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Partnerships in a Changing World
Future Relationships between Publishers, Academic Libraries
and Scientists
Value as the aim
Value:• always defined by customer• If “added” but not “perceived”, it cannot be recovered• Proposition is complex
Value of Intellectual Property:• Premise: Copyright is of corporate & individual benefit• Paradox of IP: intangibility/non-depletability• Exceptions: Berne Convention, fair-dealing• IP, Value and Price
Move to network models Move from Goods to Services
Database publishing:The Alliance for Cellular Signaling
• Consortium of US cell biology groups (7 labs plus a bioinformatics centre and an editorial office)
• A 10-year effort to characterise the internal signaling mechanisms of mammalian cells
• $100m from NIGMS grant plus pharmaceutical, biotechnological and philanthropic organisations
The Signaling Gateway
Hardware & software hosted atSan Diego Supercomputer Center
Molecule Pages
AfCS Data
Center
Signaling Update
Home,Info & News
News & comment written and commissioned by NPG editors
• Facts and figures on major cell signaling proteins (3,500+)• Continually updated by selected experts (~1000)• Peer-review run by NPG
• Repository for raw experimental data from AfCS labs• Tools for viewing and analyzing data (online & offline)
The Molecule Pages
• Comprehensive, structured data for 3,500+ proteins involved in cellular signalling
• Some information automatically fed in from other online databases and updated monthly
• Other information entered by selected expert authors and updated annually
• Author-entered information to be peer-reviewed in a process run by NPG
• Will be fully citable as formal publications using DOIs and will be listed in PubMed
The Data Centre
• Half a terabyte of high-quality, internally consistent experimental data
• Includes ligand screens, yeast two-hybrid experiments and large microarray data sets
• Supplemented with detailed written reports on procedures and protocols
• Results published as soon as they are gathered – AfCS staff have no priority
• Also includes plasmid, antibody and other databases – reference works for bench scientists
Signaling Gateway innovations
• Best of both worlds: Dynamic and continually updated but also peer-reviewed and citable
• Open data sharing promotes collaborative analysis and discovery
• Open-access business model
Value-added through:
• Shift in roles: Publisher also content creator
• Publication: co-selection, co-aggregation, co-investment
• Development process: collaborative
• Access: collaborative manufacturing and technology development, automised customer service, open access
• Marketing: co-branding, user needs defined by community
The Signaling Gateway value chain