CW, Christenson J, Gray R, Boyce D, Sopko G, Lin S, Sheehan K, Aufderheide T the ROC Investigators. The relationship of chest compression rate and survival during out-of-hospital cardiopulmonary arrest at Resuscitation Outcomes Consortium (ROC) sites.Circulation 2011;124 (Suppl 21): 289. Oral presentation at the 2011 Scientific Sessions of the American Heart Association, Orlando FL, November 16, 2011. Wigginton JG, Pepe PE, Simpkins JW. Gatson JW, Wigginton KG, Kareem KR, Minei JP, Maass D. Early administration of parenteral estrogen suppresses the deleterious local and systemic inflammatory response in severe burns. Crit Care 2012;16 (Suppl1):165. Abstract P465 presented at the annual International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 20, 2012.

***Selected as a Finalist (top ten of 800 papers) for the Symposium’s Best Paper Award***.

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Wigginton J, Pepe P, AbdelFattah KR, Maass D, Gaston J, Minei J, Wigginton KJ, Simpkins J. Indirect brain injury resulting from severe remote burns results in estrogen-reversible elevations of markers of Alzheimer’s Disease (AD) over the first 45 days post-burn. Shock 2012; 37 (Suppl 1):16. Presented (oral) at the annual meeting of the International Federation of Shock Societies Annual Conference on Shock, Miami, FL, June 10, 2012. doi: 10.1097/SHK.0b013e3182597adb

Pepe PE, Wigginton JG, Abdel Fattah, KR, Wigginton KG, Simpkins JW. Single-dose rapid parenteral estrogen to suppress detrimental inflammatory response in severe burns. Presented (oral) at the annual meeting of the International Congress on Emergency Medicine, Dublin, Ireland, June 28, 2012. Track 3: Resuscitation and Trauma: LO0128. http://www.icem2012.org/home/thursday.214.html Wigginton J, Pepe P, Gaston JW, Simpkins J, Maass D, AbdelFattah KR, Idris A, Warren V, Minei JP. Indirect brain injury from severe remote burns results in estrogen-induced increases in brain levels of sonic hedgehog (SHH), a signaling protein controlling division of adult stem cells. Poster 37 presented at the annual meeting of the American Association for the Surgery of Trauma (AAST), in Poipu, Kauai. Hawaii, September 12, 2012. Listed on the AAST website: http://aast.org/asset.axd?id=d1acc6e0-32ba-4a8f-

a10bfc98deaa56ff&t=634817588192330000 Wigginton J, Warren V, AbdelFattah KR, Gaston JW, Pepe PE, Simpkins JW, Minei JP Maass DL, Idris A. The feasibility and methods of an exception from informed consent pilot study of estrogen in trauma patients in the emergency department (ED). Circulation 2012;126 (Suppl 21):A10. Presented at the 2012 Scientific Sessions of the American Heart Association, Los Angeles, CA, Nov. 3, 2012. Idris AH, Guffey D, Aufderheide TP, Brown SP, Pepe PE, Daya MR, Davis DP, Stiell IG, Menegazzi JJ, Callaway CW, Christenson J, Gray R, , Brooks S, Larsen J, Lin S, Sheehan K, Kudenchuk PJ Sopko G, Nichol G and the ROC Investigators. The interaction of chest compression rates with the impedance threshold device (ITD): association with survival following out-of-hospital cardiac arrest. Circulation 2012;126:2776-2799; LBRS-352. Presented at the 2012 Scientific Sessions of the American Heart Association, Los Angeles, CA, November 4, 2012. doi: 10.1161/CIR.0b013e318278c90d http://conferencecast.com/AHA/common/presentations.aspx?ConfID=8&TrackID=21&SessionID=726

** “Best Original Resuscitation Science Poster” Session Idris AH, Guffey D, Pepe PE, Brown SP, Aufderheide TP, Brooks S. Callaway CW, Christenson J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K Sopko G, Stiell IG, Nichol G and the ROC Investigators. Chest compression rates between 100 and 120 per minute are independently associated with increased adult survival following out-of-hospital cardiac arrest. Circulation 2012;126 (Suppl 21):A16132. Presented at the Annual Scientific Sessions of the American Heart Association, Los Angeles, CA, November 6, 2012.

Idris AH, Guffey D, Pepe PE, Brown SP, Aufderheide TP, Brooks S. Callaway CW, Christopher J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K Sopko G, Stiell IG, Nichol G and the ROC Investigators. The interaction of chest compression rates with the impedance threshold device (ITD): association with survival following out-of-hospital cardiac arrest. Prehosp Emerg Care 2013;17(1):112. Poster 36 presented at the 2013 Annual Meeting of the National Association of EMS Physicians, Bonita Springs, FL January 10, 2013. Idris AH, Guffey D, Aufderheide TP, Brown SP, Pepe PE, Daya MR, Davis DP, Stiell IG, Menegazzi J, Callaway CW, Christenson J, Gray R, Brooks S, Larsen J, Lin S, Sheehan K, Kudenchuk PJ, Sopko G, Nichol G and the ROC Investigators. Chest compression rates between 100 and 120 are associated with increaed survival. Prehosp Emerg Care 2013;17(1):112. Poster 38 presented at the 2013 Annual Meeting of the National Association of EMS Physicians, Bonita Springs, FL Jan 10, 2013.

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Wigginton JG, Simpkins JW. Pepe PE, Maass D, Warren V, Gatson JW, Wigginton KG, Minei JP, Wolf S, Idris A. Early single-dose, post-burn estrogen significantly decreases lung inflammation and improves lung function 45 days following severe burn injury. Crit Care Med 2012; 40(12 Suppl 1): P202. Oral presentation at the annual meeting of the Society of Critical Care Medicine, San Juan, Puerto Rico, January 18, 2013. Pepe PE, Wigginton JG, Gatson JW, Simpkins J, Maass D, AbdelFattah K, Idris AH, Warren V, Minei JP. Single dose estrogen infusion can amplify brain levels of sonic hedgehog (SHH), a signal protein for neuro stem cells and repair following the indirect brain injury resulting after severe torso burns. Critical Care 2013. Abstract P287 presented at the 2013 International Symposium in Intensive Care and Emergency Medicine, Brussels, Belgium, March 19, 2013.

