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ASTMH is an international society committed to equity and global impact through the treatment and prevention of tropical infectious diseases. Our diverse membership comes from more than 115 countries... we are committed to the open exchange of ideas, freedom of thought and expression, and productive scientific debate... open and diverse environment that is built on dignity and mutual respect for all... free of discrimination based on personal attributes including but not limited to ethnicity, color, national origin, age, religion, socioeconomic status, disability, sexual orientation, gender, and gender identity or expression. ASTMH is an international society committed to equity and global impact through the treatment and prevention of tropical infectious diseases. Our diverse membership comes from more than 115 countries... we are committed to the open exchange of ideas, freedom of thought and expression, and productive scientific debate... open and diverse environment that is built on dignity and mutual respect for all... free of discrimination based on personal attributes including but not limited to ethnicity, color, national origin, age, religion, socioeconomic status, disability, sexual orientation, gender, and gender identity or expression. ASTMH is an international society committed to equity and global impact through the treatment and prevention of tropical infectious diseases. Our diverse ANNUAL MEETING LATE-BREAKER ABSTRACTS PRESENTATION SCHEDULE November 20–24, 2019 | astmh.org | ajtmh.org | #TropMed19 #IamTropMed GAYLORD NATIONAL RESORT AND CONVENTION CENTER NATIONAL HARBOR, MARYLAND, USA SIXTY-EIGHTH

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Page 1: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

ASTMH is an international society committed to equity and global impact through

the treatment and prevention of tropical infectious diseases. Our diverse

membership comes from more than 115 countries... we are committed to the open

exchange of ideas, freedom of thought and expression, and productive scientific

debate... open and diverse environment that is built on dignity and mutual

respect for all... free of discrimination based on personal attributes including

but not limited to ethnicity, color, national origin, age, religion, socioeconomic

status, disability, sexual orientation, gender, and gender identity or expression.

ASTMH is an international society committed to equity and global impact through

the treatment and prevention of tropical infectious diseases. Our diverse

membership comes from more than 115 countries... we are committed to the open

exchange of ideas, freedom of thought and expression, and productive scientific

debate... open and diverse environment that is built on dignity and mutual

respect for all... free of discrimination based on personal attributes including

but not limited to ethnicity, color, national origin, age, religion, socioeconomic

status, disability, sexual orientation, gender, and gender identity or expression.

ASTMH is an international society committed to equity and global impact through

the treatment and prevention of tropical infectious diseases. Our diverse

membership comes from more than 115 countries... we are committed to the open

exchange of ideas, freedom of thought and expression, and productive scientific

debate... open and diverse environment that is built on dignity and mutual

respect for all... free of discrimination based on personal attributes including

but not limited to ethnicity, color, national origin, age, religion, socioeconomic

status, disability, sexual orientation, gender, and gender identity or expression.

ANNUAL MEETING

LATE-BREAKER ABSTRACTS PRESENTATION SCHEDULE

November 20–24, 2019 | astmh.org | ajtmh.org | #TropMed19 #IamTropMed

GAYLORD NATIONAL RESORT AND CONVENTION CENTER NATIONAL HARBOR, MARYLAND, USA

SIXTY-EIGHTH

Page 2: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

1

Table of Contents Page Number

Oral Presentations

Late Breaker Abstract Session 27

Late Breakers in Clinical and Applied Sciences

(Abstract #LB-5170 through LB-5176) ............................................................2

Oral Presentations

Late Breaker Abstract Session 79

Late Breakers in Basic Sciences

(Abstract #LB-5352 through LB-5358) ............................................................4

Oral Presentations

Late Breaker Abstract Session 133

Late Breakers in Malaria

(Abstract #LB-5536 through LB-5542) ............................................................6

Poster Session 26

Poster Session A

Late Breakers in Basic Sciences

(Abstract #LB-5000 through LB-5069) ............................................................8

Poster Session 26

Poster Session A

Late Breakers in Clinical and Applied Sciences

(Abstract #LB-5070 through LB-5169) ............................................................17

Poster Session 77

Poster Session B

Late Breakers in Basic Sciences

(Abstract #LB-5177 through LB-5245) ............................................................32

Poster Session 77

Poster Session B

Late Breakers in Clinical and Applied Sciences

(Abstract #LB-5246 through LB-5351) ............................................................42

Poster Session 131

Poster Session C

Late Breakers in Basic Sciences

(Abstract #LB-5359 through LB-5430) ............................................................58

Poster Session 131

Poster Session C

Late Breakers in Clinical and Applied Sciences

(Abstract #LB-5431 through LB-5535) ............................................................68

Presenter Index……………………………………………………………… .....................................83

Page 3: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

2

Late-Breaker Abstract Session 27

Late-Breakers in Clinical and Applied Sciences

Oral Presentations

National Harbor 3 (National Harbor Level)

Thursday, November 21, 12:15 p.m. - 1:30 p.m.

CHAIR

Miguel M. Cabada

University of Texas Medical Branch, Galveston, TX, United States

Noreen A. Hynes

Johns Hopkins School of Medicine, Baltimore, MD, United States

Jason D. Maguire

Pfizer, White Plains, NY, United States

12:15 p.m.

LB-5170

Effectiveness of Typhoid Conjugate Vaccine

against blood culture

confirmed Salmonella Typhi in an epicenter of

XDR Typhoid outbreak in Pakistan

Mohammad T. Yousafzai1, Farah N. Qamar1,

Sultan Karim1, Amber Kashif1, Hina Memon1, Ikram

Ullah Ujhan2 1The Aga Khan University, Karachi, Karachi,

Pakistan, 2Liaquat University of Medical and Health

Sciences, Hyderabad, Pakistan

12:25 p.m.

LB-5171

Clinical Development of TY014, a Therapeutic

Monoclonal Antibody Against Yellow Fever

Justin Han Jia Ng1, Debbie Lee1, Yok Hian Chionh1,

Eugenia Ong2, Yadunanda Budigi1, Eng Eong Ooi3,

Jenny Guek Hong Low4 1Tychan Pte Ltd, Singapore, Singapore, 2ViREMiCS,

Singapore, Singapore, 3Duke-NUS Medical School,

Singapore, Singapore, 4Department of Infectious

Disease, Singapore General Hospital, Singapore,

Singapore

12:35 p.m.

LB-5172

Antibody Persistence and the Immunologic

Response to Booster Vaccination with Live

Attenuated SA 14-14-2 Japanese Encephalitis

Vaccine

K. Zaman1, Md. Yunus1, Asma Binte Aziz1, Jodi

Feser2, Jessica Mooney2, Yuxia Tang2, Stefan

Fernandez3, Butsaya Thaisomboonsuk3, Lei Zhang4,

Kathleen M. Neuzil5, G. William Letson2, Anthony A.

Marfin2 1International Centre for Diarrhoeal Disease

Research, Bangladesh, Dhaka, Bangladesh, 2PATH,

Seattle, WA, United States, 3Armed Forces Research

Institute of Medical Sciences, Bangkok,

Thailand, 4Chengdu Institute of Biological Products,

Chengdu, China, 5Center for Vaccine Development

and Global Health, University of Maryland School of

Medicine, Baltimore, MD, United States

12:45 p.m.

LB-5173

Nifurtimox treatment in children with acute or

chronic Chagas disease: outcome at 1 year

after end of treatment - the Phase 3 CHICO

results

Jaime Altcheh

Hospital de Niños Dr. Ricardo Gutiérrez, Buenos

Aires, Argentina

Page 4: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

3

Late-Breaker Abstract Session 27

Late-Breakers in Clinical and Applied Sciences

Oral Presentations

National Harbor 3 (National Harbor Level)

Thursday, November 21, 12:15 p.m. - 1:30 p.m.

12:55 p.m.

LB-5174

Returning to pre-outbreak behaviors 6 months

post vaccination - A comparison in participants

vaccinated against Ebolavirus in an on-going

outbreak and a completed outbreak

Nicole A. Hoff1, Anna Bratcher1, Patrick Mukadi2,

Steve Ahuka2, Michel Kabamba3, Kamy Musene4,

Megan Halbrook1, Camille Dzogong4, Guillaume

Ngoie Mwamba3, J. Daniel Kelly5, Jean Paul

Kompany2, Merly Tambu2, Emile Okitolonda-

Wemakoy4, Benoit Kebela-Ilunga6, Jean-Jacques

Muyembe-Tamfum2, Anne W. Rimoin1 1UCLA Fielding School of Public Health, Los Angeles,

CA, United States, 2National Institute of Biomedical

Research, Kinshasa, Congo, Democratic Republic of

the, 3National Expanded Programme for

Immunization, Kinshasa, Congo, Democratic

Republic of the, 4Kinshasa School of Public Health,

Kinshasa, Congo, Democratic Republic of

the, 5School of Medicine, University of California, San

Francisco, San Francisco, CA, United

States, 6Direction of Disease Control, Ministry of

Health, Kinshasa, Congo, Democratic Republic of the

1:05 p.m.

LB-5175

Acute Febrile Illness and Antibiotic Treatment

in a Pediatric Cohort in Vellore, India

Arun S. Karthikeyan, Manikandan Srinivasan,

Chella Sindhu Kulandaipalayam Natarajan,

Karthikeyan Ramanujam, Venkata Raghava Mohan,

Jacob John, Gagandeep Kang

Christian Medical College, Vellore, India, Vellore,

India

1:15 p.m.

LB-5176

Does it matter where my neighbor poops? -

Community-level impacts of sanitation access

on maternal and neonatal health

Brittany L. Kmush1, Bhaneet Walia1, Anushruta

Neupane1, Carolina Frances1, Idris A. Mohamed1,

Mahwish Iqbal2, David Larsen1 1Syracuse University, Syracuse, NY, United

States, 2SUNY Upstate Medical University, Syracuse,

NY, United States

Page 5: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

4

Late-Breaker Abstract Session 79

Late-Breakers in Basic Sciences

Oral Presentations

National Harbor 3 (National Harbor Level)

Friday, November 22, 12:15 p.m. - 1:30 p.m.

CHAIR

Naomi Forrester

University of Texas Medical Branch, Galveston, TX, United States

Rebekah Kading

Colorado State University, Fort Collins, CO, United States

12:15 p.m.

LB-5352

Cachexia is a cost of long-term reliance on an

IL-1 driven tolerance strategy in T.

gondii infected mice

Sarah E. Ewald, Stephanie Melchor, Jessica Hatter

University of Virginia, Charlottesville, VA, United

States

12:25 p.m.

LB-5353

Transmission of arboviruses by mosquito

vectors to live vertebrate hosts is

underestimated by in vitro assays

Andrea Gloria-Soria, Doug Brackney, Philip

Armstrong

The Connecticut Agricultural Experiment Station,

New Haven, CT, United States

12:35 p.m.

LB-5354

Host Nutritional Status Affects Alphavirus

Virulence, Transmission, and Evolution

James Weger-Lucarelli1, Lucia Carrau2, Laura

Levi2, Veronica Rezelj2, Thomas Vallet2, Marco

Vignuzzi2 1Virginia Tech University, Blacksburg, VA, United

States, 2Institut Pasteur, Paris, France

12:45 p.m.

LB-5355

A bacterium against the Tiger: first evidence of

the potential of Aedes albopictus males with

manipulated Wolbachia infection to suppress

wild populations in European urban areas

Alessandra della Torre1, Beniamino Caputo1,

Riccardo Moretti2, Mattia Manica3, Paola Serini1,

Elena Lampazzi2, Marco Bonanni1, Giulia Fabbri2,

Giulia Lombardi2, Sonia Fidati1, Verena Pichler1,

Maurizio Calvitti2 1University of Rome SAPIENZA, Rome, Italy, 2Italian

National Agency for New Technologies, Energy and

Sustainable Economic Development, ENEA, Rome,

Italy, 3Fondazione Edmund Mach, San Michele

all'Adige, Trento, Italy

12:55 p.m.

LB-5356

Spondweni virus causes fetal harm in a mouse

model of vertical transmission and is

transmitted by Aedes aegypti mosquitoes

Anna S. Jaeger1, Andrea M. Weiler2, Ryan V.

Moriarty2, Sierra L. Rybarczyk2, Shelby L. O’Connor2,

David H. O’Connor2, Davis M. Seelig1, Thomas C.

Friedrich2, Matthew T. Aliota1 1University of Minnesota, Saint Paul, MN, United

States, 2University of Wisconsin-Madison, Madison,

WI, United States

Page 6: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

5

Late-Breaker Abstract Session 79

Late-Breakers in Basic Sciences

Oral Presentations

National Harbor 3 (National Harbor Level)

Friday, November 22, 12:15 p.m. - 1:30 p.m.

1:05 p.m.

LB-5357

Chikungunya Infection in Cerebral Organoids:

The Consequences of Neuroinvasive Disease in

Normal and Neurodegenerative Hosts

Kelli L. Barr, Emily M. Schultz, Tyanthony J. Jones,

Bernd Zechmann, Dana D. Dean, Hannah L. Clamp

Baylor University, Waco, TX, United States

1:15 p.m.

LB-5358

Blood feeding by arthropod vectors induces

heme oxygenase-1 in the skin controlling

inflammation and promoting tolerance to

disease

Thiago Soares de Souza Vieira1, Eva Iniguez2,

Tiago Donatelli Serafim2, Waldionne Castro2, Subir

Karmakar3, Ranadhir Dey3, Maria Disotuar1, Tales

Vicari Pascini4, Pedro Amado Cecilio1, Joshua

Lacsina1, Claudio Meneses1, Bianca Nagata5, Silvia

Cardoso6, Daniel Sonenshine1, Ian Moore7, Valeria M.

Borges8, Miguel P. Soares6, Hira L. Nakhasi3, Fabiano

Oliveira1, Jesus G. Valenzuela1, Shaden Kamhawi1 1Vector Molecular Biology Section, Laboratory of

Malaria and Vector Research, National Institute of

Allergy and Infectious Diseases, National Institutes

of Health, Rockville, MD, United States, 2Vector

Molecular Biology Section, Laboratory of Malaria and

Vector Research, National Institute of Allergy and

Infectious Diseases, National Institutes of Health,

Rockville, MD, United States, 3Laboratory of

Emerging Pathogens, Division of Emerging and

Transfusion Transmitted Diseases, Center for

Biologics Evaluation and Research, Food and Drug

Administration, Silver Spring, MD, United

States, 4Molecular Parasitology and Entomology Unit,

Laboratory of Malaria and Vector Research, National

Institute of Allergy and Infectious Diseases, National

Institutes of Health, Rockville, MD, United States,

Rockville, MD, United States, 5Infectious Disease

Pathogenesis Section, Laboratory of Malaria and

Vector Research, National Institute of Allergy and

Infectious Diseases, National Institutes of Health,

Rockville, MD, United States, Rockville, MD, United

States, 6Instituto Gulbenkian de Ciência, Oeiras,

Portugal, 7Infectious Disease Pathogenesis Section,

Laboratory of Malaria and Vector Research, National

Institute of Allergy and Infectious Diseases, National

Institutes of Health, Rockville, MD, United

States, 8Gonçalo Moniz Institute, Oswaldo Cruz

Foundation, Salvador, Brazil

Page 7: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

6

Late-Breaker Abstract Session 133

Late-Breakers in Malaria

Oral Presentations National Harbor 3 (National Harbor Level)

Saturday, November 23, 12:15 p.m. - 1:30 p.m.

CHAIR

Urszula Krzych

Walter Reed Army Institute of Research, Silver Spring, MD, United States

12:15 p.m.

LB-5536

Red Flag or False Alarm? Molecular markers of

Plasmodium falciparumartemisinin resistance

in Papua New Guinea

Alyssa E. Barry1, Dulcie Lautu2, Zahra Razook2,

Tamarah Koleala3, Elma Nate3, Manuel Hetzel4, Ivo

Mueller5, Leo Makita6, Moses Laman3, Leanne

Robinson7 1Deakin University, Geelong, Australia, 2Walter and

Eliza Hall Institute, Melbourne, Australia, 3Papua New

Guinea Institute of Medical Research, Madang, Papua

New Guinea, 4Swiss Tropical and Public Health

Institute, Basel, Switzerland, 5Walter and Eliza Hall

Institute of Medical Research, Melbourne,

Australia, 6National Department of Health, Port

Moresby, Papua New Guinea, 7Burnet Institute,

Melbourne, Australia

12:25 p.m.

LB-5537

Genetic mapping of fitness determinants across

the malaria parasite Plasmodium

falciparum life cycle

Xue Li1, Sudhir Kumar2, Marina McDew-White1,

Meseret Haile2, Ian Cheeseman1, Scott Emrich3, Katie

Button-Simons3, François Nosten4, Stefan Kappe2,

Michael Ferdig3, Tim Anderson1, Ashley Vaughan2 1Texas Biomedical Research Institute, San Antonio,

TX, United States, 2Seattle Children’s Research

Institute, Seattle, WA, United States, 3University of

Notre Dame, Notre Dame, IN, United States, 4Shoklo

Malaria Research Unit, Mae Sot, Thailand

12:35 p.m.

LB-5538

Plasmodium falciparum Pfs47 gene as a marker

for origin and risk of transmission of imported

malaria

Alvaro Molina-Cruz1, Ankit Dwivedi2, Jacob

Almagro-Garcia3, Giovanna Carpi4, Joana C. Silva2,

Carolina Barillas-Mury1 1Laboratory of Malaria and Vector Research, National

Institute of Allergy and Infectious Diseases, National

Institutes of Health, Rockville, MD, United

States, 2Institute for Genomic Sciences, University of

Maryland School of Medicine, Baltimore, MD, United

States, 3Wellcome Centre for Human Genetics,

Nuffield Department of Medicine, University of

Oxford, Oxford, United Kingdom, 4Department of

Biological Sciences, Purdue University, West

Lafayette, IN, United States

12:45 p.m.

LB-5539

A multi-faceted approach for genotyping and

assessing clonality of Plasmodium falciparum

malaria parasites

Mariko Kanai, Tomas Yeo, Satish K. Dhingra,

Josefine Striepen, Sachel Mok, David Fidock

Columbia University Irving Medical Center, New York,

NY, United States

Page 8: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

7

Late-Breaker Abstract Session 133

Late-Breakers in Malaria

Oral Presentations

National Harbor 3 (National Harbor Level)

Saturday, November 23, 12:15 p.m. - 1:30 p.m.

12:55 p.m.

LB-5540

The Malaria Cell Atlas: Understanding

transcriptional variation across the Plasmodium

life-cycle using single-cell RNA-seq

Virginia M. Howick1, Andrew Russell1, Tallulah

Andrews1, Kathrin Whitmer2, Eliana Real2, Farah

Dahalan2, Joshua Blight2, Silvain Pinaud1, Haynes

Heaton1, Adam Reid1, Hellen Butungi3, Tom Metcalf1,

Lisa Verzier4, Julian Rayner1, Jeremy Herren5,

Matthew Berriman1, Oliver Billker6, Jake Baum2,

Martin Hemberg1, Arthur Talman7, Mara Lawniczak1 1Wellcome Sanger Institute, Hinxton, United

Kingdom, 2Imperial College, London, United

Kingdom, 3University of the Witswatersrand,

Johannesburg, South Africa, 4Walter and Eliza Hall

Institute of Medical Research, Parkville,

Australia, 5International Centre of Insect Physiology

and Ecology, Nairobi, Kenya, 6Laboratory for

Molecular Infection Medicine Sweden, Umea,

Sweden, 7MIVEGEC, Montpellier, France

1:05 p.m.

LB-5541

A Plasmodium falciparum protein, RON3, is

required for the functional translocation of

exported proteins and glucose uptake

Leanne M. Low1, Yvonne Azasi1, Emma S.

Sherling2, Matthias Garten3, Joshua Zimmerberg3,

Takafumi Tsuboi4, Joseph Brzostowski1, Jianbing Mu1,

Michael J. Blackman2, Louis H. Miller1 1NIAID/NIH, Rockville, MD, United States, 2The

Francis Crick Institute, London, United

Kingdom, 3NICHD/NIH, Bethesda, MD, United

States, 4Ehime University, Matsuyama, Japan

1:15 p.m.

LB-5542

A Phase IIa, Open-label, CHMI Study to

Evaluate the Efficacy, Immunogenicity and

Safety of a Fractional (Fx) Booster dose of

RTS,S/AS01E Administered to Healthy Adults

Previously Receiving Various Primary Dose

Schedules of RTS,S/AS01E or RTS,S/AS01B in a

Sporozoite Challenge Model

James E. Moon, on behalf of the RTS,S Working

Group

Walter Reed Army Institute of Research, Silver

Spring, MD, United States

Page 9: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

Poster Session 26

Poster Session A

Late Breakers in Basic Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Thursday, November 21, Noon - 1:45 p.m.

Arthropods/Entomology ........................................................#LB-5000 through LB-5013

Bacteriology and Diarrhea .....................................................#LB-5014 through LB-5016

Helminths - Nematodes .........................................................#LB-5017 through LB-5023

HIV and Tropical Co-Infections ...............................................#LB-5024 through LB-5025

Malaria ...............................................................................#LB-5026 through LB-5055

Pneumonia, Respiratory Infections and Tuberculosis .................#LB-5056 through LB-5058

Viruses ...............................................................................#LB-5059 through LB-5068

Water, Sanitation, Hygiene and Environmental Health ..............#LB-5069

LB-5000

Vector competence and the susceptibility

of Anopheles mosquitoes to Vivax malaria-

infected blood from Thai patients and non-

human primate malaria P. cynomolgi infection

Suparat Chairuksa1, Amnart Kayha1, Ratawan

Ubalee1, Siriporn Phasomkusolsil1, Waranya Buadok1,

Supakit Wanasit1, Nattapat Rochanarutaiprida1,

Vichit Phunkitchar1, Heung Chul Kim2, Silas A

Davidson1, Terry A Klein2 1Department of Entomology, US Army Medical

Component, Armed Forces Research Institute of

Medical Sciences, 315/6 Rajvithi, Phayathai,

Bangkok, Thailand, 2Medical Department Activity-

Korea (MEDDAC-K)/65th Medical Brigade, Unit

15281, Box 754, Seoul, APO AP 96205, Korea,

Republic of

LB-5001

Structure of Culex quinquefasciatus D7L1

salivary protein bound to ADP

Andrew S. Paige

National Institutes of Health, Rockville, MD, United

States

LB-5002

Aedes aegypti salivary D7 proteins inhibit host

vasoconstriction and platelet aggregation at

the bite site

Ines Martin-Martin, Paola Valenzuela Leon, Steven

Brooks, Olivia Kern, Brian Bonilla, Hans Ackerman,

Eric Calvo

NIAID/NIH, Rockville, MD, United States

LB-5003

Exploring a novel Culex

quinquefasciatus protein family and its

implications for disease transmission

Olivia Kern

National Institutes of Health, Rockville, MD, United

States

LB-5004

Comparison of Mosquito Salivary Gland Extracts

And Saliva

Brian Bonilla

NIH/NIAID, Rockville, MD, United States

LB-5005

Have Cotton pest control strategies

(conventional, organic and transgenic) an

impact on insecticide resistance in Anopheles

gambiae s.l. populations in Burkina Faso, West

Africa?

Olivier GNANKINE1, Moussa NAMOUNTOUGOU2,

Diloma Dieudonné SOMA2, Thierry BALDET3,

Abdoulaye DIABATE4, Roch Kounbobr DABIRE4 1Université Joseph KI-ZERBO, Ouagadougou, Burkina

Faso, 2Université Nazi Boni, Bobo-Dioulasso, Burkina

Faso, 3CIRAD, Montpellier, France, 4IRSS/CNRST,

Bobo-Dioulasso, Burkina Faso

Page 10: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

9

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5006

Minimal genetic differentiation of the malaria

vector Nyssorhynchus darlingi associated with

forest cover level in Amazonian Brazil

Jan E. Conn1, Catharine Prussing1, Kevin J.

Emerson2, Sara A. Bickersmith1, Maria Anice Mureb

Sallum3 1Wadsworth Center, NYSDOH, Slingerlands, NY,

United States, 2St. Mary’s College of Maryland, St.

Mary’s City, MD, United States, 3Universidade de São

Paulo, São Paulo, Brazil

LB-5007

To spray or target malaria another way:

Entomological intelligence to guide the

implementation of Indoor Residual Spraying is

southern Mozambique

Celso Antonio Alafo

University of Witwatersrand, Johannesburg, South

Africa

LB-5008

Bacteriophage mediated modulation of

mosquito microbiota

Chinmay Tikhe, George Dimopoulos

Johns Hopkins Bloomberg School of Public Health,

Baltimore, MD, United States

LB-5009

Neuroendocrine interactions in Rhodnius

prolixus immune system: ecdysone importance

on gut microbiota and basal immunity

Cecilia S. Vieira, Caroline S. Moraes, Marcela B.

Figueiredo, Daniele P. Castro, Patricia Azambuja

Oswaldo Cruz Institute, Rio de Janeiro, Brazil

LB-5010

Deciphering regulation microRNAs in the

disease vector Aedes aegypti

Emre Aksoy

University of California, Riverside, Riverside, CA,

United States

LB-5011

Disrupting female flight in the vector Aedes

aegypti

Sarah O'Leary, Zach N. Adelman

Texas A&M University, College Station, TX, United

States

LB-5012

Something old, something new: Revisiting and

novel applications for wing scale counting as a

tool for age-grading An. gambiae

Lyndsey Gray1, Bryce Asay1, Emmanuel D.

Sougué2, Anyirekun F. Some2, Roch K. Dabiré2, Sunil

Parikh3, Brain D. Foy1 1Colorado Sate University, Fort Collins, CO, United

States, 2Institut de Recherche en Sciences de la

Santé, Bobo-Dioulasso, Burkina Faso, 3Yale

University, New Haven, CT, United States

LB-5013

Characterization of mosquito cell populations

through microRNA expression profiling

Kendra M. Quicke1, Aaron C. Brault2, Greg D. Ebel1 1Colorado State University, Fort Collins, CO, United

States, 2Centers for Disease Control and Prevention,

Fort Collins, CO, United States

LB-5014

A Rapid antigen and antibody ribosome display

for the selection of antibodies to multiple

antigens

Adinarayana Kunamneni1, Steven Bradfute2,

Angray S Kang3, Ravi Durvasula1 1Loyola University Chicago, Maywood, IL, United

States, 2University of New Mexico, Albuquerque, NM,

United States, 3Queen Mary University of London,

London, United Kingdom

Page 11: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

10

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5015

Heterogeneity in ETEC and Shigella infections:

a subnational approach quantifying risk,

mortality, morbidity, and stunting in children

under five years of age from 11 African

countries

Karoun H. Bagamian1, John D. Anderson1, Farzana

Muhib2, Oliver Cumming3, Lindsey A. Laytner1,

Thomas F. Wierzba4, Richard Rheingans5 1University of Florida, Gainesville, FL, United

States, 2PATH, Washington, DC, United

States, 3London School of Hygiene and Tropical

Medicine, London, United Kingdom, 4Wake Forest

School of Medicine, Winston Salem, NC, United

States, 5Appalachian State University, Boone, NC,

United States

LB-5016

Metagenomic analysis of altered gut microbiota

after the administration of bovine LF as

preventive treatment against diarrhea

Luis Gonzalez, Yesenia Filio, Pablo Tsukayama,

Theresa Ochoa

Universidad Peruana Cayetano Heredia, Lima, Peru

LB-5017

Isolation and Characterization of a

Bacteriophage of Wolbachia Endobacteria

from Allonemobius Crickets in Missouri

Jonah L. Kupritz, Gary J. Weil, Peter U. Fischer

Washington University School of Medicine, St. Louis,

MO, United States

LB-5018

Capillaria hepatica in humans and rodents from

Lofa County, Liberia

Kerstin Fischer1, Lincoln Gankpala2, Fatorma K.

Bolay2, Peter Uwe Fischer1 1Washington University School of Medicine, St. Louis,

MO, United States, 2Department of Public Health and

Medical Research, National Public Health Institute of

Liberia, Charlesville, Liberia

LB-5019

Modeling the metabolic interplay between a

parasitic worm and its bacterial endosymbiont

allows the identification of novel drug targets

David M. Curran1, Alexandra Grote2, Nirvana

Nursimulu1, Drew Jones2, Elodie Ghedin2, John

Parkinson1 1The Hospital for Sick Children, Toronto, ON,

Canada, 2New York University, New York, NY, United

States

LB-5020

The effects of transmission intensity and

parasite aggregation in the human host on the

likelihood of being able to interrupt the

transmission of soil transmitted helminths by

mass drug administration alone

Marleen Werkman1, Robert Hardwick1, Jaspreet

Toor2, James Truscott1, Roy M. Anderson1 1Imperial College London, London, United

Kingdom, 2University of Oxford, Oxford, United

Kingdom

LB-5021

Evaluating the feasibility of conducting

enhanced mass drug administration and the

Test- Treat-Track- Test strategy in

schistosomiasis endemic communities in

western Kenya

Rosemary Musuva1, Maurice R. Odiere1, Pauline N.

Mwinzi1, Edwin Nyagesoa1, Fredrick O. Rawago1,

Sultani H. Matendechero2, Carl H. Campbell3, Daniel

G. Colley3 1Kenya Medical Research Institute, Kisumu,

Kenya, 2Ministry of Health, Nairobi,

Kenya, 3University of Georgia, Athens, GA, United

States

LB-5022

Ascaris induced allergic airway disease is

mediated by STAT6-dependent and -

independent innate immune pathways

Jill E. Weatherhead1, John Morgan Knight1, Ana

Clara Gazzinelli-Guimaraes2, Ricardo Fujiwara2, Bin

Zhan1, Maria Elena Bottazzi1, Peter Hotez1, David

Corry1 1Baylor College of Medicine, Houston, TX, United

States, 2Universidade Federal de Minas Gerais, Belo

Horizonte, Brazil

Page 12: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

11

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5023

Angiostrongylus cantonensis infection

prevalence and intensity in its intermediate

gastropod hosts: the impact of host species,

host size and rainfall

Randi L. Rollins1, Robert H. Cowie2, Matthew C. I.

Medeiros2 1Department of Biology, University of Hawai‘i at

Mānoa, Honolulu, HI, United States, 2Pacific

Biosciences Research Center, University of Hawai‘i at

Mānoa, Honolulu, HI, United States

LB-5024

Prevalence of putative drug resistance

mutations in HIV-1 subtype C in Africa; an

individual sequence level meta-analysis

Nontokozo D. Matume1, Garvan Vines2, Elizabeth

Rogawski3, Pascal O. Bessong1 1University of Venda, Thohoyandou, South

Africa, 2University of Maryland, College Park, MD,

United States, 3University of Virginia, Charlottesville,

VA, United States

LB-5025

Co-infection with HIV may impact the

prevalence and severity of drug resistance in

the human malaria parasite Plasmodium

falciparum

Brandi Kenette Torrevillas1, Deborah Stiffler2,

Nathaniel Dizon2, V. Ann Stewart2, Shirley Luckhart1 1University of Idaho, Moscow, ID, United

States, 2Uniform Services University of the Health

Sciences, Bethesda, MD, United States

LB-5026

Increased duration following cotrimoxazole

prophylaxis discontinuation among PLHIV is

associated with asymptomatic malaria in a

malaria endemic setting in Uganda

Philip Orishaba, Pauline K. Byakika, Joan N.

Kalyango, Moses R. Kamya, Joaniter Nankabirwa

Makerere University, Kampala, Uganda

LB-5027

Plasmodium falciparum glutamic acid rich

protein-mediated adhesion of malaria-infected

RBCs to endothelium

Christopher Schwake, Athar Chishti

Tufts University, Boston, MA, United States

LB-5028

Evaluation of the residual effectiveness of

clothianidin for the control of pyrethroid

resistant malaria vectors in Lake Zone regions,

Tanzania

Jackline L. Martin1, Charles Kakila1, Karen Nelwin1,

Safari M. Kinung’hi1, Eric Lyimo1, Lucy David2, Doris

Mangalu1, Mubita Lifwatila3, Dismas Mwalimu4,

Naomi Serbantez5, George Greer6, Kristen George7,

Alphaxard Manjurano1, Ssanyu Nyinondi8 1NIMR Mwanza, Mwanza, Tanzania, United Republic

of, 2National Institute for Medical Research, Mwanza,

Tanzania, United Republic of, 3US President’s Malaria

Initiative, Vectorlink Project, Mwanza, Tanzania,

Mwanza, Tanzania, United Republic of, 4National

Malaria Control Program, Ministry of Health,

Community Development, Gender, Elderly and

Children, Dodoma, Tanzania, Mwanza, Tanzania,

United Republic of, 5US President’s Malaria Initiative,

USAID, Dar es Salaam, Tanzania, Mwanza, Tanzania,

United Republic of, 6US President’s Malaria Initiative,

USAID, Dar es Salaam, Tanzania, Dar es Salaam,

Tanzania, United Republic of, 7US President’s Malaria

Initiative, USAID, Washington DC, USA, Washington,

United Kingdom, 8US President’s Malaria Initiative,

USAID Okoa Maisha Dhibiti Malaria Project,

Tanzania, Dar es Salaam, Tanzania, United Republic

of

LB-5029

Autoreactive Antibodies Correlate with

Protection from Febrile Malaria in Mali

Kelly A. Hagadorn1, Christine S. Hopp1, Jeff

Skinner1, Hemanta Kole1, Bethany Scott1, Mei Yan2,

Chengsong Zhu2, Quan-Zhen Li2, Safiatou Doumbo3,

Kassoum Kayentao3, Aissata Ongoiba3, Boubacar

Traore3, Silvia Bolland1, Peter D. Crompton1 1NIH, Rockville, MD, United States, 2University of

Texas Southwestern Medical Center, Dallas, TX,

United States, 3Malaria Research and Training

Center, University of Sciences, Techniques &

Technologies of Bamako, Bamako, Mali

LB-5030

FNDR-20123: A histone deacetylase (HDAC)

inhibitor as a novel antimalarial drug candidate

Shridhar Narayanan1, Vijay Kumar Potluri1, Brice

Campo2, Sergio Wittlin3, Radha Krishan Shandil1 1Foundation for Neglected Disease Research,

Bangalore, India, 2Medicines for Malaria Venture,

Geneva, Switzerland, 3Swiss TPH, Basel, Switzerland

Page 13: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

12

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5031

A single infection with a malaria parasite

protects mice from lethal autoimmune

glomerulonephritis

Laura Amo, Hemanta Kole, Bethany Scott, Chen-

Feng Qi, Juan Wu, Silvia Bolland

NIH, Rockville, MD, United States

LB-5032

Mapping drug-susceptible, multi-stage targets

and chemical genomic profiles using the NCATS

Malaria Active Collection

Richard T. Eastman1, Juliana Calit2, Bingbing

Deng1, Alison Roth3, Kazutoyo Miura1, Roberto R.

Moraes Barros4, Jianbing Mu1, Roxana Stefanescu5,

Andrew T. Girvin5, Jameson Travers1, Shayne

Frebert1, Misha Itkin1, Zina Itkin1, Hui Guo1, Danielle

Bougie1, Carleen Klumpp-Thomas1, Juliana M. Sa1,

Brandon Pybus3, Daniel Y. Bargieri2, Carole A. Long1,

Thomas E. Wellems1, Anton Simeonov1 1National Institutes of Health, Rockville, MD, United

States, 2University of São Paulo, São Paulo,

Brazil, 3Walter Reed Army Institute of Research,

Silver Spring, MD, United States, 4Federal University

of São Paulo, São Paulo, Brazil, 5Palantir

Technologies, Washington, DC, United States

LB-5033

An intravenous preparation of the antimalarial

OZ439 for nonhuman primate laboratory

studies

Juliana M. Sa1, Rebecca E. Salzman1, Viviana A.

Melendez-Muniz1, Christine E. Figan1, Roberto R.

Moraes-Barros1, Jeremy Burrows2, Larry Walker3,

Thomas E. Wellems1 1National Institutes of Health, Rockville, MD, United

States, 2Medicines for Malaria Venture, Geneva,

Switzerland, 33Campbell University, College of

Pharmacy & Health Sciences, Buies Creek, NC,

United States

LB-5034

Blocking Plasmodium host cell invasion using

small molecule inhibitors targeting an essential

protein-protein interaction

Geervani Daggupati1, Adam Yasgar2, Elena

Fernandez Alvaro3, Francisco Javier Gamo3, Anton

Simeonov2, Louis H. Miller4, Prakash Srinivasan1 11Malaria Research Institute, Dept. Molecular

Microbiology and Immunology, Johns Hopkins School

of Public Health, Baltimore, MD, United

States, 2National Center for Advancing Translational

Sciences, National Institutes of Health, Bethesda,

MD, United States, 3Tres Cantos Medicine

Development Campus, GlaxoSmithKline, Parque

Tecnológico de Madrid, Tres Cantos,

Spain, 4Laboratory of Malaria and Vector Research,

Division of Intramural Research, National Institute of

Allergy and Infectious Diseases, National Institutes

of Health, Bethesda, MD, United States

LB-5035

FLIM and Imaging Analysis of Plasmodium

falciparum Exposed to Artemisinin

Sean Connelly1, Zoë Levine1, Javier Manzella-

Lapeira2, Joseph Brzostowski2, Ludmila Krymskaya2,

Rifat Rahman1, Juliana Sá1, Thomas Wellems1 1Laboratory of Malaria and Vector Research, National

Institute of Allergy and Infectious Disease, National

Institutes of Health, Rockville, MD, United

States, 2Laboratory of Immunogenetics, National

Institute of Allergy and Infectious Disease, National

Institutes of Health, Rockville, MD, United States

LB-5036

Development of an ookinete and zygote

inhibition assay for prescreening of

transmission-blocking candidates

Ragavan Varadharajan Suresh1, Kazutoyo Miura1,

Bingbing Deng1, Luwen Zhou1, Mayumi Tachibana2 1National Institute of Allergy and Infectious Diseases,

National Institutes of Health, Rockville, MD, United

States, 2Division of Molecular Parasitology, Proteo-

Science Center, Ehime University, Toon, Ehime,

Japan

LB-5037

A common polymorphism in the druggable ion

channel PIEZO1 is associated with protection

from severe malaria

Christian N. Nguetse1, Natasha Purington2, Bikash

Shakya1, Emily R. Ebel3, Peter G. Kremsner4,

Thirumalaisamy P. Velavan5, Elizabeth S. Egan1 1Department of Pediatrics and Microbiology &

Immunology, Stanford University School of Medicine,

Stanford, CA, United States, 2Quantitative Sciences

Unit, Stanford University School of Medicine,

Stanford, CA, United States, 3Department of Biology,

Stanford University, Stanford, CA, United

States, 4Institute of Tropical Medicine, University of

Tübingen ; Centre de Recherches Médicales de

Lambaréné, Albert Schweitzer Hospital, Tübingen,

Germany, 5Institute of Tropical Medicine, University

of Tübingen ; Vietnamese-German Center for Medical

Research, Tübingen, Germany

Page 14: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

13

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5038

In vitro eryptosis assays: an evaluation of

apoptotic activities by antimalarial compounds

Xiannu Jin, Cameron Blount, Corttney Marquez,

Dominique Richardson, Justin Parks, Visal Min,

Shaylyn Scott, Alexandra Urman, William

McCalmont, Jason Sousa, Tanisha Robinson, Elke

Bergmann-Leitner, Gregory Reichard, Brandon Pybus

Walter Reed Army Institute of Research, Silver

Spring, MD, United States

LB-5039

Adjuvant selection and antigen dose affect

efficacy of RH5.1, Ripr and CyRPA antibodies in

an animal immunization model

Julie Healer1, Jennifer K. Thompson1, Cecille D.

Brown2, Jayne M. Christen2, Rajkannan

Rajagopalan3, Leanne Lucas3, Marianne M. Stanford3,

Lorraine Soisson4, Carter Diggs4, Robin Miller4, Amy

R. Noe2, Simon J. Draper5, Alan F. Cowman1 1Walter & Eliza Hall Institute of Medical Research,

Parkville, Australia, 2Leidos Life Sciences, Frederick,

MD, United States, 3IMV-Inc., Dartmouth, NS,

Canada, 4MVDP USAID, Washington DC, United

States, 5University of Oxford, Oxford, United

Kingdom

LB-5040

Population genetic analysis of Plasmodium

falciparum Circumsporozoite Protein in two

distinct ecological regions in Ghana

Elikplim A. Amegashie1, Alfred Amambua-Ngwa2,

Lucas Amenga-Etego3, Peter Ogoti1, Kevin Mbogoo1,

Anita Ghansah4 1Jomo Kenyatta University of Agriculture and

Technology, Nairobi, Kenya, 2Medical Research

Council Unit The Gambia at LSHTM, Banjul,

Gambia, 3West African Centre for Cell Biology and

Infectious Diseases,University of Ghana, Legon,

Accra, Ghana, 4Noguchi Memorial Institute of Medical

Research, College of Health Sciences, University of

Ghana, Accra, Ghana

LB-5041

Malaria during the first two years of life: a

population-based birth cohort study in

northwestern Brazil

Anaclara Pincelli1, Rodrigo Malavazi Corder1,

Rodrigo Medeiros de Souza2, Simone Ladeia-

Andrade3, Marly Augusto Cardoso1, Marcia Caldas

Castro4, Marcelo Urbano Ferreira1, for the MINA-

Brazil Working Group5 1University of Sao Paulo, Sao Paulo, Brazil, 2Federal

University of Acre, Cruzeiro do Sul, Brazil, 3Oswaldo

Cruz Institute - FIOCRUZ, Rio de Janeiro,

Brazil, 4Harvard T.H. Chan School of Public Health,

Boston, MA, United States

LB-5042

Investigation of antibody-mediated immune

mechanisms in pregnancy-associated malaria

Madeleine C. Wiebe1, Michael Hawkes1, Eliana

Arango2, Amanda Maestre2, Sedami Gnidehou3,

Stephanie K. Yanow1 1University of Alberta, Edmonton, AB,

Canada, 2Universidad de Antioquia, Medellin,

Colombia, 3University of Alberta Campus Saint-Jean,

Edmonton, AB, Canada

LB-5043

Vaccination with P. vivax MSP19-based

formulations protects mice from challenge with

hybrid P. berghei expressing PvMSP119

Irina Dobrescu, Tarsila Mendes de Camargo, Oscar

Murillo, Kelly Amorim, Claudio Romero Farias

Marinho, Silvia B. Boscardin, Irene Silva

Soares, Daniel Y. Bargieri

University of Sao Paulo, Sao Paulo, Brazil

LB-5044

Layer-by-Layer Multiple Antigen Nano-delivery

Platform for Malaria Vaccine

Yang Xu1, Brad Brooks1, Ziyou Zhou1, Moriya Tsuji2,

XiangPeng Kong3, Chris Tison1 1Luna Innovations Inc, Danville, VA, United

States, 2Aaron Diamond AIDS Research Center,

Affiliate of Rockefeller University, New York, NY,

United States, 3Department of Biochemistry and

Molecular Pharmacology, New York University School

of Medicine, New York, NY, United States

Page 15: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

14

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5045

Recombinant full-length extracellular VAR2CSA

protein variants differ in their antigenicity to

human antibody

Justin Y. Doritchamou1, Jonathan P. Renn2, Michal

Fried2, Lars Hviid3, Patrick E. Duffy2 1Laboratory of Malaria Immunology & Vaccinology,

National Institute of Allergy and Infectious Disease,

Rockville, MD, United States, 2Laboratory of Malaria

Immunology & Vaccinology, National Institute of

Allergy and Infectious Disease, Bethesda, MD, United

States, 3Center for Medical Parasitology, Faculty of

Health and Medical Sciences, University of

Copenhagen, Copenhagen – Denmark, Rockville, MD,

United States

LB-5046

Impact of Malaria in Pregnancy on Infant

Neurobehavioral Outcomes

Harriet L. S. Lawford1, Mercy A. Nuamah2, Felix

Botchway3, Samuel A. Oppong2, Ali Samba2,

Ebenezer V. Badoe4, Sailesh Kumar1, Anne CC Lee5,

Helen G. Liley1, Richard K. Gyasi6, Andrew A. Adjei6,

Samudragupta Bora1 1Mothers, Babies and Women's Health Program,

Mater Research Institute, Faculty of Medicine, The

University of Queensland, South Brisbane,

Australia, 2Department of Obstetrics and Gynecology,

University of Ghana Medical School, Korle Bu, Accra,

Ghana, 3Central Diagnostic Laboratory, Korle Bu

Teaching Hospital, Accra, Ghana, 4Department of

Child Health, University of Ghana Medical School,

Korle Bu, Accra, Ghana, 5Department of Pediatric

Newborn Medicine, Brigham and Women’s Hospital,

Harvard Medical School, Boston, MA, United

States, 6Department of Pathology, University of

Ghana Medical School, Korle Bu, Accra, Ghana

LB-5047

The tug of war of resistance competition

dynamics

Tamsin E. Lee, Melissa A. Penny

Swiss Tropical and Public Health Institute, Basel,

Switzerland

LB-5048

Effective integrated community case

management using simple eMobile system for

real-time data collection in six provinces of

Angola

Alfredo Pascoal Francisco

World Vision International, Angola, Luanda, Angola

LB-5049

The Impact of Indoor Residual Spraying on

Malaria Transmission in Obuasi Municipality of

Ghana

Kwame Desewu, Ignatius Williams, Samuel Asiedu,

Sylvester Segbaya, Rosemary Ampofo-Bekoe,

Nicholas Ato Egyir, Bernard Afoakwah, Gilbert

Dossah, Paul Osei-Bonsu, Grace Oppong, Francis

Amankwah, Joseph Mwinikubu Vulgate

Anglogold Ashanti Malaria Control Limited, Obuasi,

Ghana

LB-5050

Genomics of P. vivax on the China-Myanmar

Border

Awtum M. Brashear1, Liwang Cui2, Qi Fan3 1Penn State, University Park, PA, United

States, 2University South Florida, Tampa, FL, United

States, 3Dalian Insttitute of Bioechnology, Dalian,

China

LB-5051

Proteome-wide screening identifies highly

effective targets of cross-species protective

immunity against malaria

Mengistu Seid, David J. Pattinson, Carla Proietti,

Daniel Browne, Claire Loiseau, Jamie L.

