Out With the Old and In With the New, Again?

Out With the Old, In With the New

Current Standard of Care

NEUTRINO and FISSION SOF + RBV ± pegIFN for Treatment-naive Patients

NEUTRINO and FISSION SOF + RBV ± pegIFN for Treatment-naive Patients

FUSIONSOF + RBV ± pegIFN in Treatment-experienced Patients With G2,3 HCV

VALENCESOF + RBV for 12 Weeks or 24 Weeks in G2 or G3 HCV Infection

QUEST 1 and 2Q80K Variant Adversely Affects SVR12 of SMV-based Therapy

COSMOS SOF + SIM ± RBV for G1 HCV-infected Patients by Fibrosis Stage

2014 AASLD HCV Treatment Guidelines

ION-1On the Road to IFN-free Therapy for G1 HCV

Infection

ION-3 8 Weeks or 12 Weeks of SOF/LDV for Treatment-

naive G1 HCV Infection

ION-2SOF/LDV in G1 HCV-infected Patients Failing

PegIFN/RBV ± DAA

HALLMARK-DUALPhase 3 Trial of the All-oral Regimen DCV + ASV

for G1b HCV Infection

SAPPHIRE IABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV

for G1 HCV Infection

SAPPHIRE IIABT-450/r/Ombitasvir + Dasabuvir + RBV (3D)

G1 HCV

TURQUOISE IIABT-450/r/Ombitasvir + Dasabuvir (3D) + RBV in

Cirrhosis

The Past And Future of HCV Therapy

Abbreviations

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References

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