ORIGINAL REASEARCH ARTICLE - CLINICAL STUDY · 2020. 1. 17. · yurveda O Ayurveda J 5 JOA journalofayurveda.in ISSN No:2321-0435 JOA XIII-3 2019 ORIGINAL REASEARCH ARTICLE - CLINICAL

Journal of Ayurveda Official publication of National Institute of Ayurveda, Jaipur, Rajasthan5

JOAjournalofayurveda.in ISSN No:2321-0435

JO

A

XII

I-3

2

01

9

ORIGINAL REASEARCH ARTICLE - CLINICAL STUDY

Clinical Evaluation The Therapeutic Effect Of Haridra (Curcuma longa Linn.) Churna On Dosha, Khadira (Acacia catechu Linn. f. Willd)

Churna On Dhatu And Aragvadha (Cassia fistula Linn.) Churna On Srotas In Shvitra

*Dr. Saroj Choudhary, **Dr. Rameshwar dudi , ***Dr. Sisir. Kumar Mandal, ****Prof. Pawan kumar Godatwar, *****Dr. S. K. Khandel

*Government Medical Officer (Raj. Govt.), Government Ayurved Aushdhalaya, Pachar, Jaipur, **Assistant Prof., Dept. of Basic Principles, Jyoti Vidyapeeth Women Univercity, Jaipur, ***Associate Professor, Dept. of Roga Nidana & Vikrti Vijnana, AIIA New

Delhi, ****Professor, *****Ex.Professor, Dept. of Roga Nidana & Vikrti Vijnana, NIA Jaipur

ABSTRACT

Keywords : Shvitra, Churna, Lakshana

Address of Correspondence: Dr. Saroj ChoudharyGovernment Medical Officer (Raj. Govt.), Government Ayurved Aushdhalaya, Pachar, Jaipur

Email ID : [email protected]

Contact No : 9413209943

How to Site the Article : Choudhary S, Dudi R, Mandal SK, Godatwar PK, Khandel SK, Clinical Evaluation The Therapeutic Effect Of Haridra (Curcuma longa Linn.) Churna On Dosha, Khadira (Acacia catechu Linn. f. Willd) Churna On Dhatu And Aragvadha (Cassia fistula Linn.) Churna On Srotas In Shvitra, JOA XIII-3, 2019; 5 - 13

This study was conducted to evaluation of the pathogenesis of shvitra. It was randomized controlled study on 60 number of patients and was divided into three groups named Group A, Group B, Group C. Haridra churna was given to Group A, dose of Haridra churna 6gm twice a day with Luke warm water. Khadira churna was given to Group B, dose of Khadira churna 6gm twice a day with Luke warm water. Aragvadha churna was given to Group C, dose of Aragvadha churna 6gm twice a day with Luke warm water. After completion the treatment it was assessed by the use of subjective criteria like as percentage of area, colour of affected area, colour of hair of affected part, number of patches, maximum size of patches, Mandalotpatti, Shwetavarnta, Rasa, Rakta, Mamsa & Meda vaha srota dushti lakshana, itiching by giving different grades for its severity and objective criteria was used Hb%, ESR, RBS, SGOT, SGPT, LDL. Separate questionnaire was prepared to assess the clinical features of ‘Shvitra’. Observations were recorded before & after treatment of 45 days with follow up at every 15 days. After treatment showed that the Rasa dusti lakshana 12.50%, 64.71% and 58.14%, Rakta dushti lakshana 12.50%, 55% and 68.57%, Mamsa dushti lakshana 0.00%, 14.29%

and 54.55% , Meda dushti lakshana 5.88%, 10.53% and 76.19% was reduced by respectively in Group A, B & C. Finally it was observed that group B was more effective than Grop A and C.


Choudhary S, Dudi R, Mandal SK, Godatwar PK, Khandel SK, Clinical Evaluation The Therapeutic Effect Of Haridra (Curcuma longa Linn.) Churna On Dosha, Khadira (Acacia catechu Linn. f. Willd) Churna On Dhatu And Aragvadha (Cassia fistula Linn.) Churna On Srotas In

Shvitra JOA XIII-3, 2019; 5 - 13

Introduction:

Ayurveda, the science of life uses natural resources in fulfilling the fundamental objectives i.e. Swasthya Rakshanam and Vyadhi Prashamanam. Skin is like mirror that reflects external and internal pathology, and thus helps in diagnosis of disease.

All the skin diseases in Ayurveda have been described under heading of Kushtha, which are further divided into Maha Kustha and Kshudra Kushtha. However Shvitra has not been counted among various types of Kushtha in Brihattrayi. Later on this has been included under types of Kushtha by various Acharyas. Though Shvitra is mentioned along with other types of Kushtha, but the difference between Shvitra and Kushtha is based on non-secretary and non-infectious nature of disease, involvement of Twaka only, peculiarity of Nidana, Asadhya Lakshana and chronicity.

According to Modern dermatology, Shvitra can be correlated with Vitiligo and Leucoderma.Vitiligo is a common disorder of unknown etiology even today[1].Worldwide prevalence of Vitiligo is observed as 1% of the world population[2]. Based on dermatological out patient record, it is estimated between 3-4% in India, although an incident as high as 8.8% has also been reported[3], irrespective of the races especially to dark skinned people.

There is no definite line of treatment is given in the classics but the Acharyas have described Shvitra in the chapter of Kushtha Chikitsa and mentioned that the treatment should be done like Kushtha. The pathogenesis of Shvitra is not found separately in texts except Harita Samhita. According to Harita Samhita the vitiation of Vata along with the Pitta Dosha spoil the Rakta Dhatu and create the spot of Pandura Varna that is called Shvitra. In this way the specific line of treatment is alone given by Acharya Harita[4]. Acharya Charaka has mentioned that Samshamana therapy can be administered to patient after Sodhana therapy in this disease[5].

Need Of Study:

All previous research works considered that disease must be treated for long time, means shvitra is a disease which takes much more time to get cure. So it is the need of today to find out the treatment which cures to the particular disease shvitra in reasonable period.

In Ayurveda the disease comprise of dosa dusya & srotas as internal factor but there variation of involvement may change the nature as well as treatment protocol of the disease. For example, in case of 'Atisara disease' physician should more concentrate about the involvement of srotas, unlikely for the dhatus (dusyas) or dosha. In various times it is also observed that different physician also choose the different line of treatment with success but their duration of complete remission or rate of cure are different. Samprapti vighatana is known as chikitsa. It may be anywhere of the chain but the time is also a major factor. Especially those which are chronic in nature. So comparative trial among the drugs which are acting on dosas, dhatus and srotas may give a clear-cut ratio of involvement of the internal factors (dosha, dusya & srotas) of a particular disease. Though there are no such drug which only have the particular property as dosha pratyanika etc, but after reviewing the most pointed effect over the particulars pathogenic elements, the above mentioned drugs have been chosen.

Aims and Objectives:

The current research project entitled “Clinical Evaluation The Therapeutic Effect Of Haridra (Curcuma longa Linn.) Churna On Dosha, Khadira (Acacia catechu Linn. f. Willd) Churna On Dhatu And Aragvadha (Cassia fistula Linn.) Churna On Srotas In Shvitra”was undertaken with following aims and objectives-

1. To prepare a treatment protocol for the shvitra.

2. To evaluate the involvement of the vitiated dosha, dhatu and srotas in the particular disease shvitra.

Materials & Methods:

Following materials and methods was employed for conducting the present research project-Ethical Approval- The present research work was




approved by IEC (Institute Ethical Commite) of National Institute of Ayurveda, Jaipur vide latter No.F10(5)/EC/2014/7276; dated 07.11.2014,before starting the clinical trial on patients of EHT.

1) Selection of cases:- The patients for the clinical study were selected from O.P.D. and I.P.D. of NIA Hospital, Roga Nidana Evam Vikrti Vijnana department. Selection was carried out on the basis of relevant history, signs, symptoms and laboratory investigations.

Grouping:- In this present study, total 66 patients were registered, 60 patients completed the trial while 02 patients from Group A , 01 patient from Group B and 03 patient from Group C Left Against Medical Advice (LAMA). Out of 66 patients, 60 patients were divided into 3 groups namely A, B & C

Group A: Haridra Powder 6gm twice a day with Luke warm water.

Group B: Khadira Powder 6gm twice a day with Luke warm water.

Group C: Aragvadha Powder 6gm twice a day with Luke warm water.

Total duration of Treatment was 45 days with the regular follow up in an interval of 15 days for observing any side effect of drugs. All the patients were advised to take light, easily digestible diet & to avoid incompatible food.

2) Inclusion Criteria:-

1. Patients were randomly selected irrespective of sex, religion, occupation, and economic status after due process of informed consent.

2. Patients presenting with symptom of shvitra were included in the study.

3) Exclusion Criteria:-

1. Uncooperative & immuno suppressive patients

2. The patient of Shvitra were excluded those are Asadhya in nature (as per classical text of Ayurveda}

3. Patients below 18 years and above 50 years

4. Patients suffering from major illness.

5. Pregnant Women

6. Patients with history of trauma & burn

Plan of Work:-The study was carried out as follows-

1) Detailed Performa: A special performa was prepared to maintain the records of all findings regarding the patients.

Laboratorial Investigation

The following laboratory criteria were used on investigation ground:

● Hematological – Hb% & ESR

● Biochemistry –RBS, SGOT, SGPT, LDL

Drug Schedule:-

Group A: 20 registered patients of Shvitra wad administered Haridra Powder 6gm twice a day with Luke warm water.

Group B: 20 registered patients of Shvitra wad administered Kadhira Powder 6gm twice a day with Luke warm water.

Group C: 20 registered patients of Shvitra wad administered Aragvadha Powder 6gm twice a day with Luke warm water.

Criteria for Assessment of Drug efficacy

Both subjective and objective parameters were taken into consideration for assessment of drug efficacy.

Subjective and Objective Assessment

More emphasis was given on subjective parameters like No. of Patches, Patches size, Colour of affected area, Kandu (Itching), Site of Involvement, Colour of hair in the affected area etc. which were classified into grades. The improvement in grade was recorded at different levels. The affected area was assessed by photography.

Grading of Shvitra patients with reference to different symptoms:-

Assessment criteria




Percentage of area

Number of Patches:

Percentage of area Score1% 12% 23% 34% 4

>4% 5

Number Of Patches Score1 12 23 34 4

>4 5

Size of Patches:

Colour of Patches:

Kandu (Itching):

Size Score1 cm 12 cm 23 cm 34 cm 4

>4 cm 5

Colour of area ScoreNormal Skin color 1

Red colour 2White to reddish 3

Red to whitish 4White 5

Scale ScoreNo itching 0Mild / Occasional itching 1Moderate (tolerable) infrequent 2Severe itching frequently 3Very severe itching disturbing sleep and other activities 4




Colour of hair in the affected part

Colour ScoreBlack 0Gray (Pinjara) colour 1Reddish 2White 3

The result was remarked as;

● Complete improvement- 100% relief

● Marked relief - Above 75% improvement

● Moderate relief - Above 50% Improvement

● Mild relief - Above 25% Improvement

● Minimal relief - Below 25% Improvement

● No relief - No improvement

Observation and Results:- The observation and Re-

sults have been made in the present work under the fol-lowing headings.1) Demographic Profile.

a) Demography of general profile - According to observed data Maximum patients were from the age Group of 18-30 yrs, female, service class, Hindu in religion, married, middle upper class etc.

b) Demography of clinical profile - Maximum patients (41.26%) were having >2 year of duration

Assessment of Therapy -

Table: I Effect Of Group A Drug Haridra (Curcuma Longa Linn.) Churna On Subjective Parameters

