Neauvia New Catalogue

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    The new 2 nd generation of HA

    fillers

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    Neauvia Organic is the world’s first line of fillersso close to nature.

    It has been developed using the latesttechnologies, ensuring an unprecedented purity

    and efficiency of preparations.

    Pure raw materials and new productiontechniques make Neauvia fillers stand out as the

    new generation of products.

    TECHNOLOGY OF

    THE 21ST

    CENTURYSERVING MEDICINE

    CATALOGUE | INTRO

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    HYALURONIC ACID FROMBACILLUS SUBTILIS

    Hyaluronic acid (HA) llers owe their popularity to good results, lowintrusiveness and safe application. However, there are rare cases where apatient’s body reacts to them against expectations.

    Why does this happen?

    Currently, the most popular source of HA are laboratory strains ofStreptococcus.

    In fact, extracting the precious acid out of them requires the bacteriamembrane breaking and application of chemical solvents. Contaminantspresent in the nished product are precisely the residues of bacteria andsolvents. Despite several purifying processes, today’s technology is unable tofully eliminate these impurities.

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    The purest form of hyaluronic acid currentlyavailable is obtained from Bacillus subtilis.This bacterium, which is non-pathogenic tohumans, produces HA in a process based on water usage.

    Unquestionable advantages of Bacillus Subtilis Hyaluronic Acid:

    • Ultra purity

    • High safety of application

    • Pre-determined molecular mass

    • Possibility to apply high HAconcentration

    • Long shelf life

    HYALURONIC ACID

    HAS NEVER BEEN SO PURE!

    THIRD PHASE

    • PRESENCE OF RESIDUAL ENDOTOXINAND CHEMICAL SOLVENTS

    • UNPREDICTABLEMOLECULAR WEIGHT RANGE

    STREPTOCOCCUS

    CELL SPLITTING

    CRASHING REACTION/EXTRACTION

    • NO ANIMAL DERIVED MATERIALS

    • NO ENDOTOXIN

    • NO SOLVENTS,WATER BASED PROCESS ONLY

    BACILLUS

    UNMATCHED PURITY, TARGETED MW ANDHIGH BATCH/TO/BATCH CONSISTENCY

    BACILLUS-BASED PROCESS

    RELEASE

    CATALOGUE | INTRO

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    Safety and effectiveness of llers also depend onhow they are stabilized. Usually BDDE (a crosslinkingagent) is used for this purpose.

    Due to its toxicity, it is assumed that the lowerits content is, the safer is the product. However,low amount of cross-linker reduces longevity andperformance in the tissue.

    CROSSLINKING WITHPEG POLYMER

    While others wonder how to reduce the contentof undesired substances, the scientists workingon Neauvia Organic llers decided to apply a newcrosslinker PEG polymer (not a common monomerlike DVS or BDDE used in all the other products onthe market). PEG is a well-known polymer on the

    pharmaceutical market, but it has been used for therst time in ller production by Neauvia .

    No more choosing between

    safety and permanent effect

    PEG outstanding advantages:

    • Not-toxic and completely degradable in the tissues

    • Reduces the action of proteolytic enzymes, likehyaluronidase, increasing the longevity of the implant

    • Stops the immunological reaction, as the implantsis not recognized as a foreign body

    PEG makes Neauvia Organic the most biocompatiblellers on the market reducing almost to zero the

    biopotential rejection of the hosting tissues.

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    IMMUNOLOGICAL SHIELDFOR SAFETY AND LONGEVITY

    Protective action of PEG is able to mask theimplant from the host organism reducing the risk ofimmunological reaction and formation of the foreignbody giant cells (FBGC). In other words, PEG reducesin ammation and granulomas formation.

    Moreover, it delays the degradation and thebioabsorbtion of the implant.

    PEG makes Neauvia llers the rst, one and onlyBIOMIMETIC llers worldwide.

    first phase second phase

    CATALOGUE | INTRO

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    IPN stands for Interpenetrating Polymer Network,

    which is an innovative and advanced technology tocombine two different polymers - here HA and PEG - in one network that gives outstanding mechanical,rheological and thermosensitive properties to Neauvia

    llers. The use of this technology in Neauvia Organic llers is possible thanks to PEG , which, unlike other

    current cross-linker agents, is a polymer.

