رسه علوی

:ساراام

:شیخ االسالهیام خاادگی

:11/07/1364تاریخ تلد

ریش هتابلیسن، داشگا علم پششکی آدرس: هزکش تحقیقات سللی هلکلی، پژشکد علم غدد درى

شید بشتی، تزاى، ایزاى

:02122432500( 420)تلفي هحل کار

:02122416264فکس

:113154763کد پستی

ایویل :@gmail.comsara.sheikholeslami, @endocrine.ac.irs.sheikholeslami

تزاى، ایزاىعلم تحقیقات، داشگا بیشیویتحصیالت: کارشاسی ارشد ،

o داشگا علم پششکی شید بشتی، تزاى، ایزاىتغذیکارشاسی ،

هزکش تحقیقات سللی هلکلی، داشجی دکتزا پژشی ، تا کى( 1312)اس سال شغل: پژشگز

ریش هتابلیسن، داشگا علم پششکی شید بشتی پژشکد علم غدد درى

هقال ای بیي ا لوللی:

International Publications:

1. Hedayati Mehdi, Zarif Yeganeh Marjan, Sheikhol Eslam Sara, Rezghi Barez Shekoufe, Hoghooghi Rad

Laleh, Azizi Fereidoun. Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma. Journal of Thyroid Research. J Thyroid Res.

2011:264248. Epub 2011 Jun 13.

2. Mahdi Rafiei, MarjanZarif Yeganeh, Sara Sheikhol Eslami, Elnaz Gozalpour, Majid Ghaffarpour, Mehdi Hedayati. Apolipoprotein E Polymorphisms Status in Iranian Patients with Multiple Sclerosis.J

Neurol Sci. 2012 Sep 15;320(1-2):22-5.

3. Asghari G, Sheikholeslami S, Mirmiran P, Chary A, Hedayati M, Shafiee A, Azizi F. Effect of

pomegranate seed oil on serum TNF-α level in dyslipidemic patients.Int J Food Sci Nutr. 2012 May; 63(3):368-71.

4. Maryam emadi, fahimeh ramezani tehrani, parichehre yaghmaei, sara sheikholeslami, Mehdi Hedayati,

Serum adiponectin levels and its association with insulin resistance and obesity in women with poly cystic ovarian syndrome, Razi journal of medical sciences, 19 (101) oct-nov 2012.

5. Sheikholeslami Sara, Zarif Yeganeh Marjan, Hoghooghi Rad Laleh, Ghadaksaz Golab Hoda, Hedayati

Mehdi. Haplotype Frequency of G691S/S904S in the RET proto-oncogene in Patients with Medullary

Thyroid Carcinoma. Iranian Journal of public health. Iranian J Publ Health, Vol. 43, No.2, Feb 2014, pp.235-240.

6. Zarif Yeganeh Marjan, Sheikholeslami Sara, Hedayati Mehdi. RET Proto Oncogene Mutation

Detection and Medullary Thyroid Carcinoma Prevention. APJCP DOI:http://dx.doi.org/10.7314/APJCP.2014.15.xx.XXXX (ACCEPTED).

7. Zarif Yeganeh Marjan, Sheikholeslami Sara, Jabar Lotfi, Samaneh Farashi, Hedayati Mehdi. Skewed

Mutational Spectrum of very Conserved RET Proto Oncogene Exon10 in Iranian patients with Medullary Thyroid Carcinoma. Tumor Biology (ACCEPTED).

8. Sheikholeslami Sara, Zarif Yeganeh Marjan, Hedayati Mehdi. A decade mutational screening of Exon

16 RET proto-oncogene mutations in Medullary Thyroid Carcinoma. Journal of Endocrine Pathology

(Submitted, under review).

هقاالت فارسی

جش . ذايتي هذي عضيضي فشيذى, حققي ساد الل, ,شیخ االسالهی سارا ظشيف يگب هشجبى, ,سصقي ببسص شکف .1

هجل پضشکي كثش تببستبى ، دس بيوبساى هبتال ب سشطبى هذالسي تيشئيذ RETپشتآکطى 11بي سايج دس اگضى

1391; 16(2:)73-78.

