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MEETING ABSTRACT Open Access Optimalization of recovery, regeneration and rehabilitation Jaroslav Novak 1 , Václav Zeman 1* , Martin Matoulek 2 , Ondřej Topolčan 1 , Śárka Svobodova 2 , Jaroslav Racek 1 , Judita Kinkorova 3 From EPMA-World Congress 2013 Brussels, Belgium. 20-21 September 201 Scientific objectives Physically active subjects have superior aerobic perfor- mance and effort tolerance compared to the less active subjects. There was observed association between high exercise capacity and low mortality. The protective effect of physical activity and exercise capacity preventing the progression of diseases, and thus on premature death, could be one of explanations for this association. Most of this protection is assumed to result from the beneficial effects of physical exercise on blood lipids, blood pressure, glucose metabolism, vascular function, autonomic tone, blood coagulation, and inflammation. Technological approaches and results interpretation We have currently initiated the examination of metabolic parameters, hormones, inflammatory parameters, growth angiogenic parameters and bone metabolism parameters in 4 groups of individuals: active sportsmen, sportsmen involved in sports with extreme load (i.e. ultra-marathon performance - e.g. 100 km running in 24 hrs, intermediate and long triathlons, long-distance swimming, etc.), in patients with cancer diseases and patients with cardiovas- cular diseases, who were individually recommended appropriate form of physical activity as a part of complex therapy. Outlook and expert recommendations The aim of this study was to compare the differences of the monitored parameter between the different groups of patients that are significantly different from health condition and from the level of physical activity. The final goal is to find the optimal biomarkers potentially useful as an indicator of optimal recovery course and rehabilitation after physical activity load single evalua- tion and long term monitoring. Acknowledgements This study was supported by the project Ministry of Education ED2.1.00/ 03.0040 and by the project of Ministry of Health, Czech Republic for conceptual development of research organization 00669806 - Faculty Hospital in Pilsen, Czech Republic. Authorsdetails 1 Medical Faculty Pilsen and Faculty Hospital Pilsen, Charles University Prague, Czech Republic. 2 1 st Medical Faculty Prague and General Faculty Hospital Prague, Charles University, Prague, Czech Republic. 3 Technology Centre Academy of Sciences, Czech Republic. Published: 11 February 2014 doi:10.1186/1878-5085-5-S1-A152 Cite this article as: Novak et al.: Optimalization of recovery, regeneration and rehabilitation. EPMA Journal 2014 5(Suppl 1):A152. Submit your next manuscript to BioMed Central and take full advantage of: Convenient online submission Thorough peer review No space constraints or color figure charges Immediate publication on acceptance Inclusion in PubMed, CAS, Scopus and Google Scholar Research which is freely available for redistribution Submit your manuscript at www.biomedcentral.com/submit * Correspondence: [email protected] 1 Medical Faculty Pilsen and Faculty Hospital Pilsen, Charles University Prague, Czech Republic Full list of author information is available at the end of the article Novak et al. EPMA Journal 2014, 5(Suppl 1):A152 http://www.epmajournal.com/content/5/S1/A152 © 2014 Novak et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. 3

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MEETING ABSTRACT Open Access

Optimalization of recovery, regeneration andrehabilitationJaroslav Novak1, Václav Zeman1*, Martin Matoulek2, Ondřej Topolčan1, Śárka Svobodova2, Jaroslav Racek1,Judita Kinkorova3

From EPMA-World Congress 2013Brussels, Belgium. 20-21 September 201

Scientific objectivesPhysically active subjects have superior aerobic perfor-mance and effort tolerance compared to the less activesubjects. There was observed association between highexercise capacity and low mortality. The protective effectof physical activity and exercise capacity preventing theprogression of diseases, and thus on premature death,could be one of explanations for this association. Most ofthis protection is assumed to result from the beneficialeffects of physical exercise on blood lipids, blood pressure,glucose metabolism, vascular function, autonomic tone,blood coagulation, and inflammation.

Technological approaches and resultsinterpretationWe have currently initiated the examination of metabolicparameters, hormones, inflammatory parameters, growthangiogenic parameters and bone metabolism parametersin 4 groups of individuals: active sportsmen, sportsmeninvolved in sports with extreme load (i.e. ultra-marathonperformance - e.g. 100 km running in 24 hrs, intermediateand long triathlons, long-distance swimming, etc.), inpatients with cancer diseases and patients with cardiovas-cular diseases, who were individually recommendedappropriate form of physical activity as a part of complextherapy.

Outlook and expert recommendationsThe aim of this study was to compare the differences ofthe monitored parameter between the different groupsof patients that are significantly different from healthcondition and from the level of physical activity. The

final goal is to find the optimal biomarkers potentiallyuseful as an indicator of optimal recovery course andrehabilitation after physical activity load – single evalua-tion and long term monitoring.

AcknowledgementsThis study was supported by the project Ministry of Education ED2.1.00/03.0040 and by the project of Ministry of Health, Czech Republic forconceptual development of research organization 00669806 - FacultyHospital in Pilsen, Czech Republic.

Authors’ details1Medical Faculty Pilsen and Faculty Hospital Pilsen, Charles University Prague,Czech Republic. 21st Medical Faculty Prague and General Faculty HospitalPrague, Charles University, Prague, Czech Republic. 3Technology CentreAcademy of Sciences, Czech Republic.

Published: 11 February 2014

doi:10.1186/1878-5085-5-S1-A152Cite this article as: Novak et al.: Optimalization of recovery,regeneration and rehabilitation. EPMA Journal 2014 5(Suppl 1):A152.

Submit your next manuscript to BioMed Centraland take full advantage of:

• Convenient online submission

• Thorough peer review

• No space constraints or color figure charges

• Immediate publication on acceptance

• Inclusion in PubMed, CAS, Scopus and Google Scholar

• Research which is freely available for redistribution

Submit your manuscript at www.biomedcentral.com/submit

* Correspondence: [email protected] Faculty Pilsen and Faculty Hospital Pilsen, Charles University Prague,Czech RepublicFull list of author information is available at the end of the article

Novak et al. EPMA Journal 2014, 5(Suppl 1):A152http://www.epmajournal.com/content/5/S1/A152

© 2014 Novak et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative CommonsAttribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction inany medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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