Nanomark is a company that develops products which make nucleic acids research more practical

Partnerships: leading institutes like CSEM

Brasil

Production

Ph.D. team: Immunologists,

Biochemists, Physicists

Research and Development

Direct sales: easy way to reach the final client

Commercialization

The company’s value proposition is to ease research

and experiments on nucleic acids

First lauch of Nanomark will be a magnetic nanocomposite that purifies nucleic acids samples in an efficient way

1mg/assay No need to maintain in cold

Fast

Results in 15 minutes

1 3

No impact on the labs’ refrigerators

No heating of the nanocomposite

Results in less than 15 minutes

No need to use other lab’s special devices

Minimum Material

Room Temperature

No phenolic compounds

Ecofriendly

4

Easily disposable

No need of any special waste treatment

Use of 1 gram for 100 experiments

Effi

cie

ncy

+

2

Nanomark’s nanocomposite is also useful for other applications than purification of nucleic acids: Magnetism, Fluorescence and Adjuvancy

Magnetism

Adjuvancy

Other Usabilities How it could be used Process

Driving nuclei acids to specific locations

Using magnetic field-based devices

Direction

Visualization

Fluorescence

Tracking

Sensivity

Possibility to Real-time tracking of the nanocomposites

Fluorescence increases signaling/sensitizing in certain assays

Immunization Nanocomposites, by itself, can be act

as immunoadjuvants in immunization protocols

Some reagents used on the process are harmful to human beings

Need to treat the leftovers before its discharge on regular waste

Unsafe to the environment

Incubation/ Centrifugation

Washing/Tubes replacement

Incubation/ Centrifugation

Elution Results

1 5 2 3 4 DNA purification commercial kits

Current purification processes take twice as much time as Nanomark’s nanocomposite, use harmful chemicals and are expensive

Money

Harmful Chemicals

Cost per experiment of approximately U$ 8,00

Less usability

Incubation Washing/Tubes

replacement Incubation/

Centrifugation Elution Results

1 3 2

30 minutes

15 minutes

When compared with other commercial kits, the nanocomposite shows promising results combined with an easy procedure

Great results adding the Nanocomposite Balancing quantity and quality

DNA Purification without commercial kits

Nanomark Alcohol Based Nanomark Kit 1 Kit 2

DNA Purification with commercial kits

DNA Amount DNA Purity

Hardly any DNA is lost, comparing with traditional purification methods and there is an important

fluorescence in Nanomark’s compound

DNA is obtained with high degree of purity and a satisfactory amount

1. Important success history in Seed and Venture Capital

2. Profound knowledge in the health care market

3. Many partnerships aiming technological development

4. Corporate Governance and Management Practices history

Nanomark is a company in the FIR Capital ecosystem, which has a wide track record of seed and venture capital investments as well as start up management

2

Board Member Maintainer 2 coinvestments

Cofounder Board Member Market – Academy bridge

Integrated Business Developer Private Equity and Venture

Capital New Ventures Financial Advisory

4

Best team INOVAR and FINEP prize winner 2009

Corporate Governance INOVAR prize winner 2011

1

3

Production will take place at CSEM Brazil a worldwide reference in development and innovation

Imperial College

London

Supporters:

Centro de P&D suíço 4 Labs

Neuchatel Basel Landquart Zurich Alpnach

Leaders:

Sciense and Knowledge City Belo Horizonte, MG

Team

21 researches with exclusive dedication

11 nationalities

9 doctors

9 masters

Academic Production

25 registered patents

Over 90 publications

U$ 300 MM in intellectual production transactions

Nanomark’s team has extensive scientific experience, access to the most advanced research centers and a successful history of business structuring

GUILHERME Emrich

Biobrás Chairman from start-up until the company became world’s

4th biggest insulin producer and top five performance in Brazilian

stock market;

BioMinas Foundation Founder;

Brazilian Science and Technology Council Member

DAVID Travesso Neto

Alcan Aluminum Executive, World Markets;

AES Group Executive, CEMIG and Eletropaulo Ex Vice President

Former CEMIG, Geração Tiete, Telemig, Amazonia Celular, Infovias

and WayBrasil Board Member

Sebrae-MG former Executive Director

Rodrigo Corrêa Oliveira, Ph.D.

Ph.D. in immunology at John Hopkins University, USA

Member of the Brazilian Science Academy

FIOCRUZ’s former director: René Rachou Institute

TDR WHO Member and former Vice President

Thank you!