LIAQUAT UNIVERSITY OF MEDICAL & HEALTH SCIENCES

JAMSHORO SINDH, PAKISTAN

ISO 9001:2008 CERTIFIED

CONTENTS

1. Message

2. Academic Calendar

3. Weekly Time Table

4. Teaching Hours

5. Departments (Faculty + Teaching Schedule)

i. Anatomy

ii. Physiology

iii. Biochemistry

6. Tagged Subjects (Teaching Schedule)

i. Community Medicine

ii. Bio Medical Ethics

iii. Behavioral Sciences

iv. Research + Applied

v. Information Technology (IT)

vi. Surgical Skills (Skill Lab)

7. Table of Specification

8. Books Recommended

MESSAGE

On behalf of the Vice Chancellor Prof. Dr. Bikha Ram Devrajani and faculty members, I welcome you all to the First Semester (First Year MBBS) class. Liaquat University of Medical and Health Sciences, is nationally and internationally recognized that distinguishes itself as the first ever public sector Medical University achieved ISO 9001:2008 certification and thus became entrenching center for outstanding teaching qualities with moral and ethical values, fantastic learning outcomes, and productivity of the student’s knowledge and experience.

We represents brilliant standards in teaching, research and creativity by regular class room activity, OSPE/OSCE pattern of evaluation, strict monitoring of student’s attendance and counseling by Director Academics to produce professionals outfitted with highest standards in transfer and application of knowledge to address the health issues of this society.

All this is only possible with support of students, their parents and teachers, which are actually the stakeholders and play fundamental role to achieve upcoming objectives and goals.

Your accomplishments at Liaquat University of Medical and Health Sciences will be the extent of our achievements in delivering high quality education, knowledge and training.

I wish you best of luck and an unforgettable learning experience during your stay at this university.

PROF SUHAIL AHMED ALMANI DIRECTOR ACADEMICS LUMHS

FIRST PROFESSIONAL MBBS ACADEMIC CALENDAR

BATCH 2019-20

Orientation Day 13th January 2020 Orientation Classes 14th &15th January 2020 Regular Classes will start from 16th January 2020 Summer Vacation + Eid-Ul-Fitr 19th April to 31st May 2020 Classes will re-start from 01st June 2020 Classes will end on 07th November 2020 Preparation leaves 09th to 29th Nov 2020 Theory + OSPE Examination 30th Nov to 12th Dec 2020 Winter Vacation 13th to 20th December 2020

THE SECOND PROFESSIONAL MBBS WILL START FROM: 21ST DECEMBER 2020

WEEKLY TIME TABLE FROM THURSDAY 16TH JANUARY 2020

TIME MONDAY TUESDAY WEDNESDAY THURSDAY FRIDAY

08:00 TO

10:00

ANATOMY Dissection &

Demonstration All Groups

ANATOMY Dissection &

Demonstration All Groups

ANATOMY Dissection &

Demonstration All Groups

ANATOMY Dissection &

Demonstration All Groups

ANATOMY Dissection &

Demonstration All Groups

10:00 TO

11:00

Biochemistry Lecture A B C

BIO LEC HALL

Anatomy Lecture A B C

ANA LEC HALL

Physiology Lecture A B C

PHY LEC HALL

Biochemistry Lecture A B C

BIO LEC HALL

Physiology Lecture A B C

PHY LEC HALL Physiology

Lecture D E F PHY LEC HALL

Physiology Lecture D E F PHY LEC HALL

Biochemistry Lecture D E F

BIO LEC HALL

Physiology Lecture D E F

PHY LEC HALL

Anatomy Lecture D E F

ANA LEC HALL

11:00 TO

01:00

PRACTICALS Physiology – A Biochemistry B Histology – C

PRACTICALS Physiology – D Biochemistry E Histology – F

PRACTICALS Physiology – F Biochemistry D Histology – E

PRACTICALS Physiology – B Biochemistry C Histology – A

PRACTICALS Physiology – E Biochemistry F Histology – D

11:00 12:00

Anatomy Lecture D E F

ANA LEC HALL

IT Lecture A B C

BIO LEC HALL

Anatomy Lecture A B C

ANA LEC HALL

Biochemistry Lecture D E F BIO LEC HALL

Community Medicine Bio Medical Ethics/

Behavioral Sciences/ Research/ Applied

Lecture A B C BIO LEC HALL

12:00 TO

01:00

Biochemistry Lecture D E F BIO LEC HALL

Physiology Lecture A B C

PHY LEC HALL

Biochemistry Lecture A B C BIO LEC HALL

Anatomy Lecture D E F

ANA LEC HALL

Anatomy Lecture A B C

ANA LEC HALL

01:00 02:00

IT-A IT Lecture D E F ANA LEC HALL

IT-E IT-C

JUMMA PRAYER BREAK

OFF

02:00 03:00

IT-B

Community Medicine Bio Medical Ethics/

Behavioral Sciences/ Research/ Applied

Lecture D E F BIO LEC HALL

IT-D IT-F

01:00 TO

03:00

PBL - D,E,F ANA (R #2) BIO (R #3)

