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Overview of Sleep PHARMAC seminars Dr Tony Fernando [email protected] Psychiatrist and Sleep Specialist Department of Psychological Medicine University of Auckland

Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

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Page 1: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Overview of Sleep

PHARMAC seminars

Dr Tony Fernando

[email protected]

Psychiatrist and Sleep Specialist

Department of Psychological Medicine

University of Auckland

Page 2: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

sleep myths

1) All of us need 8 hours

2) Snoring is common and harmless

3) If you are always tired, you are not sleeping

enough

4) You can catch up on sleep deficits during the

weekend

5) Alcohol helps you sleep

6) Students who fall asleep in class are lazy

7) If you are tired and driving, roll a window down

or turn up the radio

Page 3: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Who is sleepy at this moment?

Page 4: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Who has problems with

their sleep- difficulty

falling asleep, waking up

in the middle of the night,

poor quality sleep such

that it affects you the

following day?

Page 5: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Who are night owls-

given the chance, feel

more natural to stay

awake late, after 12

MN and sleep in until

midday?

Page 6: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Who sleep walk, sleep

talk, do unusual things

when they are asleep?

Page 7: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep disorders among

university students Samaranayake C, Arroll B, Fernando A NZ Medical Journal August 2014

Specific conditions causing sleep

symptoms

n (%) (N= 509) of 1292 University of

Auckland students

Anxiety 158 (31.0%)

Depression 153 (30.8%)

Delayed sleep phase disorder* 127 (24.9%)

Problematic alcohol use 89 (17.5%)

Parasomnias 63 (12.4%)

General health problem 53 (10.4%)

Primary insomnia* 45 (8.8%)

Obstructive sleep apnoea 12 (2.4%)

Page 8: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Why do we need to sleep?

Page 9: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Why Sleep

Body repair?

Energy replenishment?

Predator avoidance?

Thermoregulation?

Memory consolidation?

Neuronal Integrity?

Resculpting of synaptic

populations?

Maximizing adaptation to the

environment (Jerome Siegel)

Page 10: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Recent Research on Sleep and the

Brain

– Sleep improves

procedural memory

tasks requiring practice

and repetition

– Problem solving skills

– Pruning and

strengthening of

circuits that promotes

learning new things

and reinforcing old

ones

Page 11: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep per 24 Hours

-1

4

9

14

19

24

Giraffe

Elephant

Whale

Man

Baboon

Cat

Rat

Lion

Bat

Page 12: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Species that “do not sleep”

Page 13: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 14: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Total Sleep Requirement**

Sleep Academic Award 14

Page 15: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep and Life Stages

Page 16: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 17: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Complexity of Sleep

Page 18: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep Architecture

Sleep is divided into two types:

Rapid Eye Movement Sleep (REM)

Non – Rapid Eye Movement Sleep (NREM)

Scammell TE. Sleep Med Alert. 2004; Comella CL, et al. Textbook of Clinical Neurology. 1999.

Page 19: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Dreams

– Occurs mostly during the REM phase of sleep

– REM occurs about 5x a night, totaling about 2

hours

– Remember less than 5% of our dreams

– Why dream?

Erasing theory

Filing theory

Page 20: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Diagnosing Sleep Disorders

Sleep history

Sleep diary

Actigraph

Polysomnogram

Page 21: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep History

Sleep onset

Sleep latency

Interruptions

Total sleep time

Quality of sleep

Pattern long term

Sleep attacks

Sleepiness during the

day

Sleep walking

Sleep talking

Sleep eating

Sleep sex

Snoring

Violent activities

Page 22: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Auckland Sleep Questionnaire www.insomniaspecialist.com/forms.php

Page 23: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep Diary (AASM American Academy of Sleep

Medicine)

Page 24: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Polysomnogram

– Brain electrical activity

( Sleep EEG)

– Eye and jaw muscle

movement

– Leg muscle movement

– Airflow

– Respiratory effort

(chest and abdominal

excursion)

– EKG

– Oxygen saturation

Page 25: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

3 major groups of sleep

symptoms**

Sleep Symptoms

Insomnia? Excessive Daytime

Sleepiness? Parasomnias?

