October 29-31, 2018San Raffaele Congress Centre, Milano

NEWTECHNOLOGIESAND STRATEGIES TO FIGHT CANCER3rd Annual Meeting

Organized in collaboration with

P R E L I M I N A R Y P R O G R A M

www.alleanzacontroilcancro.it/3rd-annual-meeting-of-alliance-against-cancer-milan

Under the auspices of

Public Affairs - Alliance Against CancerGuido Schwarz - schwarz@alleanzacontroilcancro.it

Scientific SecretariatManuela Sovilla - sovilla.manuela@hsr.it

Local Scientific CommitteeFabio Ciceri, Paolo Dellabona, Vanesa Gregorc, Vincenzo Russo, Giovanni TononI.R.C.C.S. Ospedale San Raffaele, Milano, IT

Scientific CommitteeRuggero De Maria, RomaPier Giuseppe Pelicci, MilanoGennaro Ciliberto, RomaPaolo De Paoli, Roma

Alessandra Bearz, Aviano (PN)Gerardo Botti, NapoliAngelo P. Dei Tos, TrevisoClaudio Doglioni, MilanoVirginia Ferraresi, RomaDiana Giannarelli, RomaLuca Gianni, MilanoMassimo Guidoboni, Meldola (FC)Roberta Maestro, Aviano (PN)Giuseppe Opocher, Padova

Roberto Orecchia, MilanoFrancesco Perrone, NapoliPiero Picci, BolognaConcetta Quintarelli, RomaPaolo Radice, MilanoArmando Santoro, Rozzano (MI)Anna Sapino, TorinoNicola Silvestris, BariFabrizio Tagliavini, MilanoAntonio Uccelli, Genova

Luca AlbarelloI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Joshua ArmeniaLondon, UK

Alessandra BearzCRO - Centro di Riferimento OncologicoAviano (PN), Italy

Rosa BernardiI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Giampaolo BianchiniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Christian BlankThe Netherlands Cancer InstituteAmsterdam, The Netherlands

Chiara BoniniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Gerardo BottiIstituto Tumori Napoli Fondazione G. Pascale - Napoli, Italy

Caroline ChapusotUniversity of Burgundy Dijon, France

Fabio CiceriI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Paolo De PaoliAlliance Against CancerRoma, Italy

Angelo P. Dei TosOspedale di TrevisoTreviso, Italy

Lucia Del MastroI.R.C.C.S. Azienda Ospedaliero Universitaria San Martino - Genova, Italy

Paolo DellabonaI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Claudio DoglioniI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Virginia Ferraresi IFO - Istituto Nazionale Tumori Regina Elena - Roma, Italy

Gaetano FinocchiaroFondazione I.R.C.C.S. Istituto Neurologico Carlo Besta - Milano, Italy

Rossella GalliI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Diana GiannarelliIFO - Istituto Nazionale Tumori Regina Elena - Roma, Italy

Vanesa GregorcI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Massimo GuidoboniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori Meldola (FC), Italy

Stefano IndraccoloIstituto Oncologico VenetoPadova, Italy

Luigi LaghiIstituto Clinico HumanitasRozzano (MI), Italy

Chiara LazzariI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Nicholas McGranahanUniversity College LondonLondon, UK

Invited Faculty

Invited FacultyJosé Carlo MachadoIPATIMUP InstitutePorto, PortugalRoberta MaestroCRO - Centro di Riferimento OncologicoAviano (PN), ItalyLuca MazzarellaIEO - Istituto Europeo di Oncologia Milano, ItalyGiuseppe OpocherIstituto Oncologico VenetoPadova, ItalyRoberto OrecchiaIEO - Istituto Europeo di Oncologia Milano, ItalyPier Giuseppe PelicciIEO - Istituto Europeo di Oncologia Milano, ItalyFrancesco PerroneIstituto Tumori Napoli Fondazione G. Pascale - Napoli, ItalyPiero Picci Istituto Ortopedico RizzoliBologna, Italy

Aleix PratHospital Clinic of BarcelonaBarcelona, Spain

Sergio A. QuezadaUniversity College LondonLondon, UK

Concetta Quintarelli Ospedale Pediatrico Bambino Gesù Roma, Italy

Paolo RadiceFondazione I.R.C.C.S.Istituto Nazionale dei TumoriMilano, Italy

Françoise Redini Université de NantesNantes, France

Francesca RizzoUCL Cancer InstituteLondon, UK

Giandomenico RussoIstituto Dermopatico dell’Immacolata (IDI)Roma, Italy

Vincenzo RussoI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Armando SantoroIstituto Clinico HumanitasRozzano (MI), Italy

Anna SapinoIstituto Oncologico Candiolo Candiolo (TO), Italy

Katia ScotlandiIstituto Ortopedico RizzoliBologna, Italy

Nicola SilvestrisOspedale Oncologico “Giovanni Paolo II” IRCCS Bari - Bari, Italy

