Paediatric Endocrinology and Diabetes Unit Staffs

Associate Professor Dr Muhammad Yazid Jalaludin MPaeds (Head)

Dr Azriyanti Anuar Zaini MPaeds

Dr Nurshadia Samingan MPaed

Sister Siti Zarina Yaakop

Services provided

1. Inpatient services:

a. acute paediatric endocrinology management and multidisciplinary team

management of children with endocrine disorders

b. acute paediatric diabetes management

2. Comprehensive Paediatric Diabetes Management service: 5-days comprehensive

diabetes education (in-patient) for newly diagnosed diabetes or diabetes children

with poorly-controlled diabetes

3. Outpatient services:

a. paediatric endocrine clinic (growth, ambiguous genitalia, thyroid disorders,

adrenal disorders, oncology survivors with endocrinopathies, Thalassaemia

with endocrinopathies),

b. multidisciplinary paediatric diabetes clinic: dietitian, nurse educator,

psychologist

c. multidisciplinary paediatric obesity clinic: dietitian, sports medicine

d. transition clinic for late adolescents with diabetes: adult endocrinology

4. Day-care services: endocrine function tests and diabetes education/counseling

5. Paediatric Endocrinology and Diabetes Fellowship Training: accredited site.

6. Collaborative research: university, national, international (multi-centre; Investigator

Initiated and Industry-sponsored Research)

Current Research

1. Type 1 Diabetes Mellitus

a. Quality of Life and Metabolic Control in Children and Adolescents with Type 1

Diabetes

b. Diabetes Self-Care Management among Malaysian Children and Adolescents

2. Type 2 Diabetes Research

a. A 26-week open label, randomised, 2-armed, parallel group, multi-centre trial

investigating efficacy and safety of insulin detemir versus insulin Neutral

Protamine Hagedorn in combination with metformin and diet/exercise on

glycaemic control in children and adolescents with type 2 diabetes

insufficiently controlled on metformin +/- other oral antidiabetic drug(s) +/-

basal insulin

b. Efficacy and safety of liraglutide in combination with metformin versus

metformin monotherapy on glycaemic control in children and adolescents

with type 2 diabetes: A 26-week double-blind, randomised, parallel group,

placebo controlled multi-centre trial followed by a 26-week open-label

extension

c. A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled

Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose

Combination Tablet of Sitagliptin and Metformin) in Pediatric Patients with

Type 2 Diabetes Mellitus (Protocol 170)

d. A Phase III, Multicenter, Double- Blind, Randomized, Placebo- and

Metformin-Controlled Clinical Trial to Evaluate the Safety and Efficacy of

Sitagliptin in Pediatric Patients with Type 2 Diabetes Mellitus with Inadequate

Glycemic Control (Protocol 083)

e. A five year, observational, non-interventional follow up to: A phase III,

multicenter, double- blind, randomized, placebo and metformin controlled

clinical trial to evaluate the safety and efficacy of sitagliptin in pediatric

patients with type 2 diabetes mellitus with inadequate glycemic control.

Protocol No: PN351 MEC ID No: 201309-0251 MEC Ref. No : 1023.6

3. Childhood obesity research

a. Outcome of Clinic Intervention for Childhood Obesity

b. Childhood Obesity and its Impact on the Pharmacokinetics of Metformin

c. Factors Influencing Serum Concentrations of Adiponectin in Children and

Adolescents with Obesity and Diabetes

d. Systemic and Local Airway Inflammation in OSAS and Metabolic Syndrome:

collaborative research with Paediatric Respiratory Unit

4. Malaysian Health and Adolescents longitudinal Research Team Study (MyHeARTs):

Risk Factors for Chronic Non-Communicable Diseases among Adolescents

a. The Metabolic Syndrome: Prevalence and Associated Familial and Lifestyle

Risk Factors

b. Risk Factors For Vitamin D Deficiency Among Malaysian Adolescents

c. Vitamin D and Bone Density of the School Going 13-Years Old Malaysian

Adolescents

d. Prevalence of Polycystic Ovarian Syndrome (PCOS) and its Association with

Metabolic Syndrome among Adolescents in Malaysia

e. Clinical and Biochemical Characteristics of Adolescents Born Small for

Gestational Age (SGA)