*** Finalist for Best Paper Award at the Symposium (Top 10 of 800 papers) **** Wigginton JG, Pepe PE, Warren V, AbdelFattah K, Gatson JW, Simpkins J, Minei JP. Maass D, Idris AH.The feasibility and experience with using exception from informed consent in a pilot study of immediate estrogen infusion for hypotensive trauma patients. Critical Care 2013. Abstract P288 presented at the 2013 International Symposium in Intensive Care and Emergency Medicine, Brussels, Belgium, March 19, 2013. Wigginton JG, Pepe PE, Gatson JW, Idris AH. Early administration of a single dose of parenteral estrogen decreases inflammation in the heart for 45 days after severe burns. Critical Care 2013. Abstract P289 presented at the 2013 International Symposium in Intensive Care and Emergency Medicine, Brussels, Belgium, March 19, 2013. Warren V, Maass DL, Idris AH, Pepe PE, Gatson JW, Ma L, Zang QS, AbdelFattah K, Minei JP, Wolf S, Wigginton JG. Single-dose, post-burn estrogen significantly decreases apoptosis at 7 days and pro-inflammatory cytokines for 45 days in the spleen following severe burns. Circulation 2013. Presented as a lead-off oral presentation (Best Trauma abstract) at the annual Scientific Sessions of the American Heart Association, Resuscitation Science Symposium, in Dallas, TX, November 16, 2013.

****Selected as the “Best Trauma Paper” for the Resuscitation Science Symposium ***** Wigginton JG, AbdelFattah KR Gatson JW, Pepe PE, Emerson S, Simpkins JW, Bulger E, Foreman M, Hoyt D, Kerby J, Maass DL, Madden C, May S, Minei JP, Powell J, Ramsay MA, Roberts J, Saner K, Schug K, Egan D, Sopko G, Idris AH. A feasibility and safety pilot clinical trial of single-dose, intravenous estrogen for resuscitation of traumatic hemorrhagic shock - the RESCUE shock study (abstract). Circulation 2014;130;2105-2126. doi: 10.1161/01.cir.0000457464.79076.2c Late-breaking clinical trials #32 presented at the American Heart Association Scientific Sessions, Chicago IL, November 15, 2014. Wigginton JG, AbdelFattah K, Pepe P, Emerson S, Gatson J, Simpkins J, Bulger E, Foreman M, Hoyt D, Kerby J, Maass D, Madden C, May S, Minei J, Powell J, Ramsay MA, Roberts J, Saner K, Schug K, Egan D, Sopko G, Warren V, Idris AH. A pilot clinical trial of single-dose, intravenous estrogen for resuscitation of severe traumatic brain injury (TBI): the RESCUE TBI Study (abstract). Circulation 2014;130;2105-2126. doi: 10.1161/01.cir.0000457464.79076.2c Late-breaking clinical trials #13 – oral presentation at the American Heart Association Scientific Sessions, Chicago IL, November 16, 2014. Pepe PE, Isaacs SM, Fowler RL, Miller R and Carlo JT. Evaluation of actions -- and subsequent reactions -- of an emergency medical services (EMS) system during the first Ebola outbreak outside of Africa. Brit Med J 2015. Presented at the 2015 International Forum on Quality and Safety in Health Care, International Improvement Science and Research Session, 22 April 2015, 1530-1630 hours, London, UK. Pepe PE, Scheppke KA, Antevy PM, Coyle C, Millstone D, Prusansky C, Moore JC. How would use of flow-focused adjuncts, passive ventilation and head-up CPR affect all-rhythm cardiac arrest resuscitation rates in a large, complex EMS system? [abstract] Circulation 2016;134 Supplement 1: A15255. Presented by Dr. Pepe at the Annual Scientific Sessions of the American Heart Association, November 13, 2016, New Orleans, LA.

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Duval S, Pepe PE, Goodloe JM, Sugiyama A, Yannopoulos D. The CPR “sweeter spot”: a target combination of optimal chest compression rate and depth to achieve survival with favorable neurological function after out of hospital cardiac arrest. [abstract] Circulation 2016;134 Supplement 1: A19230. Presented by Dr. Pepe at the Annual Scientific Sessions of the American Heart Association, November 14, 2016, New Orleans, LA.

Pepe PE, Scheppke KA, Antevy PM, Coyle C, Millstone D, Moore JC. Impact of head-up/torso chest compressions and flow-oriented CPR adjuncts on survival. Crit Care Med December 2016;44(Supplement):284. Presented by Dr. Pepe at the Annual Critical Congress of the Society of Critical Care Medicine, January 22, 2017, Honolulu, HI.

**** Featured as Snapshot Award Presentation ****

Antevy PM, Goldman HB, Pepe PE. Mobile integrated healthcare in an acutely ill Medicare cohort.

Prehosp Emerg Care 2017;21;130. Presented by Dr. Antevy at the Annual Meeting of the National Association of EMS Physicians, January 26, 2017, New Orleans, LA. Scheppke KA, Pepe PE, Antevy PM, Coyle C, Millstone D, Moore JC. Feasibility and safety of a head/torso-Up chest compression technique in cardiopulmonary resuscitation. Acad Emerg Med Acad Emerg Med 2017;24:S166. E-Poster presented by Dr. Scheppke at the Southeast Regional Meeting of the Society for Academic Emergency Medicine, February 10, 2017, Jacksonville, FL.

