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UPCOMING EVENTS

ALUMNI WEEKEND November 3 – 5 Knoxville CAREER FAIR AND CAREER DAY November 10 and 11 Knoxville November 17 and 18 Memphis GRAND ROUNDS Thursday, November 17 12 noon (CDT)/ 1 pm (EDT)

John D. Cleary, PharmD, FCCP “Hypothesis on antimycotic pharmacology” P3 PINNING CEREMONY Friday, November 18 Memphis 46th ASHP MIDYEAR CLINICAL MEETING AND EXHIBITION New Orleans, Louisiana December 4 – 8 UT Alumni Reception at Midyear Tuesday, December 6 5:30 – 7:30 pm

TOP STORIES

Parker and Laizure Awarded NIH Grant

Robert Parker, PharmD, and S. Casey Laizure, PharmD, professors in the

Department of Clinical Pharmacy, have received a grant award of

$299,584 from the National Institute of General Medical Sciences, a

subsidiary of the National Institutes of Health. The grant will fund their

study on drug interaction.

The study, titled “Inhibition of Carboxylesterase Metabolism by

Ethanol,” focuses on identifying factors that affect the activity of

carboxylesterase enzymes, which are primarily located in the liver and

intestine. These enzymes play an important role in the metabolism of

many clinically used medications, including agents used to treat

cardiovascular disease, cancer and infectious diseases.

November 2011

To serve as a model for pharmacy education, practice, research, and outreach in Tennessee and beyond

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TOP STORIES

Parker and Laizure Awarded NIH Grant – continued

In previous laboratory studies, ethanol was identified as a potent inhibitor, suggesting that drugs metabolized by

carboxylesterase enzymes might interact with ethanol. Currently, the objective is to move these findings from the

laboratory and determine how ethanol affects the activity of carboxylesterase enzymes in humans.

The research of Drs. Parker and Laizure will compare the blood concentrations of two commonly used medications

(aspirin and Tamiflu®) that are metabolized by carboxylesterase enzymes when given alone and in combination with

ethanol.

“Given the millions of prescriptions for drugs that are metabolized by carboxylesterases and that more than 100

million people in the U.S. consume ethanol, our project may have important implications for the safe and effective use

of these drugs in patients,” said Dr. Parker. “We believe this could be a common drug interaction that has been largely

overlooked, and only by the systematic study of ethanol interaction in humans can we begin to understand the clinical

importance of this interaction. This study is the first step towards understanding this interaction in humans, and will

ultimately lead to a better appreciation of the therapeutic implications of consuming ethanol with drugs metabolized

by these enzymes.”

Gourley to Lead University of Tennessee Research Foundation

Chancellor Steve J. Schwab of the University of Tennessee Health

Science Center (UTHSC) and Marie Chisholm-Burns, PharmD, MPH,

FCCP, FASHP, newly appointed dean for the College of Pharmacy at

UTHSC, have announced that Dick Gourley, PharmD, has stepped

down as dean of the UT College of Pharmacy, in order to immediately

assume the leadership role as interim president of the University of

Tennessee Research Foundation (UTRF). UTRF is a non-profit

501(c)(3) organization that promotes the commercialization of the

University of Tennessee intellectual property. In addition, UTRF

encourages an entrepreneurial culture, contributes to state and

regional economic development, and promotes research and

education to benefit the people of Tennessee and beyond.

“Dick Gourley has contributed more than 22 years of outstanding

service to the UT College of Pharmacy,” said Chancellor Schwab. “His

many significant contributions at the Health Science Center and his

willingness to take on the challenges and opportunities at UTRF are

greatly appreciated.”

James C. Eoff, PharmD, who has been executive associate dean for the UT College of Pharmacy since 1988, has been

named interim dean for the college until Dr. Chisholm-Burns arrives on campus.

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TOP STORIES

Dean-Designate Chisholm-Burns Addresses College Family

I am honored and humbled to become the new dean of the College of Pharmacy at the

University of Tennessee Health Science Center (UTHSC). As a dynamic Health Science

Center and College of Pharmacy, with a talented support base and student body, I

wholeheartedly look forward to this opportunity.

