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October 29-31, 2018 San Raffaele Congress Centre, Milano NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER 3 rd Annual Meeting Organized in collaboration with SCIENTIFIC PROGRAM www.alleanzacontroilcancro.it/3rd-annual-meeting-of-alliance-against-cancer-milan

NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

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Page 1: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

October 29-31, 2018San Raffaele Congress Centre, Milano

NEWTECHNOLOGIESAND STRATEGIES TO FIGHT CANCER3rd Annual Meeting

Organized in collaboration with

S C I E N T I F I C P R O G R A M

www.alleanzacontroilcancro.it/3rd-annual-meeting-of-alliance-against-cancer-milan

Page 2: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

Under the auspices of

Public Affairs - Alliance Against CancerGuido Schwarz - [email protected]

Scientific SecretariatManuela Sovilla - [email protected]

Local Scientific CommitteeFabio Ciceri, Paolo Dellabona, Vanesa Gregorc, Vincenzo Russo, Giovanni TononI.R.C.C.S. Ospedale San Raffaele, Milano, IT

Scientific CommitteeRuggero De Maria, RomaPier Giuseppe Pelicci, MilanoGennaro Ciliberto, RomaPaolo De Paoli, Roma

Alessandra Bearz, Aviano (PN)Gerardo Botti, NapoliAngelo P. Dei Tos, TrevisoClaudio Doglioni, MilanoVirginia Ferraresi, RomaDiana Giannarelli, RomaLuca Gianni, MilanoMassimo Guidoboni, Meldola (FC)Roberta Maestro, Aviano (PN)Giuseppe Opocher, Padova

Roberto Orecchia, MilanoFrancesco Perrone, NapoliPiero Picci, BolognaConcetta Quintarelli, RomaPaolo Radice, MilanoArmando Santoro, Rozzano (MI)Anna Sapino, TorinoNicola Silvestris, BariFabrizio Tagliavini, MilanoAntonio Uccelli, Genova

Page 3: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

Luca AlbarelloI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Joshua ArmeniaLondon, UK

Alessandra BearzCRO - Centro di Riferimento OncologicoAviano (PN), Italy

Rosa BernardiI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Giampaolo BianchiniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Christian BlankThe Netherlands Cancer InstituteAmsterdam, The Netherlands

Chiara BoniniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Gerardo BottiIstituto Tumori Napoli Fondazione G. Pascale - Napoli, Italy

Caroline ChapusotUniversity of Burgundy Dijon, France

Fabio CiceriI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Paolo De PaoliAlliance Against CancerRoma, Italy

Angelo P. Dei TosOspedale di TrevisoTreviso, Italy

Lucia Del MastroI.R.C.C.S. Azienda Ospedaliero Universitaria San Martino - Genova, Italy

Paolo DellabonaI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Claudio DoglioniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Virginia FerraresiIFO - Istituto Nazionale Tumori Regina Elena - Roma, Italy

Gaetano FinocchiaroFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta - Milano, Italy

Rossella GalliI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Diana GiannarelliIFO - Istituto Nazionale Tumori Regina Elena - Roma, Italy

Vanesa GregorcI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Massimo GuidoboniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola (FC), Italy

Stefano IndraccoloIstituto Oncologico VenetoPadova, Italy

Luigi LaghiIstituto Clinico HumanitasRozzano (MI), Italy

Chiara LazzariI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Nicholas McGranahanUniversity College LondonLondon, UK

Invited Faculty

Page 4: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

Invited FacultyJosé Carlo MachadoIPATIMUP InstitutePorto, Portugal

Roberta MaestroCRO - Centro di Riferimento OncologicoAviano (PN), Italy

Luca MazzarellaIEO - Istituto Europeo di Oncologia Milano, Italy

Giuseppe OpocherIstituto Oncologico VenetoPadova, Italy

Roberto OrecchiaIEO - Istituto Europeo di Oncologia Milano, Italy

Pier Giuseppe PelicciIEO - Istituto Europeo di Oncologia Milano, Italy

Francesco PerroneIstituto Tumori Napoli Fondazione G. Pascale - Napoli, Italy

Piero PicciIstituto Ortopedico RizzoliBologna, Italy

Carmine PintoIRCCS Santa Maria NuovaReggio Emilia, Italy

Aleix PratHospital Clinic of BarcelonaBarcelona, Spain

Paolo PronzatoOspedale Policlinico San MartinoGenova, Italy

Sergio A. QuezadaUniversity College LondonLondon, UK

Concetta QuintarelliOspedale Pediatrico Bambino Gesù Roma, Italy

Paolo RadiceFondazione I.R.C.C.S.Istituto Nazionale dei TumoriMilano, Italy

Françoise RediniUniversité de NantesNantes, France

Francesca Maria RizzoUCL Cancer InstituteLondon, UK

Giandomenico RussoIstituto Dermopatico dell’Immacolata (IDI)Roma, Italy

Vincenzo RussoI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Anna SapinoIstituto Oncologico Candiolo Candiolo (TO), Italy