PHYSIO (R #8) OR SKILL LAB

PBL - A,B,C ANA (R #2) BIO (R #3)

PHYSIO (R #8) OR SKILL LAB

PRACTICALS Physiology – C Biochemistry- A Histology – B

************

PBL/ SKILL LAB SCHEDULE

DATE A B C DATE D E F 21-01-2020 ANA PHY BIO 20-01-2020 ANA PHY BIO 28-01-2020 SKILL LAB ANA PHY 27-01-2020 SKILL LAB ANA PHY 04-02-2020 BIO SKILL LAB ANA 03-02-2020 BIO SKILL LAB ANA 11-02-2020 PHY BIO SKILL LAB 10-02-2020 PHY BIO SKILL LAB 18-02-2020 ANA PHY BIO 17-02-2020 ANA PHY BIO 25-02-2020 SKILL LAB ANA PHY 24-02-2020 SKILL LAB ANA PHY 03-03-2020 BIO SKILL LAB ANA 02-03-2020 BIO SKILL LAB ANA 10-03-2020 PHY BIO SKILL LAB 09-03-2020 PHY BIO SKILL LAB 17-03-2020 ANA PHY BIO 16-03-2020 ANA PHY BIO 24-03-2020 SKILL LAB ANA PHY 23-03-2020 SKILL LAB ANA PHY 31-03-2020 BIO SKILL LAB ANA 30-03-2020 BIO SKILL LAB ANA 07-04-2020 PHY BIO SKILL LAB 06-04-2020 PHY BIO SKILL LAB

14-04-2020 ANA PHY BIO 13-04-2020 ANA PHY BIO 02-06-2020 SKILL LAB ANA PHY 01-06-2020 SKILL LAB ANA PHY 09-06-2020 BIO SKILL LAB ANA 08-06-2020 BIO SKILL LAB ANA 16-06-2020 ANA PHY BIO 15-06-2020 ANA PHY BIO 23-06-2020 SKILL LAB ANA PHY 22-06-2020 SKILL LAB ANA PHY 30-06-2020 BIO SKILL LAB ANA 29-06-2020 BIO SKILL LAB ANA 07-07-2020 PHY BIO SKILL LAB 06-07-2020 PHY BIO SKILL LAB 14-07-2020 ANA PHY BIO 13-07-2020 ANA PHY BIO 21-07-2020 SKILL LAB ANA PHY 20-07-2020 SKILL LAB ANA PHY 28-07-2020 BIO SKILL LAB ANA 27-07-2020 BIO SKILL LAB ANA 04-08-2020 PHY BIO SKILL LAB 03-08-2020 PHY BIO SKILL LAB 11-08-2020 ANA PHY BIO 10-08-2020 ANA PHY BIO 18-08-2020 SKILL LAB ANA PHY 17-08-2020 SKILL LAB ANA PHY 25-08-2020 BIO SKILL LAB ANA 24-08-2020 BIO SKILL LAB ANA 01-09-2020 PHY BIO SKILL LAB 31-08-2020 PHY BIO SKILL LAB 08-09-2020 ANA PHY BIO 07-09-2020 ANA PHY BIO 15-09-2020 SKILL LAB ANA PHY 14-09-2020 SKILL LAB ANA PHY 22-09-2020 BIO SKILL LAB ANA 21-09-2020 BIO SKILL LAB ANA 29-09-2020 PHY BIO SKILL LAB 28-09-2020 PHY BIO SKILL LAB 06-10-2020 ANA PHY BIO 05-10-2020 ANA PHY BIO 13-10-2020 SKILL LAB ANA PHY 12-10-2020 SKILL LAB ANA PHY 20-10-2020 BIO SKILL LAB ANA 19-10-2020 BIO SKILL LAB ANA 27-10-2020 PHY BIO SKILL LAB 26-10-2020 PHY BIO SKILL LAB 03-11-2020 ANA PHY BIO 02-11-2020 ANA PHY BIO

