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Michael W Hodin, Ph.D.
Executive Director, Global Coalition on Aging
Managing Partner, High Lantern Group
Alzheimer’s: A 21st Century Fiscal and
Social Imperative
“No other force is likely to shape the future of
national economic, health, public finances, and
policymaking as the irreversible rate at which
the world’s population is aging.”
—Standard & Poor's
“Global Aging 2010: An Irreversible Truth”
2
3
Substantial Growth of Older Population
609 million 1 billion 2 billion
0%
20%
40%
60%
80%
100%
2000 2020 2050
60+
15-59
0-14
2 billion over 60
0%
20%
40%
60%
80%
100%
2050
60+
15-59
0-14
Most Dramatic Growth Among 85+ Population
The risk of dementia jumps from 1 in 8
for those over the age of 65 to 1 in 2.5
for those over 85.
4
191 million
people over
85 by 2050
60+ Population
60-84 Years Old
So
urc
e: W
orldM
appe
r.o
rg a
nd
Age
Wave
estim
ate
s
The Number of Alzheimer’s Cases 1900 (est.)
Note: Each dot represents 100,000 cases of Alzheimer’s 5
So
urc
e: W
orldM
appe
r.o
rg a
nd
Age
Wave
estim
ate
s
Note: Each dot represents 100,000 cases of Alzheimer’s
The Number of Alzheimer’s Cases 1950
6
So
urc
e: W
orldM
appe
r.o
rg a
nd
Age
Wave
estim
ate
s
Note: Each dot represents 100,000 cases of Alzheimer’s
By 2000, we have an epidemic
7
So
urc
e: W
orldM
appe
r.o
rg a
nd
Age
Wave
estim
ate
s
Note: Each dot represents 100,000 cases of Alzheimer’s
By 2050, Alzheimer’s transforms
from health crisis to fiscal nightmare
8
Today 2030 2050
Co
sts
& P
revale
nce
$604 billion;
1% of Global GDP
With investment
in treatment, care,
and prevention
Without investment
in treatment, care,
and prevention
115 million cases
9
Costs and Rates Will Soar Without a Breakthrough
36 million cases
Dementia is a Global Challenge
10
“The consequences of dementia for societies and
economies are devastating everywhere, in high-income
countries and low- and middle-income countries alike..”
-The World Health Organization
“Nearly two-thirds of all people with dementia live in low
and middle income countries, where the sharpest
increases in numbers are set to occur.”
- Alzheimer’s Disease International, World Alzheimer Report 2010
11
Dementia is Becoming a Top Priority
“Dementia doesn’t just affect individuals.
It also affects and changes the lives of family members.
Dementia is a costly condition in its social,
economic, and health dimensions.”
—WHO Director-General Margaret Chan
“The Obama administration has announced a bold research
program to test whether a drug can prevent the onset of
Alzheimer’s disease...the payoff could be huge.”
—New York Times, 20 May 2012
“Dementia is a ticking time bomb.”—Dr. Peter Piot
Dementia Is on the Global Agenda
United Nations
NCD
Outcomes
Document
WHO
Standalone report
on Alzheimer’s
Alzheimer’s
Disease
International
Reports
Global Coalition
on Aging
Links to AD Driving
Challenge
OECD
Meetings and
Agendas
Growing Global
Media Interest
ADNI
Collaboration
12
But We Are Not Where We Need To Be.
13
14
100% Incurable
&
100% Fatal
Alzheimer’s Disease is
15
How Do We Advance Progress?
New Care Models
Re-invent Care that draws on the best private sector innovation
Remove Stigma
We think progress is impossible
Improve Regulatory Environment
Stuck in 20th century regulatory models
Motivate Patient Advocacy
Create a Movement -- driven, motivated, political
16
New Care Models
Re-invent Care that draws on the best private sector innovation
Remove Stigma
We think progress is impossible
Improve Regulatory Environment
Stuck in 20th century regulatory models
Motivate Patient Advocacy
Create a Movement -- driven, motivated, political
How Do We Advance Progress?
17
New Care Models
Re-invent Care that draws on the best private sector innovation
Remove Stigma
We think progress is impossible
Improve Regulatory Environment
Stuck in 20th century regulatory models
Motivate Patient Advocacy
Create a Movement -- driven, motivated, political
How Do We Advance Progress?
18
New Care Models
Re-invent Care that draws on the best private sector
innovation
Remove Stigma
We think progress is impossible
Improve Regulatory Environment
Stuck in 20th century regulatory models
Motivate Patient Advocacy
Create a Movement -- driven, motivated, political
How Do We Advance Progress?
19
New Care Models
Re-invent Care that draws on the best private sector innovation
Remove Stigma
We think progress is impossible
Improve Regulatory Environment
Stuck in 20th century regulatory models
Motivate Patient Advocacy
Create a Movement -- driven, motivated, political
How Do We Advance Progress?