Katia ScotlandiIstituto Ortopedico RizzoliBologna, Italy

Nicola SilvestrisOspedale Oncologico “Giovanni Paolo II” IRCCS Bari - Bari, Italy

Ian TomlinsonUniversity of BirminghamBirmingham, UK

Giovanni TononI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Angela VasaturoINSERM - Cordeliers Research CenterParis, France

Michael WellerUniversitätsSpital ZurichZurich, Switzerland

Page 5: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

SCIENTIFIC PROGRAM

1.30 p.m. Opening Session - Authorities and Introduction

WORKING GROUP GENOMICS Chairs: Diana Giannarelli (Italy) - Roberta Maestro (Italy)

2.00 p.m. Joshua Armenia, United Kingdom Discovery of oncogenic drivers in cancer2.30 p.m. Luca Mazzarella, Italy

Updates from the Secretary 2.45 p.m. José Carlos Machado, Portugal

Current practice, needs and future directions in immuno-oncology research testing

Talk sponsored by

WORKING GROUP GLIOBLASTOMA Chairs: Gaetano Finocchiaro (Italy) - Paolo Pronzato (Italy)

3.05 p.m. Michael Weller, Switzerland Translating science into clinical practice in glioblastoma3.35 p.m. Stefano Indraccolo, Italy

Updates from the Secretary

3.45 p.m. Coffee Break

WORKING GROUP COLON CANCER Chairs: Claudio Doglioni (Italy) - Carmine Pinto (Italy)

4.05 p.m. Ian Tomlinson, United Kingdom Strategies for preventing colorectal cancer based on genetic

predisposition4.35 p.m. Luigi Laghi, Italy

Updates from the Secretary

4.50 p.m. SELECTED ABSTRACTS Chairs: Rossella Galli (Italy) - Paolo Radice (Italy)

5.30 p.m. PARALLEL WORKING GROUP MEETINGS

7.45 p.m. Social Dinner

MONDAY, OCTOBER 29, 2018

Page 6: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

SCIENTIFIC PROGRAM

TUESDAY, OCTOBER 30, 2018

WORKING GROUP LUNG CANCER Chairs: Alessandra Bearz (Italy) - Roberto Orecchia (Italy)

9.00 a.m. Nicholas McGranahan, United Kingdom Lung Cancer Evolution and Immune Escape9.30 a.m. Vanesa Gregorc, Italy

Updates from the Secretary9.45 a.m. Caroline Chapusot, France

Overcoming Challenges in Solid Tumor Testing with Advanced AI

Talk sponsored by

10.00 a.m. SELECTED ABSTRACTS Chairs: Fabio Ciceri (Italy) - Vincenzo Russo (Italy)

10.40 a.m. Coffee Break

WORKING GROUP IMMUNOTHERAPY Chairs: Massimo Guidoboni (Italy) - Concetta Quintarelli (Italy)

11.00 a.m. Sergio A. Quezada, United Kingdom Targeting regulatory T cells in cancer: means and mechanisms11.30 a.m. Concetta Quintarelli, Italy Updates from the Secretary11.45 a.m. Angela Vasaturo, France Unraveling the tumor microenvironment architecture

by multispectral imaging

Talk sponsored by

12.05 a.m. Chiara Bonini, Italy Adoptive Cell Therapy in Cancer

12.35 a.m. Lunch1.30 p.m.

Page 7: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

TUESDAY, OCTOBER 30, 2018

12.35 a.m. 1.00 p.m.

Lunch SymposiumAula Caravella Pinta

Anti-tumor T cell immunity at single cell resolutionEnrico Lugli, Istituto Clinico Humanitas (Rozzano - MI, Italy)

NEW TOOLS IN CANCER DIAGNOSTIC Chairs: Paolo De Paoli (Italy) - Giovanni Tonon (Italy)1.30 p.m. Francesca Maria Rizzo, United Kingdom

Analysis of Circulating Tumour Cells in Neuroendocrine Tumours

Talk sponsored by

WORKING GROUP MELANOMA Chairs: Gerardo Botti (Italy) - Virginia Ferraresi (Italy)2.00 p.m. Christian Blank, The Netherlands

Neoadjuvant immunotherapy, the pathway towards personalized immunotherapy

2.30 p.m. Giandomenico Russo, Italy Updates from the Secretary

WORKING GROUP SARCOMA Chairs: Angelo P. Dei Tos (Italy) - Piero Picci (Italy)2.45 p.m. Françoise Redini, France

The microenvironment of primary bone tumors as potential prognosis factor and therapeutic target

3.15 p.m. Katia Scotlandi, Italy Updates from the Secretary

3.30 p.m. Coffee Break

4.00 p.m. SELECTED ABSTRACTS Chairs: Luca Albarello (Italy) - Rosa Bernardi (Italy)

5.00 p.m. POSTER WALK AND DRINKS

Registration to the Lunch Symposium is requested - for more details please contact the Organising Secretariat

Page 8: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

SCIENTIFIC PROGRAM

WEDNESDAY, OCTOBER 31, 2018

WORKING GROUP BREAST CANCER Chairs: Giampaolo Bianchini (Italy) - Anna Sapino (Italy)

