NEUSOFT NSM-P035

Super Open

Magnetic Resonance Imaging System

Outline

MRI Introduction –principles 、 features 、 clinical

applications、 development trend

Features of NEUSOFT MRI NSM-P035 –hardware ：magnet、 RF、 gradient、 computer

–software： imaging technology、 technical

specifications、 sequence、 operating interface

Principles of MRI

Nuclear magnetic resonance phenomenon

Hydrogen nucleus —proton

Spin and Magnetic Moment

Pri

nci

ple

s o

f M

RI

Magnetization

Proton Precession

Pri

nci

ple

s o

f M

RI

Resonance Relaxation

Pri

nci

ple

s o

f M

RI

MR Signal

Pri

nci

ple

s o

f M

RI

Features of MRI

Non-invasive

examination

Multi-type of images

High image contrast

Slicing at any orientation

No contrast agent

required in MRA

Fea

ture

s o

f M

RI

Non-invasive examination

CT 、 X-ray 、 Nuclear medicine– ionizing radiation

Radiation energy of MRI is 1/1012 that of X-ray system

No definite trauma has been certified since more than 20

years clinical application

Pregnant woman can be inspected by MRI, not CT

MRI interventional therapeutic procedure ， no trauma to

doctor and patient

Fea

ture

s o

f M

RI

Multi-type of images

T2 weighted

Water suppression

IR T2 weighted

T1 weighted

IR T1 weighted

To get more diagnosis information by comparing various

images

To improve detectable rate and accuracy of clinical diagnosis

Fea

ture

s o

f M

RI

High Image Contrast

Water

Fat

Protein

Skeleton

Gas

Fea

ture

s o

f M

RI

Slicing at any orientation

Fea

ture

s o

f M

RI

No Contract Agent Need in MRA

In-flow and out-flow

effect

TOF

PC

MRI Clinical Applications

MRI Diagnose Advantage Parts

Nervous system

Spine 、 extremity

Muscle 、 convective tissue

Angiography system

Pelvis

Substantive organs

MR

I Clin

ical

Ap

plic

atio

ns Head

Brain Stem Infarct

Coronal T2

Coronal FLAIR

MR

I Clin

ical

Ap

plic

atio

ns

Pituitary Tumor

Arrow T1

Coronal T1

MR

I Clin

ical

Ap

plic

atio

ns

Spine and Spinal Cord

Spinal Cord Malacosis

Sagittal T1 Sagittal T2

MR

I Clin

ical

Ap

plic

atio

ns

Lung Cancer Lumber Transfer

Axial T1

Sagittal T2

MR

I Clin

ical

Ap

plic

atio

ns

Extremity 、 Joint

MR

I Clin

ical

Ap

plic

atio

ns

MR

I Clin

ical

Ap

plic

atio

ns

Angioma of Liver

Abdomen

Pelvis

MR

I Clin

ical

Ap

plic

atio

ns

MR

I Clin

ical

Ap

plic

atio

ns Breast

MR

I Clin

ical

Ap

plic

atio

ns Strongpoint of MRI Imaging

No trauma——meet for patient requirement for health care

More detectable rate——decrease misdiagnosis

More accurate diagnosis

-- reduce wrong diagnosis

More quantitive information

–Increase estimation prognosis accuracy

–Assist making better therapy plan

More impersonality evidence——decrease law risk

MRI Development Trend

High field

more than 1.5T 30％

Permanent magnet open 70％

Medium field quits basically from market

MRI Market Status

MR

I Dev

elo

pm

ent

Tre

nd Comparison of the Kinds of Magnet

Item\Kind Permanent magnet

Conventional resistive magnet

superconducting magnet

Field strength low low high

Image quality low low high

function less less more

Maintenance cost

less medium more

price low medium high

Trouble rate low medium high

MR

I Dev

elo

pm

ent

Tre

nd

Clinical Application Comparison of Permanent and Superconducting Magnet

95％

Conventional clinical application

Majority advanced function

Low field permanent

5％

Claustrophobic patient

Fat patient

Less embedded metal

Joint motion analysis

MRI intervention

High field superconducting

5％

Imperceptible pathological

changes

Functional imaging

Spectrum analysis

MR

I Dev

elo

pm

ent

Tre

nd

Evolvement History of Permanent Open MRI

MR

I Dev

elo

pm

ent

Tre

nd

NEUSOFT MRI Technology Development

Sparkler 1.5T

Superconducting

1.5T

NAM-P023A

C-type Super Open 0.23T

NSM-P035

C-type Super Open 0.35T