*** Runner-Up for Best Paper (E-Poster) Award Presentation **** Pepe PE. Event medicine: an evolving academic subspecialty in emergency medicine. Prehosp Disast

Med April 2017;32: S130. Oral presentation by Dr. Paul Pepe at the World Association for Emergency

and Disaster Medicine, Thursday April 27, 2017, Toronto, ON, Canada.

DOI: https://doi.org/10.1017/S1049023X17003636. Published online: 20 April 2017, p. S130

Scheppke KA, Pepe PE, Antevy PM, Coyle C, Millstone D, Moore JC. The Survival impact of exploring novel resuscitation concepts for communities with complex emergency medical services systems. Presented by Dr. Scheppke at the International Forum on Quality and Safety in Healthcare, Frodau April 28, 2017, London, UK Pepe PE, Scheppke KA, Antevy PM, Coyle C, Millstone D, Moore JC. Feasibility and safety of a head/torso-Up chest compression technique in cardiopulmonary resuscitation. Acad Emerg Med 2017;24:S166. Oral presentation by Dr. Pepe at the Annual National Meeting of the Society for Academic Emergency Medicine (SAEM), Friday, May 19, 2017, Orlando, FL doi:10.1111/acem.13203 Pepe PE, Debaty G, Yannopoulos D, Moore JC. Delineating the value-added inclusion of the impedance threshold device during head-up CPR. Ann Emerg Med 2017;70: (in press). To be presented by Dr. Pepe at the Annual Scientific Assembly of the American College of Emergency Physicians, October 31, 2017, Washington, D.C. Banerjee PR, Pepe PE, Singh A, Ganti L. Early transport versus on-scene management of pediatric out-of-hospital cardiac arrest. Ann Emerg Med 2017;70:(in press). To be presented by Drs. Pepe and Banerjee at the Annual Scientific Assembly of the American College of Emergency Physicians, Monday, October 30, 2017, Washington, D.C. Banerjee PR, Pepe PE, Singh A, Ganti L. Early predictors of a good outcome after pediatric cardiac arrest. Ann Emerg Med 2017;70: (in press). To be presented by Drs. Banerjee, Ganti and Pepe at the 2017 Annual Scientific Assembly of the American College of Emergency Physicians, Tuesday, October 31, 2017, Washington, D.C. Banerjee PR, Pepe PE, Singh A, Ganti L. Early outcome determinants in pediatric out-of-hospital cardiac arrests post-2010. To be presented by Dr. Ganti at the European Society for Emergency Medicine (EuSEM) in Athens, Greece on Sunday, September 24, 2017 in Athens, Greece.

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Pepe PE, Banerjee PR, Singh A, Ganti L. Modified management strategies to improve survival chances following pediatric out-of-hospital cardiac arrest. Circulation 2017;136 (in press). To be presented by Dr. Pepe at the annual Scientific Sessions of the American Heart Association Sunday, November 12, 2017, Anaheim, CA. Abstracts Recently Submitted: Mueller-Kronast N, Marulaunda-Londono E, Wang K, et al (12 other authors including Pepe PE) for the Florida-Puerto Rico CReSD Investigators (Collaboration to Reduce Stroke Disparities). Impact of EMS directly transporting patients with suspected acute ischemic stroke to comprehensive stroke centers in South Florida Submitted to the 2018 International Stroke Conference, Los Angeles, CA January 24, 2018 Banerjee PR, Pepe PE, Singh A, Ganti L. Factors associated with a good outcome following pediatric out-of-hospital cardiac arrest in the post-2010 resuscitation guidelines era. If accepted, Prehosp Emerg Care 2018;22. Submitted to the Annual Meeting of the National Association of EMS Physicians (NAEMSP), January 2018, San Diego, CA. Pepe PE, Banerjee PR, Singh A, Ganti L. Effecting neurologically-intact survival for children with out-of-hospital cardiac arrest. If accepted, Prehosp Emerg Care 2018;22 (to be in press). Submitted to the Annual Meeting of the National Association of EMS Physicians (NAEMSP), Jan. 2018, San Diego, CA. Pepe PE, Scheppke KA, Antevy PM, Millstone D, Coyle C, Prusansky C, Garay S, Moore JC. Confirming the safety and feasibility of a bundled resuscitation technique involving a head-up/torso-up mechanical chest compression technique for cardiopulmonary resuscitation. If accepted, Prehosp Emerg Care 2018;22 (to be in press). Submitted to the Annual Meeting of the National Association of EMS Physicians (NAEMSP), January 2018, San Diego, CA. Roach JP, Pepe PE, Scheppke KA, Russinoff IM, Erdman D, Nugent TL, Rudbeck B, Bouchillon H, Fernandez JR. Validation of a successful approach for improving EMS resuscitation rates for out-of-hospital cardiac arrest. If accepted, Prehosp Emerg Care 2018;22 (to be in press). Submitted to the Annual Meeting of the National Association of EMS Physicians (NAEMSP), Jan. 2018, San Diego, CA. Antevy PM, Scheppke K, Cardona J, Toolan S, Maraj S, Babinec F, Corona J, Pepe PE. Reducing 9-1-1 system over-utilization through a targeted community paramedic hospice referral program. If accepted, Prehosp Emerg Care 2018;22 (to be in press). Submitted to the Annual Meeting of the National Association of EMS Physicians (NAEMSP), January 2018, San Diego, CA.

