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HTTPS://PACIFICHEM.ORG Pacifichem 2021 The International Chemical Congress of PACIFIC BASIN SOCIETIES 2021 Honolulu, Hawaii, USA; December 16 – 21, 2021 A Creative Vision for the Future Advancements in the Chemistry of Targeted Alpha Therapy (#180) Symposium Organizers: Dr. D. Scott Wilbur, [email protected]; Dr. Paul Schaffer, [email protected]; and Dr. Shigeki Watanabe, [email protected] The focus of this symposium is on advancements in chemistry associated with targeted alpha therapy (TAT) for treatment of human diseases. Targeted alpha therapy holds great potential for treatment of disseminated cancers, chemoresistant bacterial infections and viral infections. In this promising treatment approach, alpha-emitting radionuclides are combined with targeting agents to selectively kill targeted cells in patients. The overall objective of the symposium is to have presentations and discussions on recent chemical advancements in the development of TAT agents. Presentations will highlight advances in: (a) production of alpha-emitting radionuclides that have properties suitable for in vivo use, (b) chemical processes that provide efficient isolation and purification of alpha- emitting radionuclides from natural or man-made sources, including automated processes, (c) chemical studies of efficient and stable bonding or chelation of alpha-emitting radionuclides to targeting agents, and (d) preclinical evaluations of alpha-emitters coupled to targeting agents to demonstrate in vivo stability, targeting efficiency and therapeutic efficacy. PACIFICHEM 2020: 2021: A CREATIVE VISION FOR THE FUTUR E For the safety of our attendees and the surrounding community, the Pacifichem 2020 Congress has been rescheduled as the Pacifichem 2021 . Please join us Dec . 16 - 21 , 2021 in Honolulu, Hawaii, USA .

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Page 1: PACIFICHEM 2020: 2021

HTTPS://PACIFICHEM.ORG

Pacifichem 2021

The International Chemical Congress of

PACIFIC BASIN SOCIETIES 2021

Honolulu, Hawaii, USA; December 16 – 21, 2021

A Creative Vision for the Future

Advancements in the Chemistry of Targeted Alpha Therapy (#180)

Symposium Organizers: Dr. D. Scott Wilbur, [email protected]; Dr. Paul Schaffer, [email protected];

and Dr. Shigeki Watanabe, [email protected]

The focus of this symposium is on advancements in chemistry associated with targeted alpha therapy (TAT) for treatment of human diseases. Targeted alpha therapy holds great potential for treatment of disseminated cancers, chemoresistant bacterial infections and viral infections. In this promising treatment approach, alpha-emitting radionuclides are combined with targeting agents to selectively kill targeted cells in patients.

The overall objective of the symposium is to have presentations and discussions on recent chemical advancements in the development of TAT agents. Presentations will highlight advances in: (a) production of alpha-emitting radionuclides that have properties suitable for in vivo use, (b) chemical processes that provide efficient isolation and purification of alpha- emitting radionuclides from natural or man-made sources, including automated processes, (c) chemical studies of efficient and stable bonding or chelation of alpha-emitting radionuclides to targeting agents, and (d) preclinical evaluations of alpha-emitters coupled to targeting agents to demonstrate in vivo stability, targeting efficiency and therapeutic efficacy.

PACIFICHEM 2020: 2021:A CREATIVE VISION FOR THE FUTURE

For the safety of our attendees and the surrounding

community, the Pacifichem 2020 Congress has been

rescheduled as the Pacifichem 2021. Please join usDec. 16-21, 2021 in Honolulu, Hawaii, USA.

Page 2: PACIFICHEM 2020: 2021

HTTPS://PACIFICHEM.ORG

Pacifichem 2021

The International Chemical Congress of

PACIFIC BASIN SOCIETIES 2021

Honolulu, Hawaii, USA; December 16 – 21, 2021

A Creative Vision for the Future

Advancements in Isotope Production-Providing Important Materials for Research and Applications (#190)

Symposium Organizers: Dr. Ethan Balkin, [email protected]; Dr. Cornelia Hoehr,

[email protected]; Dr. Kohshin Washiyama, [email protected]

The focus of this symposium is on advancements in the production and purification of isotopes. Isotopes are essential tools in areas ranging from medical treatments to basic research and include industrial as well as international nuclear safeguards applications. The overall objective of the symposium is to have presentations and discussions on (a) the production of isotopes from different accelerators and generators routes, (b) the chemical isolation and purification of the isotopes, as well as (c) nuclear data which are essential for the production. Acceptable topics include: all aspects of targetry, radionuclide production (α, β, photon, and auger e emitters), associated chemistry and recycling methods, automation, and production related nuclear data (cross section measurements, techniques, etc.)

PACIFICHEM 2020: 2021:A CREATIVE VISION FOR THE FUTURE

For the safety of our attendees and the surrounding

community, the Pacifichem 2020 Congress has been

rescheduled as the Pacifichem 2021. Please join usDec. 16-21, 2021 in Honolulu, Hawaii, USA.

Page 3: PACIFICHEM 2020: 2021

HTTPS://PACIFICHEM.ORG

Pacifichem 2021

The International Chemical Congress of

PACIFIC BASIN SOCIETIES 2021

Honolulu, Hawaii, USA; December 16 – 21, 2021

A Creative Vision for the Future

Innovative Technologies for Production, Purification, Analysis and in Vitro Evaluation of Radiopharmaceuticals (#195)

Symposium Organizers: Dr. R. Michael van Dam, [email protected]; Dr. Giancarlo Pascali,

[email protected]; Dr. Yuji Kuge, [email protected]

Preparation of short-lived radiopharmaceuticals for imaging or therapy requires significant automation. As demand and variety of radiopharmaceuticals in use continue to increase, there is renewed interest in improving the technologies used for their production. For example, microfluidics and flow chemistry offer many advantages that can improve the yields and decrease the cost of producing radiopharmaceuticals. Recently, research in this area has been expanding to include upstream (e.g. radioisotope separation and concentration) and downstream processes (e.g. purification, formulation, analysis). Other recent innovations include automated QC testing and modular systems that increase equipment versatility. Evaluation of pharmacologic properties of radiopharmaceuticals in cell cultures or single cells via microfluidic radioassays is also now possible. This symposium will highlight the progress made in radiochemistry technology innovations and the challenges to be addressed to bring these concepts into mainstream use.

PACIFICHEM 2020: 2021:A CREATIVE VISION FOR THE FUTURE

For the safety of our attendees and the surrounding

community, the Pacifichem 2020 Congress has been

rescheduled as the Pacifichem 2021. Please join usDec. 16-21, 2021 in Honolulu, Hawaii, USA.