Neoplasms of the Vascular System

Hemangioma Increased number of vessels-

hamartoma Capillary-small channels Cavernous-large channels Pyogenic granuloma-proliferating

vessels in inflammation Pregnancy tumor

hemangioma

hemangioma

Giant hemangioma- may sequester platelets

Lymphangioma Simple-capillary type Cavernous-Cystic Hygroma

Glomus Tumor Benign, painful tumor of glomus body A thermoregulator A-V anastomsis

Vascular Ectasia Nervus flammeus-Sturge-Weber

syndrome Spider Telangiectasia (Osler-Weber-

Rendu Disease)

Port wine stain- nevus flammeusSturge-Weber syndrome

Bacillary Angiomatosis

Opportunistic infection of immunocompromised individuals(AIDS)

Bartonella henselae (cat scratch) Nodules of proliferating capillaries -with

nuclear atypia and mitoses & neutrophils Cat is the reservoir and the cat flea is the

vector B. quintana causes trench fever-louse is

vector

Kaposi’s Sarcoma Classic-old men, lesion on lower

extremity Lymphadenopathic-(African) young Transplanted associated-skin and

internal lesions AIDS associated Viral associated-herpes type 8

Kaposi Sarcoma (AIDS associated)

Kaposi sarcoma

Hemangioendothelioma Intermediate between benign and

malignant

Angiosarcoma

Malignant neoplasm of vessels Older adults-skin, soft tissue, breast, and

liver Angiosarcoma of liver-rare but important

because Thorotrast-a radioactive contrast medium Polyvinyl chloride exposure among workers

Of arm - Induced by radiation & surgery for Breast cancer

Angiosarcoma of liver

Enviromental factors:-thorotrast a contrast agent-Polyvinyl chloride

Hemangiopericytoma Rare Most on lower extremity

Neoplasms of the HeartPrimary

Rare Myxoma - benign, most common in atrium, mimic

mitral stenosis Rhabdomyoma- in infants & children Sarcoma

Secondary Malignant melanoma Lung carcinoma Breast carcinoma Lymphoma-Leukemia

Atrial myxoma-acts like mitralstenosis

Atrial myxoma