DEPARTMENT OF ANATOMY S # TEACHING FACULTY

01 ASSOCIATE PROFESSOR AND CHAIRPERSON: Dr. Pushpa Goswami

ASSISTANT PROFESSORS

02 Dr. Farhana Rajpar 03 Dr. Pashmina Shaikh

LECTURERS

04 Dr. Waseemullah Shaikh 09 Dr. Muhammad Yaqoob Shahani

05 Dr. Gul 10 Dr. Umbreen Bano

06 Dr. Abdul Hadi Abbassi 11 Dr. Fahmeeda Gul Saher

07 Dr. Fouzia Shaikh 12 Dr. Sadia Effendai

08 Dr. Abdul Rauf Memon 13 Dr. Paras Surahyo

SUBJECT: ANATOMY (THREE LECTURES/ WEEK)

GENERAL ANATOMY

1 Introduction to the subject of Anatomy, different branches of Anatomy.

2 Different Anatomical Positions of human body & various imaginary planes

3 Terms of positions and movements

4 Four basic tissues of the body (epithelium, connective tissue)

5 Skin, superficial fascia & deep fascia

6 General Anatomy of bones

7 General Anatomy of cartilage

8 General Anatomy of joints with structure and classification

9 Vascular system (blood vessels & lymphatic vessels)

10 Muscular tissue

11 Nervous tissue: General introduction of nervous tissue

GENERAL EMBRYOLOGY 1 Embryology: Introduction

2 Gametogenesis: Conversion of Gem cells into Male and Female Gametes

3 1st week of development : Ovulation to Implantation

4 2nd week of development (Bilaminar germ disc)

5 Third week of development (Trilaminar germ disc)

6 Third to Eighth weeks (Embryonic Period)

7 Third month to birth: The fetus and placenta, fetal membranes

8 Birth Defects And Prenatal Diagnosis

SPECIAL EMBRYOLOGY 1 BODY CAVITIES: Formation of the intraembryonic cavity- Clinical correlates

2 Formation of diaphragm -Clinical correlates

3 DEVELOPMENT OF RESPIRATORY SYSTEM Formation of lung bud -Clinical correlates

4 larynx, trachea, bronchi

5 lungs + maturation -Clinical correlates

6 DEVELOPMENT OF CARDIOVASCULAR SYSTEM Establishment of the cardiogenic field, Formation and position of the heart tube

7 Formation of the cardiac loop, Development of the sinus venosus

8 Formation of the cardiac septa, Septum formation in the common atrium

9 Septum formation in the atrioventricular canal

10 Clinical correlates- Heart Defects

11 Septum formation in the truncus arteriosis and conus cordis

12 Septum formation in the ventricles

13 Clinical correlates- Heart Defects

14 Formation of the conduction system of the heart

15 VASCULAR DEVELOPMENT Arterial system, Aortic arches

16 Vitelline and Umbilical arteries , Coronary arteries

17 Clinical correlates- Arterial system Defects

18 VENOUS SYSTEM: Vitelline, Umbilical and Cardinal veins

19 Clinical correlates- Venous system Defects

20 CIRCULATION BEFORE AND AFTER BIRTH Fetal circulation Circulatory changes at birth

21 SKELETAL SYSTEM - Introduction Development of Skull Neurocranium

22 Viscerocranium Clinical correlates

23 Limb growth and development

24 Clinical correlates

25 Vertebrae and the vertebral column

26 Clinical correlates - Ribs and sternum

27

MUSCULAR SYSTEM - Introduction Striated Skeletal musculature Pattering of muscle Derivatives of precursor muscle cells

28 Head and limb musculature

29 Cardiac and smooth muscle

GROSS ANATOMY DEMONSTRATION/ DISSECTION CLASSES (IN GROUPS)

LOWER LIMB

1 Organization of the lower limb & pelvic girdle

2 The Front of the thigh and related parts of femur and hip bone, femoral triangle

3 The Medial compartment of the thigh and related parts of femur and hip bone, adductor canal

4 The Gluteal Region and related parts of femur and hip bone, greater and lesser sciatic foramina’s.

5 The Back of the thigh and related parts of femur and hip bone, arterial anastomosis(cruciate, trochanteric and longitudinal)