    These kinds of IPN structures can be degraded only with the break of the chemical bonds, which meansthat the ller is much more resistant to mechanicalstress that is the rst natural cause of the degradationof the implant.

    The aim of IPN is to improve the weak properties of

    the single polymers; the combination of 2 polymers with IPN technique is improving both polymersperformances. For instance, hyaluronic acid is atremendously important component of our tissues, butreally sensitive to heat! At certain temperatures, likethe ones reached with aesthetic medicine treatmentslike lasers, ultrasounds or RF, any HA ller on themarket is spoiled, besides Neauvia ones! PEG makesthe HA much more resistant to heat, not limiting therange of aesthetic procedure available in beauty clinicsand hospitals.

    HYALURONIC ACID

    REAL IPNTECHNOLOGY

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    THE best

    RHEOLOGICAL RATIO ON THE MARKET

    The different and optimum rheology of each single Neauvia ller allows the substance to adapt itself tothe receiving anatomic structures while, at the sametime, keeping the desired shape for a long lastingaesthetical correction. Neauvia llers are able to createthe desired volume without inducing compression tothe surrounding tissues, so always providing naturalresults.

    Thanks to PEG features and to a precise technique of determining the molecular weight of the HA, Neauvia llershave the most optimal rheology - the ratio of three properties – on the market:

    Furthermore, there is absolutely no migration of theimplant in the tissue, something unfortunately quitecommon with many other similar products on themarket! This is always due to the use of PEG polymer which is really creating a totally different new conceptof HA ller worldwide!

    • Cohesivity : the attractive force acting between themolecules of a substance.

    • Viscoelasticity : the ratio between Viscosity (the propertyof resistance to ow in a uid/semi uid; adjacent layersmove parallel to each other with different speeds) and Elasticity (the tendency of solid materials to return totheir original shape after being deformed).

    • Plasticity : the property to undergo permanentdeformation under load.

    CATALOGUE | INTRO

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    The aging process gradually deprives skin not only of

    hyaluronic acid, but also of collagen; these precioussubstances, naturally produced by broblasts, areresponsible for the skin’s density and exibility.Reduction of the amount of these substances cause theappearance of wrinkles and aged skin.

    A solution that really prevents the aging process is a Neauvia ller with the unique combination of hyaluronicacid and calcium hydroxyapatite (CaHA), which is anaturally occurring mineral, safe for the human bodythat stimulates the process of neocollagenesis whenplaced in the skin. After application, the density and theelasticity of the skin are both improved, while obtaining

    the perfect volumetric effect from the HA and the bestrevitalizing effect from the CaHA.

    Thanks to the small size and low concentration

    of CaHA molecules, Neauvia Stimulate fillers areextremely safe: CaHA particles are trapped in thepolymer’s clusters during the manufacturing processthus preventing their migration.

    During the natural degradation of the product, thereis the release of small particles of CaHA (between8 and 12 microns only), few at times, that have theright size to stimulate fibroblasts in producing notonly collagen, but also elastin, glycosaminoglycansand hyaluronic acid.

    The R&D team at Neauvia Organic gave birth to a

    unique filler worldwide, the first ever with a doubleaction - Stimulate - (see page 20) which provides volumization and collagen production at the sametime! It is easy to understand that doctors andpatients will experience longer lasting aestheticalcorrection due to the combined action of HA andCaHA.

    Medical reports have shown that these particular Neauvia fillers, combining HA with CaHA, havemore collagen production than any other HA fillerand comparable to dedicated collagen stimulationproducts.

    CALCIUM

    HYDROXYAPATITE SUPPLEMENT

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    The use of CaHA is not a new concepton the market, but Neauvia Organic Stimulate is different from the otherproducts on the market because of:

    1. The small sizes of CaHA particles whichdo not interfere with phagocytes activities

    2. The CaHA molecules which are graduallyreleased during the degradation of theimplant, not all at once

    3. The safe and optimal concentration of CaHA,

    which is able to provide excellent results withoutcreating side effects. Higher concentrations ofCaHA, without any controlled release during thetime, may lead to the formation of macromoleculesof CaHA that starts the immunological reactionand the formation of capsules and granulomas.