9.00 a.m. Aleix Prat, Spain Clinical value of the intrinsic molecular subtypes

of breast cancer9.30 a.m. Lucia Del Mastro, Italy

Updates from the Secretary

FUTURE DIRECTIONS Chairs: Francesco Perrone (Italy) - Nicola Silvestris (Italy)

9.45 a.m. Giuseppe Opocher, Italy Updates from the Secretary of WORKING GROUP

OF HEREDITARY TUMORS

10.00 a.m. SELECTED ABSTRACTS Chairs: Paolo Dellabona (Italy) - Chiara Lazzari (Italy)

11.00 a.m. Coffee Break

ROUND TABLE - FINAL DISCUSSION: the Future of Cancer Research in Italy and Europe

Chairs: Paolo De Paoli (Italy) - Gennaro Ciliberto (Italy)

11.30 a.m. Introduced by Pier Giuseppe Pelicci Towards ACC 2.0

12.00 a.m. Discussion with Armando Bartolazzi, Sottosegretario Salute (Italy), Fabien Calvo (France), Pier Giuseppe Pelicci (Italy)

12.30 a.m. Ruggero De Maria, President ACC, Italy CLOSING REMARKS

Page 9: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

Call for abstractAll those interested in taking part may submit an abstract in English, following the guidelines included in the template.

Deadlines for abstract submission and registrations Abstracts should be submitted to the e-mail address [email protected]

by September 10th, 2018.

Abstracts submitted by fax will not be accepted.

Abstracts will be reviewed by the Scientific Committee and acceptance will be confirmed, together with all details for presenting your work, by September 20th, 2018.

The presenting author of an accepted project must register by October 15th, 2018.

Registration is mandatory for presenting the poster.

Competition and prizeAccepted abstract will be reviewed by the Scientific Committee and the following prizes will be assigned:

Best oral presentation

Best poster presentation

Travel grantsWe are pleased to inform you that the Congress will assign travel grants (€ 250,00) to the registered participants.

In order to be eligible for travel grant you have to:

Have submitted an abstract to the congress (only for 1st author)

Be up to the age of 35

Page 10: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

To download the word format please click www.alleanzacontroilcancro.it/3rd-annual-meeting-of-alliance-against-cancer-milan

The form shoud be sent by e-mail to the Organising Secretariat ([email protected]) by September 10th, 2018.

PRESENTING AUTHOR (Name, Surname, Institution, Institution Address, Department, Mobile phone, e-mail)

OTHER AUTHORS

ABSTRACT TITLE

ABSTRACT TEXT (max 2500 characters - including spaces)

Background

Methods

Results

Conclusions

Please choose your Working Group: ❍ Genomics ❍ Lung cancer ❍ Breast cancer ❍ Colon cancer

❍ Melanoma ❍ Glioblastoma ❍ Sarcoma ❍ Onco-hematology

❍ Hereditary tumors ❍ Immunotherapy

Travel Grant I would like to apply for travel grant (please refer to Useful Information to check the criteria for applying)

In accordance with General Data Protection Regulation UE 2016/679 we declare that the holder of data processing is Acheloís Srl.I authorize Acheloís Srl to handle my personal data for purposes strictly connected to the present and future registrations. Achelois srl declares that this data will not be divulged or delivered to third parties, that are not strictly involved in the event management.

Signature

ABSTRACT FORM

Page 11: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

Congress VenueSan Raffaele Congress CentreCaravella Santa Maria RoomVia Olgettina 58 - Milano, Italy

RegistrationsRegistration to the Congress is free of charge for the members of the institution affiliated to Alliance Against Cancer. For all other participants the registration’s acceptance should be provided by the Organizing Secretariat and the fee is of E 150,00 VAT included. Only after official confirmation you will receive all details for the payment. You can register online through the link

http://achelois.onlinecongress.it/ACC2018

Organizing SecretariatAcheloísProfessional Congress OrganiserVia Olgettina 58 - Milan, ITPhone: +39 02 2643 6227e-mail: [email protected]

ACHELOÍS - Professional Congress Organiser

USEFUL INFORMATION

OSPEDALE SAN RAFFAELE

M

San Michele

San RaffaeleDibit 2

San Gabriele

P P

P

P

P

P

TAXI

Fermata autobus 925Bus stop 925

InformazioniInformation

TaxiTaxi

Parcheggio-Cassa

TAXI

Parking-CashP Aula San RaffaeleSan Raffaele Conference Room

HotelHotel

Inizio percorsi per tutte le destinazioniAll Destinations

Centro CongressiConvention Center

MetropolitanaSubwayM

Via Olgettina 58

Congress Centre

San Raffaele Hospital

Via F.lli Cervi

Page 12: NEW TECHNOLOGIES AND STRATEGIES TO FIGHT CANCER...Chairs: Rossella Galli (Italy) - Paolo Radice (Italy) 5.30 p.m. PARALLEL WORKING GROUP MEETINGS 7.45 p.m. Social Dinner MONDAY, OCTOBER

ACKNOWLEDGEMENTS