NSM-P035 Permanent Magnet MRI

Most successful magnetic field strength in permanent magnet systems

NSM-P035 facts

SNR is 2.66 times more that 0.2T ， improve

greatly image quality

Double scan speed of 0.2T, increase scan speed

Increase spatial resolution, 0.2mm slice

thickness

Provide firm foundation for future upgradeNS

M-P

035

Per

man

ent

Mag

net

MR

I

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Relation between Image SNR and magnet

strength

0.2T 0.3T 0.35T Super 0.5T

SNR

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Noise Effect upon Image Quality

NS

M-P

035

Per

man

ent

Mag

net

MR

I Advanced Magnet Technology

Type： permanent magnet

Advanced permanent magnet material －－ NdFe

Whole integrated foundry

Self-shield technology

Eddy current free technology

Self-constant temperature technology

–Insure long stable operation

The most advanced open magnet—C-type 2-column super open

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Super open—4 sides open

Decrease patient claustrophobic feelin

g , expand patient volume

Positioning of any part of patient at th

e center of magnet ensures the high i

mage quality

Convenient for interventional treraphy

NS

M-P

035

Per

man

ent

Mag

net

MR

I

The most convenient design of patient couch

Couch is separate from magnet

2 D movement with maximum

distance 160cm

Accurate laser localization

system

Easy system positioning

Space saving

Minimal Installation Area Less Environment Requirement

NS

M-P

035

Per

man

ent

Mag

net

MR

I

30m2 installation area only

Lowest height 3m

Temperature control only need

popular air conditioner

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Powerful Gradient System Gradient Amplifier

–Maximum gradient strength： 16mT/m， e

nsure high spacial resolution

–Rising time： 300μs( up to 98%）

–Slew rate： 52mT/m/ms， increase the sc

anning speed

–air cooling， no additional expenditure

Gradient coils

–plane fingerprint design

–assure accurate spacial positioning

High Efficient RF System

RF Amplifier

– RF power reach to 5KW, which leads to the high

signal frequency

RF transmitter coil

– Quanture(QD) design

– Signal-to-Noise ratio is 40% higher than normal c

oil

longitudinal resonance signal efficiency is higher tha

n transversal resonance signal efficiency by 40%

NS

M-P

035

Per

man

ent

Mag

net

MR

I

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Comprehensive Receiving coils

7 standard configuration ：QD head coil QD Neck Coil QD Body Coil

QD Extremity Coil Flat Spine Coil Breast Coil

NS

M-P

035

Per

man

ent

Mag

net

MR

I Computer System

High configuration and performance

–CPU: Pentium IV 2.4GHz

–RAM ： 1.5GB

–HD ： 120GB －－ capability of storing 0.9 million images

–peripheral storage ： 2.3GB MO or 640MBCD-R

–monitor ： 21” SONY high rosolution color display

monitor resolution ： 1600×1200

Windows operating system, easy to learn and use

Abundant in backup source, minimum cost in maintenance and up

grade

Optional Accessories

Mutual intercom system

Hi-Fi stereo sound

Laser Imager

NS

M-P

035

Per

man

ent

Mag

net

MR

I

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Advanced Imaging Techniques

Multi-slice/Multi-angle

Gating Technology

Partial echo

Flow compensation

Anti-wrap-around artifact elimination

Multi-region pre-saturation

Optimized bandwidth

Optimized data acquisition

NS

M-P

035

Per

man

ent

Mag

net

MR

I Performance Specifications

• TE(min): 2ms

• TR(min): 6ms

• FOV: 26-400mm

• Slice thickness(min) 2D: 2mm

• Slice thickness(min) 3D: 0.2mm

• Number of slices ： 64(2D)

128(3D)

Thickness

2mm

FOV 50mm

Abundant Imaging Sequences

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Spin Echo (SE)

Gradient Echo （ GE ）

IR, FLAIR, STIR

MSME

MRA

FSE

MRU 、 MRCP ）

3D GE ， 3D SE

DWI

Spin Echo（ SE)

neck sag. knee joint sag.