Subjective ParametersMean

Diff. Diff. % S.D. S.E. W P value ResultsBT AT

% of area 4.35 4.05 0.3 6.90 0.57 0.12 15 0.625 NS

Colour of Affected Area 5.00 4.5 0.5 10.00 1.05 0.23 10 0.125 NS

Itching 0.95 0.3 0.65 68.42 0.67 0.15 66 0.001 VS

colour of hair of affected part 1.35 1.25 0.1 7.41 0.30 0.06 3 0.500 NS

Number Of Patches 3.35 3 0.4 11.94 0.82 0.18 15 0.0625 NS

maxi.Size of patch 3.35 3 0.35 10.45 0.58 0.13 21 0.0313 S

Mandalotpatti 5.00 4.5 0.5 10.00 1.05 0.23 10 0.1250 NS

Shwetavarnta 5.00 4.5 0.5 10.00 1.05 0.23 10 0.1250 NS

Bahalata 0.2 0.2 0 0.00 0 0 - >0.05 NS

Rasavaha sroto dushti lakshana 1.6 1.4 0.2 12.50 0.52 0.11 6 0.2500 NS

Raktavaha sroto dushti lakshana 1.6 1.4 0.2 12.50 0.52 0.11 6 0.2500 NS

Mamsavaha sroto dushti lakshana 1.5 1.5 0 0.00 0 0 - >0.05 NS

Medavaha sroto dushti lakshana 1.7 1.68 0.1 5.88 0.44 0.1 1 >0.05 NS




Table: II Effect of Group B drug Khadira (Acacia catechu (Linn. f.) Willd churna on Subjective parameters

Table: III Effect of Group C drug Aragvadha( Cassia fistula Linn.) churna on Subjective parameters


Diff Diff % S.D. S.E. W P Value ResultsBT AT

% of area 3.45 1.7 1.75 50.72 1.019 0.22 210 <0.0001 VS

Colour of Affected Area 5 1.7 3.3 66.00 0.73 0.16 210 <0.0001 VS Itching 0.2 0.05 0.15 75.00 0.36 0.08 6 0.2500 NScolour of hair of affected part 1.05 0.55 0.5 47.62 0.68 0.15 36 0.0078 VSNumber Of Patches 3.3 2 1.6 48.48 1.14 0.25 171 <0.0001 VSmaxi.Size of patch 3.2 1.55 1.65 51.56 0.81 0.18 210 <0.0001 VSMandalotpatti 5 1.75 3.25 65.00 0.71 0.16 210 <0.0001 VSShwetavarnta 5 1.75 3.25 65.00 0.71 0.16 210 <0.0001 VSBahalata 0.3 0.3 0 0.00 0 0 --- >0.05 NSRasavaha sroto dushti lakshana 1.7 0.6 1.1 64.71 0.78 0.17 136 <0.0001 VSRaktavaha sroto dushti lakshana 1 0.45 0.55 55.00 0.51 0.11 11 <0.0001 VSMamsavaha sroto dushti lakshana 0.7 0.6 0.1 14.29 0.30 0.06 6 0.0313 SMedavaha sroto dushti lakshana 0.95 0.85 0.1 10.53 0.30 0.06 6 0.0002 VS


Diff Diff % S.D. S.E. W P Value Results

BT AT% of area 3.7 3.2 0.5 13.51 0.68 0.15 17 0.0078 VSColour of Affected Area 4.7 3.84 1.05 22.34 1.60 0.35 210 0.0234 SItching 0.35 0.2 0.15 42.86 0.36 0.08 51 0.2500 NScolour of hair of affected part 1.75 1.4 0.35 20.00 0.58 0.13 11 0.1250 NSNumber Of Patches 2.7 1 0.35 12.96 0.81 0.18 36 0.156 NSmaxi.Size of patch 3.35 2.8 0.55 16.42 0.88 0.19 210 0.0156 SMandalotpatti 4.7 3.84 1.05 22.34 1.60 0.35 71 0.0234 SShwetavarnta 4.7 3.84 1.05 22.34 1.60 0.35 6 0.0210 SBahalata 0.25 0.25 0 0.00 0 0 11 >0.05 NSRasavaha sroto dushti lakshana 2.15 0.9 1.25 58.14 0.71 0.16 121 <0.0001 VSRaktavaha sroto dushti lakshana 1.75 0.55 1.2 68.57 0.69 0.15 33 <0.0001 VSMamsavaha sroto dushti lakshana 0.55 0.25 0.3 54.55 0.47 0.10 11 0.0313 SMedavaha sroto dushti lakshana 1.05 0.25 0.8 76.19 0.69 0.15 4 0.0002 VS