Brady, Denise L. Doolan

James Cook University, Cairns, Australia

LB-5052

Using travel history data from Zimbabwe’s

case-based malaria surveillance system to

understand the risk of importation in malaria

elimination districts in 2018

Busisani Dube1, Brighton Gambinga2, Dr. Patience

Dhliwayo1, Munashe Madinga2, Dr. Abaden Svisva2,

Deepa Pindolia2, Dr. Joseph Mberikunashe1 1Zimbabwe National Malaria Control Programme,

Harare, Zimbabwe, 2Clinton Health Access Initiative,

Harare, Zimbabwe

Page 16: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

15

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5053

High patient adherence and prescriber

compliance to artemether-lumefantrine therapy

for uncomplicated

Plasmodium falciparum malaria in Sierra Leone,

2018

Samuel J. Smith1, Anitta R. Kamara1, Thomas K.

Ansumana1, Musa Sillah-Kanu1, Foday Sahr2, Marian

Warsame3, Max Petzold3 1National Malaria Control Program, Ministry of Health

and Sanitation, Freetown, Sierra Leone, 2University

of Sierra Leone, Freetown, Sierra

Leone, 3Gothenburg University, Gothenburg, Sweden

LB-5054

Assessment of artesunate injectables

consumption in selected public hospitals of the

Tigray region of northern Ethiopia: Evidence-

based guidance to improve medicine use

Belete Ayalneh1, Maressa Weldegabriel1, Regasa

Bayisa2, Fikreslassie Alemu1, Getachew Ayalew1,

Workineh Getahun1, Daniel Tadesse1, Tesfaye Seifu1,

Edmealem Ejigu1 1Chemonics, Addis Ababa, Ethiopia, 2Ministry of

Health, Addis Ababa, Ethiopia

LB-5055

Characterization of multiple full-length

VAR2CSA recombinant proteins expressed in a

mammalian system for placental malaria

vaccine development

Jonathan P. Renn, Justin Doritchamou, Robert

Morrison, Michal Fried, Patrick E. Duffy

National Institutes of Health, BETHESDA, MD, United

States

LB-5056

Analytical performance of new Lateral Flow

Immunoassay for the detection of Tuberculosis

in human urine

Brianda Barrios-Lopez1, Lex Ball1, Benjamin

Grant1, Lech Ignatowicz2, Beston Hamasur2, Akos

Somoskovi3, John T. Connelly1 1Intellectual Ventures Laboratory, Bellevue, WA,

United States, 2Biopromic AB, Stocholm,

Sweden, 3Global Good Fund, Bellevue, WA, United

States

LB-5057

Reconstruction of

fragmented Mycobacterium tuberculosis DNA

from urine for PCR detection

Mindy Leelawong, Frederick Haselton

Vanderbilt University, Nashville, TN, United States

LB-5058

Clinical characteristics and molecular detection

of Bordetella pertussis in hospitalized children

with a clinical diagnosis of whooping cough in

Peru

Wilmer Silva-Caso1, Cristina del Valle Vargas2,

Ronald Aquino-Ortega1, Luis J. del Valle3, Erico

Cieza-Mora4, Jorge Bazan-Mayra5, Victor Zavaleta-

Gavidia6, Miguel Angel Aguilar-Luis1, Hernan

Cornejo-Pacherres5, Johanna Martin-Luna1, Angela

Cornejo-Tapia1, Juana del Valle-Mendoza1 1Universidad Peruana de Ciencias Aplicadas, Lima,

Peru, 2Facultad de Medicina. Univesidad de

Barcelona., Barcelona, Spain, 3Barcelona Research

Center for Multiscale Science and Engineering,

Departament d’Enginyeria Quıímica, EEBE,

Universidad Politècnica de Catalunya, Barcelona,

Spain, 4Hospital Regional Docente de Cajamarca.

Cajamarca, Cajamarca, Peru, 5Laboratorio Regional

de Cajamarca, Dirección Regional de Salud de

Cajamarca (DIRESA). Cajamarca, Cajamarca,

Peru, 6Laboratorio Regional de Cajamarca, Dirección

Regional de Salud de Cajamarca (DIRESA).

Cajamarcaas Aplicadas, Cajamarca, Peru

LB-5059

Previous Exposure to Venezuelan Equine

Encephalitis Protects Against Chikungunya

Infection in Embryoid Bodies

Emily M. Schultz, Ty J. Jones, Hannah L. Clamp,

Kelli L. Barr

Baylor University, Waco, TX, United States

LB-5060

Effects of Chikungunya Infection on Astrocytes

and Mixed Glutamic and GABAergic Neurons

Emma G. Fraley, Emily M. Schultz, Hannah L.

Clamp, Kelli L. Barr

Baylor University, Waco, TX, United States

Page 17: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

16

Poster Session A

Late Breakers in Basic Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5061

Modulation of host inflammatory response to

mosquito salivary protein during Arbovirus

infection

GAURAV SHRIVASTAVA

National Institutes of Health, Rockville, MD, United

States

LB-5062

Role of mosquito salivary proteins in Zika virus

transmission

Paola Valenzuela

NIH, ROCKVILLE, MD, United States

LB-5063

A Novel Stem Cell-Derived Hepatic Cell Line for

Studying Dengue Pathogenesis and Therapy

Kessiri Kongmanas1, Nuntaya Punyadee1, Kasima

Wasuworawong1, Adisak Sonjaeng1, Yongyut

Pewkliang2, Siriphan Manocheewa3, Somchai

Thiemmeca1, Khanit Sa-ngiamsuntorn4, Kym Francis

Faull5, Suradej Hongeng6, Panisadee Avirutnan1 1Division of Dengue Hemorrhagic Fever Research,

Faculty of Medicine Siriraj Hospital, Mahidol

University, Bangkok, Thailand, 2Excellent center for

drug discovery, Faculty of Science, Mahidol

University, Bangkok, Thailand, 3Siriraj Metabolomics

and Phenomics Center, Faculty of Medicine Siriraj

Hospital, Mahidol University, Bangkok,

Thailand, 4Department of Biochemistry, Faculty of

Pharmacy, Mahidol University, Bangkok,

Thailand, 5Pasarow Mass Spectrometry Laboratory,

Jane and Terry Semel Institute for Neuroscience and

Human Behavior, David Geffen School of Medicine,

University of California Los Angeles, Los Angeles, CA,

United States, 6Department of Pediatrics, Faculty of

Medicine Ramathibodi Hospital, Mahidol University,

Bangkok, Thailand

LB-5064

Tryptase promotes endothelial permeability

and shock during dengue infection and is

correlated with disease severity

Abhay P. S. Rathore1, Chinmay Mantri2, Siti A.

Aman2, Ayesa Syenina2, Justin Ooi2, Cyril J. Jagaraj2,

Chi Ching Goh3, Hasitha Tissera4, Annelies Wilder-

Smith5, Lai Guan Ng3, Duane J. Gubler2, Ashley L. St.

John2 1Duke University, Durham, NC, United States, 2Duke-

NUS Medical School, Singapore,

Singapore, 3Singapore Immunology Network,

Singapore, Singapore, 4Sri Lanka Ministry of Health,

Colombo, Sri Lanka, 5Nanyang Technological

University, Singapore, Singapore

LB-5065

Pseudotype-lentiviral production to study the

effect of novel genetic signatures of

chikungunya virus E1 glycoprotein found in

Puerto Rico

Jetsimary Garcia-Justiniano, Yashira Garcia-

Flores, Pablo Lopez, Vanessa Rivera-Amill

Ponce Health Sciences University, Ponce, PR, United

States

LB-5066

Susceptibility of human megakaryocytes to

Severe Fever with Thrombocytopenia

Syndromevirus (SFTSV) infection

Diana Fernandez, Nathen E. Bopp, Patricia V.

Aguilar

Institute for Human Infections and Immunity, Center

for Tropical Diseases, and Department of Pathology,

University of Texas Medical Branch, Galveston, TX,

United States

LB-5067

Transcriptome analysis of Aedes

aegypti mosquito ovaries following Zika virus

infection

Dilip K. Nag

Wadsworth Center, Slingerlands, NY, United States

LB-5068

The evolutionary fitness of Zika virus during

spread from Africa to Asia to the Americas

Jianying Liu, Yang Liu, Chao Shan, Sherry Haller,

Ruimei Yun, Pei-Yong Shi, Scott Weaver

UTMB, Galveston, TX, United States

LB-5069

Clean Water 4 Life: An Innovative Technical

Approach to Solving Global Water Challenges

Samantha Dittrich1, Lauren Richardson1, Dave

Luke2, Jared Matthews2, Chris Ernst2 1Merrick & Company, Arlington, VA, United

States, 2Merrick & Company, Denver, CO, United

States

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17

Poster Session 26

Poster Session A

Late Breakers in Clinical and Applied Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Thursday, November 21, Noon - 1:45 p.m.

Global Health .......................................................................#LB-5070 through LB-5092

Helminths - Nematodes .........................................................#LB-5093 through LB-5100

Integrated Control Measures for Neglected Tropical Diseases .....#LB-5101 through LB-5109

Malaria ...............................................................................#LB-5110 through LB-5147

One Health: Interface of Human Health/Animal Diseases ..........#LB-5148 through LB-5156

Viruses ...............................................................................#LB-5157 through LB-5169

LB-5070

Performance of the G6PD biosensor as a point

of care diagnostic in newborn

Sirinart Chomean, Pairat Pengboon, Chollanot

Kaset

Faculty of Allied Health Sciences, Thammasat

University, Pathum Thani, Thailand

LB-5071

Interpreter Provider Collaboration:

Investigating the barriers preventing effective

communication with patients of Limited English

Proficiency

Hannah Lee, Michael Shyne, Hope Pogemiller

University of Minnesota, Minneapolis, MN, United

States

LB-5072

Using open-source 3D printable GPS trackers to

characterize the role of human population

movement on malaria epidemiology in the

Peruvian Amazon river networks

Gabriel Carrasco-Escobar1, Kimberly Fornace2,

Daniel Wong1, Pierre G. Padilla-Huamantinco1, Jose

A. Saldaña-Lopez1, Ober E. Castillo-Meza1, Armando

E. Caballero-Andrade1, Edgar Manrique1, Jorge Ruiz-

Cabrejos1, Jose L. Barboza1, Hugo Rodriguez3,

German Henostroza4, Marcia C. Castro5, Dionicia

Gamboa1, Alejandro Llanos-Cuentas1 1Universidad Peruana Cayetano Heredia, Lima,

Peru, 2London School of Hygiene and Tropical

Medicine, London, United Kingdom, 3Dirección

Regional de Salud Loreto, Loreto, Peru, 4University of

Alabama at Birmingham, Birmingham, AL, United

States, 5Harvard T.H. Chan School of Public Health,

Boston, MA, United States

LB-5073

Safety of oral ivermectin during pregnancy: a

systematic review and meta-analysis

Patricia Nicolas1, Marta F. Maia2, Quique Bassat1,

Kevin C. Kobylinski3, Wuelton Monteiro4, N. Regina

Rabinovich1, Clara Menéndez1, Azucena Bardají1,

Carlos Chaccour1 1ISGlobal, Barcelona, Spain, 2KEMRI Wellcome Trust

Research Programme, Kilifi, Kenya, 3Armed Forces

Research Institute of Medical Sciences, Bangkok,

Thailand, 4Fundação de Medicina Tropical Dr. Heitor

Vieira Dourado, Manaus, Brazil

LB-5074

Utility of chromogenic bacteriological media for

the rapid detection, differentiation and

susceptibility testing from positive blood

culture bottles

Lourens Robberts1, Josh Chenoweth2, Alex Owusu-

Ofori3, George Oduro4, Benjamin Espinosa5, Danielle

Clark2 1American Society for Microbiology, Washington DC,

United States, 2The Henry M. Jackson Foundation,

Bethesda, MD, United States, 3, Kwame Nkrumah

University of Science and Technology, Kumasi,

Ghana, 4Komfo Anokye Teaching Hospital, Kumasi,

Ghana, 5Naval Medical Research Center, Frederick,

MD, United States

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18

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5075

A Novel Approach to Introducing Diagnostic

Bacteriology in a Resource-limited Setting

Saturday Quellie1, Gaeduo Stewart2, William

Walker1, Lamin Meyers1, Lourens Robberts3, Mara

Jana Broadhurst3, Michelle Rozo4, Jefferson Sibley1,

Fatorma Bolay5, Josh G. Chenoweth4, Benjamin

Espinosa6, Danielle V. Clark4 1Phebe Hospital, Gbarnga, Liberia, 2AfricaBio

Enterprises Inc., Monrovia, Liberia, 3American

Society for Microbiology, Washington DC, United

States, 4The Henry M. Jackson Foundation, Bethesda,

MD, United States, 5National Public Health Institute

of Liberia, Monrovia, Liberia, 6Naval Medical Research

Center, Frederick, MD, United States

LB-5076

Collaboration between the Austere

environments Consortium for Enhanced Sepsis

Outcomes (ACESO) and Phebe Hospital is a

model for clinical research in Liberia

Jefferson Sibley1, Saturday Quellie1, Gaeduo K.

Stewart2, Clarine S. Vaughn2, Candace B. Eastman2,

Melissa Bradshaw3, Josh G. Chenoweth3, Benjamin

Espinosa4, Charmagne Beckett5, Anne Fox6, Andrew

Letizia6, Danielle V. Clark3, Fatorma K. Bolay7,

Mosoka P. Fallah7 1Phebe Hospital, Gbarnga, Liberia, 2AfricaBio

Enterprises Inc., Monrovia, Liberia, 3The Henry M.

Jackson Foundation, Bethesda, MD, United

States, 4Naval Medical Research Center, Frederick,

MD, United States, 5Naval Medical Research Center,

Silver Spring, MD, United States, 6Naval Medical

Research Unit 3 Ghana Detachment, Accra,

Ghana, 7National Public Health Institute of Liberia,

Monrovia, Liberia

LB-5077

Bacteriological profile, antibiotic prescription,

and antimicrobial resistance patterns in

patients with suspected sepsis admitted at

Komfo Anokye Teaching Hospital (KATH)

Emergency Department

Eno Biney1, George Oduro1, Chris Oppong1, Bernard

Arhin1, Isaac Boakye1, Yaw Boaitey1, Alex Owusu-

Ofori2, Daniel Ansong2, Anne Fox3, Andrew Letizia3,

Josh G. Chenoweth4, Charmagne Beckett5, Benjamin

Espinosa6, Danielle V. Clark4 1Komfo Anokye Teaching Hospital, Kumasi,

Ghana, 2Kwame Nkrumah University of Science and

Technology, Kumasi, Ghana, 3Naval Medical

Research Unit 3 Ghana Detachment, Accra,

Ghana, 4The Henry M. Jackson Foundation,

Bethesda, MD, United States, 5Naval Medical

Research Center, Silver Spring, MD, United

States, 6Naval Medical Research Center, Frederick,

MD, United States

LB-5078

Contribution of Rapid Diagnostic Test Use as a

Platform for Developing Epidemiologic Capacity

in the Case Management of Patients with

Suspected Sepsis at Komfo Anokye Teaching

Hospital

George Oduro1, Kwaku Nyame1, Bernard Arhin1,

Isaac Boakye1, Chris Oppong1, David Sambian1, Alex

Owusu-Ofori1, Daniel Ansong2, Anne Fox3, Andrew

Letizia3, Josh G. Chenoweth4, Charmagne Beckett5,

Benjamin Espinosa6, Danielle V. Clark4 1Komfo Anokye Teaching Hospital, Kumasi,

Ghana, 2Kwame Nkrumah University of Science and

Technology, Kumasi, Ghana, 3Naval Medical

Research Unit 3 Ghana Detachment, Accra,

Ghana, 4The Henry M. Jackson Foundation,

Bethesda, MD, United States, 5Naval Medical

Research Center, Silver Spring, MD, United

States, 6Naval Medical Research Center, Frederick,

MD, United States

LB-5079

The impact of extreme rainfall events on the

incidence of mosquito-borne diseases: a

systematic literature review

Jenna Coalson, Elizabeth J. Anderson, Valerie

Madera Garcia, Ellen Santos, Danielle Richard, Joy

Luzingu, James Romine, Ashley Little, Amanda

Okello, Bryan Dominguez, Mona Arora, Joshua

Arnbrister, Kacey Ernst

University of Arizona, Tucson, AZ, United States

LB-5080

Is this rash measles?

Sandy Hoar

George Washington University, Wasington, DC,

United States

LB-5081

Understanding the breadth and specificity of

the neutralizing antibody response to Takeda’s

tetravalent dengue vaccine

Christina DeMaso, Lovkesh Karwal, David

Dominguez, Zhang-Li Springer, Melissa Zahralban-

Steele, Sunil Palani, Subash Das, Hansi Dean,

DEN203 and DEN205 study groups

Vaccine Business Unit, Takeda Pharmaceuticals,

Cambridge, MA, United States

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19

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5082

The effects of Zinc supplementation in children

with sickle cell disease in Western Kenya: a

pilot study

Lucas O. Tina1, Sports Ishmael2, David Ogolla3,

Winnie Chepkemoi3, Amos Ndhere4, Irene Omollo3,

Janet Oyieko2, Allan Otieno2, Bernhards Ogutu1 1KEMRI-Centre for Clinical Research/Centre for

Research in Therapeutic Sciences (CREATES),

Strathmore University, Nairobi, Kenya, 2KEMRI-

Centre for Clinical Research, Kisumu, Kenya, 3Centre

for Research in Therapeutic Sciences (CREATES),

Strathmore University, Nairobi, Kenya, 4Africa

Clinical Research Management, Kisumu, Kenya

LB-5083

Perceptions and Feasibility of Digital

Interventions Among Tuberculosis patients in

Cambodia: A Qualitative Study of Video

Observed Therapy

Lila Rabinovich1, Joanne Yoong1, James Molton2,

Ooi Wei Tsang3 1University of Southern California, Washington DC,

United States, 2National University Hospital,

Singapore, Singapore, 3National University of

Singapore, Singapore, Singapore

LB-5084

The impact on mortality of treating low-

glycemia in critically ill children on arrival to

hospital admitted to in Malawi -The SugarFACT

trial

Fatsani Ngwalangwa1, Naomi Muheka1, Henderson

Masanjala2, Queen Dube2, Josephine Langton1, Tim

Baker3, Helena Hildenwall3 1University of Malawi, College of Medicine, Blantyre,

Malawi, 2Queen Elizabeth Central Hospital, Blantyre,

Malawi, 3Karolinska insitutet-Global Health- Health

Systems and Policy Research Groups, Stockholm,

Sweden

LB-5085

Acceptability and feasibility of an amino acid-

based oral rehydration solution for

environmental enteric dysfunction in Kenyan

children

Jaclyn Delarosa1, Michael B. Arndt1, Alfred Odhiambo

Ochola2, Peninah Murunga2, James K. Mukabi2,

Robert K. Choy1, Rahsan Erdem1, Eugenio L. de

Hostos1, Gwen Ambler1

1PATH, Seattle, WA, United States, 2PATH, Nairobi,

Kenya

LB-5086

Socio-Demographic Pattern And Correlates of

10-Year Absolute Cardiovascular Risks Among

Public Servants in Ondo State, Nigeria: A Cross

Sectional Study

ISAAC OLUGBENGA ALADENIYI, Adewale

Akinbolasere, Adenike C. Enikuomehin

Ministry of Health, Akure, Nigeria

LB-5087

Seroprevalence of dengue among children in

Cebu, Philippines using indirect ELISA as

compared to neutralization tests just prior to

mass vaccination

Anna Lena Lopez1, Cameron Adams2, Michelle

Ylade1, Ramesh Jadi2, Jedas Veronica Daag1, Kristal

An Agrupis1, Leidenia Castro1, Deok Ryun Kim3, In-

kyu Yoon3, Maria Wilda Silva4, Jacqueline Deen1,

Aravinda de Silva5 1University of the Philippines Manila, Manila,

Philippines, 2University of North Carolina, Chapel Hill,

NC, United States, 3International Vaccine Institute,

Seoul, Korea, Republic of, 4Department of Health,

Manila, Philippines, 5University of North Carolina,

Chapel Hill, NC, United States

LB-5088

Building Disease Surveillance Capacity in the

Peruvian Navy with Mobile Data Collection and

Enhanced Analytics

Shraddha Patel

Johns Hopkins Applied Physics Laboratory, Laurel,

MD, United States

LB-5089

Comparison of Active and Passive Surveillance

of Dengue in Machala, Ecuador

Christina D. Lupone1, Melissa Vitale1, Aileen

Kenneson-Adams1, Robinson Jaramillo Ochoa2, Tania

Ordoñez2, Efráin Beltran-Ayala2, Timothy P. Endy1,

Paula Rosenbaum1, Anna Stewart-Ibarra1 1SUNY Upstate Medical University, Syracuse, NY,

United States, 2Ministry of Health, Machala, Ecuador

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20

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5090

In Vitro Diagnostics Regulation, Quality, and

Health Delivery in Low Middle-Income

Countries - Recent Trends from the Field

FAROUK A. UMARU1, Daniel Bembpong1, Elliot

Cowan2, Godfred Kweku Fedihan3 1United States Pharmacopeal Convention, Inc.,

Rockville, MD, United States, 2Partners In

Diagnostics, Rockville, MD, United States, 3United

States Pharmacopeal Convention, Inc., Accra, Ghana

LB-5091

Intestinal Sampling: A Feasible Component of

Postmortem Minimally Invasive Tissue

Sampling (MITS) Procedures

Donna M. Denno1, Peter Finch2, Steve Kamiza3, Ta-

Chiang Liu4, Phillip I. Tarr4, Robert Bandsma5, Lisa A.

Niemann1, Wieger Voskuijl6 1University of Washington, Seattle, WA, United

States, 2University of Malawi, Blantyre,

Malawi, 3University of Malawi - College of Medicine,

Blantyre, Malawi, 4Washington University in St.

Louis, St. Louis, MO, United States, 5University of

Toronto, Toronto, ON, Canada, 6Amsterdam

University Medical Centres, Amsterdam, Netherlands

LB-5092

Expanded Access Program (EAP) to Provide

Stamaril® Vaccine to Persons traveling to

Yellow Fever Endemic Countries: One Center’s

Experience

Janak Koirala1, Abigail House1, Lori Miedwig1, Sana

Waqar1, Vidya Sundareshan1, Najwa Pervin1, Mary

Francine Chua1, Riyadh Muhammad2 1Southern Illinois University School of Medicine,

SPRINGFIELD, IL, United States, 2Sanofi Pasteur,

Swiftwater, PA, United States

LB-5093

Characterisation of Schistosoma

haematobium integral membrane proteins and

evaluation of their potential as novel diagnostic

markers

Gebeyaw Getnet Mekonnen1, Mark S Pearson1,

Luke Becker1, Abena S Amoah2, Govert van Dam3,

Paul L.A.M. Corstjens3, Takafira Mduluza4, Francisca

Mutapi5, Alex Loukas1, Javier Sotillo1 1Centre for Molecular Therapeutics, Australian

Institute of Tropical Health and Medicine, James

Cook University, Cairns, Australia, 2Department of

Parasitology, Leiden University Medical Center,

Leiden, Netherlands, 3Department of Molecular Cell

and Chemical Biology, Leiden University Medical

Center, Leiden, Netherlands, 4Biochemistry

Department, University of Zimbabwe, Mount

Pleasant, Harare, Zimbabwe, 5Institute of

Immunology & Infection Research, Ashworth

Laboratories, University of Edinburgh, King's

Buildings, Edinburgh, United Kingdom

LB-5094

Does parasitic meningitis without eosinophilia

in cerebrospinal fluid exist in northern

Vietnam?

Tomoko Hiraoka1, Chi Cuong Ngo2, Sugihiro

Hamaguch3, Mihoko Kikuchi4, Shungo Katoh5, Kim

Anh Le6, Thi Hien Anh Nguyen7, Duc Anh Dang7,

Chris Smith8, Lay-Myint Yoshida9, Cuong Do Duy2,

Thuy Pham Thanh2, Koya Ariyoshi1 1Department of Clinical Medicine, Institute of Tropical

Medicine (NEKKEN), Nagasaki University, Nagasaki,

Japan, 2Department of Infectious Diseases, Bach Mai

Hospital, Hanoi, Viet Nam, 3Department of General

Internal Medicine, Fukushima Medical University,

Fukushima, Japan, 4Department of Immunogenetics,

Institute of Tropical Medicine, Nagasaki University,

Nagasaki, Japan, 5Department of General Internal

Medicine, Nagasaki Rosai Hospital, Nagasaki,

Japan, 6Institute of Tropical Medicine, Nagasaki

University, Hanoi, Viet Nam, 7National Institute of

Hygiene and Epidemiology, Hanoi, Viet Nam, 8School

of Tropical Medicine and Global Health, Nagasaki

University, Nagasaki, Japan, 9Department of

Paediatric Infectious Diseases, Institute of Tropical

Medicine, Nagasaki, Japan

LB-5095

Soil-transmitted helminthiasis in Amazonian

Peru: a study comparing urban, suburban, and

rural prevalence and the efficacy of training

community health volunteers to use

smartphone-assisted-microscopy for point-of-

care diagnosis

Eve Ameen1, Simon Nin Zhu1, Cesar Morales

Guzman2, Erin Taub1, Crystyan Siles2, Graciela

Meza2, Stalin Vilcarromero1, Luis Marcos1 1Stony Brook University School of Medicine, Stony

Brook, NY, United States, 2Universidad Nacional de la

Amazonia Peruana, Iquitos, Peru

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21

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5096

Multidisciplinary management of hepatobiliary

ascariasis causing hepatic abscess, cholangitis,

and septic shock

Jonathan Steven Schultz, Tanit Phupitakphol,

Emily Warncke, Nathan Loudon, Nathan Loudon, Bill

Quach, Samuel Han, Augustin Attwell, Misha Huang,

Carlos Franco-Paredes

University of Colorado, Aurora, CO, United States

LB-5097

Treatment of Schistosomiasis in Pregnancy: A

Systematic Review of Maternal Outcomes

Alexandra Atayde1, Rachel Lau2, Melissa Phuong1,

Yashvi Bharwada1, Robert Chris1, Swana

Kopalakrishnan1, Swana Kopalakrishnan1, Leila

Makhani1, Sharmistha Mishra3, Andrea K. Boggild4 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Public Health Ontario

Laboratories, Toronto, ON, Canada, 3LI Ka Shing

Knowledge Institute, St. Michael's Hospital, Toronto,

ON, Canada, 4Tropical Disease Unit, Toronto General

Hospital and University of Toronto, Toronto, ON,

Canada

LB-5098

Angiostrongylus cantonensis infection linked to

ingestion of Kava

William L. Gosnell1, Gerald S. Murphy1, Johnnie A.

Yates2, Jourdan K. Posner1, Kenton J. Kramer1,

Elizabeth Blalock3, Vernon E. Ansdell1 1University of Hawai‘i at Mānoa, Honolulu, HI, United

States, 2Kaiser Permanente, Honolulu, HI, United

States, 3Spark M. Matsunaga VA Medical Center,

Honolulu, HI, United States

LB-5099

Rare case of an Australian

Parasite, Haycocknema perplexum, Infection

Presenting at a Large Reference Medical Center

in the Midwestern United States

Bobbi S. Pritt1, Blaine A. Mathison2, Richard

Bradbury3, John C. O'Horo1, David A. Grunst1, Lynne

M. Sloan1, Stefan Nicolau1, Amy Swanson1, Teerin

Liewluck1, Andrew Engel1, Abinash Virk1 1Mayo Clinic, Rochester, MN, United States, 2ARUP

Laboratories, Salt Lake Cities, UT, United

States, 3Slovak Tropical Institute, St. Elizabeth

University, Bratislava, Slovakia

LB-5100

Effect of prenatal exposure to urogenital

schistosomiasis on fetal immune responses

Indu Malhotra1, Ruth Nyakundi2, Ronald Ottichilo1,

Francis Mutuku3, A. Desiree LaBeaud4, Charles H.

King1 1Case Western Reserve University, Cleveland, OH,

United States, 2Institute of Primate Research,

Nairobi, Kenya, 3Technical University of Mombasa,

Mombasa, Kenya, 4Stanford School of Medicine,

Stanford, CA, United States

LB-5101

Intestinal parasites among school children

in southern Ethiopia: multilevel and zero-

inflated regression models

Hiwot Hailu1, Bernt Lindtjørn2 1Hawassa University, Hawassa, Ethiopia, 2University

of Bergen, Bergen, Norway

LB-5102

Test, Treat, Track, Test, and Treat (TTTTT)

Active Surveillance Towards Elimination of

Schistosomiasis: A Feasibility Study

Reda M. Ramzy1, Amal Rabiee2, Khaled M. Abd

Elaziz3, Carl H. Campbell, Jr4, Daniel G. Colley5, Ayat

A. Haggag6 1National Nutrition Institute, Cairo, Egypt, 2Ministry

of Health and population, Cairo, Egypt, 3Deaprtment

of Community, Environmental and Occupational

Medicine, Faculty of Medicine, Ain Shams University,

Cairo, Egypt, 4Center for Tropical and Emerging

Global Diseases, University of Georgia, Athens, GA,

United States, 5Department of Microbiology,

University of Georgia, and Center for Tropical and

Emerging Global Diseases, University of Georgia,

Athens, GA, United States, 6Ministry of Health and

Population, Cairo, Egypt

LB-5103

Using a novel multiplex bead assay integrating

serologic reactivity to leprosy and endemic

helminths to uncover a hidden burden of NTDs

in eastern Minas Gerais, Brazil

Jessica K. Fairley1, Gretchen Cooley2, Lorena B.

Oliveira3, José A. Ferreira4, Malcolm S. Duthie5,

Diana Martin2, W. Evan Secor2, Lucia A. Fraga3 1Emory University School of Medicine, Atlanta, GA,

United States, 2Centers for Disease Control and

Prevention, Atlanta, GA, United States, 3Universidade

Federal de Juiz de Fora – Campus GV, Governador

Valadares, Brazil, 4Faculdade da Saúde e Ecologia

Humana, Vespasiano, Brazil, 5Infectious Disease

Research Institute, Seattle, WA, United States

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22

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5104

Innovative Approach for Community

Engagement for Kala-Azar Prevention and

Treatment in Low Resource Settings: An

Experience from Two Endemic States in Eastern

India

Rajshree Das, Sudipta Mondal

Project Concern International, New Delhi, India

LB-5105

Integrated eye care workers’ surgical output

within the Ministry of Health’s Fast Track

Initiative against trachoma in Amhara region,

Ethiopia

Begashaw Hailemariam1, Eshetu Sata1, Mulat

Zerihun1, Kimberly A. Jensen2, Scott D. Nash2,

Melkamu Beyene3, Wim Adriaensen4, Philip Owiti5,

Mbazi Senkoro6, Zerihun Tadesse1, Maria Zolfo4 1The Carter Center, Addis Ababa, Ethiopia, 2The

Carter Center, Atlanta, GA, United States, 3Amhara

Regional Health Bureau, Bahir Dar,

Ethiopia, 4Institute of Tropical Medicine, Antwerp,

Belgium, 5The International Union against TB & Lung

Disease, Paris, France, 6National Institute for Medical

Research-Muhimbili Center, Dar es Salaam,

Tanzania, United Republic of

LB-5106

COMPARATIVEANALYSISOF CLINICAL DATA IN

NEW BORN WITH CHAGAS BETWEEN TWO

PERIODS OF TIME IN BOLIVIA

Freddy Tinajeros1, Maria del Carmen Menduiña2,

Maritza Calderon3, Jean Karla Velarde1, Clariza

Chavez1, Edith Malaga3, Natalie Bowman4, Manuela

Verastegui3, Robert Gilman5 1PRISMA - John Hopkins University, Santa Cruz,

Bolivia, Plurinational State of, 2Ministry of Health,

Bolivia, Santa Cruz, Bolivia, Plurinational State

of, 3Universidad Peruana Cayetano Heredia, Lima,

Peru, 4North Caroline University, Santa Cruz, NC,

United States, 5John Hopkins University, Baltimore,

MD, United States

LB-5107

Feasibility assessment of a Test-Treat-Track-

Test-Treat strategy for schistosomiasis control

in low prevalence areas in North western

Tanzania

Jane K. Maganga1, Safari M. Kinung'hi1, Teckla

Angelo1, Joseph Mwanga2, Justina Mosha1, Carl

Campbell3

1National Institute for Medical Research (NIMR),

Mwanza, Tanzania, United Republic of, 2Catholic

University of Health and Allied Sciences (CUHAS),

Mwanza, Tanzania, United Republic of, 3Center for

Tropical and Emerging Global Diseases, University of

Georgia, Athens, GA, United States

LB-5108

Bioefficacy Evaluation of a Metofluthrin

Emanator as Protection Against Aedes

albopictus

Olivia Zarella1, Oscar Kirstein1, Uchechukwu

Ekwomadu1, Yamila Romer1, Gregor Devine2, Pablo

Manrique-Saide3, Gonzalo Vazquez-Prokopec1 1Emory University, Atlanta, GA, United States, 2QIMR

Berghofer Medical Research Institute, Brisbane,

Australia, 3Universidad Autonoma de Yucatan,

Yucatan, Mexico

LB-5109

An epidemiological study of Shistosomiasis

infection and its correlates among school aged

children in Senegal, Mali, Guinea and

Mauritania

Roger C. TINE, Adama FAYE, Doudou Sow, Malang

Mane, Khadime Sylla, Mame Venuse Badiane,

Magatte Ndiaye, Babacar Faye

University Cheikh Anta Diop, Senegal, Dakar,

Senegal

LB-5110

Development of quality standards and quality

assurance program for malaria molecular

diagnostic & genotyping assays

Zhiyong Zhou1, Rispah Abdallah2, Dragan Ljolje1,

Amy S. Kong1, Samaly S. Svigel1, Douglas Nace1, Ya

Ping Shi1, Venkatachalam Udhayakumar1, Naomi

Lucchi1 1Centers for Disease Control and Prevention, Atlanta,

GA, United States, 2Oak Ridge Institute for Science

and Education, Oak Ridge, GA, United States

LB-5111

Evaluating parasite viability after

administration of a novel antimalarial drug

candidate in the induced blood stage malaria

model

Maria Rebelo1, David S. Khoury2, Jeremy Gower1,

Rebecca Pawliw1, Lachlan Webb1, Zuleima Pava1,

Rebecca Webster1, Miles P. Davenport2, James S.

McCarthy1 1QIMR Berghofer Medical Research Institute,

Brisbane, Australia, 2Kirby Institute UNSW, Sydney,

Australia

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23

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5112

Assessment of Severe Malaria Treatment

Practices and Challenges in Southern Tanzania

2019

Joseph MUGASA1, Abdallah Lusasi2, Mustafa Njozi3,

Issa Garimo2, Faustin Rwegobora4, Jongo Machage4,

Godlove Mkumbo4, Neema Machumu4, Lameck

Maganga4, John Gamaliel1, Khanga Jairi5, Carlton

Jones3, Erik Reaves6, Jema Bisimba7, Chonge Kitojo8,

Emeka Okechukwu1, Halima Mwenesi9, Marina

Njelekela3 1FHI360, Dar es Salaam, Tanzania, United Republic

of, 2National Malaria Control Program (NMCP),

Dodoma, Tanzania, United Republic of, 3Deloitte

Consulting Ltd, Dar es Salaam, Tanzania, United

Republic of, 4Management and Development for

Health (MDH), Dar es Salaam, Tanzania, United

Republic of, 5Regional Referral Hospital, Ruvuma,

Tanzania, United Republic of, 6US President's Malaria

Initiative/Centers for Disease Control & Prevention,

Dar es Salaam, Tanzania, United Republic of, 7United

States Agency for International Development

(USAID), Dar es Salaam, Tanzania, United Republic

of, 8US President's Malaria Initiative/United States

Agency for International Development, Dar es

Salaam, Tanzania, United Republic of, 9FHI360,

Washington, DC, United States

LB-5113

Detection of Plasmodium falciparum by light

microscopy, Loop Mediated Isothermal

Amplification, and PCR on day 3 after initiation

of artemether-lumefantrine treatment for

uncomplicated malaria in Bagamoyo District,

Tanzania - a comparative trial

Lwidiko E. Mhamilawa1, Berit A. Schmidt2, Ulrika

Morris2, Bruno Mbando3, Billy Ngasala4, Andreas

Mårtensson1 1Uppsala University, UPPSALA, Sweden, 2Karolinska

Institutet, Stockholm, Sweden, 3National Institute for

Medical Research,Tanga Centre, Tanga, Tanzania,

United Republic of, 4Muhimbili University of Health

and Allied Sciences, Dar es Salaam, Tanzania, United

Republic of

LB-5114

Characterising the effect of a delayed fractional

dosing regimen on the humoral responses

induced by the Plasmodium falciparum Blood-

Stage Vaccine RH5.1/AS01B

Jordan R. Barrett1, Sarah E. Silk1, Angela M.

Minassian1, Carolyn M. Nielsen1, Kazutoyo Miura2,

Ababacar Diouf2, Ruth O. Payne1, Nick J. Edwards1,

Katherine J. Ellis1, Doris Quinkert1, Yrene

Themistocleous1, Thomas A. Rawlinson1, Ian D.

Poulton1, Celia H. Mitton1, Antonio Querol-Rubiera3,

Karen Bisnauthsing3, Tatiana Ongrina4, Rahul Batra3,

Nathan J. Brendish4, Megan Baker1, Raquel L.

Ramon1, Fernando R. Lopez1, Lea Barfod1, Pedro M.

Folegatti1, Daniel Silman1, Mehreen Datoo1, Iona J.

Taylor1, Jing Jin1, David Pulido-Gomez1, Willem A. de

Jong5, Robert Smith6, Eleanor Berrie6, Danielle

Morelle7, Marc Lievens7, Amy R. Noe8, Carter L.

Diggs9, Lorraine A. Soisson9, Rebecca Ashfield1, Saul

N. Faust4, Anna L. Goodman3, Alison M. Lawrie1, Fay

L. Nugent1, Carole A. Long2, Simon J. Draper1 1Jenner Institute, University of Oxford, Oxford,

United Kingdom, 2Laboratory of Malaria and Vector

Research, NIAID/NIH, Rockville, MD, United

States, 3Guy’s and St. Thomas’ Hospital NHS Trust,

London, United Kingdom, 4NIHR Wellcome Trust

Clinical Research Facility, University Hospital

Southampton NHS Foundation Trust Faculty of

Medicine, University of Southampton, Southampton,

United Kingdom, 5ExpreS2ion Biotechnologies,

SCION-DTU Science Park, Agern Allé 1, Hørsholm,

Denmark, 6Clinical BioManufacturing Facility,

University of Oxford, Oxford, United Kingdom, 7GSK

Vaccines, Wavre, Belgium, 8Leidos Life Sciences,

Frederick, MD, United States, 9Malaria Vaccine

Development Program, United States Agency for

International Development (USAID), Washington,

DC, United States

LB-5115

Malaria surveillance on paper: a cost-effective,

field-adaptable Plasmodium circumsporozoite

ELISA

Haley E. Stephens1, Maria Andrea Eula1, Iris Beatriz

Erramuspe1, Diego Gómez Maldonado1, Alice C.

Sutcliffe2, Ellen M. Dotson2, Maria Soledad Peresin1,

Sarah Zohdy1 1Auburn University, Auburn, AL, United

States, 2Centers for Disease Control and Prevention,

Atlanta, GA, United States

LB-5116

Ink-jet printable malaria surveillance: a

sustainable, cost effective circumsporozoite

detection assay

Maria Andrea Camarano Eula1, Haley Stephens1,

Iris Beatriz Vega Erramuspe1, Diego Gómez

Maldonado1, Alice C. Sutcliffe2, Ellen M. Dotson2,

Maria Soledad Peresin1, Sarah Zohdy1 1Auburn University, Auburn, AL, United

States, 2Centers for Disease Control and Prevention,

Atlanta, GA, United States

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24

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5117

Autoencoder and Artificial Neural Networks

Applied to Near-infrared Spectra to Estimate

Parity Status of Wild An. gambiae s.s and An.

arabiensis

Masabho P. Milali1, Samson S. Kiware1, Sedar

Bozdag2, Naveen Bansal1, Jacques D. Charlwood3,

Floyd E. Dowell4, George F. Corliss5, Maggy T.

Sikulu-Lord6, Richard J. Povinelli5 1Department of Mathematical and Statistical

Sciences, Marquette University, Milwaukee, WI,

United States, 2Department of Computer Science,

Marquette University, Milwaukee, WI, United

States, 3Liverpool School of Tropical Medicine,

Liverpool, United Kingdom, 4USDA, Agricultural

Research Service, Center for Grain and Animal

Health Research, Manhattan, KS, United

States, 5Department of Electrical and Computer

Engineering, Marquette University, Milwaukee, WI,

United States, 6Queensland Alliance of Agriculture

and Food Innovation, The university of Queensland,

Brisbane, Australia

LB-5118

Malaria Hospitalization Patterns in Central and

Southern Malawi Among Children Ages 5-48

Months

Hillary M. Topazian1, Mallory Michalak2, Don

Mathanga3, Madalitso Zulu2, Harrison Msuku3,

Lusungu Msumba2, Jonathan J. Juliano1, Irving

Hoffman1, Jobiba Chinkhumba3, Vincent S. Phiri3,

Davie Kondowe2, Kelvin Maziya2, Enala Mzembe3,

Betty Kazanga3, Tisungane Mvalo2 1University of North Carolina at Chapel Hill, Chapel

Hill, NC, United States, 2University of North Carolina

Project Malawi, Lilongwe, Malawi, 3University of

Malawi, College of Medicine, Malaria Alert Center,

Blantyre, Malawi

LB-5119

Challenges in Developing a Hospital-Based

Malaria Surveillance Program

Madalitso Zulu1, Mallory Michalak1, Don Mathanga2,

Hillary M. Topazian3, Lusungu Msumba1, Jonathan J.