5. Co-PoWR (Cohort of Paediatric Obesity Working Research): Obesity in Malaysian

adolescent population: Prevalence, risk factors, complications and intervention

a. The Role of Various Genetic Polymorphism in Childhood Obesity

b. The Association between VDR Polymorphisms and Risk of Vitamin D

Deficiency, Morbid Obesity and Insulin Resistance in Adolescents

6. My Body is Fit and Fabulous (MyBFF@school): An Intervention Programme to

Combat Obesity among Malaysian School Children

a. Effects of a 6-month Intervention Programme on the Inflammatory Markers

in a Cohort of Overweight and Obese School Children

b. Usefulness Of Body Composition Analysis and Adipokine Measurements

when Evaluating An Obesity-Intervention Programme Among School Children

7. Growth hormone research

a. Response to Recombinant Human Growth Hormone (rhGH) Therapy in

Growth Hormone Deficient (GHD) Children

b. A Multicenter Study of Endocrine Abnormalities in Septo-Optic Dysplasia

(SOD) in ASEAN Countries

8. Disorder of Sexual Development Research

a. Genetics of DSD

b. Classification of the Disorder of Sex Development (DSD) According to the

Islamic and Medical Perspectives

9. DEWI (Diabetes Empowerment in Women Initiatives): empowering women with pre-

existing diabetes and prediabetes to take responsibility for their health before and

during pregnancy to prevent progression of diabetes and development of

complications to mother and baby during pregnancy, at delivery, and over long term

10. Congenital hypothyroidism: An Audit and Study of Different Cord Blood Screening

TSH Values

11. A 10-year Retrospective Cohort Study of Term Small for Gestational Age (SGA) Babies

Born in University Malaya Medical Centre

12. Cord blood insulin, IGF-1 and its influence to body composition, adiposity and

growth of offprings of GDM and obese mothers in Malaysia: a single centre study

13. Development of a Clinical Model to Predict Adrenal Insufficiency in Children with

Nephrotic Syndrome on Steroid Treatment

14. Mother’s Practices Towards Infant Feeding and Growth

15. Vitamin D and Risk of Breast Cancer

16. Screening for early development and risks of secondary osteoporosis in children with

chronic diseases.

Fellows (Paediatric Endocrinology and Diabetes)

1. Dr Maha Abdelrazig Mohamed (1.6.2016 – 31.5.2017; Fellow from Sudan)

2. Dr Nurshadia Samingan (1.7.2015 – 30.6.2017; University Malaya Fellow: Malaysia)

3. Dr Rashdan Zaki Mohamed (1.7.2015 – 31.12.2015; Ministry of Health Fellow: Malaysia)

4. Dr Noor Shafina Mohd Nor (3.1.2012 – 31.12.2013; University Teknologi MARA Fellow:

Malaysia)

5. Dr Jeanne Wong Sze Lynn (2.1.2014 – 30.6.2014; Ministry of Health Fellow: Malaysia)

6. Dr Azriyanti Anuar Zaini (1.6.2010 – 31.12.2010 and 7.1.2014 – 10.6.2015; University Malaya

Fellow: Malaysia)

7. Dr Lim Song Hai (1.1.2011 – 30.6.2011; Ministry of Health Fellow: Malaysia)

8. Dr Suhaimi Hussain (15.1.2009 – 30.6.2010; University Sains Malaysia Fellow; Malaysia)

9. Dr Lim Poi Giok (5.1.2005 – 5.7.2005; Ministry of Health Fellow: Malaysia)

10. Dr Raja Aimee Raja Abdullah (1.7.2006 – 30.6.2007; Ministry of Health Fellow: Malaysia)

Research funding

Efficacy and safety of liraglutide in combination with metformin versus metformin

monotherapy on glycaemic control in children and adolescents with type 2 diabetes:

