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NIH-CAP Company Descriptions 2009-10 Accelerator Commercialization Track (ACT) Advanced Liquid Logic, Inc. Durham, NC Industry Sector: Diagnostics Website: http://www.liquid- logic.com Richard West CEO Tel: 919-287-9010 Email: [email protected] Advanced Liquid Logic transforms Lab-on-a-Chip from “in the Lab” to “Anywhere” rapidly advancing the “Digital Microfluidics technology”. Instead of mechanical pumps and valves, electronics are used to directly control fluid operations, enabling systems to be smaller, less expensive and more flexible than ever before. Immunoassays, PCR, clinical chemistry, sample preparation and more can be performed on the same flexible proprietary platform and chip. Assays are performed in minutes--with the sensitivity and precision of state-of-the-art laboratory instruments. A compact benchtop immunoassay analyzer has been developed and is currently being evaluated by key partners. The development of other assay formats as well as a portable analyzer is underway. Biomedica Management Corp Brooklyn, NY Industry Sector: Pharmaceuticals Website: www.biomedic.net George Falus CEO Tel: 212-719-4799 Email: [email protected] Biomedica Management Corporation is a research and development company headquartered at the SUNY Downstate Biotech Center in Brooklyn, with biochemistry labs at the UMBC TechCenter in Baltimore. The company, formed in 1999, explores and develops critical technologies in collaboration with academic scientists. The company is developing novel treatments in inflammation, sepsis, and wound healing with civilian and military applications, which address serious unmet medical needs.Its leading technology, ClotFoam, is a hemostatic agent for use in non-compressible high- volume hemorrhage with important applications in trauma, laparoscopic surgery and wound healing. Second in the pipeline is a glycolipid for the treatment of sepsis CHI Systems Incorporated Ft. Washington, PA Industry Sector: Other Website: www.chisystems.com Wayne Zachary CEO Tel: 215-542-1400 x141 Email: [email protected]

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Page 1: NIH-CAP Company Descriptions 2009-10 · Web viewXOS is the leading global provider of x-ray optics and optic-based integrated solutions for material analysis. In addition, XOS is

NIH-CAP Company Descriptions 2009-10

Accelerator Commercialization Track (ACT)

Advanced Liquid Logic, Inc.Durham, NCIndustry Sector: DiagnosticsWebsite: http://www.liquid-logic.com

Richard WestCEOTel: 919-287-9010Email: [email protected]

Advanced Liquid Logic transforms Lab-on-a-Chip from “in the Lab” to “Anywhere” rapidly advancing the “Digital Microfluidics technology”. Instead of mechanical pumps and valves, electronics are used to directly control fluid operations, enabling systems to be smaller, less expensive and more flexible than ever before. Immunoassays, PCR, clinical chemistry, sample preparation and more can be performed on the same flexible proprietary platform and chip. Assays are performed in minutes--with the sensitivity and precision of state-of-the-art laboratory instruments. A compact benchtop immunoassay analyzer has been developed and is currently being evaluated by key partners. The development of other assay formats as well as a portable analyzer is underway.

Biomedica Management CorpBrooklyn, NYIndustry Sector: PharmaceuticalsWebsite: www.biomedic.net

George FalusCEOTel: 212-719-4799Email: [email protected]

Biomedica Management Corporation is a research and development company headquartered at the SUNY Downstate Biotech Center in Brooklyn, with biochemistry labs at the UMBC TechCenter in Baltimore. The company, formed in 1999, explores and develops critical technologies in collaboration with academic scientists. The company is developing novel treatments in inflammation, sepsis, and wound healing with civilian and military applications, which address serious unmet medical needs.Its leading technology, ClotFoam, is a hemostatic agent for use in non-compressible high-volume hemorrhage with important applications in trauma, laparoscopic surgery and wound healing. Second in the pipeline is a glycolipid for the treatment of sepsis

CHI Systems IncorporatedFt. Washington, PAIndustry Sector: OtherWebsite: www.chisystems.com

Wayne ZacharyCEOTel: 215-542-1400 x141Email: [email protected]

CHI Systems creates decision-support and training systems that are usable, intuitive, and effective for individuals and the organizations in which they work. We apply our proprietary computational models of human cognition, personality, and emotion to build virtual environments in which decision makers can learn and practice complex clinical, teamwork and communication skills. Our medical simulation product TEACH, for example, helps clinicians develop and hone culturally appropriate communications skills for patient communication in oncology. In TEACH, clinicians interact with virtual standardized patients, each distinct cultural backgrounds and individual personalities, in realistic clinical encounters and receive customized coaching and feedback.

CFD Research CorporationHuntsville, AL

Ashok SinghalCEO

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Industry Sector: Research ToolWebsite: www.cfdrc.com

Tel: 256-726-4829Email: [email protected]

CFDRC specializes in engineering simulations and innovative designs for Aerospace, Defense, Biomedical and Energy applications. Using our software and experimental facilities, we develop new hardware concepts, innovative designs, and prototypes. The Biomedical Technology branch of CFDRC develops innovative products and solutions for critical needs such as: (a) Microfluidics and nanotechnology for environmental, biological and clinical diagnostics, (b) Integrative bioinformatics and systems biology software tools for personalized healthcare, and (c) Micropower technologies for sensors and implantable medical devices.

Boston Micromachines CorporationCambridge, MAIndustry Sector: Medical DevicesWebsite: www.bostonmicromachines.com

Paul BierdenCEOTel: 617-688-4178Email: [email protected]

Boston Micromachines Corporation (BMC) is the leading provider of advanced microelectromechanical systems (MEMS)-based mirror products used in commercial adaptive optics systems. By applying wavefront correction to produce high resolution images, BMC devices can be used for imaging biological tissue and the human retina and to enhance images blurred by the earth's atmosphere. The company's suite of award-winning compact DM products is the most cost-effective, highest performance mirrors in the market. They are widely used to drive scientific discovery in microscopy, astronomy, and vision science. Customers include NASA, UC Berkeley, Lockheed Martin and Boston University. BMC also offers custom-designed manufacturing services.

Conversion Energy Enterprises, Inc.Spring Valley, NYIndustry Sector: PharmaceuticalsWebsite: conversionenergy.com

Barbara SoltzCEOTel: 845-425-9170Email: [email protected]

CEE is an innovation-driven, medical technology company, developing specialty surgical devices and biologics. Its mission is to provide systems to the medical community based on proprietary laser technology and light activated biomaterials.

New Health Sciences incBethesda, MDIndustry Sector: Medical DevicesWebsite: www.newhealthsciences.com

Martin CannonCEOTel: 240-475-0181Email: [email protected]

NHSi is developing and commercializing technologies in to two intereralted categories -- hemodynamic products and hematology products. The hemodynamic products include: hemodynamic vascular analysis (HVA) a method on analysing doppler data to assess the health of blood vessels in the brain; webTCD an method of managing transCranial Doppler data more efficiently; and sonAP, a non-invasive and precise measure of ABP. Hematology products include HASP an anaerobic blood storage device the extends the shelf life of stored RBC's and improves their therapeutic quality and MCA which measures the deformability and other therapeurtically relevant propoerties of stored RBC's.