Currently Planned for the Society for Academic Emergency Medicine (SAEM):

Banerjee, Pepe PE, Paley R, et al. Survival outcomes before and after implementation of a standardized age-based resuscitation tool for pediatric out-of-Hospital cardiac arrest. If accepted, will appear in Acad Emerg Med 2018 and presented at the Annual Meeting of the Society for Academic Emergency Medicine (SAEM), May 2018 in Indianapolis, IN

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VIII. Scientific, Published Abstracts from National Institutes of Health (NIH) Resuscitation Outcomes Consortium (ROC) --- Co-Principal Investigator / Steering Committee Member

Zive D, Daya M, Koprowicz K, Cummins J, Sears G, Schmidt T, Stephens S, Stiell I. Site variation in EMS Treatment, Transport and Survival in relation to Restoration of Spontaneous Circulation (ROSC) for Adult Out-of-Hospital Cardiac Arrest: The Resuscitation Outcomes Consortium (ROC) Epistry. Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Nichol G, Thomas E, Aufderheide T, Brown T, Callaway C, Davis D, Dreyer J, Hedges J, Idris A, Lowe R, Powell J, Rea T, Stiell I, and the ROC Investigators. Incidence and outcome of out-of-hospital cardiac arrest in a large population-based cohort. Observations from the Resuscitation Outcome Consortium. Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Newgard C, Rudser K, Hedges J, Bulger E, Stiell I, Davis D, Morrison L, Kerby J, Terndrup T, Minei J, Emerson S and the Resuscitation Outcomes Consortium. Improving the Prehospital Trauma Triage Guidelines for Physiologic Derangement: Can We Do Better? Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Rea T, Cook A, Aufderheide T, Beaudoin T, Bigham B, Callaway C, Chugh S, Davis D, Idris A, Morrison L, Nichol G, Powell J, Stiell I, Terndrup T, Thiruganasambandamoorthy V, Wittwer L. Predictors of Out-of-hospital Cardiac Arrest Survival: Influence of The Utstein Measures. Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Davis D, Garberson L, Andrusiek D, Hostler D, Daya M, Pirrallo R, Craig A, Stephens S, Larsen J, Drum A, Fowler R. A Descriptive Analysis of Emergency Medical Service Systems Participating in the Resuscitation Outcomes Consortium (ROC) Network. Prehospital Emergency Care. 2007;11:369-382. (Abstract) PMID: 17907019 Christenson J, Andrusiek D, Everson-Stewart S, Kudenchuk P, Hostler D, Powell J, Callaway C, Bishop D, Vaillancourt C, Davis D, Aufderheide T, Idris A, Stouffer J, Stiell I, and the ROC Investigators. CPR Fraction Prior to Defibrillation Determines Survival in Prehospital Cardiac Arrest in the Resuscitation Outcomes Consortium (ROC) Epistry. Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Atkins D, Everson-Stewart S, Sears G, Daya M, Osmond M, Warden C, Berg R. Survival from Out-of-Hospital Cardiac Arrest is Better for Children than Adults: The ROC Epistry-Cardiac Arrest Circulation. 2007; 16(16) II_436 (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Brooks S, Schmicker R, Rea T, Aufderheide T, Davis D, Emerson S, Sahni R, Morrison L, Sears G, Griffiths D, Dorian P. Evidence for Circadian Variability in the Frequency of Out-of-Hospital Cardiac Arrest. Circulation 2007: 116(16): II_934 #53 (Abstract) Hostler D, Thomas E, Emerson S, Christenson J, Rittenberger J, Bigham B, Callaway C, Stiell I, Vilke G, Beaudoin T, Cheskes S, Davis Dan, Craig A, Gorman K, Reed A, Nichol G and the ROC Investigators. Survival after EMS witnessed cardiac arrest. Observations from the Resuscitation Outcomes Consortium (ROC) Epistry Cardiac Arrest. Circulation 2007;116 S (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, November 2007. Weisfeldt M, Griffith C, Aufderheide T, Davis D, Dreyer J, Hess E, Jui J, MacQuarrie A, Maloney J, Morrison L, Nichol G, Ornato J, Powell J, Rea T. Bystander Administered AED Shock Improves Survival from Out of Hospital Cardiac Arrest in US and Canada. Circulation. 2007; 116(16) II_385 (Abstract). Presented at the American Heart Association Scientific Session, Orlando, FL, Nov. 2007.

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Daya M, Koprowicz K, Monnig A, Zive D, Sears G, Wang H, Newgard C, Kerby J. The Resuscitation Outcomes Consortium Epistry -Frequency and Variability of Advanced Airway Management in Trauma. [Abstract] National Association for EMS Physicians annual meeting. January 2008 Newgard C, Schmicker R, Davis D, Bulger E, Nichol G, Aufderheide T, Brown T, Trickett J, Yelle J, Hata S, Minei J, Bardarson B, Gubler D, Hedges J. Revisiting the "Golden Hour": A Multi-Site Assessment of Out-of-Hospital Times and Survival Following Major Trauma. (Abstract) Academic Emergency Medicine. 2008, S103-S121, #293, Presented at SAEM, May 2008 in Washington, DC. Minei J, Schmicker R, Kerby J, Bulger E, Gubler K, Stiell I, Morrison L, Hata J, Yelle J, Cook A, Nichol G, Hoyt D and the ROC Investigators. EMS-based trauma incidence and outcome. Abstract presented at the American Association for the Surgery of Trauma (AAST) Meeting in September 2008. Bradley S, Gabriel E, Aufderheide T, Barnes R, Christenson J, Davis D, Stiell I, Nichol G, and the ROC Investigators. Survival increases with CPR before defibrillation of out-of-hospital ventricular fibrillation or ventricular tachycardia: observations from the Resuscitation Outcomes Consortium. Circulation 2008; 118 S (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008. Bigham B, Koprowicz K, Kiss A, Dorian P, Emerson S, Zhan C, Rea T, Aufderheide T, Powell J, Cheskes S, Davis D, Stouffer J, Perry J, Lees M and Morrison L. Survival unchanged five months after implementing the 2005 AHACPR and ECC guidelines for out-of-hospital cardiac arrest. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008; Circulation. 2008;118:S_765 Abstract 2686 Stiell I, Callaway C, Christenson J, Larsen J, Cheskes S, Nichol G, Hess E, Bigham B, Morrison L, Vaillancourt C, Powell J, Davis D, and the ROC Investigators. What is the Role of Chest Compression Depth During Out-of-Hospital CPR? Circulation 2008; 118 S (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008. Weisfeldt M, Sitlani C, Rea T, Atkins D, Aufderheide T, Bigham B, Brooks S, Foerster C, Gray R, Moran P, Ornato J, Powell J, Van Ottingham L, Morrison L. Patients with an AED Applied by a Bystander in a Public Setting have a Strikingly Higher Frequency of VT/VF than Observed Cardiac Arrests in the Home. Circulation. 2008;118:S_1481 Abstract P169. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008. Bigham B, Aufderheide T, Donn S, Stouffer J, Powell J, Suffoletto B, Davis D, Nafziger S, Idris A, Helbock M and Morrison L. Barriers to guideline implementation: A qualitative survey of emergency medical services. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008. Circulation. 2008;118:S_822 Abstract 4034 Bigham B, Koprowicz K, Stouffer J, Aufderheide T, Donn S, Powell J, Davis D, Nafziger S, Suffoletto B, Idris A, Helbock M and Morrison L. EMS agencies implemented the 2005 AHA guidelines for CPR and ECC an average of 416 days after their release. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, Nov 2008. Circulation.;118:S822 Abstract 4033 Reinier K, Chugh S, Thomas E, Rea T, Emerson S, Aufderheide T, Callaway C, Idris A, Stiell I. Socioeconomic disparities in sudden cardiac arrest: analysis of US metropolitan areas within the Resuscitation Outcomes Consortium. Circulation 2008; 118 S (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2008. Vaillancourt C, Everson-Stewart S, Christenson J, Andrusiek D, Powell J, Nichol G, Cheskes S, Aufderheide T, Berg B, Stiell I, and the ROC Investigators. Increased chest compression fraction is associated with increased return of spontaneous circulation in nonventricular fibrillation out-of-hospital cardiac arrest victms. Abstract accepted to Society for Academic Emergency Medicine annual meeting, May 14-17, 2009, New Orleans.