تغييشات پالسوبيي . هذي ذايتي، سارا شیخ االسالهی، هزجاى ظزیف یگا، هحوذ تقي خبي، جببس لطفي .2

هجل داشکذ پضشکي، . تيشييذ دس بيوبساى بب كبسسيم هذالسي استئكلسيي پشتييي شوبس چبس اتصبلي ستيل

(SCOPUS) .. 26 تب 22بي ، صفح1، شوبس 72، دس 1393داشگب علم پضشکي تشاى، فشسديي

rs1800247. پلي هسفيسن هذي ذايتي، سارا شیخ االسالهی، هشجبى ظشيف يگب، هحوذ تقي خبي، جببس لطفي .3

(، 276) 32، 1393طى استئكلسيي دس بيوبساى هبتال ب سشطبى هذالسي تيشييذ. هجل داشکذ پضشکي اصفبى،

. 1-8 بي صفح

ب دس بيوبساى هبتال G691S/S904Sذايتي. فشااي بپلتبيپ هذي يگب، ظشيف هشجبى االسالهی، شیخ سارا .4

، صفح8، شوبس 72، دس 1393، داشگب علم پضشکي تشاى، آببى هجل داشکذ پضشکيتيشييذ. هذالسي سشطبى

.532تب 526بي

اگضى قط اي بي ذايتي. جش هذي عضيضي، فشيذى ساد، حققي الل االسالهی، شیخ سارا يگب، ظشيف هشجبى .5

)پزيشفت شذ(. پضشکي كشهبى.تيشييذ. هجل علم هذالسي سشطبى ب هبتال بيوبساى دس RET پشتآکطى 11

خالص هقال کگز ای بیي الوللی هلی:

1. Sara Sheikholesmai, Golaleh Ashghari, Parvin Mirmiran.The effect of punicic acid on TNF-α in

hyperlipidemic patients. 2009, Iranian Nutrition Congress (Poster presentation)

2. Homayoun Sheikholeslami, Mahmood Gharbavi, Kamilia Kani, Sara Sheikholeslami. Trace elements

and bone mineral density in pre- and postmenopausal women. Rotterdam, The Netherlands 30April-4

May 2011 (Poster presentation)

3. Homayoun Sheikholeslami, Maryam Tofangchiha, Samaneh Rastegary, Sara Sheikholeslami.

Mandibular radiomorphometric indices as predictors of osteopenia and psteoporosis in postmenopausal

women. ECE2010, Praug, Czesh Republic (Poster presentation)

4. Hedayati Mehdi, Zarif Yeganeh Marjan, Sheikhol Eslam Sara, Rezghi Barez Shekoufe, Hoghooghi Rad

Laleh, Azizi Fereidoun.Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients

with Hereditary Medullary Thyroid Carcinoma.European Human Genetic Congress. Amesterdam RAI,

The Netherlands 28-30 May 2011 (Poster presentation, Control No. 2011-A-136-ESHG)

5. M. Rafiei, Zarif Yeganeh Marjan, S. Sheikhol Eslami, E. Gozalpour, M. Hedayati2. Apolipoprotein E

polymorphisms statues in Iranian patients with Multiple Sclerosis. European Human Genetic Congress,

Nürnberg, Germany, June 23‐26 (Poster presentation, 2012-A-430-ESHG).

6. Zarif Yeganeh Marjan, Sheikholeslami Sara, Dehbashi Golnoush, Farashi Samaneh, Hoghooghi Rad

Laleh, Hedayati Mehdi. Low Prevalence of Germline Mutations in Exons 10 and 16 of the RET proto-

oncogene among Iranian Patients with Medullary Thyroid Carcinoma. Yazd, Iran, 16-19 April 2013,

International Congress Biochemistry and molecular biology (Posterpresentation)

7. Sheikholeslami Sara, Zarif Yeganeh Marjan, Dehbashi Golnoush, Farashi Samaneh, Hoghooghi Rad

Laleh, Hedayati Mehdi. High Prevalence of haplotype frequency G691S/S904S of the RET proto-

oncogene in Iranian Patients with Medullary Thyroid Carcinoma. Yazd, Iran, 16-19 April 2013,

International Congress Biochemistry and molecular biology (Oral presentation)

8. Hedayati Mehdi, Zarif Yeganeh Marjan, Guity Kamran, Sheikholeslami Sara, Farashi Samaneh,

Hoghooghi Rad Laleh. Different Pattern of RET Exons Mutations in Iranian Patients with Hereditary

Medullary Thyroid Carcinoma. Yazd, Iran, 16-19 April 2013, International Congress Biochemistry and

molecular biology (Posterpresentation)

