www.biolandkorea.com TM OssGuide TM OssGuide Absorbable Collagen Membrane For GBR For Dental Surgery For Dental Surgery OssGuide TM is high purified type I collagen membrane derived from porcine tissue for guided bone regeneration. It is used as a curtain for guidance of periodontium in treatment of GBR etc being used with bone graft material (BGM) or direct as a curtain for guidance of periodontium in treatment of GBR etc., being used with bone graft material (BGM) or direct adhesion to damaged bone or periodontium. Advantage of the Product OssGuide TM has excellent tensile strength and is not easily torn. OssGuide TM is absorbed slowly and is maintained in the body for a High Quality OssGuide is absorbed slowly and is maintained in the body for a long period. High Quality Easy OssGuide TM has excellent flexibility and shows good performance on dh i d h i t th b Easy Handling adhesion and cohesion to the bones. OssGuide TM is excellent for holding a shape. OssGuide TM is fast hydrated and not easily torn while in use Convenience OssGuide is fast hydrated and not easily torn while in use. OssGuide TM can be used regardless of front and back side. Comparison with other product Comparison with other product Interior Dissolution Tensile Strength Test Product Interior Dissolution period OssGuide After 3 months Other product Within 2 months Other product Within 2 months OssGuide Other Product Osteoblast Cell Adhesion Test After the cultivation by U-2OS osteoblast cell line it is confirmed osteoblast cell line, it is confirmed by SEM that bone cell is well adhered and replicated on adhered and replicated on surface of OssGuide TM in day 3.

OssGuide (Rev.1.1) - 인쇄의뢰 [호환 모드] · In reviewing the result of micro CT in rat’s calvarial bone defect models, after 12 weeks from the operation, a bone volume

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Page 1: OssGuide (Rev.1.1) - 인쇄의뢰 [호환 모드] · In reviewing the result of micro CT in rat’s calvarial bone defect models, after 12 weeks from the operation, a bone volume

www.biolandkorea.com

TMOssGuideTMOssGuideAbsorbable Collagen Membrane For GBR

For Dental SurgeryFor Dental SurgeryOssGuideTM is high purified type I collagen membrane derived from porcine tissue for guided bone regeneration. It is used as a curtain for guidance of periodontium in treatment of GBR etc being used with bone graft material (BGM) or directas a curtain for guidance of periodontium in treatment of GBR etc., being used with bone graft material (BGM) or direct adhesion to damaged bone or periodontium.

Advantage of the Product

OssGuideTM has excellent tensile strength and is not easily torn.OssGuideTM is absorbed slowly and is maintained in the body for aHigh Quality OssGuide is absorbed slowly and is maintained in the body for a long period.

High Quality

EasyOssGuideTM has excellent flexibility and shows good performance on dh i d h i t th bEasy

Handling adhesion and cohesion to the bones. OssGuideTM is excellent for holding a shape.

OssGuideTM is fast hydrated and not easily torn while in useConvenience

OssGuide is fast hydrated and not easily torn while in use.OssGuideTM can be used regardless of front and back side.

Comparison with other productComparison with other product

Interior DissolutionTensile Strength Test

Product Interior Dissolution period

OssGuide After 3 months

Other product Within 2 monthsOther product Within 2 months

OssGuide Other Product

Osteoblast Cell Adhesion Test

After the cultivation by U-2OS osteoblast cell line it is confirmedosteoblast cell line, it is confirmed by SEM that bone cell is well adhered and replicated onadhered and replicated on surface of OssGuideTM in day 3.

Page 2: OssGuide (Rev.1.1) - 인쇄의뢰 [호환 모드] · In reviewing the result of micro CT in rat’s calvarial bone defect models, after 12 weeks from the operation, a bone volume

OssGuideTMOssGuideBone Volume, Bone Intensity Test (Rat’s Calvarial Bone Defect Model)

2 weeks 4 weeks 8 weeks 12 weeks

Micro CT

BV/TV : 0.924±0.135 BV/TV : 37.01±1.88 BV/TV : 51.64±0.331 BV/TV : 93.15±0.411

H&E Dying

* BV/TV : trabecullae volume / total volume

Tb.N : 0.544±0.059 Tb.N : 1.12±0.028 Tb.N : 1.17±0.060 Tb.N : 1.68±0.039

I i i th lt f i CT i t’ l i l b d f t d l ft 12 k f th ti b l

BV/TV : trabecullae volume / total volume* Tb.N : number of trabecullae, higher value means stronger bone intensity

► In reviewing the result of micro CT in rat’s calvarial bone defect models, after 12 weeks from the operation, a bone volume of OssGuideTM is increased up to 93.15 and bone intensity is up to 1.68. In reviewing the opinion of tissue inspection, after

►

12 weeks from the operation, OssGuideTM shows perfect bone generation.

Clinical Application of OssGuideTM

Before Application After 4 months

Application of OssGuideTMApplication of OssGuideTM

Application of Bone graft Opened, After 4 months

Ordering Information

Item Name Type Size

TG 1 15mm x 20mm

OssGuideTMTG-1 15mm x 20mm

TG-2 20mm x 30mm

TG-3 30mm x 40mm

162 GWAHAKSANEOP 3-RO, OCHANG, CHEONGWON, CHUNGBUK 363-885, KOREA * TEL:+82 43 240 8600 / FAX:+82 43 240 8619www.biolandkorea.com / [email protected] g@