Results of the Therapeutic Trial-

¾ Effect of trial drug Haridra (Curcuma longa Linn.) churna on subjective parameters showed that there was a statistically very significant improvement was found on Itching (P=0.001), statistically

significant improvement was found on maxi. Size of patch (P=0.0313). % of area (P=0.625), Colour of Affected Area (P=0.125), colour of hair of affected part (P=0.500), Number Of Patches (P=0.0625), Mandalot patti (P=0.1250), Shwetavarnta




(P=0.1250), Bahalata (P=>0.05), Rasa (P=0.2500), Rakta (P=0.2500), Mamsa (P=>0.05) & Medavaha sroto dushti lakshana (P=>0.05) considered statistically not quite significant.

¾ Effect of trial drug Khadira ( Acacia catechu (Linn. f.) Willd churna on subjective parameters showed that there was a statistically very significant improvement was found on % of area (P=<0.0001), Colour of Affected Area (P=<0.0001), colour of hair of affected part (P=0.0078), maxi.Size of patch (P=<0.0001), Number Of Patches (P=<0.0001), Mandalotpatti (P=<0.0001), Shwetavarnta (P=<0.0001), Rasa (P=<0.0001), Rakta (P=<0.0001), Medavaha sroto dushti lakshana (P=0.0002) and statistically significant improvement was found on Mamsa (P=0.0313). Itching (P=0.2500), & Bahalata (P=>0.05) considered statistically not quite significant.

¾ Effect of trial drug Aragvadha (Cassia fistula Linn.) churna on subjective parameters showed that there was a statistically very significant improvement was found on % of area (P=0.0078), Rasa (P=<0.0001), Rakta (P=<0.0001), Meda vaha sroto dushti lakshana (P=0.0002). Statistically significant improvement was found on Colour of Affected Area (P=0.0234), maxi. Size of patch (P=0.0156), Mandalotpatti (P=0.0234), Shwetavarnta (P=0.0210), and Mamsa (P=0.0313). Itching (P=0.2500), colour of hair of affected part (P= 0.1250), Number Of Patches (P= 0.156), & Bahalata (P=>0.05) considered statistically not

quite significant.

Comparison Of The Effects Of Therapy:

" The effect of therapies, Khadira churna proved more effective to control % of affected area, colour of affected area, colour of hair of affected part, number of patches, maximum size of patches, Mandalotpatti, Shwetavarnta.

" The effect of therapies, Aragvadha churna proved more effective to dhatu dushti lakshana i.e. Rasa, Rakta, Mamsa & Meda dushti.

" The effect of therapies, Haridra churna proved more effective on doshic clinical features like itching etc.

" Overall effect of the therapy on clinical features of Svitra reflect that Dhatu produshana pathological event is more prominent, followed by obstruction of micro channels (dhatu vahi Srotasamsi dushti), though doshas are considered as prime cause for any disease progression but in this particular disease Shvitra it is active up to the event of doshadushya samurcchana. After that some scattered clinical features like itching etc. may govern by morbid doshas and that may prevent though dosha shamaka Group, i.e. Group A- Haridra churna. Otherwise dhatu promoting drugs and drugs those are act through micro channels (Rasayana) having more dominant effect to cure the disease Shvitra. The study was conducted with short duration as a upashayatmaka trial, result just give a clue to make a treatment protocol that may able to cure the disease successfully within a reasonable time.

Patient Registration No.51057

Before Treatment After Treatment




Probable Mode Of Action Of Drug:

Effect On Dosha:

1) Haridra churna

Hence Shvitra is Tridoshaja vyadhi, Kapha dosha is the most dominant Dosha in shvitra. Haridra being Tikta and Katu Rasa, Katu Vipaka & Ushna Virya and Kapha & Pitta Shamaka . These properties facilitate to improve the doshic status, which is involved in shvitra i.e. chiefly morbid kapha. Apart from these it has also varnya, tvakadosha shamaka, vranapaha, kushtha nashaka properties. So, by guna prabhabha it directly acts in dosha and by dravya prabhava it indirectly helps in samprapti vighatana. Also Haridra consider as dosha pachana in context to Amadosha[6].