Juliano3, Irving Hoffman3, Jobiba Chinkhumba2,

Harrison Msuku2, Vincent S. Phiri2, Davie Kondowe1,

Kelvin Maziya1, Enala Mzembe2, Betty

Kazanga2, Tisungane Mvalo1 1University of North Carolina Project Malawi,

Lilongwe, Malawi, 2University of Malawi, College of

Medicine, Malaria Alert Center, Blantyre,

Malawi, 3University of North Carolina at Chapel Hill,

Chapel Hill, NC, United States

LB-5120

Accelerated Stability Study of Pfs230D1M-EPA

Conjugate

Daming Zhu, Alec Allee-Munoz, Weili Dai, Holly

McClellan, Karine Reiter, Lynn Lambert, Emma

Barnafo, Kelly M. Rausch, David L. Narum, Patrick E.

Duffy

Laboratory of Malaria Immunology and Vaccinology,

Bethesda, MD, United States

LB-5121

Association between anemia and gametocyte

carriage in uncomplicated malaria patients

living in endemic area of Burkina Faso

San Maurice Ouattara, Noëlie Henry, Amidou

Diarra, Sam Aboubacar Coulibaly, Tanga Jean

Kaboré, Benjamin Sombié, Amidou Z. Ouédraogo,

Alphonse Ouédraogo, Alfred B. Tiono, Issiaka

Soulama, Sodiomon Bienvenu Sirima

Centre National de Recherche et de Formation sur le

Paludisme, Ouagadougou, Burkina Faso

LB-5122

Improvement of good quality standard

practices for genotyping in antimalarial drug

clinical trials

Christian Nsanzabana, Astrid Mattes, Desirée

Eckert, Maura Concu, Carla Beuret, Ksenija Kocur,

Sven Poppert, Daniel Paris, Hans-Peter Beck

Swiss Tropical and Public Health Institute, Basel,

Switzerland

LB-5123

Durability Monitoring of Long-Lasting

Insecticidal Nets in Malaria-Endemic Regions of

Zimbabwe

Ekpenyong E. Ekanem1, Patrick Chinyamuchiko2,

Martin Netsa2, Peter Troell3, Regis Magauzi1, Christie

Billingsley4, Wilson Chauke5, Joseph Mberikunashe5 1Abt Associates Inc., Rockville, MD, United

States, 2ZAPIM/Abt Associates Inc., Harare,

Zimbabwe, 3U.S. President's Malaria

Initiative/Centers for Disease Control and

Prevention, Harare, Zimbabwe, 4U.S. President’s

Malaria Initiative, Harare, Zimbabwe, 5National

Malaria Control Program, Ministry of Health and Child

Care, Harare, Zimbabwe

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25

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5124

Identifying and testing the attractiveness of

chemical compounds from mango juice that

attract malaria vectors in toxic sugar bait

Felician C. Meza1, Joe Roberts2, Islam S. Sobhy2,

Sarah J. Moore1, Fredros O. Okumu1, Toby J. Bruce2,

Frederic Tripet2 1Ifakara Health Institute, Ifakara, Morogoro,

Tanzania, United Republic of, 2Keele University,

Newcastle, United Kingdom

LB-5125

P. falciparum gametocyte infectivity in two

ethnic group Fulani and Mossi groups living in

Burkina Faso: a comparative study

Samuel Sindié Sermé1, Noelie Henry/Béré1, Salif

Sombié1, Amidou Diarra1, Désiré Kargougou1,

Benjamin S. Sombié1, Moussa W. Guelbeogo1, Issa

N. Ouedraogo1, David Modiano2, Alfred Tiono1, Edith

C. Bougouma1, Yves Traore3, Issiaka Soulama1,

Sodiomon B. Sirima1 1Centre National de Recherche et de Formation sur le

Paludisme (CNRFP), Ouagadougou, Burkina

Faso, 2University La Sapienza at Roma, Roma, Italia,

Burkina Faso, 3University JKZ at Ouagadougou,

Ouagadougou, Burkina Faso

LB-5126

Comparison of capillary versus venous blood

for the detection of Plasmodium falciparum

malaria using rapid diagnostic tests.

Abalinda M. Gorret1, Rabbison Muhindo1, Michael

Matte1, Dan Nyehange2, Ntaro Moses1, Edgar M.

Mulogo1, Ross M. Boyce3 1Mbarara University of Science and Technology,

Mbarara, Uganda, 2Epicentre Research Base,

Mbarara, Uganda, 3University of North Carolina at

Chapel Hill, Chapel Hill, NC, United States

LB-5127

Physical & Biological Durability of Long Lasting

Insecticidal Nets in Ethiopia: A 3-Year

Longitudinal Study

Honelgn Nahusenay Hiruy1, Ayele Zewde2, Yonas

Wuletaw3, Seth Irish4, Semira Abdelmenan2,

Gunawardena Dissanayake5, Matthew Murphy5,

Sheleme Chibsa5, Hiwot Solomon6, Alemayehu

Worku2, Yemane Berhane2, Joseph Keating1 1Tulane University, New Orleans, LA, United

States, 2Addis Continental Institute of Public Health,

Addis Ababa, Ethiopia, 3Ethiopian Public Health

Institute, Addis Ababa, Ethiopia, 4Entomology

Branch, Division of Parasitic Diseases and Malaria,

Center for Global Health, Centers for Disease Control

and Prevention and U.S. President’s Malaria

Initiative, Atlanta, GA, United States, 5U.S.

President’s Malaria Initiative, Addis Ababa,

Ethiopia, 6National Malaria Prevention, Control and

Elimination Program, Addis Ababa, Ethiopia

LB-5128

Reactive focal mass drug administration at

household level does not have community-wide

impact on malaria burden in a pre-elimination

setting in southern Mozambique

Julia Montana Lopez1, Humberto Munguambe2,

Beatriz Galatas1, Lidia Nhamussua2, Wilson Simone2,

Fernando Laice2, Felimone Amone2, Regina

Rabinovich3, Fabiao Luis2, Francisco Saute2, Pedro

Aide4, Caterina Guinovart5 1Barcelona Institute for Global Health - Centro de

Investigaçao em Saude de Manhiça, Manhiça,

Mozambique, 2Centro de Investigaçao em Saude de

Manhiça, Manhiça, Mozambique, 3Barcelona Institute

for Global Health - Harvard TH Chan School of Public

Health, Boston, MA, United States, 4Centro de

Investigaçao em Saude de Manhiça - National

Malaria Control Program, Ministry of Health, Maputo,

Mozambique, 5Barcelona Institute for Global Health,

Barcelona, Spain

LB-5129

Malaria Border facilities as an intervention to

prevent cross-border malaria transmission by

migrant and mobile populations (MMPs) in

Kavango West Region, Namibia

Davis R. Mumbengegwi1, Tanga Kashupi1,

Iwanette Du Preez1, Hans Amukugo1, Jerobeam

Hamunyela2, Mukosha Chisenga3, Immo

Kleinschmidt3, Petrina Uusiku2 1University of Namibia, Windhoek, Namibia, 2Namibia

National Vector-Borne Disease Control Programme,

Windhoek, Namibia, 3SADC Malaria Elimination 8,

Windhoek, Namibia

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26

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5130

Dual-targeting antimalarial agents with multi-

lifecycle stage disruption of parasite egress and

invasion

Alan F. Cowman1, Justin A. Boddey1, Janni

Christensen1, Manuel de Lera Ruiz2, Melanie H.

Dietrich1, Paola Favuzza1, Kai-Yuan Guo1, Zhuyan

Guo2, Julie Healer1, Bin Hu3, Mengwei Hu2, Kate

Jarman1, Helene Jousset Sabroux1, Tanweer Khan2,

Zhiyu Lei2, Sash Lopaticki1, John A. McCauley2,

Randy R. Miller2, Nicholas Murgolo2, Anna Ngo1, Tony

Papenfuss1, Jocelyn Penington1, Kitsanapong

Reaksudsan1, Jonathan A. Robbins2, Brad E. Sleebs1,

Ryan W. Steel1, Wai-Hong Tham1, Jennifer

Thompson1, Tony Triglia1, Marissa Vavrek2, Dongmei

Zhan3, Lianyun Zhao2, David B. Olsen2 1The Walter and Eliza Hall institute of Medical

Research, Parkville, Australia, 2Merck and Co Inc,

West Point, PA, United States, 3WuXi AppTec,

Shanghai, China

LB-5131

High throughput isolation of vaccine-grade

malaria sporozoites from whole mosquitoes

without dissection

Joshua Blight1, Erwan Atcheson2, Katarzyna A.

Sala1, Holger Kramer1, Aadil El-Turabi2, Eliana Real1,

Farah Dahalan1, Paulo Bettencourt2, Emma

Dickinson2, Eduardo Alves1, Ahmed M. Salman3,

Shahid M. Khan4, Chris J. Janse4, Frances Ashcroft5,

Adrian V. Hill2, Andrew Blagborough6, Arturo Reyes-

Sandoval7, Jake Baum1 1Imperial College London, London, United

Kingdom, 2Jenner Institute, University of Oxford,

Oxford, United Kingdom, 3Jenner Institute, University

of Oxford, London, United Kingdom, 4Leiden Malaria

Research Group, Leiden, Netherlands, 5University of

Oxford, Oxford, United Kingdom, 6University of

Cambridge, Cambridge, United Kingdom, 7Jenner

Institute, University of Oxfrod, Oxford, United

Kingdom

LB-5132

Human antibody repertoires to RIFINs and

STEVORs associate with reduced risk to febrile

malaria

Bernard N. Kanoi1, Hikaru Nagaoka1, Nirianne M.

Q. Palacpac2, Michael T. White3, Masayuki Morita1,

Edward H. Ntege4, Betty Balikagala5, Adoke Yeka6,

Thomas G. Egwang7, Toshihiro Horii2, Takafumi

Tsuboi1, Eizo Takashima1 1Division of Malaria Research, Proteo-Science Center,

Ehime University, Matsuyama, Japan, 2Department

of Molecular Protozoology, Research Institute for

Microbial Diseases, Osaka University, Osaka,

Japan, 3Department of Parasites and Insect Vectors,

Pasteur Institute, Paris, France, 4Department of

Plastic and Reconstructive Surgery, University of the

Ryukyus School of Medicine and Hospital, Okinawa,

Japan, 5Department of Tropical Medicine and

Parasitology, School of Medicine, Juntendo

University, Tokyo, Japan, 6Makerere University

School of Public Health, Kampala, Uganda, 7Med

Biotech Laboratories, Kampala, Uganda

LB-5133

Bioanalysis of primaquine and

carboxyprimaquine in plasma, breast milk and

dry blood spots

Warunee Hanpithakpong, Nicholas. P.J. Day,

Nicholas. J. White, Joel Tarning

Mahidol-Oxford Tropical Medicine Research Unit,

Rajivithi, Thailand

LB-5134

Efficacy of artemether-lumefantrine for the

treatment of uncomplicated Plasmodium

falciparum infection in Rwanda, 2018

Aline Uwimana1, Noella Umulisa2, Eric S. Halsey3,

Meera Venkatesan4, Tharcisse Munyaneza5, Rafiki M.

Habimana6, Ryan Sandford7, Leah Moriarty3, Emily

Piercefield8, Zhiyong Zhou3, Samaly Souza3, Naomi

Lucchi3, Daniel Ngamije9, Jean-Louis N. Mangala1,

William Brieger10, Venkatachalam Udhayakumar3,

Aimable Mbituyumuremyi1 1Malaria and Other Parasitic Diseases Division,

Rwanda Biomedical Centre, Kigali,

Rwanda, 2Maternal and Child Survival Program,

JHPIEGO, Baltimore, MD, United States, 3Malaria

Branch, Centers for Disease Control and Prevention,

Atlanta, GA, United States, 4US President’s Malaria

Initiative, Washington, DC, United States, 5National

Reference Laboratory, Rwanda Biomedical Centre,

Kigali, Rwanda, 6National Reference Laboratory,

Rwanda Biomedical Centre, Kigali, Rwanda, 7US

Peace Corps, Kigali, Rwanda, 8Malaria Branch,

Centers for Disease Control and Prevention, Kigali,

Rwanda, 9WHO Rwanda Office, Malaria and

Neglected Tropical Diseases Programs, Kigali,

Rwanda, 10The Johns Hopkins University, Bloomberg

School of Public Health, Department of International

Health, Baltimore, MD, United States

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27

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5135

Novel oral vaccine platform: Marine

protozoan Perkinsus marinus successfully

expressed full length Plasmodium

falciparum Circumsporozoite protein (PfCSP)

vaccine

Raghavendra Yadavalli1, Hannah Waugh2, Sofia

Casares3, Jose Antonio Robledo1 1Bigelow Laboratory for Ocean Sciences, East

Boothbay, ME, United States, 2Southern Maine

Community College, South Portland, ME, United

States, 3Naval Medical Research Center, Silver

Spring, MD, United States

LB-5136

Protocol for randomised controlled trial to

measure the mosquitocidal effect and

pharmacokinetics of different ivermectin dose

regimens in African individuals

Marta Ferreira Maia1, Carlos Chaccour2, Felix

Hammann3, Urs Duthaler4, Jonathan Karisa5, Martha

Muturi5, Mainga Hamaluba5, Simon Muriu6, Regina

Rabinovich2 1University of Oxford, Oxford, United Kingdom, 2IS

Global, Barcelona, Spain, 3University Hospital of

Bern, Bern, Switzerland, 4University of Basel, Basel,

Switzerland, 5KEMRI Wellcome Trust Research

Programme, Kilifi, Kenya, 6Pwani University, Kilifi,

Kenya

LB-5137

Do current interventions adequately protect at-

risk populations in high-burden malaria zones?

Continuing Malaria Transmission in Angwa

Ward, Mbire District, Mashonaland Central

Province, Zimbabwe

Fortunate Manjoro1, Joseph Mberikunashe1,

Christie Billingsley2, Regis Magauzi2, Patrick

Chinyamuchiko3, Gilson Mandigo4, Hieronymo

Masendu1, Cecilia Mhiti3, Ekpenyong E. Ekanem5 1National Malaria Control Programme, Ministry of

Health and Child Care, Harare, Zimbabwe, 2U.S.

President’s Malaria Initiative, Harare,

Zimbabwe, 3ZAPIM/Abt Associates Inc., Harare,

Zimbabwe, 4ZAPIM/Jhpiego, Harare, Zimbabwe, 5Abt

Associates Inc., Rockville, MD, United States

LB-5138

Testing the prophylactic and therapeutic effects

of von Willebrand factor inhibition on severe

malaria in rhesus macaques

Noppon Popruk1, Manutsanun Sumonwiriya1,

Katarina Kovacevic2, Sujitra Tayamun1, Laksanee

Inamnuay1, Rawiwan Im-erbsin1, Matthew D.

Wegner1, Matthew C. Reed1, Luis A. Lugo-Roman1,

Shuhao Zhu3, James C. Gilbert3, Bernd Jilma2,

Piyanate Sunyakumthorn1 1Armed Forces Research Institute of Medical

Sciences, Bangkok, Thailand, 2Medical University of

Vienna, Vienna, Austria, 3Band Therapeutics LLC,

Belmont, MA, United States

LB-5139

Multidrug-resistant genotypes are associated

with therapeutic failure of dihydroartemisinin-

piperaquine therapy in Cambodia, a

pharmacometric approach

Richard M. Hoglund1, Chanaki Amaratunga2,

Sokunthea Sreng3, Pharath Lim4, Seila Suon5,

Nicholas P. Day2, Nicholas J. White2, Rick Fairhurst4,

Joel Tarning1 1Department of Clinical Pharmacology, Mahidol

Oxford Tropical Medicine Research Unit, Bangkok,

Thailand, 2Mahidol Oxford Tropical Medicine Research

Unit, Bangkok, Thailand, 3) National Center for

Parasitology, Entomology, and Malaria Control,

Phnom Penh, Cambodia, 4Laboratory of Malaria and

Vector Research, National Institute of Allergy and

Infectious Diseases, National Institutes of Health,

Bethesda, MD, United States, 5National Center for

Parasitology, Entomology, and Malaria Control,

Phnom Penh, Cambodia

LB-5140

Development and evaluation of a field-

deployable whole parasite blood-stage malaria

vaccine in a rodent model of malaria

Danielle I. Stanisic1, Mei-Fong Ho1, Emily Cooper1,

Reshma Nevagi1, Waleed M. Hussein2, Mariusz

Skwarczynski2, Istvan Toth2, Michael F. Good1 1Institute for Glycomics, Griffith University,

Southport, Australia, 2School of Chemistry and

Molecular Biosciences, The University of Queensland,

Brisbane, Australia

LB-5141

Commercial host biomarker based diagnostics

to differentiate between bacterial and non-

bacterial infections in a highly malaria endemic

setting in Malawi

Sabine Dittrich1, Victoria Harris1, Camille

Escadafal1, Ben Chilima2, Jullita Malava3, Louis

Banda3, Hazzie Mvula3, Watipasa Kasambara2, Mia

Crampin3, Sue J. Lee1, Aurélien Mace1, Leticia

Fernandez1, Steffen Geis3 1Foundation for Innovative New Diagnostics (FIND),

Geneva, Switzerland, 2Community Health Science

Unit (MoH), Lilongwe, Malawi, 3Malawi Epidemiology

and Intervention Research Unit, Karonga, Malawi

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28

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5142

Assessment of artemisinin resistance genetic

background mutations in P. falciparumin Mali.

A tool to predict Artemisinin resistance

emergence

Seidina A. S. Diakite1, Ibrahima Sanogo1, Drissa S.

Konate1, Karim Traore1, Antoine Dara1, Djeneba

Dabitao1, Amadou Cisse1, Fousseny Doucoure1,

Modibo Sangare1, Gordon A. Awandare2, Mahamadou

Diakite1 1MRTC/USTTB, Bamako, Mali, 2WACCBIP/Uiversity of

Ghana, Legon, Accra, Ghana

LB-5143

Severe malaria in iron deficient children is

associated with oxidative stress

Daniel B. Blatt1, Ian C. Michelow1, Katrina Co2,

Dibyadyuti Datta2, Robert O. Opoka3, Sarah E.

Cusick4, Chandy C. John2 1Brown University/Hasbro Children's Hospital,

Providence, RI, United States, 2Indiana University

School of Medicine, Indianapolis, IN, United

States, 3Makerere University, Kampala,

Uganda, 4University of Minnesota, Minneapolis, MN,

United States

LB-5144

Diagnostic accuracy of the Infection Manager

System (IMS) compared to C-reactive protein

and procalcitonin to detect bacteraemia and

malaria-bacterial co-infections among children

and adults in Burkina Faso

Annelies Post1, Berenger Kaboré2, Joel Bognini2,

Salou Diallo2, Palpouguini Lompo2, Basile Kam2,

Natacha Herssens3, Fred van Opzeeland1, Christa van

Ghaast1, Jeroen Langereis1, Marien de Jonge1,

Jeanette Rahamat-Langendoen1, Teun Bousema1,

Heiman Wertheim1, Robert Sauerwein1, Halidou

Tinto2, Jan Jacobs3, Quirijn de Mast1, Andre J. van

der Ven1 1Radboud university medical centre, Nijmegen,

Netherlands, 2IRSS/Clinical Research Unit of Nanoro

(CRUN), Nanoro, Burkina Faso, 3Department of

Clinical Sciences, Institute of Tropical Medicine

(ITM), Antwerp, Belgium

LB-5145

Thrombocytopenia and Whole Blood

Transfusion in Children with Severe Malarial

Anemia

Matthew M. Ippolito1, Jean-Bertin Kabuya2,

Manuela Hauser3, Benjamin Kussin-Shoptaw4, Austin

Peer1, Albert Baschong5, Marco Ruegg5, Luc K.

Kamavu6, Thomas A. Louis4, William J. Moss4 1Johns Hopkins University School of Medicine,

Baltimore, MD, United States, 2Tropical Diseases

Research Centre, Ndola, Zambia, 3University

Children's Hospital, Zurich, Switzerland, 4Johns

Hopkins University School of Public Health,

Baltimore, MD, United States, 5University of Basel,

Basel, Switzerland, 6St. Paul's Mission General

Hospital, Nchelenge, Zambia

LB-5146

High incidence and case fatality of severe and

complicated malaria in the pediatric emergency

department of the Gabriel Toure University

hospital of Bamako, Mali

Abdoul Aziz Diakite1, Belco Maiga1, Adama Dembele1,

Fatoumata Dicko Traore1, Mariam Sylla1, Seydou

DOUMBIA2 1University Hospital Gabriel Toure, Bamako,

Mali, 2University Clinical Research Center, Point G,

Bamako, Mali

LB-5147

Vector control response post cyclone in

Mozambique

Baltazar Candrinho1, Abraham Mnzava2, Eva de

Carvalho3, Rose Zulliger4, Molly Robertson5 1National Malaria Control Program, Ministry of

Health, Maputo, Mozambique, 2African Leaders

Malaria Alliance, New York City, NY, United

States, 3Malaria Programme, World Health

Organization Regional Office for Africa, Maputo,

Mozambique, 4US President’s Malaria Initiative and

Malaria Branch, Division of Parasitic Diseases and

Malaria, US Centers for Disease Control and

Prevention, Maputo, Mozambique, 5PATH,

Washington, DC, United States

LB-5148

A Single Dose of the MVA-BN Smallpox Vaccine

Induces an Early Protective Antibody Response

Similar to a Traditional Replicating Vaccine and

is a Potential Vaccine for Monkeypox

Heinz Weidenthaler1, Phillip R. Pittman2, Jack

Stapleton3, Darja Schmidt1, Jane Maclennan1, Paul

Chaplin4 1Bavarian Nordic, Martinsried, Germany, 2United

States Army Medical Research Institute of Infectious

Diseases, Fort Detrick, MD, United

States, 3University of Iowa, Iowa City, IA, United

States, 4Bavarian Nordic, Kvistgard, Denmark

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29

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5149

Incidence of acute Q fever and spotted fever

group rickettsioses, Kilimanjaro, Tanzania,

2007-2008 and 2012-2014

Sruti Pisharody1, Matthew P. Rubach1, William L.

Nicholson2, Jamie L. Perniciaro2, Manuela Carugati1,

Holly M. Biggs1, Michael J. Maze3, Julian T. Hertz1, Jo

E. Halliday4, Kathryn J. Allan4, Blandina T. Mmbaga5,

Wilbrod Saganda5, Bingileki F. Lwezaula6, Rudovick

R. Kazwala7, Sarah Cleaveland4, Venance P. Maro5,

John A. Crump1 1Duke University, Durham, NC, United

States, 2Centers for Disease Control and Prevention,

Atlanta, GA, United States, 3University of Otago,

Dunedin, New Zealand, 4University of Glasgow,

Glasgow, United Kingdom, 5Kilimanjaro Christian

Medical Centre, Moshi, Tanzania, United Republic

of, 6Mawenzi Regional Referral Hospital, Moshi,

Tanzania, United Republic of, 7Sokoine University of

Agriculture, Morogoro, Tanzania, United Republic of

LB-5150

Detecting low frequency antigen-specific cells

and their cytokine profile by flow cytometry

Marie Mura1, Elizabeth Duncan1, Kevin Beck2, Elke

Bergmann-Leitner1 1WRAIR, Silver Spring, MD, United States, 2Lentigen

Technology, Gaithersburg, MD, United States

LB-5151

Policy Challenges and Recommendations for

Gene Drives Beyond Malaria

Kelsey Lane Warmbrod, Amanda L. Kobokovich,

Rachel West, Georgia Ray, Marc Trotochaud, Marc

Trotochaud, Michael Montague, Anita Cicero, Tom

Inglesby

Johns Hopkins Center for Health Security, Baltimore,

MD, United States

LB-5152

Foodborne Zoonotic Risk factors Associated

with Self-Reported Illness Somali Region,

Ethiopia, 2016 and 2017

Lindsay C. Morton1, Julie Davis1, Nicolette Bestul1,

Farah Mussa Hosh2, Lauren Carruth3, Amira Roess1 1Milken Institute School of Public Health, George

Washington University, Washington, DC, United

States, 2Animal Population Health Institute, College

of Veterinary Medicine and Biomedical Sciences,

Colorado State University, Fort Collins, CO, United

States, 3School of International Service, American

University, Washington, DC, United States

LB-5153

Clinical features of alveolar echinococcosis, an

emerging infectious disease in Alberta, Canada

Stan Houston1, Sara Belga2, Clayton MacDonald1,

Safwat Girgis1, Bruno Gottstein3, Alessandro

Massolo4, Klaus Buttenschoen1, Jutta Preiksaitis1,

Ryan Cooper1, Philippe Sarlieve1, Gavin Low1,

Norbert Muller3, Steven Vaughan5, Kinga

Kowalewska-Grochowska1 1University of Alberta, Edmonton, AB,

Canada, 2University of British Colombia, Vancouver,

BC, Canada, 3Institute of Parasitology, Bern,

Switzerland, 4University of Pisa, Pisa,

Italy, 5University of Calgary, Calgary, AB, Canada

LB-5154

KNOWLEDGE, ATTITUDES, RISK PERCEPTION

AND PREPAREDNESS OF HEALTH CARE

WORKERS TOWARDS NIPAH VIRUS IN SOUTH

INDIA

Lauren Grace Himes1, Dr. Veena Shetty2,

Prathiksha RK3, Dr. Avinash Shetty1 1Wake Forest School of Medicine, Winston-Salem,

NC, United States, 2KS Hegde Medical Academy,

Mangalore, India, 3Mangalore University,

Mangalagangothri, India

LB-5155

The use of Critically Important Antimicrobials

in Thai pig production: survey of 84 pig farms

and 31 feed mills

Angkana Lekagul1, Viroj Tangcharoensathien2,

Anne Mills1, Jonathan Rushton3, Shunmay Yeung1 1London School of Hygiene and Tropical Medicine,

London, United Kingdom, 2International Health Policy

Programme, Ministry of Public Health, Nonthaburi,

Thailand, 3Institute of Infection and Global Health,

University of Liverpool, Liverpool, United Kingdom

LB-5156

Serologic evidence of exposure to known and

unknown henipaviruses in Cambodia

Spencer L. Sterling1, Phireak Hip2, Piseth Ly2, Pidor

Ouch2, Menghou Mao2, Dolyce H. Low3, Linaying

Yan1, Christopher C. Broder1, Ian H. Mendenhall3,

Jeffrey C. Hertz4, Eric D. Laing1 1Uniformed Services University, Bethesda, MD,

United States, 2Naval Medical Research Unit TWO,

Phnom Penh, Cambodia, 3Duke-NUS Medical School,

Singapore, Singapore, 4Naval Medical Research Unit

TWO, Singapore, Singapore

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30

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5157

Zika: Phase 1 Clinical Development of a Novel

Inactivated, Vero Cell derived Zika Virus

Vaccine

Andreas Pilz, Michaela Obersriebnig, Romana

Hochreiter, Susanne Eder-Lingelbach, Katrin

Dubischar

Valneva Austria GmbH, Vienna, Austria

LB-5158

Characterisation of naturally acquired human

antibody responses to Rift Valley fever virus

Daniel Wright1, Elizabeth Allen2, Iona Taylor1,

Madeleine Clark3, John Gitonga4, Henry Karanja5,

Sumi Biswas1, Jennifer Marshall1, Vish Nene6,

Bernard Bett6, Bryan Charleston3, Veronica Carr3,

Thomas A. Bowden2, George Warimwe4 1Jenner Institute, University of Oxford, Oxford,

United Kingdom, 2Wellcome Centre for Human

Genetics, Division of Structural Biology, University of

Oxford, Oxford, United Kingdom, 3The Pirbright

Institute, Pirbright, United Kingdom, 4KEMRI-

Wellcome Trust Research Programme, Kilifi,

Kenya, 5KEMRI-Wellcome Trust Research

Programme, Kenya, Kilifi, Kenya, 6International

Livestock Research Institute, Nairobi, Kenya

LB-5159

Integrated Nucleic Acid Testing Device for

Dengue Dignosis in Low-Resource Settings

Angelika Niemz1, Rama Sakamuri1, Hsiang Wei Lu1,

Abrar Al Maghribi1, Abrar Al-Adhmi1, Elizabeth

Celaya1, Hua Wei Chen2, Tania Maldonado2, Cheng-

Rei Lee2, Shuenn-Jue Wu2 1Keck Graduate Institute, Claremont, CA, United

States, 2Naval Medical Research Center, Silver

Springs, MD, United States

LB-5160

Post-chikungunya stiffness associated with

impaired mobility, discomfort and overall

disability

Hugh Robert Watson1, Sarah R. Tritsch2, Liliana

Encinales3, Andres Cadena4, Carlos Cure5, Alexandra

Porras Ramirez6, Alejandro Rico Mendoza6, Aileen Y.

Chang2 1Evotec ID (Lyon), Marcy l'Etoile, France, 2George

Washington School of Medicine and Health Sciences,

Washington, DC, United States, 3Allied Research

Society LLC, Barranquilla, Colombia, 4Clinica de La

Costa Ltda., Barranquilla, Colombia, 5Biomelab,

Barranquilla, Colombia, 6Universidad El Bosque,

Bogota, Colombia

LB-5161

Cross-neutralization of Chikungunya virus-

specific neutralizing antibodies to Mayaro virus

Elena Anelle Betancourt

Emergent BioSolutions, San Diego, CA, United States

LB-5162

Enhanced sequencing of Powassan virus

lineage II (Deer Tick virus) from ticks and

humans sheds light on its recent emergence

Erica Normandin1, Rebecca McMinn2, Rebecca

Robich3, Heidi Goethert4, Isaac Solomon5,

Christopher Tomkins-Tinch1, Siavash Zamirpour6,

Jacob Lemieux1, Daniel Park1, Robert Smith3, Sam

Telford III4, Gregory Ebel2, Pardis Sabeti1, Anne

Piantadosi7 1Broad Institute, Cambridge, MA, United

States, 2Colorado State University, Fort Collins, CO,

United States, 3Maine Medical Center, Scarborough,

ME, United States, 4Cummings School of Veterinary

Medicine at Tufts University, North Grafton, MA,

United States, 5Brigham and Women's Hospital,

Boston, MA, United States, 6Harvard College,

Cambridge, MA, United States, 7Emory University

School of Medicine, Atlanta, GA, United States

LB-5163

Combining anti IgM and IgG immunoassays for

comprehensive Chikungunya virus diagnostic

testing

Emelissa J. Mendoza

Public Health Agency of Canada, Winnipeg, MB,

Canada

LB-5164

Crimean-Congo Hemorrhagic Fever Virus in

Africa, an Underestimated Threat

Ahmet Irfan Temur1, Jens H. Kuhn2, David B. Pecor3,

Dmitry A. Apanaskevich4, Maryam keshtkar

Jahromi5 1Bezmialem Vakif University School of Medicine,

Istanbul, Turkey, 2Integrated Research Facility at

Fort Detrick, National Institute of Allergy and

Infectious Diseases, National Institutes of Health,

Frederick, MD, United States, 3Walter Reed

Biosystematics Unit, Smithsonian Institution Museum

Support Center, Suitland, MD, United

States, 4Department of Biology, Georgia Southern

University, Statesboro, GA, United States, 5Division

of Infectious Diseases, Johns Hopkins University,

Baltimore, MD, United States

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31

Poster Session A

Late Breakers in Clinical and Applied Sciences

Thursday, November 21, Noon - 1:45 p.m.

LB-5165

Characterization of a live-attenuated DENV-2-

based chimeric vaccine against Zika virus

Whitney Baldwin1, Holli Giebler1, Janae Stovall2,

Ginger Young3, Kelly Bohning3, Hansi Dean3, Jill

Livengood1, Claire Huang2 1Takeda Vaccines; CDC/NCEZID/DVBD/ADB, Fort

Collins, CO, United States, 2CDC/NCEZID/DVBD/ADB,

Fort Collins, CO, United States, 3Takeda Vaccines,

Cambridge, MA, United States

LB-5166

Risk estimation for male-to-female sexual

transmission of Zika virus—United States,

2016-2017

Chelsea G. Major1, Gabriela Paz-Bailey1, Susan L.

Hills2, Michael A. Johansson1 1Centers for Disease Control and Prevention, San

Juan, PR, United States, 2Centers for Disease Control

and Prevention, Fort Collins, CO, United States

LB-5167

Development and in vitro characterization of a

stable full-length ZIKV infectious clone carrying

heterologous genes

Evgeniya Volkova1, Konstantin Tsetsarkin2, Emilia

Sippert1, Felipe Assis1, Alexander Pletnev2, Maria

Rios1 1US FDA, Silver Spring, MD, United States, 2NIH,

Bethesda, MD, United States

LB-5168

CYD-TDV Vaccine efficacy after 1 and 2 doses

among seropositive subjects in dengue

endemic areas

Gustavo Dayan1, Edith Langevin2, Remi Forrat3,

Betzana Zambrano4, Fernando Noriega1, Carina

Frago5, Alain Bouckenooghe5, Stephen Savarino1,

Carlos DiazGranados1 1Sanofi Pasteur, Swiftwater, PA, United

States, 2Sanofi Pasteur, Lyon, France, 3Sanofi

Pasteur, Lyon, French Guiana, 4Sanofi Pasteur,

Montevideo, Uruguay, 5Sanofi Pasteur, Singapore,

Singapore

LB-5169

Chimpanzee adenovirus-vectored vaccines are

immunogenic and protective in a preclinical

model of Lassa fever

Jyothi Purushotham1, Robert Fischer2, Neeltje van

Doremalen2, Sarah Sebastian1, Kimberly Meade-

White3, Kathleen Cordova3, Jeremiah Matson2,

Friederike Feldmann3, Elaine Haddock2, Rachel

LaCasse3, Greg Saturday3, Sandra Belij-

Rammerstorfer1, Hannah Sharpe1, Ciaran Gilbride1,

Teresa Lambe1, Sarah Gilbert1, Vincent Munster2 1The Jenner Institute, University of Oxford, Oxford,

United Kingdom, 2Laboratory of Virology, Division of

Intramural Research, National Institute of Allergy

and Infectious Diseases, National Institutes of

Health, Rocky Mountain Laboratories, Hamilton, MT,

United States, 3Rocky Mountain Veterinary Branch,

Division of Intramural Research, National Institute of

Allergy and Infectious Diseases, National Institutes

of Health, Hamilton, MT, United States

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32

Poster Session 77

Poster Session B

Late-Breakers in Basic Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Friday, November 22, Noon - 1:45 p.m.

Arthropods/Entomology ........................................................#LB-5177 through LB-5190

Malaria ...............................................................................#LB-5191 through LB-5221

Protozoa .............................................................................#LB-5222 through LB-5229

Trematodes .........................................................................#LB-5230 through LB-5235

Viruses ...............................................................................#LB-5236 through LB-5245

LB-5177

A tropical cornucopia: Identifying putative

mosquito vectors in Rio Claro, Trinidad

Inshan Ali1, Raymond Martinez2, Christine

Carrington2 1General Hospital Port of Spain, Port of Spain,

Trinidad and Tobago, 2Department of Preclinical

Sciences, Faculty of Medical Sciences, The University

of the West Indies, St. Augustine, Trinidad and

Tobago

LB-5178

Vitellogenesis & the microbiome are regulated

by the ecdysone receptor

in Anopheles arabiensis

Elodie Ekoka, Luisa Nardini, Ayesha Aswat, Yael

Dahan-Moss, Lizette Koekemoer

University of the Witwatersrand, Johannesburg,

South Africa

LB-5179

Integrating genetic and environmental data to

create connectivity and habitat maps for tsetse

flies (Glossina pallidipes) in Kenya

Anusha Bishop, Norah Saarman, Evlyn Pless,

Giuseppe Amatulli, Adalgisa Caccone

Yale University, New Haven, CT, United States

LB-5180

Phenotypic response of Wolbachia pipientis in

an axenic culture media

Alyssa Krafsur, Corey L. Brelsfoard

Texas Tech University, Lubbock, TX, United States

LB-5181

High insecticide resistance in Aedes

albopictus in Hainan Island China, a tropical

area with high-risk epidemic of dengue fever

YIJI LI, Guiyun Yan

University of California, Irvine, IRVINE, CA, United

States

LB-5182

Insecticide resistance status and mechanism

in Anopheles gambiae populations in Senegal

Abdoulaye Kane DIA1, El Hadji Amadou NIANG1,

Badara SAMB1, Seynabou Mocote DIEDHIOU1,

Manthia DIALLO1, Moussa DIALLO1, Abdoulaye

DIOP2, Ousmane FAYE1, Lassana KONATE1 1Cheikh Anta Diop University, Dakar,

Senegal, 2PMI/VectorLink, Dakar, Senegal

LB-5183

Comparative analysis of

diverse Wolbachia strains across the life

history of Aedes aegypti

Heather A. Flores, Johanna M. Duyvestyn, Jaana

Wenham, Scott L. O'Neill, Cameron P. Simmons

Monash University, Clayton, Australia

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33

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5184

Evaluation of the insecticidal effect of Solanum

mammosum L. (Solanaceae) aqueous extract

and extract-covered nanoparticles

against Aedes aegypti L. (Diptera: Culicidae)

Fernanda Pilaquinga1, Bianca Morejón1, Danny

Ganchala1, Jeroni Morey2, Neus Piña2, Alexis

Debut3, Marco V. Neira1 1Pontificia Universidad Católica del Ecuador, Quito,

Ecuador, 2University of the Balearic Islands, Palma

de Mallorca, Spain, 3Universidad de las Fuerzas

Armadas ESPE, Quito, Ecuador

LB-5185

Engineering Zika virus resistance in

transgenic Aedes aegypti

Adeline Williams1, William Reid2, Irma Sanchez-

Vargas1, Alexander Franz2, William Black IV1,

Malcolm Fraser3, Kenneth Olson1 1Colorado State University, Fort Collins, CO, United

States, 2University of Missouri, Columbia, MO, United

States, 3The University of Notre Dame, South Bend,

IN, United States

LB-5186

Some like it hot - land cover influences

microclimate and mosquito abundance in

south-central United States

Andrea Hess, Michael C. Wimberly

University of Oklahoma, Norman, OK, United States

LB-5187

Mosquito and arbovirus community

composition in the northeast United States

Joseph McMillan, Philip Armstrong, Theodore

Andreadis

The Connecticut Agricultural Experiment Station,

New Haven, CT, United States

LB-5188

Novel and population-specific viral integrations

in the genomes of wild-

collected Aedes arboviral vectors

Umberto Palatini, Elisa Pischedda, Michele

Marconcini, Annamaria Mattia, Cristina Crava,

Mariangela Bonizzoni

University of Pavia, Pavia, Italy

LB-5189

Immunological properties

of mosquito symbionts engineered to be

covered by a protein of Wolbachia

SARA EPIS1, ILARIA VAROTTO BOCCAZZI1, ELENA

CROTTI1, LAURA GIOVATI2, CLAUDIA DAMIANI3,

PAOLO GABRIELI1, MAURO MANDRIOLI4, RICCARDO

NODARI1, IRENE ARNOLDI1, GUIDO FAVIA3, DANIELE

DAFFONCHIO5, CLAUDIO BANDI1 1Università degli Studi di Milano, Milano,

Italy, 2Università degli Studi di PARMA, PARMA,

Italy, 3Università degli Studi di CAMERINO,

CAMERINO, Italy, 4Università degli Studi di Modena

Reggio Emilia, Modena, Italy, 5King Abdullah

University of Science and Technology, Thuwal, Saudi

Arabia

LB-5190

Ochlerotatus scapularis (Rondani, 1848), the

lynchpin to the taxonomic revision of the

Scapularis Group (Diptera: Culicidae)

Vinicios Ferreira-de-Freitas, Lyric Bartholomay

University of Wisconsin-Madison, Madison, WI,

United States

LB-5191

Peptides in Semi-conserved Domains of

Plasmodium falciparum Erythrocyte Membrane

Protein 1 Variants Associated with the

Development of Protective Immunity Against

Malaria Infection in Malian Children

Brittany Araj1, Patricia Gonzales Hurtado1, Robert

Morrison1, Bruce Swihart1, Andrew Teo1, Alassane

Dicko2, Patrick Duffy1, Michal Fried1 1National Institutes of Health, Bethesda, MD, United

States, 2Malaria Research and Training Center,

Faculty of Medicine, Pharmacy and Dentistry,

University of Sciences Techniques and Technologies

of Bamako, Bamako, Mali

LB-5192

The global var gene repertoire of Plasmodium

falciparum

Thomas D. Otto1, PF3K Consortium2, Dominic

Kwiatkowski2, Matt Berriman2, Chris Newbold3 1University of Glasgow, Glasgow, United

Kingdom, 2Wellcome Sanger Insitute, Cambridge,

United Kingdom, 3University of Oxford, Oxford,

United Kingdom

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34

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5193

Towards the optimization of Anopheles

gambiaedoublesex gene-silencing though oral

RNAi for female elimination in mass rearing for

sterile male release

Mabel L. Taracena1, Catherine M. Hunt1, Mark Q.

Benedict1, Pamela M. Pennington2, Ellen M. Dotson1 1Centers for Disease Control, Atlanta, GA, United

States, 2Universidad del Valle de Guatemala,

Guatemala City, Guatemala

LB-5194

Immunologic profiles defining clinical states in

malaria

Maureen Ty1, Lauren de la Parte1, Rek John2,

Richard Kajubi2, Moses Kamya3, Holden Maecker1,

Bryan Greenhouse4, Margaret Feeney4, Grant

Dorsey4, Bali Pulendran1, Prasanna Jagannathan1 1Stanford University, Stanford, CA, United

States, 2Infectious Diseases Research Collaboration,

Kampala, Uganda, 3Makerere University School of

Medicine, Kampala, Uganda, 4University of California,

San Francisco, CA, United States

LB-5195

Malaria Knowledge and Experiences with

Community Health Workers among Recently

Pregnancy Women in Malawi

Ashley L. Malpass

USAID/President's Malaria Initiative, Malawi,

Lilongwe, Malawi

LB-5196

PfMSA180 is a novel Plasmodium

falciparum vaccine candidate that interacts

with CD47 on erythrocytes

Eizo Takashima1, Hikaru Nagaoka1, Chisa Sasaoka1,

Takaaki Yuguchi1, Bernard N. Kanoi1, Daisuke Ito2,

Masayuki Morita1, Rachanee Udomsangpetch3,

Jetsumon Sattabongkot4, Tomoko Ishino5, Takafumi

Tsuboi1 1Division of Malaria Research, Proteo-Science Center,

Ehime University, Matsuyama, Japan, 2Division of

Medical Zoology, Department of Microbiology and

Immunology, Faculty of Medicine, Tottori University,

Yonago, Japan, 3Center for Research and Innovation,

Faculty of Medical Technology, Mahidol University,

Salaya, Thailand, 4Mahidol Vivax Research Unit,

Faculty of Tropical Medicine, Mahidol University,

Bangkok, Thailand, 5Division of Molecular

Parasitology, Proteo-Science Center, Ehime

University, Toon, Japan

LB-5197

ETHICAL DIMENSIONS OF RESEARCH STUDIES

EVALUATING NEW MOSQUITO CONTROL TOOLS

IN SOUTH-EASTERN TANZANIA

Rukiyah Mohammed Njalambaha, Marceline F

Finda, Halfan S Ngowo, Fredros O Okumu

Ifakara Health Institute, Morogoro, Tanzania, United

Republic of

LB-5198

Molecular characterization of the Plasmodium

vivax hsp70 promoter sequence using

heterologous transfection

Roberto R. Moraes Barros1, Thafne P. Astro1,

Matheus R. Carvalho1, Tais B. Vieira1, Tyler J.