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Orthogen, LLCSpringfield, NJIndustry Sector: Medical DevicesWebsite: www.orthogencorp.com

Harold AlexanderCEOTel: 973-467-2404Email: [email protected]

Orthogen LLC was spun off from its corporate parent, BioLok International, Inc, in October 2007. As a BioLok division, Orthogen previously developed the LaserLok ™ line of dental implants and calcium sulfate-based bone graft materials. The new company retains intellectual property rights for new generations of bone graft products, bioreactors, "smart" transcutaneous prostheses, orthopedic implants, cardiac stents and intraocular lenses. Orthogen is currently researching and scaling up these technologies. In the near term, Orthogen LLC is developing and marketing a new line of completely resorbable synthetic bone graft products for dental applications trade- named DentoGen™. Presently, Orthogen is clinically testing a novel, patented nanocomposite bone graft material, DentoGen-CR, that undergoes controlled degradation in the body and stimulates bone regeneration as it degrades. This nanocomposite, allowed for marketing by US FDA, will be launched in the fourth quarter of 2009. A first generation bone graft material, DentoGen™, was launched in 2008.

OsteoGeneX IncKansas city, KSIndustry Sector: PharmaceuticalsWebsite: www.osteogenex.com

Debra ElliesCEOTel: 816-509-6510Email: [email protected]

We develop phamaceuticals which build new bone for treatment of osteoporosis, spinal fusion, or fracture repair.

Quintessence Biosciences, Inc.Madison, WIIndustry Sector: BiotechnologyWebsite: www.quintbio.com

Laura E. Strong, Ph.D.President and Chief Operating OfficerTel: 608-441-2950Email: [email protected]

Quintessence Biosciences is a private, clinical stage biopharmaceutical company developing novel, proprietary, anti-cancer compounds based on its EVade™ ribonuclease technology platform. Quintessence’s first product candidate, QBI- 139, is in a Phase I clinical trial at the University of Wisconsin Comprehensive Cancer Center. The company also has a pipeline of other EVade™ Ribonuclease products in preclinical research. The company is currently working to generate financial support to fund the next stage of clinical development of QBI-139 and further the development of other compounds in the pipeline.

Resodyn CorporationButte, MTIndustry Sector: BiotechnologyWebsite: www.resodyn.com

Larry FarrarCEOTel: 406-497-5252Email: [email protected]

Resodyn Corporation's vision is to be a recognized, world-class leader in providing innovative technical solutions. Our passion for technology and commitment to progress is conveyed in our mission statement, Building Value through Discovery and Innovation®. In addition to our established Business Units, Resodyn Corporation is continuing to develop other advanced technology and products based upon our core technologies in the areas of Mixing Technology , Separations Technology , Cell-Culturing Reactors , Tissue Engineering , Thermal Processing Technologies and Processing Technologies for Renewable Resources

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Robin Medical, Inc.Baltimore, MDIndustry Sector: Medical DevicesWebsite: www.robinmedical.com

Erez NevoCEOTel: 443-450-4030Email: [email protected]

Robin Medical is a medical technology incubator company founded in 1997 by physicians and engineers from the Johns Hopkins Hospital in Baltimore, Maryland. Our main focus is in the field of MR-guided interventions. Our primary product, the EndoScout® tracking system enables navigation of devices to their target under realtime MRI. It was developed during the years 2001-2004 with SBIR grant support and it is FDA-cleared to guide any surgical intervention. It is used for clinical and research applications in 12 leading clinical centers in the USA, Japan and Europe. Our mission is to provide the required tools to transform MRI from almost pure diagnostic modality into a commonly used interventional tool.

St Charles PharmaceuticalsNew Orleans, LAIndustry Sector: PharmaceuticalsWebsite: www.stcharlespharma.com

Kenneth NarducyCEOTel: 408-219-8748Email: [email protected]

St Charles Pharmaceuticals (SCP) is developing a series of first-in-class analgesics. The Company’s first compound (oral SCP-1) is in Phase I human studies for acute pain. In 2008, the Company was awarded a 3-year $3 million NIH grant to fund the preclinical development of its second compound, SCP-123, for neuropathic pain. The first year of that grant was recently completed, resulting in the demonstration of oral efficacy in neuropathic pain models and safety in in vitro assays. SCP will next conduct the in vivo safety studies through CROs and subsequently prepare and submit the SCP-123 IND to the FDA.

SureGene, LLCLouisville, KYIndustry Sector: DiagnosticsWebsite: http://www.suregene.net/home.aspx

Mike BurkeCEOTel: 847-687-3873Email: [email protected]

SureGene, LLC utilizes modern genetic technology to discover the underlying genetic basis for psychiatric diseases. Our primary goal is to empower patients and physicians with knowledge to make the best possible healthcare decisions based on individual genetic profiles. SureGene, LLC will accomplish these goals through DNA-based diagnostic tests that predict drug response and aid in the diagnosis and classification of disease, such as the AssureGeneTM Test for Schizophrenia. As never before possible, this personalized approach to medicine should provide new options and increase the confidence and comfort level for patients, their families, and health care providers.

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Swaasth IncOklahoma City, OKIndustry Sector: OtherWebsite: http://www.swaasth.com/

Rama RamanujamCEOTel: 405-297-8881Email: [email protected]

Swaasth Inc, provides high quality, cost-effective disease preventive dietary botanical agents. This is accompanied with gene-expression based quality assurance testing. The company plans to provide pharmaceutical and Ayurvedic preparations, natural product medicines, derived from plant, animal and microbial material. The company is prepared to provide alternative-medicine services of ‘structure-function’ assays, in vitro studies, in vivo studies, clinical trials, and drug design and testing. Strategically, without educated consumption of fruits, vegetables and spices and regular exercise, one would be at a serious disadvantage in dealing with diseases. National surveys indicate that more than half of adults in the United States take some form of dietary supplement. Botanical components comprise about 25 percent of the supplement market. These products are used by consumers to promote health and wellness, prevent and treat disease. Despite widespread use of dietary supplements with botanical components and promising science, quality assurance in this area has been relatively limited and unfocused. As a consequence, efficacy and safety of many widely used botanical components have not been adequately evaluated. The intense confusion of health benefits of foods and natural supplements requires constant quality assurance based on scientific analysis. Only rigorous scientific evaluation of botanicals will drive real growth and renewal of an enterprise. Swaasth Inc. will serve academic commercial and government clients to develop dietary botanical supplements based on gene expression quality testing.

Xcision Medical Systems LLCClarkesville, MDIndustry Sector: Medical DevicesWebsite: NA

Christopher AmiesCEOTel: 443-982-5560Email: [email protected]

Our Company manufactures radiotherapy systems specifically created and optimized for treating early stage breast cancer. Our unique technology provides a new high quality treatment option that is effective, safe and convenient. Gamma Pod treatment is non invasive and reduces 7 weeks of treatment to as little as 3 visits to the clinic. This provides greater access for women to choose a path to breast conservation.