9. Hedayati Mehdi, Farashi Samaneh, Dehbashi Golnoush, Sheikholeslami Sara, Zarif Yeganeh Marjan,

Hoghooghi Rad Laleh. Genetic Analysis of Exons 5 and 14 of the Ret proto-oncogene in Iranian Patients

with Medullary Thyroid Carcinoma. Yazd, Iran, 16-19 April 2013, International Congress Biochemistry

and molecular biology (Posterpresentation)

10. Hedayati Mehdi, Zarif Yeganeh Marjan, Sheikholeslami Sara, Farashi Samaneh, G. Dehbashi. RET

proto oncogene Mutations in Iranian Patients affected with Medullary Thyroid Cancer. European Human

Genetic Congress. June 8‐11, Paris, France (Poster presentation, Control No. 2013-A-1937-ESHG)

11. Hedayati Mehdi, Zarif Yeganeh Marjan, Sheikholeslami Sara. Pain and Endocrine Evaluation.4th

International congress of interventional pain medicine. Oct 12-14, 2013, Tehran, Iran (Poster

Presentation).

12. Sheikholeslami Sara, Zarif Yeganeh Marjan, Hedayati Mehdi. Extended RET proto-oncogene screening

in medullary thyroid cancer. Control No. 2014-A-1819-ESHG 2014, May 31 – June 3, Milan, Italy

(publication).

13. Sheikholeslami H, Madani P, Lashkari M, Ghafelehbashi H, Ovesi S, Sheikholeslami S. Prevalence of

fibromyalgia, anxiety and depression in irritable bowel syndrome. 13th European Congress of Internal

Medicine of the European Federation of Internal Medicine (EFIM) and 82th Annual Meeting of the Swiss

Society of General Internal Medicine (SSMI), 14 – 16 May 2014,Geneva, Switzerland. (oral

peresentation)

14. Zarif Yeganeh Marjan, Sheikholeslami Sara, Hedayati Mehdi. RET proto-oncogene main exons’

mutations in Iranian patients with medullary thyroid carcinoma. Control No. 2014-A-1796-ESHG 2014,

May 31 – June 3, Milan, Italy (publication).

15. Zarif Yeganeh Marjan, Sara sheikholeslami, Fereidoun Azizi, Mehdi Hedayati. Hotspot Mutational

Spectrum of RET Proto-Oncogene in Hereditary Medullary Thyroid Carcinoma. 1st International & 13th

Iranian Genetics Congress. 24-26 May 2014. Tehran. Iran (Poster Presentation).

16. Sara sheikholeslami, Zarif Yeganeh Marjan, Fereidoun Azizi, Mehdi Hedayati. RET proto-oncogene

hotspot mutational screening among sporadic medullary thyroid carcinoma. 1st International & 13th

Iranian Genetics Congress. 24-26 May 2014. Tehran. Iran (Poster Presentation).

17. Mehdi Hedayati, Zarif Yeganeh Marjan, Sara Sheikholeslami. Mutational spectrum of RET Proto-

oncogene in Iranian Patients with Medullary Thyroid Carcinoma. ASHG 2014 Annual Meeting in San

Diego, California, October 2014, 18-22. (Poster Presentation)

18. Mehdi Hedayati, Marjan Zarif Yeganeh, Sara Sheikholeslami, Jabar Lotfi. Germline Mutational

Spectrum of RET Proto-Oncogene in Iranian Patients with Medullary Thyroid Carcinoma. 10th

International Congress of Endocrine Disorders, October 2014, 20-22 (Oral presentation).

19. Marjan Zarif Yeganeh, Jabar Lotfi, Sara Sheikholeslami, Mehdi Hedayati, Aberrant DNA Methylation

Profiles as Biomarker for Diagnosis of Thyroid Cancer Subtypes. 10th International Congress of

Endocrine Disorders, October 2014, 20-22 (Oral presentation).

20. Hoda Golab Ghadaksaz, Mahmood Dehghani Ashkezari, Laleh Hoghooghi Rad, Marjan Zarif Yeganeh,

Sara Sheikholeslami, Mehdi Hedayati. Association Study of Mutations in Exon 19 of the RET Proto-

Oncogene in an Iranian Patients with Medullary Thyroid Carcinoma. 10th International Congress of

Endocrine Disorders, October 2014, 20-22 (Poster presentation).

21. Sara Sheikholeslami, Marjan Zarif Yeganeh, Jabar Lotfi, Mehdi Hedayati. The Main Risk Factors for

Thyroid Carcinoma. 10th International Congress of Endocrine Disorders, October 2014, 20-22 (Poster

presentation).