Effect On Dushya:

2) Khadira churna

Rasa, Rakta, Mamsa, Meda and Lasika are the dushyas of Shvitra. Tvaka and Lasika are related with Rasadhatu. Symptoms of Rasavriddha are similar to Kaphavriddha[7]. Langhana is mentioned for treatment of Rasa Dushti. By virtue of Tikta, Kashaya Rasa, and sheeta virya of Khadira, it corrects Pitta. Pitta, specially Pachaka Pitta helps in proper formation of Raktadhatu and thereby combating Rakta Dushti. Pachaka Pitta also controls other Pitta including Bhrajaka Pitta which is also vitiated in Shvitra. Tikta, Kashaya Rasa of Khadira which causes Lekhana of Pravrddha Malarupa Mamsa Dhatu and stop the production of Mala Rupa Kleda (Upahanti Kleda). But the foremost action of Khadira, it is a rasayana, it correct the vitiated dhatus (rasa & rakata etc.) and maintain the pure one. That is why Khadira consider as a best kushthagna drugs and mentioned abundantly in Kushtha chikitsa with different mode of application.

Effect On Srotas:

3) Aragvadha churna

Rasavaha, Raktavaha Srotasa gets vitiated in shvitra. Aaragvadh is having, Madhura rasa, Guru, Snigdha,

Mridu guna, Sheeta virya, Madhura Vipaka. So it helps in pacification of Vayu. Thus it rescues the normal activities of Srotas. Apart from these Aragvadha does Amashodhana which removes Sanga from Srotasa and does Srotomukha Visodhana. Due to this Vata becomes channelized; remove Avarana and helps in Samprapti Vighatana.

Effect On Vyadhi:

Haridra, Khadira & Aragvadha has Kushthaghna property. So it directly effects on Shvitra. According to Ayurveda doctrines, the assimilation of Dosha & Dushya leads to formation of disease only when the Agni is reduced and quality of Dhatu become deteriorated (Shithilakarana). Shvitra is the disease which develops when Rakta, Mamsa, Meda, Lasika become Shithila. Katu Rasa of Khidra maintains the Agni and improves the quality of Rasadi Dhatu and gives strength to them and produces Sthairya. Khadira have Kasaya Rasa which does Ropana & Samdhanakara Karma, thus prevent the disease formation.

Conclusion

¾ Group A drug Haridra (Curcuma longa Linn.) churna is effective in the signs & symptoms like – Itching & maxi.Size of patch.

¾ Group B drug Khadir (Acacia catechu (Linn. f.) Willd churna is effective in % of area, Colour of Affected Area, colour of hair of affected part, maxi.Size of patch, Number Of Patches, Mandalotpatti, Shwetavarnta, Srotho dusti lakshna of Rasa,Rakta, mamsa, medavaha srotas and not effective in Bahalata , Itching.

¾ Group C drug Aaragvadha (Cassia fistula Linn.) churna is effective in % of area, Colour of Affected Area, maxi.Size of patch, Mandalotpatti, Shwetavarnta, Srotho dusti lakshna of Rasa, Rakta, mamsa, meda srotas and not effective in Number Of Patches, colour of hair of affected part, Bahalata, Itching.

¾ The result of these therapies shows that statistically




highly significant result in Group B who were treated with Khadira Churna. Thus it reflects that dhatus are deeply involved in present study. It can be concluded that in chronic diseases dhatu prasadana chikitsa is more effective than dosha prashamana Shamana therapy etc.

¾ On srota dushti lakshana Group C shows better result which was treated with Aaragvadha Churna. Aaragvadha Churna bring back the normalcy of srotas by push out the malas from involved srotas .

¾ Aaragvadha Churna and Khadira Churna show significant result on the clinical features % of area, colour of affected area, Mandoltpatti, Shweta Varnata, and rasa, rakta. Mamsa, Medavaha srota dushti lakshana.

¾ On itching the trial drug Haridra Churna shows significant result.

¾ No trial drug is not effective in Laboratory parameters like- Hb%, ESR., RBS, SGOT,SGOT,LDL

¾ No side/toxic effects of drugs were noted. So, all the trial drugs are safe.