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Sugarman J, Sitlani C, Andrusiek D, Aufderheide T, Bulger E, Davis D, Hoyt D, Idris A, Kerby J, Powell J, Schmidt T, Slutsky A, Sopko G, Stephens S, Williams C, Nichol G. Is the Enrollment of Racial and Ethnic Minorities in Research in the Emergency Setting Equitable? Abstract accepted to Society for Academic Emergency Medicine annual meeting, May 14-17, 2009, New Orleans. Cudnik M, Schmicker R, Thomas L, Newgard C, Loew R, Christensen J, Davis D, Vaillancourt C, Cook A. A Geospatial Assessment of Transport Distance and Survival to Discharge in Out of Hospital Cardiac Arrest Patients: Implications for Resuscitation Centers. Abstract accepted to Society for Academic Emergency Medicine annual meeting, May 14-17, 2009, New Orleans. Vaillancourt C, Everson-Stewart S, Christenson J, Andrusiek D, Powell J, Nichol G, Cheskes S, Aufderheide T, Berg B, Stiell I, and the ROC Investigators. Does Chest Compression Fraction predict the likelihood of a shockable cardiac arrest rhythm (and ROSC? and survival?) after at least one minute of CPR? Abstract accepted to Canadian Association of Emergency Physicians meeting in Calgary June 6-10, 2009. Bulger E, Emerson S, Coimbra R, May S, Stiell I, Schreiber M, Brasel K, Kerby J, Tisherman S, Rizoli S, Minei J, Sopko G, Hata S, Evans D, Hoyt D, and the ROC Investigators. Prehospital Hypertonic Resuscitation following Traumatic Hypovolemic Shock: A Randomized, Placebo Controlled Trial. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2009 Hostler D, Everson-Stewart S, Rea T, Stiell I, Callaway C, Kudenchuk P, Sears G, Emerson S, Da Ponti M, Nichol G and the ROC Investigators. Enhancing CPR performance during cardiac arrest resuscitation: A prospective trial of real-time feedback. Presented at the American Heart Association Resuscitation Science Symposium, New Orleans, LA, November 2009. Aufderheide TP, Nichol G, Rea TD, Everson-Stewart S, Leroux B, Kudenchuk PJ, Christenson J, Pepe PE, Daya MR, Dorian P, Callaway CW, Idris AH, Andrusiek D, Stephens SW, Hostler D, Davis DP, Dunford JV, Pirrallo RG, Stiell IG, Clement CM, Craig A, Van Ottingham L, Schmidt TA, Wang H, Weisfeldt ML, Ornato JP, Sopko G, and the Resuscitation Outcomes Consortium (ROC) Investigators: The Resuscitation Outcomes Consortium (ROC) PRIMED Impedance Threshold Device (ITD) cardiac arrest trial: A prospective, randomized, double-blind, controlled clinical trial. Circulation, 2010; 122(21):S2225 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, IL, November 2010. Rac VE, Schmicker RH, Weisfeldt M, Bigham BL, Berg R, Topjian A, Abramson B, Atkins D, Morrison LJ, and the ROC Investigators. Effect of Gender on Outcome of Out of Hospital Cardiac Arrest in the Resuscitation Outcomes Consortium. Circulation. 2010; 122:A61 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, IL, November 2010. Stiell IG, Nichol G, Leroux BG, Rea TD, Ornato JP, Powell J, Christenson J, Callaway CW, Kudenchuk PJ, Aufderheide TP, Idris AH, Daya M, Wang HE, Morrison L, Davis D, Andrusiek D, Stephens S, Cheskes S, Schmicker RH, Fowler R, Vaillancourt C, Hostler D, Zive D, Pirrallo RG, Vilke G, Sopko G, Weisfeldt M, and the Resuscitation Outcomes Consortium (ROC) Investigators. Resuscitation Outcomes Consortium (ROC) PRIMED trial of early rhythm analysis versus later analysis in out-of-hospital cardiac arrest. Circulation, 2010; 122(21):S2226 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, IL, November 2010. Idris AH, Nichols P, Schroeder D, Everson-Stewart S, Powell JL, Callaway CW, Morrison L, Aufderheide TP, Rea T, Atkins D, Berg R, Bigham B, Davis D, Stiell I, Sopko G, Nichol G, The Resuscitation Outcomes Consortium Investigators. Chest Compression Rates Used During Out-of-Hospital Cardiopulmonary Resuscitation in Nine Resuscitation Outcomes Consortium Regional Sites. Circulation. 2010; 122:A246 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, IL, November 2010.

