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YG - 150910 Opening New Dimensions In Changing Times Yannick Gardin, DVM, Director of Science and Innovation in Biology Ceva Animal Health, Libourne, France Ceva Poultry Vaccinology Summit March 14th – 16th, 2016 – Barcelona, Spain

Opening New Dimensions In Changing Times - … · Opening New Dimensions. In. Changing Times. Yannick Gardin, ... way to adapt to new viruses or ... The problem of trading regulations

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YG - 150910

Opening New DimensionsIn

Changing Times

Yannick Gardin, DVM,Director of Science and Innovation in Biology

Ceva Animal Health, Libourne, France

Ceva Poultry Vaccinology SummitMarch 14th – 16th, 2016 – Barcelona, Spain

YG - 150910

Not all the days are sunny !

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Not all the days are sunny !

YG - 150910HAPPY LIFE

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HAPPY LIFE

Not all the days are sunny !

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HAPPY LIFE

Quality

Not all the days are sunny !

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HAPPY LIFE

Quality

Profitability

Not all the days are sunny !

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Not all the days are sunny !

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Not all the days are sunny !

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DISEASE

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DISEASE

Not all the days are sunny !

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Quality

DISEASE

Not all the days are sunny !

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Quality

Profitability

DISEASE

Not all the days are sunny !

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ANIMAL WELFARE

Quality

Profitability

Not all the days are sunny !

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Can you really support an industry

that kills animals by millions

and createsantibiotic resistance ?

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Can you really support an industry

that kills animals by millions

and createsantibiotic resistance ?

we

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What can be done ?

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What can be done ?

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Pathogens came first !

What can be done ?

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Pathogens came first !

What can be done ?

Prevention

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Pathogens came first !

What can be done ?

Prevention Treatment

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Invest in Research & Innovation

What can be done ?

Prevention Treatment1

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Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Identification of pathogens

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Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Identification of pathogensKnowledge on epidemiology

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Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Identification of pathogensKnowledge on epidemiologyUnderstanding the mechanisms of:

- infection- pathogenicity- protection

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Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Identification of pathogensKnowledge on epidemiologyUnderstanding the mechanisms of:

- infection- pathogenicity- protection

More tools to improve or intervene on

YG - 150910

Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Identification of pathogensKnowledge on epidemiologyUnderstanding the mechanisms of:

- infection- pathogenicity- protection

More tools to improve or intervene on

YG - 150910

Invest in Research & Innovation

What can be done ?

Prevention Treatment1

Developp new concepts / new tools / new models:- Prevent- Protect- Treat

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

Challenge

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

ChallengeINFECTION

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

ChallengeINFECTION

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING

ChallengeINFECTION

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING

ChallengeINFECTION

SPREADING

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING

ChallengeINFECTION

SPREADING

With vaccination

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING SPREADING

ChallengeINFECTION

With vaccination

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING SPREADING

ChallengeINFECTION

With vaccination

YG - 150910

Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING SPREADING

ChallengeINFECTION

With vaccination

YG - 150910

Ask more from Vaccines

What can be done ?

Prevention Treatment2

DISEASE

SHEDDING SPREADING

ChallengeINFECTION

With vaccination

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

With vaccinationLess sheddingLess spreading

Less breaksBetter control

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

IBDrHVT-VP2 Immune-Complex

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

IBDrHVT-VP2 Immune-Complex

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Ask more from Vaccines

What can be done ?

Prevention Treatment2

IBDrHVT-VP2 Immune-Complex

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

Vaccination prevents eradication !

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

CHICKEN STATUS HI TEST NP ELISANOT VACCINATED NOT INFECTED - -NOT VACCINATED INFECTED + +VACCINATED NOT INFECTED + -VACCINATED INFECTED + +

The "DIVA strategy

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

CHICKEN STATUS HI TEST NP ELISANOT VACCINATED NOT INFECTED - -NOT VACCINATED INFECTED + +VACCINATED NOT INFECTED + -VACCINATED INFECTED + +

The "DIVA strategy

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

Routine vaccination against Avian Influenza

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Get rid of the dogmas

What can be done ?

Prevention Treatment3

Routine vaccination against Avian Influenza

WHY NOT ?

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Update regulations / Licensing

What can be done ?

Prevention Treatment4

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Update regulations / Licensing

What can be done ?

Prevention Treatment4

Any new vaccine = 4-5 years of registration

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Platform vaccines

The Platform / Cassette concept

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Platform vaccines

The Platform / Cassette concept

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Platform vaccines

The Platform / Cassette concept

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Platform vaccines

The Platform / Cassette concept

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Platform vaccines

The Platform / Cassette concept“Simple, easy and fast

way to adapt to new viruses or variations of the targeted

challenge virus for Customized Vaccines”

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USDA Memorandum 800.213

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USDA Memorandum 800.213

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USDA Memorandum 800.213

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Update regulations / Trading

What can be done ?

Prevention Treatment5

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The problem of trading regulations

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The problem of trading regulations

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The problem of trading regulations

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The problem of trading regulations

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The problem of trading regulations

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Conclusions

Today, we have more opportunities, concepts and toolsthan ever to:

- answer the requests from the consumers andthe society

- develop new and better solutions for preventionand treatment of infectious diseases

The obvious needs are for investments, changes in ourmindsets and update of regulations

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THANK YOUFOR YOUR ATTENTION