NS

M-P

035

Per

man

ent

Mag

net

MR

I

The most common sequence in clinical routine

Clear image

Display anatomic image

Only apply to T1 weighted imaging at present

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Fast Spin Echo (FSE）

fast image acquisition commonly used for T2 weighted imaging

Liver T2/W Head

T2/W

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Gradient Echo (GE）

T1/W T2/W

Fast image acquisition

Sensitive to bleeding

IR , FLAIR

T2/W Water suppression N

SM

-P03

5 P

erm

anen

t M

agne

t M

RI

Suppress free water

Infarct displayed clear

Judge focal composition

IR, STIR

T1/W Fat suppression

Fat suppression signal

Judge focus composition

Other parts displayed much clearer

NS

M-P

035

Per

man

ent

Mag

net

MR

I

MRA

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Carotid MRA

Need not media contract

TOF

MOSTE

MTC

MIP projection

Vein and artery displayed separately

MRCP ， MRU

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Bile duct Obstruction

MRCP and MRU

–Magnetic Resonance Cholangiop

ancreatography (MRCP)

–Magnetic Resonance Urograpgy

(MRU)

–Magnetic Resonance Myelograp

hy (MRM)

Mainly diagnose obstruction expandi

ng

NS

M-P

035

Per

man

ent

Mag

net

MR

I 3DFE

Super spatial resolution scanning

Reconstruction at any orientation

Narrow-space reconstruction

Improve greatly diagnosis capacity of small organ and small focus

  Diffusion Weighted Imaging(DWI)

Discover early brain infarct

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Powerful User-friendly Software

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Own copy-right

User-friendly design

User-friendly interface, easy to operate

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Pre- registration

Various parameters available to

be modified

Self-defined sequence

User -defined sequence library

User-friendly Browse Functions

NS

M-P

035

Per

man

ent

Mag

net

MR

I

real-time multiple image display

Multi-sequence parataxis images

contrast

Multi-case review simultaneously

Image rotation, flip

Image zoom in/out/panning

Continues window width and level

adjustment

NS

M-P

035

Per

man

ent

Mag

net

MR

I Advanced Search Function

As many as six search items with combination

search condition

Sorted by anyone of six items

The image can be obtained with associated search

result.

Comprehensive Image Processing

NS

M-P

035

Per

man

ent

Mag

net

MR

I

ROI measure (maximum, minimum, standard

deviation, interval)

ROI cut/paste

Image mark Annotation

Dynamic analysis (average, curve)

Filtration function dramatically enhance the

image quality

3 D image processing

NS

M-P

035

Per

man

ent

Mag

net

MR

I

MIP (Max intensity projection)

MRP (Multi Reconstruction of Plane)

Cine Display

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Observe blood vessel flow

Exam focus solid form

3D rotary 3D image

High Efficient Photo Interface

NS

M-P

035

Per

man

ent

Mag

net

MR

I

DICOM compatible transmission

Support a variety of image format

Filming preview

System Maintenance

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Operator grant user right

Database archive

Default/resetting system parameters

Operation training

Maintenance training

Installation training on site

After-sales service training

Effective Training Program

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Software free upgrade

NS

M-P

035

Per

man

ent

Mag

net

MR

I

Sequence is the core technology in the developme

nt of MRI system

Superconducting sequence technology is transpla

nting to permanent magnet

Only free software upgrade can

– ensure the system keep advanced t

echnology

– prolong system effective lifetime

Powerful capability on research and development

Fulfilled our commitment

–Users with version 1.0 have been upgraded to

2.0

–The version 2.2 is going to released soon.

Highest field strength with the best

image in permanent MRI system

Abundant image sequences, user-

friendly operating interface

High performance-cost ratio , and low

maintenance cost

Free software upgrading thinks with

your future

NSM-P035 Summary

NS

M-P

035

Per

man

ent

Mag

net

MR

I