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Cheskes S, Schmicker RH, Christenson J, Menegazzi JJ, Rea T, Powell J, May S, Van Ottingham L, Salcido DD, Olsufka M, Pennington S, Simonini J, Allendes F, Edelson D, Stiell I, Berg RA, Idris A, Sell R, Bigham B, Morrison L, and the ROC investigators. Peri-shock pause: An independent predictor of survival from out-of-hospital shockable cardiac arrest. Circulation 2010;122:A266 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, Nov 2010. Reinier K, Thomas E, Andrusiek DL, Aufderheide TP, Brooks SC, Callaway CW, Pepe PE, Rea TD, Schmicker RH, Vaillancourt C, Chugh SS. Socioeconomic disparities and burden of sudden cardiac arrest in metropolitan areas: A USA-Canada comparative analysis. Circulation. 2010; 122:A18723 (Abstract). Presented at the American Heart Association Resuscitation Science Symposium, Chicago, IL, November 2010 Wang HE, Szydlo D, Sotouffer JA, Lin S, Carlson JN, Vaillancourt C, Sears G, Verbeek RP, Fowler R, Idris AH, Koenig K, Christenson J, Minokadeh A, Brandt J, Rea T, and the ROC Investigators. Endotracheal intubation versus supraglottic airway insertion in out-of-hospital cardiac arrest. (Abstract). Presented at the National Association of EMS Physicians Annual Meeting, Tucson, AZ, January 2012.

Wang HE, Brown SP, MacDonald RD, Dowling SK, Lin S, Davis D, Schreiber MA, Powell J, van Heest R, Daya M. Impact of out-of-hospital advanced airway management on outcomes after traumatic brain injury and hemorrhagic shock. (Abstract). Presented at the National Association of EMS Physicians Annual Meeting, Tucson, AZ, January 2012.

Wang HE, Devlin S, Sears GK, Vaillancourt C, Morrison L, Weidfeldt M, Callaway CW. Regional variations in early and late survival after out-of-hospital cardiac arrest. (Abstract). Presented at the National Association of EMS Physicians Annual Meeting, Tucson, AZ, January 2012.

Salcido DD, Koller AC, Sundermann ML, Callaway CW, Menegazzi JJ, and the ROC Investigators. Incidence and outcomes of unresolved prehospital rearrest in EMS-treated cases of out-of-hospital cardiac arrest. Circulation. 2012; 126:A68 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Callaway CW, Schmicker R, Brown SP, Albrich M, Andrusiek DL, Aufderheide TP, Christenson J, Daya MR, Falconer D, Husa R, Idris AH, Ornato JP, Rittenberger JC, Stiell IG, Rac VE, Rea TD, Sears G, and the ROC Investigators. Association of hospital care with survival and functional recovery after out-of-hospital cardiac arrest. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Andrusiek DL, Szydlo D, Schreiber M, Brase K, Minei J, van Heest R, Warren S, May S, and the ROC Investigators. Prehospital intubation results in increases in pulmonary infection in traumatically injured patients. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Tisherman S, Brasel KJ, Bulger EM, Kerby J, Minei JP, Powell J, Reiff DA, Rizoli S, Schmicker R, Schreiber M. Details description of all deaths in both the shock and traumatic brain injury cohorts of the Resuscitation Outcomes Consortium hypertonic saline trials. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Stiell IG, Brown S, Callaway CW, Nichol G, Aufderheide TP, Cheskes S, Vaillancourt C, Hostler D, Davis DP, Idris AH, Christenson J, Morrison LJ, Stouffer J, Free C. What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients? (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

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Idris AH, Guffey D, Pepe PE, Brown SP, Aufderheide TP, Brooks SC, Callaway CW, Christenson J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K, Sopko G, Stiell IG, Nichol G, and the ROC Investigators. The interaction of chest compression rates with the impedance threshold device and association with survival following out-of-hospital cardiac arrest. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Idris AH, Meier E, Brasel K, Daya M, Egan D, Kannas D, Kerby J, Lin S, McLeod B, Minei J, Newgard C, Reiff D, Trickett J, van Heest R, Wittwer L, Bulger E, and the ROC Investigators. Prehospital hypotension is associated with emergent in-hospital procedures and mortality in trauma patients. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Idris AH, Guffey D, Aufderheide TP, Brown SP, Pepe PE, Daya MR, Davis DP, Stiell IG, Menegazzi J, Callaway C, Christenson J, Gray R, Brooks S, Larsen J, Lin S, Sheehan K, Judenchuk PJ, Sopko G, Nichol G, and the ROC Investigators. The interaction of chest compression rates with impedance threshold device and association with survival following out-of-hospital cardiac arrest. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, November 2012.

Guyette F, Meier E, McKnight B, Powell J, Bulger E, Klotz P, Fabian T, Daya M, Newgard C, Weinberg J, Brasel K, Mena-Munoz J, Collela MR, Idris A, Beason J, Kerby J, VanHeest R, Williams C, Hoyt D, Wheeler S, and the ROC Investigators. Prehospital lactate is superior to systolic blood pressure for predicting the need for resuscitative care in trauma. (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2012 Scientific Sessions, Los Angeles, CA, Nov. 2012.