A 26-week double-blind, randomised, parallel group, placebo controlled multi-centre

trial followed by a 26-week open-label extension, Principal Investigator (MYJ)

NovoNordisk NN2211-3659 (2016-2019)

A 26-week open label, randomised, 2-armed, parallel group, multi-centre trial

investigating efficacy and safety of insulin detemir versus insulin Neutral Protamine

Hagedorn in combination with metformin and diet/exercise on glycaemic control in

children and adolescents with type 2 diabetes insufficiently controlled on metformin

+/- other oral antidiabetic drug(s) +/- basal insulin, Principal Investigator (MYJ)

NovoNordisk NN304-4093 (2014-2017)

A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial

to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose Combination Tablet

of Sitagliptin and Metformin) in Pediatric Patients with Type 2 Diabetes Mellitus,

Principal Investigator (MYJ); MK0431A- 170 Merck-Sharpe and Dohme (MSD) 2013-

2017

A Phase III, Multicenter, Double- Blind, Randomized, Placebo- and Metformin-

Controlled Clinical Trial to Evaluate the Safety and Efficacy of Sitagliptin in Pediatric

Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control, Principal

Investigator (MYJ); MK0431A-083 Merck-Sharpe and Dohme (MSD) 2013-2017

A five year, observational, non-interventional follow up to: A phase III, multicenter,

double- blind, randomized, placebo and metformin controlled clinical trial to

evaluate the safety and efficacy of sitagliptin in pediatric patients with type 2

diabetes mellitus with inadequate glycemic control, Principal Investigator (MYJ)

Protocol No: PN351 MEC ID No: 201309-0251 MEC Ref. No : 1023.6; Merck-Sharpe

and Dohme (MSD) 2014-2019

My Body is Fit and Fabulous: An Intervention Programme to Combat Obesity among

Malaysian School Children (MyBFF@SCHOOL): Expanded Research, Principal

Investigator (Clinical; MYJ) NMRR-13-39-16563 (Ministry of Health Grant) 2016-2018

My Body is Fit and Fabulous: An Intervention Programme to Combat Obesity among

Malaysian School Children (MyBFF@SCHOOL), Principal Investigator (Clinical, MYJ)

NMRR-13-39-16563 and H-20001-00-E000010 (Ministry of Health Grant) 2013-2015

Diabetes Empowerment of Women Initiatives (DEWI): a collaborative research with

National Diabetes Institute (NADI), Co-Investigator (MYJ) Sime Darby Foundation

2015-2017

Malaysian Health and Adolescents longitudinal Research Team Study (MyHeARTs):

Risk Factors For Vitamin D Deficiency In Malaysian Adolescents, Co-Principal

Investigator (MYJ) RP022C-14HTM (UM Research Program) 2012-2016

Systemic and Local Airway Inflammation in OSAS and Metabolic Syndrome, Co-

Investigator (MYJ, AAZ) RP025-14HTM (UM Research Program) 2014-2017

Obesity in Malaysian adolescent population: Prevalence, risk factors, complications

and intervention, Co-Investigator (MYJ) HIRMOHE H20001-00-E00062 and E000049-

200001 (HIR Grant) 2013-2016

Cord blood insulin, IGF-1 and its influence to body composition, adiposity and

growth of offprings of GDM and obese mothers in Malaysia: a single centre study,

Principal Investigator (NS) RG338-15AFR (UM Research Grant) 2015-2016

Development of a Clinical Model to Predict Adrenal Insufficiency in Children with