Gibson2, Thomas E. Wellems2, Juliana M. Sa2 1UNIFESP, São Paulo, Brazil, 2LMVR-NIAID-NIH,

Bethesda, MD, United States

LB-5199

Kelch 13 mutations in Plasmodium berghei:

an in vivo model to understanding artemisinin

resistance

Nelson Victor Simwela1, Dana Aghabi1, David

Fidock2, Andy Waters1 1University of Glasgow, Glasgow, United

Kingdom, 2Columbia University Medical Center, New

York, NY, United States

LB-5200

Strengthening the quality of malaria

microscopy diagnosis in Senegal between 2016

and 2018

Ibrahima Diallo1, Moustapha CISSE1, Medoune

NDIOP1, Alioune Badara GUEYE1, Ngouda TALL1,

Fatou BA1, Doudou SENE1, Babacar FAYE2, Daouda

NDIAYE2 1Senegal National Malaria Control Program, Dakar

Fann, Senegal, 2Senegal Laboratoire de Parasitologie

UCAD, Dakar Fann, Senegal

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35

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5201

Molecular monitoring of Plasmodium

falciparum resistance in malaria sentinel sites

in Cote d'Ivoire

William Yavo1, Abibatou Konate1, Paterne A.

Gnagne2, Valerie A. Bedia1, Mireille A. Amiah2,

Pulcherie M-C Kiki-Barro3, Herve E.I Menan4 1Department of Parasitology and Mycology-University

Felix Houphouet-Boigny, Malaria Research and

Control Center-National Institute of Public Health,

Abidjan, Côte D'Ivoire, 2Malaria Research and Control

Center-National Institute of Public Health, Abidjan,

Côte D'Ivoire, 3Department of Parasitology and

Mycology-University Felix Houphouet-Boigny,

Abidjan, Côte D'Ivoire, 4Department of Parasitology

and Mycology-University Felix Houphouet-Boigny,

Diagnosis and Research Centre on AIDS and the

others infectious diseases, Abidjan, Côte D'Ivoire

LB-5202

Assessing a common laboratory model

of Plasmodium falciparum placental malaria

pathogenesis against clinical isolates

Bethany Jenkins, Robert Morrison, Patricia

Gonzales Hurtado, Pragyan Acharya, Patrick Duffy,

Michal Fried

National Institutes of Health, Bethesda, MD, United

States

LB-5203

Production of novel pre-erythrocytic vaccine

candidates in a E. coli

Matthew V. Cowles, Jonathan P. Renn, Holly M.

Torano, Shaji Daniel, Patrick E. Duffy

NIH, Bethesda, MD, United States

LB-5204

Community-based survey of Plasmodium

falciparum Pfhrp2 and Pfhrp3 gene deletions in

different regions of Mainland Tanzania

Catherine Bakari1, Celine I. Mandara2, Mercy G.

Chiduo2, Susan F. Rumisha3, Frank Chacky4, Fabrizio

Molteni4, Renata Mandike5, Sigsbert Mkude5, Ritha

Njau6, Ally Mohamed4, Caleb K. Kibet1, Steven G.

Nyanjom1, Deus S. Ishengoma2 1Jomo Kenyatta University of Agriculture and

Technology, Nairobi, Kenya, 2National Institute of

Medical Research, Tanga, Tanzania, United Republic

of, 3National Institute for Medical Research,

Headquarters, Dar es Salaam, Dar es Salaam,

Tanzania, United Republic of, 4National Malaria

Control Program (NMCP), Dodoma, Tanzania, United

Republic of, 5Swiss Tropical and Public Health

Institute, Dar es Salaam, Tanzania, United Republic

of, 6World Health Organisation Country Office, Dar es

Salaam, Tanzania, United Republic of

LB-5205

Developing a native protein

immunoprecipitation method to identify targets

of immunity in p. falciparum infected isolates

Patricia A. Gonzales Hurtado, Michal Fried

National Institute of Allergy and Infectious Diseases,

Bethesda, MD, United States

LB-5206

Molecular approaches to species and biological

form identification of Anopheles stephensi

Sae Hee E. Choi1, Joseph Spear1, Meshesha

Balkew2, Peter Mumba2, Dereje Dengela3, Gedeon

Yohannes2, Dejene Getachew4, Solomon Yared5,

Sheleme Chibsa6, Matthew Murphy7, Kristen George8,

Cecelia Flately3, Karen Lopez9, Daniel Janies9, Seth

R. Irish10, Tamar E. Carter1 1Baylor University, Waco, TX, United States, 2Abt

Associates, PMI VectorLink Ethiopia Project, Addis

Ababa, Ethiopia, 3Abt Associates, PMI VectorLink

Project, Rockville, MD, United States, 4Dire Dawa

University, Dire Dawa, Ethiopia, 5Department of

Biology, Jigjiga University, Jigjiga, Ethiopia, 6U.S

President's Malaria Initiative (PMI), United States

Agency for International Development (USAID),

Addis Ababa, Ethiopia, 7U.S. President's Malaria

Initiative and Malaria Branch, Division of Parasitic

Diseases and Malaria, Centers for Global Health,

Centers of Disease Control and Prevention, Atlanta,

GA, United States, 8U.S. President's Malaria Initiative

and USAID, Bureau for Global Health, Office of

Infectious Disease, Malaria Division, Arlington, VA,

United States, 9University of North Carolina at

Charlotte, Charlotte, NC, United States, 10U.S.

President's Malaria Initiative and Entomology Branch,

Centers for Disease Control and Prevention, Atlanta,

GA, United States

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36

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5207

Genetic diversity of Anopheles stephensi in

eastern Ethiopia

Tamar E. Carter1, Solomon Yared2, Sae Hee Choi1,

Joseph Spear1, Peter Mumba3, Dereje Dengela4,

Dejene Getachew5, Sheleme Chibsa6, Matthew

Murphy7, Gunawardena Dissanayake6, Kristen

George8, Cecilia Flately4, Karen Lopez9, Daniel

Janies9, Seth Irish10, Meshesha Balkew3 1Baylor University, Waco, TX, United States, 2Jigjiga

University, Jigjiga, Ethiopia, 3Abt Associates, PMI

VectorLink Ethiopia Project, Addis Ababa,

Ethiopia, 4Abt Associates, PMI VectorLink Project,

Rockville, MD, United States, 5Dire Dawa University,

Dire Dawa, Ethiopia, 6U.S President’s Malaria

Initiative (PMI), United States Agency for

International Development (USAID), Addis Ababa,

Ethiopia, 7U.S. President's Malaria Initiative and

Malaria Branch, Division of Parasitic Diseases and

Malaria, Centers for Global Health, Centers of

Disease Control and Prevention, Atlanta, GA, United

States, 8US President’s Malaria Initiative and USAID,

Bureau for Global Health, Office of Infectious

Disease, Malaria Division, Arlington, VA, United

States, 9University of North Carolina at Charlotte,

Charlotte, NC, United States, 10US President’s Malaria

Initiative and Entomology Branch, Centers for

Disease Control and Prevention, Atlanta, GA, United

States

LB-5208

Dormancy and Recovery of the Arrest

in Plasmodium falciparum Isolates Against

Artemisinin-based Combination Therapy

Rosa Del Carmen Miluska Vargas Rodriguez1,

Andrés Jimenez Galisteo Jr.2, Maria de Jesus Costa

do Nascimento3, Silvia Maria Fátima Di Santi4 1National University of the Peruvian Amazon, Iquitos,

Peru, 2Instituto de Medicina Tropical de São

Paulo/Universidade de São Paulo, São Paulo,

Brazil, 3Núcleo de Estudos em

Malária/Superintendência de Controle de Endemias,

São Paulo, Brazil, 4Faculdade de

Medicina/Universidade de São Paulo/Núcleo de

Estudos em Malária/Superintendência de Controle de

Endemias, São Paulo, Brazil

LB-5209

A spatio-temporal entomological study of

malaria vectors in NE Uganda, the interplay of

two species and their measured population

declines from vector control

Richard Elliott1, Wycliff Odude2, Maxwell Kilama2,

Thomas Eganyu2, Ronald Mulebeke3, Kathryn

Colborn4, Adoke Yeka3, Dorothy Echodu2 1Boise State University, Boise, ID, United

States, 2Pilgrim Africa, Kampala, Uganda, 3Makerere

University, Kampala, Uganda, 4Colorado School of

Public Health, University of Colorado, Denver,

Denver, CO, United States

LB-5210

Immune response to Plasmodium falciparum

and Plasmodium vivax parasites in

asymptomatic school children in the Southern

of Senegal

Aminata C. LO1, Katie Patterson2, Tate Oulton2,

Aminata Lam1, Ndeye Aida Gaye1, Babacar Faye1,

Jean Louis Ndiaye1, Oumar Gaye1, Christopher

Drakeley2 1University Cheikh Anta DIOP of Dakar / Senegal,

Dakar, Senegal, 2London School of Hygiene and

Tropical Medicine, London, United Kingdom

LB-5211

Expression of pyrethroid metabolizing P450

enzymes characterizes highly resistant

Anopheles vector species targeted by

successful deployment of PBO treated bednets

in Tanzania

Johnson Jason Nderingo Matowo

Kilimanjaro Christian Medical University College,

Moshi, Tanzania, United Republic of

LB-5212

Plasmodium falciparum self regulates parasite

population in vitro through extracellular

vesicles

Ricardo Correa1, Lorena Coronado1, Zuleima

Caballero1, Paula Faral-Tello2, Carlos Robello2,

Carmeza Spadafora1 1INDICASAT AIP, Panama City, Panama, 2Institut

Pasteur, Montevideo, Uruguay

LB-5213

Characterization and imaging analysis of a

blood-stage vaccine candidate, PfLSA3, during

erythrocyte invasion of malaria merozoites

Masayuki Morita1, Charlie Jennison2, Tomoko

Ishino3, Matthew T. O'Neill4, Justin A. Boddey4, Eizo

Takashima1, Takafumi Tsuboi1 1Division of Malaria Research, Proteo-Science Center,

Ehime University, Matsuyama, Japan, 2Center for

Global Infectious Disease Research, Seattle

Children’s Research Institute, Seattle, WA, United

States, 3Division of Molecular Parasitology, Proteo-

Science Center, Ehime University, Toon, Japan, 4The

Walter and Eliza Hall Institute of Medical Research,

Melbourne, Australia

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37

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5214

The N-terminal region of Plasmodium

falciparum MSP10 is important for

PfGAMA/MSP10 interaction and is a target of

protective antibodies

Hikaru Nagaoka1, Bernard N. Kanoi1, Kana Jinoka1,

Masayuki Morita1, Thangavelu U Arumugam1,

Nirianne M. Q. Palacpac2, Thomas G. Egwang3,

Toshihiro Horii4, Takafumi Tsuboi1, Eizo Takashima1 1Ehime University, Matsuyama, Ehime,

Japan, 2Osake University, Suita, Osaka, Japan, 3Med

Biotech Laboratories, Port Bell Road Luzira, Kampala,

Uganda, 4Osaka University, Suita, Osaka, Japan

LB-5215

Plasmodium falciparum in vivo clearance time

after artesunate treatment in Mali

Aminatou Kone, Antoine Dara, Nouhoum Diallo,

Aboubecrine Haidara, Cheick Papa Sangare, Issaka

Sagara, Ogobara K. Doumbo, Abdoulaye Djimde

USTTB, Bamako, Mali

LB-5216

MALARIA vaccine SITE characterization & THE

PREVALENCE & species distribution of malaria

PLASMODIUM

Diarra AMIDOU1, NEBIE ISSA1, TIONO ALFRED B.1,

YARO JEAN B.1, OUEDRAOGO ALPHONSE1, KONATE

AMADOU T.1, SOULAMA ISSIAKA1, SIRIMA

SODIOMON B.1, SIRIMA SODIOMON B.2 1CNRFP, Ouagadougou, Burkina Faso, 2CNRFP, GRAS,

Ouagadougou, Burkina Faso

LB-5217

Identifying targets of functional antibody

responses against Plasmodium vivax malaria

HERBERT OPI1, Rhea Longley2, Linda Reiling1,

Damien Drew1, Gaoqian Feng1, Matthias Harbers3,

Benson Kiniboro4, Enmoore Lin4, Danielle Stanisic5,

Takafumi Tsuboi6, Leanne Robinson1, Ivo Mueller7,

James Beeson1 1THE BURNET INSTITUTE FOR MEDICAL RESEARCH

AND PUBLIC HEALTH, MELBOURNE, Australia, 2The

Walter and Eliza Hall Institute of Medical Research,

MELBOURNE, Australia, 3CellFree Sciences Company

Limited, Yokohama, Japan, 4Papua New Guinea

Institute of Medical Research, Madang, Papua New

Guinea, 5Institute for Glycomics, Griffith University,

Southport, Australia, 6Division of Malaria Research,

Proteo-Science Center, Ehime University,

Matsuyama, Japan, 7The Walter and Eliza Hall

Institute for Medical Research, MELBOURNE,

Australia

LB-5218

Realtime molecular and genomic investigation

of an outbreak of atypical malaria cases in the

pre-elimination setting of Kanel, northern

Senegal

Aida S. Badiane1, Awa B. Deme1, Mouhamad Sy1,

Tolla Ndiaye1, Amy Gaye1, Yaye Die Ndiaye1, Fatou

Ba Fall2, Doudou Sene2, Medoune Ndiop2, Alioune

Badara Gueye2, Ibrahima Diallo2, Sarah K. Volkman3,

Bronwyn MacInnis4, Katherine Siddle4, Daouda

Ndiaye1 1University Cheikh Anta Diop, Dakar,

Senegal, 2Senegal National Malaria Control Program,

Dakar, Senegal, Dakar, Senegal, 3Harvard T.H. Chan

School of Public Health, Boston, MA, United

States, 4Broad Institute, Cambridge, MA, United

States

LB-5219

Sequence analysis of Plasmodium

falciparum histidine-rich protein 2 and 3 genes

from returning travelers to Africa

Rachel Lau1, Ayomide Olubanwo2, Filip Ralevski1,

Aisha Khatib1, Andrea K. Boggild2 1Public Health Ontario Laboratories, Toronto, ON,

Canada, 2Tropical Disease Unit, Toronto General

Hospital, Toronto, ON, Canada

LB-5220

Molecular probe-based multiplex qPCR

identifies bloodmeal hosts and

detects Plasmodium infection

in Anopheles mosquitoes from Papua New

Guinea

Georgia H. Artzberger, John B. Keven, Mary L.

Gillies, Rex B. Mbewe, Edward D. Walker

Michigan State University, East Lansing, MI, United

States

LB-5221

Immunogenicity and functional activity in

BALB/c mice of the Plasmodium

vivax Pvs48/45 recombinant protein

formulated in different adjuvants for human

use.

Eduardo A. Solano1, Nora Cespedes2, Daniela

Gutierrez1, Michelle Pardo2, Juan S. Ramirez1,

Socrates Herrera1, Myriam Arevalo-Herrera2 1Caucaseco Research Center, Cali, Colombia, 2Malaria

Vaccine and Drug Development Center, Cali,

Colombia

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38

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5222

Occurrence of a Novel genotype

of Enterocytozoon bieneusi circulating in

Mozambican children

Augusto E. Messa Jr.1, Alejandro Dashti2, Filomena

A. Manjate1, Percina J. Chirinda1, Marcelino Garrine1,

Delfino Vubil1, Sozinho Acacio1, Monica Santin3,

Tacilta Nhampossa1, Pedro Alonso4, Inácio

Mandomando1, David Carmena2 1Manhiça Health Research Centre, Manhiça,

Mozambique, 2Laboratorio de Referencia e

Investigación en Parasitología, Centro Nacional de

Microbiología – Instituto de Salud Carlos III,

Majadahonda - Madrid, Spain, 3Environmental

Microbial and Food Safety Laboratory, Agricultural

Research Service, United States Department of

Agriculture, Beltsville, MD, United States, 4ISGlobal,

Hospital Clínic – Universitat de Barcelona, Barcelona,

Spain

LB-5223

The microsporidium Encephalitozoon

cuniculi genotype III withstood the treatment

with hundredfold recommended dose of

Albendazole in both immunodeficient and

immunocompetent mice

Bohumil Sak

Biology Centre, CAS, Ceske Budejovice, Czech

Republic

LB-5224

Investigation of a Series of 1,4-diaryl-pyrazolo-

pyridinones as Anti-Leishmanial Agents

Hannah N. Corman, Douglas A. Shoue, Bruce J.

Melancon, Mary Ann McDowell

University of Notre Dame, Notre Dame, IN, United

States

LB-5225

The novel thioredoxin-related protein 1 (TrxL-

1) of the malaria parasite Plasmodium exhibits

redox activity

Stefan Kanzok, Kaitlyn Kiernan, Emily Zurales,

Robin David

Loyola University Chicago, Chicago, IL, United States

LB-5226

Plasmodium TLAP-2 is a microtubule-

associated protein with microtubule

stabilization properties

Grifin Berge, Stefan Kanzok

Loyola University Chicago, Chicago, IL, United States

LB-5227

Development of a novel small RNA-based

therapy to cure Cryptosporidium infection

Alejandro Castellanos-Gonzalez, Aygul Sadiqova,

Arthur Clinton White Jr

Infectious Diseases Division, University of Texas

Medical Branch, Galveston Tx, TX, United States

LB-5228

The Protein-Protein Interaction Landscape of

the Apicomplexan Parasite Toxoplasma gondii

Lakshmipuram S. Swapna1, Grant C. Stevens1,

Aline Sardinha-Silva2, Zhongming Hu3, Verena

Brand1, Jon Boyle4, Michael Grigg2, Andrew Emili5,

John Parkinson1 1Hospital for Sick Children, Toronto, ON,

Canada, 2National Institute of Health, Bethesda, MD,

United States, 3University of Toronto, Toronto, ON,

Canada, 4University of Pittsburgh, Pittsburgh, PA,

United States, 5Boston University, Boston, MA,

United States

LB-5229

Analysis of Cryptosporidium parvumin

Bangladesh

Carol A. Gilchrist1, Tuhinur Arju2, Maureen Carey1,

Mamun Kabir2, Uma Nayak1, Kevin Steiner1, ASG

Faruque2, Rashidul Haque2, Masud Alum2, William A.

Petri1 1University of Virginia HSC, Charlottesville, VA,

United States, 2icddr,b, Dhaka, Bangladesh

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39

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5230

Low-input approaches to generate high-quality

reference genomes for parasitic flatworms

Duncan Berger1, Sarah Buddenborg1, Muriel

Rabone2, Aiden Emery2, Fiona Allan2, Michelle

Smith1, Karen Oliver1, Nancy Holroyd1, Craig Corton1,

Christine Lambert3, Primo Baybayan3, Sarah Kingan3,

Jonas Korlach3, James A. Cotton1, Shona Wilson4,

Joanne P. Webster5, Matthew Berriman1 1Wellcome Sanger Institute, Cambridge, United

Kingdom, 2Department of Life Sciences, Natural

History Museum, London, United Kingdom, 3Pacific

Biosciences, 1305 O’Brien Drive, Menlo Park, CA,

United States, 4Department of Pathology, University

of Cambridge, Cambridge, United

Kingdom, 5Department of Pathology and Pathogen

Biology, Centre for Emerging, Endemic and Exotic

Diseases, Royal Veterinary College, University of

London, London, United Kingdom

LB-5231

Plasticity of susceptibility of Biomphalaria

glabrata to infection with Schistosoma

mansoni: interplay betweenPiwi and nimbus

Michael Smith1, Swara Yadav2, Olayemi Akinyele2,

Nana Adjoa Pels2, Carolyn Cousin2, Freddie Dixon2,

Victoria Mann3, Clarence Lee1, Paul J. Brindley2,

Matty Knight2 1Howard University, N.W. Washington, DC, United

States, 2University of the District of Columbia, N.W.

Washington, DC, United States, 3George Washington

University, N.W. Washington, DC, United States

LB-5232

Differential expression of lncRNAs in molluscan

and mammalian stages of Schistosoma

mansoni

Hyung Chul Kim, Emmitt Jolly

Case Western Reserve University, Cleveland, OH,

United States

LB-5233

Analyses on the population genetics

of Fasciola flukes reveal the cross-infection

between domestic cattle and wild sika deer in

Hokkaido, Japan

Yuma Ohari1, Takao Irie2, Shin-ichiro Kawazu1,

Tadashi Itagaki3 1National Research Center for Protozoan Diseases,

Obihiro University of Agriculture and Veterinary

Medicine, Obihiro, Hokkaido, Japan, 2Medical Zoology

Group, Department of Infectious Diseases, Hokkaido

Institute of Public Health, Sapporo, Hokkaido,

Japan, 3Laboratory of Veterinary Parasitology,

Faculty of Agriculture, Iwate University, Morioka,

Iwate, Japan

LB-5234

Schistosometegumental ectoenzymes - the

roles of SmNPP5 and NACE in NAD catabolism

Catherine S. Nation, Akram A. Da'Darah, Patrick J.

Skelly

Molecular Helminthology Laboratory, Department of

Infectious Disease and Global Health, Cummings

School of Veterinary Medicine, Tufts University,

North Grafton, MA, United States

LB-5235

Exosome mediated cellular crosstalk in

response to liver fluke granulin promotes a

microenvironment conducive to

cholangiocarcinoma

Wanaporn Ittiprasert

The George Washington University, Washington, DC,

United States

LB-5236

Emergence of a novel chikungunya virus strain

out of the Mombasa, Kenya 2017 outbreak

Fredrick L. Eyase1, Solomon Langat1, Irina

Maljkovic Berry2, Francis Mulwa1, Albert Nyunja1,

James Mutisya1, Samuel Owaka1, Samson Limbaso3,

Victor Ofula1, Hellen Koka1, Edith Koskei1, Joel

Lutomiah3, Richard G. Jarman2, John Distelhorst1,

Rosemary C. Sang3 1US Army Medical Research Directorate-Africa,

Nairobi, Kenya, 2Walter Reed Army Institute of

Research, Silver Spring, MD, United States, 3Kenya

Medical Research Institute, Nairobi, Kenya

LB-5237

Vector competence of two

Argentinean Culex mosquito species for West

Nile virus (Flavivirus, Flaviviridae)

Octavio Giayetto1, Mauricio Beranek2, Nicolas

Nazar3, Adrian Diaz2 1Instituto de Virología "Dr. J. M. Vanella" - Facultad

de Ciencias Médicas - Universidad Nacional de

Cordoba, Córdoba, Argentina, 2Instituto de Virología

"Dr. J. M. Vanella" - Facultad de Ciencias Médicas,

Universidad Nacional de Cordoba, Córdoba,

Argentina, 3Instituto de Investigaciones Biológicas y

Tecnológicas (IIByT, CONICET, UNC). Córdoba,

Argentina, Córdoba, Argentina

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40

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5238

Antigenic characterization of a genetically

divergent sylvatic dengue virus type 2 isolated

from a traveller visiting Borneo

Ana G. Coello Escoto1, Leah Katzelnick1, Sonja

Best2, Nayeem Chowdhury1, Shelly J. Robertson2,

Joanna M. Swerczek2, Richard Herbert2, Wen-jun

Liu3, Steve Whitehead2, Derek Cummings1, John

Aaskov4 1University of Florida, Gainesville, FL, United

States, 2National Institute of Allergy and Infectious

Diseases, National Institutes of Health, Bethesda,

MD, United States, 3Australian Defense Force

Infectious Diseases Institute, Brisbane,

Australia, 4Queensland University of Technology,

Brisbane, Australia

LB-5239

Maternally transferred of neutralizing

antibodies against dengue and chikungunya

viruses in Thai infants

Taweewun Hunsawong1, Weerawan Hattasingh2,

Prapapun Ong-ajchaowlerd1, Rungarun

Suthangkornkul1, Butsaya Thaisomboonsuk1, Damon

W. Ellison3, Louis R. Macareo1, Anthony R. Jones1,

Stefan Fernandez1 1USAMC-AFRIMS, Bangkok, Thailand, 2Faculty of

Tropical Medicine, Mahidol University, Bangkok,

Thailand, 3Viral Diseases Branch, Walter Reed Army

Institute of Research, Silver spring, MD, United

States

LB-5240

Zika Virus infection and its effect on CREB3L1

Joaris Soto-Hernández, Pablo López, Yashira

García, Eileen Pabón-Cruz, Vanessa Rivera-Amill

Ponce Research Institute-Ponce Health Sciences

University, Ponce, PR, United States

LB-5241

An assessment of the impact of sample type

variation on single cell RNA sequencing data

quality: implications for infectious disease

research

Kaitlin Victor, Hayden Siegfried, Tao Li, Wiriya

Rutvisuttinunt, Damon W. Ellison, Richard G.

Jarman, Jeffrey R. Currier, Heather Friberg, Adam T.

Waickman

Walter Reed Army Institute of Research, Silver

Spring, MD, United States

LB-5242

Determination of antigen receptor specificity

derived from single cell RNA sequencing

analysis of circulating plasmablasts

Hayden Siegfried, Kaitlin Victor, Caitlin Kuklis,

Wiriya Rutvisuttinunt, Damon Ellison, Richard G.

Jarman, Jeffrey R. Currier, Heather Friberg, Gregory

D. Gromowski, Adam T. Waickman

Walter Reed Army Institute of Research, Silver

Spring, MD, United States

LB-5243

Examining efforts towards the eradication of

Vaccine Derived Polio Virus among children

under five years old in the Democratic Republic

of the Congo

Kamy K. Musene1, Sylvia Tangney2, Nicole A. Hoff2,

Megan Halbrook2, Camille T. Dzogang1, Merly Y.

Tambu3, D'André Spencer2, Cyrus S. Sinaï2, Patrick

K. Mukadi3, Sue Gerber4, Frank Salet5, Michel K.

Nyembwe6, Guillaume Ngoie7, Trevon Fuller2, Michel

N. Kabamba7, Jean Jacques T. Muyembe3, Emile W.

Okitolonda1, Anne W. Rimoin2 1Kinshasa school of Public Health, Kinshasa, Congo,

Democratic Republic of the, 2Ucla Fielding School of

Public Health, Los Angeles, CA, United

States, 3National Institute of Biomedical Research,

Kinshasa, Congo, Democratic Republic of the, 4Bill

and Melinda Gate Foundation, seattle, WA, United

States, 5McKing Consulting, seattle, WA, United

States, 6DRC Expanded Program of Immunization,

kinshasa, Congo, Democratic Republic of the, 7DRC

Expanded Program of Immunization, Kinshasa,

Congo, Democratic Republic of the

LB-5244

Exploring the Potential of Next-Generation

Sequencing in the detection of pathogens from

febrile cases

Clara N. Yeboah1, Selassie Kumordjie1, Bright

Agbodzi1, Mba-Tihsommah Mosore1, Ronald Bentil1,

Janice Tagoe1, Shirley Nimo-Painstil2, Naiki Attram2,

Edward Nyarko3, William Ampofo1, Catherine Pratt4,

Micheal Wiley4, Anne Fox2, David Wolfe2, Andrew

Letizia2 1Noguchi Memorial Institute for Medical Research,

University of Ghana, Legon, Accra, Ghana, 2US Naval

Medical Research Unit Three Ghana Detachment

(NAMRU-3 GD), Accra, Ghana, 337 Military Hospital,

Accra, Ghana, 4University of Nebraska Medical

Center, Omaha, NE, United States

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41

Poster Session B

Late-Breakers in Basic Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5245

Ribosome Display for the Generation and

Selection of a Panel of Pan-Filovirus Single-

Chain Antibodies as Diagnostics

Adinarayana Kunamneni1, Elizabeth C Clarke2,

Chunyan Ye2, Dawid Maciorowski1, Steven

Bradfute2, Ravi Durvasula1 1Loyola University Chicago, Maywood, IL, United

States, 2University of New Mexico, Albuquerque, NM,

United States

Page 43: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

42

Poster Session 77

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Friday, November 22, Noon - 1:45 p.m.

Bacteriology and Diarrhea .....................................................#LB-5246 through LB-5263

Global Health .......................................................................#LB-5264 through LB-5286

Kinetoplastida ......................................................................#LB-5287 through LB-5292

Malaria ...............................................................................#LB-5293 through LB-5330

Pneumonia, Respiratory Infections and Tuberculosis .................#LB-5331 through LB-5337

Trematodes .........................................................................#LB-5338 through LB-5339

Viruses ...............................................................................#LB-5340 through LB-5351

LB-5246

The change in organisms responsible for septic

arthritis in a high income country over a ten

year period

Robin Thomas Hilder

NHS, Preston, United Kingdom

LB-5247

Acquired syphilis by non sexual contact in

childhood

Guillermo Moscatelli, Samanta Moroni, Facundo

Garcia Bournissen, Nicolas Falk, Alejandra Destito,

Nicolas Gonzalez, Fernanda Lascano, Griselda

Ballering, Luciana Garcia, Jaime Altcheh

Parasitology service Ricardo Gutiérrez Children´s

Hospital, Hospital de Niños R. Gutiérrez, Buenos

Aires, Argentina

LB-5248

Does infection and antibody data add evidence

to the understanding of trachoma prevalence in

low endemic areas

Mabula Joseph Kasubi1, George Kabona2, Harran

Mkocha3, Mike French4, Upendo Mwingira5, Sarah

Gwyn6, Diana Martin7, Sheila West8, Jeremiah

Ngondi9 1Muhimbili National Hospital, Dar Es Salaam,

Tanzania, United Republic of, 2Iringa Regional

Referral Hospital, Iringa, Tanzania, United Republic

of, 3Kongwa Trachoma Project, Dodoma, Tanzania,

United Republic of, 4RTI International, Washington

DC, MD, United States, 5Ministry of Health, Dar Es

Salaam, Tanzania, United Republic of, 6Centre for

Disease Control and Prevention, Atlanta, GA, United

States, 7Centre for Disease Control and Prvention,

Atlanta, GA, United States, 8Johns Hopkins

University, Baltimore, MD, United States, 9RTI

International, Washington DC, MD, United States

LB-5249

Achieving coordinated national immunity and

cholera elimination in Haiti through vaccination

Elizabeth C. Lee1, Dennis L. Chao2, Joseph

Lemaitre3, Laura Matrajt4, Damiano Pasetto3, Javier

Perez-Saez3, Flavio Finger5, Andrea Rinaldo3,

Jonathan D. Sugimoto4, M. Elizabeth Halloran4, Ira

M. Longini6, Ralph Ternier7, Kenia Vissieres7, Andrew

S. Azman1, Justin Lessler1, Louise C. Ivers8 1Johns Hopkins Bloomberg School of Public Health,

Baltimore, MD, United States, 2Institute for Disease

Modeling, Bellevue, WA, United States, 3École

Polytechnique Fédérale de Lausanne, Lausanne,

Switzerland, 4Fred Hutchinson Cancer Research

Center, Seattle, WA, United States, 5London School

of Hygiene and Tropical Medicine, London, United

Kingdom, 6University of Florida, Gainesville, FL,

United States, 7Partners In Health/Zanmi Lasante,

Port-au-Prince, Haiti, 8Massachusetts General

Hospital, Boston, MA, United States

LB-5250

Pathogen genomics to inform treatment and

management of shigellosis in resource-poor

settings

Rebecca J. Bengtsson1, Neil Hall2, Sharon M.

Tennant3, Kate S. Baker1 1University of Liverpool, Liverpool, United

Kingdom, 2Earlham Institute, Norwich, United

Kingdom, 3Center for Vaccine Development and

Global Health, Baltimore, MD, United States

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43

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5251

Ocular Chlamydia trachomatis infection and

infectious load among pre-school aged children

within trachoma hyperendemic districts

receiving the SAFE strategy, Amhara region,

Ethiopia

Scott D. Nash1, Ambahun Chernet2, Jeanne

Moncada3, Aisha E.P. Stewart1, Tigist Astale2, Eshetu

Sata2, Mulat Zerihun2, Demelash Gessese2, Berhanu

Melak2, Gedefaw Ayenew2, Zebene Ayele2, Melsew

Chanyalew4, Thomas M. Lietman5, E. Kelly Callahan1,

Julius Schachter3, Zerihun Tadesse2 1The Carter Center, Atlanta, GA, United States, 2The

Carter Center, Addis Ababa, Ethiopia, 3University of

California, San Francisco, CA, United

States, 4Amhara Regional Health Bureau, Amhara,

Ethiopia, 5Proctor Foundation, University of

California, San Francisco, CA, United States

LB-5252

Comparative genomics reveal two distinct

Samoan clades

of Salmonella enterica subsp. enterica serovar

Typhi from 1992-2018

Michael J. Sikorski1, Myron M. Levine2, David A.

Rasko1 1Institute for Genome Sciences, Department of

Microbiology and Immunology, University of

Maryland School of Medicine, Baltimore, MD, United

States, 2Center for Vaccine Development and Global

Health, University of Maryland School of Medicine,

Baltimore, MD, United States

LB-5253

A briefly description of resistance profile and

biofilm production of Pseudomonas

aeruginosa population circulating in Cartagena-

Colombia

Roger Valle-Molinares1, Paola Tatis2, Doris Gomez3 1Programa de Biología, Universidad del Atlántico,

Barranquilla, Colombia, 2Laboratorio UNIMOL,

Universidad de Cartagena, Cartagena,

Colombia, 3Doctorado en Medicina Tropical,

Universidad de Cartagena, Cartagena, Colombia

LB-5254

Antimicrobial Resistance and Molecular

Characterisation of Staphylococcus aureus from

Surgical Site Infections in Ghana

Beverly Egyir1, Jeannette Bentum2, Naiki Attram2,

Anne Fox2, Noah Obeng-Nkrumah3, Labi Appiah-

Korang4, Eric Behene2, Selassie Antwi2, Clara

Yeboah2, Bright Agbodzi2, Ronald Bentil2, Felicia

Owusu2, Nicholas T.K.D Dayie5, Eric S Donkor5,

Kwaku Asa-Opoku6, Edward Nyarko7, Edward

Asumanu7, Anders Rhod Larsen8, David M Wolfe2,

Andrew Letizia2 1Noguchi Memorial Institute for Medical Research

University of Ghana, Accra, Ghana, 2Naval Medical

Research Unit - Three, Ghana Detachment, Accra,

Ghana, 3Department of Medical Laboratory Sciences,

School of Biomedical and Allied Health Sciences,

Accra, Ghana, 4Department of Microbiology, Korle-Bu

Teaching Hospital, Accra, Ghana, 5Department of

Microbiology, University of Ghana Medical School,

University of Ghana, Accra, Ghana, 6Department of

Obstetrics and Gynaecology, Korle-bu Teaching

Hospital, Accra, Ghana, 737 Military Hospital, Accra,

Ghana, 8Statens Serum Institut; Department of

Bacteria, Parasites and Fungi; Reference Laboratory

for Antimicrobial Resistance, Artillerivej 5, DK-2300,

Copenhagen, Denmark

LB-5255

Susceptibility to Campylobacter spp

Gastroenteritis associated with Lewis

Phenotype

Fredman Gonzalez1, Roberto Herrera1, Lester

Gutierrez1, Yaoska Reyes1, Nadja Vielot2, Margarita

Paniagua1, Natalie Bowman2, Johan Nordgren3,

Sylvia Becker-Dreps2, Filemon Bucardo1, Samuel

Vilchez1, The SAGE Team1 1UNAN-Leon, Leon, Nicaragua, 2UNC, Chapel Hill, NC,

United States, 3Linkoping University, Linkoping,

Sweden

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44

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5256

Prevalence, antimicrobial resistance, and

distribution of Shigella among children under

five in three sub-Saharan African countries in

the Vaccine Impact on Diarrhea in Africa study

Henry Badji1, Irene Kasumba2, Sunil Sen2,

Shamima Nasrin2, Jennifer Jones2, Jasnehta Permala-

Booth2, Helen Powell2, M. Jahangir Hossain1, Jennifer

R. Verani3, Marc-Alain Widdowson3, James Platts-

Mills4, Anna Roose2, Richard Omore5, Ben Ochieng5,

Samba Sow6, Sanogo Doh6, Boubou Tamboura6,

Joquina Chiquita M. Jones1, Syed M.A. Zaman1,

Dilruba Nasrin2, Catherine Okoi1, Martin Antonio1, Jie

Liu4, Eric Houpt4, Ciara Sugerman7, Karen L. Kotloff2,

Sharon M. Tennant2 1Medical Research Council Unit The Gambia at the

London School of Hygiene & Tropical Medicine,

Banjul, Gambia, 2Center for Vaccine Development

and Global Health, University of Maryland School of

Medicine, Baltimore, Baltimore, MD, United

States, 3Global Disease Detection Division, Kenya

Office of the US Centers for Disease Control and

Prevention, Nairobi, Kenya, 4Division of Infectious

Diseases and International Health, Department of

Medicine, University of Virginia, Charlottesville, VA,

United States, 5Kenya Medical Research Institute,

Center for Global Health Research, Kisumu,

Kenya, 6Center for Vaccine Development-Mali,

Bamako, Mali, 7Division of Foodborne, Waterborne,

and Environmental Diseases, US Centers for Disease

Control and Prevention, Atlanta, GA, United States

LB-5257

Molecular detection of pathogens in negative

blood cultures in Lao People’s Democratic

Republic

Soo Ter Kai1, Amphone Sengduangphachanh2,

Somsavanh Sihalath2, Sayaphet Rattanavong2,

Tamalee Roberts2, Paul N. Newton2, Andrew

Simpson2, Elizabeth Ashley2, Matthew Robinson2 1London School of Hygiene and Tropical Medicine,

London, United Kingdom, 2Laos-Oxford-Mahosot

Hospital-Wellcome Research Unit, Vientiane, Lao

People's Democratic Republic

LB-5258

Detection of carbapenem-resistant clinical

isolates expressing diverse carbapenemase

genes among high-risk international strains of

gram-negative bacteria in Kenya

Lillian Anyango Musila1, Cecilia Kyany’a1, Daniel

Matano1, Rosslyn Maybank2, Erick Odoyo1, Angela

Nderi3, Martin Georges1, Jason Stam2, Frederick

Tiria1, Valerie Oundo1, Willie Sang4 1USAMRD-A, Nairobi, Kenya, 2Multidrug-resistant

organism Repository and Surveillance Network,

WRAIR, Silver Springs, MD, United States, 3Defense

Forces Memorial Hospital, Nairobi, Kenya, 4Kenya

Medical Research Institute, Nairobi, Kenya

LB-5259

Change in prevalence of risk factors for

diarrhea mortality between across a 10 year

period between Global Enteric Multicenter

Study (GEMS) and Vaccine Impact on Diarrhea

in Africa (VIDA)

Emily L. Deichsel1, Helen Powell1, Adama M. Keita2,

M Jahangir Hossain3, Richard Omore4, Doh Sanogo2,

Samba O. Sow2, Joquina CM Jones3, Anna Roose1,

Dilruba Nasrin1, Jennifer Verani5, Mark-Alain

Widdowson5, Milagritos Tapia1, Karen L. Kotloff1 1University of Maryland, Baltimore, Baltimore, MD,

United States, 2Centre pour le Developpement des

Vaccins du Mali (CVD-Mali), Bamako, Mali, 3Medical

Research Council Unit The Gambia, Banjul,

Gambia, 4Kenya Medical Research Institute/Center

for Global Health Research (KEMRI-CGHR), Kisumu,

Kenya, 5Division of Global Health Protection, Kenya

Office of the US Centers for Disease Control and

Prevention, Nairobi, Kenya

LB-5260

Investigating the risk of spotted fever group

rickettsioses in Texas hunters

Sarah M. Gunter1, Allison Lino1, Alyssa McNulty2,

Rebecca Fischer2, Dorianne Nollet1, Timothy

Erickson1, Shannon E. Ronca1, Alex Carisey1, Kristy

O. Murray1 1Baylor college of Medicine, Houston, TX, United

States, 2Texas A&M School of Public Health, College

Station, TX, United States

LB-5261

Cause-specific mortality in communities treated

with mass azithromycin distributions verbal

autopsy results from a cluster-randomized trial

in Niger

Ahmed M. Arzika

MORDOR PROJECT, NIAMEY, Niger

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45

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5262

Antimicrobial resistance of enteric pathogens in

the Military Health System, 2009 - 2018

Connor Pomeroy1, Mona Baishya1, Myles Johnson2,

Uzo Chukwuma3, Sara Bazaco2, Kathleen Creppage3,

Paul Graf4, Hayley Ashbaugh5 1ORISE fellow, NMCPHC Epi Data Center, Silver

Spring, MD, United States, 2GDIT / Armed Forces

Health Surveillance Branch, Silver Spring, MD,

United States, 3NMCPHC Epi Data Center, Silver

Spring, MD, United States, 4Naval Health Research

Center, San Diego, CA, United States, 5Armed Forces

Health Surveillance Branch, Silver Spring, MD,

United States

LB-5263

Microbiome clusters associated with diarrheal

outcomes are characterized by species

diversity, systemic inflammation and antibiotic

use in a Bangladeshi birth cohort

E Ross Colgate1, Korin M. Eckstrom1, Rashidul

Haque2, Dorothy M. Dickson1, Marya P. Carmolli1,

Ashley K. Miles1, Masud Alam2, Jeffrey I. Gordon3,

William A. Petri4, Beth D. Kirkpatrick1 1University of Vermont College of Medicine,

Burlington, VT, United States, 2International Centre

for Diarrhoeal Disease Research, Bangladesh, Dhaka,

Bangladesh, 3Washington University School of

Medicine, St. Louis, MO, United States, 4University of

Virginia School of Medicine, Charlottesville, VA,

United States

LB-5264

Etiology of fever in returning travelers and

migrants: a systematic review and meta-

analysis

Imogen M. Buss, Blaise Genton, Valérie d'Acremont

Center for Primary Care and Public Health, University

of Lausanne, Lausanne, Switzerland

LB-5265

Challenges in Administration and Monitoring of

Oxygen Therapy in Children with Severe

Pneumonia: A Mixed Methods Study from 14

Hospitals in Ethiopia

Habtamu S. Tolla1, Yigeremu Asemere1, Felix Lam2,

Audrey Battu2, Simret Ameha3 1Clinton Health Access Initiative, Addis Ababa,

Ethiopia, 2Clinton Health Access Initiative, Boston,

MA, United States, 3Federal Ministry of Health, Addis

Ababa, Ethiopia

LB-5266

Evaluation of rodent-proof food storage devices

to reduce human exposure to Rattus rattus and

their fleas inside traditional huts in a plague

endemic region of Uganda

Linda A. Atiku1, Joseph T. Mpanga1, Russell E.

Enscore2, Marc Delory2, Kenneth L. Gage2, Rbecca J.

Eisen2 1Uganda Virus Research Institute, Entebbe,

Uganda, 2US Centers for Disease Control and

Prevention, Fort Collins, CO, United States

LB-5267

A forecast of drug development in developing

countries: a case of Indonesia

Ria Christine Siagian1, Jorge E. Osorio2 1Universitas Indonesia and Badan Pengawas Obat

dan Makanan, Jakarta, Indonesia, 2University of

Wisconsin Madison, Madison, WI, United States

LB-5268

Parasitic infections and medical expenses

according to Health Insurance Review

Assessment claims data in Korea, 2011-2018

Ju Yeong Kim, Tai-Soon Yong

Yonsei University College of Medicine, Seoul, Korea,

Republic of

LB-5269

Incidence of typhoid fever using a hybrid

surveillance system: Results from the SEFI

study

Karthikeyan Ramanujam1, Reshma Raju1, Arun S.