Cheskes S, Schmicker RH, Powell J, May S, Menegazzi J, Salcido D, Verbeek R, Vaillancourt C, Brooks S, Berg B, Idris A, Sell R, Kampp M, Schmidt T, Owens P, Christenson J, and the ROC Investigators. The impact of peri-shock pause on survival from out of hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium (ROC) PRIMED trial. (Abstract). Presented at the Canadian Association of Emergency Physicians, Vancouver, British Columbia, June 2013.

Stiell IG, Brown S, Callaway CW, Nichol G, Aufderheide TP, Cheskes S, Vaillancourt C, Hostler D, Davis DP, Idris AH, Christenson J, Morrison LJ, Stouffer J, Free C. What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients? (Abstract). Presented at the National Association of EMS Physicians Annual Meeting, Bonita Springs, FL, January 2013.

Elterman J, Brasel K, Brown S, Bulger E, Christenson J, Kerby JF, Minei JP, Rizoli S, Schreiber MA. Transfusion of red blood cells in patients with a pre-hospital GCS less than or equal to 8 and no evidence of shock is associated with worse outcomes. (Abstract). Presented at the Eastern Association for the Surgery of Trauma annual meeting, Scottsdale, AZ, January 2013. Cheskes S, Schmicker RH, Powell J, May S, Menegazzi J, Salcido D, Verbeek R, Vaillancourt C, Brooks S, Berg B, Idris A, Sell R, Kampp M, Schmidt T, Owens P, Christenson J, and the ROC Investigators. The impact of peri-shock pause on survival from out of hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium (ROC) PRIMED trial. (Abstract). Presented at the Canadian Association of Emergency Physicians, Vancouver, British Columbia, June 2013.

Daya M, Schmicker R, Zive D, Brooks S, Buick J, Christenson J, Craig A, Davis D, MacPhee R, May S, Nichol G, Rea T, Rittenberger J, Wigginton J, Wang H. Secular trends in community cardiac arrest survival: results from the Resuscitation Outcomes Consortium (ROC). Circulation 2013;128:A5 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2013 Scientific Sessions, Dallas, TX, November 2013

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Zelnick L, Morrison L, Devlin S, Bulger E, Brasel K, Sheehan K, Minei J, Kerby J, Tisherman S, Rizoli S, Karmy-Jones R, van Heest R, Newgard C, and the ROC Investigators. Evaluating the challenges of obtaining functional outcomes in traumatic brain injury research: timing of follow-up, prognostic models, and missing data. Circulation 2013;128:A360 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2013 Scientific Sessions, Dallas, TX, November 2013.

Rea T, Prince D, Morrison L, Callaway C, Aufderheide T, Daya M, Stiell I, Christenson J, Powell J, Warden C, Van Ottingham L, Kudenchuk P, Weisfeldt M. Early versus late EMS rhythm analysis in out-of-hospital cardiac arrest: do agency-level factors influence outcomes? Circulation. 2013;128:A18 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2013 Scientific Sessions, Dallas, TX, November 2013.

Morrison LJ, Devlin S, Kontos MC, Cheskes S, Thomas AJ, Stiell IG, Ornato JP, Christenson J, Rac VE, Aufderheide TP, Wigginton JG, Dorian P, and the ROC Investigators. The relationship of maximum Troponin values post out-of-hospital cardiac arrest with electrocardiographic findings, cardiac procedures, and survival to discharge: a sub-study of ROC PRIMED. (Abstract). Circulation 2013; 128:A233 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2013 Scientific Sessions, Dallas, TX, November 2013.

Nichol G, Guffey D, Stiell IG, Leroux B, Cheskes S, Idris A, Kudenchuk PJ, MacPhee R, Wittwer L, Rittenberger JC, Rea TD, Sheehan K, Rac VE, Raina K, Gorman KR, Aufderheide T, and the ROC Investigators. Post-discharge outcomes after resuscitation from out-of-hospital cardiac arrest: a ROC PRIMED substudy. Circulation 2013; 128:2704-2722 (Abstract). Presented at Resuscitation Science Symposium at American Heart Association 2013 Scientific Sessions, Dallas, TX, November 2013.

Guyette FX, Meier E, Kerby J, Williams C, Schlamp R, Wang R, McMullan J, Kannas D, May S, Daya M, Ibrahim-Zada I, Moffat M, Brasel K, Colella R, Fabian T, Mena-Munoz J, Bulger E, Rokowski L, Brennan S, Whitford R, Sopko G, Hoyt D, and the ROC Investigators. Prehospital lactate for the identification of the need for resuscitative care in trauma patients transported by air. Circulation 2014; Oral Presentation on Sunday, November 16, 2014 at 10:30am at

“Best of the Best” Abstract Presentations at ReSS. Cheskes S, Schmicker RH, Rea T, Powell J, Drennan IR, Kudenchuk P, Vaillancourt C, Conway W, Stiell I, Stub D, Davis D, Alexander N, Christenson J, and the ROC Investigators. The impact of chest compression fraction on clinical outcomes from shockable out-of-hospital cardiac arrest during the Resuscitation Outcomes Consortium (ROC) PRIMED trial. Circulation 2014: Poster – presented November 16, 2014, 8-9:30 a.m. Stub D, Schmicker R, Anderson M, Peterson E, Callaway C, Daya M, Elmer J, Grunau B, Aufderheide T, Lin S, Buick J, Zive D, Sayre M, Graham Nichol, and the ROC Investigators. Association between hospital post-resuscitative performance and clinical outcomes in patients with out-of-hospital cardiac arrest. Circulation 2014: Poster – presented 11/15/14 at ReSS, Chicago IL Brooks SC, Schmicker RH, Cheskes S, Christenson K, Craig A, Daya M, Kudenchuk PJ, Nichol G, Zive D, Morrison LJ, and the ROC Investigators. Variability in treated versus untreated out-of-hospital cardiac arrest episodes across the Resuscitation Outcomes Consortium. Circulation 2014; Oral presentation – presented 11/16/14 at ReSS, Chicago IL Kurz MC, Prince D, Christenson J, Carlson J, May S, Stub D, Cheskes S, Lin S, Aziz M, Austin M, Vaillancourt C, Colvin J, Wang HE, and the ROC Investigators. Supraglottic airway use is associated with higher chest compression fraction than endotracheal intubation during out-of-hospital cardiopulmonary arrest. Circulation 2014: Poster – presented 11/16/14 at ReSS, Chicago IL Salcido DD, Koller AC, Torres C, Orkin AM, Schmicker RH, Morrison LJ, Nichol G, Stephens S, Menegazzi JJ, and the ROC Investigators. Regional incidence and outcome of out-of-hospital cardiac arrest associated with overdose. Circulation 2014:Poster – presented 11/16/14 at ReSS, Chicago IL