Nephrotic Syndrome on Steroid Treatment, Co-Investigator (MYJ, AAZ, NS) BK034-

2015 (BKP Grant) 2015-2016

Vitamin D and Risk of Breast Cancer in Malaysia, Co-Investigator (MYJ) RP046A-

15HTM (UM Research Program) 2016-2017

Socio-economic Inequality in the Presence Of Cardiovascular Risk Among

Adolescents, Co-Principal Investigator (MYJ) RP004C-13HTM (UM Research

Program) 2013-2015

Study of endocrine disorders in a Transfusion-dependent Thalassaemia (TDT)

population at the Paediatric Thalassaemia Services, UMMC, Principal Investigator

Postgraduate Research Fund, Cycle 2/2013 (GL: H-00000-60004-E13110) 2013-2014

Identification of Predictors for Dosing Determination of Metformin in Obese Children

and Adolescents, Co-Investigator (MYJ) RG354/11HTM (UM Research Grant) 2011-

2015

The Role of Various Genetic Polymorphism in Obesity, Co-Investigator (MYJ)

RG310/11HTM (UM Research Program) 2011-2013Hypovitaminosis D in Malaysian

Overweight/Obese Adolescents: Its Relationship with Adiposity, Insulin Sensitivity,

Metabolic Risk Factors, and Adiponectin, Principal Investigator (MYJ) RG304/11 HTM

(UM Research Grant) 2011-2013

Childhood Obesity and Metabolic Syndrome in Secondary School Children in Klang

Valley, Malaysia, Principal Investigator (AAZ) RG258/10 HTM (UM Research Grant)

2010-2012

Prevalence of Metabolic syndrome and carotid intima thickness in obese and

overweight children in UMMC. Principal Investigator Postgraduate Research Fund

(AAZ) 2008

University / National / International collaborations

University

Classification of the Disorder of Sex Development (DSD) According to the Islamic and

Medical Perspectives (UKMMC and Faculty of Islamic Studies, UKM) 2016-2017

Systemic and Local Airway Inflammation in OSAS and Metabolic Syndrome:

Paediatric Respiratory Unit, UMMC 2014-2017

Psychological Outcomes and Quality of Life of Patients with non-Congenital Adrenal

Hyperplasia (non-CAH) Disorder of Sex Development (DSD): UKMMC 2014-2016

Malaysian Health and Adolescents longitudinal Research Team Study (MyHeARTs):

Risk Factors for Chronic Non-Communicable Diseases among Adolescents: Social and

Preventive Medicine Department, UM

Co-PoWR (Cohort of Paediatric Obesity Working Research): Obesity in Malaysian

Adolescent Population: Prevalence, Risk Factors, Complications and Intervention:

Pharmacology Department, UM

Childhood Obesity and its Impact on the Pharmacokinetics of Metformin:

Department of Pharmacy, UM

Factors Influencing Serum Concentrations of Adiponectin in Children and

Adolescents with Obesity and Diabetes: Department of Pharmacy, UM

National

My Body is Fit and Fabulous (MyBFF@school): An Intervention Programme to

Combat Obesity among Malaysian School Children: Ministry of Health and Ministry

of Education, Malaysia

Response to Recombinant Human Growth Hormone (rhGH) Therapy in Growth

Hormone Deficient (GHD) Children: UKMMC, Ministry of Health (Putrajaya Hosp and

Paediatric Institute Kuala Lumpur) 2016-2017

Expert Committee for the Diabetes Empowerment of Women Initiative (DEWI): a

collaborative research with National Diabetes Institute (NADI) 2015-2019

Expert working group for Clinical Practice Guidelines (CPG) for Management of Type

1 Diabetes Mellitus in Children and Adolescents 2014-2016

Expert Committee “Priority Intervention to Reduce Obesity in Malaysia”, Ministry of

Health 2014-2016

Expert Committee “Prioritizing Nutrition Research for the 11th Malaysia Plan (2016-

2020)” 2014-2015

Academy of Science Malaysia Task Force Member on Prioritizing Food Policy Options

to Reduce Obesity in Malaysia 2011-2013

Expert working group for Clinical Practice Guidelines (CPG) for The Use of Growth