Industrialist Henry Ford once said, “Coming together is a beginning. Keeping together is

progress. Working together is success.” Without question, the strongest asset of any

successful organization is its people. And there is no doubt that because of you –

students, alumni, faculty, staff, health care and academic partners, colleagues, and friends

– the College of Pharmacy is a thriving organization with a long-standing reputation of

quality education, service, and research. For that reason and the relentless contributions

you make to improve the profession and human condition, I hold you in the highest

esteem. As we come together for a new beginning, we must keep together and work

together to progress so our visions become reality.

We have many things to be proud of, and our future is teeming with wonderful possibilities. A few months ago, we moved

into our new building which houses offices and state of the art classrooms and laboratories that will facilitate quality

learning and scholarly endeavors. We have expanded our statewide footprint as well as our global influence, and our multi-

campus structure has allowed us to increase our capacity to carry out the college’s mission. Certainly these

accomplishments would not have been possible without teamwork, and teamwork will spur us on as we target greater

achievements in the future.

As we look toward the future and strive to make our college even better, we must keep in mind those areas of excellence

we want to build upon. We must also be cognizant of under-explored opportunities that may help lead us to higher ground.

Certainly everyone’s talents will be tapped and challenged to strengthen our quality and reputation. Working together, as a

team, we will prosper!

Our past and future successes are directly linked to the hard work of many. However, there are a few people at the

university who I want to expressly thank. The first recognition is to Dean Dick Gourley who has dedicated numerous years

and good work to the college, and we certainly extol his invaluable contributions. I would also like to thank Chancellor Steve

Schwab, Executive Vice chancellor Kennard Brown, Vice Chancellor for Finance and Operations Anthony Ferrara, and others,

including other colleges at the UTHSC, for their unwavering support of the college of Pharmacy. Additionally, I cannot

overstate my gratitude to Dr. James Eoff for his dedication to the college and for serving as interim dean until my arrival.

And a special thanks is extended to our executive team, faculty, staff, students, residents, alumni, affiliates, professional

organizations, and friends for their continued support and encouragement.

In closing, allow me to again convey my appreciation to you for the opportunity to be a part of the college’s family. I am

excited to be among the strong cast of individuals who make the college exceptional, and I will dedicate my sincerest efforts

to lead our college into the next era of growth and evolution. As we come together, keep together, and work together as a

team, I am confident that our college, and therefore its stakeholders, will reach new heights of success. I enthusiastically

look forward to meeting and working with each of you.

Marie A. Chisholm-Burns, PharmD, MPH, FCCP, FASHP

Dean-Designate, College of Pharmacy

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TOP STORIES

Boucher Honored with ACCP Clinical Practice Award

Bradley Boucher, PharmD, FCCP, BCPS, received the American College of Clinical Pharmacy’s prestigious 2011 Clinical

Practice Award. The award was presented in Pittsburgh, PA on October 16 during the Opening General Session of the

ACCP 2011 Annual Meeting.

The ACCP Clinical Practice Award honors an ACCP member who has made

substantial and outstanding contributions to clinical pharmacy practice. The

criteria considered in identifying potential candidates include exceptional

leadership in the development of innovative clinical pharmacy services and

sustained excellence in providing them. Bradley Boucher is professor of Clinical

Pharmacy and associate professor of Neurosurgery at the University of Tennessee

Health Science Center. Boucher practices in the area of Critical Care at the

Regional Medical Center at Memphis. In recommending Dr. Boucher, Dr. G.

Christopher Wood, associate professor of Clinical Pharmacy and a long-time

colleague, wrote in his letter of nomination,

“Dr. Boucher has contributed regularly to the medical and pharmacy literature

and has delivered many presentations at scientific and professional meetings focusing on critical care

pharmacotherapy and other intensive care–related subjects. As a current ACCP fellow and a past president and

treasurer of ACCP, he has provided significant leadership within the College and the profession.”

Finks, Hudson and Crill Named ACCP Fellows

AACP Fellowship is awarded in recognition of

continued excellence in clinical pharmacy

practice or research. Nominees must have been

Full Members of ACCP for at least 5 years, must

have been in practice for at least 10 years since

receipt of their highest professional pharmacy

degree and must have made a sustained

contribution to ACCP. Shannon Finks, PharmD,

BCPS; Joanna Hudson, PharmD and Cathy Crill,

PharmD, BCPS, all associate professors of

Clinical Pharmacy, were in attendance at the

2012 ACCP Annual meeting in Pittsburgh, PA to

accept this honor. Dr. Hudson was also

recently inducted into the National Kidney

Foundation as a Fellow.