Karthikeyan1, Venkata Raghava Mohan1, Sheena

Ebenezar2, Madhu Gupta3, Ashita Singh4, Dasharatha

Ramaiah5, Anna Alexander6, Roshine Koshy7, Jacob

John1, Gagandeep Kang1 1Christian medical college, Vellore, India, 2Duncan

Hospital, Raxaul, India, 3PGIMER, Chandigarh,

India, 4Chinchpada Christian Hospital, Chinchpada,

India, 5RDT hospital, Bathalapalli, India, 6Lady

Willingdon Hospital, Manali, India, 7Makunda

Christian Leprosy and General Hospital, Makunda,

India

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46

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5270

Lipid-Based Nutritional Supplements Are Not a

Universal Solution for Reducing the Incidence

of Low Birth Weight in Low and Middle-Income

Countries

Alexa M. Rangecroft

Wake Forest School of Medicine, Winston Salem, NC,

United States

LB-5271

Potential For Clinically Significant Drug-Drug

Interactions in Patients with Cancer in Sub-

Saharan Africa

Sarah Elizabeth Lochrin

National Institute of Health, Bethesda, MD, United

States

LB-5272

WAIST CIRCUMFERENCE COMPLEMENTING

BODY MASS INDEX MEASURES ASSESSED AS

NON-COMMUNICABLE DISEASE RISK

INDICATORS IN ADULT WOMEN, A

COMPARISON STUDY IN THE DOMINICAN,

HONDURAS AND EL SALVADOR

Dean Sutphin1, Susan Meacham1, JuliSu Dimucci-

Ward2, Anna Newton3, Maria Jose Lopez4, Fatima

Recinos4, Xiomara Erazo5, Dina Rojas6, Ivin

Vaquando6, Dulfelina Cruz7 1VCOM, Blacksburg, VA, United States, 2VCOM,

Spartanburg, SC, United States, 3VCOM, Auburn, AL,

United States, 4VCOM, San Salvador, El

Salvador, 5VCOM, Tegucigalpa, Honduras, 6UNITEC,

Tegucigalpa, Honduras, 7VCOM, Veron, Dominican

Republic

LB-5273

Supporting local health leadership and

governance towards sustainable malaria

elimination in the southern Philippines through

learning and accountability tools

Dominique Lumapas Monido, Kathrinna Dhay N.

Legaspi

Zuellig Family Foundation, Paranaque City,

Philippines

LB-5274

Trends in reported antibiotic use among sick

children under five years across low- and

middle-income countries in 2005-2017: a

systematic analysis of 132 national surveys

from 73 countries

Gbemisola Allwell-Brown1, Laith Hussain-

Alkhateeb2, Freddy E. Kitutu3, Susanne Strömdahl1,

Andreas Mårtensson1, Emily W. Johansson1 1Uppsala University, Uppsala, Sweden, 2Gothenburg

University, Gothenburg, Sweden, 3Makerere

University, Kampala, Uganda

LB-5275

Prior vaccination with recombinant Vesicular

Stomatitis Virus - Zaire Ebolavirus is associated

with increased survival in patients with

confirmed Ebolavirus disease

Kasereka M. Claude1, Austin D. Ericson2, Michael T.

Hawkes3 1Université Catholique du Graben, Butembo, Congo,

Democratic Republic of the, 2University of Alberta,

Edmonton, AB, Canada, 3Department of Pediatrics,

University of Alberta, Edmonton, AB, Canada

LB-5276

Efficacy of a spatial repellent for control of

malaria in Indonesia: a cluster-randomized

controlled trial

Nicole L. Achee1, Puji B. Asih2, Ismail E. Rozi2,

Dendi H. Permana3, Anggi P. Hidayati2, Lepa

Syahrani2, Siti Zubaidah2, Dian Sidik4, Michael J.

Bangs5, Claus Bøgh6, Fang Liu1, Evercita C. Eugenio1,

Jared Hendrickson1, Timothy Burton1, J Kevin Baird7,

Frank Collins1, John P. Grieco1, Neil F. Lobo1, Din

Syafruddin2 1University of Notre Dame, Notre Dame, IN, United

States, 2Eijkman Institute for Molecular Biology,

Jakarta, Indonesia, 3Eijkman Institute for Molecular,

Jakarta, Indonesia, 4Hasanuddin University,

Makassar, Indonesia, 5International SOS, Kuala

Kencana, Indonesia, 6The Sumba Foundation, Bali,

Indonesia, 7Eijkman-Oxford Clinical Research,

Jakarta, Indonesia

LB-5277

Challenges, opportunities and updates: a focus

on the 2019 Eastern Burma Retrospective

Mortality Survey

Breagh Cheng1, Saw Nay Htoo2, Naw Pue Pue

Mhote2, Colleen Davison1 1Queen's University, Kingston, ON, Canada, 2Burma

Medical Association, Mae Sot, Thailand

Page 48: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

47

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5278

Risk factors for flavivirus infection among long-

term expatriates in Thailand

Erica Rapheal1, Amornphat Kitro2, Hisham Imad2,

Jutarmas Olanwijitwong2, Ali Sawani3, Lapakorn

Chatapat2, Watcharapong Piyaphanee2, Katie

Anderson1 1University of Minnesota, Minneapolis, MN, United

States, 2Mahidol University Hospital of Tropical

Medicine, Bangkok, Thailand, 3University of Central

Florida, Orlando, FL, United States

LB-5279

Evaluating national malaria programs impact in

moderate- and low-transmission settings:

Technical approaches

Debra Prosnitz1, Ruth Ashton2, Andrew Andrada1,

Yazoume Ye1 1ICF, Rockville, MD, United States, 2Tulane

University, New Orleans, LA, United States

LB-5280

Building Global Health Security Workforce and

Research Infrastructure through North-South

Collaboration: The U.S-Nigeria Military

Experience

Laura R. Chittenden1, Michael Iroezindu2, Yakubu

Adamu1, Nathan Okeji3 1U.S. Army Medical Research Directorate-

Africa/Nigeria, WRAIR, Abuja, Nigeria, 2Henry

Jackson Foundation MRI, Abuja, Nigeria, 3Nigeria

Ministry of Defence Health Implementation

Programme, Abuja, Nigeria

LB-5281

Spatial and temporal trends in access and use

for insecticide-treated nets in Africa, 2000-

2018

Amelia Bertozzi-Villa1, Samir Bhatt2, Caitlin

Bever1, Peter Gething3 1Institute for Disease Modeling, Bellevue, WA, United

States, 2Imperial College, London, United

Kingdom, 3Oxford University, Oxford, United

Kingdom

LB-5282

Comparison of TaqMan Array Card malaria

results with conventional malaria testing

among acute febrile patients attending two

health facilities in Montserrado, Liberia, 2019

Elijah Paa Edu-Quansah1, Terrence Lo2, Daniel

Martin2, Barry Fields2, Gulu Gwesa2, Jolie Dennis2,

Lekilay Tehmeh3, John Dogba4, Victoria Katawera5,

Eric Houpt6, Darwin Operario6, Jie Liu6, Maame

Pokuah Amo-Addae1, Davis Ashaba7, Mosoka Fallah4,

Desmond Williams2 1African Field Epidemiology Network, Monrovia,

Liberia, 2US Centers for Disease Control and

Prevention, ATLANTA, GA, United States, 3Ministry of

Health, Monrovia, Liberia, 4National Public Health

Institute of Liberia, Monrovia, Liberia, 5World Health

Organization, Monrovia, Liberia, 6University of

Virginia, Virginia, VA, United States, 7African Field

Epidemiology Network, Kampala, Uganda

LB-5283

Validation of the Dubowitz Neonatal

Neurological Examination in Low-Resource

Settings

Harriet L. S. Lawford1, Mercy A. Nuamah2, Felix

Botchway3, Samuel A. Oppong2, Ali Samba2,

Ebenezer V. Badoe4, Sailesh Kumar1, Anne CC Lee5,

Helen G. Liley1, Richard K. Gyasi6, Andrew A. Adjei6,

Samudragupta Bora1 1Mothers, Babies and Women's Health Program,

Mater Research Institute, Faculty of Medicine, The

University of Queensland, South Brisbane,

Australia, 2Department of Obstetrics and Gynecology,

University of Ghana Medical School, Korle Bu, Accra,

Ghana, 3Central Diagnostic Laboratory, Korle Bu

Teaching Hospital, Accra, Ghana, 4Department of

Child Health, University of Ghana Medical School,

Korle Bu, Accra, Ghana, 5Department of Pediatric

Newborn Medicine, Brigham and Women’s Hospital,

Harvard Medical School, Boston, MA, United

States, 6Department of Pathology, University of

Ghana Medical School, Korle Bu, Accra, Ghana

LB-5284

The impact of socio-health metrics in hair

cortisol concentrations and distress symptoms

in individuals with arboviral illness in Machala,

Ecuador

Denisse Vega Ocasio1, Anna M. Stewart-Ibarra2,

Kestutis G. Bendinskas3, Rachel Sippy2, Timothy D.

Dye1 1University of Rochester Medical Center, Rochester,

NY, United States, 2SUNY Upstate Medical University,

Syracuse, NY, United States, 3State University of

New York at Oswego, Oswego, NY, United States

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48

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5285

Novel point-of-care test for identifying risk of

primary immunodeficiency to support global

polio elimination

Allison L. Golden1, Shirli Israeli1, Ridha Barbouche2,

Melissa C. Atalig1, Najla Mekki2, Afef Rais2, Helen L.

Storey1, Roger B. Peck1 1PATH, Seattle, WA, United States, 2Institut Pasteur

de Tunis, Tunis, Tunisia

LB-5286

Mosquito-borne Disease Impact of

Environmental and Natural Disasters: Lessons

Learned from Brazil and Mozambique

Baltazar Candrinho1, Flavia Ribeiro2, Rita Chico3,

James Colborn3, Falgunee K. Parekh4, Eduardo Gudo5 1Mozambique National Malaria Control Program,

Maputo, Mozambique, 2Centro de Pesquisas Clinicas-

HC/UFMG/EBSERH, Minas Gerais, Brazil, 3Clinton

Health Access Initiative, Maputo,

Mozambique, 4EpiPointe, Cary, NC, United

States, 5Mozambique National Institutes of Health,

National Health Observatory, Maputo, Mozambique

LB-5287

Clinical, parasitological and serological follow

up chronic Chagas disease patients after three

years of intermittent benznidazole

administration

María G. Alvarez1, Graciela Bertocchi1, Marisa

Fernandez2, Yolanda Hernandez2, Bruno Lococo1,

Juan C. Ramirez2, Constanza Lopez Albizu2,

Alejandro Schijman3, Marcelo Abril4, Susana A.

Laucella1, Rick L. Tarleton5, Maria A. Natale2, Melisa

D. Castro Eiro2, Sergio Sosa-Estani6, Rodolfo Viotti1 1Hospital Interzonal de Agudos Eva Peron, Buenos

Aires, Argentina, 2Instituto Nacional de Parasitologia

Dr Mario Fatala Chaben, Buenos Aires,

Argentina, 3Instituto de Ingenieria Genetica y

Biologia Molecular, Buenos Aires, Argentina, 4Mundo

Sano, Buenos Aires, Argentina, 5Center for Tropical

and Emerging Global Diseases, Athens, GA, United

States, 6Instituto de Efectividad Clinica y Sanitaria,

Buenos Aires, Argentina

LB-5288

Detection of a Trypanosoma cruzi Secreted

Antigen in Infected Hosts

Rana Nagarkatti1, David Acosta1, Nirmallya

Acharya1, Fernanda Fortes de Araujo2, Andrea

Taxiera-Carvaho2, Alain Debrabant1 1CBER/FDA, Silver Spring, MD, United

States, 2Fiocruz, Belo Horizonte, Brazil

LB-5289

Chagas disease seroprevalence in pregnant

women from endemic regions attended at

Hospital General de Mexico (Mexico City,

Mexico) and Johns Hopkins Bayview Medical

Center (Baltimore, USA)

Monica Miranda-Schaeubinger1, Kimberly Parra2,

Indira Chakravarti1, Celeste Villanueva-Cabello3,

Jesus Briones Garduño4, Alejandra Borge Villareal4,

Yadira Béjar-Ramírez4, Alejandro Pérez-González4,

Edith Fernández-Figueroa3, Adriana Ruiz-Remigio3,

Heidi Brown2, Eyal Oren5, Ingeborg Becker3, Robert

H. Gilman1 1Johns Hopkins University, Baltimore, MD, United

States, 2Univeristy of Arizona, Tucson, AZ, United

States, 3Universidad Nacional Autonoma de Mexico,

Mexico City, Mexico, 4Hospital General de Mexico,

Mexico City, Mexico, 5San Diego State University,

San Diego, CA, United States

LB-5290

Transfusion Transmitted

Leishmaniasis: Leishmania Detection in the

Blood Supply and Associated Risk Factors

Shareese Clarke1, Ruwandi Kariyawasam2, Rachel

Lau3, Olamide Egbewumi1, Andrea K. Boggild4 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Institute of Medical Sciences,

University of Toronto, Toronto, ON, Canada, 3Public

Health Ontario Laboratories, Toronto, ON,

Canada, 4Tropical Disease Unit, Toronto General

Hospital and University of Toronto, Toronto, ON,

Canada

LB-5291

Reactivation of Tegumentary Leishmaniasis

Following Iatrogenic Immunosuppression: A

Systematic Review of Secondary Prophylaxis

Katherine Tan1, Ruwandi Kariyawasam2, Aisha

Khatib3, Avinash Mukkala2, Christian Lecce3, Celine

Lecce3, Shveta Bhasker3, Eric Shao3, Andrea K.

Boggild4 1Tropical Disease Unit, Toronto General Hospital and

University of Toronto, Toronto, ON,

Canada, 2Institute of Medical Sciences, University of

Toronto, Toronto, ON, Canada, 3Tropical Disease

Unit, Toronto General Hospital, Toronto, ON,

Canada, 4Tropical Disease Unit, Toronto General

Hospital, University of Toronto, Toronto, ON, Canada

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49

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5292

Can We Expand the Diagnostic Capabilities of

the FDA-Cleared CL Detect™ Rapid Test from

Old World to New World Cutaneous

Leishmaniasis?

Christie Alyce Joya1, Ana Ramos2, Luis A. Rosales1,

Maria J. Saenz1, Silvia Revilla1, Gloria Fuentes1,

Edward Smith1, Juan F. Sanchez1, Danett Bishop1,

Alejandro Llanos-Cuentas2, Max Grogl1 1Naval Medical Research No. 6, Lima,

Peru, 2Universidad Peruana Cayetano Heredia, Lima,

Peru

LB-5293

Evaluation of District Health Information

System 2 for malaria surveillance in Solomon

Island

Kinley Wangdi1, John Leaburi2, Emma McBradye3,

Archie C. Clements4 1Australian National University, Canberra,

Austria, 2National Vector Borne Disease Control

Programme, Ministry of Health and Medical Services,

Honiara, Solomon Islands, 3Australian Institute of

Tropical Health & Medicine, James Cooks University,

Townsville, Australia, 4Curtin University, Perth,

Australia

LB-5294

Impact of Mass Drug Administration with

Dihydroartemisinin-Piperaquine on P.

falciparum Antimalarial Resistance and

Gametocytaemia

Himanshu Gupta1, Beatriz Gálatas1, Gloria

Matambisso2, Lidia Nhamussua2, Silvie Huijben2,

Wilson Simone2, Quique Bassat1, Arlindo

Chidimatembue2, Pau Cisteró1, Regina Rabinovich1,

Pedro Luis Alonso1, Francisco Saúte2, Pedro

Aide2, Alfredo Mayor1 1Barcelona Institute for Global Health (ISGlobal),

Barcelona, Spain, 2Manhiça Health Research Center

(CISM), Manhiça, Mozambique

LB-5295

Presence of k13 561H artemisinin resistance

mutations in Plasmodium falciparum infections

in Rwanda, 2018

Aline Uwimana1, Noella Umulisa2, Meera

Venkatesan3, Eric S. Halsey4, Tharcisse

Munyaneza5, Rafiki M. Habimana5, Ryan Sandford6,

Leah Moriarty4, Emily Piercefield7, Zhiyong Zhou4,

Samaly Souza4, Ira Goldman4, Naomi Lucchi4, Brian

Ezema4, Eldin Talundzic4, Daniel Ngamije8, Jean-

Louis N. Mangala1, William Brieger9, Venkatachalam

Udhayakumar4, Aimable Mbituyumuremyi1 1Malaria and Other Parasitic Diseases Division,

Rwanda Biomedical Centre, Kigali,

Rwanda, 2Maternal and Child Survival Program,

JHPIEGO, Baltimore, MD, United States, 3US

President’s Malaria Initiative, USAID, Washington,

DC, United States, 4Malaria Branch, Centers for

Disease Control and Prevention, Atlanta, GA, United

States, 5National Reference Laboratory, Rwanda

Biomedical Centre, Kigali, Rwanda, 6US Peace Corps,

Kigali, Rwanda, 7Malaria Branch, Centers for Disease

Control and Prevention, Kigali, Rwanda, 8WHO

Rwanda Office, Malaria and Neglected Tropical

Diseases Programs, Kigali, Rwanda, 9The Johns

Hopkins University, Bloomberg School of Public

Health, Department of International Health,

Baltimore, MD, United States

LB-5296

Formative Assessment to Understand and

Target High Malaria Risk Populations in

Vietnam and Cambodia

Valerie K. Scott1, Andrew A. Lover2, Jennifer L.

Smith1, Tran Thanh Duong3, Ngô Đức Thắng3, Xuan

Thang Nguyen3, Siv Sovonnaroth4, Andrew Martin5,

Adam Bennett1 1Malaria Elimination Initiative, Global Health Group,

University of California at San Francisco, San

Francisco, CA, United States, 2University of

Massachussetts-Amherst, Amherst, MA, United

States, 3Viet Nam National Institute of Malaria,

Parasitology, and Entomology (NIMPE), Hanoi, Viet

Nam, 4Cambodia National Center for Parasitology

Entomology and Malaria Control (CNM), Phnom

Penh, Cambodia, 5Health Poverty Action, Phnom

Penh, Cambodia

LB-5297

Mobile qPCR for malaria surveillance in Ethiopia

Werissaw Haileselassie1, Lise Carlier2, Sarah Cate

Baker2, Cristian Koepfli3 1Addis Ababa University, Addis Ababa,

Ethiopia, 2Trinity College, Dublin, Ireland, 3University

of Notre Dame, Notre Dame, IN, United States

LB-5298

Primaquine as radical cure for tropical vivax -

development of an optimised weight and age

based dose regimen

Walter Taylor, Richard M. Hoglund, Pimnara

Peerawaranun, Joel Tarning, Mavuto Mukaka

MORU, Bangkok, Thailand

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50

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5299

“There is no one whom I talk to”: Experiences

and support needs after hospital discharge of

primary caregivers of cerebral malaria

survivors with behavior problems in Blantyre,

Malawi

Savannah Karmen-Tuohy1, Sebastian Mboma2,

John T. Langfitt3, Rachel Brim4, Melissa Gladstone5,

Terrie E. Taylor4 1New York University School of Medicine, New York,

NY, United States, 2Blantyre Malaria Project, College

of Medicine, University of Malawi, Blantyre,

Malawi, 3Department of Neurology, School of

Medicine and Dentistry, University of Rochester,

Rochester, NY, United States, 4Department of

Osteopathic Medical Specialties, College of

Osteopathic Medicine, Michigan State University,

East Lansing, MI, United States, 5Department of

Women and Children's Heath, Institute of

Translational Medicine, University of Liverpool,

Liverpool, United Kingdom

LB-5300

Evaluation of a new outdoor vector control tool

against malaria: the design of an

epidemiological efficacy trial of Attractive

Targeted Sugar Baits

Mahamoudou Toure1, Immo Kleinschmidt2, Sophie

Sarrassat2, Mohamed Traore1, John Bradley2, Gunter

Muller1, Silas Majambere3, John C. Beier4, John

Vontas5, Sekou F. Traore1, Madeleine Beebe1, Megan

Littrell6, Samba Diop1, Seydou Doumbia1 1University Clinical Research Center/ University of

Sciences, Techniques and Technologies of Bamako,

Bamako, Mali, 2London School of Hygiene and

Tropical Medicine, London, United Kingdom, 3Pan-

African Mosquito Control Association, Nairobi,

Kenya, 4University of Miami Miller School of Medicine,

Miami, FL, United States, 5Institute of Molecular

Biology & Biotechnology/ Foundation for Research

and Technology – Hellas, Athens, Greece, 6PATH,

Washington, DC, United States

LB-5301

Phase 2 double-blind, family compound

randomized, comparator-controlled trial of

Pfs230D1M-EPA/AS01: Vaccine community trial

progress and pilot results

Issaka Sagara1, Sara A. Healy2, Jennifer Kwan3,

Abdoulaye Katile1, Bourama Kamate1, Mamady

Kone1, Jonathan Fintzi4, Bruce Swihart4, Mahamadou

S. Sissoko1, Amatigue Zeguime1, Kelly M. Rausch2,

David L. Narum2, Puthupparampil Scaria2, Nicholas J.

MacDonald2, Daming Zhu2, Daman Sylla1, Mamadou

Coulibaly1, Jen C. Hume2, Amagana Dolo1, Sekou F.

Traore1, Patrick E. Duffy2 1MRTC, Bamako, Mali, 2LMIV, NIAID/NIH, Bethesda,

MD, United States, 3LCIM, NIAID/NIH, Bethesda, MD,

United States, 4BRB, NIAID/NIH, Rockville, MD,

United States

LB-5302

Evaluation of a Pfs230D1M-OMPC Conjugate

in Rhesus as a Transmission-Blocking Vaccine

against Malaria

Christopher G. Rowe1, Beth B. Chen1, Emma K.

Barnafo1, Nada A. Alani1, Olga V. Muratova1, Brandi

L. Butler1, Lynn E. Lambert1, Charles F. Anderson2,

Irfan Zaidi1, David L. Narum1, Zoltan Beck3, Gary R.

Matyas3, Debbie D. Nahas4, Bob J. Lucas4, Patrick E.

Duffy1, Puthupparampil V. Scaria1 1Laboratory of Malaria Immunology & Vaccinology,

NIAID, National Institutes of Health, Bethesda, MD,

United States, 2Laboratory of Parasitic Diseases,

NIAID, National Institutes of Health, Bethesda, MD,

United States, 3U.S. Military HIV Research Program,

Walter Reed Army Institute of Research, Silver

Spring, MD, United States, 4Vaccines & Infectious

Diseases, Merck & Co., Inc., Kenilworth, NJ, United

States

LB-5303

Strengthening malaria microscopy at national

and provincial levels in the Democratic

Republic of the Congo (DRC) through refresher

trainings

Pharath Lim1, Ange Landela2, Anselme Manyong2,

Seraphine Kutumbakana2, Lennie Kyomuhangi1, Ricki

Orford3, Daouda Ndiaye1, Aboubacar Sadou4,

Godefroid Tshiswaka4, Dieudonne Ngoya5, Eric

Mukomena5 1Medical Care Development International, Silver

Spring, MD, United States, 2Medical Care

Development International, Kinshasa, Congo,

Democratic Republic of the, 3PSI, Washington, DC,

United States, 4PMI, Kinshasa, Congo, Democratic

Republic of the, 5DRC Ministry of Health, Kinshasa,

Congo, Democratic Republic of the

LB-5304

Isolation, purification and characterization of

natural Plasmodium falciparum histidine-rich

protein-2 from infected RBCs

Balwan Singh, Eric Rogier, Amy Kong, Sayan

Chatterjee, Michael Aidoo, Venkatachalam

Udhayakumar

Centers for Disease Control and Prevention, Atlanta,

GA, United States

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51

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5305

Malaria in pregnancy and adverse birth

outcomes are associated with altered

angiogenic and inflammatory factors in both

maternal and fetal circulations

Clara Erice, Andrea Weckman, Melissa Richard-

Greenblatt, Victoria Pierce, Kathleen Zhong, Chloe

McDonald, Kevin C. Kain

Sandra Rotman Centre for Global Health, University

Health Network-University of Toronto, Toronto, ON,

Canada

LB-5306

Understanding private provider motivation to

test and treat malaria in areas with declining

caseloads in the Greater Mekong Subregion

Morgan Brown1, Jennifer Wheeler1, Sochea Phok2,

Saysana Phanalasy3, Si Thu Thien4, Tuan Nguyen

Quoc5, Lorina McAdam6 1Population Services International, Washington, DC,

United States, 2Population Services International

Cambodia, Phnom Penh, Cambodia, 3Population

Services International Laos, Vientienne, Lao People's

Democratic Republic, 4Population Services

International Myanmar, Yangon,

Myanmar, 5Population Services International

Vietnam, Hanoi, Viet Nam, 6Population Services

International, Yangon, Myanmar

LB-5307

Movement patterns of children participating in

a transmission blocking vaccine trial

Jennifer Kwan1, Bronner Goncalves2, Abdoulaye

Ongoiba3, Kadara Kone3, Kelly M. Searle4, Jon Fintzi5,

Issaka Sagara3, Sara A. Healy2, Patrick E. Duffy2 1LCIM, NIAID/NIH, Bethesda, MD, United

States, 2LMIV, NIAID/NIH, Bethesda, MD, United

States, 3MRTC, Bamako, Mali, 4University of

Minnesota School of Public Health, Minneapolis, MN,

United States, 5BRB, NIAID/NIH, Rockville, MD,

United States

LB-5308

Antibody decay profile of a novel transmission

blocking vaccine

Jonathan Fintzi1, Bruce Swihart1, Jennifer Kwan2,

Charles Anderson3, Issaka Sagara4, Sara A. Healy3,

Patrick E. Duffy3 1BRB, NIAID/NIH, Rockville, MD, United

States, 2LCIM, NIAID/NIH, Bethesda, MD, United

States, 3LMIV, NIAID/NIH, Bethesda, MD, United

States, 4MRTC, Bamako, Mali

LB-5309

Assessing the effect of not implementing SMC

on malaria burden as captured by routine data:

the example of Senegal, 2018

MEDOUNE NDIOP, Alioune Badara GUEYE,

Seynabou GAYE, Moustapha CISSE, DOUDOU SENE

National Malaria Control Programm, Dakar, Senegal

LB-5310

Analysis of Malaria Deaths in Senegal 2017

Alioune B. Gueye1, Katharine Sturm-Ramirez2,

Medoune Ndiop1, Seynabou GAYE1, Moustapha

CISSE1, Doudou SENE1 1National Malaria Control Program, Dakar,

Senegal, 2U.S. President’s Malaria Initiative, US

Centers for Disease Control and Prevention, Dakar,

Senegal, Dakar, Senegal

LB-5311

Scaling up subnational leadership and

management for malaria elimination in

Zimbabwe

Roly Gosling1, Amanda Chung1, Peter Case2,

Jonathan Gosling3, Munashe Madinga4 1UCSF, San Francisco, CA, United States, 2University

of West of England, Bristol, United

Kingdom, 3University of Exeter, Exeter, United

Kingdom, 4CHAI, Harare, Zimbabwe

LB-5312

Assessment of Gametocyte Diversity on Malaria

Transmission in Asymptomatic Plasmodium

falciparum Carriers in Senegal

Aminata LAM, Aminata Collé LO, Ndeye Aida GAYE,

Seyda TRAORE, Doudou SOW, Roger Clément TINE,

Babacar FAYE

UCAD/Dakar, Dakar, Senegal

LB-5313

Spatio-temporal dynamics of malaria to inform

and optimize control interventions

Drissa Coulibaly, Boureima Guindo, Salimata

Konate, Amadou Niangaly, Karim Traore, Youssouf

Tolo, Faycal Maiga, Astou Diallo, Mohamed A.

Tahirou, Ogobara Doumbo†, Mahamadou A. THERA

MRTC/DEAP/FMOS - USTTB, Bamako, Mali

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52

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5314

Platelet a-granules promote malaria

immunopathology

Franklin Mvo Maloba1, Thayer Darling1, Michael

Schenk2, Chengjing Zhou3, Patrice Mimche1,

Jonathan M. Gibbins2, Shawn M. Jobe4, Franklin

Maloba1, Tracey Lamb1 1University of Utah, Salt Lake City, UT, United

States, 2University of Reading, UK, Reading, United

Kingdom, 3Emory University, Atlanta, GA, United

States, 4Blood Center of Wisconsin, Milwaukee,

Milwaukee, WI, United States

LB-5315

Characterization of ex vivo Sensitivity of

Proteasome Inhibitors in Ugandan Plasmodium

falciparum isolates

Sevil Chelebieva1, Patrick K. Tumwebaze2, Oswald

Byaruhanga2, Martin Okitwi2, Stephen Orena2,

Stephanie A. Rasmussen1, Liselle F. Guiang3, Daniel

J. Mota3, Ryan M. Scales3, Judith I. Okoro4, Samuel

L. Nsobya2, Melissa D. Conrad3, Ozkan Aydemir5,

Jeffrey A. Bailey5, Wenhu Zahn6, Hao Zhang6, Gang

Lin6, John Ginn7, Nigel Liverton7, Peter Meinke7, Brett

R. Bayles1, Laura A. Kirkman6, Philip J. Rosenthal3,

Roland A. Cooper1 1Dominican University, San Rafael, CA, United

States, 2Infectious Diseases Research Collaboration,

Kampala, Uganda, 3University of California, San

Francisco, San Francisco, CA, United

States, 4University of California, Berkeley, Berkeley,

CA, United States, 5Brown University, Providence, RI,

United States, 6Weill Cornell Medicine, New York, NY,

United States, 7Tri-Institutional Therapeutics

Discovery Institute, New York, NY, United States

LB-5316

Mounting the effects of an indoor residual

spraying intervention on the reservoir

of Plasmodium falciparum in an area

characterised by seasonal transmission in

Ghana.

Kathryn E. Tiedje1, Abraham R. Oduro2, Oscar

Bangre2, Lucas Amenga-Etego3, Samuel K. Dadzie4,

Maxwell Appawu4, Victor Asoala2, Shazia Ruybal-

Pésantez1, Charles A. Narh1, Anita Ghansah4, Samuel

A. Agyei5, Keziah Malm6, Mercedes Pascual7, Kwadwo

A. Koram4, Karen P. Day1 1The University of Melbourne, Bio21 Molecular

Science and Biotechnology Institute, Parkville,

Australia, 2Navrongo Health Research Centre, Ghana

Health Service, Navrongo, Ghana, 3West African

Centre for Cell Biology of Infectious Pathogens,

University of Ghana, Legon, Ghana, 4Noguchi

Memorial Institute for Medical Research, University

of Ghana, Legon, Ghana, 5AngloGold Ashanti

(Ghana) Malaria Control Programme, Obuasi,

Ghana, 6National Malaria Control Programme, Accra,

Ghana, 7Department of Ecology and Evolution,

University of Chicago, Chicago, IL, United States

LB-5317

Assessing mosquito net population access and

use 2 years after a universal distribution

campaign in Angola

Jose Franco Martins1, Hunter Harig2, Hannah

Koenker2, Bolanle Olapeju2, Eliane Mbounga3,

Ricardo Yava4, Anya Fedorova4, BENJAMIN NIETO-

ANDRADE4 1National Malaria Control Program, Luanda,

Angola, 2President's Malaria Initiative - Vector Works

Project, Johns Hopkins Bloomberg School of Public

Health Center for Communication Programs,

Baltimore, MD, United States, 3President's Malaria

Initiative & United States Agency for International

Development, Luanda, Angola, 4Health for All

Project, Population Services International &

President's Malaria Initiative VectorWorks Project,

Luanda, Angola

LB-5318

A Phase III Cluster Randomized Controlled

Trial of In2CareEaveTubes as a new malaria

vector control intervention in an area with

intense pyrethroid resistance

Marit Farenhorst1, Matthew B. Thomas2, Eleanore

D. Sternberg2, Jackie Cook3, Raphael N'Guessan4 1Department of Research, In2Care BV, Wageningen,

Netherlands, 2Department of Entomology and Center

for Infectious Disease Dynamics, The Pennsylvania

State University, State College, PA, United

States, 3MRC Tropical Epidemiology Group,

Department of Infectious Disease Epidemiology,

London School of Hygiene and Tropical Medicine,

London, United Kingdom, 4Institut Pierre Richet (IPR)

/ Institut National de Santé Publique (INSP), Bouaké,

Côte D'Ivoire

LB-5319

The relative abundance of falciparum and vivax

malaria as countries approach local elimination

Mara D. Kont, Benjamin C. Lambert, Thomas S.

Churcher

Imperial College London, London, United Kingdom

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53

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5320

Rationale and construct design for two second

generation CSP vaccines

Sheetij Dutta, Monica Martin, Alexis Bitzer, Andrew

Schrader, Elke Bergmann-Leitner, Farhat Khan, Mark

Langowski, Xiaoyan Zou, Evelina Angov, Viseth

Ngauy, Zoltan Beck, Gary Matyas

WRAIR, Silver Spring, MD, United States

LB-5321

DRONES to Defeat MALARIA

Thomas Kline

Kline Health Group, Redondo Beach, CA, United

States

LB-5322

New Antimalarial Drug Discovery in India and

Future Strategy for Malaria Control

Guru Prakash Dutta

Central Drug Research Institute, Lucknow, India

LB-5323

Feasibility of Door-to-Door Mobile Data

Collection for Indoor Residual Spray (IRS)

Operations Decision Making

Alexia W. Mshambala

Abt Associates, Kisumu City, Kenya

LB-5324

Decentralised approach to outreach training

and supportive supervision (OTSS) expands

reach or malaria case management while

strengthening systems in Zambia

James J. Banda1, Caroline Phiri1, Chabu Kangale1,

Wajilovia Chilambo2 1PATH, Lusaka, Zambia, 2National Malaria Elimination

Centre, Lusaka, Zambia

LB-5325

Systematic Approach to the Review of Malaria

Management Guidelines Ghana, 2019

Akosua Gyasi1, Mildred Komey2, James Sarkodie2,

Keziah Malm1, Raphael Ntumy2, Gladys Teteh3

1Ghana National Malaria Control Program, Accra,

Ghana, 2PMI Impact Malaria Project, Accra,

Ghana, 3Jhpiego, Baltimore, MD, United States

LB-5326

Systematic review evaluating the factors

influencing estimates of long-lasting

insecticidal net efficacy from experimental hut

trials in Africa

Rebecca K. Nash1, Ellie Sherrard-Smith1, Mark

Rowland2, Thomas S. Churcher1 1Imperial College London, London, United

Kingdom, 2London School of Hygiene and Tropical

Medicine, London, United Kingdom

LB-5327

Intercurrent Flaviviral Viremia and Plasmodium

ovale Infection in Ill Returned Travelers to

Ontario

Ruwandi Kariyawasam1, Katherine Tan2, Rachel

Lau3, Filip Ralevski3, Andrea K. Boggild2 1Institute of Medical Sciences, University of Toronto,

Toronto, ON, Canada, 2Tropical Disease Unit, Toronto

General Hospital, Toronto, ON, Canada, 3Public

Health Ontario Laboratories, Toronto, ON, Canada

LB-5328

The Luminex platform for monitoring low

transmission areas aiming at the control and

elimination of malaria

Maria Carmen A. Sanchez1, Ruth T. Portillo1,

Mussya C. Rocha1, Giselle F. Lima1, Angelica D.

Hristov1, Alfredo Mendrone Junior2, José E. Levi1,

Silvia M. Di Santi1 1São Paulo University, São Paulo, Brazil, 2Pró-Sangue

Foundation, São Paulo, Brazil

LB-5329

Loop-mediated isothermal amplification for the

detection of Plasmodium in asymptomatic

individuals harboring low parasitemia as a

molecular tool for control and elimination

programs

Silvia M. Di Santi1, Maria de Lourdes Farinas1,

Mariana Aschar1, Maria de Jesus C. Nascimento2,

Angelica D. Hristov1, Juliana Inoue1, Giselle F. Lima1,

Maria Carmen A. Sanchez1 1São Paulo University, Sao Paulo, Brazil, 2SUCEN,

Sao Paulo, Brazil

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54

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5330

Malaria Research In The Democratic Republic of

congo From 2014 To 2018: A Systematic

Review

SOLANGE E. UMESUMBU

National malaria control program, KINSHASA, Congo,

Democratic Republic of the

LB-5331

Clusters of severe acute respiratory infections

identified through hospital-based influenza

sentinel surveillance in Bangladesh, 2011-2018

Md Ariful Islam1, Md Zakiul Hassan1, Mohammad

Abdul Aleem1, Zubair Akhtar1, Probir Kumar Ghosh1,

Md Mustafizur Rahman1, Mohammed Ziaur Rahman1,

Mahmudur Rahman1, Syeda Mah-E-Muneer1, A

Danielle Iuliano2, Joshua Mott2, Eduardo Azziz-

Baumgartner2, M Salim Uzzaman3, Meerjady Sabrina

Flora3, Fahmida Chowdhury1 1icddr,b, Dhaka, Bangladesh, 2Centers for Disease

Control and Prevention, Atlanta, GA, United

States, 3Institute of Epidemiology, Disease Control

and Research, Dhaka, Bangladesh

LB-5332

Cough Dynamics in Adults Receiving

Tuberculosis Treatment

Richard A. Oberhelman1, Gwenyth O. Lee1,

Germán Comina1, Gustavo Hernandez-Cordova1,

Nehal Naik2, Oscar Gayoso3, Eduardo Ticona4, Jorge

Coronel5, Carlton A. Evans5, Mirko Zimic5, Valerie A.

Paz-Soldan1, Robert H. Gilman6 1Tulane School of Public Health and Tropical

Medicine, New Orleans, LA, United States, 2Virginia

Commonwealth University School of Medicine,

Richmond, VA, United States, 3Hospital Nacional

Cayetano Heredia, Lima, Peru, 4Hospital Nacional

Dos de Mayo, Lima, Peru, 5Universidad Peruana

Cayetano Heredia, Lima, Peru, 6Johns Hopkins

Bloomberg School of Public Health, Baltimore, MD,

United States

LB-5333

Association Between Wheeze and Rhinovirus,

RSV, and Other Pathogens Among Children

Under 5 Hospitalized with Severe Pneumonia in

Africa and Asia

Macall Leslie1, W. Abdullah Brooks1, Maria Deloria

Knoll1, Stephen R. Howie2, Karen Kotloff3, Daniel

Feikin1, Shabir Madhi4, Katherine L. O'Brien5,

Christine Prosperi1, the PERCH Study Group6 1Johns Hopkins Bloomberg School of Public Health,

Baltimore, MD, United States, 2University of Aukland,

Aukland, New Zealand, 3University of Maryland

School of Medicine, Baltimore, MD, United

States, 4University of the Witwatersrand,

Johannesburg, South Africa, 5World Health

Organization, Geneva, Switzerland, 6MD, United

States

LB-5334

Effects of Air Quality on the Epidemiology of

Outpatient Respiratory Viral Infections in

Young Ecuadorean Children

Sarah Ruthen, Rachel Sippy, Cinthya Cueva

Aponte, Cynthia A. Bonville, Joseph B. Domachowske

SUNY Upstate Medical University, Syracuse, NY,

United States

LB-5335

Epidemiologic and Geospatial Analysis of

Pediatric Tuberculosis in Bohol, Philippines

Lauren Leining

Baylor College of Medicine, Houston, TX, United

States

LB-5336

Epidemiology and Treatment of Tuberculosis in

El Oro Province of Ecuador

Michael Joseph Conroy1, Rachel Sippy1, Robinson

Jaramillo2, Tania Ordonez2, Gonzalo Loayza2,

Elizabeth Harausz1, Anna Stewart Ibarra1 1SUNY Upstate Medical University, Syracuse, NY,

United States, 2Ministerio de Salud Publica, Machala,

Ecuador

LB-5337

Hospital surveillance for severe respiratory

infection in Cartagena - Colombia

DORIS ESTHER GOMEZ, JUAN QUINTERO, JORGE

EGURROLA, DEIVIS VILLANUEVA

Universidad de Cartagena, Cartagena, Colombia

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55

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5338

Treatment of Schistosomiasis in Pregnancy: A

Systematic Review of Fetal and Infant

Outcomes

Hira Raheel1, Rachel Lau2, Shveta Bhasker1, Chelsia

Watson1, Gelila Alemayheu1, Robert B. Chris1, Swana

Kopalakrishnan1, Leila Makhani1, Sharmistha Mishra3,

Andrea K. Boggild4 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Public Health Ontario

Laboratories, Toronto, ON, Canada, 3LI Ka Shing

Knowledge Institute, St. Michaels Hospital, Toronto,

ON, Canada, 4Tropical Disease Unit, Toronto General

Hospital, University of Toronto, Toronto, ON, Canada

LB-5339

Unusual Complications of Acute

Schistosomiasis in Travelers

Asaf Biber1, Neta Petersil2, Ami Neuberger3, Eli

Schwartz1 1The Chaim Sheba medical center, Ramat Gan,

Israel, 2Rambam Medical Center, Haifa,

Israel, 3Rambam Medical Cente, Haifa, Israel

LB-5340

Repurposing drugs for treatment of Ebola virus

infections: amodiaquine and amiodarone

Julie Dyall1, Lisa Evans DeWald1, Joshua C.

Johnson1, Anna N. Honko1, Dawn M. Gerhardt1, Lisa

M. Torzewski1, Krisztina Janosko1, Louis Huzella1, Brit

J. Hart1, Elena Postnikova1, Yu Cong1, Huanying

Zhou1, Steven Kern2, William E. Dowling3, Ann E.

Eakin3, Blaire L. Osborn3, Kathleen G. O’Loughlin4,

Carol E. Green4, Janet Gahagen4, Liang Tang4, Jon C.

Mirsalis4, Richard S. Bennett1, Gene G. Olinger1,

Michael R. Holbrook1, Peter B. Jahrling1, Lisa E.

Hensley1 1Integrated Research Facility, Frederick, MD, United

States, 2Bill & Melinda Gates Foundation, Seattle,

WA, United States, 3DMID, NIAID, NIH, Rockville,

MD, United States, 4SRI International, Menlo Park,

CA, United States

LB-5341

Correlation between Dengue History Interview

and Seropositivity in Rural Thailand

Darunee Buddhari1, Kathryn B. Anderson2, Sopon

Iamsirithaworn3, Butsaya Thaisomboonsuk1,

Taweewun Hunsawong1, Gregory D. Gromowski4,

Richard G. Jarman4, Anon Srikiatkhachorn5, Alan L.

Rothman5, Anthony R. Jones1, Stefan Fernandez1,

Stephen J. Thomas2, Timothy P. Endy2 1Department of Virology, USAMD-AFRIMS, Bangkok,

Thailand, 2State University of New York, Syracuse,

NY, United States, 3Ministry of Public Health,

Nonthaburi, Thailand, 4Walter Reed Army Institute of

Research, Silver Spring, MD, United

States, 5University of Rhode Island, Providence, RI,

United States

LB-5342

Laboratory Analysis of Arbovirus Surveillance

in Southern Thailand from 2012-2019

BUTSAYA K. THAISOMBOONSUK1, Sarunyou

Chusri2, Chonticha Klungthong1, Winai Kaneechit1,

Kedsara Tayong1, Piyawan Chinnawirotpisan1,

Yongyuth Poolpanichupatam1, Prinyada Rodpradit1,

Taweewun Hunsawong1, Prapapun Ong-ajchaowlerd1,

Rungarun Suthangkornkul1, Jindarat Lohachanakul1,

Thanaporn Hortiwakul2, Thongchai Khiankaew1,

Chutithorn Tawilert1, Kanittha Sirikajornpan1, Ananda

Nisalak1, Richard G. Jarman3, In-Kyu Yoon4, Anthony

R. Jones1, Kathryn B. Anderson1, Damon W. Ellison3,

Alden L. Weg1, Louis R. Macareo1, Stefan Fernandez1 1Armed Forces Research Institute of Medical Sciences

(AFRIMS), BANGKOK, Thailand, 2Department of

Medicine, Prince of Songkla University (PSU), Hat

Yai, Thailand, 3Department of Virus Diseases, Walter

Reed Army Institute of Research (WRAIR), Bethesda,

MD, United States, 4International Vaccine Institute

(IVI), Seoul, Korea, Republic of

LB-5343

External Validation in the Democratic Republic

of Congo of the Ebola Prediction Score for Risk

Stratification of Patients With Suspected Ebola

Virus Disease

Adam R. Aluisio1, Alexis Kearney1, Razia Laghari2,

Cimanuka Germain2, Mbong Eta Ngole2, Rigo F.