Tensegrity ProstheticsLouisville, COIndustry Sector: Medical DevicesWebsite: www.tenspro.com

Jerome RifkinCEOTel: 303-547-5738Email: [email protected]

Tensegrity Prosthetics, has created the first major non-robotic advance in prosthetic foot design in the past 25 years with a product that emulates the actions of the natural foot in walking. Tensegrity’s foot allows functional efficiencies that will enable many more lower limb amputees to enjoy more stability and freedom of mobility. This prosthesis gives them the opportunity to participate in more activities because it allows wearers to do more without tiring, compared to other prosthetic foot designs currently on the market. Tensegrity will succeed by creating win-win relationships throughout the value chain.

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Vital AccessWest Valley City, UTIndustry Sector: Medical DevicesWebsite: www.vital-access.com

Doug SmithCEOTel: 801-443-9390Email: [email protected]

Vital Access is a medical device developer working to improve vascular access methods for patients, doctors, and nurses. Vital Access has developed a subcutaneous vascular access aid that is placed directly on a patient’s vasculature through novel and proprietary surgical and interventional methods. The subcutaneous vascular access aid will enable safer and more reliable chronic access, while reducing the occurrence of infections and other serious complications that require hospital referral. Hemodialysis access, drug delivery access for oncology, aquapheresis access, and general vascular access may all benefit from this advancement.

X-Ray Optical Systems, Inc.East Greenbush, NYIndustry Sector: Research ToolWebsite: www.xos.com

David GibsonCEOTel: 518-880-1500Email: [email protected]

XOS is the leading global provider of x-ray optics and optic-based integrated solutions for material analysis. In addition, XOS is the market leader in providing fully intergrated solutions for the petroleum industry with its Sindie and Clora detectors which identify low concertratins of these elements in petroleum products including diesel, gasoline, biofuels, and crude.

Zacharon Pharmaceuticals, Inc.San Diego, CAIndustry Sector: PharmaceuticalsWebsite: zacharon.com

Robin JackmanCEOTel: 858-768-7828Email: [email protected]

Zacharon is developing drugs that target glycans; a class of molecules with key roles in cancer and other diseases. Despite extensive evidence that glycans are excellent drug targets, few companies have successfully targeted glycans due to lack of effective preclinical drug discovery tools. Zacharon has overcome this challenge by creating proprietary assays for high-throughput screening of glycan targeted small molecule drugs, leaving an exceptional opportunity for a new class of therapeutics with little competition. This platform is being leveraged across a variety of cancers and other diseases, allowing the company to generate a portfolio of drug candidates. Zacharon intends to advance the drugs through Phase I clinical trials and then attract larger companies for advanced trials and marketing.

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Commercialization Training Track (CTT)

Acelot, Inc.Santa Barbara, CAIndustry Sector: PharmaceuticalsWebsite: http://acelot.com/

Ambuj SinghCEOTel: 805-617-3610Email: [email protected]

Acelot develops software for graph synthesis, querying, and mining with immediate applications to drug discovery. The combination of proven graph-based technology for mining data with flexible information integration and knowledge management will improve the efficiency of drug discovery pipelines in the pharmaceutical industry.

ADA Technologies, Inc.Littleton, COIndustry Sector: Research ToolWebsite: adatech.com

Clifton BrownCEOTel: 303-874-8264Email: [email protected]

ADA Technologies is a technology development and commercialization company. ADA commercializes technology in a number of different technical and market areas. This program is focused on the development of carbohydrate microarray slides, microarrays, services, and supporting products. ADA has been in business for 25 years and has spun out five companies and more than seven license agreements.

Adarza BioSystems Inc.West Henrietta, NYIndustry Sector: DiagnosticsWebsite: www.adarzabio.com

Randolph HenkeCEOTel: 585-214-2406Email: [email protected]

ADARZA BIOSYSTEMS is an early stage medical diagnostics company developing a rapid and label-free biological assay platform for measuring clinical and point-of-care (POC) samples. Adarza’s proprietary chip-based platform, Arrayed Imaging Reflectometry (AIR), achieves high sensitivity by detecting intensity changes in images of antireflective chips functionalized with highly specific detection molecules (proteins, DNA, etc.). The AIR platform can perform sophisticated clinical tests within minutes and is a label free, fully arrayable technology that will potentially allow hundreds of tests to be run simultaneously on a single chip using a single sample.

Advanced Hearing ConceptsBodega Bay, CAIndustry Sector: OtherWebsite: na

Harry LevittCEOTel: 707-875-2289Email: [email protected]

Company serves as a consultant to the Hearing Industry and Academia, and develops new technologies for hearing rehabilitation.

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Aerodyne Research, Inc.Billerica, MAIndustry Sector: Medical DevicesWebsite: www.aerodyne.com

Charles KolbCEOTel: 978-663-9500 ext. 290Email: [email protected]

Aerodyne Research, Inc. has provided R&D services and products to commercial and government clients working to solve national and international problems since 1970. Areas of specialization include atmospheric research using advanced environmental monitoring instrumentation, remote sensing and image processing, novel energy sources, and computer modeling and simulation. Our breath analysis system for the study of respiratory diseases builds on our expertise in developing sensitive trace gas monitors. Over the past 8 years, Aerodyne has focused on developing commercial products and services from proprietary technologies. Product sales now account for 45% of revenue. Total company revenue and distribution is given below.

AerophaseLongmont, COIndustry Sector: PharmaceuticalsWebsite: www.aerophase.com

Brian HansenCEOTel: 303-651-1791Email: [email protected]

Aerophase, Inc. is a small research and development company that was founded in 1997 by Brian N. Hansen, PhD. The focus of the company is the development of drug delivery technologies that utilize supercritical fluid carbon dioxide as a process fluid. The overall strategy is to develop new drug aerosol systems, improve existing ones, reduce costs, and replace solvents and fluids that are hazardous to health and the environment. Aerophase has made significant strides towards developing a new, proprietary drug and device combination for the treatment of lung cancer with inhaled paclitaxel.

Akina, Inc.West Lafayette, INIndustry Sector: Medical DevicesWebsite: http://www.akinainc.com/index.html

Kinam ParkCEOTel: 765-464-0390Email: [email protected]

Akina, Inc. has been operating since 2001 and has two primary fields of technology. One technology is drug delivery systems (rapidly dissolving tablets (Frosta) and nano/micro particles made by nano/micro fabrication, and the other is biomedical implantable devices based on biodegradable polymers.

APC Biotechnology ServicesRockville, MDIndustry Sector: BiotechnologyWebsite: www.apcbio.com

Aprile PilonCEOTel: 301-452-2899Email: [email protected]

APC Biotechnology Services (The Company) is a small, closely held start up located in Rockville, Maryland. The Company seeks to commercialize a proprietary technology platform for the rapid, scalable and economical production of long peptides and small proteins. This market is currently served through chemical synthesis, a process that is inefficient, costly and technically challenging for peptides longer than 20 amino acids. Our process is based on recombinant techniques and a unique combination of a stable carrier protein and high fidelity protease that permits the robust production of peptides of any length in bacteria.