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TOP STORIES

Chisholm-Burns Wins Book Award

The book, Pharmacy Management, Leadership, Marketing and Finance, authored by Marie Chisholm-Burns, PharmD, MPH, FCCP, FASHP, newly appointed dean for the College of Pharmacy, is the winner of the distinguished 2011 American Medical Writers Association (AMWA) Medical Book Award, Health Care Professionals Category. AMWA’s book awards were established more than 30 years ago to recognize the very best in fictional and non-fictional medical writing. The award was presented to Dr. Chisholm-Burns at the AMWA 71st Annual Conference on October 21 in Jacksonville, FL.

FACULTY

Agatha Nolen, PhD, FASHP (left), assistant professor of Clinical Pharmacy, graduated

from Tennessee State University on August 13, 2011 with a PhD. Her field of study was

Public Administration with research in U.S. Health Policy. Dr. Nolen’s dissertation is

titled: “Barriers to Reforming the U.S. Health Care System for Patient Safety: A Study of

Ten Years of Policy Implementation for Three Health Information Technology (HIT)

Strategies”.

Robert Parker, PharmD (right), professor of Clinical

Pharmacy, gave a presentation at the BIT Life

Sciences’ 2nd Annual International Conference of

Medichem-2011 held in Beijing, China, August 9 –

11. The theme of the conference was, Master Drug

Discovery Chemistry. The title of his presentation

was "Carboxylesterases: A New Target for Drug-

Drug Interactions?"

Emma Tillman, PharmD (left), assistant professor

for research in the Department of Clinical Pharmacy, was honored with the American

College of Clinical Pharmacy, Gastroenterology, Liver, and Nutrition Practice Research

Network Travel Award for 2011.

Susan C. Woodard, PharmD, BCPS, CGP, assistant professor of Clinical

Pharmacy, completed the ACCP Academy’s Teaching and Learning

Certificate Program.

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FACULTY

Ram Mahato, PhD, professor of Pharmaceutics and Drug Delivery, updated and revised his

book, Pharmaceutical Dosage Forms and Drug Delivery, with help from Ajit S. Narang. This

second edition incorporates pharmaceutics, drug dosage and delivery into an integrated

resource accessible to students, instructors, and professionals alike.

POSTERS AND PRESENTATIONS

In October, college faculty, students, graduate students, residents and alumni presented more than 20 posters at

national meetings of the American Association of Pharmaceutical Scientists (AAPS), American College of Clinical

Pharmacy (ACCP), Infectious Disease Society of America (IDSA) and Spanish Society of Hospital Pharmacists.

Shaun Rowe, PharmD, BCPS Megan Foster, PharmD

Sloan Regen and Jenny Easterling

Student Pharmacists

Emily McCoy, PharmD (’08)

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POSTERS AND PRESENTATIONS

Brockman M, Rowe S. Nephrotoxicity associated with weight based vancomycin dosing. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Davis WL, Greene WL, Shenep JL, Hayden RT, Triplett BM. A retrospective descriptive study of combination antifungal therapies in pediatric Hematology/Oncology patients. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Dickerson RN. Modulating the protein catabolic response to trauma and sepsis. Spanish Society of Hospital Pharmacists Pre-Conference Nutrition Symposium on Sarcopenia and Cachexia. October 18, 2011. Santiago de Compostela, Spain.