Hormone in Children and Adults 2009-2011

International

Scientific Advisor (Research) for Novo Nordisk Multicentre International Research for

type 2 diabetes in children 2016-2018

Genetics of Disorders of Sex Development (DSD): collaborative research with

National Health Institute Tokyo, Japan 2016-2017

Scientific Advisor (Research) for Merck Sharpe and Dohme (MSD) Multicentre

International Research for type 2 diabetes in children 2015-2019

A Multicenter Study of Endocrine Abnormalities in Septo-Optic Dysplasia (SOD) in

ASEAN Countries: ASEAN study group from Thailand, Indonesia, Philippines,

Malaysia, Vietnam 2014-2017

Selected publications

1. Dietary Intake among Adolescents in a Middle-Income Country: An Outcome from

the Malaysian Health and Adolescents Longitudinal Research Team Study (the

MyHeARTs Study). Hazreen Abdul Majid, Liyana Ramli, Sim Pei Ying, Tin Tin Su,

Muhammad Yazid Jalaludin, Nabilla Al-Sadat Abdul Mohsein. PLOS ONE |

DOI:10.1371/journal.pone.0155447 May 17, 2016

2. Noor Shafina Mohd Nor and Muhammad Yazid Jalaludin. A rare 47 XXY/46 XX

mosaicism with clinical features of Klinefelter syndrome. International Journal of

Pediatric Endocrinology (2016) 2016:11, DOI 10.1186/s13633-016-0029-3

3. Loh DA, Moy FM, Zaharan NL, Jalaludin MY, Mohamed Z. Sugar-sweetened beverage

intake and its associations with cardiometabolic risks among adolescents. Pediatr

Obes. 2016 Feb 4. doi: 10.1111/ijpo.12108.

4. Zain SM, Mohamed Z, Jalaludin MY, Fauzi F, Hamidi A, Zaharan NL. Comprehensive

evaluation of the neuropeptide-y gene variants in risk of obesity: A case-control

study and meta-analysis. Pharmacogenetics and Genomics. 2015;25(10):501-10

5. Sze Lyn Jeanne Wong, Muhammad Yazid Jalaludin, Azriyanti Anuar Zaini, Nurshadia Samingan, and Fatimah Harun. Congenital Hypothyroidism: An Audit and Study of Different Cord Blood Screening TSH Values in a Tertiary Medical Centre in Malaysia. Advances in Endocrinology Volume 2015, Article ID 387684, http://dx.doi.org/10.1155/2015/387684

6. Dahlui M, Jahan NK, Majid HA, Jalaludin MY, Murray L, Cantwell M, Su TT, Nabilla Al-

Sadat N. (2015) Risk and Protective Factors for Cigarette Use in Young Adolescents in

a School Setting: What Could Be Done Better? PLoS One. 2015 Jun

11;10(6):e0129628. doi: 10.1371/journal.pone.0129628. eCollection 2015

7. Ching Chin Lee, Fatimah Harun, Muhammad Yazid Jalaludin, Choon Han Heh, Rozana

Othman, Sarni Mat Junit. Prevalence of c.2268dup and detection of two novel

alterations, c.670_672del and c.1186C>T, in the TPO gene in a cohort of Malaysian

Chinese with thyroid dyshormonogenesis BMJ Open 2015;5:e006121.

doi:10.1136/bmjopen- 2014-006121

8. K. S. Alatzoglou, A. Azriyanti, N. Rogers, F. Ryan, N. Curry, C. Noakes, P. Bignell, G. W.

Hall, A. S. Littooij, D. Saunders, P. Thomas, H. Stewart and M. T. Dattani. SOX3

deletion in mouse and human is associated with persistence of the craniopharyngeal

canal. The Journal of Clinical Endocrinology and Metabolism 99 (12), E2702-E2708;

2014

9. Fadzlina AA, Harun F, Nurul Haniza MY, Al Sadat N, Murray L, Cantwell MM, Su TT,

Majid HA, Jalaludin MY. *Metabolic syndrome among 13 year old adolescents:

prevalence and risk factors BMC Public Health. 2014;14 Suppl 3:S7. doi:

10.1186/1471-2458-14-S3-S7. Epub 2014 Nov 24.