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    products

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    intense: P . 16

    intense lV: P . 17intense lips: P . 18

    intense rose: P . 19

    RHEOLOGY: P . 21

    stimulate: P . 20

    bio active fillers(CROSSLINKED)

    HYDRO DELUXE: P . 22

    bio active REVITALIZERS(not CROSSLINKED)

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    CATALOGUE | PRODUCTS

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    intenseBIO ACTIVE FILLER

    This product contains a highest available concentrationof hyaluronic acid - 28 mg/ml. Like all Neauvia llers, it ismade from the purest source of hyaluronic acid (Bacillussubtilis) and it is cross-linked with PEG polymer to obtain a3D hydrogel matrix. Intense gives fantastic volumetric resultsshaping the injected area in a natural way. Thanks to uniquerheological properties, Intense is highly adaptive to the tissue, which helps to achieve desired results. It is suitable especiallyto deep lling of skin depression (included deep wrinkles andnasolabial folds), cheeks, chin and nose modeling and facecontouring, in moderate and strongly aged skin.

    Benefits

    • High concentration of HA and high viscosity

    • Ultra-safe pro le thanks to Bacillus subtilis and PEG

    • Optimal rheology properties giving remarkable andnatural correction

    • Slow biodegradation and long lasting results

    Concentration28 mg/ml HA, cross-linked with PEG

    Syringe1 x 1 ml

    IndicationDeep tissue restoration of volume &correction

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    intense lVBIO ACTIVE FILLER

    This product contains an high concentration of hyaluronicacid - 26 mg/ml. Like all Neauvia llers it is made from thepurest source of hyaluronic acid (Bacillus subtilis) and it iscross-linked with PEG polymer to obtain an ipn technology.It gives fantastic volumetric results shaping the injectedarea in the natural way. Thanks to the advantages of IPNtechnology Intense LV is highly adaptive to the tissue whichhelps to achieve desired results. It is suitable especiallyto deep lling of skin depression (included deep wrinklesand nasolabial folds), cheeks, chin and nose modeling, facecontouring, in moderate and strongly aged skin.

    Concentration26 mg/ml HA, cross-linked with PEG

    Syringe1 x 1 ml

    IndicationDeep tissue restoration of volume &correction

    Benefits

    • High concentration of HA and high viscosity

    • Ultra-safe pro le thanks to Bacillus subtilis and PEG

    • Optimal rheology properties giving remarkable andnatural correction

    • Slow biodegradation and long lasting results

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    CATALOGUE | PRODUCTS | FILLERS

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    New product designed particularly for mucosa tissue.It contains 24 mg/ml of HA to provide optimal results indelicate lips area. Suitable for augmentation, contouringand revitalization of lips. Intense Lips users can be sureof its highest quality thanks to the usage of the safestmaterials in the production process (BSHA, PEG ), as wellas the advanced IPN technology offering extraordinaryproperties of the hydrogel. This dedicate preparation givesspecial elasticity to the plymer’s chains and permit it toovercome the mechanical stress the lips are submitted . Thisimprovement give a natural touch perception.

    Benefits

    • Optimal amount of HA for natural effect and patient’scomfort

    • Highest quality raw materials (BSHA and PEG )

    • Real 3D structure thanks to IPN technology

    • Slow biodegradation and long lasting results

    Concentration24 mg/ml HA, cross-linked with PEG

    Syringe1 x 1 ml

    IndicationLips augmentation and modelling

    intense lipsBIO ACTIVE FILLER

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    intense roseBIO ACTIVE FILLER

    Out of concern for the intimate health and beauty, Intense Rose is dedicated to correcting lipoatrophy and tissueaugmentation in private parts. It is characterized by thehighest amount of hyaluronic acid - 28 mg/ml - and high viscosity of the hydrogel to guarantee 100% satisfactionfor the patient. Intense Rose is a combination of ef ciency,safety and longevity. Like all Neauvia llers it is made usingthe purest hyaluronic acid available and cross-linked withPEG polymer to obtain an IPN technology.