6 Popliteal fossa

7 Hip Joint

8 Introduction of the leg & foot, related parts of tibia and fibula

9 The front / extensor{Anterior} compartment of the leg (Related parts of tibia & fibula)

10 The Lateral / Peroneal compartment of the leg (Related parts of fibula)

11 The Dorsum of the foot

12 The back / flexor {Posterior} compartment of the leg (Related parts of tibia & fibula)

13 KNEE Joint

14 Articulated foot

15 Sole of the foot (Planter apponeurosis)

16 Layers of the sole of the foot

17 Proximal and distal tibiofibular joints , Ankle joint

18 Subtalar joint and other joint of the foot

19 Arches of the foot and their significance

THORAX 1 Introduction to thorax, Structure of thoracic wall

2 Sternum, costal cartilages, Ribs

3 Thoracic vertebra and related joints

4 Intercostals spaces, muscles, nerves and arteries

5 Internal thoracic artery, Thoracic Oulet syndrome & Suprapleural membrane 6 Diaphragm

7 Openings and functions of Diaphragm, the Mechanism of respiration

8 Mediastinum (Divisions)

9 Contents Of Anterior & Superior Mediastinum

10 Contents Of Posterior Mediastinum

11 Thoracic part of sympathetic trunk

12 Pleura

13 Lungs

14 Pericardium

15 Heart (overview + General Description)

16 Heart (Arterial supply + Venous Drainage) 17 Large veins of thorax, large arteries of thorax & nerve of thorax

18 Cardiac plexus UPPER LIMB

1 Introduction of Upper limb

2 Clavicle and Applied Anatomy

3 Scapula and related parts of humerus Applied Anatomy

4 Breast: Detail Description & Clinical notes

5 Pectoral Region: Skin + Muscles

6 Axilla: Walls of Axilla, Clavipectoral fascia

7 Contents of Axilla: Axillary artery, vein & Lymph nodes

8 Contents of Axilla: Brachial plexus & Clinical Notes

9 Dissection of back/ Scapular Region Skin & Muscles

10 Dissection of back/ Scapular Region Skin & Muscles

11 Muscles of Rotator cuff & Other shoulder muscles

12 Sternoclavicular & Acromioclavicular joints

13 The upper Arm (Introduction) with cutaneous supply + Superficial blood supply & Drainage & lymphatic’s

14 Humerus Bone – Applied Anatomy

15 Muscles of front of arm + its nerve supply and blood supply

16 Muscles of front of Back of arm (Neurovascular Bundles)

17 The Cubital fossa and its clinical

18 Shoulder joint and its clinical

19 Introduction of Forearm including flexor retinaculum

20 Radius Bone, interosseous membrane with clinical aspects

21 Ulna Bone with clinical aspects

22 Anterior or flexor compartment of forearm – Muscles

23 Neurovascular Bundles of anterior compartment of forearm + clinical aspects

24 Posterior compartment of forearm – Muscles, extensor retinaculum, synovial

sheath

25 Neurovascular Bundles of posterior compartment of forearm + clinical aspects

26 Elbow joint

27 Articulated Hand (bones of Hand) Wrist joint + Applied Anatomy

28 Palm of the hand Skin, Palmar aponeurosis, cutaneous supply + clinical notes

29 Small muscles of hand (Palm) - Lumbrical & interossei + Clinical notes

30 Arterial & venous supply of Palm + Lymphatic drainage

31 Nerves of palm + Applied Anatomy

32 Facial spaces of palm + Clinical notes

33 Introduction of Dorsum of hand- Skin + Dorsal venous arch + long extensor tendons(Insertion), cutaneous supply

34 Small Joints of hand and fingers, types of grips

35 Radiology + Surface Marking

HISTOLOGY PRACTICALS (IN GROUPS) TOPICS

1 Introduction + Microscope

2 Slide Preparation

3 Artifacts

4 Cell: Introduction

5 Cell Membrane

6 Cell organelles

7 Introduction of epithelial cells: Simple Epithelium

8 Stratified Epithelium

9 Membrane Specializations / Cell Junctions

10 Glandular epithelium {Exocrine glands}