10. Hazreen M, Su T, Jalaludin M, Dahlui M, Chinna K, Ismail M, Murray L, Cantwell M,

Sadat N; MyHeART Study Group (2014) An exploratory study on risk factors for

chronic non-communicable diseases among adolescents in Malaysia: overview of the

Malaysian Health and Adolescents Longitudinal Research Team study (The MyHeART

study). BMC Public Health. 2014 Nov 24;14 Suppl 3:S6. doi: 10.1186

11. Hanifah R, Majid H, Jalaludin M, Al-Sadat N, Murray LJ, Cantwell M, Su T, Nahar A

(2014)Fitness level and body composition indices: cross-sectional study among

Malaysian adolescent. BMC Public Health. 2014 Nov 24;14 Suppl 3:S5. doi: 10.1186

12. Sim PY, Su TT, Majid HA, Nahar AM, Jalaludin MY (2014) A comparison study of

portable foot-to-foot bioelectrical impedance scale to measure body fat percentage

in Asian adults and children. Biomed Res Int. 2014;2014:475659. doi:

10.1155/2014/475659. Epub 2014 Aug 28.

13. Su, T. T., Sim, P. Y., Nahar, A. M., Majid, H. A., Murray, L. J., Cantwell, M. M., AL-

Sadat, N. & Jalaludin, M. Y. 2014. Association between self- reported physical activity

and indicators of body composition in Malaysian adolescents. Prev Med. 2014

Oct;67:100-5. doi: 10.1016/j.ypmed.2014.07.001. Epub 2014 Jul 10.

14. Ali JM, Jalaludin MY, Harun F. Late onset X-linked adrenal hypoplasia congenita with

hypogonadotropic hypgonadism due to a novel 4-bp deletion in exon 2 of NR0B1. J

Pediatr Endocrinol Metab. 2014 Nov;27(11-12):1189-92. doi: 10.1515/jpem-2014-

0161

15. Marcelle Simeonovic, Azriyanti Anuar, Julie Edge, Tafadzwa Makaya. Lipoatrophy: re‐emerging with analogue insulins. Is there a link with CSII? Practical Diabetes, May 2014; 31(4): 164-166

16. Lee CC, Harun F, Jalaludin MY, Lim CY, Ng KL, Mat Junit S. Functional analyses of

C.2268dup in thyroid peroxidase gene associated with goitrous congenital

hypothyroidism. Biomed Res Int. 2014;2014:370538. doi: 10.1155/2014/370538.

Epub 2014 Mar 17

17. Lee CC, Harun F, Jalaludin MY, Heh CH, Othman R, Kang IN, Mat Junit S. Variable

clinical phenotypes in a family with homozygous c.1159G>A mutation in the thyroid

peroxidase gene. Horm Res Paediatr. 2014;81(5):356-60. doi: 10.1159/000359922.

Epub 2014 Apr 4

18. Abu Hanifah R, Mohamed MN, Jaafar Z, Mohsein NA, Jalaludin MY, Majid HA, Murray

L, Cantwell M, Su TT. The correlates of body composition with heart rate recovery

after step test: an exploratory study of Malaysian adolescents. PLoS One. 2013 Dec

5;8(12):e82893. doi: 10.1371/journal.pone.0082893. eCollection 2013.