22. Jabar Lotfi, Sara Sheikholeslami, Marjan Zarif Yeganeh, Behrouz Afarideh, Mehdi Hedayati. Insulin

Resistance and Adipokines. 10th International Congress of Endocrine Disorders, October 2014, 20-22

(Poster presentation).

23. Jabar Lotfi, Marjan Zarif yeganeh, Sara Sheikholeslami, Mehdi Hedayati. Lipoic Acid, Is an Anti-

Diabetic Vitamin?. 10th International Congress of Endocrine Disorders, October 2014, 20-22 (Poster

presentation).

استببط .، هذي ذايتيفشيذى عضيضي، ذي گالة قذكسبص، سارا شیخ االسالهی هشجبى ظشيف يگب، الل حققي ساد، .24

. چبسهيي ذ تشاىي قذ ليپي ي پش فشبسي اختالل چشبي خى: هطبلع چبقي هشكضي ب عاى عبهل پيشگيي كذ

. داشگب علم پضشکي شيذ بشتي. تشاى. ايشاى )پستش(.1392آرس 13-15كگش پيشگيشي دسهبى چبقي.

چگبلي بذى ، ذي گالة قذكسبص. د شبخصسارا شیخ االسالهی، الل حققي ساد، يگب هشجبى ظشيفهذي ذايتي، .25

13-15چبسهيي كگش پيشگيشي دسهبى چبقي. بي قلبي عشقي. يوبسي اثش صى، هعيبسبيي بشاي پيشگيي خطش ب

. داشگب علم پضشکي شيذ بشتي. تشاى. ايشاى )پستش(.1392آرس

هذي ،فشيذى عضيضي، هشجبى ظشيف يگب، ، ذي گالة قذكسبصسارا شیخ االسالهیالل حققي ساد، ،كبشي ششيفي .26

. چبسهيي بب چبقي دس جوعيت ايشاي TNF-α دس پشهتس طى G-308A G-238A بي هسفيسن استببط پلي. ذايتي

.. داشگب علم پضشکي شيذ بشتي. تشاى. ايشاى )پستش(1392آرس 13-15كگش پيشگيشي دسهبى چبقي.

فعبليت ، ذي گالة قذكسبص، هذي ذايتي.سارا شیخ االسالهی، الل حققي ساد، هشجبى ظشيف يگبپساى هخذهي، .27

. داشگب علم پضشکي 1392آرس 13-15بذي سهبي هشتبط بب چبقي. چبسهيي كگش پيشگيشي دسهبى چبقي.

شيذ بشتي. تشاى. ايشاى )پستش(.

کارگا، سوپسیم در ای آهسشی:شزکت در

1. Workshop of primary research methodology, Research Institute of Endocrine Sciences, Shahid

Beheshti University of Medical Sciences, Tehran, Iran; 2008.

2. Workshop of Advanced research methodology, Research Institute of Endocrine Sciences, Shahid

Beheshti University of Medical Sciences, Tehran, Iran; 2008.

3. Workshop of Reverse Transcription-PCR. Biological Enginering Lab, Shahid Beheshti University,

Tehran, Iran; 2010.

4. Workshop of scientific paper writing, Research Institute of Endocrine Sciences, Shahid Beheshti

University of Medical Sciences, Tehran, Iran; 2012

5. Workshop of Bioinformatics in Genetic studies, Pasteur Institute , Tehran, Iran; 2012.

6. Workshop of PROGENY program. Pasteur Institute, Tehran, Iran; 2012.

7. Workshop of Real Time PCR. Pasteur Institute, Tehran, Iran; 2013

8. Workshop of PCR Primer Design. Cellular and Molecular Endocrine Research Center, Research

Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2013.

دی ا سهی کاری:عالقو

Cancer genetics & Molecular pathway study

Epigenetics

Nutrigenetics and Nutrigenomics

Genome Wide Association Study

Bioinformatics

Population and Statistical genetics

فعالیت ا:

DNA and RNA extraction, purification

PCR techniques (RT-PCR, ARMS, Real-Time PCR)

RFLP (restriction fragment length polymorphism)

Electrophoresis techniques (Protein, DNA, and LPS)

Silver Staining Methods for Poly acryamide gel (Protein, DNA, and LPS)

Bioinformatics analysis of DNA, RNA, and Protein sequences (Blast, Alignment)

writing proposal and scientific papers