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Pancreatic Islet

Pancreatic islet

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Page 1: Pancreatic islet

Pancreatic Islet

Page 2: Pancreatic islet

What is

pancreas??

Page 3: Pancreatic islet

pancreas

It is a large gland in body that secrete hormones.

The cells that make up of pancreatic islet.

Also known as “islet of langerhans”

It is part of two different organ system

-Endocrine system

-Digestive system

Page 4: Pancreatic islet

Con’t…

There are 3 main cell in the pancreatic islet :

beta cells, which secrete insulin and amylin

alpa cells, which secrete glucagon

delta cells, which secrete somatostatin

Page 5: Pancreatic islet

Location…Whole a located in the epigastric and left hypochondriac regions and its right part lies across the bodies of L1 to L3 vertebrae.

It runs transversely across the posterior abdominal wall behind the stomach, from the duodenum to the spleen, sloping upward from right to left

It is approximately 12.5 – 15cm long and weighs from 60 – 100gm.

Page 6: Pancreatic islet

Location..

Page 7: Pancreatic islet

Structure...

(1) head of pancreas, (2) uncinate process of pancreas, (3) pancreatic notch, (4) body of pancreas, (5) anterior surface of pancreas, (6) inferior surface of pancreas, (7) superior margin of pancreas, (8) anterior margin of pancreas, (9) inferior margin of pancreas, (10) omental tuber, (11) tail of pancreas, (12) duodenum

Page 8: Pancreatic islet

Function of Insulin..

Purpose:-Regulate blood glucose (sugar) in the normal range.

Action:-Forces many cells of the body to absorb and use glucose thereby decreasing blood sugar levels.

Secreted in response- High blood glucose

Secretion inhibit by- low blood glucose

Page 9: Pancreatic islet

Function of Glucagon…Purpose:- Assist insulin in regulating blood glucose (sugar) in the normal range.

Action: Forces many cells of the body to release (or produce) glucose (increasing blood sugar).

Secreted in response to - low blood glucose

Secretion inhibit by - high blood glucose

Page 10: Pancreatic islet

SomatostatinPurpose:- Regulate the production and excretion of other endocrine hormones

Action:- produce by hypothalamus to inhibit insulin, glucagon, gastrin, and other endocrine hormones

Secreted in response to - High levels of other endocrine hormones

Secretion inhibit by- Low levels of other endocrine hormones

Page 11: Pancreatic islet

summaryResponsible for the endocrine function.

It is a large gland in body that secrete hormones.

Secreted the major hormones in the endocrine system

Page 12: Pancreatic islet

referencesWebsite(google.com)

Ross and wilson

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