    Benefits

    • High concentration of HA and high viscosity level forgreat volume effects

    • The highest quality raw materials and safe usesupported with clinical trials

    • Unique products for speci c indications

    • Slow biodegradation and long lasting results

    Concentration28 mg/ml HA, cross-linked with PEG

    Syringe1 x 1 ml

    IndicationGynecological soft tissue correction, tissueaugmentation, lipodistrofy correction

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    CATALOGUE | PRODUCTS | FILLERS

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    Neauvia Organic Stimulate is a unique product, the only one which offers not only great lling effect but also a long term bio-stimulation. The 26 mg/ml of HA is complemented with 1% ofcalcium hydroxyapatite - a mineral occurring naturally in humanbody able to stimulate collagen production. Stimulate is a perfectchoice every time when a patient is suffering from the lack of volume and density. The product immediately will ll the tissuede cits giving the desired shape and volume gradually improvingthe quality of the skin. The neocollagenesis process permits alonger lasting correction. Stimulate is made from hyaluronicacid derived from Bacillus subtilis and it is cross-linked by PEG

    polymer using a real IPN technology. Calcium hydroxyapatiteused in Neauvia llers has small particle size (8-12 microns) and is well spreaded in the cluster of the hydrogel. This assure stabilityof the particles that have no possibility to migrate.

    Benefits

    • Unique combination of lling and biostimulation• Signi cant improvement in skin density level

    • Clinically proved results

    • Ultra-safe pro le thanks to Bacillus subtilis and PEG

    • Slow biodegradation and long lasting results

    Concentration26 mg/ml HA, cross-linked with PEG

    Syringe1 x 1 ml

    Contains1% CaHA

    IndicationDeep lling of skin depression (includeddeep wrinkles and nasolabial folds),

    biostimulation and revitalisation

    stimulateBIO ACTIVE FILLER

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    CATALOGUE | PRODUCTS | FILLERS

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    RHEOLOGYBIO ACTIVE FILLER

    The new products in Neauvia Organic line, Rheology isdedicated for correcting first signs of aging: fine linesand superficial wrinkles especially in young skin. It isalso suitable for lip’s barre code correction, light lipscorrection and hands rejuvenation. It contains 22 mg/mlof hyaluronic acid derived from Bacillus subtilis and it iscross-linked with PEG polymer. In addition to hyaluronicacid it contains amino acids - Glycine and L-Proline - thatare main ingredients of collagen.

    Benefits

    • Natural correction of super cial and moderate wrinkles

    • Collagen stimulation

    • Visibly results in quality of the skin

    • Ultra-safe pro le thanks to Bacillus subtilis and PEG

    Concentration22 mg/ml of HA, cross-linked with PEG

    Syringe

    1 x 1 ml

    ContainsGlycine and L-Proline

    IndicationFine line reduction, light corrections,orbital area, glabella

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    CATALOGUE | PRODUCTS | FILLERS

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    HYDRO DELUXEBIO ACTIVE REVITALIZER

    Mesotherapy is one of the most popular aesthetictreatments that signi cantly improve quality of the skin.The aim of it is to deliver active substances directly to theskin and to give an immediate hydration.

    Benefits

    • High concentration of HA for great hydration

    • Improvement in skin density level thanks tohydroxyapatite

    • Regeneration, super cial wrinkles correction

    • Visibly results in quality of the skin• Ultra-safe pro le thanks to Bacillus subtilis

    Concentration18 mg/ml of HA, non cross-linked

    Syringe2 x 2,5 ml (available soon), 1 x 1 ml, 1 x 5 ml

    Contains• 0,01% of CaHA• Glycine and L-Proline

    IndicationHydratation, revitalization,collagen stimulation

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    The success of the treatment dependsto a great extend from the quality ofthe product injected and the repeatedsessions.

    Neauvia Organic Hydro Deluxe contains18 mg/ml of pure hyaluronic acidderived from Bacillus subtilis. Such

    high concentration allows to obtain very good results noticeable from thefirst treatment. It contains also 0,01%of calcium hydroxyapatite for additionalcollagen stimulation which makes theeffects of the therapy even better.

    A series of 4 treatments with 3 week intervalsbetween all treatments should be performed to

    achieve optimal results. At the end of the series,in order to maintain results, it is worth offering thepatient a follow-up treatment scheduled for half a year later.