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Attotron BiotechnologiesCarson City, NVIndustry Sector: OtherWebsite: cybertory.com

Robert HortonCEOTel: 415-332-6864Email: [email protected]

The Cybertory Virtual Molecular Biology Laboratory is an on-line educational platform for teaching techniques and fundamental concepts of molecular biology, molecular genetics, and bioinformatics. The software supports a wide range of simulation-based problem solving exercises that can be targeted to different learners. Our open-source website (cybertory.org) hosts an assortment of example exercises, including paternity testing, forensic identification, and DNA sequencing, that have already been used around the world. We are developing commercial services at cybertory.com that will make it easier to use these teaching materials in undergraduate college and university courses.

Berkeley Analytics, Inc (DBA NutritionQuest)Berkeley, CAIndustry Sector: OtherWebsite: www.nutritionquest.com

Torin BlockCEOTel: 510-704-8514Email: [email protected]

NutritionQuest, a privately held company in Berkeley, California, provides affordable wellness programs for employee and membership groups. The NutritionQuest ALIVE program -- A Lifestyle Intervention via Email -- is an individually-tailored diet and physical activity behavior change program. Alive has been tested in a large randomized controlled trial and was found to significantly improve diet and physical activity behaviors. The company is also one of the nation’s leading providers of assessment measures for diet and physical activity. They are the sole source of the widely used Block Food Frequency questionnaire.

BioFormatix, Inc.San Diego, CAIndustry Sector: DiagnosticsWebsite: www.bioformatix.com

Dariusz WroblewskiCEOTel: 858-248-2884Email: [email protected]

BioFormatix, Inc. is a research, product development, and service company focusing on the needs of biomedical markets. Our technology addresses complex problems in data collection, processing and modeling. The current product development programs include: (1) Portable, head mounted perimeter (apparatus for visual field testing) funded by National Eye Institute, and (2) Algorithms for analysis of microarray gene expression data funded by National Institute of General Medical Sciences. Our VFExpert™ product, a diagnostic aid software for early detection of glaucoma based on the results of the visual field test, has been licensed for implementation in a line of Oculus (Germany) perimeters. 

Bio-Quick CorporationSilver Spring, MDIndustry Sector: Medical Devices

Wei-Sing ChuCEOTel: 301-625-8102

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Website: www.bio-quick.com Email: [email protected]

Bio-Quick Corporation is a start-up company developing pathology instruments and assays, founded in 1999 in Silver Spring, Maryland. Bio-Quick's proprietary technologies include the ultrasound-facilitated tissue preservation technology, apparatus and methods for efficient processing of biological samples on slides, and devices and methods for on-slide biomolecule extraction. These innovative technologies, invented by Dr. Wei-Sing Chu, founder of Bio-Quick, have been patented, and Bio-Quick has exclusive license for the rights to commercialize these technologies. Bio-Quick™ R&D and business activities aim at significantly improving the speed, cost-effectiveness, and efficiency of pathological research and cancer diagnosis.

Bioscience Development IncNew York, NYIndustry Sector: DiagnosticsWebsite: biosciencedevelopment.com

Steven SchutzerCEOTel: 212-452-1731Email: [email protected]

Identification of specific targets or biomarkers of a disease and translation into an immunobased assay or process

Brown and Herbranson Imaging, Inc.Portola Valley, CAIndustry Sector: OtherWebsite: www.ehuman.com

Bruce FogelCEOTel: 650-823-2137Email: [email protected]

Brown and Herbranson Imaging, Inc. (B&H), with research facilities at Stanford University and offices in Cupertino, CA, develop educational software centered on high resolution CT scanned 3-D interactive images of human anatomy. Designed primarily for the dental market, B&H develops atlases of the human dentition, of dental occlusion and mastication and of head and neck anatomy. Through support from NIH grants, B&H is expanding into areas of dental school curriculum development and human anatomy resources for the medical community.

Bruce Technologies Inc.Chapel Hill, NCIndustry Sector: Medical DevicesWebsite: brucetech-targets.com (under construction)

Bruce WielandCEOTel: 919-933-1831Email: [email protected]

Bruce Technologies is a privately held S-Corp that develops, manufactures, and sells high performance cyclotron targets to maximize production of fluorine-18 and other radiopharmaceuticals used in clinical PET/CT. Metabolic imaging applications of PET/CT include diagnosis and therapy evaluation of cancers, Alzeimers, cardiac, bone, and additional major diseases. Commercial retrofit target products introduced in mid 2008 are now in use on cyclotrons that include the GE PETtrace, Siemens RDS-111, and Cyclopharma Laboratories (France) 14 MeV. Our products are based on patented target inventions (USPTO and foreign) reduced to practice with NIH SBIR projects funded in 2004-2008. A grant application for NIH RFA-OD-09-008 BRDG-SPAN was submitted 9-01-09 to request R&D support to achieve full commercialization by 4-1-2013. Our cyclotron target retrofit technology significantly outperforms OEM systems, driving an increased volume of radiopharmaceutical doses sold by our customers through lower costs, more efficient scheduling, and increased reliability. Company goals

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beyond expanded retrofit sales include licensing products to cyclotron manufacturers, and negotiating equity in new centralized cyclotron radiopharmacies based on a unique business model enabled by our technology.

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Culmini Inc.Burlingame, CAIndustry Sector: Healthcare ITWebsite: www.culmini.com (company) and www.pickcare.com (product under development-username&password available upon request)

Constantia PetrouCEOTel: 650-504-6716Email: [email protected]

Culmini helps patients and their families with what to do to get the successful treatment their doctor recommended.  Our web tools provide step-by-step actions and support to doctor-patient conversations grounded in treatment success facts and hospital success comparisons. 

Dynaflow, Inc.Jessup, MDIndustry Sector: OtherWebsite: www.dynaflow-inc.com

Georges ChahineCEOTel: 301-604-3688Email: [email protected]

Dynaflow, Inc.® provides quality research and development services and products in fluid dynamics and material science. As a leader in the fields of gas/liquid interface dynamics, bubble dynamics and cavitation, fluid structure interaction, erosion dynamics, we offer services and products for the naval and marine, automotive, energy, chemical, environmental and food and agriculture industries. We pursue an inter-disciplinary approach to problems and have strategic collaboration with federal laboratories, commercial industries and universities.

Eon CorpDavis, CAIndustry Sector: Research ToolWebsite: www.eonresearch.com

Owen HughesCEOTel: 530756-6903Email: [email protected]

Eon is developing environmental toxicity testing solutions. The importance of protecting our environment and reducing exposure to environmental toxins is well recognized. Current toxicity identification and characterization technologies are expensive, yet deliver little or very narrow and focused information. Eon has taken the toxicity testing technologies developed in the pharmaceutical industry and is developing an environmental toxicity testing infrastructure that will quickly and inexpensively provide a wealth of actionable information for the identification and characterization of environmental toxins.