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Drennan IR, Case E, Reynolds J, Goldberger Z, Herren H, Austin M, Jasti J, Schmicker R, Idris A, Charleston M, Leslie P, Verbeek R, Morrison L, and the ROC Investigators. An observational analysis of termination of resuscitation in the out-of-hospital setting. Circulation 2014:Poster – presented 11/15/14 at ReSS, Chicago IL Mena-Munoz J, Petersen A, Callaway C, McKnight B, Kea B, Kerby J, Kannas D, Newgard C, Schreiber M, Brasel K, Lehrfeld D, Guyette F, Goldberg S, and the ROC Investigators. Prediction of life-saving interventions using the changes in vital signs from prehospital scene to emergency department. Circulation 2014: E-Poster – presented 11/16/14 at ReSS, Chicago IL Evans CCD, Petersen A, Schreiber M, Kannas D, Buick J, Austin M, Dean D, and the ROC Investigators. Prehospital interventions associated with survival from traumatic cardiac arrest. Circulation 2014: Oral presentation – presented,11/16/14 at ReSS, Chicago IL Wigginton JG, Abdelfattah K, Pepe P, Emerson S, Gatson J, Simpkins J, Bulger E, Foreman M, Hoyt D, Kerby J, Maass D, Madden C, May S, Minei J, Powell J, Ramsey MA, Roberts K, Saner K, Schug K, Egan D, Sopko G, Warren V, Idris AH. A pilot clinical trial of single-dose estrogen for resuscitation of severe traumatic brain injury (TBI) – the RESCUE TBI study. Circulation 2014;130;2105-2126. doi: 10.1161/01.cir.0000457464.79076.2c Late-breaking clinical trials #13 – oral presentation at the ReSS American Heart Association Scientific Sessions, Chicago IL, Sunday, November 16, 2014. Wigginton J, Abdelfattah K, Gatson J, Pepe P, Emerson S, Simpkins J, Egan D, Foreman M, Hoyt D, Kerby J, Maass D, Madden C, May S, Minei J, Powell J, Ramsey M, Roberts J, Saner K, Schug K, Bulger E, Sopko G, Warren VS, Idris A. A feasibility and safety pilot clinical trial of single-dose, intravenous estrogen for resuscitation of traumatic hemorrhagic shock: Circulation 2014;130;2105-2126. doi: 10.1161/01.cir.0000457464.79076.2c Late-breaking clinical trials #32 – poster presented at the ReSS American Heart Association Scientific Sessions, Chicago IL, Saturday, November 15, 2014. ______________________________________________________________________________

SPEAKING ACTIVITIES Grand Rounds, Visiting Professorships and Lectures at State, National and international Venues as well as Local/Regional Sites

** NO LONGER LISTED in detail (due to magnitude of weekly speaking activities; was > 100 pages). MEDIA ACTIVITIES: ** NO LONGER LISTED in detail (due to magnitude of weekly national and local interviews – previous list was > 35 pages) Note: A few examples of major electronic national interviews in last several years include: ABC News World News Tonite with Charles Gibson, January 7, 2008 (5 minute segment about Parkland Emergency-Trauma Center and related philosophy of care) which won the 2008 American College of Emergency Physicians (ACEP) National Television Media Award; USA Today “Cities Move To Teach All Employees CPR”, Robert Davis, June 4, 2008; and ABC News Good Morning America live with Bill Weir, Saturday, June 7, 2008 (3.5 minute segment on knowing CPR for childhood drowning incidents); also multiple network (CNN, ESPN, Fox, ABC, NBC, CBS, AP, USA Today, etc) News Conference regarding collapse of Dallas Cowboys Valley Ranch Practice Facility and associated injuries, Saturday, May 2, 2009; Also: ABC News Interview with President Obama: Prescription for Healthcare Reform (East Wing of the White House), Wednesday, June 24, 2009; ABC World News Tonight with Diane Sawyer on the Haiti Earthquake Disaster, Monday January 18, 2010. 39 elderly patients transported after fatal bus crash (CNN, Reuters, numerous networks), April 11, 2013 and numerous live interviews during the Boston Marathon bombings and West, Texas explosion, April 15 and April 18, 2013. Also featured in several local and national media interviews during the Ebola Virus incident in Dallas, Texas, fall 2014.

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Also, served as moderator and ran numerous news conferences including those at Dallas City Hall, January 19, 2010 announcing National Institutes of Health (NIH) providing extended multi-million dollar federal funding to the Dallas area for resuscitation research and to announce accompanying dramatic rise in cardiac arrest survival rates, featuring Dr. George Sopko from the NIH NHLBI. Also, served as moderator and ran news conferences at Dallas County Medical Society, Tuesday, November 29, 2011 and Thursday, November 19, 2015 announcing roll-out of next series of studies for the National Institutes of Health Resuscitation Outcomes Consortium for the DFW area and report on dramatic rise in cardiac arrest and trauma survival rates (see Dallas Morning News, front page, November 30, 2011 “Dallas to be in emergency care studies”) and numerous electronic media (November 2015). Revised: August 1st, 2017