Foster ME, Cox K. Intranasal fentanyl and midazolam use in a pediatric Emergency Department. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Foster ME, Cox K. Retrospective review of NPO status in children receiving ketamine for procedural sedation in the Emergency Department. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Guarascio AJ, Slain D, Sarwari A, McKnight RL, Petros KO, Parker J, Wilson AM, Pompili M, Rinehart ML, Defazio C. A matched-controlled evaluation of an antifungal bundle in the intensive care unit at a university teaching hospital. Infectious Disease Society of America Annual Meeting. October 21, 2011 and American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Harris LE, Reaves AB, Krauss AG, Griner J, Hudson JQ. Evaluation of antibiotic prescribing patterns in patients receiving sustained low-efficiency dialysis. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

King ST, Azari L, Twilla JD, Usery JB. Analysis of outcomes and risk factors associated with extended-spectrum β-lactamase-production in bloodstream infections. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Marlowe KE, McCoy E. Pharmacists’ perceptions and knowledge regarding opioid risk evaluation and mitigation strategies (REMS) in community and ambulatory practice. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

McFarland MS, Davis KJ, Wallace JL, Morgan T, Cassidy R, Venugopal D. Utilization of home telehealth monitoring with active medication management by clinical pharmacists in veterans with type II diabetes. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

McFarland MS, Markley BM, Zhang P, and Hudson JQ. Evaluation of the MDRD and Cockroft-Gault equations for sitagliptin dosing. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Misra G, Imai H, Li X, Gardner T, Lowe T. Insulin-loaded hydrogels for treating diabetic retinopathy. American Association of Pharmaceutical Scientists. October 25, 2011. Washington, DC.

Regen SM, Motl Moroney SE, Suda KJ. Evaluation of gender equality in publishing research in pharmacy journals. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

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POSTERS AND PRESENTATIONS

Regen SM, Easterling JL, Danziger LH, Hunkler RJ, Suda KJ. A three-year analysis of antiviral prescribing trends in the United States. Infectious Disease Society of America Annual Meeting. October 21, 2011. Boston, MA.

Showkat A, Hudson JQ, Bastnagel WR. Effects of α-lipoic acid oxidative stress in ESRD patients receiving IV Iron. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Tillman EM, Helms RA, Black DD. Peroxisome proliferator-activated receptor-alpha activity is altered by omega-3 polyunsaturated long-chain fatty acids in a cholestatic liver disease model. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Tillman EM, Helms RA, Black DD. Omega-3 long-chain polyunsaturated fatty acids attenuate bile acid-induced apoptosis via Fas-dependent pathways. The American Association for the Study of Liver Diseases (AASLD) annual Liver Meeting. November 5-7, 2011.

Whaley SG, Caudle KE, Barker KS, Rogers DP. The Hsp40 co-chaperone, Jjj1, is a negative regulator of fluconazole resistance in Candida glabrata. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Woods JA, Usery JB, Self TH, Finch CK. An evaluation of the management of non-life threatening COPD exacerbations in hospitalized patients. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Woods JA, Self TH, Ray SM, Usery JB, Finch CK. An evaluation of inhaled bronchodilator therapy in patients hospitalized for non-life-threatening COPD exacerbations. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

Wu L, Zhang J, Li X, Jiang S, Lowe T. Topotecan loaded quaternary ammonium beta-cyclodextrin nanoparticles for the treatment of retinoblastoma. American Association of Pharmaceutical Scientists. October 25, 2011. Washington, DC.

Wylie D, Ray S, Rowe S, Franks A. Pharmacy student knowledge retention after completing a simulation utilizing high-fidelity mannequins compared to a written patient case. American College of Clinical Pharmacy Annual Meeting. October 19, 2011. Pittsburgh, PA.

UTCOP Fellow Selected as ACCP Best Resident and Fellow Poster

Dr. Stephanie Flowers poster titled “Sterol uptake in

Candida albicans: a novel mechanism of fluconazole

resistance” was as the American College of Clinical

Pharmacy’s (ACCP) Best Resident and Fellow Poster in

conjunction with ACCP’s 2011 Annual Meeting. The Annual

Meeting was held October 16-19, 2011, in Pittsburgh, PA.

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STUDENTS, GRAD STUDENTS & POST DOC RESIDENTS

Student Team Runner-Up at ACCP Clinical Pharmacy Challenge

A team of four UTCOP student pharmacists

competed against 84 teams initially through

four online rounds and then on to the

quarterfinal, semifinal, and final round at the

Annual ACCP Meeting in Pittsburgh, PA,

October 15-17. The team was presented with

an engraved plaque to display at the College

and $750 cash award to be shared among the

team members.

The team members are Jake Smith, Mark

Dunnenberger, Jennifer Rivers, and Sloan

Regen. This is great recognition for the UT COP

and our students and we are so proud of the

team's accomplishments.