FFA Sciences LLCSan Diego, CAIndustry Sector: DiagnosticsWebsite: www.ffasciences.com

Alan KleinfeldCEOTel: 858-455-3776Email: [email protected]

FFA Sciences is developing non-invasive diagnostics for human disease. The company has developed a technology platform to produce highly specific molecular probes for unbound metabolites (Metu) in blood. The unbound Metu pattern generated by a particular disease provides a highly sensitive and specific diagnosis of the disease. The technology uses only a drop of blood and is complete within seconds. FFA is developing tests for cardiovascular ischemia (the largest cause of death in first world countries), hyperbilirubinemia / jaundice (potentially dangerous condition in newborns) and fatty liver disease; one of the fastest growing diseases in the U.S.

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FocalCool LLCMullica Hill, NJIndustry Sector: Medical DevicesWebsite: focalcool.com

Thomas MerrillCEOTel: 856-256-4301Email: [email protected]

FocalCool seeks to develop technologies that use therapeutic hypothermia to protect organs. We are currently developing a guide catheter to be used in cardiac catheterizations that maintain the functionality of existing guides while also providing rapid localized cooling to tissue at risk. Our local cooling device, called CoolGuide, can cool tissue much faster than total body cooling devices and avoids the detrimental effects of systemic cooling methods.

GeneCopoeia, Inc.Rockville, MDIndustry Sector: BiotechnologyWebsite: www.genecopoeia.com

Sun LuCEOTel: 301-762-0888Email:

GeneCopoeia, Inc. (GCI) is a biotechnology start-up company specialized in genomic-scale gene expression vector construction, gene expression, and protein expression/purification. The company has developed a unique, proprietary technology for refolding proteins expressed in E. coli as inclusion bodies. GCI utilizes its refolding technology to refold/purify proteins expressed as inclusion bodies in E. coli for developing important drug targets and protein drugs. GCI has developed a healthy protein drug pipeline such as the recombinant p53-fusion protein for cancer currently funded by a SBIR Phase II, and a mini-Plasmin protein for thromboembolic diseases currently funded by a SBIR Phase I.

GENOFi LLCSan Clemente, CAIndustry Sector: Research ToolWebsite: www.genofi.com

Jean-Michel LeliasCEOTel: 949-547-7737Email: [email protected]

Genofi creates research tools to accelerate the discovery of novel gene transcripts and to elucidate the molecular basis of the human transcriptome. We specialize in high-quality cDNA library products that are specifically designed to increase full-length representation of the longest expressed sequences while capturing the highest diversity of each mRNA source. Our technologies are focused on the discovery of alternative splice isoforms and mutant transcripts, since we believe that gene variants will be essential in the comprehensive analysis of protein function and expression studies.

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I.D.E.A.S., Inc.Kirtland, OHIndustry Sector: OtherWebsite: www.ideasconsultinginc.com

Margaret CalkinsCEOTel: 440-256-1880Email: [email protected]

I.D.E.A.S., Inc. is a research and consulting group that helps long term care providers-nursing homes, assisted living, retirement communities, home health agencies, the staff who work and residents who live in these settings-create more resident-centered, resident-directed settings. I.D.E.A.S., Inc has developed several website resources, online courses and products for professionals and elders who want to maximize the effectiveness of their physical environment.

InFlame TherapeuticsHouston, TXIndustry Sector: PharmaceuticalsWebsite: inflame.biz

Laura JacobusCEOTel: 609-799-8221Email: [email protected]

development of markers and drugs for treatment of brain inflammation as found in Alzheimer's disease and HIV dementia

InterScience, Inc.Troy, NYIndustry Sector: Medical DevicesWebsite: http://www.intersci.com

James WooCEOTel: 518-283-7500 ext. 11Email: [email protected]

InterScience, Inc. is a contract research and development company dedicated to the advancement of technology through the application of knowledge with imagination. InterScience thrives on the challenge of niche market technology development for customers in commercial industry, federal and state government. At present, InterScience is developing a distal tip endoscope, utilizing state-of-the-art imaging sensors and illumination technology, integrated with InterScience’s C-View optics to provide the clinician with an ultra-wide field of view. In the practice of minimally invasive surgery and diagnostics this capability is unattainable by present day endoscopes.

inXsol, LLCPhoenix, AZIndustry Sector: OtherWebsite: www.inxsol.com

Henry RyngCEOTel: 602-347-9575Email: [email protected]

inXsol, LLC is a Phoenix-based simulation and eLearning development company with over 11 years experience creating and implementing solutions for our customers' mission-critical training needs. inXsol serves the aerospace, education, industrial, financial services and medical markets and has many very familiar Fortune 500 clients. inXsol has seven employees and supplements these employees will a robust pool of associates who are engaged for specific projects or when their industry-specific expertise is needed. Henry Ryng, inXsol’s founder and CEO, has nearly 25 years experience in training and simulation development.

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ISCHEM CorporationLa Jolla, CAIndustry Sector: DiagnosticsWebsite: www.ischemcorp.com

Joel HuizengaCEOTel: 858-459-0011Email: [email protected]

ACUTE PREVENTION OF HEART ATTACK AND STROKE The problem: Cardiovascular disease is hailed as the leading cause of death and disability in the developed world. Over 70% of heart attacks and strokes are caused by so-called “vulnerable” coronary and carotid plaque that is not detectable by current diagnostic methods. Plaque is material that occludes arteries and reduces lifegiving blood flow to tissue. However heart attacks and strokes are commonly not caused by plaques that occlude the highest percentage of flow. Most typically they are caused by vulnerable plaque, plaque that has characteristics that make it liable to rupture and produce a clot. Such plaque has characteristic features, including a thin fibrous cap, a large lipid pool, and abundant macrophages. If such plaques could be detected noninvasively, and treated prior to rupture, a major advance in healthcare would be achieved. The solution: The noninvasive detection of vulnerable plaque, plaque that is at high risk of provoking a heart attack or stroke, represents a crucial step in preventing cardiovascular events. Recent advances from ISCHEM’s technologies have created the possibility for detection and treatment of the cause of vascular events that previously did not exist, based on an advanced suite of patented pattern recognition tools applied to noninvasive magnetic resonance imaging (MRI) data. ISCHEM is able to detect the vulnerable plaque and its location noninvasively. Our patented technology is able to relocate the same plaque locus after presumptive treatment, to permit qualitative and quantitative determination of the success of a therapy or intervention. The ability to provide a therapy/outcome loop enables optimization of therapy for individual patients. (It further enables improvement of treatment approaches over time, enabling comparison of candidate treatment in the research setting, and fostering development of more effective treatment modalities.)

KeraMed Inc.Sunnyvale, CAIndustry Sector: Medical DevicesWebsite: keramed.com

Yichieh ShiueyCEOTel: 408-887-4856Email: [email protected]

KeraMed Inc. is a medical device company that specializes in the development of surgical devices and implants for the cornea. These products have applications for both the treatment of disease as well as for the correction of vision errors such as nearsightedness, farsightedness and astigmatism.