Ian TomlinsonUniversity of BirminghamBirmingham, UK

Giovanni TononI.R.C.C.S. Ospedale San RaffaeleMilano, Italy

Antonio Uccelli CEBR - Università degli Studi di GenovaGenova, Italy

Angela VasaturoINSERM - Cordeliers Research CenterParis, France

Michael WellerUniversitätsSpital ZurichZurich, Switzerland

SCIENTIFIC PROGRAM

1.30 p.m. Opening Session - Authorities and Introduction

WORKING GROUP GENOMICS Chairs: Diana Giannarelli (Italy) - Roberta Maestro (Italy)

2.00 p.m. Joshua Armenia, United Kingdom Discovery of oncogenic drivers in cancer2.30 p.m. Luca Mazzarella, Italy

Updates from the Secretary

2.45 p.m. José Carlos Machado, Portugal Title TBD Talk sponsored by

WORKING GROUP GLIOBLASTOMA Chairs: Gaetano Finocchiaro (Italy) - Antonio Uccelli (Italy)

3.05 p.m. Michael Weller, Switzerland Translating science into clinical practice in glioblastoma3.35 p.m. Stefano Indraccolo, Italy

Updates from the Secretary

3.45 p.m. Coffee Break

WORKING GROUP COLON CANCER Chair: Claudio Doglioni (Italy)

4.05 p.m. Ian Tomlinson, United Kingdom Title TBD4.35 p.m. Luigi Laghi, Italy

Updates from the Secretary

4.50 p.m. SELECTED ABSTRACTS Chairs: Rossella Galli (Italy) - Paolo Radice (Italy)

5.30 p.m. PARALLEL WORKING GROUP MEETINGS

7.45 p.m. Social Dinner

MONDAY, OCTOBER 29, 2018

SCIENTIFIC PROGRAM

TUESDAY, OCTOBER 30, 2018

WORKING GROUP LUNG CANCER Chairs: Alessandra Bearz (Italy) - Roberto Orecchia (Italy)

9.00 a.m. Nicholas McGranahan, United Kingdom Title TBD9.30 a.m. Vanesa Gregorc, Italy

Updates from the Secretary9.45 a.m. Caroline Chapusot, France

Title TBD Talk sponsored by

10.00 a.m. SELECTED ABSTRACTS Chairs: Fabio Ciceri (Italy) - Vincenzo Russo (Italy)

10.40 a.m. Coffee Break

WORKING GROUP IMMUNOTHERAPY Chairs: Massimo Guidoboni (Italy) - Concetta Quintarelli (Italy)

11.00 a.m. Sergio A. Quezada, United Kingdom Targeting regulatory T cells in cancer: means and mechanisms11.30 a.m. Concetta Quintarelli, Italy Updates from the Secretary11.45 a.m. Angela Vasaturo, France Unraveling the tumor microenvironment architecture

by multispectral imaging

Talk sponsored by

12.05 a.m. Chiara Bonini, Italy Adoptive Cell Therapy in Cancer

12.35 a.m. Lunch1.30 p.m.

TUESDAY, OCTOBER 30, 2018

12.35 a.m. 1.00 p.m.

Lunch SymposiumAula Caravella Pinta

Dissecting the tumor microenvironment by high dimensional flow cytometryEnrico Lugli, Istituto Clinico Humanitas (Rozzano - MI, Italy)

NEW TOOLS IN CANCER DIAGNOSTIC Chairs: Paolo De Paoli (Italy) - Giovanni Tonon (Italy)

1.30 p.m. Francesca Rizzo, United Kingdom Title TBD Talk sponsored by

WORKING GROUP MELANOMA Chairs: Gerardo Botti (Italy) - Virginia Ferraresi (Italy)

2.00 p.m. Christian Blank, The Netherlands Neoadjuvant immunotherapy, the pathway towards

personalized immunotherapy2.30 p.m. Giandomenico Russo, Italy

Updates from the Secretary

WORKING GROUP SARCOMA Chairs: Angelo P. Dei Tos (Italy) - Piero Picci (Italy)

2.45 p.m. Françoise Redini, France The microenvironment of primary bone tumors as potential

prognosis factor and therapeutic target 3.15 p.m. Katia Scotlandi, Italy

Updates from the Secretary

3.30 p.m. Coffee Break

4.00 p.m. SELECTED ABSTRACTS Chairs: Luca Albarello (Italy) - Rosa Bernardi (Italy)

5.00 p.m. POSTER WALK AND DRINKS

Registration to the Lunch Symposium is requested - for more details please contact the Organising Secretariat

SCIENTIFIC PROGRAM

WEDNESDAY, OCTOBER 31, 2018

WORKING GROUP BREAST CANCER Chairs: Giampaolo Bianchini (Italy) - Anna Sapino (Italy)