11 Connective Tissue: Introduction, classification, cell and fibers

12 Connective Tissue: Ground Substance ( composition and chemistry)+ Basement Membrane

13 Muscle: Introduction + Skeletal Muscle

14 Muscle: Smooth and Cardiac Muscles

15 Bone + Cartilage

16 Structure of neuron and peripheral nerve

17 Circulatory System - Introduction – Heart

18 The Arterial system – Arteries

19 The Microcirculation - Capillaries

20 The venous system- Veins

21 Respiratory System - Introduction

22 Trachea

23 Bronchi- Primary, tertiary Bronchiole

24 Lungs- Alveoli

25 SKIN- Skin Architecture Introduction of skin & its layers

26 Epidermis, Cells of Epidermis, Dermis

27 Skin Appendages

28 Immune System- Introduction

29 Lymphoid tissue- Lymph node

30 Thymus

31 Tonsils

32 Spleen

DEPARTMENT OF PHYSIOLOGY

S # TEACHING FACULTY

01 ASSOCIATE PROFESSOR AND CHAIRPERSON : Dr. Khalida Shaikh

ASSISTANT PROFESSORS 03 Dr. Tazeen Shah

02 Dr. Rubina Ahmedani 04 Dr. Keenjhar Rani

LECTURERS 07 Dr. Urooj Bhatti

05 Dr. Fayaz Ahmed Memon 08 Dr. Hina Riaz

06 Dr. Nadeem Anwar 09 Dr. Saima Naz Shaikh

(THREE LECTURES/ WEEK) DR KHALIDA SHAIKH, DR. RUBINA AHMEDANI, DR. TAZEEN SHAH AND DR. KEENJHAR RANI

CHAPTER: INTRODUCTION TO PHYSIOLOGY & GENERAL PHYSIOLOGY

1 Functional organization of the body

2 Body Fluids (ECF & ICF)

3 Internal environment and Homeostasis

4 Control system of the body

CHAPTER: CELL 5 Introduction to human cell

6 Cell Membrane and its functions

7 Cytoplasm and its organelles I

8 Cytoplasm and its organelles II

9 Nucleus and its functions

CHAPTER: TRANSPORT ACROSS CELL MEMBRANE 10 Transport through cell membrane & its types

11 Passive transport

12 Active transport

13 Endocytosis and Exocytosis

CHAPTER: BLOOD 14 Introduction & composition of blood.

15 Functions of blood

16 Plasma Proteins and their functions

17 Morphology and functions of red blood cells (RBCs)

18 Erythropoiesis its regulation

19 Hemoglobin its synthesis and functions

20 Anemia and polycythemia

21 Types of white blood cells (WBCs)

22 Functions of WBCs

23 Monocyte-macrophage system Leukopenia & Leukemia

24 Immunity and its types: innate Immunity

25 Immunity and its types: Acquired Immunity

26 Immune tolerance and autoimmunity

27 Active and Passive Immunity and immunization

28 Allergy and hypersensitivity

29 Blood types, O-A-B

30 Rh Blood types and Erythroblastosis Fetalis

31 Transfusion Reaction

32 Platelets and their functions

33 Hemostasis, vascular spasm and platelet plug formation

34 Mechanism of blood coagulation

35 Conditions that cause Excessive bleeding in human beings

36 Thromboembolism and anticoagulants

37 Revision

CHAPTER: MEMBRANE POTENTIAL: NERVE AND MUSCLE PHYSIOLOGY

38 Resting membrane potential

39 Action potential

40 Introduction To Muscle Physiology & Types Of Muscles

41 Physiologic Anatomy of skeletal muscle

42 General & molecular Mechanism of Skeletal muscle contraction

43 Neuromuscular Junction

44 Neuromuscular Disorders (Myasthenia Gravis & rigor Mortis)

45 Introduction of the smooth muscles

46 Mechanism of action of smooth muscles

CHAPTER: CARDIOVASCULAR SYSTEM (HEART)

47 Overview of CVS

Heart valves and their functions Circulation of blood within the heart

48 Properties of cardiac muscle + vascular smooth muscle & Endothelial cells

49 Excitatory & Conductive system of the Heart

50 Effect of ANS on Excitatory Conductive system

51 Cardiac cycle I

52 Cardiac cycle II

53 Characteristics of normal ECG

54 Heart block

55 Arrhythmia

56 Regulation of heart pumping

Intrinsic regulation (Frank Starling Mechanism ) Role of ANS

57 Heart Sounds

CHAPTER: CARDIOVASCULAR SYSTEM (CIRCULATION)

