N,N,N',N'-Tetramethyl ethylenediamine (TEMED) · [email protected] N,N,N',N'-Tetramethyl ethylenediamine (TEMED) 1. Identification of the substance/mixture and of the company/undertaking

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N,N,N',N'-Tetramethyl ethylenediamine (TEMED)1. Identification of the substance/mixture and of the company/undertakingPreparation Name: N,N,N',N'-Tetramethyl ethylenediamine (TEMED)Product code: MB526-0010Use of the preparation: For laboratory use.Use as laboratory reagent. Company identification: Genedirex, Inc.Site: http://www.genedirex.com

2. Hazards identification2.1 Classification of the substance or mixtureClassification according to Regulation (EC) No 1272/2008Flammable liquids (Category 2), H225Skin corrosion (Category 1B), H314Acute toxicity, Inhalation (Category 4), H332Acute toxicity, Oral (Category 4), H302For the full text of the H-Statements mentioned in this Section, see Section 16.2.2 Label elementsLabelling according Regulation (EC) No 1272/2008Pictogram

Signal word DangerHazard statement(s)H225 Highly flammable liquid and vapour.H302 Harmful if swallowed.H314 Causes severe skin burns and eye damage.H332 Harmful if inhaled.Precautionary statement(s)P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking.P280 Wear protective gloves/ protective clothing/ eye protection/ faceprotection.P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Removecontact lenses, if present and easy to do. Continue rinsing.P310 Immediately call a POISON CENTER or doctor/ physician.Supplemental Hazard Statements none 2.3 Other hazards - none

3. Composition/information on ingredientsSubstancesFormula : C6H16N2Molecular weight : 116,2 g/molCAS-No. : 110-18-9EC-No. : 203-744-6Index-No. : 612-103-00-3

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We recommend handling all chemicals with caution

4. First aid measures

5. Fire-fighting measures

Skin contact Take off contaminated clothing and shoes immediately. Wash

off with soap and plenty of water. Take victim immediately to

hospital. Consult a physician.

Eye contact Rinse thoroughly with plenty of water for at least 15 minutes

and consult a physician.

Ingestion Call a doctor or poison control centre immediately. Never give

anything by mouth to an unconscious person. Do not induce

vomiting without medical advice

Inhalation If breathed in, move person into fresh air. If not breathing,

give artificial respiration. Consult a physician.

Most important

symptoms and

effects, both acute

and delayed

The most important known symptoms and effects are

described in the labelling (see section 2.2) and/or in section

11

Indication of any

immediate medical

attention and

special treatment

needed

No data available

Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or

carbon dioxide.

Special protective equipment

for firefighters

Wear self-contained breathing apparatus and protective

suit.

Special hazards arising from

the substance or mixture

Carbon oxides, Nitrogen oxides (NOx)

Advice for firefighters Wear self-contained breathing apparatus for

firefighting if necessary

Further information Use water spray to cool unopened containers.

Chemical Name CAS-No EC-No. Weight %

1,2-Bis(dimethylamino)ethane

110-18-9 ( 98-100 )

110-18-9 203-744-6 98-100

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6. Accidental release measures

7. Handling and storage

8. Exposure controls/personal protectionExposure limits 8.1 Control parametersComponents with workplace control parameters8.2 Exposure controlsAppropriate engineering controlsAvoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handlingthe product.

Personal precautions Wear respiratory protection. Avoid breathing

vapours, mist or gas. Ensure adequate ventilation.

Remove all sources of ignition. Evacuate personnel

to safe areas. Beware of vapours accumulating to

form explosive concentrations. Vapours can

accumulate in low areas. For personal protection

see section 8.

Environmental precautions Prevent further leakage or spillage if safe to do so.

Do not let product enter drains.

Methods for cleaning up Contain spillage, and then collect with an

electrically protected vacuum cleaner or by

wet-brushing and place in container for disposal

according to local regulations (see section 13).

Reference to other sections For disposal see section 13.

Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation

of vapour or mist. Keep away from sources of

ignition - No smoking.Take measures to prevent the

build up of electrostatic charge. For precautions see

section 2.2.

Conditions for safe storage,

including any

incompatibilities

Store in cool place. Keep container tightly closed in

a dry and well-ventilated place. Containers which

are opened must be carefully resealed and kept

upright to prevent leakage. Handle and store under

inert gas. Air and moisture sensitive.