Page 26: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Insomnias

– Primary insomnia

– Secondary insomnias

(due to substances,

psychiatric**, medical,

neurological condition)

– Circadian rhythm

problems

– Jet lag

– Shift work Sleep

Disorder

Page 27: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Thinking style

Page 28: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Excessive Daytime Sleepiness

Difficulty in maintaining

desired wakefulness

Falling asleep at

inappropriate times

Excessive amount of

sleep

Page 29: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep Disorders EDS ( Excessive Daytime Sleepiness

conditions)

– Sleep apnoea http://www.youtube.com/watch?v=ql66pp0iq_4

http://www.youtube.com/watch?v=inmop4Kv8PI

– Idiopathic hypersomnia

– Substances

– Circadian rhythm disorder

– Sleep deprivation

– Narcolepsy/ sleep attacks

http://www.youtube.com/watch?v=l2x14qETS7E

Page 30: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Sleep Disorders

Parasomnias – Sleep walking/

somnambulism

– Sleep sex

– Sleep eating

– Sleep talking (somniloquy)

– Sleep screaming***

– REM behaviour disorders

– Periodic Limb Movements

(PLM’s)

– Restless legs

– Bruxism

Page 31: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 32: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 33: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 34: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

parasomnias

http://www.youtube.com/watch?v=z2BgjH

_CtIA (Bizkit the sleepwalking dog)

http://www.youtube.com/watch?v=hLfUB4

s72GU (ABC news on parasomnia)

Page 35: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 36: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Management of Sleep Disorders

Need to have correct diagnosis first

Multi-modal approach

– Psychological, Behavioural, Biological Cognitive Behavioural Treatment for Insomnia

– Bed Restriction Programme!!!

Light Treatment

Melatonin

Continuous Positive Airway Pressure (CPAP)

Medications

Page 37: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Bright Light Exposure

Sun.lnk

Page 38: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Countermeasures for Sleep

deprivation fatigue/ sleepiness****

SLEEP !!!

– 2-8 hr nap prior to a 24 hour sleep loss

(shiftwork)

– 15 minute naps every 2 – 3 hour intervals

– Sometimes, more than 2 hour naps can

worsen sleep inertia

Caffeine? Methamphetamine? Cocaine?

modafinil

Page 39: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Enhancing Sleep**** Address underlying medical and psychiatric condition

Basic tips – Avoiding stimulating substances ( caffeine, nicotine,

amphetamines)

– Minimizing alcohol intake

– Physical aspects of sleeping ( bed firmness, temperature, noise)

– Minimize stimulating activities at night

– Going to bed only when really sleepy ( yawning, nodding off, droopy eyelids); fatigue not necessarily same as sleepy; time to bed and waking up time are highly individualised

– Consistent time in getting out of bed

– Cutting back computer use at night; cell phones OFF

– Avoid doing anything else in bed- just sleep and sex

Page 40: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Enhancing Sleep

Calm and focused mind

– Learning mindfulness

Focusing on the present moment;

full attention to your current activity

Thursday evening meditations 530

PM; Auckland Hospital level 12

Page 41: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch
Page 42: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

calm.auckland.ac.nz

Page 43: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

sleepio.com

Page 44: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

sleepeducation.org

Page 45: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

sleephub.com.au

Page 46: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

Helpful Websites

sleepio.com

www.calm.auckland.ac.nz ( downloadable mp3’s

on meditation, relaxation, self hypnosis, positive

psychology)

www.sleepfoundation.org (general information,

patient resources on sleep and sleep disorders)

http://yoursleep.aasmnet.org/ (American

Academy of Sleep Medicine)

Auckland Sleep Questionnaire

– www.insomniaspecialist.co.nz/forms/ASQ.pdf

Page 47: Overview of Sleep PHARMAC seminars · sleep myths 1) All of us need 8 hours 2) Snoring is common and harmless 3) If you are always tired, you are not sleeping enough 4) You can catch

You can wake up now.

Talk over…

Questions?