9.00 a.m. Aleix Prat, Spain Clinical value of the intrinsic molecular subtypes

of breast cancer9.30 a.m. Lucia Del Mastro, Italy

Updates from the Secretary

FUTURE DIRECTIONS Chairs: Francesco Perrone (Italy) - Nicola Silvestris (Italy)

9.45 a.m. Giuseppe Opocher, Italy Updates from the Secretary of WORKING GROUP

OF HEREDITARY TUMORS

10.00 a.m. SELECTED ABSTRACTS Chairs: Paolo Dellabona (Italy) - Chiara Lazzari (Italy)

11.00 a.m. Coffee Break

ROUND TABLE - FINAL DISCUSSION: the Future of Cancer Research in Italy and Europe

Chairs: Ruggero De Maria (Italy) - Pier Giuseppe Pelicci (Italy)

11.30 a.m. Pier Giuseppe Pelicci, Scientific Director ACC, Italy Towards ACC 2.0

12.00 a.m. Discussion with Italian Ministry of Health Representatives, Ruggero De Maria (Italy) - Pier Giuseppe Pelicci (Italy) Gennaro Ciliberto (Italy) - Paolo De Paoli (Italy) - Fabien Calvo (France)

12.30 a.m. Ruggero De Maria, President ACC, Italy CLOSING REMARKS

Call for abstractAll those interested in taking part may submit an abstract in English, following the guidelines included in the template.

Deadlines for abstract submission and registrations Abstracts should be submitted to the e-mail address alice.trovato@achelois.eu

by September 10th, 2018.

Abstracts submitted by fax will not be accepted.

Abstracts will be reviewed by the Scientific Committee and acceptance will be confirmed, together with all details for presenting your work, by September 20th, 2018.

The presenting author of an accepted project must register by October 15th, 2018.

Registration is mandatory for presenting the poster.

Competition and prizeAccepted abstract will be reviewed by the Scientific Committee and the following prizes will be assigned:

Best oral presentation

Best poster presentation

Travel grantsWe are pleased to inform you that the Congress will assign travel grants (€ 250,00) to the registered participants.

In order to be eligible for travel grant you have to:

Have submitted an abstract to the congress (only for 1st author)

Be up to the age of 35

To download the word format please click www.alleanzacontroilcancro.it/3rd-annual-meeting-of-alliance-against-cancer-milan

The form shoud be sent by e-mail to the Organising Secretariat (alice.trovato@achelois.eu) by September 10th, 2018.

PRESENTING AUTHOR (Name, Surname, Institution, Institution Address, Department, Mobile phone, e-mail)

OTHER AUTHORS

ABSTRACT TITLE

ABSTRACT TEXT (max 2500 characters - including spaces)

Background

Methods

Results

Conclusions

Please choose your Working Group: ❍ Genomics ❍ Lung cancer ❍ Breast cancer ❍ Colon cancer

❍ Melanoma ❍ Glioblastoma ❍ Sarcoma ❍ Onco-hematology

❍ Hereditary tumors ❍ Immunotherapy

Travel Grant I would like to apply for travel grant (please refer to Useful Information to check the criteria for applying)

In accordance with General Data Protection Regulation UE 2016/679 we declare that the holder of data processing is Acheloís Srl.I authorize Acheloís Srl to handle my personal data for purposes strictly connected to the present and future registrations. Achelois srl declares that this data will not be divulged or delivered to third parties, that are not strictly involved in the event management.

Signature

ABSTRACT FORM

Congress VenueSan Raffaele Congress CentreCaravella Santa Maria RoomVia Olgettina 58 - Milano, Italy

RegistrationsRegistration to the Congress is free of charge for the members of the institution affiliated to Alliance Against Cancer. For all other participants the registration’s acceptance should be provided by the Organizing Secretariat and the fee is of E 150,00 VAT included. Only after official confirmation you will receive all details for the payment. You can register online through the link

http://achelois.onlinecongress.it/ACC2018

Organizing SecretariatAcheloísProfessional Congress OrganiserVia Olgettina 58 - Milan, ITPhone: +39 02 2643 6227e-mail: linda.isella@achelois.eu

ACHELOÍS - Professional Congress Organiser

USEFUL INFORMATION

OSPEDALE SAN RAFFAELE

M

San Michele

San RaffaeleDibit 2

San Gabriele

P P

P

P

P

P

TAXI

Fermata autobus 925Bus stop 925

InformazioniInformation

TaxiTaxi

Parcheggio-Cassa

TAXI

Parking-CashP Aula San RaffaeleSan Raffaele Conference Room

HotelHotel

Inizio percorsi per tutte le destinazioniAll Destinations

Centro CongressiConvention Center

MetropolitanaSubwayM

Via Olgettina 58

Congress Centre

San Raffaele Hospital

Via F.lli Cervi

ACKNOWLEDGEMENTS