19. Tay CG, Jalaludin MY, Low WY, Lim CT. Cross-cultural adaptation and validation of

the Malay language version of the TZO-AZL Preschool Children Quality of Life

questionnaire: A health-related quality of life instrument for preschool children. J

Child Health Care. 2015 Jun;19(2):167-81. doi: 10.1177/1367493513503583. Epub

2013 Oct 23.

20. Rajagopal R, Lum SH, Jalaludin MY, Krishnan S, Abdullah WA, Ariffin H.

Hypercalcaemia: an unusual presenting feature of childhood acute lymphoblastic

leukaemia. Br J Haematol. 2013 Oct;163(2):147. doi: 10.1111/bjh.12500. Epub 2013

Aug 21. No abstract available.

21. Lee CC, Harun F, Jalaludin MY, Heh CH, Othman R, Mat Junit S. A Novel, Homozygous

c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian

Sisters with Congenital Hypothyroidism and Multinodular Goiter. Int J Endocrinol.

2013;2013:987186. doi: 10.1155/2013/987186. Epub 2013 Apr 29.

22. Hussain S, Mohd Ali J, Jalaludin MY, Harun F. Permanent neonatal diabetes due to a

novel insulin signal peptide mutation. Pediatr Diabetes. 2013 Jun;14(4):299-303. doi:

10.1111/pedi.12011. Epub 2013 Jan 28.

23. Jalaludin M, Fuziah M, Hadhrami M, Janet YH, Jamaiyah H, Mohamad Adam B.

Reliability and validity of the Malay translated version of diabetes quality of life for

youth questionnaire. Malays Fam Physician. 2013 Apr 30;8(1):12-9. eCollection 2013.

24. Herold KC, Gitelman SE, Willi SM, Gottlieb PA, Waldron-Lynch F, Devine L, Sherr J,

Rosenthal SM, Adi S, Jalaludin MY, Michels AW, Dziura J, Bluestone JA. Teplizumab

treatment may improve C-peptide responses in participants with type 1 diabetes

after the new-onset period: a randomised controlled trial. Diabetologia. 2013

Feb;56(2):391-400. doi: 10.1007/s00125-012-2753-4. Epub 2012 Oct 21.

25. Jalaludin M, Fuziah M, Hong J, Mohamad Adam B, Jamaiyah H. Reliability and Validity

of the Revised Summary of Diabetes Self-Care Activities (SDSCA) for Malaysian

Children and Adolescents. Malays Fam Physician. 2012 Aug 31;7(2-3):10-20.

eCollection 2012.

26. Khaw KW, Jalaludin MY, Suhaimi H, Harun F, Subrayan V. Endogenous Cushing

syndrome from an ectopic adrenocorticotropic hormone production as a rare cause

of ocular hypertension. J AAPOS. 2010 Aug;14(4):356-7. doi:

10.1016/j.jaapos.2010.04.009. Epub 2010 Jul 16.

27. Abidin AS, Jalaluddin MY. Left hand compartment syndrome: a rare complication of henoch schonlein purpura. J Paediatr Child Health. 2008 Jun;44(6):385. doi: 10.1111/j.1440-1754.2008.01312.x.

Activities/Courses 1. Annual Diabetes Camp

a. UMMC Diabetes Camp 2016 Date: 16-18 March 2016 Venue: Eight Acres, Raub Pahang Theme: “My Greener Diabetes”

b. National Diabetes Camp 2015 Date: 25-27 November 2015 Venue: Suria City Hotel and Legoland, Johore Bahru Theme: Oh My Glucose!!! (OMG)

c. UMMC Diabetes Camp 2014/2015 Date: 18-20 March 2015 Venue: Casa Titik, Cherating, Kuantan Theme: “Living with Diabetes”

d. UMMC Diabetes Camp 2013 Date: 19-21 December 2013 Venue: Avillion Admiral Cove, Port Dickson. Theme: Diabetes: "Yes, we CAN care for ourselves"

e. UMMC Diabetes Camp 2013 Date: 7-8 June 2013 Venue: Cyberview Lodge Resort & Spa, Cyberview, Cyberjaya. Theme: Diabetes: "Protect Our Future"

