2007

Phenol ethersQ 0270 N,N-Dimethylglycine-Promoted Ullmann-Type Coupling Reactions of Aryl

Iodides with Aliphatic Alcohols. — Copper-catalyzed Ullmann-type etherification of aryl iodides with aliphatic alcohols proceeds smoothly in the presence of N,N-dimeth-ylglycine as ligand. The method is especially efficient for primary alcohols while sec-ondary cyclic alcohols are less effective. It is not suitable for aryl bromides [cf. (IV)] as well as for secondary acyclic alcohols [cf. (VIIc)]. — (ZHANG*, H.; MA, D.; CAO, W.; Synlett 2007, 2, 243-246; Dep. Chem., Shanghai Univ., Shanghai 200444, Peop. Rep. China; Eng.) — Mischke

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