-
7/25/2019 Natl J Maxillofac Surg
1/9
Natl J Maxillofac Surg. 2013 Jan-Jun; 4(1): 4045.
doi: 10.41030!"5-5!50.11"##0$M%&': $M%3#003#3
Evaluation of the efficacy of AgNOR as a
proliferative marker in oral leukoplakia: A
morphometric analysis
aita Niti*+ ,arg in//t a1and S+al//n %+andra1
ut+or inforation %o6rig+t and 7ic/n*/ inforation ,o to:
Abstract
Background:
Sil/r *taina8l/ nucl/olar organi9/r r/gion* (gN*) ar/ r/licator6
ar/r*
-
7/25/2019 Natl J Maxillofac Surg
2/9
>o conclud/ t+/ gN count i* t+/ o*t aroriat/ ar/r to
diff/r/ntiat/ 8/t
-
7/25/2019 Natl J Maxillofac Surg
3/9
at+ological) +/ */cond grou na/d a* d6*la*tic l/uolaia('7)
con*i*t/d of od/rat/ /it+/lial d6*la*ia *//r/ d6*la*ia and carcinoa
in situ.
Iollo+/ 8/*t four +otogra+* r/garding t+/ ictur/ ?ualit6
+/ +otogra+*
-
7/25/2019 Natl J Maxillofac Surg
4/9
ar/a +/ o8tain/d r/*ult* otal gN ar/a100
gN $roortion M/an gN ar/a/an nucl/ar ar/a.
>+/ r/*ult*
-
7/25/2019 Natl J Maxillofac Surg
5/9
>a8l/ 2
%alculation of anal6*i* of arianc/ of gN in ariou* ara/t/r* in
8/ta8l/ 3*+o
-
7/25/2019 Natl J Maxillofac Surg
6/9
* *//n fro t+/ r/*ult* of t+i* *tud6 t+/ /an gN count /r nucl/u*
+/ gN count *+o
-
7/25/2019 Natl J Maxillofac Surg
7/9
noral oral /it+/lial to 8/nign l/*ion* and to S%%. '/r/n9ini et
al. /aluat/d nucl/olar *i9/
u*ing *il/r *taining in 10 tuor c/ll lin/* and found t+at
nucl/olar *i9/ can r/lia8l6 indicat/ t+/
raidit6 of c/ll rolif/ration. >+/6 o*tulat/d t+at t+/ +ig+/r
gN rot/in alu/ corr/*ond*to a +/ r/*ult* of our *tud6 ar/
con*i*t/nt
-
7/25/2019 Natl J Maxillofac Surg
8/9
>+u* t+/ r/*ult* of t+/ r/*/nt *tud6 *+o< a lin/ar
r/lation*+i 8/t+/ or+o/tric
ara/t/r* *+o< a o*iti/ tr/nd. >+/ir rol/ in diagno*i* of
/it+/lial d6*la*ia i* *till *u8/ct tofurt+/r in/*tigation.
&n *uar6 r/*ult* indicat/ a c+ang/ in t+/ N att/rn in oral
uco*al l/*ion* (d6*la*tic andnond6*la*tic l/uolaia)
-
7/25/2019 Natl J Maxillofac Surg
9/9
#. Sc+ S+/ila N =/i* Madar V /t al. **/**/nt of t+/
nucl/olarorgani9/r r/gion* 86 autoat/d iag/ anal6*i* in 8/nign and
alignant colonic tuor* and
adac/nt ti**u/* in rat*. J %o $at+ol. 1!!5;113:4550.
@$u8M/dA
22. ,on9al/9 $ uar ' SWnc+/9 7. gN ar/a /a*ur//nt* diff/r/ntiat/
8/nign and
alignant /lanoc6tic l/*ion* or/ accurat/l6 t+an *il/ counting. J
'/ratoat+ol.1!!4;1C:3"2C. @$u8M/dA
23. 7o Mu9io 7 Mignogna M' Stai8ano S d/ ico , Salator/ , daiano
S /t al.
Mor+o/tric *tud6 of arg6ro+ilic nucl/olar organi9/r r/gion* in
G$-a**ociat/d r/canc/rou*l/*ion* and icroina*i/ carcinoa of t+/
oral cait6. ral ncol. 1!!";33:24"5!. @$u8M/dA
24. %a8rini 7 Sc+