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    neck and shouldersregeneration

    Hydro Deluxe

    skin firmingHydro Deluxe

    elbows and kneesregenerationHydro Deluxe

    strech marksreduction

    Hydro Deluxe

    HANDS REJUVENATIONFilling: Stimulate , Rheology

    Mesotherapy: Hydro Deluxe

    modelingof intimate parts

    Intense Rose

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    effectivesolutions

    crow’s feetREDUCTION

    fine linesRheology

    TEAR TROUGHRheology

    FACE CONTOURS LIFTINGIntense , Stimulate

    NOSE MODELING Intense

    cheek MODELING

    Intense , Stimulate

    CHIN MODELINGIntense , Stimulate

    NASO-LABIAL FOLDS FILLINGIntense , Stimulate , Rheology

    LIPS AUGMENTATIONIntense Lips , Rheology

    ACNE SCARS REDUCTIONStimulate , Rheology

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    intense manBIO ACTIVE FILLER

    Being aware of the differences in the men and women tissueas well as their subjective expectation from the aestheticmedicine we are proud to present the rst and uniqueproduct dedicated for men - Intense Man. A speci c formula with the highest concentration of HA (28mg/ml) and high viscosity of this product suits perfectly for thicker skin andmore rapid process of aging. Intense Man can be used to add volume in the sagging area and to ll the folds and deep wrinkles. Like all Neauvia llers it was made from the purestsource of hyaluronic acid (Bacillus subtilis) and cross-linked with PEG polymer (IPN technology).

    Benefits

    • The highest concentration of hyaluronic acid foref ciency and longevity

    • Unique worldwide product dedicated for men

    • Highest quality raw materials (BSHA and PEG )

    • Slow biodegradation and long lasting results

    Concentration28 mg/ml of HA, cross-linked with PEG

    Syringe1x 1ml

    IndicationRestoration of volume, lling of skindepression (included deep wrinkles andnasolabial folds)

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    CATALOGUE | PRODUCTS | FILLERS | for man

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    Processes of aging and skin structure of men differs from woman’s and the results are different with the aging. Their tickerskin lose volume, density and elasticity of tissue. To reduce thesigns of passing years and keep the young, energetic appearanceit is important to treat it holistic. Stimulate Man is a rst llerdedicated to help ghting the time in two ways. 28 mg/ml ofhyaluronic acid and high viscosity of the hydrogel ll tissue de citsfor a long time. The addition of 1% of calcium hydroxyapatitegives extra stimulation effect by activating broblasts to collagenstimulation. Stimulate Man is made from hyaluronic acid derivedfrom Bacillus subtilis and it is cross-linked by PEG polymer usinga real IPN technology. Calcium hydroxyapatite used in Neauvia

    llers has small particle size (8-12 microns) and is well spread andcross-linked in the hydrogel. This assure stability of the particlesthat have no possibility to migrate.

    Benefits

    • Unique combination of lling and biostimulation• High viscosity of the hydrogel for better adaptation to

    man’s tissue

    • Clinically proved results

    • Ultra-safe pro le thanks to Bacillus subtilis and PEG

    • Slow biodegradation and long lasting results

    Concentration• 28 mg/ml of HA, cross-linked with PEG

    • 1% of CaHA

    Syringe1x 1ml

    IndicationRestoration of volume, lling of skindepression (included deep wrinkles and

    nasolabial folds), collagen stimulation

    stimulate manBIO ACTIVE FILLER

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    effectivesolutions

    face revitalisingHydro Deluxe

    crow’s feet reductionHydro Deluxe

    frown linesRheology

    vertical lips linesRheology

    nose modellingIntense Man

    filling of skin depressionIntense Man

    face volumisingIntense Man , Stimulate Man

    sagging skinStimulate Man

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    EXAMPLESOF THE

    EFFECTS

    before after

    before after before after

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    CATALOGUE | PRODUCTS | EFFECTS

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    before

    after

    before after before after

    before after

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    intense intense LV intense lips intense rose

    hyaluronic acidcontent 28 mg/ml 26 mg/ml 24 mg/ml 28 mg/ml

    amino acids andcalciumhydroxyapatite

    content

    - - - -

    crosslinkingwith PEG X X X X X X X X X X X X X X X X X X

    syringe 1 x 1 ml 1 x 1 ml 1 x 1 ml 1 x 1 ml

    SPECIFICATION

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    CATALOGUE | PRODUCTS | specifications