58 Overview of circulation

Interrelationship among pressure , flow and resistance

59 Veins and their functions

60 Fluid Exchange at capillary level and functions of lymphatic

61 Local Control of Blood flow

62 Nervous regulation of circulation and VMC

63 Arterial pressure & regulation of arterial pressure

64 Baro-receptor feedback regulation of BP

65 Renin – Angiotensin system in regulation of BP

66 Cardiac Output

67 Venous Return

68 Physiology of Circulatory shock

CHAPTER: RESPIRATION 69 Overview of the respiratory system

70 Mechanism of pulmonary ventilation

71 Lung Compliance and Surfactant

72 Pulmonary volumes & capacities

73 Spirometery and lung function test

74 Alveolar ventilation, dead space and Minute Respiratory volume

75 Functions of respiratory passages, cough and sneeze reflexes

76 Pulmonary circulation, pulmonary edema and pleural effusion I

77 Pulmonary circulation, pulmonary edema and pleural effusion II

78 Respiratory membrane and gas exchange in the lung I

79 Respiratory membrane and gas exchange in the lung II

80 V/Q Ratio

81 Transport of oxygen in blood

82 Oxygen Hb dissociation curve

83 Transport of CO2 in blood

84 Respiratory center

85 Nervous Regulation of Respiration

86 Chemical control of respiration

87 Regulation of respiration during exercise, Periodic breathing and hering -breuer reflex

88 Respiratory changes associated with high-altitude 89 Hypoxia and oxygen therapy 90 Pathophysiology of common lung diseases I 91 Pathophysiology of common lung diseases II 92 Aviation, Space & Deep Sea Diving Physiology and Caissons Disease 93 Exercise Physiology I 94 Exercise Physiology II

PHYSIOLOGY (PRACTICALS) FACULTY FOR PRACTICALS

01 DR NADEEM ANWAR 04 DR UROOJ BHATTI 02 DR FAYAZ MEMON 05 DR SAIMA NAZ SHAIKH 03 DR HINA RIAZ 06 DR SARWAT BATOOL

LIST OF PRACTICALS 01 Introduction Of Microscope 02 Sterilization, Types And Methods 03 How To Take Venous Blood Sample 04 Introduction To Blood 05 Preparation of Blood Film And Identification Of Different Blood Cells 06 Differential Leukocyte Count (DLC) 07 Determination of Hemoglobin Percentage (HB %) 08 Determination of Erythrocyte Sedimentation Rate (ESR) 09 Determination of Blood Groups 10 Determination of Bleeding & Clotting Time (B.T & C.T) 11 Introduction to Nerve Muscle Physiology 12 Introduction to Power Lab 13 To Record The Simple Muscle Twitch (SMT) 14 To Record Phenomenon Of Muscle Fatigue 15 Nerve Conduction Velocity 16 To Record EMG In Normal Individual

17 To Record The Effect Of Respiration During Sitting, Standing And After Exercise I

18 To Record The Effect Of Respiration During Sitting, Standing And After Exercise II

19 To Record The Effect Of Respiration During Coughing And Deglutition I

20 To Record The Effect Of Respiration During Coughing And Deglutition II

21 To Record The Lung Volume And Capacities In a Normal Healthy Adults

22 To Record The Pulse Rate At Rest

23 To Record The Pulse Rate After Exercise

24 To Record The Blood Pressure of a Subject During Sitting And Standing

25 To Record The Blood Pressure Of A Subject After Exercise

26 To Record The ECG Of Person I

27 To Record The ECG Of Person II

28 To Auscultation of Heart Sound

29 CPR on Dummies

DEPARTMENT OF BIOCHEMISTRY S # TEACHING FACULTY

01 PROFESSOR AND CHAIRPERSON: Professor Dr. Shahida Hassan Memon

02 ASSOCIATE PROFESSOR: Dr. Mubeena Laghari

03 ASSISTANT PROFESSOR: Dr. Ali Raza Memon

LECTURERS

04 Dr. Bushara Jamal 08 Dr. Feriha Fatima Khidri

05 Dr. Fouzia Shaikh 09 Dr. Abdul Sattar Khan

06 Dr. Roohi Naz 10 Dr. Beenish Ghaffar Memon

07 Dr. Shakeel Ahmed Shaikh 11 Dr. Ali Karim

(THREE LECTURES/ WEEK) INTRODUCTION OF BIOCHEMISTRY

CHAPTER: BIOCHEMISTRY OF THE CELL 1 Introduction to cell (Biochemical point of view)

2 Scientific methods to study the cell biochemistry

3 Biochemical composition of the cell

CHAPTER: BIOCHEMISTRY OF THE CELL AND BODY FLUIDS 4 Ionization of water &weak acids bases

5 Concept of pH and pH scale

6 Dissociation constant & titration curve of weak acids, the concept of pK values

7 Buffers and their mechanism of action

8 Henderson-Hesselbalch Equation (No Derivation)

9 Types of particles, solution

10 Importance of selectively permeable membrane osmosis , osmotic pressure, surface tension, viscosity & their importance related to body fluids

CHAPTER: CARBOHYDRATES

11 Definition, biochemical functions and classification

12 Structure and functions of monosaccharides and their derivatives

13 Disaccharides, their important examples

14 Oligosaccharides, their combination with other macromolecules

15 Polysaccharides , their important examples and biochemical role

16 The biochemical importance of carbohydrates

CHAPTER: PROTEINS

17 Definition, Biochemical importance and classification of proteins based on Physiological properties, Functional, Nutritional and structural