Muhayangabo2, Stephanie Garbern1, Logan Abel1,

Andreas Colubri3, Jean-Jacques Muyembe4, Adam C.

Levine1 1Warren Alpert Medical School, Brown University,

Providence, RI, United States, 2International Medical

Corps, Los Angeles, CA, United States, 3Broad

Institute of MIT and Harvard University, Cambridge,

MA, United States, 4Institut National pour la

Recherche Biomedicale, Kinshasa, Democratic

Republic of the Congo

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56

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5344

A Single Amino Acid Change Impacts the

Immunogenicity and Efficacy of Modified

mRNA-Based Zika Vaccines in Pre-Clinical

Animal Models

Kapil Bahl1, Brooke Bollman1, Hamilton Bennett1,

Scott Butler2, Kimberly Dowd3, Kaitlyn Morabito3, Ted

Pierson3, Barney S. Graham3, Andrea Carfi1 1Moderna, Inc., Cambridge, MA, United

States, 2Former Employee of Moderna, Inc.,

Cambridge, MA, United States, 3National Institute of

Allergy and Infectious Diseases, Rockville, MD,

United States

LB-5345

CYD-TDV Dengue Vaccine: Alternative

Vaccination Schedules with Reduced Number of

Doses in Healthy Individuals Aged 9 to 50

Years in Latin America and Asia-Pacific Regions

Diana Coronel1, Juliana Park2, Eduardo Lopez-

Medina3, Maria Rosario Capeding4, Andres Cadena5,

Maria Cecilia Montalban6, Isabel Ramirez7, María Liza

Antoinette Gonzales8, Carlos A DiazGranados9,

Betzana Zambrano10, Gustavo Dayan9, Stephen

Savarino11, Zhenghong Chen12, Hawk Wang12, Sunny

Sun12, Matthew Bonaparte11, Andrey Rojas13, Jenny

Carolina Ramirez13, Mae Ann Verdan14, Fernando

Noriega11 1Sanofi Pasteur, Mexico City, Mexico, 2Sanofi

Pasteur, Singapore, Singapore, 3Centro de Estudios

en Infectología Pediátrica (CEIP), and Universidad

del Valle, Cali, Colombia, 4Research Institute for

Tropical Medicine (RITM), Manila, Philippines, 5Clinica

de la Costa, Barranquilla, Colombia, 6Manila Doctors

Hospital (MDH), Manila, Philippines, 7Unidad de

Investigaciones y Docencia Hospital Pablo Tobón

Uribe, Medellin, Colombia, 8University of the

Philippines Manila - Philippine General Hospital (UP-

PGH), Manila, Philippines, 9Sanofi Pasteur, Swifwater,

PA, United States, 10Sanofi Pasteur, Montevideo,

Uruguay, 11Sanofi Pasteur, Swiftwater, PA, United

States, 12Sanofi Pasteur, Beijing, China, 13Sanofi

Pasteur, Bogota, Colombia, 14Sanofi Pasteur, Manila,

Philippines

LB-5346

Sialidase inhibition by oseltamivir phosphate

has no effect on platelet recovery or markers of

plasma leakage in dengue: a double blind,

multicenter, randomized controlled trial

Rahajeng Tunjungputri1, Setyo Pramudo2, Silvita

Riswari3, Bachti Alisjahbana4, M. Hussein Gasem5,

Andre J. van der Ven6, Quirijn de Mast6

1Center for Tropical and Infectious Disease

(CENTRID), Faculty of Medicine Diponegoro

University, Dr Kariadi Hospital, Semarang,

Indonesia, 2Center for Tropical and Infectious

Disease (CENTRID), Faculty of Medicine Diponegoro

University, Semarang, Indonesia, 3Clinical Infectious

Disease Research Center, Faculty of Medicine,

Universitas Padjadjaran, Bandung,

Indonesia, 4Infectious Disease Research Center,

Faculty of Medicine, Universitas Padjadjaran and

Hasan General Sadikin Hospital, Bandung,

Indonesia, 5Center for Tropical and Infectious

Disease (CENTRID), Faculty of Medicine Diponegoro

University, Semerang, Indonesia, 6Radboud

university medical centre, Nijmegen, Netherlands

LB-5347

DENV-2 encephalitis in children from Neiva,

Southern Colombia DEN-2 Encefaliti

Doris S. Salgado

Universidad Surcolombiana,student college the

forest, NEIVA, Colombia

LB-5348

Neurodevelopment alterations in children

prenatally exposed to Zika virus infection, in

southern Colombia

Martha Rocio Vega

Universidad Surcolombiana,student college the

forest, NEIVA, Colombia

LB-5349

Prior vaccination with rVSV-ZEBOV reduces

mortality in patients with laboratory-confirmed

Ebola Virus Disease in the Democratic Republic

of Congo

Alexis S. Kearney1, Adam R. Aluisio1, Razia

Laghari2, Cimanuka Germain2, Mbong Eta Ngole2,

Rigo Fraterne Muhayangabo2, Logan Abel1, Andreas

Colubri3, Jean-Jacques Muyembe4, Adam C. Levine1 1Warren Alpert Medical School of Brown University,

Providence, RI, United States, 2International Medical

Corps, Los Angeles, CA, United States, 3Broad

Institute of MIT and Harvard, Cambridge, MA, United

States, 4Institut National pour la Recherche

Biomedicale, Kinshasa, Democratic Republic of the

Congo

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57

Poster Session B

Late-Breakers in Clinical and Applied Sciences

Friday, November 22, Noon - 1:45 p.m.

LB-5350

Discovery and characterization of a novel

potent pan-serotype dengue virus inhibitor

exhibiting unprecedented in vivo potency by

blocking the NS3/NS4B interaction

Suzanne J. Kaptein1, Olivia Goethals2, Dominik

Kiemel3, Arnaud Marchand4, Tim Jonckers5, Jean-

François Bonfanti6, Dorothée Bardiot4, Bart

Kesteleyn5, Bart Stoops7, Kai Dallmeier1, Laurent

Chatel-Chaix3, Max Münster3, Gilles Querat8, Frank

Touret8, Xavier de Lamballerie8, Pierre Raboisson9,

Kenny Simmen2, Patrick Chaltin4, Ralf

Bartenschlager3, Marnix Van Loock10, Johan Neyts1 1Department of Micorbiology, Immunology and

Transplantation; Rega Institute for Medical Research,

Laboratory of Virology and Chemotherapy; University

of Leuven, Leuven, Belgium, 2Janssen Infectious

Diseases Discovery; Janssen Pharmaceutica NV,

Beerse, Belgium, 3Department of Infectious

Diseases, Molecular Virology; Heidelberg University,

Heidelberg, Germany, 4Cistim Leuven vzw; Center

for Drug Design and Discovery, University of Leuven,

Leuven, Belgium, 5Janssen Discovery Chemistry EU,

Janssen Pharmaceutica NV, Beerse,

Belgium, 6Janssen Discovery Sciences, Janssen-Cilag

Research Center, Val de Reuil, France, 7Janssen

Discovery Sciences, PDM, Janssen Pharmaceutica

NV, Beerse, Belgium, 8Unité des Virus Émergents,

Aix-Marseille Univ–IRD 190–Inserm 1207–IHU

Méditerranée Infection, Marseille, France, 9Aligos

bvba, Leuven, Belgium, 10Janssen Global Public

Health R&D, Janssen Pharmaceutica NV, Beerse,

Belgium

LB-5351

Comprehensive testing of Zika Virus reference

serology panel by Arbovirus Multiplex Assay

Kodumudi S. Venkateswaran, Kavya Rajaram,

Ava Ehrlich, Julian Drabner, William M. Nelson,

Neeraja Venkateswaran

Tetracore Inc., Rockville, MD, United States

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58

Poster Session 131

Poster Session C

Late-Breakers in Basic Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Saturday, November 23, Noon - 1:45 p.m.

Arthropods/Entomology ........................................................#LB-5359 through LB-5372

Kinetoplastida ......................................................................#LB-5373 through LB-5380

Malaria ...............................................................................#LB-5381 through LB-5412

One Health: Interface of Human Health/Animal Diseases ..........#LB-5413 through LB-5419

Viruses ...............................................................................#LB-5420 through LB-5430

LB-5359

Seminal fluid proteins induce transcriptome

changes in theAedes aegyptifemale lower

reproductive tract, including up-regulation of

immunity-related RNAs

I. Alexandra Amaro1, Yasir H. Ahmed-Braimah2,

Frank W. Avila3, Mariana F. Wolfner1, Laura C.

Harrington1 1Cornell University, Ithaca, NY, United

States, 2Syracuse University, Syracuse, NY, United

States, 3Universidad de Antioquia, Medellin,

Colombia

LB-5360

Jamestown Canyon Virus in Michigan

Mosquitoes: 2018-2019

Edward D. Walker

Michigan State University, East Lansing, MI, United

States

LB-5361

Detection and characterization of low level

Wolbachia infections in populations

ofCulicoidesmidges species in the U.S.

Megan L. Matthews, Hunter Hall, Hunter Covey,

Alyssa Krafsur, Corey L. Brelsfoard

Texas Tech University, Lubbock, TX, United States

LB-5362

The abundance and biodiversity of mosquito

species collected in a lowland tropical forest

and associated trap bias

Andrew D. Haddow1, Agricola Odoi2, Boonsong

Jaichapor3, Hilda Guzman4, Jason H. Richardson3,

Robert B. Tesh4, Scott C. Weaver4, Brian P. Evans3,

Alongkot Ponlawat3 1U.S. Army Medical Research Institute of Infectious

Diseases, Frederick, MD, United States, 2University

of Tennessee, Knoxville, TN, United States, 3Armed

Forces Research Institute of Medical Sciences,

Bangkok, Thailand, 4University of Texas Medical

Branch, Galveston, TX, United States

LB-5363

The population distribution and genetic

diversity of autogenous Culex pipiens

molestus in Taipei and Kaohsiung

Kai-Di Yu, Tsai-Ying Yen, Kun-Hsien Tsai

Institute of Environmental and Occupational Health

Sciences, Taipei, Taiwan

LB-5364

Colonization of Aedes aegypti Associated with

Altered Microbiome and Increased Vector

Competence

Christopher M. Roundy1, Divya Mirchandani1,

Maria Pimenova1, Kamil Khanipov1, Georgiy

Golovko1, Yuriy Fofanov1, Grant Hughes2, Scott

Weaver1 1University of Texas Medical Branch, GALVESTON,

TX, United States, 2Liverpool School of Tropical

Medicine, Liverpool, United Kingdom

LB-5365

Densovirus-based microRNA modulation alters

immune gene expression in Anopheles gambiae

Rebecca M. Johnson, Jason L. Rasgon

The Pennsylvania State University, University Park,

PA, United States

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59

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5366

Progenitor cell-mediated midgut repair in

mosquito vectors

Bretta L. Hixson

Cornell University, Ithaca, NY, United States

LB-5367

Assessment of arthropod vector usage from

NIAID’s BEI Resources - supporting vector

control, development, epidemiology and

pathogen transmission research

Timothy T. Stedman, Rebecca Bradford

ATCC, Manassas, VA, United States

LB-5368

Entomological monitoring of malaria vector

control interventions in eleven sentinel sites

across five districts in Malawi

Themba Mzilahowa1, Martin Chiumia1, Atusaye

Simbeye1, Fred Sande1, Veronica Uzalili1, Nixon

Kamanga1, Jomo Banda1, Jules Nahimana2, Miriam

Mokuena3, Xiomara Browne4, Pius Masache4, Jennifer

Burnett2, Jenny Carlson5, John E. Gimnig6, Yemane

Yihdego7, Leonard Dandalo2 1Malaria Alert Centre, College of Medicine, Blantyre,

Malawi, 2US President's Malaria Initiative VectorLonk

Project, Lilongwe, Malawi, 3US President's Malaria

Initiative VectorLonk Project, Rockville, MD, United

States, 4President's Malaria Initiative/ US Agency for

International Development, Lilongwe,

Malawi, 5President's Malaria Initiative/ US Agency for

International Development, Washington DC, WA,

United States, 6Centers for Disease Control and

Prevention, Atlanta, GA, United States, 7US

President's Malaria Initiative VectorLonk Project,

Accra, Ghana

LB-5369

Use of real time and spatial data for Aedes

aegyptimonitoring to improve vector control

response in Jamaica.

Kimalie Fabian Parchment1, Jean Margaritis Otto1,

Quang Troung2, Sherine Huntley Jones3, Dr. Simone

Spence3, Allison Belemvire4 1Abt Associates Inc., Kingston, Jamaica, 2Abt

Associates Inc., Rockville, MD, United

States, 3Ministry of Health and Wellness, Kingston,

Jamaica, 4United States Agency for International

Development, Washingston, DC, United States

LB-5370

Reducing and destroying the Zika virus vector

in Jamaica

Kimalie Parchment1, Sheena Francis1, Kerri-Ann

Guyah1, Jean Margaritis2, Allison Belemvire3, Simone

Spence4, Sherine Huntley-Jones4, Carolina Torres

Gutierrez2 1Abt Associates Jamaica, Kingston, Jamaica, 2Abt

Associates, Rockville, MD, United States, 3United

States, Agency for International Development,

Takoma Park, MD, United States, 4Ministry of Health

and Wellness, Kingston, Jamaica

LB-5371

JNK pathway is antiviral against DENV, ZIKV

and CHIKV in Ae. aegypti salivary glands

Avisha Chowdhury1, Cassandra Modahl1, Siok

Thing Tan1, Benjamin Wong2, R. Manjunatha Kini1,

Julien Pompon3 1National University of Singapore, Singapore,

Singapore, 2Duke-NUS Graduate Medical School,

Singapore, Singapore, 33MIVEGEC, IRD, CNRS, Univ.

Montpellier, Montpellier, France, montpellier, France

LB-5372

An evaluation of characters for the separation

of two Culex species (Diptera: Culicidae) based

on material from the Upper Midwest

Vinicios Ferreira-de-Freitas, Nicholas Thrun,

Lauren Melidosian, Brad Tucker, Susan Paskewitz,

Lyric Bartholomay

University of Wisconsin-Madison, Madison, WI,

United States

LB-5373

An in vitro Model of the Human Placenta to

Study the Mechanisms of Trypanosoma cruzi

Vertical Transmission

Erica Silberstein1, Kwang Sik Kim2, Alain

Debrabant1 1U.S. Food and Drug Administration, Silver Spring,

MD, United States, 2Johns Hopkins Bloomberg School

of Public Health, Baltimore, MD, United States

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60

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5374

High-throughput screening of the ReFRAME

library identifies potential drug repurposing

candidates for Trypanosoma cruzi

Jean A. Bernatchez1, Emily Chen2, Mitchell V. Hull2,

Case W. McNamara2, James H. McKerrow1, Jair L.

Siqueira-Neto1 1University of California, San Diego, La Jolla, CA,

United States, 2California Institute for Biomedical

Research, La Jolla, CA, United States

LB-5375

Growth hormone effect on the in vitro infection

of Trypanosoma cruzi

Patricia Mora-Criollo

Ohio University, athens, OH, United States

LB-5376

Pharmacologic inhibition of

the Leishmania LHR1 heme transporter

Iqbal Hamza1, Maya Shepardson2, Xiaojing Yuan3,

Phillip A. Yates4, Fengtian Xue5 1University of Maryland and Rakta Therapeutics, Inc.,

College Park, MD, United States, 2Rakta

Therapeutics, Inc., College Park, MD, United

States, 3University of Maryland, College Park, MD,

United States, 4Oregon Health & Science University,

Portland, OR, United States, 5University of Maryland

School of Pharmacy, Baltimore, MD, United States

LB-5377

Intrinsic Resistance to Liposomal Amphotericin

B in Leishmania infantum may be due to a

transport-mediated phenomenon sensitive to

inhibitors of ABC transporters

Debjani Mandal, Naomi E. Aronson

Uniformed Services University of Health Science,

Bethesda, MD, United States

LB-5378

Myeloid and lymphoid immune exhaustion

profile during murine visceral leishmaniasis

Diogo Valadares, Breanna Scorza, Erin Cox,

Christine Petersen, Mary Wilson

University of Iowa, Iowa City, IA, United States

LB-5379

Assessing Trypanosoma cruzi diversity through

comparative genomics

Alicia Majeau, Laura Murphy, Claudia Herrera, Eric

Dumonteil

Tulane University, New Orleans, LA, United States

LB-5380

Comparative Evaluation of Conventional,

Quantitative and Droplet Digital PCR for the

Molecular Diagnosis of Chagas Disease

Milli Bijoya Nath-Chowdhury1, Colton Strong2,

Maya Scott-Laurenco2, Eric Chatelain3, Momar Ndao1 1National Reference Center for Parasitology,

Research Institute of the McGill University Health

Center, Montreal, QC, Canada, 2McGill University,

Department of Microbiology and Immunology,

Montreal, QC, Canada, 3Drugs for Neglected Diseases

initiative, Geneva, Switzerland

LB-5381

Bloodmeal analysis of wild-caught Anopheles

stephensi in Ethiopia

Joseph Daniel Spear1, Sae Hee Choi1, Solomon

Yared2, Meshesha Balkew3, Peter Mumba3, Dereje

Dengela4, Gedeon Yohannes3, Dejene Getachew5,

Sheleme Chibsa6, Matthew Murphy7, Kristen George8,

Cecilia Flately9, Karen Lopez10, Daniel Janies10, Seth

R. Irish11, Tamar E. Carter1 1Baylor University, Waco, TX, United States, 2Jigjiga

University, Jigjiga, Ethiopia, 3PMI VectorLink Ethiopia

Project, Addis Ababa, Ethiopia, 4PMI VectorLink

Project, Rockville, MD, United States, 5Dire Dawa

University, Dire Dawa, Ethiopia, 6U.S President’s

Malaria Initiative (PMI) program, Addis Ababa,

Ethiopia, 7U.S. President's Malaria Initiative and

Malaria Branch, Division of Parasitic Diseases and

Malaria, Centers for Global Health, Centers of

Disease Control and Prevention, Atlanta, GA, United

States, 8USAID| Bureau for Global Health | Office of

Infectious Disease, Arlington, VA, United States, 9Abt

Associates, PMI VectorLink Project, Rockville, MD,

United States, 10University of North Carolina at

Charlotte, Charlotte, NC, United States, 11U.S.

President’s Malaria Initiative and Entomology Branch,

Centers for Disease Control and Prevention, Atlanta,

GA, United States

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61

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5382

Structural ordering of the PbCSP repeat by

malaria inhibitory antibody 3D11

Iga Kucharska1, Elaine Thai1, Ananya Srivastava1,

Stephen Scally2, John Rubinstein1, Régis Pomès1,

Jean-Philippe Julien1 1The Hospital for Sick Children Research Institute,

Toronto, ON, Canada, 2Walter and Eliza Hall Institute

of Medical Research, Parkville, Australia

LB-5383

Increased production of Pfs230D1M by over-

expression of Pichia pastoris protein disulfide

isomerase

Deepika Seethamraju, Vu Nguyen, Karine Reiter,

Raul Herrera, Patrick E. Duffy, Nicholas J.

MacDonald, David L. Narum

LMIV, NIAID/NIH, Bethesda, MD, United States

LB-5384

Characterization of the protective immune

responses elicited by Plasmodium vivax Duffy

binding protein, DBP II in mice

Sai Lata De, Samuel May, Keshav Shah, Michelle

Swalinski, Francis Ntumngia, John Adams

University of South Florida, TAMPA, FL, United States

LB-5385

Pre-clinical evaluation of Transmission Blocking

Candidates Pvs230D1M-EPA and Pvs25M-EPA

in small animal models

Kelly M. Rausch, Lynn E. Lambert, Emma K.

Barnafo, Karine Reiter, Nada Alani, Albert Jin, Sachy

Orr-Gonzalez, Tarik Ouahes, Emily R. Higbee, Olga

Muratova, Charles Anderson, David L. Narum, Patrick

E. Duffy

LMIV, NIAID/NIH, Bethesda, MD, United States

LB-5386

Mechanisms of red blood cell clearance during

post-artemisinin hemolysis: a proteomic

approach

Charlotte Chambrion1, Aida Taieb2, Emilie-Fleur

Gautier3, Oussama Mouri4, Michael Dussiot5, Eric

Kendjo4, Aurélie Fricot-Monsinjon6, Mallorie Depond7,

Camille Roussel1, Nicolas Argy8, Sandrine Houze8,

Patrick Mayeux3, Jean-Yves Siriez9, Sébastien

Larréché10, Marc Thellier4, Pierre Buffet1, Papa

Alioune Ndour1 1Institut National de la transfusion Sanguine, Unité

1134, Centre National de Référence du paludisme,

Université de Paris, Laboratoire d'Excellence GREX,

Paris, France, 2Centre National de Référence du

paludisme, Paris, France, 3Institut Cochin, U1016,

Université de Paris, Laboratoire d'Excellence GREX,

Paris, France, 4Centre National de Référence du

paludisme, Hôpital Pitié Salpêtrière, Paris,

France, 5Université de Paris, Laboratoire d'Excellence

GREX, Paris, France, 6Institut National de la

transfusion Sanguine, Unité 1134,Université de Paris,

Laboratoire d'Excellence GREX, Paris,

France, 7Institut National de la transfusion Sanguine,

Unité 1134, Université de Paris, Laboratoire

d'Excellence GREX, Paris, France, 8Centre National de

Référence du paludisme, Hôpital Xavier Bichat-

Claude Bernard, Paris, France, 9Hôpital Robert

Debré, Paris, France, 10Hôpital d'Instruction des

Armées Begin, Paris, France

LB-5387

Strengthening individual malaria surveillance,

monitoring, and evaluation capacity in Nigeria

Ibrahim K. Maikore1, Ashley Garley2, Cyril Ademu1,

Uwem Inyang3, Mark Maire4, Perpetua Uhomoibhi1,

Yazoume Ye2, Festus O. Okoh1 1National Malaria Elimination Program, Abuja,

Nigeria, 2USAID-funded MEASURE Evaluation,

University of North Carolina at Chapel Hill and ICF,

Washington DC, WA, United States, 3USAID

President’s Malaria Initiative, Abuja, Nigeria, 4CDC

President’s Malaria Initiative Nigeria, Abuja, Nigeria

LB-5388

Production of the recombinant full-

length Plasmodium vivax48/45 gametocyte

protein and its biophysical characterization

Andrey V. Kajava1, Sebastien Deshayes1, Jeremy

Leclercq1, Giampietro Corradin2, Socrates Herrera3,

Myriam Arevalo-Herrera3 1Centre National de la Recherche Scientifique,

Montpellier, France, 2Department of Biochemistry,

University of Lausanne, Lausanne,

Switzerland, 3Caucaseco Scientific Research Center,

Cali, Colombia

LB-5389

TREM-1 in the inflammatory response and

progression to severe malaria

Michelle Ngai1, Laura K. Erdman2, Kathleen Zhong1,

Melissa Richard-Greenblatt1, Kevin C. Kain1 1University Health Network, Toronto, ON,

Canada, 2Hospital for Sick Children, Toronto, ON,

Canada

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62

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5390

Background matters: effect on ring stage

survival by specific Kelch13 mutations depends

on their genome wide genetic context

Lisa A. Checkley Needham1, Douglas A. Shoue1,

Puspendra P. Singh1, Zione Cassady1, Mackenzie A.

Sievert1, Shalini K. Nair2, Timothy J. Anderson2,

François H. Nosten3, Michael T. Ferdig1 1University of Notre Dame, Notre Dame, IN, United

States, 2Texas Biomedical Research Institute, San

Antonio, TX, United States, 3Shoklo Malaria

Reasearch Unit, Mahidol Oxford Tropical Medicine

Research Unit, Mahidol University, Mae Sot, Thailand

LB-5391

Extended Recovery Ring stage Survival Assay-

a modified RSA that better predicts parasite

clearance half-life

Puspendra P. Singh1, Sage Z. Davis2, Douglas A.

Shoue1, Lisa A. Checkley1, Zione L. Cassady1,

Mackenzie AC Sievert1, Timothy JC Anderson3,

François H. Nosten4, Michael T. Ferdig1 1Eck Institute for Global Health, Department of

Biological Sciences, University of Notre Dame, Notre

Dame, IN, United States, 2Molecular, Cell, and

Systems Biology Department, University of California

Riverside, Riverside, CA, United States, 3Texas

Biomedical Research Institute, San Antonio, TX,

United States, 4Shoklo Malaria Research Unit,

Mahidol Oxford Tropical Medicine Research Unit,

Mahidol University, Maie Sot, Thailand

LB-5392

Targeting host kinases to protect the

endothelial barrier from hyper-inflammatory

damage

Selasi Dankwa, Mary-Margaret Dols, Ling Wei,

Elizabeth K. Glennon, Heather Kain, Alexis

Kaushansky, Joseph D. Smith

Seattle Children's Research Institute, Seattle, WA,

United States

LB-5393

Integration of Hydrologic Modeling with

Remote Sensing Data to Predict Distribution of

Malaria Vector Larval Habitats in Ethiopia

Ming-Chieh Lee, Ai-Ling Jiang, Kuolin Hsu, Guiyun

Yan

University of California, Irvine, Irvine, CA, United

States

LB-5394

Effects of cost on care seeking among febrile

under five children in Malawi

Collins Jack Kwizombe1, Austin A. Gumbo2, Monica

Bautista1, Michael Kayange2 1PMI-USAID, Lilongwe, Malawi, 2Ministry of Health

(National Malaria Control Programme), Lilongwe,

Malawi

LB-5395

Genomic insights into Plasmodium

vivax transmission dynamics, the impact of

control efforts and sources of rebound

Abebe A. Fola1, Eline Kattenberg2, Zahra Razook3,

Raksmei Keo3, Cristian Koepfli4, Dulcie Lautu3, Stuart

Lee3, Somya Mehra3, Melanie Bahlo3, Manuel Hetzel5,

Ivo Mueller3, Alyssa E. Barry6 1Department of Biological Sciences, Purdue

University, West Lafayette, IN, United

States, 2Institute of Tropical Medicine, Antwerp,

Belgium, 3Walter and Eliza Hall Institute of Medical

Research, Melbourne, Australia, 4Eck Institute for

Global Health, University of Notre Dame, Notre

Dame, IN, United States, 5University of Basel, Basel,

Switzerland, 6School of Medicine, Deakin University,

Geelong, Australia

LB-5396

Robust 6 SNP Assays for Genotyping P.

falciparum Infections

Sarah McNitt1, Chi-Yun Wu2, Dylan Small2, Jimmy

Vareta3, Karl Seydel1 1Michigan State University, East lansing, MI, United

States, 2University of Pennsylvania, Philadelphia, PA,

United States, 3University of Maryland School of

Medicine, Baltimore, MD, United States

LB-5397

The effect of sickle trait on P.

falciparum var gene transcription and infected

erythrocyte adhesion.

Jens E.V. Petersen1, Joseph W. Saelens1, Betsy

Freedman1, Thomas Lavstsen2, Steve M. Taylor1 1Duke University, DURHAM, NC, United

States, 2University of Copenhagen, Copenhagen,

Denmark

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63

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5398

Testing the protective efficacy of two late liver

stage-arresting Genetically Attenuated rodent

malaria Parasites in thicket rats and mice

Solomon Conteh1, Jacqueline Kolasny1, Lynn E.

Lambert1, Ashley Vaughn2, Stefan Kappe2, Patrick E.

Duffy1 1LMIV, NIAID/NIH, Bethesda, MD, United

States, 2Center for Global Infectious Disease

Research, Seattle Children's Research Institute,

Seattle, WA, United States

LB-5399

Kb-17 peptide derived from Plasmodium

berghei liver stage antigen induces CD8 T cells

with MHCI-restricted cytolytic activity

Nouf Althubaiti

WRAIR, silver spring, MD, United States

LB-5400

An exogenously expressed Plasmodium

falciparum ligand significantly improved

Plasmodium knowlesi ability to invade human

erythrocytes

Kwame K. Asare1, Amuza B. Lucky1, Miho Kaneko2,

Phonepadith Xangsayarath3, Yuko Katakai4, Satoru

Kawai5, Kazuhide Yahata3, John H. Adams6, Osamu

Kaneko1 1Department of Protozoology, Institute of Tropical

Medicine (NEKKEN) and Leading Program, Graduate

School of Biomedical Sciences, Nagasaki University,

Nagasaki, Japan, 2Department of Protozoology,

Institute of Tropical Medicine (NEKKEN) and

Graduate School of Biomedical Sciences, Nagasaki

University, Nagasaki, Japan, 3Department of

Protozoology, Institute of Tropical Medicine

(NEKKEN), Nagasaki University, Nagasaki,

Japan, 4The Corporation for Production and Research

of Laboratory Primates, Tsukuba,

Japan, 5Department of Tropical Medicine and

Parasitology, Dokkyo Medical University, Mibu-machi,

Japan, 6Center for Global Health and Infectious

Diseases Research, College of Public Health,

University of South Florida, Tampa, FL, United States

LB-5401

Vd6.3 gamma delta T cells are essential to

induce sterile immunity in a mouse model of

whole organism vaccination

against Plasmodium

Irfan Zaidi, Solomon Conteh, Brandi Butler, Javonn

Musgrove, Lynn E. Lambert, Patrick E. Duffy

LMIV, NIAID/NIH, Bethesda, MD, United States

LB-5402

Antigenicity and functional epitope mapping of

Plasmodium vivax Pvs48/45 protein

Eduardo Solano1, Nora Cespedes2, Carlos

Echeverry2, Angela Valencia2, Daniela Gutierrez1,

Michelle Pardo2, Juan S. Ramirez2, Giampietro

Corradin3, Socrates Herrera1, Myriam Arevalo-

Herrera2 1Caucaseco Research Center, Cali, Colombia, 2Malaria

Vaccine and Drug Development Center, Cali,

Colombia, 3Department of Biochemistry, University of

Lausanne, Lausanne, Switzerland

LB-5403

Vector competence of SkitoSnack-raised Aedes

aegypti and Anopheles

stephensi for Plasmodium gallinaceum and P.

falciparum.

Kristina Kay Gonzales-Wartz, Juliana M. Sa, Kevin

Lee, Yonas Gebremicale, Andre Laughinghouse,

Samuel E. Moretz, Ana M. Ortega-Villa, Michael P.

Fay, Thomas E. Wellems

National Institutes of Health, Rockville, MD, United

States

LB-5404

Evaluating a placental malaria vaccine

candidate in the Aotus nancymaae model of

Placental Malaria

Holly M. Torano1, Justin Doritchamou1, Lynn

Lambert1, Ankur Sharma1, Jonathan P. Renn1, Alicia

Spiegel1, Matthew Cowles1, Steven Nadakal1,

Maryonne Snow-Smith1, Tarik Ouahes1, Emma

Barnafo1, Nicola Viebig2, Robert Morrison1, Joseph

Shiloach3, David Narum1, Michal Fried1, Patrick E. E.

Duffy1 1NIH/NIAID/LMIV, Bethesda, MD, United

States, 2European Vaccine Initiative (EVI),

Heidelberg, Germany, 3NIH/NIDDK/ Biotechnology

Core, Bethesda, MD, United States

LB-5405

Immune response in mice after Plasmodium

yoelii infection and its association with

bacteremia and mast cell activation

Nora Cespedes1, Erinn Donnelly1, Lori Haapanen2,

Judy Van De Water2, Shirley Luckhart1 1University of Idaho, Moscow, ID, United

States, 2University of California, Davis, CA, United

States

Page 65: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

64

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5406

Estimating the impact of spatial repellents and

odour baited traps on malaria transmission

from semi-field experiments

Adrian E. Denz1, Margaret Mendi Njoroge2, Mgeni

Mohamed3, Sarah Moore1, Fredros Okumu3, Ulrike

Fillinger2, Alexandra Hiscox4, Adam Saddler1, Nakul

Chitnis1 1Swiss Tropical and Public Health Institute, Basel,

Switzerland, 2International Centre of Insect

Physiology and Ecology, Mbita, Kenya, 3Ifakara

Health Institute, Ifakara, Tanzania, United Republic

of, 4ARCTEC, LSHTM, London, United Kingdom

LB-5407

Varied sensitivities to PfATP4 inhibitors and

associations with genotypes in Ugandan P.

falciparum isolates

Oriana K. Kreutzfeld1, Stephanie A. Rasmussen2,

Patrick K. Tumwebaze3, Oswald Byaruhanga3,

Thomas Katairo3, Martin Okitwi3, Stephen Orena3,

Jennifer Legac1, Melissa Conrad1, Samuel Nsobya3,

Ozkan Aydemir4, Jeff Bailey4, Maelle Duffey5, Brett

Bayles2, Roland A. Cooper2, Philip J. Rosenthal1 1UCSF, San Francisco, CA, United States, 2Dominican

University of California, San Rafael, CA, United

States, 3Infectious Diseases Research Collaboration,

Kampala, Uganda, 4Brown University, Providence, RI,

United States, 5Medicines for Malaria Venture,

Geneva, Switzerland

LB-5408

Sensitive, highly multiplexed sequencing of

Plasmodium falciparum microhaplotypes

Sofonias K Tessema1, Nicholas J. Hathaway2,

Noam Teyssier1, Anna Chen1, Elias M. Duarte1, Ozkan

Aydemir3, James Colborn4, Baltazar Candrinho5,

Francisco Saute6, Francisco Saute6, Pedro Aide6,

Jeffrey A. Bailey3, Bryan Greenhouse1 1EPPIcenter, Department of Medicine, University of

California, San Francisco, San Francisco, CA, United

States, 2Program in Bioinformatics and Integrative

Biology, University of Massachusetts, Worcester, MA,

United States, 3Department of Pathology and

Laboratory Medicine, Warren Alpert Medical School,

Brown University, Providence, RI, United

States, 4Clinton Health Access Initiative, Maputo,

Mozambique, 5National Malaria Control Program,

Ministry of Health, Maputo, Mozambique, 6Centro de

Investigação em Saúde de Manhiça (CISM), Manhiça,

Mozambique

LB-5409

Structure-function characterization of PfCSP-

targeted monoclonal antibody 5D5 to guide

malaria vaccine design

Elaine Thai1, Giulia Costa2, Anna Weyrich3,

Rajagopal Murugan4, Alexandre Bosch1, Katherine

Prieto1, Stephen Scally1, Hedda Wardemann4, Elena

Levashina3, Jean-Philippe Julien1 1Hospital for Sick Children, Toronto, ON,

Canada, 2Max Planck Institute for Infection Biology,

Germany, Berlin, Germany, 3Max Planck Institute for

Infection Biology, Berlin, Germany, 4German Cancer

Research Center, Heidelberg, Germany

LB-5410

Potent antibody lineage against malaria

transmission elicited by human vaccination

with Pfs25

Brandon Robert McLeod1, Kazutoyo Miura2,

Stephen W. Scally1, Alexandre Bosch1, Ngan

Nguyen3, Hanjun Shin3, Dongkyoon Kim3, Wayne

Volkmuth3, Sebastian Rämisch4, Jessica A.

Chichester5, Stephen Streatfield6, Colleen Woods7,

William R. Schief4, Daniel Emerling3, C. Richter King7,

Jean-Philippe Julien1 1The Hospital for Sick Children, Toronto, ON,

Canada, 2Laboratory of Malaria and Vector Research,

National Institute of Allergy and Infectious Diseases,

National Institutes of Health, Rockville, MD, United

States, 3Atreca, Redwood City, CA, United

States, 4The Scripps Research Institute, La Jolla, CA,

United States, 5The University of Pennsylvania,

Philadelphia, PA, United States, 6Fraunhofer USA

Center for Molecular Biotechnology, Newark, DE,

United States, 7PATH’s Malaria Vaccine Initiative,

Washington, DC, United States

LB-5411

Transcriptional analysis

of Plasmodium parasite-host cell interaction in

the CD68 KO mouse liver for characterization of

hepatic immune modulation that inhibits

experimental cerebral malaria development

YONGSEOK LEE

Johns Hopkins Bloomberg School of Public Health,

ELLICOTT CITY, MD, United States

Page 66: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

65

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5412

Cas-9 mediated gene-editing in the malaria

mosquito Anopheles stephensi by ReMOT

Control

Vanessa Macias1, Sage McKeand1, Duverney

Chaverra-Rodrigues1, Grant L. Hughes2, Aniko

Fazekas3, Nijole Jasinskiene3, Anthony A. James3,

Jason L. Rasgon1 1Penn State University, State College, PA, United

States, 2Liverpool School of Tropical Medicine,

Liverpool, United Kingdom, 3University of California,

Irvine, CA, United States

LB-5413

Monitoring species composition of Ixodidae

ticks in tularemia foci in the Shirak region of

Armenia

Ruben Danielyan, Levon Sahakyan

National Center for Disease Control and Prevention,

Yerevan, Armenia

LB-5414

The impact of climate warming on the malaria

receptivity of Armenia

Ara Keshishyan1, Gajane Melik-Andreasyan1,

Hamlet Melkonyan2 1National Center for Disease Control and Prevention,

Yerevan, Armenia, 2Service of the Ministry of

Emergency Situations, Yerevan, Armenia

LB-5415

Emergence of Lyme borreliosis in the Republic

of Armenia

Lusine Paronyan, Laura Mkrtchyan, Karine

Gevorgyan, Rita Jhangiryan, Vardine Mehrabyan, Lilit

Avetisyan, Artavazd Vanyan

National Center for Disease Control and Prevention,

Yerevan, Armenia

LB-5416

Evaluation of Salmonellosis occurrences in

domestic animals and animal source foods in

Azerbaijan for the period of 2013-2017

Fidan Ahmadova1, Tamilla Aliyeva2, Khalid

Bayramli2, Aytan Haciyeva3 1National Reference Laboratory, Baku,

Azerbaijan, 2Food Safety Institute of the Republic of

Azerbaijan, Baku, Azerbaijan, 3Central Veterinary

Laboratory, Baku, Azerbaijan

LB-5417

Trends and Characteristics of Published Studies

on Infectious Disease with Data Integration

and Linkage from 2009 to 2018

Daniel Rhee1, Seul-gi Kim2, Kyung-Duk Min3,

Sangwoo Tak2 1Seoul National University College of Medicine, Seoul,

Korea, Republic of, 2Seoul National University

Graduate School of Public Health, Seoul, Korea,

Republic of, 3Seoul National University Institute of

Health and Environment, Seoul, Korea, Republic of

LB-5418

The epidemiological severity of recent

Kyasanur Forest Disease outbreak in an

unexpected Western Ghat region of

Southwestern India suggests increased

invasiveness

Rajeshwara Achur1, Sayad Hafeez2, N.B

Thippeswamy2 1Dept. of Biochemistry, Kuvempu University,

Shivamogga, India, 2Dept. of Microbiology, Kuvempu

University, Shivamogga, India

LB-5419

CHLAMYDIA CIRCULATION IN FARM ANIMALS

FROM NORTHEASTERN ARGENTINA

Ezequiel Vanderhoeven1, Cecilia Cuffini2, Adrian

Diaz2 1Instituto Nacional de Medicina Tropical, Secretaria

de Salud, Ministerio de Salud y Desarrollo Social,

Argentina, Puerto Iguazu, Argentina, 2Instituto de

Virología "Dr. J. M. Vanella" - Facultad de Ciencias

Médicas, Universidad Nacional de Cordoba, Córdoba,

Argentina

LB-5420

Rapid Generation of High-Affinity Zika-

Neutralizing Single-Chain Antibodies by

Ribosome Display

Adinarayana Kunamneni1, Chunyan Ye2, Steven

Bradfute2, Ravi Durvasula1 1Loyola University Chicago, Maywood, IL, United

States, 2University of New Mexico, Albuquerque, NM,

United States

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66

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5421

Performance of the TaqMan Array Card for

dengue, Zika and chikungunya detection in

acute febrile illness in Latin America

Angelica Espinoza1, Carolina Guevara2, Julia S.

Ampuero2, Fields Barry3, Jie Liu4, Jenkins

Sarah2, Maria Elizabeth Silva2 1U.S Naval Medical Reserach Unit - 6, Lima,

Peru, 2Naval Medical Research Unit - 6, Lima,

Peru, 3Centers for Disease Control & Prevention,

Atlanta, GA, United States, 4University of Virginia,

Virginia, VA, United States

LB-5422

Increased transmissibility of emergent

genotypes of West Nile virus

Sean M. Bialosuknia, Kiet A. Ngo, Joseph G. Maffei,

Jessica Stout, Laura D. Kramer, Alexander T. Ciota

Wadswoth Center, NYS Dept of Health, Slingerlands,

NY, United States

LB-5423

Potent Zika and dengue cross-neutralizing

antibodies induced by Zika vaccination in a

dengue-exposed donor

Vincent Dussupt1, Rajeshwer S. Sankhala1,

Gregory D. Gromowski2, Gina Donofrio1, Rafael A. De

La Barrera3, Rafael A. Larocca4, Weam Zaky1,

Letzibeth Mendez-Rivera1, Misook Choe1, Edgar

Davidson5, James D. Brien6, Peter Abbink4, Amelia

Pinto6, Wiriya Rutvisuttinunt2, Benjamin J. Doranz5,

Kenneth H. Eckels3, Elizabeth Barranco7, Darci R.

Smith8, Richard G. Jarman2, Michael Koren2, Sarah L.

George6, Kathryn E. Stephenson4, Dan H. Barouch4,

Kayvon Modjarrad9, Nelson L. Michael10, M. Gordon

Joyce1, Shelly J. Krebs1 1U.S. Military HIV Research Program, Walter Reed

Army Institute of Research. Henry M. Jackson

Foundation for the Advancement of Military Medicine,

Silver Spring, MD, United States, 2Viral Diseases

Branch, Walter Reed Army Institute of Research,

Silver Spring, MD, United States, 3Pilot Bioproduction

Facility, Walter Reed Army Institute of Research,

Silver Spring, MD, United States, 4Center for Virology

and Vaccine Research, Beth Israel Deaconess Medical

Center, Harvard Medical School, Boston, MA, United

States, 5Integral Molecular, Philadelphia, PA, United

States, 6Department of Internal Medicine, Division of

Infectious Diseases, Allergy and Immunology, Saint

Louis University School of Medicine, Saint Louis, MO,

United States, 7Ponce Health Sciences University,

CAIMED Center, Ponce, PR, United States, 8U.S.

Army Medical Research Institute of Infectious

Diseases, Fort Detrick, MD, United States, 9Emerging

Infectious Diseases Branch, Walter Reed Army

Institute of Research, Silver Spring, MD, United

States, 10U.S. Military HIV Research Program, Walter

Reed Army Institute of Research, Silver Spring, MD,

United States

LB-5424

The distribution and prevalence of Powassan

virus in New York State

Alan P. Dupuis

New York State Department of Health - Wadsworth

Center, Slingerlands, NY, United States

LB-5425

Development of a Cross-Protective Multivalent

Vaccine for Tick-Borne Flaviviruses

David Clements1, Jaime Horton1, Gloria Corpuz1,

Robbin Henley1, James Senda1, Timothy Martyak1,

Terry Juelich2, Birte Kalveram2, Jennifer Smith2,

Lihong Zhang2, Alan Barret2, Alexander Freiberg2 1Hawaii Biotech, HONOLULU, HI, United

States, 2University of Texas Medical Branch,

Galveston, GALVESTON, TX, United States

LB-5426

Safety and Immunogenicity of a Recombinant

Rift Valley fever virus Vaccine Candidate

Containing a Modified Two-Segment Genome

Victoria B. Ayers1, Yan-Jang S. Huang1, Ashley N.