Looking Glass AnalyticsOlympia, WAIndustry Sector: OtherWebsite: www.lgan.com

Joe KabelCEOTel: 360-570-7531Email: [email protected]

Looking Glass Analytics is a Software-as-a-Service (SaaS) provider, delivering web-accessible, enterprise-wide tools for data collection, data analysis, reporting and mapping. We provide these services to a variety of human services organizations including public health, criminal justice, social services and education. Our mission is to help clients transform their data into useful information and streamline access and delivery to people who need it.

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LucigenMiddleton, WIIndustry Sector: BiotechnologyWebsite: www.lucigen.com

David MeadCEOTel: 608-831-9011Email: [email protected]

Lucigen develops advanced products for molecular biology and the life sciences.

MAX mobilityAntioch, TNIndustry Sector: Medical DevicesWebsite: www.max-mobility.com

Mark RichterCEOTel: 615-731-1860Email: [email protected]

MAX mobility develops cutting edge assistive technology for persons with mobility impairments. Our products include the FlexRim ergonomic pushrim, OptiPush propulsion training device, SitKit wheelchair fitting system and PushOn wheelchair accessible treadmill.

MD Informatics, LLCSalt Lake City, UTIndustry Sector: Healthcare ITWebsite: www.mdinformatics.com

Terry ClarkCEOTel: 435-602-9767Email: [email protected]

MD Informatics, LLC (MDI) is a veteran-owned, physician-led medical information technology firm based in Salt Lake City, Utah, USA. MDI's core competencies include medicine, surgery, nutrition, and physical therapy combined with expertise in systems/Web/database design, structured data collection, Web development, and eLearning technology research and development. MDI's physician informaticists provide consulting services to government agencies and private healthcare organizations. MDI also runs an eLearning division responsible for the R&D of innovative online instructional methods, leading to products that have commercial potential, including a case-based virtual patient platform as well as full courses addressing a variety of medical topics.

MediSpin Inc.new York, NYIndustry Sector: Healthcare ITWebsite: http://medispin.com/

Brian ShanahanCEOTel: 212-255-9948Email: [email protected]

MediSpin inc. is an innovative medical communications company, established as an S-Corporation in June 1999. MediSpin is a community of knowledgeable, experienced, creative professionals dedicated to meeting the marketing, training, and educational needs of diverse healthcare and pharmaceutical specialists worldwide. Combining our thorough understanding of health and medical issues with our expertise in multimedia technology, MediSpin specializes in the design, development, and delivery of teaching and learning programs that engage, educate and extract information from your targeted audience. Since 2003, MediSpin has been awarded several NIH SBIR contracts and 1 grant with combined funding exceeding $6 million.

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Metabolic NutritionalsPortland, ORIndustry Sector: [email protected]: http://metabolicnutritionals.com/

Neil BuistCEOTel: 503-705-3089Email: [email protected]

The company was started to receive royality income. Funds are used to pay for research activities in academic institutions specifically Oregon Health & Sciences University. The income relates to patents developed for products used in the treatment of inborn errors of metabolism. The expenditures have been used to support an independant 501c Foundation [Oregon Metabolic Disease Foundation] for projects related to laboratory tests and treatment of inborn errors of metabolism and current activities relating to quantification of infant nutrititive sucking.

MetaMedia Training International, Inc.Germantown, MDIndustry Sector: Healthcare ITWebsite: www.metamediausa.com

Thomas HeldCEOTel: 301-515-6300 ext. 202Email: [email protected]

MetaMedia Training International specializes in the design and production of custom interactive training programs. We feature in-house graphics production, video/audio editing, and multimedia authoring studios. Our instructional designers have developed thousands of hours of curricula for a diverse spectrum of applications. MetaMedia is a pioneer in developing state-of-the-art, technology-based training solutions. Platforms and applications include: eLearning, mLearning (mobile learning), Interactive DVD, Instructor-led training, HD video, Interactive kiosks, exhibits, and touch screen systems. MetaMedia established a subsidiary, MetaMedia Publishing, to commercialize and distribute interactive training products, some of which have been developed with SBIR funds.

MicroFab Technologies, Inc.Plano, TXIndustry Sector: Research ToolWebsite: www.microfab.com

Donald HayesCEOTel: 972-578-8076Email: [email protected]

MicroFab develops and commercializes new technology aimed at enabling high-payoff applications for microdispensing and precision printing in a wide range of industries and applications. Commercial and industrial applications of the technology include microdispensing of liquid solder; adhesives; optical and electrical polymers; and biomedical materials, including diagnostic reagents. The speed, precision, and digital nature of ink-jet printing technology makes it well suited for automated control in the manufacturing plant or research laboratory.

MicroProbes for Life ScienceGaithersburg, MDIndustry Sector: Research ToolWebsite: www.microprobes.com

Martin BakCEOTel: 301-330-9788Email: [email protected]

MicroProbes for Life Science, an ISO 9001:2000 registered firm, is a leading provider of implantable neural microelectrodes, multi-channel arrays, and related systems. With over 25 years of experience in microelectrode design and fabrication, the company leverages its expertise to provide unparalleled technical support and customization for any application. MicroProbes for Life Science boasts an extensive list of satisfied customers, ranging from university-affiliated and independent research facilities to Fortune 500 pharmaceutical and medical device companies.

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MMJ Labs LLCAtlanta, GAIndustry Sector: Medical DevicesWebsite: http://www.needle-pain-management.com/

Amy BaxterCEOTel: 404-371-1190Email: [email protected]

Our company's mission is to promote personal pain control using reusable hospital-based and OTC products. Our main technology, Buzzy, combines vibration and cold to relieve sharp pain on contact. It is the least expensive needle-pain option, and more effective than the leading immediate acting competitor for IV access pain.  Buzzy has applications for dental shots, home IM injections, and cosmetic procedural pain, and is game-changing in being available directly to patients.  Flippits! distraction cards can enhance procedural pain relief.

Myomics, Inc.Providence, RIIndustry Sector: Research ToolWebsite: www.myomics.com

Herman VandenburghCEOTel: 401-226-1252Email: [email protected]

Myomics™ mission is to discover and develop new therapeutics for improving muscle function. Using its novel tissue engineered muscle-based drug screening technology, Myomics can rapidly and accurately discover and develop new drugs to be used to improve skeletal muscle performance as well as to attenuate skeletal muscle dysfunction in disorders such as sarcopenia, cancer cachexia, and the muscular dystrophies. Contract drug screening is performed for the pharmaceutical industry while in-house efforts are focused on discovering and developing therapeutics for Duchenne's Muscular Dystrophy, an orphan disease for which the estimated US market potential is $1 billion.