f. UMMC Diabetes Camp 2011 Date: 14-16 December 2011 Venue: Best Western, Lumut, Perak Theme: DIABETES... Yes we CAN!!!! care for ourselves

g. UMMC Diabetes Camp 2011

Date: 2-3 July 2011 Venue: Al Sakinah Eco Resort, Janda baik, Pahang

Theme: Helping Parents Cope with their Child's Diabetes

h. UMMC Diabetes Camp 2009

Date: 3-5 December 2009 Venue: Regency Tanjung Tuan Beach Resort, Port Dickson, Negeri Sembilan Theme: “Children with diabetes and school”

i. UMMC Diabetes Camp 2008 Date: 19-21 November 2008 Venue: Tiara Beach Resort, Port Dickson, Negeri Sembilan Theme: “I’m Diabetic! So what?”

2. Paediatric Diabetes Education Day 2015

Venue: TJ Danaraj Auditorium Date: 19-20 October 2015

3. World Diabetes Day Celebration on 14th November 2015 Paediatric Diabetes Booth Venue: UMMC Concourse Date: 14-18 November 2015

4. Masters Intensive Course Part 2 Venue: HUKM Date: 11-13 August 2015 Contribution: Invited speaker

5. Paediatric Endocrine Postgraduate Course 2014 Date: 29-30 May 2014 Venue: UMMC Theme: Practical Endocrinology

6. Monthly Regional Paediatric Endocrinology Combine Meeting/Case Presentation in UKMMC.

7. Website for Children with Diabetes: Learning about diabetes is made simpler and everything on “the go” by using this website. Comprehensive diabetes content with basic management, blood glucose profile, carbohydrate counting and e-consultation. Learning about diabetes is more interactive and this help to optimize diabetes control. Discussion during clinic session is easier to understand. Now looking for any opportunity to have a good diabetes group that can fully utilize this website especially e- consultation. This website helps to optimize the HbA1c control and diabetes care as a whole.

8. Dietary management in Diabetes Book: in collaboration with the Dietetic

Department. Lead Author: Dr Rokiah Ismail, Authors: Haszlin Hassim, Mohd Huzaini & Mimi Arifa Mohd Jun

a. Diet and Diabetes. b. A visual guide to carbohydrate and calorie counting – in progress

9. Pamphlets

a. “What?? Children can have diabetes?” “ Apa? Kanak-kanak boleh mendapat diabetes?” Pamphlets for World Diabetes Day 2014

b. “Exercise and Diabetes for children” c. Children with diabetes: reference and useful tips for school; parents and

school personnel version in English and Malay – with help of Eli-Lilly Malaysia

10. Diabetes booklet/education file A comprehensive file for newly diagnosed children with type 1 diabetes or for poorly controlled diabetes admitted for re-education. The content of the file consists of:

Contact number of health-care personnel taking care of children with diabetes

Basic understanding of type 1 diabetes: pathophysiology in a children friendly pictogram

Hypoglycaemia and how to manage it well

DKA and how to recognize the symptoms

Management of sick days

Insulin injection technique and site

Long term complications of diabetes

Exercise and diabetes

Diet Management booklet

11. Diabetes book “Lina dan Diabetes” in the midst of editing. Diabetes group UMMC.

Impact • Clinical Practice Guidelines on The Use of Growth Hormone in Children and Adults. Published in 2011 http://www.moh.gov.my/attachments/6243.pdf • A publication (book) on Prioritizing Food Policy Options to Reduce Obesity in Malaysia, by Academy of Science Malaysia 2013 http://www.youblisher.com/p/1055043-Prioritizing-Food-Security-Options-to-Reduce-Obesity-in-Malaysia/ • Clinical Practice Guidelines on Management of Type 1 Diabetes Mellitus in Children and Adolescents. To be launched November 2016. Updated paediatric endocrinology & diabetes unit: June 2016