International Students Visit UTCOP

Every fall, the college hosts a group of international students and practicing pharmacists who visit Tennessee to learn

about pharmacy practice in

the United States. This year,

students came from Ireland,

Japan, Thailand, Hungary,

and for the first time,

Turkey. The group visited

several practice sites in

Memphis and Knoxville.

Gozde Yesilyaprak, a

Master’s degree student

from Mamara University in

Turkey said, “I really enjoyed

the experience in UT, it was

great exchanging knowledge

and learning about different

applications of pharmacy

practice in the United States

as well as other foreign

countries.”

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ALUMNI & FRIENDS

Todd Burgan PharmD (‘04), won the Tennessee Golf Association (TGA) Mid-

Amateur Championship. Burgan broke numerous scoring records in capturing the

24th Annual TGA Mid-Amateur Championship presented by Gentleman Jack which

was contested at Cleveland Country Club. Burgan finished the 54-hole

championship at 203, 13-under-par.

2011 College of Pharmacy Alumni Weekend

The weekend of November 3-5 UTCOP celebrates Alumni Weekend in Knoxville.

Thursday, November 3

Fall Therapeutics Seminar Hilton Knoxville, 8 am – 5 pm

Golden Graduate, Alumni Board & Advisory Council Dinner Reception Calhoun’s on the River, 6 – 8 pm

Friday, November 4

Fall Therapeutics Seminar Hilton Knoxville, 8 am – 4:30 pm

Alumni Board & Dean’s Advisory Council Meeting Hilton Knoxville, 8 am – 12 noon

Alumni Awards and Reunion Luncheon Hilton Knoxville, 12 – 1 pm

Class Reunions Visit http://uthscalumni.com/reunions for reunion plans

Saturday, November 5

College of Pharmacy Tailgate Corner of Andy Holt and Volunteer Boulevards, 4 pm

UT vs. MTSU Neyland Stadium, 7 pm

Go to http://uthsc.edu/pharmacy/ce/ , call (800) 733-0482 or email alane@utfi.org for more information.

K-Town Throwdown Tailgate

On Saturday, October 1, UT College of

Pharmacy hosted the annual K-Town

Throwdown tailgate in Knoxville. Alumni,

students and faculty enjoyed BBQ and

festivities before UT faced off against

Buffalo.

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You Are Invited! Save the Date and join us for a UT College of Pharmacy Alumni Reception in New Orleans! The alumni reception takes place in conjunction with the ASHP 46th Midyear Clinical Meeting & Exhibition. Admission to the alumni reception is complimentary; however, advance registration is recommended for planning purposes. Please register online at uthscalumni.com/ashp by 12/1/11. We hope to see you there! For more information, contact Amanda Lane at (901) 448-8580 or alane@utfi.org. For more information about the ASHP Midyear Clinical Meeting & Exhibition, please visit www.ashp.org/midyear2011.

Save the Date

When? Tuesday, December 6 5:30 - 7:30 PM

Where? New Orleans Marriott 555 Canal Street New Orleans, LA 70130

UTHSC Alumni and Friends

62 South Dunlap, Suite 520 · Memphis, TN 38163

(901)

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OTHER

Condolences

The college family extends condolences to:

The family of Dr. Malcolm Douglas Clark of Livingston, UT College of Pharmacy Class of 1969 who passed away on September 11, at the age of 67.

It’s Football Time in Tennessee – Go Vols!

November

5 12 19 26

MTSU Arkansas Vanderbilt Kentucky

Knoxville 7 pm*

Fayetteville, AR TBA

Knoxville TBA

Lexington, KY TBA

*Alumni Tailgate on UTK campus – at corner of Andy Holt Ave and Volunteer Blvd, 4 pm

Acknowledgement

Special thanks to fourth year student pharmacist, Cyle White, for his valuable contributions to this edition of the

newsletter.

Visit our website at: www.uthsc.edu/pharmacy

The University of Tennessee College of Pharmacy

The University of Tennessee Health Science Center is an EEO/AA/Title VI/TitleIX/Section 504/ADA/ADEA employer.

Please submit news items to dbyrd4@uthsc.edu or jbogue@uthsc.edu