Neurobiotex, Inc.Galveston, TXIndustry Sector: Medical DevicesWebsite: http://neurobiotex.com

Christopher FredericksonCEOTel: 409-762-0678Email: [email protected]

Zinc Based Diagnostics and Research Tools - We will provide medical devices for the early and accurate diagnosis of Prostate Cancer. We are in the pre FDA refinement portion of our clinical study as guided by our FDA meeting in December of 2008.

Northwest Media, IncEugene, OR

Lee WhiteCEO

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Industry Sector: OtherWebsite: www.northwestmedia.com ; www.fosterparentcollege.com ; www.vstreet.com ; www.sociallearning.com

Tel: 541-343-6636Email: [email protected]

Northwest Media, Inc. produces and markets high quality, innovative social learning products designed to serve the community of at-risk youth, their parents, and social service providers. We have narrowed our company objectives to three: to provide state-of-the-art quality training materials; to apply innovative technology to improve social services; and to market social learning products effectively. The company has created and oversees three distinct websites: 1) FosterParentCollege.com offers self-driven web based training courses for foster, adoptive and kinship parents; 2) SocialLearning.com, an on-line marketplace for social learning books, DVDs and CDs from Northwest Media and select vendors; and 3) VStreet.com, a comprehensive life skills website with full-length curricula, e-zines, artistic and social features, designed to help teens develop the skills and attitudes it takes to make it on their own.

PharmaIN, Corp.Seattle, WAIndustry Sector: PharmaceuticalsWebsite: www.pharmain.com

John PresuttiCEOTel: 871-991-5961Email: [email protected]

PharmaIN, Corp. licensed the Protected Graft Copolymer (PGC) technology from Harvard-MGH as an injectable drug delivery platform. This platform is a chemical polymer drug carrier which binds non-covalently to a drug payload to increase blood circulation time without modification of the chemical structure of the drug. PGC is most suitably used as a carrier for peptides and small proteins, although studies with larger (>100 kDa) proteins are underway. Other benefits include; increased solubility, passive targeting of solid tumors and infected/inflamed tissue, easy manfacturing, multiple administration routes, and stable formulation profiles.

Pressure BioSciences, Inc.South Easton, MAIndustry Sector: Research ToolWebsite: www.pressurebiosciences.com

Richard SchumacherCEOTel: 508-230-1828 ext. 131Email: [email protected]

Pressure BioSciences, Inc. is a life sciences company focused on the development and commercializatoin of a novel, enabling platform technology called pressure cycling technology (PCT).

QCMetrix, Inc.Waltham, MAIndustry Sector: Healthcare ITWebsite: www.qcmetrix.com

Majed TomehCEOTel: 781-290-5900Email: [email protected]

QCMetrix is the exclusive provider of information technology and program management services for the American College of Surgeons National Surgical Quality Improvement Program. QCMetrix has developed a suite of Web-based technologies to systematically collect, analyze, and present meaningful clinical data relating to surgery. The company has a software development staff and a staff of experienced surgical nursing staff, all of whom help medical centers across the U.S. and a few international hopitals make sense of their healthcare data to make real differences in surgical outcomes and costs. QCMetrix also serves the Michigan Surgical Quality Collaborative, a program funded by BCBS of Michigan at 33 surgical centers. Similarly, QCMetrix also serves the Tennessee Surgical

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Quality Collaborative.

Recombinant Technologiescheshire, CTIndustry Sector: PharmaceuticalsWebsite: www.recombtech.com

Pazhani SundaramCEOTel: 203-271-3125Email: [email protected]

The company is involved in R & D of therapies to Alzheimer's Disease for 7 years and has identified small molecules very effective in treating Alzheimer's Disease by binding to the causative factor, namely, ABeta peptides. Intellectual property is being protected by the company [Patent pending with USPTO]. Preliminary data obtained through in vitro and in vivo studies are very encouraging. The proposed small molecule treatment reduces brain plaques and improves memory parameters in AD model mice. Additional studies are required to test pharmaco kinetic and toxicoligical parameters. In addition, studies to dissect the mechanism of clearance of the drug and the bound target molecules are required.

ReprogeneticsLivingston, NJIndustry Sector: DiagnosticsWebsite: www.reprogenetics.com

Santiago MunneCEOTel: 646-207-2897Email: [email protected]

Reprogenetics is a company specialized in genetic testing for reproductive purposes. It is the leader in Preimplantation Genetic Diagnosis (PGD) in the US, diagnosing embryos or gametes. Our future plans involve entering the pre-conception diagnosis market for infertile couples, to better determine causes of infertility and risks of conceiving an abnormal child, and means to act upon that information, by using SNP arrays and other upcoming technologies. Being a small company, we have focused on targeting infertility center as our clients, but we would like to start targeting the ultimate costumer for our services, which is the infertile couple.

Samuels & AssociatesOakland, CAIndustry Sector: OtherWebsite: http://www.samuelsandassociates.com

Sarah SamuelsCEOTel: 510-271-6799Email: [email protected]

Created in 1994 by Dr. Sarah Samuels, Samuels & Associates, Inc. (S&A) is a consulting firm specializing in research, evaluation, policy analysis, strategic planning and program development. Staff members are experienced in a wide variety of research methodologies, including developing qualitative and quantitative instruments, data collection, database management, and analysis. S&A’s expertise is in ensuring full participation of all stakeholders in program and evaluation design and in interpretation of research and evaluation findings. The goal of the firm is to further client priorities by developing tools and reports that can be used by programs for replication, monitoring, or disseminating accomplishments.

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Santech, Inc.La Jolla, CAIndustry Sector: OtherWebsite: www.santechhealth.com

Sheri ThompsonVP Business DevelopmentTel: 858-453-4948Email: [email protected]

Santech, Inc. utilizes wireless, mobile (text messaging) and web-based technologies, credible clinical trials testing, and multi-disciplinary expertise to provide innovative and effective diet, physical activity and other health-related behavior change programs and tools for consumers, behavioral health researchers and clinicians.

Senex Biotechnology, Inc.Albany, NYIndustry Sector: PharmaceuticalsWebsite: www.senexbio.com

Lawrence FriedhoffCEOTel: 201-425-1913Email: [email protected]

Senex Biotechnology has a proprietary screening system for identifying small molecule drugs for the treatment of diseases associated with aging. Its primary focus is on cancer where we have identified a specific transcriptional pathway and molecular target activated in many intractable cancers that can be blocked by a new class of compounds discovered by our company. These compounds have anti-tumor activity in vivo. In addition, we have identified a separate class of compounds that have an anti-cancer activity in vitro, due to their ability to inhibit the production of tumor-promoting factors by cancer-associated fibroblasts, a unique mechanism of action. The latter compounds also have transcriptional effects that may be beneficial for Alzheimer's Disease.

SimQuestSilver Spring, MDIndustry Sector: Healthcare ITWebsite: www.simquest.com

Howard ChampionCEOTel: 410-626-0322Email: [email protected]

SimQuest unifies cutting-edge expertise from multiple disciplines to create technology-assisted simulators for surgical training. Technology to be commercialized is a surgical simulator for teaching open-access surgical skills.