18 Amino Acids, their structure, properties and functions

19 Classification and nutritional significance of amino acids

20 Dissociation, titration and importance of amino acid in pH maintenance

21 structure of Proteins and their significance

22 Separation of proteins eg: salting out, Electrophoresis, Chromatography, Centrifugation

23 Immunoglobulin’s and its biomedical significance

24 Plasma proteins and their clinical significance

CHAPTER: NUCLEOTIDE AND NUCLEIC ACIDS 25 Chemistry and structure of nucleosides and their biochemical role

26 Nucleotides, structure, their derivatives and their biochemical role

27 Synthetic derivatives of purine and pyrimidine’s their role in health and disease

28 Nucleic acid their types structure and functions

CHAPTER: LIPIDS 29 Definition biochemical function

30 Classification of Lipids

31 Phospholipids, Glycolipids, Sphingolipids and their Biochemical significance

32 Fatty Acids, Chemistry ; Classification and Biochemical function

33 (essential fatty Acids

34 Eicosanoids, their classification and function in health and disease

35 Steroids, Sterol eg: Cholesterol, their chemistry, function and clinical significance

36 Lipid peroxidation and its significance

CHAPTER: BIOLOGICAL MEMBRANE 37 Biochemical composition

38 Biochemistry of cell membrane, chemical composition, importance of lipids and proteins in membranes, chemistry of signals and receptors

39 Biochemistry of membrane transport mechanism, active transport, passive transport, simple and facilitated diffusion

CHAPTER: ENZYMES 40 Introduction, definition, mechanism of catalysis

41 Coenzymes, co-factors

42 Isoenzymes, their clinical importance

43 Factors affecting enzymes activity, Michaelis-Menten equation, Lineweaverburk equation and their application in enzyme kinetics (No derivation of equation)

44 Enzyme inhibitors and their classification & biomedical importance

45 Application of enzyme in clinical diagnosis and therapeutic use

CHAPTER: PORPHYRINS AND HEMOGLOBINS 46 Chemistry and bio synthesis of porphyrins and its disorders (porphyrias)

47 Structures, function\s and types of hemoglobin

48 Oxygen binding capacity of hemoglobin, Factors affecting and regulating the oxygen binding capacity of hemoglobin

49 Degradation of heme, Bile Pigments: Formation, Types, transport and excretion

50 Hyperbillirubinemia, their biochemical causes and differentiation, jaundice and its types

51 Haemoglobinopathies (Hb-S, thalassemia etc) and their biochemical causes

CHAPTER: VITAMINS 52 Introduction, Classification

53 Chemistry, Biochemical functions, deficiency manifestations, daily allowances and source of water and fat soluble vitamins

54 Hypervitaminosis

CHAPTER: BIOCHEMISTRY OF DIGESTIVE TRACT

55 Introduction of digestion and absorption

56 Introduction, composition, functions, daily secretion, stimulants and depressants of saliva, Gastric Juice & HCL, pancreatic Juice, Bile Juice, Succus Entericus

57 Digestion and absorption of carbohydrates, proteins, nucleic acid and lipids

58 Biochemical disorders of GIT eg: achlorhydria, peptic ulcer, lactose intolerance, cholelithiasis and related disorders

CHAPTER: MINERALS & TRACE ELEMENTS

59 Classification and Biochemical role of Macro minerals (Na, K, Ca, Cl, PO4) Micro minerals (Fe, Zn, Mg, Se, I, Cu, Cr, Cd, Mn)

BIOCHEMISTRY PRACTICALS IN GROUPS TEACHERS: ALL LECTURERS

P # TOPICS 01 General Introduction of Biochemistry and how to use Laboratory wares 02 Names of chemicals and reagents 03 Study & preparation of solution and reagents 04 Introduction of Carbohydrates 05 Detection of unknown Carbohydrates (Molisch’s test, Iodine test, Benedict’s test) 06 Detection of unknown Carbohydrates (Saliwanoff’s, Barfoed’s, and Osazone test) 07 Practical Tests of Carbohydrates 08 Introduction of Proteins 09 General tests of Protein 10 Precipitation tests of Protein 11 Separation tests of Protein 12 Practical Tests of Protein

13 Tutorial classes/ General discussion from the practical’s covered; Carbohydrate & Proteins

14 Completion of Journals 15 Practical’s Tests of whole Practical’s 16 Introduction of lipids; & it’s application in Medicine Practical point of view 17 Scheme to study the properties of lipids qualitatively 18 Practical Performance of lipids 19 Introduction of normal constituents of fasting urine 20 Introduction of abnormal constituents of urine 21 Scheme for the detection of normal constituents of urine (Demonstration) 22 Practical Performance of normal constituents of urine 23 Practical Performance of abnormal constituents of urine