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    stimulate rheology hydro deluxe intense man stimulate man

    26 mg/ml 22 mg/ml 18 mg/ml 28 mg/ml 28 mg/ml

    1% CaHA Glycine and L-Proline0,01% CaHA,Glycine andL-Proline

    - 1% CaHA

    X X X X X X X X - X X X X X X X X X X

    1 x 1 ml 1 x 1 ml

    1 x 1ml

    1 x 5 ml2 x 2,5 ml 1 x 1 ml 1 x 1 ml

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    CATALOGUE | PRODUCTS | COSMECEUTICALS

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    Complete your treatment with llers using our new NeauviaCosmeceuticals , a line of professional skin care products that

    prolong the effects of ller therapy.

    Thanks to the special formulation using the most effective

    active ingredients the products have strong anti-in amma -tory and anti-aging properties.

    In the line there are products for a daily use as well as forprofessional therapies in the clinics and beauty salons.

    DISCOVER

    Cosmeceuticals range

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    INTENSIVE CARE AFTERAESTHETIC MEDICINETREATMENT

    Modern aesthetic medicine treatments providepatients with long-lasting improvement of appearance,

    resulting in a higher request of cosmetic treatments.

    However, any invasive procedure may lead to differentlevel of side effects associated with the damaging ofthe skin layers. No matter which treatment has beencarried out, peeling or injection, it is important notonly to respect the protocols, but also to minimize the

    discomfort and to reduce the recovery period.

    Based on an advanced knowledge and researches aboutdermo-cosmetics, Neauvia Cosmeceuticals have beencreated to reduce both the in ammation after aestheticmedicine procedures and the aging process, even on themost sensitive and delicate skin.

    All creams and serums of Neauvia Cosmeceuticals areenriched with 2 main ingredients:

    3D HA Fractional System : an innovative conceptobtained through a unique process that enriches

    products with HA molecules with 3 differentranges of molecular weight. Due to their nature,they penetrate different layers of the skin, givingbirth to a 3D uniform structure in the skin:shorter chains will penetrate deeper than longerones building up a homogeneous and effectivesystem to restore the in amed or aged skins.

    Bene ts:• Restoration and optimal hydration• Aging prevention• Healing properties• Natural barrier for the skin: preventing

    aggressions and preserving the right nutrients• Immediately visible effects• Enhancement of skin brightness• Improvement in skin texture,• Improve Improvement in eskin elasticity and tone

    1

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    Growth Factors : substances thatstimulate cells division and growth,supporting the natural regenerationprocess; they are completely safeand do not cause allergic reactions.The complex of growth factors KGF(keratinocyte growth factor) & EGF(epidermal growth factor) used in Neauvia Cosmeceuticals promotes:

    • Renewal of the epidermis• Rapid recovery of the optimal level ofhydration

    • Ability of the epidermis to retainmoisture

    • Restoration of the skin structure• Enhancement of collagen and elastin

    synthesis• Activation of the cell metabolism• Promotion of intensive nutrition• Activation of the natural protective

    function of the skin

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    A unique and professional systemthat triggers the biological processof skin renewal at the cellular level with slight exfoliation and restoreaction; the unicity is determinedby the possibility to completely

    customize the treatmentsaccording to patients’ needs thatmight change from session tosession.

    The effectiveness of the productsis achieved by a specially selectedrange of acids (Peel vials) thatgently exfoliates the dead skin cellsand act in synergy with variousmoisturizing and regeneratingactive components (Active vials),all enriched with growth factors,

    that normalize the process ofrenewal of the epidermis, restorethe hydro-lipid balance of the skinand stimulate the production ofcollagen and elastin.

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    CATALOGUE | PRODUCTS | COSMECEUTICALS

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    Improvement of the skin toneand texture

    Smoothing of the newrinkles and roughness

    Hydration and rejuvenationof the skin

    Brightness of the skin

    Improvement in skinthickness

    Depending on different needs, doctors selectand mix the correct Active vials and Peel vials(not more then 3), with the delivery mask (thepeel-off mask included in the kit) and providean effective and personalized treatment for any

    patient. The delivery mask, besides containinggrowth factors and fractional HA, is enriched with plant extracts, which have excellentcalming and anti-in ammatory action reducingirritation.