Source Production & Equipment Co., Inc.St. Rose, LAIndustry Sector: Medical DevicesWebsite: www.spec150.com

Kevin J. SchehrVice PresidentTel: 504-464-9471Email: [email protected]

SPEC is a 35 year-old, privately-owned company, dedicated to designing and manufacturing high quality and high safety radioactive sources, shielded devices and equipment including radiotherapeutic medical devices. SPEC has expanded its portfolio to include sources for temporary high dose rate (HDR) brachytherapy. The Lung Staple was the first project to receive funding from NIH/NCI. SPEC subsequently received funding for the development of an HDR brachytherapy system for treatment of eye cancer using the radionuclide 169Ytterbium. SPEC’s manufacturing facilities, material control, inspection, and a modern radioisotope laboratory licensed by the State of Louisiana are located in two

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9,000 square foot facilities.

Strategic Polymer Sciences, Inc.State College, PAIndustry Sector: Medical DevicesWebsite: http://strategicpolymers.com

Ralph RussoCEOTel: 814-238-7400Email: [email protected]

Strategic Polymer Sciences, Inc. (SPS) was founded in 2006 to commercialize electro-active polymer (EAP) technology exclusively licensed from The Pennsylvania State University. The mission of SPS is to create enabling technologies to improve the quality of living in the medical device, military, transportation, electronics, and energy industries.  The SPS polymer film technology provides a distinct advantage in energy density, size and weight over traditional polypropylene and electrolytic capacitors. With packaged energy densities of up to 5 times higher than competitive technologies, SPS capacitors can deliver more capacitance and energy for reduced volume and weight or higher energy storage and capacitance in the same volume.  These characteristics make polymer capacitors ideal for medical defibrillator and military and commercial pulsed power applications.  In addition, SPS EAP materials exhibit large electromechanical response for high performance polymer actuators.  Their very high strain (3-5%) and modulus (0.2-1.0 GPa) make them ideal for novel device applications such as electrically steerable catheter tips and force sensors, laparoscopic and minimally invasive surgical tools, deformable and steerable mirrors, pumps, and energy harvesters.

TechnoVax, Inc.Tarrytown, NYIndustry Sector: BiotechnologyWebsite: www.technovax.com

Jose M. GalarzaCEOTel: 914-345-2300 ext. 11Email: [email protected]

TechnoVax is a biotech company with a main focus in vaccine development. The company uses its unique proprietary virus-like particles (VLPs) technology to produce mass markets vaccine for infectious diseases such as influenza, respiratory infections and disorders as cancer. Pre-clinical tests have demonstrated complete efficacy against several flu viruses. TechnoVax's technology offers important advantages over current vaccine creation and production methods. These include faster production times, safer and controllable process, products of higher valency (single VLP include two or more antigens) and yield ratios, and lower overall cost. All these have the potential to significant change the creation and production of vaccines. The worldwide market for vaccines is more than $10 billion…and growing.

Transcendent International LLC (dba LanguageMate)New York, NYIndustry Sector: Healthcare ITWebsite: www.languagemate.com

William Z. TanCEOTel: 212-274-1654Email: [email protected]

At LanguageMate, we develop innovative solutions to bridge the language gap in healthcare. Persons with limited English proficiency (LEP) are among the most vulnerable of the country’s population and

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face significant barriers to obtaining adequate care at medical facilities; they are more likely than others to defer essential medical care, leave a clinic without adequate medical advice, and miss follow-up appointments. Enabling healthcare providers to communicate with LEP patients in a linguistically competent and culturally sensitive manner is at the core of our mission.

Vida Health Communications, Inc.Cambridge, MAIndustry Sector: OtherWebsite: www.vida-health.com

Lisa McElaneyCEOTel: 617-864-4334Email: [email protected]

Vida Health Communications, Inc. is dedicated to improving the health of women, children and families through the production of evidence-based educational media for clinical, patient and lay audiences. Vida’s holistic approach develops solutions that deliver consistent messages to both providers and their patients around important health topics. Recent Phase II funding was used to develop a training curriculum for neonatal caregivers and families for supporting the development of preterm infants in the NICU. Another Phase II grant developed a training curriculum on managing environmental health risks in pregnancy for obstetric providers and their patients. As a result of these and other ongoing Phase II projects Vida has developed a proprietary web-based platform for authoring and deploying multimedia e-learning content.

VisionQuest Biomedical, LLCAlbuquerque, NMIndustry Sector: BiotechnologyWebsite: www.visionquest-bio.com

Peter SolizCEOTel: 505-228-3875Email: [email protected]

VisionQuest's business strategy is to use the SBIR/STTR program to fund promising ideas in medical imaging devices and computer-aided diagnostics. We are developing optical devices for ophthalmology and automated systems for screening broad segments of the population for eye diseases. We have patented the image processing technology for eye disease screening and are poised within the next year to 18 months to secure private investment capital to enter into a commercial phase.

Wave 80 BiosciencesSan Francisco, CAIndustry Sector: DiagnosticsWebsite: www.wave80.com

Daniel LaserCEOTel: 415-859-1959Email: [email protected]

Wave 80 Biosciences is an early-stage biotechnology company focused on developing, manufacturing, marketing, and selling innovative molecular diagnostics instruments and consumables for infectious disease, cancer, and other human health conditions.  Wave 80's pipeline molecular diagnostics products address major unmet needs of patient populations in the U.S., Europe, and Japan, as well as in emerging economies such as China and Brazil.

Women Insight, Inc.Milton, MA

Tara CousineauCEO

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Industry Sector: Healthcare ITWebsite: www.bodimojo.com

Tel: 617-333-0441Email: [email protected]

Women Insight, Inc .is a health communications consulting firm and geared to launch it's flagship product, www.BodiMojo.com, an on line health destination and personalized health platform for teenagers.

Xhale, Inc.Gainesville, FLIndustry Sector: Medical DevicesWebsite: www.xhale.com

Richard AllenCEOTel: 352-371-8488Email: [email protected]

Xhale, Inc. is a a research and development company focusing on breath-based diagnostics and novel vapor technology. We have several products in development including SMART™ (Self-Monitoring and Reporting Therapeutics) devices and drugs to improve medication adherence and drug level monitoring aand HyGreen, a hand hygiene system.

Zumatek Inc.Chapel Hill, NCIndustry Sector: Medical DevicesWebsite: www.zumatek.com

Randolph McKinleyCEOTel: 919-225-3965Email: [email protected]

Zumatek was formed by researchers at Duke University Medical Center, in an effort to bring to commercialization the dedicated breast imaging technologies for 3D lesion detection developed at Duke. Zumatek incorporated in 2005 with the objective to develop imaging technologies able to detect breast cancer at earlier stages and more sensitively and specifically than traditional X-ray mammography, leading to improved survival and reduced morbidity. The company is in the R&D and early commercialization stage with its first Phase II SBIR award geared toward a next generation clinic-ready breast CT scanner and planned patient trials.  Other products in the pipeline include dedicated dual modality breast SPECT-CT and PET-CT.