Doerfler1, Amy C. Lyons1, Christian L. Young1, James

I. Dunlop2, Alain Kohl2, Stephen Higgs1, Dana L.

Vanlandingham1 1Department of Diagnostic Medicine/Pathobiology,

College of Veterinary Medicine, Kansas State

University, Biosecurity Research Institute,

Manhattan, KS, United States, 2MRC-University of

Glasgow Centre for Virus Research, Glasgow G61

1QH, United Kingdom

LB-5427

Novel flaviviruses discovered among South

American mosquitoes

Nicholas Komar1, Zika Virus Ecology Study Team2 1Centers for Disease Control and Prevention, Fort

Collins, CO, United States

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67

Poster Session C

Late-Breakers in Basic Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5428

Detection of non-coding subgenomic flavivirus

RNA (sfRNA) from Asian lineage Zika virus in

three species of Ugandan bats (family

Pteropodidae)

Anna C. Fagre, Juliette Dean, Megan R. Miller, John

Anderson, Rebekah C. Kading

Colorado State University, Fort Collins, CO, United

States

LB-5429

First reported outbreak of Chikungunya virus in

a town in the northern highlands of Peru

Wilmer G. Silva-Caso1, Juana M. del Valle-

Mendoza1, Carlos C. Palomares-Reyes1, Miguel A.

Aguilar-Luis1, Daniel Cornejo-Pacherres2, Victor

Zavaleta-Gavidia2, Jorge Bazán-Mayra2, Homero

Bazán-Zurita3, Luis J. Del Valle4 1Universidad Peruana de Ciencias Aplicadas, Lima,

Peru, 2Dirección Regional de Salud de Cajamarca,

Cajamarca, Peru, 3Universidad Privada Antonio

Guillermo Urrelo, Cajamarca, Peru, 4Universidad

Politecnica de Catalunya (UPC), Barcelona, Spain

LB-5430

Classic Dengue serotypes not identified in

DENV positive samples and identification of

other pathogens present duringthe 2016

outbreak

Juana M. del Valle1, Fernando Vasquez-Achaya1,

Wilmer Silva-Caso1, Luis J. del Valle2, Jorge Bazán-

Mayra3, Victor Zavaleta-Gavidia4, Daniel Cornejo-

Pacherres3, Carlos Palomares-Reyes1, Johanna

Martins-Luna1, Homero Bazán-Zurita5, Miguel Angel

Aguilar-Luis1 1Universidad Peruana de Ciencias Aplicadas, Lima,

Peru, 2Universidad Politecnica de Catalunya (UPC),

Barcelona, Spain, 3Laboratorio de Referencia.

Dirección Regional de Salud de Cajamarca,

Cajamarca, Peru, 4Dirección Regional de Salud de

Cajamarca, Cajamarca, Peru, 5Universidad Privada

Antonio Guillermo Urrelo, Cajamarca, Peru

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68

Poster Session 131

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Prince George's Exhibit Hall D (Lower Atrium Level)

Saturday, November 23, Noon - 1:45 p.m.

Arthropods/Entomology ........................................................#LB-5431 through LB-5441

Global Health .......................................................................#LB-5442 through LB-5465

HIV and Tropical Co-Infections ...............................................#LB-5466 through LB-5469

Malaria ...............................................................................#LB-5470 through LB-5507

Protozoa .............................................................................#LB-5508 through LB-5513

Viruses ...............................................................................#LB-5514 through LB-5527

Water, Sanitation, Hygiene and Environmental Health ..............#LB-5528 through LB-5535

LB-5431

Performance of the InBios

Babesiosis DetectTM ELISA (RUO) for diagnosis

of Babesia microti infection

Aarthy C. Vallur1, Dindo Reyes1, Masa Okamato1,

Laura Tonnetti2, James Needham1, Gregory Ireton1,

Syamal Raychaudhuri1, Raymond Houghton1 1InBios International inc, Seattle, WA, United

States, 2American Red Cross Holland Laboratory,

Rockville, MD, United States

LB-5432

Analysis of IgG responses to the 34k2 salivary

proteins from Aedes albopictus and Aedes

aegypti in a murine model

Sara Buezo Montero1, Paolo Gabrieli2, Francesco

Severini3, Leonardo Picci3, Marco Di Luca3, Federico

Forneris2, Luca Facchinelli4, Marta Ponzi3, Fabrizio

Lombardo1, Bruno Arca1 1Sapienza University of Rome, Rome,

Italy, 2University of Pavia, Pavia, Italy, 3Istituto

Superiore di Sanità, Rome, Italy, 4Liverpool School of

Tropical Medicine, Liverpool, United Kingdom

LB-5433

Development of a Portable Real Time PCR

Method for Detection of Zika and Dengue

in Aedes Mosquitoes

Natalie Rutkowski, Yuemei Dong, George

Dimopoulos

Johns Hopkins Bloomberg School of Public Health,

Baltimore, MD, United States

LB-5434

CRISPR-Cas13a mediated RNA interference for

gene silencing in mosquitoes

Aditi Kulkarni, Wanqin Yu, Jiannong Xu

New Mexico State University, Las Cruces, NM, United

States

LB-5435

A Systematic Review of Treatment Strategies

for Percutaneously Introduced Marine Toxins

and Venoms

Leila Makhani1, Ruwandi Kariyawasam2, Aisha

Khatib1, Rachel Lau3, Swana Kopalakrishnan1, Mofe

Adeosun1, Shareese Clarke1, Andrea K. Boggild4 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Institute of Medical Sciences,

University of Toronto, Toronto, ON, Canada, 3Public

Health Ontario Laboratories, Toronto, ON,

Canada, 4Tropical Disease Unit, Toronto General

Hospital, University of Toronto, Toronto, ON, Canada

LB-5436

A Systematic Review of Treatment Strategies

for Ingested Marine Toxins

Aisha Khatib1, Ruwandi Kariyawasam2, Leila

Makhani1, Rachel Lau3, Farah Jazuli4, Shveta

Bhasker1, Eric Shao1, David Harris1, Andrea K.

Boggild5 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Institute of Medical Sciences,

University of Toronto, Toronto, ON, Canada, 3Public

Health Ontario Laboratories, Toronto, ON,

Canada, 4Department of Emergency Medicine,

McMaster University, Hamilton, ON,

Canada, 5Tropical Disease Unit, Toronto General

Hospital, and University of Toronto, Toronto, ON,

Canada

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69

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5437

Prevalence of Two Bacterial Pathogens in Fleas

and Tissues from Free Roaming Domestic Cats

Charlotte O. Manvell, Erin Lashnits, Hanna

Berman, Kelli Ferris, Ben Callahan, Edward

Breitschwerdt

North Carolina State University, Raleigh, NC, United

States

LB-5438

Combatting Arboviruses Vectors,Transmission

Risks, Insecticide Resistance and control

perspectives of Aedes aegypti populations of

Burkina Faso

Kounbobr Roch Dabire

Institut de Recherche en Sciences de la Santé, Bobo-

Dioulasso, Burkina Faso

LB-5439

Relapsing Fever Borreliosis in a Patient

Returning from Mexico

Bobbi S. Pritt1, David A. Grunst1, Lynne M. Sloan1,

Matthew J. Wolf1, Emily C. Fernolz1, Joseph Kent2,

Roland Marshall2 1Mayo Clinic, Rochester, MN, United States, 2Christ

Hospital, Oak Lawn, IL, United States

LB-5440

Glycolysis and Blood-Meal Enhanced Immunity

of Anopheles gambiae Mosquitoes

Alex S. Moon, Aditi Kulkarni, Jiannong Xu

New Mexico State University, Las Cruces, NM, United

States

LB-5441

A tool for image classification of Anopheles

gambiae and Anopheles funestus in the field

Tristan Ford, Adam Goodwin, Sanket

Padmanabhan, Margaret Glancey, Sanchit Hira,

Soumyadipta Acharya

Johns Hopkins University, Baltimore, MD, United

States

LB-5442

A novel entomological capacity building

program in the SADC Malaria Elimination Eight

countries: Meeting programmatic needs and

early lessons from a review of the program

Chadwick Sikaala, Lesley Anne van Wyk, Nyasha

Mwendera, Immo Kleinschmidt

SADC Malaria Elimination 8, Windhoek, Namibia

LB-5443

Piloting of an Entomological Surveillance

Planning Tool to Improve Entomological

Intelligence for Evidence-based Vector Control

Decision-making Towards Malaria Elimination

Elodie A. Vajda1, Allison Tatarsky1, Neil F. Lobo2 1University of Califonia, San Francisco, San

Francisco, CA, United States, 2University of Notre

Dame, Notre Dame, IN, United States

LB-5444

Seroprevalence of Ebola GP antibodies by

community, healthcare and zoonotic exposures

in the Democratic Republic of Congo (DRC)

Anna Bratcher1, Nicole A. Hoff1, Reena H. Doshi1,

Adva Gadoth1, Patrick Mukadi2, Kamy Musene3,

Benoit Ilunga-Kebela4, D'Andre Spencer1, Matthew

Bramble5, David McIlwan6, J. Daniel Kelly7, Daniel

Mukadi2, Steve Ahuka2, Emile Okitolonda-Wemakoy3,

Jean-Jacques Muyembe-Tamfum2, Anne W. Rimoin1 1UCLA Fielding School of Public Health, Los Angeles,

CA, United States, 2Institut National de Recherche

Biomedicale, Kinshasa, Democratic Republic of the

Congo, 3Kinshasa School of Public Health, Kinshasa,

Democratic Republic of the Congo, 4Direction de lutte

contre la maladie-Ministère de la santé Publique,

Kinshasa, Democratic Republic of the Congo, 5Center

for Genetic Medicine Research, Children’s National

Medical Center, Washington, DC, United

States, 6Department of Microbiology and

Immunology, Stanford University, Stanford, CA,

United States, 7School of Medicine, University of

California, San Francisco, San Francisco, CA, United

States

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70

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5445

Unmet needs associated with fewer referrals to

treatment and safe burials during the Ebola

response in Sierra Leone

Laura Skrip1, Jamie Bedson2, Sharon Abramowitz3,

Mohammed B. Jalloh4, Saiku M. Bah2, Mohamed F.

Jalloh4, Ollin Demian Langle Chimal5, Nicholas

Cheney5, Laurent Hébert-Dufresne5, Benjamin M.

Althouse1 1Institute for Disease Modeling, Bellevue, WA, United

States, 2Restless Development Sierra Leone,

Freetown, Sierra Leone, 3Consultant, Boston, MA,

United States, 4FOCUS 1000, Freetown, Sierra

Leone, 5Vermont Complex Systems Center,

Department of Computer Science, University of

Vermont, Burlington, VT, United States

LB-5446

A systematic review of publication

characteristics and results from an electronic

survey on research related to human

schistosomiasis and soil-transmitted helminth

transmission and control

Cristin Alexis Fergus, Georgina Pearson

London School of Economics and Political Science,

London, United Kingdom

LB-5447

New Ruggedized Mobile Labs Improve

Outbreak Readiness & Response in Challenging

Environments

Julius Lutwama1, Mark Kortepeter2, John Dye3,

Cathy Bansbach4, Andrew Herbert3, Calum Semple5,

Kartik Chandran6, David Franz7, Keyur Patel8, Katy

Dye9, Brad Matthews10, Phil Maxson11, Joseph

Sgherza12, Wendy Boone12, Vicki Chilton12 1Uganda Virus Research Institute, Entebbe,

Uganda, 2University of Nebraska Medical Center,

National Ebola Training and Education Center,

Omaha, NE, United States, 3United States Army

Medical Research Institute of Infectious Diseases,

Frederick, MD, United States, 4The Bill & Melinda

Gates Foundation, Seattle, WA, United

States, 5University of Liverpool, Liverpool, United

Kingdom, 6Albert Einstein College of Medicine, Bronx,

NY, United States, 7SBD Global, Gettysburg, PA,

United States, 8University of Toronto, Toronto, ON,

Canada, 9Mount St. Mary’s University, Emmitsburg,

MD, United States, 10Matthews Specialty Vehicles,

Greensboro, NC, United States, 11Lynden

International, Seattle, WA, United States, 12Integrum

Scientific, Greensboro, NC, United States

LB-5448

Perceptions about Transportation of Bodies

between Community and Health Facilities in a

Context of a Mortality Surveillance Programme

Rui Anselmo Guilaze

Manhica Health Research Centre, Manhiça-Maputo,

Mozambique

LB-5449

Integrated Community Case Management:

Review of governance, costing and financing

for sustainable health system integration

Koya C. Allen1, Kate Whitfield2, Salim Sadruddin3 1KCA Consulting, Brooklyn, NY, United

States, 2Instituto de Salud Global Barcelona

(ISGlobal), Barcelona, Spain, 3World Health

Organization, Geneva, Switzerland

LB-5450

Fetal growth pattern and poor perinatal

outcomes in southern Benin: comparison

between the new international WHO and

INTERGROWTH-21st fetal growth charts

Emmanuel Koffi YOVO1, Manfred ACCROMBESSI1,

Wiliam ATADE1, Titilola LADIKPO1, Abagnon DEGBE1,

Méhoba DEHOGBE1, Achille MASSOUGBODJI1, Nicolas

JACKSON2, Jennifer ZEITLIN3, Valérie BRIAND4 1Centre d’Etude et de Recherche sur le Paludisme

Associé à la Grossesse et à l’Enfance (CERPAGE),

Faculté des Sciences de la Santé, Université

d’Abomey-Calavi, Benin, Cotonou,

Benin, 2Department of Obstetrics and Gynaecology,

Oxford University, Oxford, UK., Oxford, United

Kingdom, 3National Institute of Health and Medical

Research Unité Mixte de Recherche 1153,

Obstetrical, Perinatal, and Pediatric Epidemiology

Research Team, Center for Epidemiology and

Biostatistics, Paris-Descartes University, Paris,

France., Paris, France, 4MERIT, IRD, Université Paris

Descartes, Sorbonne Paris Cité, France, Paris, France

LB-5451

Impact of meningococcal vaccination time

on Neisseria meningitidis carriage: A cross-

sectional study of pilgrims traveling to Mecca,

Saudi Arabia

Abrar Alasmari1, Joanna Houghton1, Brian

Greenwood1, David Heymann1, Phil Edwards1, Heidi

Larson1, Abdullah Assiri2, Fathia BenRached3, Arnab

Pain3, Amaya Bustinduy1, Ron Behrens1 1London school of hygiene and tropical medicine,

London, United Kingdom, 2Preventive Health,

Ministry of Health, Riyadh, Saudi Arabia, 3King

Abdullah University of Science and Technology

(KAUST), Thuwal-Jeddah, Saudi Arabia

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71

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5452

Resolution ofZaire ebolavirusTransmission

Among Geographically-Dispersed Family

Members in Liberia: Estimates of Key Epidemic

Parameters, Behaviors, Social Pressures, and

Failures of Epidemic Control Measures,

September—November 2014

Jennifer E. Giovanni1, Rebecca C. Christofferson1,

Christopher N. Mores2 1Louisiana State University, Baton Rouge, LA, United

States, 2The George Washington University,

Washington, DC, United States

LB-5453

Examination of morbidity and mortality due to

diabetes and assessment of diabetes-related

healthcare services in rural western Kenya

Kombewa health and demographic surveillance

systems site.

Alyssa Faith Purdy1, Peter Sifuna2, David A.

Larsen3, Lucas Otieno2, Kenedy O. Omolo2, Alizee

McLorg3, Andrea V. Shaw1 1SUNY Upstate, Syracuse, NY, United States, 2United

States Army Medical Research Directorate- Kenya,

Kombewa, Kenya, 3Syracuse University, Syracuse,

NY, United States

LB-5454

Mapping health indicators from remote sensing

imagery: data-driven approaches to filling

health information gaps

Mollie M. Van Gordon, Guillaume Chabot-Couture,

Joshua L. Proctor

Institute for Disease Modeling, Bellevue, WA, United

States

LB-5455

Early Life Interventions for Childhood Growth

and Development in Tanzania (ELICIT): study

rationale and baseline characteristics

Tarina C. Parpia1, Sarah E. Elwood1, Rebecca J.

Scharf1, Joann M. McDermid1, Anne W. Wanjuhi1,

Jean Gratz1, Erling Svensen2, Jonathan R. Swann3,

Jeffrey R. Donowitz4, Samwel Jatosh5, Eric R. Houpt1,

Mark D. DeBoer1, Estomih Mduma5, James A. Platts-

Mills1 1University of Virginia, Charlottesville, VA, United

States, 2University of Bergen, Bergen,

Norway, 3Imperial College London, London, United

Kingdom, 4Virginia Commonwealth University,

Richmond, VA, United States, 5Haydom Lutheran

Hospital, Haydom, Tanzania, United Republic of

LB-5456

Sepsis in Tropical Environments: Use of Locally

Available Data to Derive Clinically-Relevant

Patient Subgroups

Deborah A. Striegel1, Kevin L. Schully2, Josh G.

Chenoweth1, Anissa Elayadi1, George Oduro3, Daniel

Ansong3, Andrew Letizia4, Anne Fox5, Charmagne

Beckett2, Benjamin Espinosa2, Danielle V. Clark1 1Austere environments Consortium for Enhanced

Sepsis Outcomes (ACESO), Henry M. Jackson

Foundation for the Advancement of Military Medicine,

Bethesda, MD, United States, 2Austere environments

Consortium for Enhanced Sepsis Outcomes (ACESO),

Biological Defense Research Directorate, Naval

Medical Research Center, Frederick, MD, United

States, 3Komfo Anokye Teaching Hospital, Kumasi,

Ghana, 4Naval Medical Research Center, Silver

Spring, MD, United States, 5Naval Medical Research

Unit-3, Accra, Ghana

LB-5457

Optimizing cluster survey designs for

estimating trachomatous inflammation-

follicular within trachoma control programs

Julia W. Gallini1, Eshetu Sata2, Tigist Astale2, Mulat

Zerihun2, Berhanu Melak2, Melsew Chanyalew3,

Demelash Gessese2, Zebene Ayele2, Zerihun

Tadesse2, E. Kelly Callahan4, Scott D. Nash4, Paul

Weiss1 1Department of Biostatistics and Bioinformatics,

Emory University, Atlanta, GA, United States, 2The

Carter Center, Addis Ababa, Ethiopia, 3Amhara

Regional Health Bureau, Bahir Dar, Ethiopia, 4The

Carter Center, Atlanta, GA, United States

LB-5458

Redistribution of malaria risk by solar

geoengineering as a model for health impacts

in developing countries

Colin J. Carlson1, Shweta Bansal1, Rita Colwell2,

Mohammad Sharif Hossain3, Mohammed Mofizur

Rahman3, Alan Robock4, Christopher Trisos5,

Mohammad Shafiul Alam3 1Georgetown University, Washington, DC, United

States, 2University of Maryland, College Park, College

Park, MD, United States, 3International Centre for

Diarrhoeal Disease Research, Bangladesh, Dhaka,

Bangladesh, 4Rutgers University, New Brunswick, NJ,

United States, 5University of Cape Town, Cape Town,

South Africa

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72

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5459

Aedes aegypti risk mapping: using ovitrap data

to target mosquito breeding hotspots in

Guatemala

Julie Niemczura de Carvalho1, Jesús Dávila-

Barboza2, Julio D. Soto López3, M. Roberto Romero4,

Marianne Henry1, Arturo Sánchez López4 1MCDI, Silver Spring, MD, United States, 2MCDI,

Monterrey, Mexico, 3Vector-Borne Disease Program,

Guatemalan Ministry of Health and Social Assistance,

Guatemala City, Guatemala, 4MCDI, Guatemala City,

Guatemala

LB-5460

Assessing the threat of helminth infections to

U.S. military personnel

Alyssa R. Lindrose1, Indrani Mitra1, Jamie Fraser1,

Edward Mitre2, Patrick W. Hickey2 1Uniformed Services University of the Health

Sciences; Henry M. Jackson Foundation for the

Advancement of Military Medicine, Bethesda, MD,

United States, 2Uniformed Services University of the

Health Sciences, Bethesda, MD, United States

LB-5461

Analysis of neonatal and infant mortality rates

and risk factors in the Kombewa HDSS in

Kombewa, Kenya from 2011 to 2017

Casey Mohrien1, Andrea Shaw1, Peter Sifuna2,

Christina Lupone1, Alizée McLorg3, David Larsen3,

Kennedy Omolo4 1SUNY Upstate Medical, Syracuse, NY, United

States, 2US Army Medical Research Directorate-

Kenya/Kenya Medical Research Institute, Kisumu,

Kenya, 3Syracuse University, Syracuse, NY, United

States, 4US Army Medical Research Directorate-

Kenya/Kenya Medical Research Institute, Kisumu,

Kenya, Kisumu, Kenya

LB-5462

Rapid health zone mapping in the Democratic

Republic of the Congo: an overview and

evaluation of a low-cost, replicable

methodology for use during disease outbreaks

in resource-limited, data-poor settings

Cyrus S. Sinai1, Nicole A. Hoff2, Trevon Fuller2,

Kamy K. Musene3, D'Andre A. Spencer2, Frank Salet4,

Reena H. Doshi5, Patrick Mukadi6, Trevor Ayers2,

Bernice Selo7, Guillaume N. Mwamba8, Michel N.

Kabamba8, Michael E. Emch1, Sue Gerber9, Benoit I.

Kebela7, Emile Okitolonda-Wemakoy3, Anne W.

Rimoin2 1University of North Carolina at Chapel Hill,

Department of Geography, Chapel Hill, NC, United

States, 2University of California, Los Angeles Fielding

School of Public Health, Department of Epidemiology,

Los Angeles, CA, United States, 3Kinshasa School of

Public Health, Kinshasa, Democratic Republic of the

Congo, 4McKing Consulting Corporation, Atlanta, GA,

United States, 5Centers for Disease Control and

Prevention, Atlanta, GA, United States, 6Institut

National de Recherche Biomedicale, Kinshasa,

Democratic Republic of the Congo, 7DRC Ministry of

Public Health, Kinshasa, Democratic Republic of the

Congo, 8DRC Expanded Program for Immunization,

Kinshasa, Democratic Republic of the Congo, 9Bill

and Melinda Gates Foundation, Seattle, WA, United

States

LB-5463

Developing Fully Online Master’s Degrees in

Global Health

William R. Brieger, Elizabeth Golub, Cristina

Salazar, Christina Potter, Derin Dacey

The Johns Hopkins University, Baltimore, MD, United

States

LB-5464

Behavioral factors associated with sustained

breastfeeding in rural Northwest Ethiopia

Seblewongel Yigletu, Maureen Kamanu, Afua

Ofori-Darko, Abdi Wakene, Shalini A. Tendulkar,

Karen C. Kosinski

Tufts University, Medford, MA, United States

LB-5465

The prevalence and burden of chronic typhoid

carriage: a supplemental analysis to the Global

Burden of Disease Study 2017

Jeffrey D. Stanaway

IHME, University of Washington, Seattle, WA, United

States

LB-5466

Prevalence of congenital cytomegalovirus

infection in Western Kenya, 2015-2016

Nancy A. Otieno1, Martina Oneko1, Minal M. Amin2,

Bryan O. Nyawanda1, Arthur Odoyo1, Daniel Omollo1,

Michael Otieno1, Sheilla S. Dollard2, Tatiana M.

Lanzieri2 1Kenya Medical Research Institute, Kisumu,

Kenya, 2Centers for Disease Control and Prevention,

Atlanta, GA, United States

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73

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5467

HIV&AIDS STIGMATIZATION AMONG

NIGERIAN STUDENTS

MARGARET ARAOYE, Peter Akwu

KOGI STATE UNIVERSITY, ANYIGBA, Nigeria

LB-5468

The role of poly substance use and depression

on HIV disease progression in the Miami Adult

Studies on HIV (MASH) Cohort

Abraham Degarege1, Karl Krupp2, Marianna Baum3 1Department of Epidemiology, University of Nebraska

Medical Center, Omaha, NE, United

States, 2Department of Health Promotion Sciences,

University of Arizona, Tucson, AZ, United

States, 3Department of Dietetics and Nutrition,

Florida International University, Mimai, FL, United

States

LB-5469

Cross-border settings are in common for spatial

overlaps of TB and HIV in Ethiopia

Yalemzewod Assefa Gelaw

The University of Queensland, Brisbane, Australia

LB-5470

Significance of action of primaquine and

tafenoquine in Plasmodium vivax malaria

Miles B. Markus

University of the Witwatersrand, Johannesburg,

South Africa

LB-5471

An RH5 specific monoclonal antibody binding

outside of the basigin interaction site potently

inhibits in vitro red blood cell invasion by

Plasmodium falciparum

Giacomo Gorini1, Carolyn M. Nielsen1, Doris

Quinkert1, Amelia M. Lias1, Jordan R. Barrett1, Sarah

E. Silk1, Martino Bardelli1, Maria Zaric1, Katherine J.

Ellis1, Daniel G. Alanine1, Angela M. Minassian1,

Vinayaka Kotraiah2, Amy R. Noe2, Robin Miller3,

Carter L. Diggs3, Lorraine A. Soisson3, David Pulido1,

Matthew K. Higgins4, Simon J. Draper1 1Jenner Institute, University of Oxford, Oxford,

United Kingdom, 2Leidos Life Sciences, Frederick,

MD, United States, 3Malaria Vaccine Development

Program, United States Agency for International

Development, Washington, D.C., DC, United

States, 4Department of Biochemistry, University of

Oxford, Oxford, United Kingdom

LB-5472

Adequate reticulocyte responses and immune

tolerance limit the development of malarial

anemia in children with

asymptomatic Plasmodium falciparum malaria

infection in Burkina Faso

Berenger Kaboré1, Annelies Post2, Mike Berendsen2,

Salou Diallo1, Palpouguini Lompo1, Derra Karim1, Eli

Rouamba1, Jan Jacobs3, Halidou Tinto1, Quirijn de

Mast2, Andre J. van der Ven2 1IRSS/Clinical Research Unit of Nanoro (CRUN),

Nanoro, Burkina Faso, 2Radboud university medical

centre, Nijmegen, Netherlands, 3Department of

Clinical Sciences, Institute of Tropical Medicine

(ITM), Antwerp, Belgium

LB-5473

Measuring Genetic Relatedness Across

Plasmodium falciparum Parasite Populations

Accounting for Multiple Infections

Sophie Berube1, Giovanna Carpi2, Thomas A.

Louis1, William J. Moss1, Douglas E. Norris1, Julia C.

Pringle1, Amy Wesolowski1 1Johns Hopkins University Bloomberg School of

Public Health, Baltimore, MD, United States, 2Purdue

University, West Lafayette, IN, United States

LB-5474

Experimental evaluation of the effects of

traditional and clean cooking fuels on

Anopheles mosquito behavior and malaria risk

in Rwanda

Ian P. Hennessee1, Miles Kirby1, Thomas Clasen1,

Uriel Kitron2, Emmanuel Hakizimana3, Joshua

Rosenthal4 1Emory University, Rollins School of Public Health,

Atlanta, GA, United States, 2Emory University,

Department of Environmental Sciences, Atlanta, GA,

United States, 3Rwanda Ministry of Health, Rwanda

Biomedical Center, Malaria & Other Parasitic Disease

Division, Kigali, Rwanda, 4Fogarty International

Center, National Institutes of Health (NIH),

Bethesda, MD, United States

Page 75: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

74

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5475

Production and characterization of a malaria

transmission blocking vaccine candidate

Pvs230D1 for human clinical studies

Karine Reiter1, Vu Nguyen1, Martin Burkhardt1,

Richard Shimp1, Myriam Arevalo2, Olga Muratova1,

Lynn E. Lambert1, Kelly M. Rausch1, Raul Herrera1,

Socrates Herrera2, Nicholas J. MacDonald1, Patrick E.

Duffy1, David L. Narum1 1LMIV, NIAID/NIH, Bethesda, MD, United

States, 2Caucaseco Scientific Research Center and

Malaria Vaccine and Drug Development Center, Cali,

Colombia

LB-5476

Change in species composition and biting

behaviour of Anopheles mosquitoes in an

endemic area in northern Namibia

Tabeth Mwema1, Seth Eiseb1, Petrina Uusiku2,

Sheila Ogoma-Barasa3, Iitula Iitula2, Stark Katokele2,

Rosalia Joseph1, Cara Smith Gueye4, Elodie Vajda4,

Neil Lobo4, Davis Mumbengegwi1 1University of Namibia, Windhoek, Namibia, 2Ministry

of Health and Social Services, Windhoek,

Namibia, 3CHAI, Windhoek, Namibia, 4University of

California, San Francisco, San Francisco, CA, United

States

LB-5477

Risk Factors for Peripheral Malaria During

Pregnancy in Western Kenya

Will T. Eaton1, Fredrick Opinya2, Eric Dong1, Kenta

Okuyama3, Chelsea Stacy1, Chris White1, Jason Zhu1,

Elizabeth Okongo4, Ewa Knitter1, Rosemary

Rochford1 1Colorado School of Public Health, Aurora, CO, United

States, 2Kenya Medical Research Institute, Kisian,

Kenya, 3Centre for Primary Health Care Research,

Lund, Sweden, 4University of Eldoret, Eldoret, Kenya

LB-5478

Malaria Zero Plan in Peru: Preliminary

resultsand challenges

Alejandro Llanos-Cuentas1, Hugo Rodriguez2,

Cristian Carey2, Veronica Soto3, Dionicia Gamboa1,

Fiorela Alvarez1, Joseph Vinetz4, Karim Pardo3 1Institute of tropical medicine Alexander von

Humboldt, Lima, Peru, 2Dirección General de Salud

de Loreto, Ministerio de Salud (MINSA), Lima,

Peru, 3Dirección de prevención y control de

enfermedades metaxènicas y zoonosis, MINSA, Lima,

Peru, 4Department of Medicine, Yale University,

Lima, Peru

LB-5479

Malaria Parasitemia among Adult Blood Donors

for Children in the Federal Capital Territory,

Nigeria.

Nnakelu Eriobu1, Maryam Al-Mujtaba1, Titilayo I.

Bisi-Adeniyi1, Juliet I. Haruna1, Maryam Anibolowo1,

Blessing C. Eriobu1, Obiageli E. Nnodu2, Seyi

Oniyangi3, Adaora A. Okechukwu2, Tamunomieibi T.

Wakama3, Habib O. Ramadhani4, Miriam K.

Laufer5, Nadia A. Sam-Agudu1 1International Research Center of Excellence,

Institute of Human Virology Nigeria, Abuja,

Nigeria, 2University of Abuja Teaching Hospital,

Abuja, Nigeria, 3National Hospital Abuja, Abuja,

Nigeria, 4Institute of Human Virology, University of

Maryland School of Medicine, Baltimore, MD, United

States, 5Center for Vaccine Development, University

of Maryland School of Medicine, Baltimore, MD,

United States

LB-5480

Investigation into the Efficacy of Indoor

Residual Spraying and the Insecticide

Susceptibility Status of the Anopheles Mosquito

Population in Selected Malaria Endemic Regions

of Northern Namibia

Rosalia Joseph1, Seth Eiseb1, Petrina Uusiku2,

Sheila Ogoma-Barasa3, Iitula Iitula2, Stark Katokele2,

Tabeth Mwema1, Cara Smith Gueye4, Elodie Vajda4,

Neil Lobo4, Davis Mumbengegwi1 1University of Namibia, Windhoek, Namibia, 2Ministry

of Health and Social Services, Windhoek,

Namibia, 3CHAI, Windhoek, Namibia, 4University of

California, San Francisco, San Francisco, CA, United

States

LB-5481

Enhanced Antibody Response of a Particle-

Inducing, Liposome Vaccine Adjuvant Admixed

with a Pfs230 Fragment

Wei-Chiao Huang1, Bingbing Deng2, Amal Seffouh3,

Joaquin Ortega3, Carole Long2, Xuedan He1,

Kazutoyo Miura2, Shwu-Maan Lee4, Yimin Wu4,

Jonathan Lovell1 1University at Buffalo, Amherst, NY, United

States, 2Laboratory of Malaria and Vector Research,

National Institute of Allergy and Infectious

Diseases,National Institutes of Health, Rockville, MD,

United States, 3Department of Anatomy and Cell

Biology, McGill University, Montreal, QC,

Canada, 4PATH’s Malaria Vaccine Initiative (MVI),

DC, WA, United States

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75

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5482

A cobalt porphyrin liposomal adjuvant with

reduced MPLA, capability for lyophilization and

re-constitution, and thermostability

Moustafa Mabrouk1, Wei-Chiao Huang1, Kazutoyo

Miura2, Nasi Li-Purcell3, Gunes Ekin Atilla-

Gokcumen3, Amal Seffouh4, Joaquin Ortega4,

Jonathan Lovell1 1Biomedical Engineering Department, University at

Buffalo, Buffalo, NY, United States, 2Laboratory of

Malaria and Vector Research, National Institute of

Allergy and Infectious Diseases, National Institutes

of Health, Rockville, MD, United States, 3Department

of Chemistry, University at Buffalo, Buffalo, NY,

United States, 4Department of Anatomy and Cell

Biology, McGill University, Montreal, QC, Canada

LB-5483

Antibody titres do not predict the conversion of

asymptomatic children to developing

symptomatic malaria

Balotin Fogang1, Mathieu Schoenhals1, Franklin

Maloba2, Estelle Essangui1, Christiane Donkeu1, Marie

Abite1, Glwadys Cheteug1, Marie Kapen1, Rodrigue

Keumoe1, Sylvie Kemleu1, Rosette Megnekou3,

Tracey Lamb4, Lawrence Ayong5 1Centre Pasteur Cameroon and University of Yaounde

I, Yaounde, Cameroon, 2University of Utah, Salt Lake

City, UT, United States, 3University of Yaounde I,

Yaounde, Cameroon, 4University of Utah, Centre

Pasteur Cameroon and University of Yaounde I, Salt

Lake City, UT, United States, 5Centre Pasteur

Cameroon, Yaounde, Cameroon

LB-5484

IRS, MDA and SBC campaign performance and

coverage in Southern Province, Zambia through

application of in-field spatial intelligence

Derek Pollard1, Anne C. Martin1, Frazer Bwalya1,

Javan Chanda2, Reuben Zulu3, Emmanuel Kooma3,

Anna Winters1, John Miller1 1Akros, Lusaka, Zambia, 2PATH Malaria Control and

Elimination Partnership in Africa (MACEPA), Lusaka,

Zambia, 3National Malaria Elimination Centre,

Ministry of Health, Lusaka, Zambia

LB-5485

Contribution of CD8+T cells to severe malarial

anemia during P. coatneyi infection in Rhesus

macaques

Isha Pandey

National Institute of Health, Bethesda, MD, United

States

LB-5486

Spatial-temporal and methodological trends in

the molecular surveillance of drug resistant

malaria in sub-Saharan Africa

Hanna Y. Ehrlich, Justin Jones, Sunil Parikh

Yale University, New Haven, CT, United States

LB-5487

Optimizing the impact of Seasonal Malaria

Chemoprevention : improving delivery and

building capacity for evaluation

Jean Louis A. Ndiaye1, Eugene K. Lama2, Aurore

Ogouyèmi-Hounto3, Balla Kandeh4, Alioune Gueye5,

Dorothy Achu6, Keziah Malm7, Bala Audu8, Yacouba

Savadogo9, Idrissa Cisse10, Hadiza Jackou11, Tinah

Atcha-Oubou12, Doudou Sene5, Andre M.

Tchouatieu13, Corinne S. Merle14, Paul Milligan15 1University of Thies, Thies, Senegal, 2NMCP, Ministry

of Health, Conakry, Guinea, 3NMCP, Ministry of

Health, Cotonou, Benin, 4NMCP, Minstry of Health,

Banjul, Gambia, 5NMCP, Ministry of Health, Dakar,

Senegal, 6NMCP, Minstry of Health, Yaounde,

Cameroon, 7NMCP, Ministry of Health, Accra,

Ghana, 8NMEP, Ministry of Health, Abuja,

Nigeria, 9NMCP, Ministry of Health, Ouagadougou,

Burkina Faso, 10NMCP, Minstry of Health, Bamako,

Mali, 11NMCP, Ministry of Healh, Niamey,

Niger, 12NMCP, Minstry of Health, Lome,

Togo, 13Medicine for Malaria Venture, Geneva,

Switzerland, 14WHO/TDR, Geneva,

Switzerland, 15London School of Hygiene and Tropical

Medicine, London, United Kingdom

LB-5488

Measuring Gene Expression to Evaluate the

Effect of Artemether-Lumefantrine on

Parasitemia and Gametocytemia in Zambian

Children with Uncomplicated P. Falciparum

Malaria

Deborah M. Stiffler1, Matthew M. Ippolito2, Mwiche

P. Siame3, Philip E. Thuma4, V. Ann Stewart1 1Uniformed Services University of the Health

Sciences, Bethesda, MD, United States, 2Johns

Hopkins School of Medicine, Baltimore, MD, United

States, 3Ministry of Health, Lusaka, Zambia, 4Macha

Research Trust, Choma, Zambia

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76

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5489

Clinical and epidemiological profile of malaria

in ciudad Bolivar, Venezuela

David A. Forero-Peña1, Marisol Sandoval de Mora2,

Melynar Chavero1, Angel Gamardo1, Cariagne J.

Arenas-Leal1, Luisamy Figuera1, Natasha A. Camejo-

Avila1, Mariana Hidalgo3, Leopoldo Villegas4, M.

Andreina Pacheco5, Ananias A. Escalante6 1Biomedical Research and Therapeutic Vaccines

Institute, Ciudad Bolivar, Venezuela, Bolivarian

Republic of, 2Departamento de Medicina Interna,

Complejo Hospitalario Universitario “Ruíz y Páez”.,

Ciudad Bolívar, Venezuela, Bolivarian Republic

of, 3Instituto Venezolano de Investigaciones

Científicas (IVIC), Miranda, Venezuela, Bolivarian

Republic of, 4Asociación Civil Impacto Social

(ASOCIS), Tumeremo, Venezuela, Bolivarian

Republic of, 5Institute of Genomics and Evolutionary

Medicine, Temple University, Philadelphia, PA, United

States, 6BInstitute of Genomics and Evolutionary

Medicine, Temple University, Philadelphia, PA, United

States

LB-5490

Mosquitocidal activity of a long lasting

formulation of Ivermectin to be used against

Malaria

Hermann S. Pooda1, Lamidi Zéla1, Nicolas Moiroux2,

Anne-Laure Courjaud3, Marie-Sophie Martina3, Olga

Siscan3, Wilhem Leconet4, Christophe Roberge3,

Jean-Baptiste Rayaissé5, Roch K. Dabiré6, Karine

Mouline7 1Université de DIébougou, Diébougou, Burkina

Faso, 2Institut de Recherche pour le Développement,

Bobo Dioulasso, Burkina Faso, 3MedIncell, Jacou,

France, 4Weill Cornell Medical College-New York

Presbytérien Hospital, New York, NY, United

States, 5Centre International de Recherche-

Développement pour l'Elevage en zone Sub-humide,

Bobo Dioulasso, Burkina Faso, 6Institut de Recherche

en Sciences de la Santé-Direction Régionale de

l'Ouest, Bobo Dioulasso, Burkina Faso, 7Institut de

Recherche pour le Développement, Montpellier,

France

LB-5491

Performance ofmalachite green loop-mediated

isothermal amplification (MG-LAMP) and ultra-

sensitive RDT formalaria diagnosis in

Madagascar

Tovo Rakotomanga1, F. Ralinoro1, R. Raherinjafy1,

Brian Ezema2, T. Rakotomanjaka1, TH

Andriamandimbisoa1, S. Rabearimanana1, Laura

Steinhardt2, Peter Zimmerman3, Naomi Lucchi2,

Arsene Ratsimbasoa1 1National Malaria Control Program, Antananarivo,

Madagascar, 2Centers for Disease Control and

Prevention, Atlanta, GA, United States, 3Case

Western Reserve, Cleveland, OH, United States

LB-5492

Selection for parasite resistance markers

during seasonal malaria chemoprevention with

sulfadoxine-pyrimethamine and amodiaquine

and other interventions in Mali

Hamma Maiga1, Amadou Bamadio2, Aliou Traore2,

Nouhoum Diallo2, Modibo Diarra2, Issaka Sagara2,

Samba Coumare2, Boubou Sangare2, Yeyia Dicko2,

Aly Tembely2, Djibril Traore2, Hamidou Niangaly2,

François Dao2, Aboubecrine Haidara2, Alassane

Dicko2, Ogobora Doumbo2, Patrick E. Duffy1,

Abdoulaye Djimde2 1LMIV, NIAID/NIH, Bethesda, MD, United

States, 2Malaria Research and Training

Center/DEAP/USTTB, Bamako, Mali

LB-5493

Ultra-sensitive molecular protocols for the

detection of Plasmodium genus and the five

human species: applicability in control or

elimination programs and in reference centers

Silvia M. Di Santi, Mariana Aschar, Maria de

Lourdes Farinas, Maria de Jesus C. Nascimento,

Maria Carmen A. Sanchez, Angelica D. Hristov,

Giselle F. Lima, Juliana Inoue, José E. Levi

São Paulo University, São Paulo, Brazil

LB-5494

Asymptomatic Plasmodium infections in blood

donor candidates in low endemic areas for

malaria: are molecular tools enough to prevent

the risk?

Maria Carmen A. Sanchez1, Silvia M. Di Santi1,

Mussya C. Rocha1, Ruth T. Portillo1, Mahyumi

Fujimori1, Giselle F. Lima1, Maria de Jesus C.

Nascimento2, Alfredo Mendrone Junior3, José E. Levi1 1São Paulo University, São Paulo, Brazil, 2SUCEN,

São Paulo, Brazil, 3Pró-Sangue Foundation, São

Paulo, Brazil

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77

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5495

Challenges implementing mobile phone-based

data collection in Mopeia, Mozambique

Eldo Elobolobo1, Binete Savaio2, Amilcar Nacima1,

Christelle Gogue2, Molly Robertson2, Carlos

Chaccour3, Francisco Saúte1, Amilcar Magaco1 1Centro de Investigação em Saúde de Manhiça,

Maputo, Mozambique, 2PATH, Washington, DC,

United States, 3ISGlobal, Hospital Clínic - Universitat

de Barcelona, Barcelona, Spain

LB-5496

Massively parallel immunological profiling of

antibody responses to Plasmodium falciparum

using phage display

Madhura Raghavan1, Elias Duarte1, Katrina L.