Specific end use(s) Apart from the uses mentioned in section 1.2 no

other specific uses are stipulated

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Personal protective equipmentEye/face protectionTightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection-tested and approved under appropriate government standards such as NIOSH (US) or EN166(EU).Skin protectionHandle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of con-taminated gloves after use in accordance with applicable laws and good laboratory practices.Wash and dry hands.The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.Body ProtectionComplete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.Respiratory protectionWhere risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate govern-ment standards such as NIOSH (US) or CEN (EU).Control of environmental exposurePrevent further leakage or spillage if safe to do so. Do not let product enter drains

9. Physical and chemical propertiesGeneral Information

Form Form: liquid, clear Colour: colourless

Appearance No information available

Odor No information available

pH No data available

Boiling Point/Range 120 - 122 °C - lit.

Melting point/range Melting point/range: -55 °C - lit.

Flash point 20 °C - closed cup

Evaporation rate No data available

Flammability (solid, gas) No data available

Upper/lower

flammability or explosive

limits

Upper explosion limit: 9,08 %(V) Lower explosion

limit: 0,98 %(V)

Vapour pressure No data available

Vapour density No data available

Relative density 0,775 g/cm3 at 20 °C

Autoignition temperature No information available.

Oxidizing properties No information available.

Water solubility soluble

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10. Stability and reactivity

11. Toxicological informationAcute toxicity

Skin corrosion/irritation No data availableSerious eye damage/eye irritation Eyes - RabbitResult: Severe eye irritationRespiratory or skin sensitisationNo data availableGerm cell mutagenicityNo data availableCarcinogenicityIARC: No component of this product present at levels greater than or equal to 0.1% is identified asprobable, possible or confirmed human carcinogen by IARC.Reproductive toxicityNo data availableSpecific target organ toxicity - single exposureNo data availableSpecific target organ toxicity - repeated exposureNo data availableAspiration hazardNo data availableAdditional InformationRTECS: KV7175000 Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema

Stability No data available

Chemical stability Stable under recommended storage

conditions.

Possibility of hazardous reactions No data available

Conditions to avoid Heat, flames and sparks. Extremes of

temperature and direct sunlight.

Incompatible materials Strong oxidizing agents, Carbon dioxide (CO2),

Copper

Hazardous decomposition

products

Other decomposition products - No data

available In the event of fire: see section 5

Chemical Name LD50

(oral,rat/mouse)

LD50

(dermal,rat/rabbit)

LC50 (inhalation,

rat/mouse)

TEMED 268 mg/kg 5.390 mg/kg 4 h - 1318 ppm

(Rat )

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12. Ecological information

13. Disposal considerationsWaste treatment methodsProductBurn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.Contaminated packagingDispose of as unused product.

14. Transport information14.1 UN numberADR/RID: 2372 IMDG: 2372 IATA: 237214.2 UN proper shipping nameADR/RID: 1,2-DI-(DIMETHYLAMINO) ETHANEIMDG: 1,2-DI-(DIMETHYLAMINO)ETHANEIATA: 1,2-Di-(dimethylamino) ethane14.3 Transport hazard class(es)ADR/RID: 3 IMDG: 3 IATA: 314.4 Packaging groupADR/RID: II IMDG: II IATA: II14.5 Environmental hazardsADR/RID: no IMDG Marine pollutant: no IATA: no14.6 Special precautions for userNo data available

15. Regulatory informationThis safety datasheet complies with the requirements of Regulation (EC) No. 453/2010.15.1 Safety, health and environmental regulations/legislation specific for the substance or mix-ture15.2 Chemical Safety AssessmentFor this product a chemical safety assessment was not carried out

16. Other informationFull text of H-Statements referred to under sections 2 and 3.H225 Highly flammable liquid and vapour.

Ecotoxicity effects No data available

Persistence and degradability No data available

Bioaccumulative potential No data available

Mobility in soil No data available

Results of PBT and vPvB assessment PBT/vPvB assessment not available as

chemical safety assessment not

required/not conducted

Other adverse effects No data available

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H302 Harmful if swallowed.H314 Causes severe skin burns and eye damage.H332 Harmful if inhaled. This material is sold for research and development purposes only. It is not for any human or animal therapeutic or clinical diagnostic use. It is not intended for food, drug, household, agricul-tural, or cosmetic use. An individual technically qualified to handle potentially hazardous chemi-cals must supervise the use of this material.The above information was acquired by diligent search and/or investigation and the recommen-dations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may be present unknown hazards and should be used with caution. Since Genedirex, Inc. cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein.THEINFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRANTY, EXPRESS OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTCULAR PURPOSE.

For research use only. Not intended for human or animal diagnostic or therapeutic uses.

Documents

N,N,N',N'-Tetramethyl ethylenediamine (TEMED) · [email protected] N,N,N',N'-Tetramethyl ethylenediamine (TEMED) 1. Identification of the substance/mixture and of the company/undertaking