    Neauvia Restore System cannot be compared

    with any other peeling, because of thecontrollable impact both super cially and indepth. Neauvia Restore System is softer, morenatural and gentle. It is not only exfoliating,but also regenerating the skin, giving it a stronglifting effect while activating the mechanism ofcell regeneration, increasing the micro-reliefand improving the complexion.

    Already after the rst treatment, patientsenjoy a softer, smoother and brighter skin with a healthy color and natural glow. Aftercompleting a certain number of sessions,

    depending on the skin condition, patients willachieve long lasting results due to a prolongedaction of collagen and elastin stimulation, which will result in hydrated and rejuvenatedskin with improved elasticity and rmness.

    Results:

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    CATALOGUE | PRODUCTS | COSMECEUTICALS

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    RIGEN MASK – POST TREATMENT RECOVERY MASK

    Neauvia Restore Rigen is a professionalmask, which ghts against all signs of aging,eliminating ne lines, providing lifting effectand protecting cells from photo-aging. It hasa unique structure that, in combination withthe active ingredients, “wakes up” the skin,effectively moisturizing and improving bothskin tone and elasticity.

    The mask consists of peptides and hyaluronicacid: Peptides imitate the effect of the growthfactors that are naturally present in our skin,controlling the metabolism of the cells due totheir regenerating, anti-wrinkle, anti-aging,and moisturizing properties.

    Peptides (oligopeptide-1-2,polypeptide-1-3-5-9-11 and coppertripeptide-3) combined with collagen givelifting effect and prevent the appearance of

    new wrinkles.

    Hyaluronic acid supports collagen synthesis,creating a protective layer on the surface ofthe skin and speeding up its regeneration.

    Suitable for all skin types.

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    REBALANCING LINE

    Both male and female lines of creams are

    based on the 3D Fractional Hyaluronic Acid,a skin re-hydrating agent, which quicklypenetrates the skin providing moisturizing.Furthermore, ATP-enzymes provide theskin cells with the necessary energy fortheir activities. At last, lenitive ingredientsassure a great anti-in ammatory andcalming effect. The line includes also somecurative Make Up (3 colors) that ensure not

    only perfect coverage of the skin, but alsosoothing and regeneration properties.

    Neauvia Cosmeceuticals creams have 5 different linesfor different purposes and goals to archive; all productscombine soothing, anti-in ammatory and strong

    regenerative effects. Applied on a regular basis, theyensure an appropriate skin moisture level together with a brilliant and natural appearance.

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    VITAMIN C LINE

    All Neauvia Vitamin C products containthe Ascorbyl-tetraisopalmitate that isthe most stable and durable molecule ofVitamin C known in chemistry; it has anexcellent percutaneous absorption and animportant role as vital component for skincare and anti-aging. Vitamin C, with theantioxidant actions, reduces the intensityof the skin redness, strengthens blood vessels and improves skin color whilestimulating the synthesis of collagenand protecting the skin from the adverseeffects of sun exposure. The line containsalso Coenzyme Q10 that protects skins atthe cellular level together with a strongand effective mix of antioxidants. It has tobe remarked that Vitamin C serum is theonly product on the market with a 30%concentration of Vitamin C.

    CONTOUR EYE LINE

    Products containing only low molecular weight Fractional Hyaluronic Acid, whichpenetrates deeper in the skin with ahighly moisturizing effect; both creamsand serum have a very light texture fora quick absorption that improves skinelasticity, which is extremely important incase of sensitive and delicate areas. Theline contains also 2 peptides providingan immediate lifting effect, something allpatients are looking for in such product.

    REJUVENATION ROSE

    It is a delicate intimate gel for a daily use with a strong softening, hydrating and

    lling out effect, which accelerates therecovery process of the epidermis, so thegel can be applied also on the irritated skin.In addition, it preserves the natural pH ofintimate areas - pH 4.5 - and enhances theprotective properties of the mucosa. It is tobe remarked that this gel is including boththe EGF and KGF growth factors.

    SILK BODY LINE

    The products are suitable for body care.Growth factors, both EGF and KGF,stimulate the cell replication and activities,slowing down the aging process. Silkproteins smoothen the skin, providing anextremely pleasant sensation to the touch.The particular composition of the serummakes the product absolutely not sticky, soit do not damage clothes.