24 Introduction & composition of milk, comparison of cows milk with human milk. Scheme for the analysis of milk constituents

25 Detection of carbohydrates and protein in the milk (Demonstration & Practical) Qualitatively

26 Detection of lipid and minerals in the milk (Demonstration & Practical) 27 BCQs test and practical performance test of milk 28 BCQs test and practical performance test out of whole course of practical’s 29 Getting it signed by the concerned teacher 30 Revision

TAGGED SUBJECTS SUBJECT: INFORMATION TECHNOLOGY (IT)

INCHARGE: MS. ASMA RAZA TEACHER: MR FAHEEM COMPUTER BASICS:

Introduction to Information Technology (IT) Microcomputer Advancements and Mobile Computing

COMPUTER FUNDAMENTALS Computer system & its parts

HARD WARE (COMPUTER PARTS) Central Processing Unit (CPU) Storage Memory I/ O devices

SOFTWARE Graphical User interfaces & Command line interfaces Types of Software

OPERATING SYSTEMS Essentials of Windows Operating System Working with files and folders

INTERNET AND BASIC SEARCH TECHNIQUES Internet concepts Uses of internet Search engine & Basic Search

MS- OFFICE: MS WORD MS Word screen & Tabs Text, Characters and Paragraphs Formatting pages Tables, Graphics WordArt and Charts

MS POWER POINT Working with slides Custom Animation Slide Transition Graphics Saving and Printing

INTERNET PRODUCTIVITY PACKAGE Introduction of LUMHS website Intranet & Extranet Personal E-Mail on LUMHS domain

PERSONAL ASSISTANCE PACKAGE (Google Apps & Office 365) Electronic Mail basics Calendar and scheduling Managing Contacts Tasks Instant Messaging

E - LEARNING Introduction and importance of E- Learning Introduction of Distance learning Programs

DFHC Model OCW, Coursera

SUBJECT: COMMUNITY MEDICINE (5 LECTURES) TEACHER: DR. FAIZA MEMON/ DR. ZOHEB RAFIQUE MEMON LEC. # TOPICS

1 Introduction of Community Medicine

2 Concepts of health, diseases and its dimensions

3 Health care delivery system of Pakistan

4 Fundamentals of Epidemiology

5 Introduction to IMNCI

6 Macro-nutrients ( Carbohydrates & diseases related to carbohydrates )

7 Protein Energy Malnutrition (PEM)

8 Primary Health Care

9 Introduction to Air & Ventilation

10 Air pollution & its effects on health

SUBJECT: BIOMEDICAL ETHICS TEACHER: DR ZOHEB RAFIQUE MEMON

1 Introduction to Biomedical Ethics

2 Physician- Patient Relationship

SUBJECT: BEHAVIORAL SCIENCES TEACHERS: PROF MOIN AHMED ANSARI (CHAIRMAN) / DR JAMIL JUNEJO

T O P I C S

1. What are behavioral sciences? Linking Brain, Mind and Health Care. Bio-psycho-social (BPS) model of healthcare. Use Non Pharmacological Interventions.

2. Definition of attention and concentration. Factors affecting them. Memory, stages, types & methods of improving memory. Cognition, levels of cognition. Meta cognition.

3. Principles of learning, modern methods & styles of learning, cognitive theories of learning & their use in enhancement of learning.

4. Motivation & types of motivation.

SUBJECT: RESEARCH & APPLIED (10 LECTURES / CLASSES) SUBJECT: SURGICAL SKILLS [SKILL LAB]

INCHARGE: DR ASADULLAH MAKHDOOM 1 Orientation about Skill Lab 5 Hand Washing (Scrubbing)

2 Use of Stethoscope 6 Temperature Recording

3 Peripheral Pulse Examination 7 BP Monitoring

4 Evaluation 8 Evaluation

BOOKS RECOMMENDED ANATOMY

Clinical Anatomy by Richard S Snell, Cunningham’s Manual of Anatomy Wheatears Histology, Langman’s Embryology, Keith L. Moore Embryology

PHYSIOLOGY Text Book of Physiology by Guyton & Hall, Review of Physiology by Ganong Physiology Journal For Practical

BIOCHEMISTRY Harper’s Illustrated Biochemistry. By: Robert k. Murray. Textbook of Medical Biochemistry. By: Chatterjee. Lippincott’s Illustrated Review Biochemistry. By: Champe

Textbook of Biochemistry with clinical correlations. By: Devin TM.