And, most of the morphine equivalents dispensed arereceived by COT patients on higher dose regimens, thereby becoming available for diversion for non-medical use.

0%

23%

45%

68%

90%

Chronic Pain Patients Using Opioids Long-term All Other Pain Patients

Percent total morphine equivalents (ME) dispensed in 2008

60 % of total ME dispensed

27 % of total ME dispensed

13 % of total ME dispensed

(Acute & Cancer Pain)

Average daily dose > 50 mg.

Average daily dose < 50 mg.