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    CATALOGUE | testimonials

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    TESTIMONIALS

    Dr. Andrzej IgnaciukAesthetic Medicine Specialist

    Dr. Doncho Etugov Dermatosurgeon

    Dr. Med. Agnese RuskuleAesthetique Medicine Specialist

    Prof. Nicola ZerbinatiSpecialist in Dermatology & Venerology Assistant Professor, University of Varese Italy

    Paweł KubikAesthetique Medicine Specialist

    Krzysztof MirackiCertified Aesthetic Medical Doctor, ENT and laser specialist

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    “Dear colleagues, I amdermatosurgeon andspecialist in estheticmedicine. During myprofessional experienceI had use many differentproducts including HA

    llers. After I discoverNeauvia I feel secure

    and satis ed. Why? Because this producthas the best safety pro le on the market -no single side effect reported by doctors.

    Because of the new type of HA extractionbased on water and new cross linking pro-cess based on polyethylene glycol (PEG)replacing BDDE. At the same time, usingNeauvia I cover all patient expectations -good feeling and volumizing effect imme-diately after the procedure and long lastingeffect, thanks to tissue stimulation due tocalcium hydroxyapatite. As a prolonged ef-fect I observe collagen and elastin produc-tion, as a result of broblast stimulation.So, if you want to discover the magic of thenew type of HA ller, combined with cal -cium hydroxyapatite, become a member ofa team of Neauvia injectors.”

    “When 25 years ago I have startedto practice aesthetic medicine, therange of possible defects correc-

    tions had been very limited. Luckily,thanks to incredible progress in thiseld, today we have choice between

    numerous tissue llers, includingnew Neauvia Organic line. This prod-ucts includes well known and safeproperties of hyaluronic acid in thepurest possible form and calcium hy-droxyapatite, which stimulate body tocollagen production. Thanks to thisfeatures Neauvia product are highlyinnovative, give natural and longlasting effect and, what is the mostimportant, are safe for patients”.

    “The new generation fillers Neauvia are very strong com-petitor among represented offers in the market. Neauviaproducts are covering extensive skin anti-age indicationspectrum and allow perform the procedure at the high-

    est level. The quality and price level correlates with theadvancement of science”.

    Dr. Med. Agnese RuskuleAesthetique Medicine Specialist

    Dr. Andrzej IgnaciukAesthetic Medicine Specialist Dr. Doncho Etugov

    Dermatosurgeon

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    “The most important aim of modern aesthetic medicine is notonly to have good effect but also to choose the best instruments.

    Neauvia Organic line connects safety of the patients with na-tural, long lasting results. I especially appreciate working withNeauvia Organic Stimulate which combines the purest form ofhyaluronic acid with calcium hydroxyapatite thanks to what it

    lls the tissues and stimulates collagen production”.

    “Neauvia is derived from the world’s rst and only recombinant manufacturing process which isbased on fermentation of safe and nonpathogenic bacterial strain Bacillus subtilis. The resultingsodium hyaluronate material is characterized by an unmatched purity and particularly low amountsof nucleic acids, proteins, bacterial endotoxins, and microbial contamination which are believed toreduce hypersensitivity reactions when the material is injected either as linear or crosslinked HA.The ultrapurity and reproducible molecular properties of BSHA (Bacillus Subtilis Hyaluronic Acid)and the new PEG crosslinking can indeed contribute to the safety, consistency, and robustness of

    nal products”.

    Prof. Nicola ZerbinatiSpecialist in Dermatology & VenerologyAssistant Professor, University of Varese Italy

    Paweł KubikAesthetique Medicine Specialist

    “I have been using Neauvia products ever since they had rst appeared on the market,and now I use them on a daily basis. I favor Neauvia because it offers a wide variety ofproducts, which I can use to suit the needs of many of my patients. The advantage ofusing these agents comes form the fact that I can be assured of a patient’s safety and wellbeing. I can use it to achieve excellent, natural, and long lasting effects due to theorganic nature and biocompatibility of the substances. Over time the more I use it the

    more I become convinced of it’s superiority when compared to other hyaluronic acidagents”.

    Krzysztof MirackiCertified Aesthetic Medical Doctor,ENT and laser specialist

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