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Complete Periodontal Therapy
"First Line" Topical Therapy for Periodontal TreatmentOral Transmucosal Patch: A new approach to manage periodontal care
07. STMN_periopatch new brochure 110718 - EN.indd 1 5-10-2018 14:25:02
Efficacy-based Periodontal Therapy:Periodontal disease is a multifactorial inflammatory disease
Periodontal disease can be effectively treated only by:
: Leading the way to better oral care.Current therapies, including scaling
and root planing, antiseptic rinses
and even subgingivally-delivered
antimicrobials, reduce bacterial load
but do not reduce inflammation
or enhance healing.
Reducing bacterial plaque
Reducing inflammation to arrest the
disease
Promoting healing to repair the damage
PerioPatch is the first product to accomplish all of these crucial objectives.
AfterBefore PerioPatch applied
07. STMN_periopatch new brochure 110718 - EN.indd 2 5-10-2018 14:25:10
% R
educ
tion
in in
flam
mat
ion
SRP only PP+SRP
p value = 0.00160%
50%
40%
30%
20%
10%
0%
Placebo PerioPatch®
p value = 0.0160%
50%
40%
30%
20%
10%
0%
-10%
% R
educ
tion
in G
CF
ß-gl
ucur
onid
ase
% o
f pat
ient
s w
ith in
crea
sed
MM
P
p value = 0.0028100%
80%
60%
40%
20%
0%
Placebo PerioPatch®
: Breakthroughin Oral CareHow Doesit Work?
PerioPatch is a topical patch that adheres and conforms to the teeth
and gums.
It protects the gingival tissue and rapidly reduces the signs and symptoms
of inflammation.
Based on new medical technology developed to accelerate healing in
chronic wounds, PerioPatch absorbs the inflammatory exudates from both
the periodontal pocket and the gingiva. The therapeutic effect is a rapid
reduction of inflammation and acceleration of the natural healing process.
PerioPatch®
(PP) reduces
inflammation 3-fold
when combined
with scaling and
root planing (SRP)
50% reduction in
GCF β-glucuronidase
(a clinical biomarker
of active inflammation)
within 24 hours
Lower levels of
MMP (an enzyme
that causes
periodontal
destruction)
with PerioPatch®
treatment
Graph 1
Graph 2
Graph 3
07. STMN_periopatch new brochure 110718 - EN.indd 3 5-10-2018 14:25:11
works from the "outside-in"Reverse patch technology designedfor oral care: adheres when moist (in mouth)and not when dry.
One treatment (6 patches): Therapeutic benefits continue for months.Benefits: Protects and relieves inflamed gums
Reduces pocket depth
Increases clinical attachment
Reduces bleeding and pain
Relieves denture sores and other oral irritation
Promotes healing after surgery and implants
Absorbs inflammatory exudates
Can be used together with scaling and root planing
for better clinical results
Can be used to manage peri-implantitis
Can be used to manage moderate recession
Rapid and long-lasting effect
Easy to use
Comfortable
Safe
Easy to apply by both professional and patient
No need for painful insertion into the inflamed periodontal pocket
Comfortable to wear
Rapid effect
Before
After
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Thousands of patients treated successfully
Natural hydrogel technology Easily integrated into current treatment regimens Safe for long term use
Centella asiatica
Sambucus nigra
Echinacea purpurea
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Dosage:PerioPatch is applied topically to the affected area 1-3 per day.
The patch will remain in place for 15 – 120 minutes and will self-release when therapeutic action is completed.
Patients should not eat, drink, or rinse when PerioPatch is adhered to the gums.
Regulatory status:PerioPatch is a registered medical device
(FDA 510(k); CE Class I)
Professor Howard Tenenbaum, DDS, PhD, Professor, Faculty of Dentistry, University of Toronto
"PerioPatch is a wonderful new product that can be used to treat periodontal disease
by reducing inflammation and promoting healing. It has become a critical part of our
periodontal treatment regimen."
Jeffrey C Hoos DMD FAGD
Success in private practice is assured when the
office performs the BALANCING act between Art,
Science, and Business.
"By adding PeriActive to our pre and post surgical
cases, everything is just better. The tissues look
healthier, heal better and post operative discomfort
is greatly reduced. Patients are extremely pleased
with the results. PerioPatch has given us another
tool to solve muco-gingival problems, as well as
post surgical comfort. With IZUN products, we
have a great partnership to help maintain the
BALANCING: Art, Science, and Business."
John Comisi, DDS, Assistent Professor, Medical University of South Carolina
Dr. Comisi recommends PerioPatch, a thin bilayer
oral patch that works together with a combination
of three botanical ingredients (Sambucus nigra,
Echinacea purpurea, and Centella asiatica) to calm any
inflammation and enhance natural oral healing.
The patch has been beneficial for his patients,
helping to reduce acute inflammation and
improve overall oral health.
What Key Opinion Leadersare saying about PerioPatch:
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Complete Periodontal Therapy (CPT)Treats all aspects of gum disease with a three-pronged approach:
Reduces bacterial plaque
Reduces inflammation
Promoteshealing
1 2 3
CPT is an Oral Care system:
Full mouth use and long-term maintenance
PerioPatch®A unique intra-oral patch for highly inflamed gums and deep pockets
1 2
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References for graphsGraph 1. Paquette DW, Levine WZ. Adjunctive Treatment of Periodontal Disease with Self-Adhesive Hydrogel Wound
Dressing: Case Series. Compend Contin Educ Dent. 2015 Jun;36(6): e12-4.
Graph 2. Samuels N, Saffer A, Wexler ID, Oberbaum M. Localized reduction of gingival inflammation using site-specific
therapy with a topical gingival patch. J Clin Dent. 2012;23(2):64-7
Graph 3. Oberbaum M, Levine WZ, Saffer AJ, Koren N, Sarment D (2016) Inhibition of matrix metalloproteinase activity by a
transmucosal patch containing botanical compounds. Dent Oral Craniofac Res 2: DOI: 10.15761/DOCR.1000175.
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DISTRIBUTED BY
Institut Straumann AGPeter Merian-Weg 12 | 4002 Basel | SwitzerlandTel +41 61 965 11 11 | Fax +41 61 965 11 01E-mail: [email protected] | www.straumann.com
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