Nausea & VomitingDarrell R. Latva, D.P.M.Founder: Mt. Sinai Residency

At least after death youre not nauseous Woody Allan in Sleeper

The Goals and Objectives for Today:IntroductionPhysiologyHistory, History, HistoryTreatment

Introduction

CommonMultifactorial$ $ $ + TimeBut most importantly is.?

Physiology

History, History, History

Who needs prophylaxis?The Duke University studyFactors under your controlFactors not under your controlMulti-modal therapy: a concept that works

Treatment of PONV

Somewhere around eighteen drugs have been utilized, at one time or another, to treat PONV. These include

SteroidsDexamethasoneButyrophenones (D2 antagonist)Droperidol (Black box!)Benzamides (D2 antagonist)MetoclopramideAntihistamines (H1 antagonist)PromethazineM1 antagonistsScopolamine5HT3 antagonistsOndansetronNK1 antagonist (SPA)Aprepitant

The End!