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Neuroimage Analysis CenterAn NCRR National Resource Center
http://nac.spl.harvard.edu
Viewing essentials
‡GE Research §Isomics¥Surgical Planning Laboratory, Brigham and Women’s Hospital
James Miller, Ph.D.‡. James Ross, M.Sc.‡, Xi Wang, Ph.D.‡, Steve Pieper, Ph.D.§, Wendy Plesniak, Ph.D.¥
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Requisites, expectations and adaptations
Clinicians and researchers need and expect imaging platforms to provide stock capabilities
Window/level Pan/zoom Annotation Probe Measurement Oblique reformat Volume rendering Lightbox
How do we adapt these concepts to a Slicer experience?
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Lightbox
http://www.brighamandwomens.org/excellence/neuroscience.aspx
?
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Standard lightbox viewing
http://www.brighamandwomens.org/excellence/neuroscience.aspx
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with overlays
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with annotations
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with fiducials
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with multiple reformations
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with an editor
X
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Oblique reformat
• Anatomy is rarely predominantly aligned axially, sagitally, or coronally
• Oblique reformation allows image display planes to be aligned to an anatomy’s principal axes
Axial
Oblique
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Standard oblique reformat
CTRL-Right Button to manipulate reformation
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with lightbox
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Comparing series and studies
• Longitudinal analysis• Cross-sectional analysis
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Standard comparison of studies
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with overlays
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with annotations
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with fiducials
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… after registration
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with lightbox
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
… with oblique reformation
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Applications
Atlas construction Manual delineation Quality control Cross-sectional comparison of atlas subjects before and after
aligning to common coordinate frame Cross-sectional comparison of atlas subjects to constructed
atlas Atlas application
Comparison of atlas to new subject Cross-sectional comparison of new subjects aligned with
atlas Longitudinal analysis
Response to therapy
Neuroimage Analysis Center http://nac.spl.harvard.eduAn NCRR National Resource Center
Image viewing is still predominantly 2D
Native format of acquisition Precision dimensional measurements Multiplanar reformat (axial, sagittal, coronal) provides a natural
(perhaps comfortable) navigation paradigm Lightbox provides a mechanism to display 3D relationships Oblique reformats provide a mechanism to mitigate 3D effects
(improve accuracy of dimensional measurements) Longitudinal and cross-sectional comparisons build on the same
framework of linked controls and coordinate frames Slicer3 allows all these capabilities to be layered due
incorporation of coordinate frames at a fundamental level of the viewing pipeline