Kalantar2, Isabel Rodriguez-Barraquer1, Noam

Teyssier1, Andrew Kung1, Saki Takahashi1, Inna

Gerlovina1, John Rek3, Kevin K.A. Tetteh4, Chris

Drakeley4, Isaac Ssewanyana3, Joseph L. DeRisi1,

Bryan Greenhouse1 1University of California San Francisco, San

Francisco, CA, United States, 2Chan Zuckerberg

Biohub, San Francisco, CA, United States, 3Infectious

Disease Research Collaboration, Kampala,

Uganda, 4London School of Hygiene & Tropical

Medicine, London, United Kingdom

LB-5497

Calxinin: Novel hydroxyethylamine-based

piperazine compound with multi-stage

antiparasitic activity and known mechanism of

action for treating P. falciparum malaria

Brijesh Rathi1, Snigdha Singh2, Yash Gupta3, Neha

Sharma2, Poonam FNU4, Hoseah M. Akala5, Whelton

A. Miller III6, Jesus G Romero3, Stefan M Kanzok7,

Walter Jeske3, Ravi Durvasula8, Agam P

Singh9, Prakasha Kempaiah3 1Department of Chemistry, Hansraj College

University Enclave, University of Delhi, Delhi,

110007, India and Loyola University Chicago Stritch

school of Medicine, Maywood, IL, United

States, 2Department of Chemistry, Hansraj College

University Enclave, University of Delhi, Delhi,

110007, India and Loyola University Chicago Stritch

school of Medicine, Maywood, IL, United States,

Maywood, IL, United States, 3Loyola University

Chicago Stritch school of Medicine, Maywood, IL,

United States, 4Department of Chemistry, Miranda

House, University of Delhi, Delhi 110007 India and

Loyola University Chicago Stritch school of Medicine,

Maywood, IL, United States, Maywood, IL, United

States, 5Kenya Medical Research Institute (KEMRI),

Kisumu and Nairobi, Kenya; Loyola University Chicao

Stricth school of Medicine, Maywood, IL, United

States, Maywood, IL, United States, 6Loyola

University Chicao Stritch school of Medicine,

Maywood, IL, United States, 7Loyola University

Chicago, Chicago, IL, United States, 8Loyola

University Chicago Stricth school of Medicine and

Department of Medicine, Loyola University Medical

Center, Maywood, IL, United States, 9Infectious

Diseases Laboratory, National Institute of

Immunology, Aruna Asaf Ali Marg,110067, New

Delhi, India

LB-5498

Methodology of observational analyses to

evaluate the impact of new net distributions in

Burkina Faso, Mozambique, Rwanda, and

beyond

Molly Robertson1, Baltazar Candrinho2, Yacouba

Savadogo3, Adama Gansane4, Sagnon NFalé4,

Moussa Guelbeogo4, Aimable Mbituyumuremyi5,

Emmanuel Hakizimana5, Chantal Ingabire6, Joseph

Wagman1, Christelle Gogue1, Kenzie Tynuv1, Peder

Digre7, Christen Fornadel8, Hilary Ranson9, Federica

Guglielmo9, Patrick Okello10, Kate Kolaczinski10,

Laurence Slutsker7 1PATH, Washington, DC, United States, 2National

Malaria Control Program, Ministry of Health, Maputo,

Mozambique, 3National Malaria Control Program,

Ministry of Health, Ouagadougou, Burkina

Faso, 4Centre National de Recherche et de Formation

sur le Paludisme, Ouagadougou, Burkina

Faso, 5Rwanda Biomedical Center, Kigali,

Rwanda, 6University of Rwanda, Kigali,

Rwanda, 7PATH, Seattle, WA, United States, 8IVCC,

Liverpool School of Tropical Medicine, Liverpool,

United Kingdom, 9Liverpool School of Tropical

Medicine, Liverpool, United Kingdom, 10The Global

Fund to Fight AIDS, Tuberculosis and Malaria,

Geneva, Switzerland

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78

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5499

Cost and cost-effectiveness of third-generation

indoor residual spraying in sub-Saharan Africa:

Results of data collection and analysis in the

Next Generation IRS project

Joshua Yukich1, Sara Scates1, Luc Boydens2,

Emmanuel Ubachukwu Obi Onyefunafoa2, Nicky

Moran2, Mariandrea Chamorro3, Benjamin Johns3,

Seydou Fomba4, Keziah L. Malm5, Lena Kolyada6,

Baltazar Candrinho7, Rodaly Muthoni8, Jimmy Opigo9,

Catherine Maiteki-Sebuguzi9, Damian Rutazaana9,

Josephat Shililu10, Emmanuel Kooma11, Anna

Winters12, Annie Martin12, Peder Digre13, Joseph

Wagman14, Molly Robertson14 1Tulane University School of Public Health and

Tropical Medicine, New Orleans, LA, United

States, 2Tropical Health Consulting LLP, London,

United Kingdom, 3Abt Associates, Rockville, MD,

United States, 4Programme National de Lutte contre

le Paludisme, Bamako, Mali, 5National Malaria

Control Program, Ministry of Health, Accra,

Ghana, 6PMI VectorLink Ghana Project, Abt

Associates, Accra, Ghana, 7National Malaria Control

Program, Ministry of Health, Maputo,

Mozambique, 8PMI VectorLink Mozambique, Abt

Associates, Maputo, Mozambique, 9National Malaria

Control Division, Ministry of Health, Kampala,

Uganda, 10PMI VectorLink Uganda Project, Abt

Associates, Kampala, Uganda, 11National Malaria

Elimination Centre, Lusaka, Zambia, 12Akros, Inc.,

Lusaka, Zambia, 13PATH, Seattle, WA, United

States, 14PATH, Washington, DC, United States

LB-5500

Assessing adjuvant-specific differences

through immunoprofiling of vaccine-induced

immune responses using machine learning

Michele D. Spring1, Siddartha Chaudhury2,

Elizabeth H. Duncan2, Sheetij Dutta2, Elke S.

Bergmann-Leitner2 1Armed Forces Research Institute of Medical

Sciences, APO, AE, United States, 2Walter Reed Army

Institute of Research, Silver Spring, MD, United

States

LB-5501

Elderly Person Severe Malaria Profile in

Kinshasa DR Congo

Huguette Tchamba1, Frederic Kabasele2, Solange

Umesumbu3, Thierry L. Bobanga2 1University of Technology Bel Campus, KINSHASA,

Democratic Republic of the Congo, 2University of

Kinshasa, KINSHASA, Democratic Republic of the

Congo, 3National malaria Control Program,

KINSHASA, Democratic Republic of the Congo

LB-5502

Impact evaluation of a health systems

strengthening project on intermittent

preventive treatment (IPTp) intake during

pregnancy in the Democratic Republic of the

Congo: Findings from a 2014 and 2017 cross

sectional household surveys

Renad J. Jadkarim1, David Hotchkiss2, Janna

Wisniewski3, Joshua Yukich1, Julie Hernandez3,

Joseph Keating1 1Department of Tropical Medicine, Tulane University

School of Public Health & Tropical Medicine, New

Orleans, LA, United States, 2Department of Global

Community Health and Behavioral Sciences, Tulane

University School of Public Health & Tropical

Medicine, New Orleans, LA, United

States, 3Department of Global Health Management

and Policy, Tulane University School of Public Health

& Tropical Medicine, New Orleans, LA, United States

LB-5503

Liposomes Containing Cobalt Porphyrin-

Phospholipid for Spontaneous Nanoliposomal

Antigen Particleization and Enhanced

Immunogenicity

Jonathan Lovell

SUNY Buffalo, Buffalo, NY, United States

LB-5504

Applying design-thinking to malaria control and

surveillance: An engineering case study in sub-

Saharan Africa

Sophia Diaz, Monet Slinowsky, Tristan Ford,

Ebenezer Armah, Karina Frank, Kiley Gersch,

Zachary Buono, Adam Goodwin, Margaret Glancey,

Soumyadipta Acharya

Johns Hopkins University, Baltimore, MD, United

States

LB-5505

Care Management Of Severe Malaria At The

Kinshasa General Provincial Reference Hospital

SOLANGE Efundu UMESUMBU

National malaria control program, KINSHASA,

Democratic Republic of the Congo

Page 80: ommitt hroug LATE-BREAKER ABSTRACTS of PRESENTATION SCHEDULE · 4 Late-Breaker Abstract Session 79 Late-Breakers in Basic Sciences Oral Presentations National Harbor 3 (National Harbor

79

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5506

Spatial analysis and epidemiological trend of

malaria in Thailand from 2012 to 2017

Nattwut Ekapirat1, Prayuth Sudathip2, Suravadee

Kitchakarn2, Darin Areechokchai2, Richard James

Maude3 1Mahidol-Oxford Tropical Medicine Research Unit,

Bangkok, Thailand, 2Vector Borne Diseases Division,

Department of Disease Control, Ministry of Public

Health, Nonthaburi, Thailand, 3Centre for Tropical

Medicine and Global Health, Nuffield Department of

Medicine, University of Oxford, Oxford, United

Kingdom

LB-5507

Natural immunity toPlasmodium vivaxin the

Peruvian Amazon shows broad pre erythrocytic

specificity

Lorena Tapia1, Julio Ventocilla1, Reynaldo Ponce1,

Danett Bishop1, Brandon Keith Wilder2 1NAMRU-6, Lima, Peru, 2OHSU/NAMRU-6, Beaverton,

OR, United States

LB-5508

Proteomic analysis of protein alterations in the

host induced by Leishmania

amazonensis or Leishmania infantum

Fernanda Negrao1, Selma Giorgio1, Marcos

Nogueira Eberlin2, John R. Yates III3 1UNICAMP, Campinas, Brazil, 2Mackenzie

Presbyterian University, São Paulo, Brazil, 3Scripps

Research, San Diego, CA, United States

LB-5509

Lysyl tRNA synthetase as a drug target in

apicomplexan parasites

Neil R. Norcross1, Beatriz Baragana1, Barbara

Forte1, Kevin D. Read1, Ian H. Gilbert1, Paul Willis2,

Chris Walpole3, Wesley C. Van Voorhis4 1Drug Discovery Unit, University of Dundee, Dundee,

United Kingdom, 2Medicines For Malaria Venture,

Geneva, Switzerland, 3Structure-guided Drug

Discovery Coalition (SDDC), Structural Genomics

Consortium, Toronto, ON, Canada, 4University of

Washington (UW), Center for Emerging and

Reemerging Infectious Disease (CERID), Seattle

Structural Genomics Center for Infectious Disease

(SSGCID), Seattle, WA, United States

LB-5510

Earlier diagnosis of canine infection

byLeishmania infantumusing immunoenzymatic

assay (ELISA) with rK39 or rK28

Hiro Goto1, Mahyumi Fujimori1, Maria Carmen

Arroyo Sanchez1, Roberto Mitsuyoshi Hiramoto2, José

Eduardo Tolezano2, Valéria Régia Franco Sousa3,

Arleana do Bom Parto Ferreira de Almeida3, Nazaré

Fonseca Souza4, Flaviane Alves de Pinho5, Steven

Reed6, Malcolm Scott Duthie6, Rodrigo Martins

Soares1, Luiz Ricardo Cortez1 1São Paulo University, São Paulo, Brazil, 2Adolfo Lutz

Institute, São Paulo, Brazil, 3Federal University of

Mato Grosso, Cuiabá, Brazil, 4Federal Rural

University of Amazônia, Belém, Brazil, 5Federal

University of Bahia, Salvador, Brazil, 6Infectious

Disease Research Institute, Seatle, WA, United

States

LB-5511

Post-Kala-Azar Dermal Leishmaniasis as a

Reservoir for Visceral Leishmaniasis

Transmission

Epke Le Rutte1, Eduard E. Zijlstra2, Sake J. de Vlas1 1Erasmus MC, Rotterdam, Netherlands, 2Rotterdam

Centre for Tropical Medicine, Rotterdam, Netherlands

LB-5512

Treatment of Intestinal Protozoa in Pregnancy:

A Systematic Review of Maternal, Fetal and

Infant Outcomes

Saniya Mansuri1, Rachel Lau2, Swana

Kopalakrishnan1, Celine Lecce1, Robert Chris1, Aisha

Khatib1, Sharmistha Mishra3, Andrea K. Boggild4 1Tropical Disease Unit, Toronto General Hospital,

Toronto, ON, Canada, 2Public Health Ontario

Laboratories, Toronto, ON, Canada, 3LI Ka Shing

Knowledge Institute, St. Michael's Hospital, Toronto,

ON, Canada, 4Tropical Disease Unit, Toronto General

Hospital and University of Toronto, Toronto, ON,

Canada

LB-5513

Molecular Diagnosis of Parasites in Stool in

Returning Travelers with Chronic Diarrhea at

the Sheba Medical Center in Israel

Shiraz Gefen-Halevi, Asaf Biber, Zeala Gazit,

Nathan Keller, Gill Smollan, Eli Schwartz

The Chaim Sheba medical center, Ramat Gan, Israel

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80

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5514

Variations in cervical microbiota in women with

positive and negative HPV infection

Hugo Carrillo-Ng1, Lorena Becerra-Goicochea2,

Juana del Valle-Mendoza3, Luis Pinillos-Vilca2, Carlos

Palomares-Reyes3, Carmen Tinco-Valdez3, Yordi

Tarazona-Castro4, Wilmer Silva-Caso3, Miguel Angel

Aguilar-Luis3, Luis J. del Valle5 1Instituto de Investigación Nutricional, Lima,

Peru, 2Hospital Regional Docente de Cajamarca,

Cajamarca, Peru, 3Research and Innovation Centre of

the Faculty of Health Sciences. Universidad Peruana

de Ciencias Aplicadas., Lima, Peru, 4Facultad de

Ciencias Biologicas. Universidad Nacional Mayor de

San Marcos., Lima, Peru, 5Barcelona Research Center

for Multiscale Science and Engineering, Departament

d'Enginyeria Química, EEBE, Universidad Politecnica

de Catalunya (UPC), Barcelona, Spain

LB-5515

The differential impact of types of disruptive

events on Ebola virus transmission: a

mathematical modeling study during the 2018-

2019 Ebola virus disease outbreak in the

Democratic Republic of the Congo

John D. Kelly1, S. Rae Wannier1, Nicole A. Hoff2,

Bernice Selo3, Mathais Mossoko3, Emile Okitolonda-

Wemakoy4, George Rutherford1, Thomas Lietman1,

Jean Jacques Muyembe5, Anne W. Rimoin2, Travis C.

Porco1, Eugene T. Richardson6 1UCSF, San Francisco, CA, United States, 2UCLA, Los

Angeles, CA, United States, 3MOH, Kinshasa,

Democratic Republic of the Congo, 4KPSH, Kinshasa,

Democratic Republic of the Congo, 5INRB, Kinshasa,

Democratic Republic of the Congo, 6HMS, Boston,

MA, United States

LB-5516

Impact of Baseline Immune Profile

(Monotypic/Multitypic) on CYD-TDV Dengue

Vaccine Performance in Dengue Seropositive

Individuals

Carlos A. DiazGranados1, Edith Langevin2,

Matthew Bonaparte1, Saranya Sridhar2, Tifany

Machabert2, Gustavo Dayan1, Rémi Forrat2, Stephen

Savarino1 1Sanofi Pasteur, Swiftwater, PA, United

States, 2Sanofi Pasteur, Marcy l'Etoile, France

LB-5517

A case of uveitis in a rhesus macaque following

survival of experimental Ebola virus infection

Gabriella Worwa1, Danny Ragland1, Russell

Byrum1, Kaleb Sharer1, Steven Yeh2, Jessica

Shantha2, Ji Hyun Lee1, Jonathan Kurtz1, Ricky

Adams1, Dima Hammoud3, Nina Aiosa1, Timothy

Cooper1, Amanda Bonilla1, Nejra Isic1, Erika Maynor1,

Christopher Bartos1, Philip Sayre1, Joseph Laux1,

Tracey Burdette1, Karlton Churchwell1, Nicolette

Schuko1, Colin Waters1, Kyra Hadley1, David

Drawbaugh1, Zachary Hubble1, Ian Crozier1, Louis

Huzella1, Marisa St. Claire1, Irwin Feuerstein1, Carl

Davis2, Rafi Ahmed2, Erica Ollmann Saphire4, Michael

Holbrook1 1National Institute of Allergy and Infectious Diseases,

Fort Detrick, MD, United States, 2Emory University,

Atlanta, GA, United States, 3National Institutes of

Health, Bethesda, MD, United States, 4La Jolla

Institute for Immunology, San Diego, CA, United

States

LB-5518

External Validation in the Democratic Republic

of Congo of an Ebola Severity Score for

Management of Patients with Confirmed Ebola

Virus Disease

Andres Colubri

Broad Institute, Cambridge, MA, United States

LB-5519

Dengue virus seroprevalence and

seroconversion in an adult population in

Medellín Colombia during 2012 to 2014

Peifang Sun1, Vihasi Jani2, Ying Cheng2, Ivan D.

Velez3, Jorge E. Osorio4, Maya Williams1 1Naval Medical Research Center, Silver Spring, MD,

United States, 2Henry Jackson Foundation, Bethesda,

MD, United States, 3Universidad de Antioquia,

Medellin, Colombia, Medellin, Colombia, 4University

of Wisconsin, Madison, Madison, WI, United States

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81

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5520

Higher risk for Zika virus seropositivity among

sexual partners of index patients from Recife,

Brazil, two years after the outbreak

Tereza Magalhaes1, Clarice N. Morais2, Ana M.

Brito2, Iracema J. Alves2, Elisa A. Azevedo2, Priscila

M. Castanha3, Marli T. Cordeiro2, Priscilla V. Lima2,

Andreza R. Lima2, Gabriella M. Moraes2, Lucelia S.

Pereira4, Janio A. Alves-Filho2, Thomas Jaenisch5,

Ernesto T. Marques3, Brian D. Foy1 1Colorado State University, Fort Collins, CO, United

States, 2Aggeu Magalhaes Institute, Recife,

Brazil, 3University of Pittsburgh, Pittsburgh, PA,

United States, 4Department of Health of Paulista,

Paulista, Brazil, 5Colorado School of Public Health,

Aurora, CO, United States

LB-5521

Arbovirus Surveillance in Oklahoma

Katelyn Helwig1, Noah Pelletier1, Christian Escritt2,

Bailee Cummings3, Kayla Thomas1, Caio Martinelle B.

França1 1Department of Biology, Southern Nazarene

University, Bethany, OK, United States, 2Department

of Chemistry, Southern Nazarene University,

Bethany, OK, United States, 3College of Medicine,

University of Arkansas for Medical Sciences, Little

Rock, AR, United States

LB-5522

Post-Ebola syndrome differs between

adolescents and adults: evidence from an

ongoing cohort study in Eastern Sierra Leone

Nell Bond1, Emily Engel1, Lansana Kanneh2, Robert

Samuels2, Adaora Okali1, Jeffrey Shaffer1, Donald

Grant2, John Schieffelin1 1Tulane University, New Orleans, LA, United

States, 2Kenema Government Hospital, Kenema,

Sierra Leone

LB-5523

Importance of pediatric astrovirus

gastroenteritis in Nicaragua

Yaoska Reyes1, Marta Diez-Valcarce2, Fredman

González1, Lester Gutierrez1, Christian Toval-Ruíz1,

Nadja Vielot3, Sylvia Becker-Dreps3, Jan Vinje2,

Filemón Bucardo1 1UNAN-Leon, Leon, Nicaragua, 2Centers for Disease

Control and Prevention, Atlanta, GA, United

States, 3School of Medicine, University of North

Carolina at Chapel Hill, Chapel Hill, NC, United States

LB-5524

Antibody-mediated immunity in Ebola Virus

Disease Survivors

Kayla Shore1, Iris Bica1, Augustine Goba2, Lansana

Kanneh2, Mambu Momoh2, Robert Samuels2, Ashley

Smira1, Donald Grant2, James Robinson1, John

Schieffelin1 1Tulane University, New Orleans, LA, United

States, 2Kenema Government Hospital, Kenema,

Sierra Leone

LB-5525

The use of a mobile application and Geographic

Information System (GIS) for disease

surveillance and control of Dengue in Thailand

Tanong Kumsri1, Richard James Maude2, Navarat

Singkum1, Rapeephan R. Maude2 1Buntharik Hospital, Ubon Ratchathani,

Thailand, 2Mahidol-Oxford Tropical Medicine

Research Unit, Bangkok, Thailand

LB-5526

Measles: public Health Emergency in Sao Paulo,

Brazil

Ana Freitas Ribeiro, Andrea Losacco, Aparecida

Klimas, Ana Paula Veiga, Celia Guarnieri, Ricardo

Manfredo, William Silva, Igor Melo, Marilia Kanebley,

Maira Felix, Rodovaldo Lucas Junior, Francisco

Pascalichio, Roberta Cavalin, Jamal Suleiman,

Marileide Vasconcelos

Institute of Infectology Emilio Ribas, Sao Paulo,

Brazil

LB-5527

Evaluation of Dengue Serological Tests

Available in Puerto Rico for Identification of

Prior Dengue Infection and Pre-vaccination

Screening

Matthew Bonaparte1, James Huleatt1, Shekema

Hodge1, Lingyi Zheng1, Carlos A. DiazGranados1,

Yasemin Ataman-Önal2, Stephen J. Savarino1 1Sanofi Pasteur, Switfwater, PA, United

States, 2Sanofi Pasteur, Marcy l'Etoile, France

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82

Poster Session C

Late-Breakers in Clinical and Applied Sciences

Saturday, November 23, Noon - 1:45 p.m.

LB-5528

Access to alcohol-based hand sanitizer is

associated with improved healthcare worker

hand hygiene in an Ebola-threatened district of

Western Uganda

Matthew Lozier1, Maureen Kesande2, Patricia

Akers1, Olive Tumuhairwe3, Martin Watsisi4, Winifred

Omuut2, Margaret Person1, Mohammed Lamorde2,

Jennifer Murphy1, Rob Quick1, David Berendes1 1Centers for Disease Control and Prevention, Atlanta,

GA, United States, 2Infectious Disease Institute,

Kampala, Uganda, 3District Health Office, Fort Portal,

Uganda, 4IRC-WASH, Fort Portal, Uganda

LB-5529

Comparison of Loop Mediated Isothermal

Amplification (LAMP) Assay to RT-PCR for West

Nile Virus Detection in Mosquitos

Kajal Patel, Pushker Raj, Brandon Williams,

Anthony Tran

DC Department of Forensic Sciences, Washington,

DC, United States

LB-5530

Implementing integrated WASH, nutrition, and

early childhood development interventions -

community health workers’ experiences from

Bangladesh

Tania Jahir1, Md. Mahbubur Rahman1, Elli

Leontsini2, Farzana Yeasmin1, Stephen P. Luby3,

Peter J. Winch2 1International Centre for Diarrheal Disease Research,

Bangladesh, Dhaka, Bangladesh, 2John Hopkins

Bloomberg School of Public Health, Baltimore, MD,

United States, 3Stanford University, Stanford, CA,

United States

LB-5531

Using GIS to develop cholera risk map for

emergency preparedness in Greater Accra,

Ghana

Hector N. Samani

University of Nebraska at Omaha, Omaha, NE,

United States

LB-5532

Induction of epigenetic changes by

agrochemicals - a possible explanation for

chronic kidney disease of unknown etiology

Abigail E. Bideaux1, Ramya Bhargava1, Rachel

Sippy1, Sriram S. Narsipur1, Anna M. Stewart-Ibarra2 1SUNY Upstate Medical University, Syracuse, NY,

United States, 2InterAmerican Institute for Global

Change Research, Montevideo, Uruguay

LB-5533

Understanding the Ecological and

Immunological Dynamics of Typhoid and

Paratyphoid in Preparation for Typhoid

Conjugate Vaccine Roll-out

Ruthie Birger1, Neil Saad1, Abhilasha Karkey2,

Buddha Basnyat2, Stephen Baker3, William Boos4,

Virginia Pitzer1 1Yale School of Public Health, New Haven, CT, United

States, 2Oxford University Clinical Research Unit,

Patan Academy of Health Sciences, Kathmandu,

Nepal, 35Department of Medicine, University of

Cambridge, Cambridge, United

Kingdom, 4Department of Earth & Planetary Science,

University of California, Berkeley, Berkeley, CA,

United States

LB-5534

Preliminary Data on Total Mercury in Hair

Samples in Northern Peru

Lauralee J. Fernandez1, Ricardo Gamboa2, Percy

Vilchez2, Claudio Muro2, Hugo H. Garcia2, William

Lambert1, Caren Weinhouse1, Molly Kile3, Sarah E.

Rothenberg3, Seth E. O'Neal1 1Oregon Health & Science University, Portland, OR,

United States, 2Universidad Peruana Cayetano

Heredia, Lima, Peru, 3Oregon State University,

Corvallis, OR, United States

LB-5535

Gold Mining Runoff in the Puyango-Tumbes

River: Human Health Risk Assessment

Lauralee J. Fernandez, Pailyn Brown, Eunhee

Heller, Lela Brown, Tawnya Peterson

Oregon Health & Science University, Portland, OR,

United States

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83

Presenter Index

A

Achee, Nicole LB-5276

Achur, Rajeshwara LB-5418

Ahmadova, Fidan LB-5416

Aksoy, Emre LB-5010

Aladeniyi, Isaac LB-5086

Alafo, Celso LB-5007

Alasmari, Abrar LB-5451

Ali, Inshan LB-5177

Allee-Munoz, Alec LB-5120

Allen, Koya LB-5449

Allwell-Brown, Gbemisola

LB-5274

Altcheh, Jaime LB-5173

Althubaiti, Nouf LB-5399

Aluisio, Adam LB-5343

Alvarez, María LB-5287

Amaro, I. Alexandra LB-

5359

Ambler, Gwen LB-5085

Ameen, Eve LB-5095

Amegashie, Elikplim LB-

5040

Amidou, Diarra LB-5216

Amo, Laura LB-5031

Anderson, Elizabeth LB-

5079

Ansdell, Vernon LB-5098

Araj, Brittany LB-5191

Araoye, Margaret LB-5467

Arca, Bruno LB-5432

Armstrong, Philip LB-5353

Artzberger, Georgia LB-

5220

Arzika, Ahmed LB-5261

Asare, Kwame LB-5400

Ashbaugh, Hayley LB-5262

Atayde, Alexandra LB-5097

Atiku, Linda LB-5266

Ayalneh, Belete LB-5054

Ayers, Victoria LB-5426

B

Badiane, Aida LB-5218

Badji, Henry LB-5256

Bagamian, Karoun LB-5015

Bakari, Catherine LB-5204

Baldwin, Whitney LB-5165

Banda, James LB-5324

Bargieri, Daniel LB-5043

Barr, Kelli LB-5357

Barrett, Jordan LB-5114

Barrios-Lopez, Brianda LB-

5056

Barry, Alyssa LB-5536

Bengtsson, Rebecca LB-

5250

Bennett, Hamilton LB-5344

Berge, Grifin LB-5226

Berger, Duncan LB-5230

Bernatchez, Jean LB-5374

Bertozzi-Villa, Amelia LB-

5281

Berube, Sophie LB-5473

Betancourt, Elena LB-5161

Biber, Asaf LB-5339, LB-

5513

Bideaux, Abigail LB-5532

Birger, Ruthie LB-5533

Bishop, Anusha LB-5179

Blatt, Daniel LB-5143

Blight, Joshua LB-5131

Bobanga, Thierry LB-5501

Bond, Nell LB-5522

Bonilla, Brian LB-5004

Boyce, Ross LB-5126

Brashear, Awtum LB-5050

Bratcher, Anna LB-5444

Brieger, William LB-5463

Buddhari, Darunee LB-

5341

Buss, Imogen LB-5264

C

Camarano Eula, Maria

Andrea LB-5116

Candrinho, Baltazar LB-

5147, LB-5286

Carlson, Colin LB-5458

Carrasco-Escobar, Gabriel

LB-5072

Carrillo-Ng, Hugo LB-5514

Carter, Tamar LB-5207

Castellanos-Gonzalez,

Alejandro LB-5227

Cespedes, Nora LB-5405

Chairuksa, Suparat LB-

5000

Chambrion, Charlotte LB-

5386

Checkley Needham, Lisa

LB-5390

Chelebieva, Sevil LB-5315

Cheng, Breagh LB-5277

Chittenden, Laura LB-5280

Choi, Sae Hee LB-5206

Chomean, Sirinart LB-5070

Chowdhury, Avisha LB-

5371

Chung, Amanda LB-5311

Ciota, Alexander LB-5422

Clarke, Shareese LB-5290

Clements, David LB-5425

Coello Escoto, Ana LB-5238

Colgate, E. Ross LB-5263

Colubri, Andres LB-5518

Conn, Jan LB-5006

Connelly, Sean LB-5035

Conroy, Michael LB-5336

Conteh, Solomon LB-5398

Corman, Hannah LB-5224

Coronel, Diana LB-5345

Correa, Ricardo LB-5212

Coulibaly, Drissa LB-5313

Cowles, Matthew LB-5203

Cowman, Alan LB-5130

Curran, David LB-5019

D

Dabire, Kounbobr LB-5438

Daggupati, Geervani LB-

5034

Danielyan, Ruben LB-5413

Dankwa, Selasi LB-5392

Das, Rajshree LB-5104

Dayan, Gustavo LB-5168

De, Sai Lata LB-5384

de Mast, Quirijn LB-5144,

LB-5346, LB-5472

Degarege, Abraham LB-

5468

Deichsel, Emily LB-5259

del Valle, Juana LB-5430

del Valle Vargas, Cristina

LB-5058

della Torre, Alessandra LB-

5355

DeMaso, Christina LB-5081

Denno, Donna LB-5091

Denz, Adrian LB-5406

Desewu, Kwame LB-5049

Di Santi, Silvia LB-5329,

LB-5493

Dia, Abdoulaye Kane LB-

5182

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84

Diakite, Seidina A. S. LB-

5142

Diallo, Ibrahima LB-5200

Diaz, Adrian LB-5237, LB-

5419

Diaz, Sophia LB-5504

DiazGranados, Carlos LB-

5516

Dittrich, Sabine LB-5141

Dittrich, Samantha LB-

5069

Doolan, Denise LB-5051

Doritchamou, Justin LB-

5045

Doumbia, Seydou LB-5146

Duarte, Elias LB-5496

Dube, Busisani LB-5052

Dupuis, Alan LB-5424

Durvasula, Ravi LB-5245

Dussupt, Vincent LB-5423

Dutta, Guru LB-5322

Dutta, Sheetij LB-5320

Dyall, Julie LB-5340

E

Eastman, Richard LB-5032

Eaton, Will LB-5477

Edu-Quansah, Elijah LB-

5282

Egyir, Beverly LB-5254

Ehrlich, Hanna LB-5486

Ekanem, Ekpenyong LB-

5123

Ekapirat, Nattwut LB-5506

Ekoka, Elodie LB-5178

Elliott, Richard LB-5209

Elobolobo, Eldo LB-5495

Epis, Sara LB-5189

Erice, Clara LB-5305

Ericson, Austin LB-5275

Ewald, Sarah LB-5352

Eyase, Fredrick LB-5236

F

Fagre, Anna LB-5428

Fairley, Jessica LB-5103

Farenhorst, Marit LB-5318

Fergus, Cristin LB-5446

Fernandez, Diana LB-5066

Fernandez, Lauralee LB-

5534, LB-5535

Ferreira Maia, Marta LB-

5136

Ferreira-de-Freitas, Vinicios

LB-5190, LB-5372

Fintzi, Jonathan LB-5308

Fischer, Kerstin LB-5018

Flores, Heather LB-5183

Fogang, Balotin LB-5483

Fola, Abebe LB-5395

Ford, Tristan LB-5441

Forero-Peña, David LB-

5489

Fraley, Emma LB-5060

Francis, Sheena LB-5370

Francisco, Alfredo LB-5048

G

Gallini, Julia LB-5457

Garcia-Justiniano, Jetsimary

LB-5065

Gelaw, Yalemzewod LB-

5469

Gilchrist, Carol LB-5229

Giovanni, Jennifer LB-5452

Gnankine, Olivier LB-5005

Golden, Allison LB-5285

Gomez, Doris LB-5337

Gonzales Hurtado, Patricia

LB-5205

Gonzales-Wartz, Kristina

LB-5403

Gonzalez, Luis LB-5016

Gorini, Giacomo LB-5471

Goto, Hiro LB-5510

Gray, Lyndsey LB-5012

Grunst, David LB-5439

Gueye, Alioune LB-5310

Guilaze, Rui LB-5448

Gunter, Sarah LB-5260

Gyasi, Akosua LB-5325

H

Haddow, Andrew LB-5362

Hagadorn, Kelly LB-5029

Hailemariam, Begashaw

LB-5105

Hailu, Hiwot LB-5101

Halsey, Eric LB-5134, LB-

5295

Hamza, Iqbal LB-5376

Hanpithakpong, Warunee

LB-5133

Healer, Julie LB-5039

Healy, Sara LB-5301

Helwig, Katelyn LB-5521

Hennessee, Ian LB-5474

Hess, Andrea LB-5186

Hilder, Robin LB-5246

Himes, Lauren LB-5154

Hiraoka, Tomoko LB-5094

Hiruy, Honelgn Nahusenay

LB-5127

Hixson, Bretta LB-5366

Hoar, Sandy LB-5080

Hoff, Nicole LB-5174

Hoglund, Richard LB-5139

Houston, Stan LB-5153

Howick, Virginia LB-5540

Huang, Wei-Chiao LB-5481

Hunsawong, Taweewun LB-

5239

I

Ippolito, Matthew LB-5145

Islam, Md LB-5331

Ittiprasert, Wanaporn LB-

5235

J

Jadkarim, Renad LB-5502

Jaeger, Anna LB-5356

Jahir, Tania LB-5530

Jenkins, Bethany LB-5202

Jin, Xiannu LB-5038

Johnson, Rebecca LB-5365

Joseph, Rosalia LB-5480

Joya, Christie LB-5292

K

Kajava, Andrey LB-5388

Kanai, Mariko LB-5539

Kanoi, Bernard LB-5132

Kanzok, Stefan LB-5225

Kariyawasam, Ruwandi LB-

5327

Karmen-Tuohy, Savannah

LB-5299

Karthikeyan, Arun LB-5175

Kasubi, Mabula LB-5248

Kearney, Alexis LB-5349

Kelly, John LB-5515

Kempaiah, Prakasha LB-

5497

Kern, Olivia LB-5003

Keshishyan, Ara LB-5414

Keshtkar Jahromi, Maryam

LB-5164

Khatib, Aisha LB-5436

Kim, Hyung Chul LB-5232

Kim, Ju Yeong LB-5268

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85

Kleinschmidt, Immo LB-

5300

Kline, Thomas LB-5321

Kmush, Brittany LB-5176

Koepfli, Cristian LB-5297

Koirala, Janak LB-5092

Komar, Nicholas LB-5427

Kone, Aminatou LB-5215

Kongmanas, Kessiri LB-

5063

Kont, Mara LB-5319

Krafsur, Alyssa LB-5180

Kreutzfeld, Oriana LB-5407

Kucharska, Iga LB-5382

Kulkarni, Aditi LB-5434

Kunamneni, Adinarayana

LB-5014, LB-5420

Kupritz, Jonah LB-5017

Kwan, Jennifer LB-5307

Kwizombe, Collins LB-5394

L

Lam, Aminata LB-5312

Lau, Rachel LB-5219

Lawford, Harriet LB-5046,

LB-5283

Le Rutte, Epke LB-5511

Lee, Elizabeth LB-5249

Lee, Hannah LB-5071

Lee, Ming-Chieh LB-5393

Lee, Tamsin LB-5047

Lee, Yongseok LB-5411

Leelawong, Mindy LB-5057

Leining, Lauren LB-5335

Lekagul, Angkana LB-5155

Leslie, Macall LB-5333

Li, Xue LB-5537

LI, Yiji LB-5181

Lim, Pharath LB-5303

Lindrose, Alyssa LB-5460

Liu, Jianying LB-5068

Llanos-Cuentas, Alejandro

LB-5478

Lo, Aminata LB-5210

Lochrin, Sarah LB-5271

Lopez, Anna Lena LB-5087

Lovell, Jonathan LB-5503

Low, Leanne LB-5541

Lozier, Matthew LB-5528

Lupone, Christina LB-5089

Lutwama, Julius LB-5447

M

Mabrouk, Moustafa LB-

5482

Magalhaes, Tereza LB-5520

Maganga, Jane LB-5107

Maiga, Hamma LB-5492

Maikore, Ibrahim LB-5387

Majeau, Alicia LB-5379

Major, Chelsea LB-5166

Makhani, Leila LB-5435

Malhotra, Indu LB-5100

Maloba, Franklin LB-5314

Malpass, Ashley LB-5195

Mandal, Debjani LB-5377

Manjoro, Fortunate LB-

5137

Mansuri, Saniya LB-5512

Manvell, Charlotte LB-5437

Marfin, Anthony LB-5172

Markus, Miles LB-5470

Martin, Anne LB-5484

Martin, Jackline LB-5028

Martin-Martin, Ines LB-

5002

Matowo, Johnson LB-5211

Matthews, Megan LB-5361

Matume, Nontokozo LB-

5024

Maude, Richard LB-5525

Mayor, Alfredo LB-5294

McAdam, Lorina LB-5306

McKeand, Sage LB-5412

McLeod, Brandon LB-5410

McMillan, Joseph LB-5187

McNitt, Sarah LB-5396

Mekonnen, Gebeyaw LB-

5093

Mendoza, Emelissa LB-

5163

Messa, Jr., Augusto LB-

5222

Meza, Felician LB-5124

Mhamilawa, Lwidiko LB-

5113

Milali, Masabho LB-5117

Miranda-Schaeubinger,

Monica LB-5289

Mohrien, Casey LB-5461

Molina-Cruz, Alvaro LB-

5538

Monido, Dominique LB-

5273

Montana Lopez, Julia LB-

5128

Moon, Alex LB-5440

Moon, James LB-5542

Mora-Criollo, Patricia LB-

5375

Moraes Barros, Roberto LB-

5198

Morita, Masayuki LB-5213

Morton, Lindsay LB-5152

Moscatelli, Guillermo LB-

5247

Mouline, Karine LB-5490

Mshambala, Alexia LB-5323

Mugasa, Joseph LB-5112

Mumbengegwi, Davis LB-

5129

Mura, Marie LB-5150

Musene, Kamy LB-5243

Musila, Lillian LB-5258

Musuva, Rosemary LB-

5021

Mvalo, Tisungane LB-5119

Mwema, Tabeth LB-5476

Mzilahowa, Themba LB-

5368

N

Nag, Dilip LB-5067

Nagaoka, Hikaru LB-5214

Nagarkatti, Rana LB-5288

Narayanan, Shridhar LB-

5030

Nash, Rebecca LB-5326

Nash, Scott LB-5251

Nath-Chowdhury, Milli LB-

5380

Nation, Catherine LB-5234

Ndiaye, Jean Louis LB-5487

Ndiop, Medoune LB-5309

Negrao, Fernanda LB-5508

Neira, Marco LB-5184

Ng, Justin Han Jia LB-5171

Ngai, Michelle LB-5389

Nguetse, Christian LB-5037

Ngwalangwa, Fatsani LB-

5084

Nicolas, Patricia LB-5073

Niemczura de Carvalho,

Julie LB-5459

Niemz, Angelika LB-5159

Nieto-Andrade, Benjamin

LB-5317

Njalambaha, Rukiyah LB-

5197

Norcross, Neil LB-5509

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86

Normandin, Erica LB-5162

Nsanzabana, Christian LB-

5122

O

Oberhelman, Richard LB-

5332

Oduro, George LB-5078

Ohari, Yuma LB-5233

O'Leary, Sarah LB-5011

Opi, Herbert LB-5217

Orishaba, Philip LB-5026

Otieno, Nancy LB-5466

Otto, Thomas LB-5192

Ouattara, San LB-5121

Owusu-Ofori, Alex LB-5077

P

Paige, Andrew LB-5001

Palatini, Umberto LB-5188

Pandey, Isha LB-5485

Parchment, Kimalie LB-

5369

Paronyan, Lusine LB-5415

Parpia, Tarina LB-5455

Patel, Kajal LB-5529

Patel, Shraddha LB-5088

Petersen, Jens LB-5397

Pilz, Andreas LB-5157

Pincelli, Anaclara LB-5041

Pisharody, Sruti LB-5149

Popruk, Noppon LB-5138

Pritt, Bobbi LB-5099

Prosnitz, Debra LB-5279

Purdy, Alyssa LB-5453

Purushotham, Jyothi LB-

5169

Q

Quellie, Saturday LB-5075

Quicke, Kendra LB-5013

R

Rabinovich, Lila LB-5083

Raheel, Hira LB-5338

Ramanujam, Karthikeyan

LB-5269

Ramzy, Reda LB-5102

Rangecroft, Alexa LB-5270

Rapheal, Erica LB-5278

Rathore, Abhay LB-5064

Rausch, Kelly LB-5385

Rebelo, Maria LB-5111

Reiter, Karine LB-5475

Renn, Jonathan LB-5055

Reyes, Yaoska LB-5523

Rhee, Daniel LB-5417

Ribeiro, Ana LB-5526

Robberts, Lourens LB-5074

Robertson, Molly LB-5498

Robinson, Matthew LB-

5257

Rogier, Eric LB-5304

Rollins, Randi LB-5023

Roundy, Christopher LB-

5364

Rowe, Christopher LB-5302

Ruthen, Sarah LB-5334

Rutkowski, Natalie LB-5433

S

Sa, Juliana LB-5033

Sak, Bohumil LB-5223

Salgado, Doris LB-5347

Sam-Agudu, Nadia LB-

5479

Samani, Hector LB-5531

Sanchez, Maria Carmen LB-

5328, LB-5494

Savarino, Stephen LB-5527

Schultz, Emily LB-5059

Schultz, Jonathan LB-5096

Schwake, Christopher LB-

5027

Scott, Valerie LB-5296

Seethamraju, Deepika LB-

5383

Sermé, Samuel LB-5125

Shore, Kayla LB-5524

Shrivastava, Gaurav LB-

5061

Siagian, Ria LB-5267

Sibley, Jefferson LB-5076

Siegfried, Hayden LB-5242

Sikaala, Chadwick LB-5442

Sikorski, Michael LB-5252

Silberstein, Erica LB-5373

Silva, Maria LB-5421

Silva-Caso, Wilmer LB-

5429

Simwela, Nelson LB-5199

Sinai, Cyrus LB-5462

Singh, Puspendra LB-5391

Skrip, Laura LB-5445

Smith, Michael LB-5231

Smith, Samuel LB-5053

Soares de Souza Vieira,

Thiago LB-5358

Solano, Eduardo LB-5221,

LB-5402

Soto-Hernández, Joaris LB-

5240

Spear, Joseph LB-5381

Spring, Michele LB-5500

Stanaway, Jeffrey LB-5465

Stanisic, Danielle LB-5140

Stapleton, Jack LB-5148

Stedman, Timothy LB-5367

Steinhardt, Laura LB-5491

Stephens, Haley LB-5115

Sterling, Spencer LB-5156

Stevens, Grant LB-5228

Stiffler, Deborah LB-5488

Striegel, Deborah LB-5456

Sun, Peifang LB-5519

Sutphin, Dean LB-5272

T

Takashima, Eizo LB-5196

Tan, Katherine LB-5291

Taracena, Mabel LB-5193

Taylor, Walter LB-5298

Tessema, Sofonias K LB-

5408

Thai, Elaine LB-5409

Thaisomboonsuk, Butsaya

LB-5342

Tiedje, Kathryn LB-5316

Tikhe, Chinmay LB-5008

Tina, Lucas LB-5082

Tinajeros, Freddy LB-5106

Tine, Roger LB-5109

Tolla, Habtamu LB-5265

Topazian, Hillary LB-5118

Torano, Holly LB-5404

Torrevillas, Brandi LB-5025

Tsai, Kun-Hsien LB-5363

Ty, Maureen LB-5194

U

Umaru, Farouk LB-5090

Umesumbu, Solange LB-

5330, LB-5505

V

Vajda, Elodie LB-5443

Valadares, Diogo LB-5378

Valenzuela, Paola LB-5062

Valle-Molinares, Roger LB-

5253

Vallur, Aarthy LB-5431

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Van Gordon, Mollie LB-

5454

Van Loock, Marnix LB-5350

Varadharajan Suresh,

Ragavan LB-5036

Vargas Rodriguez, Rosa Del

Carmen Miluska LB-5208

Vega, Martha LB-5348

Vega Ocasio, Denisse LB-

5284

Venkateswaran, Kodumudi

LB-5351

Victor, Kaitlin LB-5241

Vieira, Cecilia LB-5009

Vilchez, Samuel LB-5255

Volkova, Evgeniya LB-5167

W

Walker, Edward LB-5360

Wangdi, Kinley LB-5293

Warmbrod, Kelsey Lane LB-

5151

Watson, Hugh LB-5160

Weatherhead, Jill LB-5022

Weger-Lucarelli, James LB-

5354

Werkman, Marleen LB-

5020

Wiebe, Madeleine LB-5042

Wilder, Brandon LB-5507

Williams, Adeline LB-5185

Worwa, Gabriella LB-5517

Wright, Daniel LB-5158

X

Xu, Yang LB-5044

Y

Yadavalli, Raghavendra LB-

5135

Yavo, William LB-5201

Yeboah, Clara LB-5244

Yigletu, Seblewongel LB-

5464

Yousafzai, Mohammad LB-

5170

Yovo, Emmanuel LB-5450

Yukich, Joshua LB-5499

Z

Zaidi, Irfan LB-5401

Zarella, Olivia LB-5108

Zhou, Zhiyong LB-5110