¾ All the trial drugs are cost effective and easily available.

References

1. Robbins, Cotran, Kumar ed. Pathologic basis of disease, 27nth Chapter, W.B.Saunders company.pp.1274.

2. John A.A.Hunter ed, Davidson’s principles and practice of medicine, 19th ed, 2002, 21st chapter, Churchill Livingstone. pp 1086, 1087.

3. R.G.Valia ed. Text book and atlas of dermatology 22nd chapter 1st ed, 1994, Bhalani publishing house Bombay, pp. 518,519.

4. Harita samhita, ‘Haree hindi vyakhya’ edited by pandit Harihar Prasad Tripathi, Chaukhambha Krishnadas acadamy, Varanasi print, 2009. Tritiya Sthana 39/50,51.

5. Aacharya Agnivesha, Charaka Samhita edited by Vaidya Yadavaji Trikamji Chaukhambha Subharati prakashan, Varanasi reprint 2011, Chikitsasthana 7/162, pp. 458.

6. P.V. Sharma, Dravyaguna Vidnyana, Vol II, Chaukhamba Bharti, Varanasi (India), 2006; p.162-164.

7. Dr. Brahmanand Tripathi, Astanga Hridayam, Chaukhamba Sanskrit pratishthan, Delhi 2007, sutrasthana 11/8

lkjka'k%

;g v/;;u fÜo= ds j¨xtuu ds ewY;kadu ds fy, fd;k x;k FkkA ;g 60 j¨fx;ä ij ;k–fPNd :i ls fu;af=r v/;;u Fkk vkSj bls

lewg ,] lewg ch] lewg lh uke ds rhu lewgä esa foÒkftr fd;k x;k Fkk] gfjæk pw.kZ d¨ xeZ ikuh ds lkFk fnu esa n¨ ckj 6gm dh ek=k

esa lewg , d¨ fn;k x;k Fkk] [kfnj pw.kZ d¨ xeZ ikuh ds lkFk fnu esa n¨ ckj 6gm dh ek=k lewg ch d¨ fn;k x;k Fkk] vkjXo/k pw.kZ d¨

xeZ ikuh ds lkFk fnu esa n¨ ckj 6gm dh ek=k lewg x d¨ fn;k x;k FkkA mipkj iwjk güs ds ckn O;fäijd ekunaM dk mi;¨x fd;k

x;k Fkk tSls fd ÁÒkfor {ks= dk Áfr'kr] ÁÒkfor {ks= dk jax] ÁÒkfor Òkx ds ckyä dk jax] iSp dh la[;k] iSp dk vf/kdre vkdkj]

eaMy¨RifÙk] Üosro.kZ] jl] jä] ekal vkSj esn¨ og lz¨rks nqf"V y{k.k] bldh xaÒhjrk vkSj oLrqfu"B ekunaMä ds fy, vyx&vyx xzsM nsdj

bls ,pch%] Ã,lvkj] vkjch,l] ,lthvksVh] ,lthihVh] ,yMh,y dk mi;¨x fd;k x;k FkkA Á'ukoyh dh uSnkfud fo'ks"krkvksa dk

vkdyu djus ds fy, vyx Á'ukoyh rS;kj dh xÃ FkhA igys voy¨du fd, x, Fks vkSj gj 15 fnuä ij Q‚y¨vi ds lkFk 45 fnuä

ds mipkj ds ckn irk pyk fd jl nqf"V y{k.k 12.50%] 64.71% vkSj 58.14%] jä nqf"V y{k.k 12.50%] 55% vkSj 68.57%] ekal

nqf"V y{k.k 0.00%] 14.29% vkSj 54.55% ] esn¨ nqf"V y{k.k 5.88%] 10.53% vkSj 76.19% lewg ,] ch vkSj lh es Øe'k% ÄVk FkkA

Documents

ORIGINAL REASEARCH ARTICLE - CLINICAL STUDY · 2020. 1. 17. · yurveda O Ayurveda J 5 JOA journalofayurveda.in ISSN No:2321-0435 JOA XIII-3 2019 ORIGINAL REASEARCH ARTICLE - CLINICAL