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NEW SEATING CHARTS!!!
Make two colored model of DNA to show hoe it replicates!!! Have big model prepared and have students act as the free
floating nucleotides to come and build the new molecule..? Have the old molecule in one color and new nucleotides in
anotherMake a visual model
Manipulative ideas: have students make nucleotides Then, have each nucleotide find their matching base pair
Add pictures to the pptMake check Points throughout!!!!!!!ADD more short videos
Osmosis Jones Questions Continued…
What is the plan that Thrax has for Frank’s body? Why does he think the plan will work?
What part of Frank’s body controls the temperature? Where is it located?
What did Ozzie’s ancestors come over on?
What does Thrax intend to do to Shane, Frank’s daughter? What does Frank do that passes Thrax onto Shane?
How is Thrax killed?
DNA Vocabulary Acquisition Reverse Crossword
Make a crossword using the words from the vocabulary.
1. Write the words on the graph paper provided in a crossword fashion.
2. Number each of the words in the order you wrote them and frame the letters in individual boxes. 3. On a separate sheet, write the corresponding
clues for words written across and down and assign each a number.
You can use your vocabulary, notes, and or textbook to find complete the assignment. Due end of period
Example:
1T R A 2N
S C R I B E
R U
A 3C
H R O M O T I N
N
L
S E
F O
E T
R I
R D
N
E
A
Across Down1. To rewrite; RNA does this with 1. Carries amino acids to
the ribosome DNA 2.
monomer of nucleic acid; made of a sugar, 3. Genetic material in the nucleus, a phosphate and a nitrogen base
becomes chromosomes during mitosis
Warm Up Do Now
What do we already know about DNA…
1. Where is DNA found in eukaryotic plant and animal cells? Prokaryotic cells?
2. What is the shape of DNA in eukaryotic cells? In prokaryotic cells?
3. DNA is what type of organic molecule?4. DNA is made from what subunit or building
block? 5. What is the function of DNA?
Why is DNA important?
DNA is like the blueprint for your body!
It is an extremely long strand of directions for all of the proteins that allow living things to function
Think of DNA as the recipe for making proteins
How SIMILAR are you to the person sitting next to you?
You are 99% identical to the person sitting next to you!!
The only difference it the ORDER of your NITROGEN BASES!
What is COMPLIMENTARY BASE PAIRING?
The same bases will ALWAYS pair together!
A pairs with TC pairs with G
ALWAYS!!! (Unless there is a mutation)
How is a DNA molecule MADE?
Nucleotides come together
Then, HYDROGEN bonds form between the nitrogen bases
This makes TWO strands of nucleotides which twist into a DOUBLE HELIX
What are HYDROGEN BONDS?
The bonds that form between the nitrogen bases
They are very WEAK and break easily This is how DNA is able to make new copies of itself!
DNA Math
If there are 10 A’s, then there must be 10 T’sIf there are 40 G’s then there must be 40 C’s
So, if there are 30 A’s How many T? How many G? How many C?
DNA Math Example
There are 500 total bases in a specific DNA molecule. Of the 500 bases, 100 are A’s.
How many are T’s?
How many are C’s?
How many are G’s?
DNA Stations
1. Practice Questions2. DNA Math3. Nucleotide Build
1. T = Blue2. A = Purple3. C = Green4. G = Red
Building Our Own DNA Molecule
You will be working in groups of 3 to build a nucleotide
Once your nucleotide is built, your will use the complementary base pairing rules to build a DNA molecule with the class
DNA Molecule Synthesis
Using your experience with the DNA build activity, quietly work with your partner to complete the activity synthesis practice
DNA Replication
http://www.youtube.com/watch?v=zdDkiRw1PdU&feature=related
What is DNA REPLICATION?
NEW cells are made by copying OLD cells
Before a cell divides, you have to copy or REPLICATE the DNA
REVIEW!What stage of the cell cycle doesDNA Replication happen in?
When does DNA Replication occur?
During S –Phase of INTERPHASE
S-Phase = Synthesis Phase
The DNA Replicates (copies itself ) to prepare for cell division (MITOSIS!!!)
What are the STEPS for DNA Replication?
1. An Enzyme “UNZIPS” the 2 strands of DNA by breaking the weak Hydrogen bonds
2. New nucleotides are added to the old stand REVIEW: A = T and C = G
3. Another Enzyme “ZIPS” the strands back up4. DNA Polymerase (an enzyme) “proofreads” the
strands to make sure there are no MISTAKES!
What do you think might happen if
there are mistakes?!
What is the ROLE of ENZYMES?
Enzymes help to:1. Split the DNA in half2. Put DNA back together3. Proofread for any mistakes in
the base pairs
How is DNA Replication SEMI-CONSERVATIVE?
When the DNA copies itself, it always has HALF of the parental (OLD) strand and HALF of the daughter (NEW) strand
In other words: the DNA is HALF OLD and HALF NEW
What are MUTATIONS?
Changes in the genetic code (DNA)Can be: positive, negative or neutralCauses: UV radiation, chemicals, bad DNA
proofreading Can lead to CANCER
How to Find a Mutation…
Original DNA Sequence:
T A C A C C T T G G C G A C G A C T
Complementary Strand:
A T C G G G A C C C G C T T G T G A
Corrected Strand: